120-51-4 | Benzyl benzoate

Packsize	Purity	Availability	Price	Discounted Price
100g	98%	in stock	$9.00	$6.00
500g	98%	in stock	$15.00	$10.00

Description

• Catalog Number: AA33525
• Chemical Name: Benzyl benzoate
• CAS Number: 120-51-4
• Molecular Formula: C14H12O2
• Molecular Weight: 212.24388000000002
• MDL Number: MFCD00003075
• SMILES: O=C(c1ccccc1)OCc1ccccc1

Computed Properties

• Complexity: 213
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 4

Upstream Synthesis Route

Benzoic acid, phenylmethyl ester is commonly utilized in chemical synthesis as a key raw material or reagent. This compound plays a vital role in the production of various important organic compounds through esterification reactions. By reacting benzoic acid, phenylmethyl ester with different alcohols or carboxylic acids, chemists can efficiently synthesize a wide range of ester derivatives. These esters find application in pharmaceuticals, flavors and fragrances, and other industrial processes. The versatility of benzoic acid, phenylmethyl ester makes it a valuable component in the toolbox of synthetic chemists, allowing for the creation of diverse and complex molecules.

Literature

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• An approach for a synthesis of asparagine-linked sialylglycopeptides having intact and homogeneous complex-type undecadisialyloligosaccharides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Fluorescent ligands for the hemagglutinin of influenza A: synthesis and ligand binding assays.

  Bioconjugate chemistry 20070101

• Synthesis and characterization of functional elastomeric poly(ester amide) co-polymers.

  Journal of biomaterials science. Polymer edition 20070101

• Diffuse acute pustular eruption after streptococcal infection--a new instance of pustulosis acuta generalisata.

  Pediatric dermatology 20070101

• Toxicity and efficacy of selected pesticides and new acaricides to stored product mites (Acari: Acaridida).

  Experimental & applied acarology 20070101

• Three-dimensional imaging of Drosophila melanogaster.

  PloS one 20070101

• Scabies: a ubiquitous neglected skin disease.

  The Lancet. Infectious diseases 20061201

• Whole insect and mammalian embryo imaging with confocal microscopy: morphology and apoptosis.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20061101

• The synthesis of alternative diketopiperazines as potential RGD mimetics.

  Journal of peptide science : an official publication of the European Peptide Society 20061001

• [Systemic adverse reactions with ivermectin treatment of scabies].

  Annales de dermatologie et de venereologie 20061001

• [Norwegian scabies, a rare diagnosis in Tunisia].

  La Tunisie medicale 20061001

• A comparison of tissue-engineered hyaluronic acid dermal matrices in a human wound model.

  Tissue engineering 20061001

• Dorsoventral patterning in hemichordates: insights into early chordate evolution.

  PLoS biology 20060901

• Estrogenic activity of phthalate esters by in vitro VTG assay using primary-cultured Xenopus hepatocytes.

  Dental materials journal 20060901

• Toxicity of spray and fumigant products containing cassia oil to Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae).

  Pest management science 20060801

• Confocal laser scanning microscopy of whole mouse ovaries: excellent morphology, apoptosis detection, and spectroscopy.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060801

• Efficacy and tolerability of a new synergized pyrethrins thermofobic foam in comparison with benzyl benzoate in the treatment of scabies in convicts: the ISAC study (Studio Della scabbia in ambiente carcerario).

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060701

• Food protective and color alteration effects of acaricidal aldehydes on Tyrophagus putrescentiae (Schrank).

  Journal of food protection 20060701

• [Ester prodrug of scutellarin: synthesis, physicochemical property and degradation].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060701

• Acaricidal activities of paeonol and benzoic acid from Paeonia suffruticosa root bark and monoterpenoids against Tyrophagus putrescentiae (Acari: Acaridae).

  Pest management science 20060601

• Scabies.

  Lancet (London, England) 20060527

• Toxicity of bisabolangelone from Ostericum koreanum roots to Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae).

  Journal of agricultural and food chemistry 20060517

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Clinical practices. Scabies.

  The New England journal of medicine 20060420

• Crusted scabies in an adult T-cell leukemia/lymphoma patient successfully treated with oral ivermectin.

  The Journal of dermatology 20060201

• Chemical-physical characterization and in vitro preliminary biological assessment of hyaluronic acid benzyl ester-hydroxyapatite composite.

  Journal of biomaterials applications 20060101

• Aluminum sulfate significantly reduces the skin test response to common allergens in sensitized patients.

  Clinical and molecular allergy : CMA 20060101

• [Crusted scabies (Norwegian scabies) a case report].

  Gaceta medica de Mexico 20060101

• In vitro release of insulin and biocompatibility of in situ forming gel systems.

  International journal of pharmaceutics 20051104

• Structure-activity studies of 3'-4'-dichloro-meperidine analogues at dopamine and serotonin transporters.

  Bioorganic & medicinal chemistry 20051001

• Design of wide-spectrum inhibitors targeting coronavirus main proteases.

  PLoS biology 20051001

• Free radical generation during chemical depolymerization of heparin.

  Analytical biochemistry 20050915

• Pthiriasis capitis.

  International journal of dermatology 20050901

• Few bicyclic acetals at reducing end of low-molecular-weight heparins: might they restrict specification of pharmacopoeia?

  Pharmeuropa scientific notes 20050801

• Food protective effect of acaricidal components isolated from anise seeds against the stored food mite, Tyrophagus putrescentiae (Schrank).

  Journal of food protection 20050601

• Risk factors of allergic rhinitis: genetic or environmental?

  Therapeutics and clinical risk management 20050601

• Controlled delivery of testosterone from smart polymer solution based systems: in vitro evaluation.

  International journal of pharmaceutics 20050513

• Anti-cancer ProTides: tuning the activity of BVDU phosphoramidates related to thymectacin.

  Bioorganic & medicinal chemistry 20050502

• Acaricidal activity of active constituent isolated in Chamaecyparis obtusa leaves against Dermatophagoides spp.

  Journal of agricultural and food chemistry 20050323

• SAR studies of brasilicardin A for immunosuppressive and cytotoxic activities.

  Bioorganic & medicinal chemistry 20050301

• Floral scent emission and pollinator attraction in two species of Gymnadenia (Orchidaceae).

  Oecologia 20050201

• Structure formation in injectable poly(lactide-co-glycolide) depots. II. Nature of the gel.

  Journal of biomedical materials research. Part B, Applied biomaterials 20050115

• Immunobiological [correction of Immunobioloical] activity of a new benzyl benzoate from the aerial parts of Solidago virga-aurea var. gigantea.

  Archives of pharmacal research 20050101

• In vitro release of levonorgestrel from phase sensitive and thermosensitive smart polymer delivery systems.

  Pharmaceutical development and technology 20050101

• Efficacy of various synthetic pyrethroid-impregnated encasement materials against house dust mite under laboratory conditions.

  Experimental & applied acarology 20050101

• Oligonucleotides conjugated to short lysine chains.

  Bioconjugate chemistry 20050101

• Effect of co-solvents on the controlled release of calcitonin polypeptide from in situ biodegradable polymer implants.

  Drug delivery 20050101

• [Disacarification in the prevention of allergic diseases].

  Gigiena i sanitariia 20050101

• Deazapurine solid-phase synthesis: combinatorial synthesis of a library of N3,N5,C6-trisubstituted pyrrolo[3,2-d]pyrimidine derivatives on cross-linked polystyrene bearing a cysteamine linker.

  Journal of combinatorial chemistry 20050101

• Volatile composition, emission pattern, and localization of floral scent emission in Mirabilis jalapa (Nyctaginaceae).

  American journal of botany 20050101

• Acaricidal activity of Paeonia suffruticosa root bark-derived compounds against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae).

  Journal of agricultural and food chemistry 20041229

• Design, synthesis, and photochemical behavior of poly(benzyl ester) dendrimers with azobenzene groups throughout their architecture.

  The Journal of organic chemistry 20041224

• In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability.

  Bioorganic & medicinal chemistry 20041215

• Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting.

  Pharmaceutical research 20041101

• The transmediastinal arteries of the human testis: an anatomical study.

  Surgical and radiologic anatomy : SRA 20041001

• Drug release from injectable depots: two different in vitro mechanisms.

  Journal of controlled release : official journal of the Controlled Release Society 20040930

• Cytocompatibility and viscoelastic properties of phthalate ester-free tissue conditioners.

  Dental materials journal 20040901

• Phytochemistry and preliminary biological evaluation of Cyathostemma argenteum, a malaysian plant used traditionally for the treatment of breast cancer.

  Phytotherapy research : PTR 20040701

• [Nosocomial infection of scabies in national hospitals and sanatoria in Japan].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20040701

• Acaricidal activity of constituents identified in Foeniculum vulgare fruit oil against Dermatophagoides spp. (Acari: Pyroglyphidae).

  Journal of agricultural and food chemistry 20040519

• Acaricidal activity of Melaleuca alternifolia (tea tree) oil: in vitro sensitivity of sarcoptes scabiei var hominis to terpinen-4-ol.

  Archives of dermatology 20040501

• An evaluation of Hyalofill-F plus compression bandaging in the treatment of chronic venous ulcers.

  Journal of wound care 20040501

• Genetic and molecular basis of grass cell-wall degradability. I. Lignin-cell wall matrix interactions.

  Comptes rendus biologies 20040501

• Synthesis of [323]-p-octiphenyls: orthogonal functionalization along a rigid-rod scaffold for refined supramolecular architecture.

  Organic letters 20040318

• p-Anisaldehyde: acaricidal component of Pimpinella anisum seed oil against the house dust mites Dermatophagoides farinae and Dermatophagoides pteronyssinus.

  Planta medica 20040301

• Controlled release of a model protein lysozyme from phase sensitive smart polymer systems.

  International journal of pharmaceutics 20040301

• Effects of sarcoptic mange and its control with oil of Cedrus deodara, Pongamia glabra, Jatropha curcas and benzyl benzoate, both with and without ascorbic acid on growing sheep: epidemiology; assessment of clinical, haematological, cell-mediated humoral immune responses and pathology.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20040301

• Effects of sarcoptic mange and its control with oil of Cedrus deodara, Pongamia glabra, Jatropha curcas and benzyl benzoate, both with and without ascorbic acid on growing sheep: assessment of weight gain, liver function, nutrient digestibility, wool production and meat quality.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20040301

• Isotropic medium chain mono-diglyceride/oil/water formulations for solubilization of lipophilic and hydrophilic drugs.

  International journal of pharmaceutics 20040211

• Inhibition of alpha-chymotrypsin with thiol-bearing substrate analogues in the presence of zinc ion.

  Bioorganic & medicinal chemistry letters 20040209

• Leaching of plasticizers from temporary denture soft lining materials.

  European journal of oral sciences 20040201

• The clinical effect of environmental control of house dust mites in 60 house dust mite-sensitive dogs.

  Veterinary dermatology 20040201

• Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier.

  Journal of controlled release : official journal of the Controlled Release Society 20040108

• Controlling scabies in institutional settings: a review of medications, treatment models, and implementation.

  American journal of clinical dermatology 20040101

• [Reconstruction of extensive soft tissue loss by transplantation of dermal and epidermal equivalents].

  Zentralblatt fur Chirurgie 20040101

• Rapid and sensitive quantitative analysis of alkyl phosphates in urine after organophosphate poisoning.

  Journal of analytical toxicology 20040101

• The efficacy of benzyl benzoate sprays in killing the storage mite Tyrophagus putrescentiae (Acari: Acaridae).

  Annals of agricultural and environmental medicine : AAEM 20040101

• 3 dimensional modelling of early human brain development using optical projection tomography.

  BMC neuroscience 20040101

• Erythema annulare centrifugum induced by generalized Phthirus pubis infestation.

  The British journal of dermatology 20031201

• Optimization of polylactic-co-glycolic acid nanoparticles containing itraconazole using 2(3) factorial design.

  AAPS PharmSciTech 20031201

• Freeze-drying polymeric colloidal suspensions: nanocapsules, nanospheres and nanodispersion. A comparative study.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20031101

• Identification and prediction of promiscuous aggregating inhibitors among known drugs.

  Journal of medicinal chemistry 20031009

• A trial to assess the efficacy and tolerability of Hyalofill-F in non-healing venous leg ulcers.

  Journal of wound care 20031001

• Cost-benefit analysis of ivermectin, permethrin and benzyl benzoate in the management of infantile and childhood scabies.

  Expert opinion on pharmacotherapy 20030901

• Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria.

  Journal of natural products 20030901

• Gland cell cultures into 3D hyaluronan-based scaffolds.

  Journal of materials science. Materials in medicine 20030801

• Structure formation in injectable poly(lactide-co-glycolide) depots.

  Journal of controlled release : official journal of the Controlled Release Society 20030731

• Estrogenic activity of tissue conditioners in vitro.

  Dental materials : official publication of the Academy of Dental Materials 20030601

• Molecular markers of anthropogenic activity in sediments of the Havel and Spree Rivers (Germany).

  Water research 20030601

• Quantitative fluorescence of 5-FU-treated fetal rat limbs using confocal laser scanning microscopy and Lysotracker Red.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030501

• Acaricidal activity of tonka bean extracts. Synthesis and structure-activity relationships of bioactive derivatives.

  Journal of natural products 20030501

• Current treatments for scabies.

  Fundamental & clinical pharmacology 20030401

• Acaricidal activity of Uvaria versicolor and Uvaria Klaineana (Annonaceae).

  Phytotherapy research : PTR 20030401

• Alternative solvents for elevated-temperature solid-phase parallel synthesis. Application to thionation of amides.

  Organic letters 20030306

• Pd/C-catalyzed chemoselective hydrogenation in the presence of a phenolic MPM protective group using pyridine as a catalyst poison.

  Chemical & pharmaceutical bulletin 20030301

• Acaricidal activity of clove bud oil compounds against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae).

  Journal of agricultural and food chemistry 20030212

• Understanding scabies.

  Nursing times 20030201

• Atovaquone-loaded nanocapsules: influence of the nature of the polymer on their in vitro characteristics.

  International journal of pharmaceutics 20030102

• Acaricidal activity of Cnidium officinale rhizome-derived butylidenephthalide against Tyrophagus putrescentiae (Acari: Acaridae).

  Pest management science 20030101

• Autologous human keratinocytes cultured on membranes composed of benzyl ester of hyaluronic acid for grafting in nonhealing diabetic foot lesions: a pilot study.

  Journal of diabetes and its complications 20030101

• Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors.

  The Journal of biological chemistry 20021115

• Diagnosis and treatment of scabies in 2002: rapid diagnosis and proper management limit the risk of spread.

  Prescrire international 20021001

• Characterization of an acyltransferase capable of synthesizing benzylbenzoate and other volatile esters in flowers and damaged leaves of Clarkia breweri.

  Plant physiology 20020901

• New microencapsulated sunscreens: technology and comparative evaluation.

  International journal of pharmaceutics 20020821

• Ivermectin is better than benzyl benzoate for childhood scabies in developing countries.

  Journal of paediatrics and child health 20020801

• Acaricidal activity of butylidenephthalide identified in Cnidium officinale rhizome against dermatophagoides farinae and dermatophagoides pteronyssinus (Acari: Pyroglyphidae).

  Journal of agricultural and food chemistry 20020731

• [Determination of volatile constituents in guanxin suhe wan by gas chromatography-mass spectrometry].

  Se pu = Chinese journal of chromatography 20020701

• Comparison of the antioxidant properties of HYAFF-11p75, AQUACEL and hyaluronan towards reactive oxygen species in vitro.

  Biomaterials 20020501

• Klaivanolide, an antiprotozoal lactone from Uvaria klaineana.

  Phytochemistry 20020401

• [Profuse scabies: kinetic curves of parasitologic cure with an association of benzyl benzoate and sulfiram].

  Annales de dermatologie et de venereologie 20020301

• Physico-chemical properties and degradability of non-woven hyaluronan benzylic esters as tissue engineering scaffolds.

  Biomaterials 20020201

• On the prodrug potential of novel aldose reductase inhibitors with diphenylmethyleneaminooxycarboxylic acid structure.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020201

• Placebo-controlled study of the mite allergen-reducing effect of tannic acid plus benzyl benzoate on carpets in homes of children with house dust mite sensitization and asthma.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20020201

• Bullous hematoma of the palm: an unusual complication of scabies in a child with congenital prothrombin deficiency.

  Pediatric dermatology 20020101

• [Stereochemistry of the reductive amination of 4-oxoproline derivatives with glycine esters].

  Bioorganicheskaia khimiia 20020101

• The use of ELM to monitor the success of antiscabietic treatment. Epiluminescence light microscopy.

  Archives of dermatology 20011201

• Long lasting antinociceptive properties of enkephalin degrading enzyme (NEP and APN) inhibitor prodrugs.

  Journal of medicinal chemistry 20011011

• Scabies presenting as a blistering eruption.

  Cutis 20011001

• 2-(Hydroxycarbonyl)benzyl glycosides: a novel type of glycosyl donors for highly efficient beta-mannopyranosylation and oligosaccharide synthesis by latent-active glycosylation.

  Journal of the American Chemical Society 20010905

• Functionalized oligoanthranilamides: modular and conformationally controlled scaffolds.

  Bioorganic & medicinal chemistry 20010901

• [Vascular purpura in a patient with severe sarcoptic acariasis].

  Annales de dermatologie et de venereologie 20010901

• Extensive traumatic soft tissue loss: reconstruction in severely injured patients using cultured hyaluronan-based three-dimensional dermal and epidermal autografts.

  The Journal of trauma 20010601

• [Scabies in a dalysis unit. Mystery and prejudice].

  Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20010601

• Fragrance volatiles of developing and senescing carnation flowers.

  Phytochemistry 20010401

• Biocompatibility and biodegradation of intravitreal hyaluronan implants in rabbits.

  Biomaterials 20010201

• Successful treatment of scabies with oral ivermectin in Nigeria.

  Tropical doctor 20010101

• Detection of estrogenicity by bioassay on the mouse mammary gland in vivo.

  Physiological research 20010101

• 2,6-Diketopiperazines from amino acids, from solution-phase to solid-phase organic synthesis.

  Journal of combinatorial chemistry 20010101

• Antineoplastic agents 460. Synthesis of combretastatin A-2 prodrugs.

  Anti-cancer drug design 20010101

• [Allergy to preservatives].

  Annales de dermatologie et de venereologie 19820101

• Convulsions following application of gamma benzene hexachloride.

  Journal of the American Academy of Dermatology 19810701