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Home  > 4-Amino-7-chloroquinoline

AA33060

1198-40-9 | 4-Amino-7-chloroquinoline

Packsize Purity Availability Price Discounted Price    Quantity
100mg 95% in stock $14.00 $10.00 -   +
250mg 95% in stock $17.00 $12.00 -   +
1g 95% in stock $66.00 $46.00 -   +
5g 95% in stock $246.00 $172.00 -   +
25g 95% in stock $1,008.00 $706.00 -   +

*All products are for research use only and not intended for human or animal use.

*All prices are in USD.

Description
Catalog Number: AA33060
Chemical Name: 4-Amino-7-chloroquinoline
CAS Number: 1198-40-9
Molecular Formula: C9H7ClN2
Molecular Weight: 178.6183
MDL Number: MFCD00828822
SMILES: Clc1ccc2c(c1)nccc2N
NSC Number: 13

 

Computed Properties
Complexity: 163  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 12  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 1  
XLogP3: 2.3  

 

 

Upstream Synthesis Route
  • 7-Chloroquinolin-4-amine, also known as $name$, serves as a versatile building block in chemical synthesis due to its unique structural features and reactivity. This compound is commonly employed as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals.One prominent application of 7-Chloroquinolin-4-amine is in the development of antimalarial drugs. By utilizing this compound as a precursor, chemists are able to introduce specific functional groups and modifications to the quinoline ring system, enhancing the potency and selectivity of the final drug candidate. The presence of the chloro group at the 7-position provides a valuable site for further derivatization, allowing for the fine-tuning of biological activity.Additionally, 7-Chloroquinolin-4-amine plays a crucial role in the synthesis of fluorescent dyes and imaging agents. Through strategic chemical transformations, researchers can incorporate this compound into the molecular structure of fluorescent probes, enabling the visualization of biological processes and interactions at the molecular level. The innate fluorescence properties of quinoline derivatives make them valuable tools in biological research and diagnostics.Furthermore, 7-Chloroquinolin-4-amine is utilized in the preparation of complex natural products and heterocyclic compounds with diverse biological activities. By harnessing the reactivity of the quinoline scaffold, chemists can access a wide array of structurally intricate molecules that exhibit promising pharmacological properties. The versatility of this building block enables synthetic chemists to access novel chemical entities with potential therapeutic relevance.Overall, the strategic incorporation of 7-Chloroquinolin-4-amine in chemical synthesis enables the creation of innovative compounds with applications spanning drug discovery, materials science, and chemical biology. Its role as a key intermediate highlights its significance in the construction of molecular libraries and the development of biologically active compounds.
Literature
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