120-15-0 | 6-Methoxy-1,2,3,4-tetrahydroquinoline

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$24.00	$17.00
5g	97%	in stock	$114.00	$80.00
10g	97%	in stock	$170.00	$119.00
25g	97%	in stock	$424.00	$297.00
100g	97%	in stock	$792.00	$555.00

Description

• Catalog Number: AA33503
• Chemical Name: 6-Methoxy-1,2,3,4-tetrahydroquinoline
• CAS Number: 120-15-0
• Molecular Formula: C10H13NO
• Molecular Weight: 163.2163
• MDL Number: MFCD29037426
• SMILES: COc1ccc2c(c1)CCCN2
• NSC Number: 49188

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.3

Upstream Synthesis Route

6-Methoxy-1,2,3,4-tetrahydroquinoline is a versatile compound widely utilized in chemical synthesis for its unique properties and diverse applications. It serves as a valuable building block in the creation of various pharmaceuticals, agrochemicals, and specialty chemicals due to its structural significance and reactivity.Specifically, in chemical synthesis, 6-Methoxy-1,2,3,4-tetrahydroquinoline plays a crucial role as a key intermediate in the production of heterocyclic compounds, which are essential in drug discovery and development. This compound enables the construction of complex molecular structures through functional group transformations, including oxidation, reduction, and substitution reactions, leading to the efficient synthesis of biologically active molecules.Moreover, the presence of the methoxy group in 6-Methoxy-1,2,3,4-tetrahydroquinoline enhances its utility as a directing group for selective reactions, allowing chemists to control the regioselectivity and stereoselectivity of the chemical transformation. This feature makes it a valuable tool in the synthesis of natural products and other complex organic molecules with specific stereochemical requirements.Overall, 6-Methoxy-1,2,3,4-tetrahydroquinoline stands out as a versatile and indispensable compound in chemical synthesis, offering chemists a strategic platform for designing and accessing novel compounds with diverse functionalities and biological activities.

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101