1199-77-5 | Alpha-methylcinnamic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$9.00	$6.00
25g	98%	in stock	$15.00	$10.00
100g	98%	in stock	$30.00	$21.00
500g	98%	in stock	$108.00	$75.00

Description

• Catalog Number: AA33300
• Chemical Name: Alpha-methylcinnamic acid
• CAS Number: 1199-77-5
• Molecular Formula: C10H10O2
• Molecular Weight: 162.1852
• MDL Number: MFCD00002652
• SMILES: C/C(=C\c1ccccc1)/C(=O)O

Computed Properties

• Complexity: 188
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.2

Upstream Synthesis Route

α-Methylcinnamic acid is a versatile compound widely used in chemical synthesis. Its unique structural properties make it valuable in various applications, especially in the production of fragrances, pharmaceuticals, and agrochemicals. In chemical synthesis, α-Methylcinnamic acid serves as a key intermediate in the creation of many important organic compounds. It can undergo various reactions such as esterification, oxidation, and reduction to yield a diverse range of derivatives. α-Methylcinnamic acid's ability to participate in these transformations allows chemists to tailor its structure for specific desired properties, making it a valuable building block in the development of new molecules with enhanced biological activities or improved performance characteristics. Its role in chemical synthesis extends to the creation of flavors, dyes, and other specialty chemicals, highlighting its importance in the development of innovative products across different industries.

Literature

• Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: the role of IL-6 signaling and Nrf2/AKR1C axis identification.

  Biochemical pharmacology 20131001

• Reduction of doxorubicin and oracin and induction of carbonyl reductase in human breast carcinoma MCF-7 cells.

  Chemico-biological interactions 20081022

• Cinnamic acids as new inhibitors of 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3).

  Molecular and cellular endocrinology 20060327

• Achiral ligands dramatically enhance rate and enantioselectivity in the Rh/phosphoramidite-catalyzed hydrogenation of alpha,beta-disubstituted unsaturated acids.

  Angewandte Chemie (International ed. in English) 20050704