119910-45-1 | 2-Bromo-1h-indole-3-carbaldehyde

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$212.00	$148.00
1g	95%	in stock	$455.00	$318.00

Description

• Catalog Number: AE16747
• Chemical Name: 2-Bromo-1h-indole-3-carbaldehyde
• CAS Number: 119910-45-1
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.0540
• MDL Number: MFCD18449874
• SMILES: O=Cc1c(Br)[nH]c2c1cccc2
• NSC Number: 622163

Computed Properties

• Complexity: 185
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.5

Upstream Synthesis Route

2-Bromo-1H-indole-3-carbaldehyde is a versatile compound widely utilized in chemical synthesis for its unique properties and reactivity. Within the realm of organic chemistry, this compound serves as a valuable building block in the creation of various complex molecules and pharmaceutical intermediates. Its strategic incorporation in synthetic pathways enables the introduction of an indole moiety, consequently imparting desired physicochemical characteristics and biological activities to the final products. Specifically, 2-Bromo-1H-indole-3-carbaldehyde is commonly employed in the synthesis of heterocyclic compounds, indole derivatives, and natural products. Its reactivity towards nucleophiles and ability to undergo diverse reactions make it an indispensable tool for generating structurally complex and diverse chemical entities.

Literature

• Synthesis of annulated gamma-carbolines and heteropolycycles by the palladium-catalyzed intramolecular annulation of alkynes.

  The Journal of organic chemistry 20030627