120-73-0 | Purine

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$9.00	$6.00
250mg	98%	in stock	$13.00	$9.00
1g	98%	in stock	$37.00	$26.00
25g	98%	in stock	$524.00	$367.00

Description

• Catalog Number: AA33556
• Chemical Name: Purine
• CAS Number: 120-73-0
• Molecular Formula: C5H4N4
• Molecular Weight: 120.1121
• MDL Number: MFCD00079221
• SMILES: c1ncc2c(n1)[nH]cn2
• NSC Number: 753

Computed Properties

• Complexity: 105
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: -0.4

Literature

• 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.

  Journal of medicinal chemistry 20150326

• 1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.

  Bioorganic & medicinal chemistry 20131201

• Anti-inflammatory effects of purine nucleosides, adenosine and inosine, in a mouse model of pleurisy: evidence for the role of adenosine A2 receptors.

  Purinergic signalling 20121201

• Effects of catalase and 1400W on the number of interleukin-4 and interferon-γ secreting spleen cells in mice injected with ovalbumin and alum.

  Immunopharmacology and immunotoxicology 20121201

• Retreatment with purine analogs in patients with chronic lymphocytic leukemia.

  Leukemia research 20121201

• S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin.

  Leukemia research 20121201

• The evolution of catalytic residues and enzyme mechanism within the bacterial nucleoside phosphorylase superfamily 1.

  Gene 20121201

• The investigation of the binding of 6-mercaptopurine to site I on human serum albumin.

  The protein journal 20121201

• Investigations into specificity of azepinomycin for inhibition of guanase: discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues.

  Bioorganic & medicinal chemistry letters 20121201

• Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.

  Bioorganic & medicinal chemistry 20121115

• Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state.

  Bioorganic & medicinal chemistry 20121115

• Synthesis of 6-amino-2-vinylpurine derivatives for cross-linking and evaluation of the reactivity.

  Bioorganic & medicinal chemistry letters 20121115

• Poly(alizarin red)/graphene modified glassy carbon electrode for simultaneous determination of purine and pyrimidine.

  Analytica chimica acta 20121108

• Structural basis of substrate specificity and selectivity of murine cytosolic 5'-nucleotidase III.

  Journal of molecular biology 20121102

• Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia.

  International journal of cancer 20121101

• Astrocyte origin of activity-dependent release of ATP and glutamate in hippocampal slices: real-time measurement utilizing microelectrode biosensors.

  British journal of pharmacology 20121101

• Synergism between clofarabine and decitabine through p53R2: a pharmacodynamic drug-drug interaction modeling.

  Leukemia research 20121101

• A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation.

  Mutagenesis 20121101

• Metabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout.

  Molecular bioSystems 20121101

• Quantitation of intracellular purine intermediates in different Corynebacteria using electrospray LC-MS/MS.

  Analytical and bioanalytical chemistry 20121101

• Pharmacokinetic evaluation and therapeutic activity of bendamustine in B-cell lymphoid malignancies.

  Expert opinion on drug metabolism & toxicology 20121101

• A perspective on diet and gout.

  Advances in chronic kidney disease 20121101

• Genetic disorders resulting in hyper- or hypouricemia.

  Advances in chronic kidney disease 20121101

• The rheumatology of gout.

  Advances in chronic kidney disease 20121101

• Advanced kidney failure and hyperuricemia.

  Advances in chronic kidney disease 20121101

• Fatty acids change the conformation of uncoupling protein 1 (UCP1).

  The Journal of biological chemistry 20121026

• Mild hyperhomocysteinemia alters extracellular adenine metabolism in rat brain.

  Neuroscience 20121025

• Effect of ginseng polysaccharide on the urinary excretion of type 2 diabetic rats studied by liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121015

• General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.

  Journal of the American Chemical Society 20121010

• Serum metabolomics in a Helicobacter hepaticus mouse model of inflammatory bowel disease reveal important changes in the microbiome, serum peptides, and intermediary metabolism.

  Journal of proteome research 20121005

• Dynamics and efficiency of hole transport in LNA:DNA hybrid diblock oligomers.

  Journal of the American Chemical Society 20121003

• An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-βT).

  Organic & biomolecular chemistry 20121003

• Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20121001

• Reduced serum uric acid levels in neuromyelitis optica: serum uric acid levels are reduced during relapses in NMO.

  Acta neurologica Scandinavica 20121001

• Reactions of benzene oxide, a reactive metabolite of benzene, with model nucleophiles and DNA.

  Xenobiotica; the fate of foreign compounds in biological systems 20121001

• Effect of roughage to concentrate ratio of sweet sorghum (Sorghum biclor L. Moench) bagasse-based complete diet on nutrient utilization and microbial N supply in lambs.

  Tropical animal health and production 20121001

• Genotype frequencies of drug-metabolizing enzymes responsible for purine and pyrimidine antagonists in a healthy Asian-Indian population.

  Biochemical genetics 20121001

• Developmental lead effects on behavior and brain gene expression in male and female BALB/cAnNTac mice.

  Neurotoxicology 20121001

• Modulation of lymphocyte function in vivo via inhibition of calcineurin or purine synthesis in patients with atopic dermatitis.

  The Journal of investigative dermatology 20121001

• Protection of dopaminergic cells by urate requires its accumulation in astrocytes.

  Journal of neurochemistry 20121001

• Tautomeric purine forms of 2-amino-6-chloropurine (N9H10 and N7H10): structures, vibrational assignments, NBO analysis, hyperpolarizability, HOMO-LUMO study using B3 based density functional calculations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• A(₂B)AR expression in non-immune cells plays an important role in the development of murine colitis.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20121001

• Hydroxynonenal, a lipid peroxidation end product, stimulates uncoupling protein activity in Acanthamoeba castellanii mitochondria; the sensitivity of the inducible activity to purine nucleotides depends on the membranous ubiquinone redox state.

  Journal of bioenergetics and biomembranes 20121001

• Structural and kinetic studies of Schistosoma mansoni adenylate kinases.

  Molecular and biochemical parasitology 20121001

• MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration.

  The American journal of pathology 20121001

• Purine anti-metabolite attenuates nuclear factor κB and related pro-inflammatory cytokines in experimental vasospasm.

  Acta neurochirurgica 20121001

• Purinergic signaling in the airways.

  Pharmacological reviews 20121001

• The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy.

  RNA (New York, N.Y.) 20121001

• Nutrient utilization, ruminal fermentation, microbial abundances, and milk yield and composition in dairy goats fed diets including tomato and cucumber waste fruits.

  Journal of dairy science 20121001

• Discovery of 6-[4-(6-nitroxyhexanoyl)piperazin-1-yl)]-9H-purine, as pharmacological post-conditioning agent.

  Bioorganic & medicinal chemistry 20121001

• Neuronal and extraneuronal release of ATP and NAD(+) in smooth muscle.

  IUBMB life 20121001

• Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols.

  Bioorganic & medicinal chemistry 20121001

• Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids.

  Biochimica et biophysica acta 20121001

• Lack of expression of MTAP in uncommon T-cell lymphomas.

  Clinical lymphoma, myeloma & leukemia 20121001

• GC-TOF-MS- and CE-TOF-MS-based metabolic profiling of cheonggukjang (fast-fermented bean paste) during fermentation and its correlation with metabolic pathways.

  Journal of agricultural and food chemistry 20120926

• Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase.

  Chembiochem : a European journal of chemical biology 20120924

• Simultaneous analysis of the main markers of nitrogen status in dairy cow's urine using hydrophilic interaction chromatography and tandem mass spectrometry detection.

  Journal of chromatography. A 20120921

• H-bonds superstructures built by aquacomplexes and an azapurine derivative: a case of molecular recognition.

  Dalton transactions (Cambridge, England : 2003) 20120914

• Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor.

  Journal of medicinal chemistry 20120913

• Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity.

  Molecules (Basel, Switzerland) 20120912

• Photosensitizing properties of biopterin and its photoproducts using 2'-deoxyguanosine 5'-monophosphate as an oxidizable target.

  Physical chemistry chemical physics : PCCP 20120907

• Fludarabine and cladribine induce changes in surface proteins on human B-lymphoid cell lines involved with apoptosis, cell survival, and antitumor immunity.

  Journal of proteome research 20120907

• A stereoselective approach to β-L-arabino nucleoside analogues: synthesis and cyclization of acyclic 1',2'-syn N,O-acetals.

  The Journal of organic chemistry 20120907

• Copper-catalyzed synthesis of purine-fused polycyclics.

  Organic letters 20120907

• Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides.

  European journal of pharmacology 20120905

• Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment.

  Medical oncology (Northwood, London, England) 20120901

• Purines as potential morphogens during embryonic development.

  Purinergic signalling 20120901

• Clofarabine in pediatric acute leukemia: current findings and issues.

  Pediatric blood & cancer 20120901

• G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions.

  Purinergic signalling 20120901

• Carbocyclic thymidine derivatives efficiently inhibit Plasmodium falciparum thymidylate kinase (PfTMK).

  Parasitology international 20120901

• Preliminary evidence for the dedifferentiation of RAW 264.7 cells into mesenchymal progenitor-like cells by a purine analog.

  Tissue engineering. Part A 20120901

• Molecular and functional properties of P2X receptors--recent progress and persisting challenges.

  Purinergic signalling 20120901

• Purine-rich foods intake and recurrent gout attacks.

  Annals of the rheumatic diseases 20120901

• Medical therapy and mucosal healing.

  Current drug targets 20120901

• Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity.

  The Biochemical journal 20120901

• Functional characterization of UCP1 in mammalian HEK293 cells excludes mitochondrial uncoupling artefacts and reveals no contribution to basal proton leak.

  Biochimica et biophysica acta 20120901

• Graft-versus-host disease reduces regulatory T-cell migration into the tumour tissue.

  Immunology 20120901

• Gene expression profile of early in vitro biofilms of Streptococcus pneumoniae.

  Microbiology and immunology 20120901

• Successful treatment with azathioprine of relapsing Rosai-Dorfman disease of the central nervous system.

  Journal of neurosurgery 20120901

• Mycophenolate mofetil inhibits hepatitis C virus replication in human hepatic cells.

  Virus research 20120901

• Gene expression profiles of vitrified in vitro- and in vivo-derived bovine blastocysts.

  Molecular reproduction and development 20120901

• Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells.

  Cancer biology & therapy 20120901

• Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.

  Bioorganic & medicinal chemistry 20120901

• Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities.

  DNA repair 20120901

• Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.

  Autophagy 20120901

• Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120901

• Smart portable electrophoresis instrument based on multipurpose microfluidic chips with electrochemical detection.

  Electrophoresis 20120901

• Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulence.

  PLoS genetics 20120901

• 2-Chloro-N-ethyl-9-isopropyl-9H-purin-6-amine.

  Acta crystallographica. Section E, Structure reports online 20120901

• Significance of mycophenolate monitoring in liver transplant recipients: toward the cut-off level.

  Transplantation proceedings 20120901

• Extent of intramolecular π-stacks in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and several 2-aminopurine derivatives of the antivirally active nucleotide analog 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).

  Chemistry & biodiversity 20120901

• Leishmania metacyclogenesis is promoted in the absence of purines.

  PLoS neglected tropical diseases 20120901

• Click fleximers: a modular approach to purine base-expanded ribonucleoside analogues.

  Organic & biomolecular chemistry 20120828

• 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove.

  Organic & biomolecular chemistry 20120828

• Inhibition of pokeweed antiviral protein (PAP) by turnip mosaic virus genome-linked protein (VPg).

  The Journal of biological chemistry 20120824

• Multicomponent assembly of proposed DNA precursors in water.

  Journal of the American Chemical Society 20120822

• Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation.

  Biochemistry 20120821

• Low-level lead exposure and the prevalence of gout: an observational study.

  Annals of internal medicine 20120821

• Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses.

  American journal of physiology. Renal physiology 20120815

• Haplotypes across the human caveolin 1 gene upstream purine complex significantly alter gene expression: implication in neurodegenerative disorders.

  Gene 20120815

• Identification and dynamic analysis of the purine alkaloids in rat plasma after oral administration of green tea by liquid chromatography hybrid ion trap time-of-flight mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120815

• Metabolic labeling of DNA by purine analogues in vivo.

  Chembiochem : a European journal of chemical biology 20120813

• Surface-enhanced Raman scattering of whole human blood, blood plasma, and red blood cells: cellular processes and bioanalytical sensing.

  The journal of physical chemistry. B 20120809

• Analysis of urinary metabolic signatures of early hepatocellular carcinoma recurrence after surgical removal using gas chromatography-mass spectrometry.

  Journal of proteome research 20120803

• The effect of depurinized milk draught diet on rat serum uric acid, lipid status and haematological parameters.

  Journal of animal physiology and animal nutrition 20120801

• Role of the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension.

  Prostaglandins & other lipid mediators 20120801

• Density functional study on the derivatives of purine.

  Journal of molecular modeling 20120801

• Tumor metabolism as modulator of immune response and tumor progression.

  Seminars in cancer biology 20120801

• Cerebellar abnormalities in purine nucleoside phosphorylase deficient mice.

  Neurobiology of disease 20120801

• Genetic damage induced by organic extract of coke oven emissions on human bronchial epithelial cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20120801

• Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.

  Proteins 20120801

• Predictive factors for poor peripheral blood stem cell mobilization and peak CD34(+) cell count to guide pre-emptive or immediate rescue mobilization.

  Cytotherapy 20120801

• Hepatic hemodynamics in 24 patients with nodular regenerative hyperplasia and symptomatic portal hypertension.

  Journal of gastroenterology and hepatology 20120801

• C-C cross-coupling reactions of O6-alkyl-2-haloinosine derivatives and a one-pot cross-coupling/O6-deprotection procedure.

  Chemistry, an Asian journal 20120801

• T- and B-cell defects in a novel purine nucleoside phosphorylase mutation.

  The Journal of allergy and clinical immunology 20120801

• Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors.

  Pharmacology, biochemistry, and behavior 20120801

• Urate in Parkinson's disease: more than a biomarker?

  Current neurology and neuroscience reports 20120801

• Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferases.

  Protein science : a publication of the Protein Society 20120801

• Regioselective enzymatic undecylenoylation of 8-chloroadenosine and its analogs with biomass-based 2-methyltetrahydrofuran as solvent.

  Bioresource technology 20120801

• Unraveling ultrafast dynamics in photoexcited aniline.

  Journal of the American Chemical Society 20120801

• Purine salvage in Leishmania: complex or simple by design?

  Trends in parasitology 20120801

• Remodeling of cytokinin metabolism at infection sites of Colletotrichum graminicola on maize leaves.

  Molecular plant-microbe interactions : MPMI 20120801

• Discovery and optimization of novel purines as potent and selective CB2 agonists.

  Bioorganic & medicinal chemistry letters 20120801

• Lesch-Nyhan syndrome: mRNA expression of HPRT in patients with enzyme proven deficiency of HPRT and normal HPRT coding region of the DNA.

  Molecular genetics and metabolism 20120801

• Assaying the proton transport and regulation of UCP1 using solid supported membranes.

  European biophysics journal : EBJ 20120801

• Structure and mechanism of purine-binding riboswitches.

  Quarterly reviews of biophysics 20120801

• Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines.

  Molecular diversity 20120801

• Molecular analysis of mutants of the Neurospora adenylosuccinate synthetase locus.

  Journal of genetics 20120801

• Continuous enzyme-coupled assay of phosphate- or pyrophosphate-releasing enzymes.

  BioTechniques 20120801

• The pendulum model for genome compositional dynamics: from the four nucleotides to the twenty amino acids.

  Genomics, proteomics & bioinformatics 20120801

• Strand-biased gene distribution in bacteria is related to both horizontal gene transfer and strand-biased nucleotide composition.

  Genomics, proteomics & bioinformatics 20120801

• Catalytic zinc site and mechanism of the metalloenzyme PR-AMP cyclohydrolase.

  Biochemistry 20120724

• The mechanism of guanine alkylation by nitrogen mustards: a computational study.

  The Journal of organic chemistry 20120720

• A dramatic concentration effect on the stereoselectivity of N-glycosylation for the synthesis of 2'-deoxy-β-ribonucleosides.

  Chemical communications (Cambridge, England) 20120718

• The electronic spectra and the H-bonding pattern of the sulfur and selenium substituted guanines.

  Journal of computational chemistry 20120715

• Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors.

  Bioorganic & medicinal chemistry letters 20120715

• Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: a multicenter, randomized phase III study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120710

• Molecular biology of pancreatic cancer: how useful is it in clinical practice?

  JOP : Journal of the pancreas 20120710

• Nafion-CNT coated carbon-fiber microelectrodes for enhanced detection of adenosine.

  The Analyst 20120707

• Synthetic control of framework zinc purinate crystallisation and properties of a large pore, decorated, mixed-linker RHO-type ZIF.

  Chemical communications (Cambridge, England) 20120707

• Purinergic signaling promotes proliferation of adult mouse subventricular zone cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120704

• Novel features in the evolution of adenylosuccinate lyase deficiency.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120701

• Adenosine deaminase activity in serum and lymphocytes of rats infected with Sporothrix schenckii.

  Mycopathologia 20120701

• One-step enzymatic synthesis of nucleosides from low water-soluble purine bases in non-conventional media.

  Bioresource technology 20120701

• The inhibitors of nucleotide biosynthesis leflunomide, FK778, and mycophenolic acid activate hepatitis B virus replication in vitro.

  Hepatology (Baltimore, Md.) 20120701

• Oxidatively generated DNA lesions as potential biomarkers of in vivo oxidative stress.

  Current molecular medicine 20120701

• Methylation capacity in children with severe cerebral palsy.

  European journal of clinical investigation 20120701

• Enzymology of tRNA modification in the bacterial MnmEG pathway.

  Biochimie 20120701

• The role of the NTPDase enzyme family in parasites: what do we know, and where to from here?

  Parasitology 20120701

• Reversine, a 2,6-disubstituted purine, as an anti-cancer agent in differentiated and undifferentiated thyroid cancer cells.

  Pharmaceutical research 20120701

• Phosphorylation of deoxycytidine kinase on Ser-74: impact on kinetic properties and nucleoside analog activation in cancer cells.

  Biochemical pharmacology 20120701

• Next-generation sequencing offers new insights into DNA degradation.

  Trends in biotechnology 20120701

• Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.

  Bioorganic & medicinal chemistry letters 20120701

• Defining combined immunodeficiency.

  The Journal of allergy and clinical immunology 20120701

• 8-17 DNAzyme modified with purine analogs in its catalytic core: the conservation of the five-membered moieties of purine residues.

  Bioorganic & medicinal chemistry letters 20120701

• Effect of incremental flaxseed supplementation of an herbage diet on methane output and ruminal fermentation in continuous culture.

  Journal of dairy science 20120701

• Motor neurone disease in molybdenum-deficient sheep fed the endogenous purine xanthosine: possible mechanism for Tribulus staggers.

  Australian veterinary journal 20120701

• DNA triplex structures in neurodegenerative disorder, Friedreich's ataxia.

  Journal of biosciences 20120701

• Adult T-cell leukemia/lymphoma.

  The Gulf journal of oncology 20120701

• Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.

  Aging 20120701

• Nucleoside transporters: biological insights and therapeutic applications.

  Future medicinal chemistry 20120701

• [The first case of adenine phosphoribosyltransferase deficiency with APRT*Q0 (M1I) mutation in Japan].

  Hinyokika kiyo. Acta urologica Japonica 20120701

• Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.

  Chemistry & biology 20120622

• Fluorescent C-linked C8-aryl-guanine probe for distinguishing syn from anti structures in duplex DNA.

  Chemical research in toxicology 20120618

• Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20120615

• Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors.

  Bioorganic & medicinal chemistry letters 20120615

• Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides.

  Bioorganic & medicinal chemistry 20120615

• X-ray spectroscopy of heterocyclic biochemicals: xanthine, hypoxanthine, and caffeine.

  The journal of physical chemistry. A 20120614

• Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates.

  Journal of the American Chemical Society 20120613

• Structure-activity relationship of a cold-adapted purine nucleoside phosphorylase by site-directed mutagenesis.

  Enzyme and microbial technology 20120610

• New determinants in the catalytic mechanism of nucleoside hydrolases from the structures of two isozymes from Sulfolobus solfataricus.

  Biochemistry 20120605

• Transcriptional profile of GTP-mediated differentiation of C2C12 skeletal muscle cells.

  Purinergic signalling 20120601

• Spectrum of neurologic complications in chronic lymphocytic leukemia.

  Clinical lymphoma, myeloma & leukemia 20120601

• Non-infectious lung disease in patients with adenosine deaminase deficient severe combined immunodeficiency.

  Journal of clinical immunology 20120601

• An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects.

  Human molecular genetics 20120601

• Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer.

  International journal of oncology 20120601

• Novel and emerging drugs for rarer chronic lymphoid leukaemias.

  Current cancer drug targets 20120601

• Novel and emerging drugs for acute lymphoblastic leukemia.

  Current cancer drug targets 20120601

• Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.

  Therapeutic drug monitoring 20120601

• The second sodium pump: from the function to the gene.

  Pflugers Archiv : European journal of physiology 20120601

• Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study.

  RNA (New York, N.Y.) 20120601

• Facially-selective thymine-thymine photodimerization in TTT triads.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601

• Effects of long-term experimental diabetes on adrenal gland growth and phosphoribosyl pyrophosphate formation in growth hormone-deficient dwarf rats.

  International journal of experimental pathology 20120601

• Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy.

  The Journal of clinical investigation 20120601

• Usefulness of material recovered from distal embolic protection devices after carotid angioplasty for proteomic studies.

  Journal of vascular and interventional radiology : JVIR 20120601

• Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling.

  Acta crystallographica. Section D, Biological crystallography 20120601

• A model for 3-methyladenine recognition by 3-methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120601

• Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae.

  PLoS genetics 20120601

• Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement.

  PLoS genetics 20120601

• Gram-scale chemical synthesis of 2'-deoxynucleoside-5'-o-triphosphates.

  Current protocols in nucleic acid chemistry 20120601

• Caffeine-N-phthaloyl-β-alanine (1/1).

  Acta crystallographica. Section E, Structure reports online 20120601

• Application of a fluorescent C-linked phenolic purine adduct for selective N7-metalation of DNA.

  The journal of physical chemistry. B 20120531

• Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana.

  The Journal of biological chemistry 20120525

• A unified mechanism for abiotic adenine and purine synthesis in formamide.

  Angewandte Chemie (International ed. in English) 20120521

• The CDK9 C-helix exhibits conformational plasticity that may explain the selectivity of CAN508.

  ACS chemical biology 20120518

• Design and divergent synthesis of aza nucleosides from a chiral imino sugar.

  The Journal of organic chemistry 20120518

• Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative.

  Biochemical pharmacology 20120515

• Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5.

  Biochemistry 20120515

• On the accessibility to conical intersections in purines: hypoxanthine and its singly protonated and deprotonated forms.

  Journal of the American Chemical Society 20120509

• Genetic and molecular characterization reveals a unique nucleobase cation symporter 1 in Arabidopsis.

  FEBS letters 20120507

• Total synthesis of a cyclic adenosine 5'-diphosphate ribose receptor agonist.

  The Journal of organic chemistry 20120504

• Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1.

  AIDS research and human retroviruses 20120501

• Effects of P2Y(1) receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel.

  British journal of pharmacology 20120501

• Riboswitch structure in the ligand-free state.

  Wiley interdisciplinary reviews. RNA 20120501

• Yield of single- and double-strand breaks and nucleobase lesions in fully hydrated plasmid DNA films irradiated with high-LET charged particles.

  Radiation research 20120501

• Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors.

  Naunyn-Schmiedeberg's archives of pharmacology 20120501

• Initial experience with bendamustine in patients with recurrent primary central nervous system lymphoma: a case report.

  Journal of neuro-oncology 20120501

• Development and mapping of SNP assays in allotetraploid cotton.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20120501

• Differential response of Drosophila cell lines to extracellular adenosine.

  Insect biochemistry and molecular biology 20120501

• Purine nucleosides: endogenous neuroprotectants in hypoxic brain.

  Journal of neurochemistry 20120501

• The soluble proteome of tobacco Bright Yellow-2 cells undergoing H₂O₂-induced programmed cell death.

  Journal of experimental botany 20120501

• Confocal Raman microspectroscopic study of folate receptor-targeted delivery of 6-mercaptopurine-embedded gold nanoparticles in a single cell.

  Journal of biomedical materials research. Part A 20120501

• Functional analysis of the relative growth rate, chemical composition, construction and maintenance costs, and the payback time of Coffea arabica L. leaves in response to light and water availability.

  Journal of experimental botany 20120501

• Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications.

  Journal of cardiology 20120501

• Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?

  Ecotoxicology (London, England) 20120501

• Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues.

  Bioorganic & medicinal chemistry 20120501

• The adenosine deaminases of Plasmodium vivax and Plasmodium falciparum exhibit surprising differences in ligand specificity.

  Journal of molecular graphics & modelling 20120501

• Prolonged fasting increases purine recycling in post-weaned northern elephant seals.

  The Journal of experimental biology 20120501

• Purine biosynthesis mutants (purA and purB) of serotype 4b Listeria monocytogenes are severely attenuated for systemic infection in intragastrically inoculated A/J Mice.

  Foodborne pathogens and disease 20120501

• Waldenström macroglobulinemia: 2012 update on diagnosis, risk stratification, and management.

  American journal of hematology 20120501

• Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei.

  PLoS neglected tropical diseases 20120501

• NIBBS-search for fast and accurate prediction of phenotype-biased metabolic systems.

  PLoS computational biology 20120501

• 3-(2,4-Dichloro-phen-yl)-5-(4-fluoro-phen-yl)-2-methyl-7-(trifluoro-meth-yl)pyrazolo-[1,5-a]pyrimidine.

  Acta crystallographica. Section E, Structure reports online 20120501

• Variability of gemcitabine accumulation and its relationship to expression of nucleoside transporters in peripheral blood mononuclear cells.

  Archives of pharmacal research 20120501

• Treatment of hairy cell leukemia: long-term results in a developing country.

  Hematology (Amsterdam, Netherlands) 20120501

• New and Redesigned pRS Plasmid Shuttle Vectors for Genetic Manipulation of Saccharomycescerevisiae.

  G3 (Bethesda, Md.) 20120501

• The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes.

  PLoS computational biology 20120501

• Mechanisms of Platelet Activation and Integrin αIIβ3.

  Korean circulation journal 20120501

• A cyclodextrin host-guest recognition approach to a label-free electrochemical DNA hybridization biosensor.

  The Analyst 20120421

• Effect of the H-bonding on aromaticity of purine tautomers.

  The Journal of organic chemistry 20120420

• Lower serum UA levels in Parkinson's disease patients in the Chinese population.

  Neuroscience letters 20120418

• The formamidopyrimidines: purine lesions formed in competition with 8-oxopurines from oxidative stress.

  Accounts of chemical research 20120417

• Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+).

  The Journal of physiology 20120415

• P2Y1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit.

  The Journal of physiology 20120415

• 2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.

  Bioorganic & medicinal chemistry letters 20120415

• Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(β-D-ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells.

  Journal of medicinal chemistry 20120412

• Does the growth temperature of a prokaryote influence the purine content of its mRNAs?

  Gene 20120410

• Capillary bioreactors based on human purine nucleoside phosphorylase: a new approach for ligands identification and characterization.

  Journal of chromatography. A 20120406

• Synthesis and properties of 5-cyano-substituted nucleoside analog with a donor-donor-acceptor hydrogen-bonding pattern.

  The Journal of organic chemistry 20120406

• New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A.

  FEBS letters 20120405

• Decreased extra-renal urate excretion is a common cause of hyperuricemia.

  Nature communications 20120403

• Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics.

  The pharmacogenomics journal 20120401

• Mantle cell lymphoma.

  Critical reviews in oncology/hematology 20120401

• A comparative study on mimosine, 3,4-dihydroxy pyridone (3,4-DHP) and 2,3-dihydroxy pyridone (2,3-DHP), purine derivatives (PD) excretion in the urine, thyroid hormone and blood metabolites profiles of Thai swamp buffalo (Bubalus bubalis) and Murrah buffalo (Bubalus bubalis).

  Tropical animal health and production 20120401

• Elevated uric acid correlates with wound severity.

  International wound journal 20120401

• A spicamycin derivative (KRN5500) provides neuropathic pain relief in patients with advanced cancer: a placebo-controlled, proof-of-concept trial.

  Journal of pain and symptom management 20120401

• Uric acid excretion in healthy subjects: a nomogram to assess the mechanisms underlying purine metabolic disorders.

  Metabolism: clinical and experimental 20120401

• Comparative genomics of Bifidobacterium, Lactobacillus and related probiotic genera.

  Microbial ecology 20120401

• Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors.

  Molecular biology reports 20120401

• CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120401

• Protection of riboflavin and UVB sensitized degradation of DNA and RNA bases by natural antioxidants.

  Ecotoxicology and environmental safety 20120401

• Domain III regulates N-type (CaV2.2) calcium channel closing kinetics.

  Journal of neurophysiology 20120401

• Glial-derived adenosine modulates spinal motor networks in mice.

  Journal of neurophysiology 20120401

• Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120401

• Vascular endothelial function is not related to serum uric acid in healthy adults.

  American journal of hypertension 20120401

• Transcriptome analysis of silver carp (Hypophthalmichthys molitrix) by paired-end RNA sequencing.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20120401

• Ingenuity pathways analysis of urine metabolomics phenotypes toxicity of Chuanwu in Wistar rats by UPLC-Q-TOF-HDMS coupled with pattern recognition methods.

  Molecular bioSystems 20120401

• Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells.

  Molecular medicine reports 20120401

• Electrochemically synthesized polymers in molecular imprinting for chemical sensing.

  Analytical and bioanalytical chemistry 20120401

• Programmed cell death induced by high levels of cytokinin in Arabidopsis cultured cells is mediated by the cytokinin receptor CRE1/AHK4.

  Journal of experimental botany 20120401

• Comparative modeling of HGPRT enzyme of L. donovani and binding affinities of different analogs of GMP.

  International journal of biological macromolecules 20120401

• Unveiling Mycoplasma hyopneumoniae promoters: sequence definition and genomic distribution.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20120401

• Novel metabolic aspects related to adenosine deaminase inhibition in a human astrocytoma cell line.

  Neurochemistry international 20120401

• The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates.

  Bioorganic & medicinal chemistry 20120401

• Regulation of neutrophil function by adenosine.

  Arteriosclerosis, thrombosis, and vascular biology 20120401

• Regulation of foam cells by adenosine.

  Arteriosclerosis, thrombosis, and vascular biology 20120401

• Long-range heteronuclear coupling constants in 2,6-disubstituted purine derivatives.

  Magnetic resonance in chemistry : MRC 20120401

• De novo pyrimidine nucleotide synthesis mainly occurs outside of plastids, but a previously undiscovered nucleobase importer provides substrates for the essential salvage pathway in Arabidopsis.

  The Plant cell 20120401

• Nicotine alters the ectonucleotidases activities in lymphocytes: In vitro and in vivo studies.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120401

• Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection.

  PLoS pathogens 20120401

• Improving treatment for patients with chronic lymphocytic leukemia.

  Hematology (Amsterdam, Netherlands) 20120401

• Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation.

  PLoS biology 20120401

• The transcription factor AmrZ utilizes multiple DNA binding modes to recognize activator and repressor sequences of Pseudomonas aeruginosa virulence genes.

  PLoS pathogens 20120401

• On-admission serum uric acid predicts outcomes after acute myocardial infarction: systematic review and meta-analysis of prognostic studies.

  Croatian medical journal 20120401

• Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism.

  BMB reports 20120401

• Development and validation of an improved algorithm for overlaying flexible molecules.

  Journal of computer-aided molecular design 20120401

• A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon.

  PLoS pathogens 20120401

• Diisopropyl {[(R)-2-(2-amino-6-chloro-9H-purin-9-yl)-1-methyl-eth-oxy]meth-yl}-phospho-nate.

  Acta crystallographica. Section E, Structure reports online 20120401

• First total synthesis of a naturally occurring iodinated 5'-deoxyxylofuranosyl marine nucleoside.

  Marine drugs 20120401

• Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.

  Oncogene 20120329

• Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.

  The Journal of biological chemistry 20120323

• A short story of anti-rheumatic therapy. VIII. The immunodepressants.

  Reumatismo 20120319

• Allostery and cooperativity in Escherichia coli aspartate transcarbamoylase.

  Archives of biochemistry and biophysics 20120315

• Role of myosin Va in purinergic vesicular neurotransmission in the gut.

  American journal of physiology. Gastrointestinal and liver physiology 20120315

• A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3).

  The Biochemical journal 20120315

• Cell signalling by reactive lipid species: new concepts and molecular mechanisms.

  The Biochemical journal 20120315

• HOMO energy gap dependence of hole-transfer kinetics in DNA.

  Journal of the American Chemical Society 20120314

• Deletion of ecto-5'-nucleotidase (CD73) reveals direct action potential-dependent adenosine release.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120314

• Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

  Journal of medicinal chemistry 20120308

• Binding affinity prediction for ligands and receptors forming tautomers and ionization species: inhibition of mitogen-activated protein kinase-activated protein kinase 2 (MK2).

  Journal of medicinal chemistry 20120308

• Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization.

  Organic & biomolecular chemistry 20120307

• Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.

  Cell metabolism 20120307

• Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism.

  The Journal of biological chemistry 20120302

• Proteomic pleiotropy of OpgGH, an operon necessary for efficient growth of Salmonella enterica serovar typhimurium under low-osmotic conditions.

  Journal of proteome research 20120302

• Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

  Journal of cardiovascular pharmacology and therapeutics 20120301

• Proposed definition of 'poor mobilizer' in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo Osseo.

  Bone marrow transplantation 20120301

• Simultaneous determination of metacavir and its metabolites in rat plasma using high-performance liquid chromatography with tandem mass spectrometric detection (LC-MS/MS).

  Biomedical chromatography : BMC 20120301

• A phase I study in adults of clofarabine combined with high-dose melphalan as reduced-intensity conditioning for allogeneic transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120301

• Post-remission intervention with alemtuzumab or rituximab to eradicate minimal residual disease in chronic lymphocytic leukemia: where do we stand?

  Leukemia & lymphoma 20120301

• Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats.

  The British journal of nutrition 20120301

• Effects of 3 weeks GMP oral administration on glutamatergic parameters in mice neocortex.

  Purinergic signalling 20120301

• Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3.

  Purinergic signalling 20120301

• Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production.

  Applied microbiology and biotechnology 20120301

• Systematic review of purine analog treatment for chronic lymphocytic leukemia: lessons for future trials.

  Haematologica 20120301

• Fludarabine and rituximab for relapsed or refractory hairy cell leukemia.

  Blood 20120301

• Identification of Rv0535 as methylthioadenosine phosphorylase from Mycobacterium tuberculosis.

  Tuberculosis (Edinburgh, Scotland) 20120301

• Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20120301

• Back to the future: lessons learned in modern target-based and whole-cell lead optimization of antimalarials.

  Current topics in medicinal chemistry 20120301

• The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.

  RNA (New York, N.Y.) 20120301

• Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix.

  Bioorganic & medicinal chemistry letters 20120301

• Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.

  Acta crystallographica. Section D, Biological crystallography 20120301

• A corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase II.

  Acta crystallographica. Section D, Biological crystallography 20120301

• Dual diagnosis of dihydropyrimidine dehydrogenase deficiency and GM₁ gangliosidosis.

  Pediatric neurology 20120301

• C6-substituted purine derivatives: an experimental and theoretical 1H, 13C and 15N NMR study.

  Magnetic resonance in chemistry : MRC 20120301

• Feasibility of non-TBI conditioning with busulfan and fludarabine for allogeneic stem cell transplantation in lymphoid malignancy.

  The Korean journal of internal medicine 20120301

• Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming.

  PLoS pathogens 20120301

• The impact of oxygen on metabolic evolution: a chemoinformatic investigation.

  PLoS computational biology 20120301

• Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum.

  Current drug metabolism 20120301

• Broad-specificity mRNA-rRNA complementarity in efficient protein translation.

  PLoS genetics 20120301

• Anti-obesity and anti-diabetic effects of Yerba Mate (Ilex paraguariensis) in C57BL/6J mice fed a high-fat diet.

  Laboratory animal research 20120301

• [Measurement of purines and uric acid simultaneous in meat with high performance liquid chromatographys].

  Wei sheng yan jiu = Journal of hygiene research 20120301

• Initiation of 8-oxoguanine base excision repair within trinucleotide tandem repeats.

  Biochemistry. Biokhimiia 20120301

• Probing transient Hoogsteen hydrogen bonds in canonical duplex DNA using NMR relaxation dispersion and single-atom substitution.

  Journal of the American Chemical Society 20120227

• Allopurinol acutely increases adenosine triphospate energy delivery in failing human hearts.

  Journal of the American College of Cardiology 20120227

• A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH.

  Biochemical and biophysical research communications 20120224

• Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier.

  Journal of medicinal chemistry 20120223

• Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A.

  Journal of medicinal chemistry 20120223

• Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.

  Journal of medicinal chemistry 20120223

• N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.

  Journal of medicinal chemistry 20120223

• The influence of homocysteine and oxidative stress on pregnancy outcome.

  Journal of medicine and life 20120222

• Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo.

  Chemical research in toxicology 20120220

• Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT.

  Chemical research in toxicology 20120220

• Proteomic analysis of hemoglobin H-constant spring (Hb H-CS) erythroblasts.

  Blood cells, molecules & diseases 20120215

• Base pairing at the abasic site in DNA duplexes and its application in adenosine aptasensors.

  Chembiochem : a European journal of chemical biology 20120213

• Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.

  Blood 20120209

• Change in tea polyphenol and purine alkaloid composition during solid-state fungal fermentation of postfermented tea.

  Journal of agricultural and food chemistry 20120208

• Platinum-modified adenines: unprecedented protonation behavior revealed by NMR spectroscopy and relativistic density-functional theory calculations.

  Inorganic chemistry 20120206

• Proteome of the early embryo-maternal dialogue in the cattle uterus.

  Journal of proteome research 20120203

• Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.

  The Journal of biological chemistry 20120203

• Proton transfers along hydrogen bonds in the tautomerization of purine.

  The journal of physical chemistry. A 20120202

• Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies.

  Clinical and experimental nephrology 20120201

• Primary immunodeficiency diseases associated with neurologic manifestations.

  Journal of clinical immunology 20120201

• MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease?

  Human molecular genetics 20120201

• DNA glycosylases: in DNA repair and beyond.

  Chromosoma 20120201

• Partial adenosine A1 receptor agonists for cardiovascular therapies.

  Purinergic signalling 20120201

• Gene expression profile in response to doxorubicin-rapamycin combined treatment of HER-2-overexpressing human mammary epithelial cell lines.

  Molecular cancer therapeutics 20120201

• Using antibodies against P2Y and P2X receptors in purinergic signaling research.

  Purinergic signalling 20120201

• Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivation.

  The Journal of pharmacology and experimental therapeutics 20120201

• Measurement of purine release with microelectrode biosensors.

  Purinergic signalling 20120201

• Inhibitors of membranous adenylyl cyclases.

  Trends in pharmacological sciences 20120201

• The crystal structure of Leishmania major N(5),N(10)-methylenetetrahydrofolate dehydrogenase/cyclohydrolase and assessment of a potential drug target.

  Molecular and biochemical parasitology 20120201

• Biomass production of site selective 13C/15N nucleotides using wild type and a transketolase E. coli mutant for labeling RNA for high resolution NMR.

  Journal of biomolecular NMR 20120201

• Training-induced adaptation in purine metabolism in high-level sprinters vs. triathletes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20120201

• A continuous spectrophotometric assay for mitogen-activated protein kinase kinases.

  Analytical biochemistry 20120201

• Natural product DNA major groove binders.

  Natural product reports 20120201

• Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.

  Bioorganic & medicinal chemistry 20120201

• Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis.

  Journal of Crohn's & colitis 20120201

• Construction and completion of flux balance models from pathway databases.

  Bioinformatics (Oxford, England) 20120201

• Is bendamustine an ideal partner for rituximab in the management of relapsed chronic lymphocytic leukemia? Results of a multicenter Phase II trial.

  Expert review of hematology 20120201

• Simultaneous determination of polyphenols and major purine alkaloids in Greek Sideritis species, herbal extracts, green tea, black tea, and coffee by high-performance liquid chromatography-diode array detection.

  Journal of separation science 20120201

• Positive evolutionary selection of an HD motif on Alzheimer precursor protein orthologues suggests a functional role.

  PLoS computational biology 20120201

• Ethyl 1-(2-hy-droxy-eth-yl)-2-(4-meth-oxy-phen-yl)-1H-benzimidazole-5-carboxyl-ate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20120201

• Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice.

  Nutrition research (New York, N.Y.) 20120201

• Polymorphisms in 1-carbon metabolism, epigenetics and folate-related pathologies.

  Journal of nutrigenetics and nutrigenomics 20120201

• Dynamic energy landscapes of riboswitches help interpret conformational rearrangements and function.

  PLoS computational biology 20120201

• Clear genetic distinctiveness between human- and pig-derived Trichuris based on analyses of mitochondrial datasets.

  PLoS neglected tropical diseases 20120201

• Comparison of insertional RNA editing in Myxomycetes.

  PLoS computational biology 20120201

• Clinical features and long term outcome of 102 treated autoimmune hepatitis patients.

  Hepatitis monthly 20120201

• [Hepatotoxicity of perfluorooctanoic acid in human hepatocytes using metabonomics].

  Se pu = Chinese journal of chromatography 20120201

• Synthesis of N-(2-chloro purin-6-yl) aza-18-crown-6 and its interaction with human serum albumin.

  Organic & biomolecular chemistry 20120128

• Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells.

  Toxicology 20120127

• Genotype-phenotype correlations in Lesch-Nyhan disease: moving beyond the gene.

  The Journal of biological chemistry 20120127

• Analysis of Camellia sinensis green and black teas via ultra high performance liquid chromatography assisted by liquid-liquid partition and two-dimensional liquid chromatography (size exclusion × reversed phase).

  Journal of chromatography. A 20120127

• Reactivity of the antitumor complex (H2trz)[trans-RuCl4(N2-Htrz)2] in the presence of DNA purines within a fluorinated silica matrix.

  The journal of physical chemistry. B 20120126

• Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase.

  Journal of molecular biology 20120120

• Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells.

  European journal of histochemistry : EJH 20120120

• Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer.

  British journal of cancer 20120117

• Core promoter STRs: novel mechanism for inter-individual variation in gene expression in humans.

  Gene 20120115

• Electrochemical oxidation of purine and pyrimidine bases based on the boron-doped nanotubes modified electrode.

  Biosensors & bioelectronics 20120115

• Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.

  Bioorganic & medicinal chemistry 20120115

• NMR analysis of the rat neurochemical changes induced by middle cerebral artery occlusion.

  Talanta 20120115

• Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins.

  Chemical communications (Cambridge, England) 20120114

• Low-energy electron scattering with the purine bases of DNA/RNA using the R-matrix method.

  The Journal of chemical physics 20120114

• Thymine dimer photoreversal in purine-containing trinucleotides.

  The journal of physical chemistry. B 20120112

• Formamide-based prebiotic synthesis of nucleobases: a kinetically accessible reaction route.

  The journal of physical chemistry. A 20120112

• Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase.

  Biochemistry 20120110

• Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation.

  Blood 20120105

• Divergence and convergence in enzyme evolution.

  The Journal of biological chemistry 20120102

• Site-specific control of N7-metal coordination in DNA by a fluorescent purine derivative.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120102

• Hepatosplenic gamma-delta T-cell lymphoma in a female patient after delivery.

  Hematology reports 20120102

• Magnetic resonance imaging of the brain in adenylosuccinate lyase deficiency: a report of seven cases and a review of the literature.

  European journal of pediatrics 20120101

• Cell tracking in cardiac repair: what to image and how to image.

  European radiology 20120101

• Benzene metabolite 1,2,4-benzenetriol induces halogenated DNA and tyrosines representing halogenative stress in the HL-60 human myeloid cell line.

  Environmental health perspectives 20120101

• Characterization of biofumigated Ralstonia solanacearum cells using micro-Raman spectroscopy and electron microscopy.

  Phytopathology 20120101

• Alterations in vasoconstrictor responses to the endothelium-derived contracting factor uridine adenosine tetraphosphate are region specific in DOCA-salt hypertensive rats.

  Pharmacological research 20120101

• Role of ARABIDOPSIS A-FIFTEEN in regulating leaf senescence involves response to reactive oxygen species and is dependent on ETHYLENE INSENSITIVE2.

  Journal of experimental botany 20120101

• Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates.

  Naunyn-Schmiedeberg's archives of pharmacology 20120101

• Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration.

  Cell stress & chaperones 20120101

• DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies.

  Bioinorganic chemistry and applications 20120101

• Adenosine and immune imbalance in visceral leishmaniasis: the possible role of ectonucleotidases.

  Journal of tropical medicine 20120101

• Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding.

  Journal of biomedicine & biotechnology 20120101

• Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir.

  Biochimie 20120101

• Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity.

  Pharmacological research 20120101

• Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis.

  Pharmacogenetics and genomics 20120101

• Reduction of the 'burst release' of copper ions from copper-based intrauterine devices by organic inhibitors.

  Contraception 20120101

• An update on the pathology and clinical management of gouty arthritis.

  Clinical rheumatology 20120101

• Fruit and vegetable and fried food consumption and 3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α] purin-10(3H)-one deoxyguanosine adduct formation.

  Free radical research 20120101

• Asymmetry of 13C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.

  Journal of biomolecular NMR 20120101

• Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia.

  Archives of biochemistry and biophysics 20120101

• Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides.

  European journal of medicinal chemistry 20120101

• Applicability of a sensitive duplex real-time PCR assay for identifying B/Yamagata and B/Victoria lineages of influenza virus from clinical specimens.

  Applied microbiology and biotechnology 20120101

• Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process.

  Journal of immunology (Baltimore, Md. : 1950) 20120101

• Structure-based design of PDK1 inhibitors.

  Bioorganic & medicinal chemistry letters 20120101

• Temozolomide: mechanisms of action, repair and resistance.

  Current molecular pharmacology 20120101

• Use of cyclosporine in uterine transplantation.

  Journal of transplantation 20120101

• Physiology, biochemistry and possible applications of microbial caffeine degradation.

  Applied microbiology and biotechnology 20120101

• Treatment of relapsed or refractory chronic lymphocytic leukemia.

  Cancer control : journal of the Moffitt Cancer Center 20120101

• Dissecting the role of glutathione biosynthesis in Plasmodium falciparum.

  Molecular microbiology 20120101

• Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS).

  Analytical and bioanalytical chemistry 20120101

• Recent advances in CSF biomarkers for Parkinson's disease.

  Parkinsonism & related disorders 20120101

• The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.

  Journal of oncology 20120101

• Uric acid, hyperuricemia and vascular diseases.

  Frontiers in bioscience (Landmark edition) 20120101

• Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia.

  Current gerontology and geriatrics research 20120101

• Metal-mediated base pairs in nucleic acids with purine- and pyrimidine-derived nucleosides.

  Metal ions in life sciences 20120101

• Proteomic analysis on acetate metabolism in Citrobacter sp. BL-4.

  International journal of biological sciences 20120101

• My treatment approach to hairy cell leukemia.

  Mayo Clinic proceedings 20120101

• On the molecular mechanism of GC content variation among eubacterial genomes.

  Biology direct 20120101

• Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome.

  Cardiovascular diabetology 20120101

• Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution.

  PLoS biology 20120101

• Down-regulation of myogenin can reverse terminal muscle cell differentiation.

  PloS one 20120101

• Genomic characterization of the Taylorella genus.

  PloS one 20120101

• Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows.

  BMC genomics 20120101

• Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system.

  Retrovirology 20120101

• Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.

  Cell death & disease 20120101

• TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome.

  PloS one 20120101

• Customisation of the exome data analysis pipeline using a combinatorial approach.

  PloS one 20120101

• Blue news update: BODIPY-GTP binds to the blue-light receptor YtvA while GTP does not.

  PloS one 20120101

• The architecture and ppGpp-dependent expression of the primary transcriptome of Salmonella Typhimurium during invasion gene expression.

  BMC genomics 20120101

• Integration of gene-based markers in a pearl millet genetic map for identification of candidate genes underlying drought tolerance quantitative trait loci.

  BMC plant biology 20120101

• Modulation of miRNA expression by dietary polyphenols in apoE deficient mice: a new mechanism of the action of polyphenols.

  PloS one 20120101

• Transcriptional ontogeny of the developing liver.

  BMC genomics 20120101

• Effects of adenosine A₂A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice.

  BMC infectious diseases 20120101

• Nucleotide and phylogenetic analyses of the Chlamydia trachomatis ompA gene indicates it is a hotspot for mutation.

  BMC research notes 20120101

• SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome.

  Cell & bioscience 20120101

• Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds.

  BMC developmental biology 20120101

• Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals.

  PloS one 20120101

• 5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer.

  International journal of nanomedicine 20120101

• Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor.

  PloS one 20120101

• Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis.

  PloS one 20120101

• Endothelial progenitor cells (EPCs) as gene carrier system for rat model of human glioma.

  PloS one 20120101

• Sequence coevolution between RNA and protein characterized by mutual information between residue triplets.

  PloS one 20120101

• HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

  PLoS pathogens 20120101

• Identification of novel candidate oncogenes in chromosome region 17p11.2-p12 in human osteosarcoma.

  PloS one 20120101

• Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses.

  PloS one 20120101

• High-resolution melting analysis as a powerful tool to discriminate and genotype Pseudomonas savastanoi pathovars and strains.

  PloS one 20120101

• The ζ toxin induces a set of protective responses and dormancy.

  PloS one 20120101

• A distinct metabolic signature predicts development of fasting plasma glucose.

  Journal of clinical bioinformatics 20120101

• Catalog of microRNA seed polymorphisms in vertebrates.

  PloS one 20120101

• Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease.

  PloS one 20120101

• microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers.

  Oncotarget 20120101

• Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter.

  BMC genomics 20120101

• Significance of dietary antioxidants for health.

  International journal of molecular sciences 20120101

• Astroglial excitability and gliotransmission: an appraisal of Ca2+ as a signalling route.

  ASN neuro 20120101

• African American patients with gout: efficacy and safety of febuxostat vs allopurinol.

  BMC musculoskeletal disorders 20120101

• Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction.

  BMC microbiology 20120101

• Deglutitive inhibition, latency between swallow and esophageal contractions and primary esophageal motor disorders.

  Journal of neurogastroenterology and motility 20120101

• Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia.

  Clinical Medicine Insights. Oncology 20120101

• Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection.

  Frontiers in microbiology 20120101

• Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region.

  PloS one 20120101

• Inhibitors of the cellular trafficking of ricin.

  Toxins 20120101

• Chemical approaches for structure and function of RNA in postgenomic era.

  Journal of nucleic acids 20120101

• Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2.

  PloS one 20120101

• Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm.

  PloS one 20120101

• Regulation of the let-7a-3 promoter by NF-κB.

  PloS one 20120101

• Blood-based gene expression profiles models for classification of subsyndromal symptomatic depression and major depressive disorder.

  PloS one 20120101

• A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy.

  PloS one 20120101

• Transcriptome analyses of a salt-tolerant cytokinin-deficient mutant reveal differential regulation of salt stress response by cytokinin deficiency.

  PloS one 20120101

• Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2.

  Viruses 20120101

• The interplay of mutations and electronic properties in disease-related genes.

  Scientific reports 20120101

• Protein-based identification of quantitative trait loci associated with malignant transformation in two HER2+ cellular models of breast cancer.

  Proteome science 20120101

• Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis.

  PloS one 20120101

• The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli.

  PloS one 20120101

• The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation.

  PloS one 20120101

• A measure of the promiscuity of proteins and characteristics of residues in the vicinity of the catalytic site that regulate promiscuity.

  PloS one 20120101

• A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.

  PloS one 20120101

• Targeted expression of Cre recombinase provokes placental-specific DNA recombination in transgenic mice.

  PloS one 20120101

• Identification of new splice sites used for generation of rev transcripts in human immunodeficiency virus type 1 subtype C primary isolates.

  PloS one 20120101

• LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor.

  PloS one 20120101

• New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.

  PloS one 20120101

• Neuromyelitis optica: an antibody-mediated disorder of the central nervous system.

  Neurology research international 20120101

• Protective effect of Emilia sonchifolia (L.) against high protein diet induced oxidative stress in pancreas of Wistar rats.

  Journal of pharmacy & bioallied sciences 20120101

• Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance.

  Cell division 20120101

• Analysis of intracellular expressed proteins of Mycobacterium tuberculosis clinical isolates.

  Proteome science 20120101

• Genetic polymorphisms of the TYMS gene are not associated with congenital cardiac septal defects in a Han Chinese population.

  PloS one 20120101

• Global transcriptome profiling of the pine shoot beetle, Tomicus yunnanensis (Coleoptera: Scolytinae).

  PloS one 20120101

• Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells.

  PloS one 20120101

• Genome-wide analysis of the emerging infection with Mycobacterium avium subspecies paratuberculosis in the Arabian camels (Camelus dromedarius).

  PloS one 20120101

• Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.

  PloS one 20120101

• Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain.

  Microbial cell factories 20120101

• New antiviral agents for hepatitis C.

  F1000 biology reports 20120101

• ArgR of Streptomyces coelicolor is a versatile regulator.

  PloS one 20120101

• Sirtuins as regulators of the yeast metabolic network.

  Frontiers in pharmacology 20120101

• Safety and efficacy of pemetrexed in maintenance therapy of non-small cell lung cancer.

  Clinical Medicine Insights. Oncology 20120101

• Identification of DreI as an antiviral factor regulated by RLR signaling pathway.

  PloS one 20120101

• Transcriptomics comparison between porcine adipose and bone marrow mesenchymal stem cells during in vitro osteogenic and adipogenic differentiation.

  PloS one 20120101

• Detailed mitochondrial phenotyping by high resolution metabolomics.

  PloS one 20120101

• Is Friedreich ataxia an epigenetic disorder?

  Clinical epigenetics 20120101

• Insight into trichomonas vaginalis genome evolution through metabolic pathways comparison.

  Bioinformation 20120101

• Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.

  Malaria journal 20120101

• Role of the gerA operon in L-alanine germination of Bacillus licheniformis spores.

  BMC microbiology 20120101

• A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model.

  BMC genomics 20120101

• Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells.

  Journal of neuroinflammation 20120101

• Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoa.

  PloS one 20120101

• Divergent roles of Salmonella pathogenicity island 2 and metabolic traits during interaction of S. enterica serovar typhimurium with host cells.

  PloS one 20120101

• Common changes in global gene expression induced by RNA polymerase inhibitors in Shigella flexneri.

  PloS one 20120101

• Pulmonary langerhans cell histiocytosis.

  Orphanet journal of rare diseases 20120101

• Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma.

  PloS one 20120101

• Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids.

  PloS one 20120101

• NF-κB as potential target in the treatment of melanoma.

  Journal of translational medicine 20120101

• Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance.

  BMC bioinformatics 20120101

• Quantitative proteome profiling of C. burnetii under tetracycline stress conditions.

  PloS one 20120101

• A deadenylase assay by size-exclusion chromatography.

  PloS one 20120101

• Transcriptome profiling of testis during sexual maturation stages in Eriocheir sinensis using Illumina sequencing.

  PloS one 20120101

• [Purine in common plant food in China].

  Wei sheng yan jiu = Journal of hygiene research 20120101

• Transcriptional profiling of ESTs from the biocontrol fungus Chaetomium cupreum.

  TheScientificWorldJournal 20120101

• Oxidative stress level in the testes of mice and rats during nickel intoxication.

  TheScientificWorldJournal 20120101

• Understanding communication signals during mycobacterial latency through predicted genome-wide protein interactions and boolean modeling.

  PloS one 20120101

• Different inhibitory potency of febuxostat towards mammalian and bacterial xanthine oxidoreductases: insight from molecular dynamics.

  Scientific reports 20120101

• Perturbation of cytokinin and ethylene-signalling pathways explain the strong rooting phenotype exhibited by Arabidopsis expressing the Schizosaccharomyces pombe mitotic inducer, cdc25.

  BMC plant biology 20120101

• Dietary habits in women with recurrent idiopathic calcium nephrolithiasis.

  Journal of translational medicine 20120101

• Management of cutaneous T cell lymphoma: new and emerging targets and treatment options.

  Cancer management and research 20120101

• Regular Multivitamin Supplement Use, Single Nucleotide Polymorphisms in ATIC, SHMT2, and SLC46A1, and Risk of Ovarian Carcinoma.

  Frontiers in genetics 20120101

• The use of mouse models for understanding the biology of down syndrome and aging.

  Current gerontology and geriatrics research 20120101

• The evolution of methotrexate as a treatment for ectopic pregnancy and gestational trophoblastic neoplasia: a review.

  ISRN obstetrics and gynecology 20120101

• Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction.

  ISRN cardiology 20120101

• Comparative proteomic analysis of early salt stress-responsive proteins in roots of SnRK2 transgenic rice.

  Proteome science 20120101

• Cellular Links between Neuronal Activity and Energy Homeostasis.

  Frontiers in pharmacology 20120101

• Characterization of an Nmr homolog that modulates GATA factor-mediated nitrogen metabolite repression in Cryptococcus neoformans.

  PloS one 20120101

• Genome sequence and transcriptome analysis of the radioresistant bacterium Deinococcus gobiensis: insights into the extreme environmental adaptations.

  PloS one 20120101

• State-of-the-Art Management of Patients Suffering from Chronic Lymphocytic Leukemia.

  Clinical Medicine Insights. Oncology 20120101

• From murine to human nude/SCID: the thymus, T-cell development and the missing link.

  Clinical & developmental immunology 20120101

• Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection.

  Journal of biological regulators and homeostatic agents 20120101

• High plasma uric acid concentration: causes and consequences.

  Diabetology & metabolic syndrome 20120101

• Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

  PloS one 20120101

• Identification of chromosomal genes in Yersinia pestis that influence type III secretion and delivery of Yops into target cells.

  PloS one 20120101

• Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA.

  PloS one 20120101

• Comparative analysis of gene content evolution in phytoplasmas and mycoplasmas.

  PloS one 20120101

• The complete mitochondrial genome of the small yellow croaker and partitioned Bayesian analysis of Sciaenidae fish phylogeny.

  Genetics and molecular biology 20120101

• Astragalin from Cassia alata induces DNA adducts in vitro and repairable DNA damage in the yeast Saccharomyces cerevisiae.

  International journal of molecular sciences 20120101

• Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats.

  PloS one 20120101

• Universal sequence replication, reversible polymerization and early functional biopolymers: a model for the initiation of prebiotic sequence evolution.

  PloS one 20120101

• Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes.

  BMC genomics 20120101

• A gestational high protein diet affects the abundance of muscle transcripts related to cell cycle regulation throughout development in porcine progeny.

  PloS one 20120101

• Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster.

  PloS one 20120101

• A family-wide RT-PCR assay for detection of paramyxoviruses and application to a large-scale surveillance study.

  PloS one 20120101

• Selection of suitable reference genes for RT-qPCR analyses in cyanobacteria.

  PloS one 20120101

• Channel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma brucei.

  PloS one 20120101

• The Chlamydia psittaci genome: a comparative analysis of intracellular pathogens.

  PloS one 20120101

• Complexity of the Mycoplasma fermentans M64 genome and metabolic essentiality and diversity among mycoplasmas.

  PloS one 20120101

• Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE).

  PloS one 20120101

• Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering.

  Nutrition & metabolism 20120101

• Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury.

  PloS one 20120101

• Altered calcium signaling following traumatic brain injury.

  Frontiers in pharmacology 20120101

• The HSP90 inhibitor NVP-AUY922 radiosensitizes by abrogation of homologous recombination resulting in mitotic entry with unresolved DNA damage.

  PloS one 20120101

• Multicenter uric acid biosensor based on tetrapod-shaped ZnO nanostructures.

  Journal of nanoscience and nanotechnology 20120101

• Endocannabinoid-dopamine interactions in striatal synaptic plasticity.

  Frontiers in pharmacology 20120101

• Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.

  PloS one 20120101

• The role of methylation in the intrinsic dynamics of B- and Z-DNA.

  PloS one 20120101

• The role of cytokines and inflammatory cells in perinatal brain injury.

  Neurology research international 20120101

• MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis.

  PloS one 20120101

• Update on treatment of follicular non-Hodgkin's lymphoma: focus on potential of bortezomib.

  Patient preference and adherence 20120101

• Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs.

  Comparative and functional genomics 20120101

• Novel therapies for aggressive B-cell lymphoma.

  Advances in hematology 20120101

• Network-based gene expression biomarkers for cold and heat patterns of rheumatoid arthritis in traditional chinese medicine.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Proteomics characterization of cytoplasmic and lipid-associated membrane proteins of human pathogen Mycoplasma fermentans M64.

  PloS one 20120101

• Does Branched-Chain Amino Acids Supplementation Modulate Skeletal Muscle Remodeling through Inflammation Modulation? Possible Mechanisms of Action.

  Journal of nutrition and metabolism 20120101

• Maximum expected accuracy structural neighbors of an RNA secondary structure.

  BMC bioinformatics 20120101

• Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity.

  ASN neuro 20120101

• [The characteristics of metabolism in patients with fractures of shin and thigh bones depending on immobilization period].

  Klinicheskaia laboratornaia diagnostika 20120101

• Bioguided Fractionation Shows Cassia alata Extract to Inhibit Staphylococcus epidermidis and Pseudomonas aeruginosa Growth and Biofilm Formation.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Current view on phytoplasma genomes and encoded metabolism.

  TheScientificWorldJournal 20120101

• An unanticipated difficult airway in Lesch-Nyhan syndrome.

  Journal of anaesthesiology, clinical pharmacology 20120101

• Metabolomic applications to decipher gut microbial metabolic influence in health and disease.

  Frontiers in physiology 20120101

• Reduced neurobehavioral impairment from sleep deprivation in older adults: contribution of adenosinergic mechanisms.

  Frontiers in neurology 20120101

• Protection of rat cardiac myocytes by fructose-1,6-bisphosphate and 2,3-butanedione.

  PloS one 20120101

• Deletion of Dicer in smooth muscle affects voiding pattern and reduces detrusor contractility and neuroeffector transmission.

  PloS one 20120101

• CRISPR interference directs strand specific spacer acquisition.

  PloS one 20120101

• Generation and analysis of a mouse intestinal metatranscriptome through Illumina based RNA-sequencing.

  PloS one 20120101

• Novel ATP-independent RNA annealing activity of the dengue virus NS3 helicase.

  PloS one 20120101

• Ammonia oxidizing bacteria community dynamics in a pilot-scale wastewater treatment plant.

  PloS one 20120101

• Astrocyte-specific disruption of SynCAM1 signaling results in ADHD-like behavioral manifestations.

  PloS one 20120101

• Plasma adenosine deaminase isoform 2 in cancer patients undergoing chemotherapy.

  British journal of biomedical science 20120101

• Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture.

  BMC medical genomics 20120101

• SIRT2 as a Therapeutic Target for Age-Related Disorders.

  Frontiers in pharmacology 20120101

• The dopamine D2 receptor gene in lamprey, its expression in the striatum and cellular effects of D2 receptor activation.

  PloS one 20120101

• IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening.

  PloS one 20120101

• Pokeweed antiviral protein increases HIV-1 particle infectivity by activating the cellular mitogen activated protein kinase pathway.

  PloS one 20120101

• The influence of autonomic dysfunction associated with aging and type 2 diabetes on daily life activities.

  Experimental diabetes research 20120101

• Riboflavin ameliorates cisplatin induced toxicities under photoillumination.

  PloS one 20120101

• Comparison of adenosine deaminase levels in serum and synovial fluid between patients with rheumatoid arthritis and osteoarthritis.

  International journal of clinical and experimental medicine 20120101

• Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation.

  Journal of neuroinflammation 20120101

• The fbpA/sapM double knock out strain of Mycobacterium tuberculosis is highly attenuated and immunogenic in macrophages.

  PloS one 20120101

• Efficacy and safety of low-dose everolimus as maintenance immunosuppression in cardiac transplant recipients.

  Journal of transplantation 20120101

• Dynamic metabolomics differentiates between carbon and energy starvation in recombinant Saccharomyces cerevisiae fermenting xylose.

  Biotechnology for biofuels 20120101

• Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction.

  Microbial informatics and experimentation 20120101

• Constitutive and treatment-induced CXCL8-signalling selectively modulates the efficacy of anti-metabolite therapeutics in metastatic prostate cancer.

  PloS one 20120101

• Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias.

  Current pharmaceutical design 20120101

• Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?

  Comparative and functional genomics 20120101

• New insights in staging and chemotherapy of African trypanosomiasis and possible contribution of medicinal plants.

  TheScientificWorldJournal 20120101

• Identification of novel potential β-N-acetyl-D-hexosaminidase inhibitors by virtual screening, molecular dynamics simulation and MM-PBSA calculations.

  International journal of molecular sciences 20120101

• Study of drug metabolism by xanthine oxidase.

  International journal of molecular sciences 20120101

• High nutrient transport and cycling potential revealed in the microbial metagenome of Australian sea lion (Neophoca cinerea) faeces.

  PloS one 20120101

• Differential actions of chlorhexidine on the cell wall of Bacillus subtilis and Escherichia coli.

  PloS one 20120101

• Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease.

  PloS one 20120101

• Percutaneous holmium laser fulguration of calyceal diverticula.

  Case reports in urology 20120101

• Comparative genome analysis of central nitrogen metabolism and its control by GlnR in the class Bacilli.

  BMC genomics 20120101

• Electrospray ionization mass spectrometry: a technique to access the information beyond the molecular weight of the analyte.

  International journal of analytical chemistry 20120101

• Transcriptome characterization by RNA-seq unravels the mechanisms of butyrate-induced epigenomic regulation in bovine cells.

  PloS one 20120101

• Uric acid is more strongly associated with impaired glucose regulation in women than in men from the general population: the KORA F4-Study.

  PloS one 20120101

• SUMOylation of paraflagellar rod protein, PFR1, and its stage-specific localization in Trypanosoma cruzi.

  PloS one 20120101

• Combined contribution of endothelial relaxing autacoides in the rat femoral artery response to CPCA: an adenosine A2 receptor agonist.

  TheScientificWorldJournal 20120101

• L-arginine intake effect on adenine nucleotide metabolism in rat parenchymal and reproductive tissues.

  TheScientificWorldJournal 20120101

• Effects of fatty acid treatments on the dexamethasone-induced intramuscular lipid accumulation in chickens.

  PloS one 20120101

• The chemoselective reduction of isoxazoline γ-lactams through iminium Aza-Diels-Alder reactions: a short-cut synthesis of aminols as valuable intermediates towards nucleoside derivatives.

  TheScientificWorldJournal 20120101

• The expression of small regulatory RNAs in clinical samples reflects the different life styles of Staphylococcus aureus in colonization vs. infection.

  PloS one 20120101

• Traffic-related air pollution and DNA damage: a longitudinal study in Taiwanese traffic conductors.

  PloS one 20120101

• Murine 3T3-L1 adipocyte cell differentiation model: validated reference genes for qPCR gene expression analysis.

  PloS one 20120101

• The plant mitochondrial carrier family: functional and evolutionary aspects.

  Frontiers in plant science 20120101

• Adenosine Methylation in Arabidopsis mRNA is Associated with the 3' End and Reduced Levels Cause Developmental Defects.

  Frontiers in plant science 20120101

• An expanding role for purine uptake permease-like transporters in plant secondary metabolism.

  Frontiers in plant science 20120101

• Acetaminophen induced cytotoxicity and altered gene expression in cultured cardiomyocytes of h(9)c(2) cells.

  Environmental health and toxicology 20120101

• Transport proteins regulate the flux of metabolites and cofactors across the membrane of plant peroxisomes.

  Frontiers in plant science 20120101

• Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line.

  Nucleosides, nucleotides & nucleic acids 20120101

• Oxidative stress and heart failure in altered thyroid States.

  TheScientificWorldJournal 20120101

• Is a genome a codeword of an error-correcting code?

  PloS one 20120101

• Targeting the Immune System to Fight Cancer Using Chemical Receptor Homing Vectors Carrying Polyinosine/Cytosine (PolyIC).

  Frontiers in oncology 20120101

• Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival.

  Frontiers in oncology 20120101

• Chemical constituents and biological activities of the genus Subergorgia.

  Pharmacognosy reviews 20120101

• Mast cell chemotaxis - chemoattractants and signaling pathways.

  Frontiers in immunology 20120101

• Thermodynamics of aryl-dihydroxyphenyl-thiadiazole binding to human Hsp90.

  PloS one 20120101

• Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd(2+) Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside.

  Journal of nucleic acids 20120101

• Effect and safety of mycophenolate mofetil or sodium in systemic sclerosis-associated interstitial lung disease: a meta-analysis.

  Pulmonary medicine 20120101

• Variable carbon catabolism among Salmonella enterica serovar Typhi isolates.

  PloS one 20120101

• Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

  PloS one 20120101

• Low dose vaccination with attenuated Francisella tularensis strain SchuS4 mutants protects against tularemia independent of the route of vaccination.

  PloS one 20120101

• A metabolomic approach to the study of wine micro-oxygenation.

  PloS one 20120101

• Metagenomic and metabolic profiling of nonlithifying and lithifying stromatolitic mats of Highborne Cay, The Bahamas.

  PloS one 20120101

• Phytocontact Dermatitis due to Mustard Seed Mimicking Burn Injury: Report of a Case.

  Case reports in medicine 20120101

• Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury.

  PloS one 20120101

• Biophysical characterization of the strong stabilization of the RNA triplex poly(U)•poly(A)*poly(U) by 9-O-(ω-amino) alkyl ether berberine analogs.

  PloS one 20120101

• Role of operon aaoSo-mutT in antioxidant defense in Streptococcus oligofermentans.

  PloS one 20120101

• Exploring the midgut transcriptome and brush border membrane vesicle proteome of the rice stem borer, Chilo suppressalis (Walker).

  PloS one 20120101

• Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis.

  International journal of Alzheimer's disease 20120101

• Mast cell adenosine receptors function: a focus on the a3 adenosine receptor and inflammation.

  Frontiers in immunology 20120101

• Tolerance-inducing strategies in islet transplantation.

  International journal of endocrinology 20120101

• Deep sequencing of the oral microbiome reveals signatures of periodontal disease.

  PloS one 20120101

• Cycling of Etk and Etp phosphorylation states is involved in formation of group 4 capsule by Escherichia coli.

  PloS one 20120101

• Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid.

  Nutrition journal 20120101

• Arsenic toxicity: the effects on plant metabolism.

  Frontiers in physiology 20120101

• An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review.

  Case reports in medicine 20120101

• The yin and yang of yeast transcription: elements of a global feedback system between metabolism and chromatin.

  PloS one 20120101

• A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family.

  PloS one 20120101

• The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin.

  PloS one 20120101

• Mechanism of oxidative stress in neurodegeneration.

  Oxidative medicine and cellular longevity 20120101

• Relationship between human aging muscle and oxidative system pathway.

  Oxidative medicine and cellular longevity 20120101

• The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection.

  Oxidative medicine and cellular longevity 20120101

• Quercetin Protects against Cadmium-Induced Renal Uric Acid Transport System Alteration and Lipid Metabolism Disorder in Rats.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Targeted therapy in Ewing sarcoma.

  ISRN oncology 20120101

• Effects of acute creatine supplementation on iron homeostasis and uric acid-based antioxidant capacity of plasma after wingate test.

  Journal of the International Society of Sports Nutrition 20120101

• R-roscovitine reduces lung inflammation induced by lipoteichoic acid and Streptococcus pneumoniae.

  Molecular medicine (Cambridge, Mass.) 20120101

• Overexpression of a maize sulfite oxidase gene in tobacco enhances tolerance to sulfite stress via sulfite oxidation and CAT-mediated H2O2 scavenging.

  PloS one 20120101

• Anti-prion activity of Brilliant Blue G.

  PloS one 20120101

• The antioxidant effects of a polyphenol-rich grape pomace extract in vitro do not correspond in vivo using exercise as an oxidant stimulus.

  Oxidative medicine and cellular longevity 20120101

• Preclinical and clinical evidence of antioxidant effects of antidepressant agents: implications for the pathophysiology of major depressive disorder.

  Oxidative medicine and cellular longevity 20120101

• Optical method for cardiovascular risk marker uric acid removal assessment during dialysis.

  TheScientificWorldJournal 20120101

• Genetics Techniques for Thermococcus kodakarensis.

  Frontiers in microbiology 20120101

• Microbial group specific uptake kinetics of inorganic phosphate and adenosine-5'-triphosphate (ATP) in the north pacific subtropical gyre.

  Frontiers in microbiology 20120101

• Amniotic fluid and amniotic membrane stem cells: marker discovery.

  Stem cells international 20120101

• The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study.

  PloS one 20120101

• ATPase cycle and DNA unwinding kinetics of RecG helicase.

  PloS one 20120101

• Proteomic analysis of Neisseria gonorrhoeae biofilms shows shift to anaerobic respiration and changes in nutrient transport and outermembrane proteins.

  PloS one 20120101

• Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.

  PloS one 20120101

• Structural analysis of Staphylococcus aureus serine/threonine kinase PknB.

  PloS one 20120101

• Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome.

  Journal of transplantation 20120101

• Evaluation of DNA damage induced by 2 polybrominated diphenyl ether flame retardants (BDE-47 and BDE-209) in SK-N-MC cells.

  International journal of toxicology 20120101

• Two Cases of Cerebral Involvement in Malignant Lymphoma (CD20+) That Responded to Combination Therapy with Rituximab and Cladribine.

  Case reports in oncology 20120101

• Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice.

  PloS one 20120101

• Novel cytokinin derivatives do not show negative effects on root growth and proliferation in submicromolar range.

  PloS one 20120101

• Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?

  PloS one 20120101

• Transcriptional profiling of serogroup B Neisseria meningitidis growing in human blood: an approach to vaccine antigen discovery.

  PloS one 20120101

• Oxidative damage in various tissues of rats exposed to radon.

  Journal of toxicology and environmental health. Part A 20120101

• Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes.

  Journal of nutrition and metabolism 20120101

• Serum uric acid level is an indicator of total cholesterol and low density lipoprotein cholesterol in men below 45 years in age but not older males.

  Clinical laboratory 20120101

• Mizoribine as sole immunosuppressive agent in islet xenotransplantation models: a candidate immunosuppressant causing no adverse effects on islets.

  Cell transplantation 20120101

• RY-Coding and Non-Homogeneous Models Can Ameliorate the Maximum-Likelihood Inferences From Nucleotide Sequence Data with Parallel Compositional Heterogeneity.

  Evolutionary bioinformatics online 20120101

• Analysis of 5'-mononucleotides in infant formula and adult/pediatric nutritional formula by liquid chromatography: First Action 2011.20.

  Journal of AOAC International 20120101

• HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21.

  Journal of AOAC International 20120101

• A case of hereditary xanthinuria type 1 accompanied by bilateral renal calculi.

  Internal medicine (Tokyo, Japan) 20120101

• Metabonomics biomarkers for subacute toxicity screening for benzene exposure in mice.

  Journal of toxicology and environmental health. Part A 20120101

• Associations between purine metabolites and clinical symptoms in schizophrenia.

  PloS one 20120101

• Effect of asynchronous transfer on bovine embryonic development and relationship with early cycle uterine proteome profiles.

  Reproduction, fertility, and development 20120101

• Mizoribine treatment for antihistamine-resistant chronic autoimmune urticaria.

  Dermatologic therapy 20120101

• Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.

  Frontiers in immunology 20120101

• Tools to kill: genome of one of the most destructive plant pathogenic fungi Macrophomina phaseolina.

  BMC genomics 20120101

• Cerebrospinal fluid metabolome in mood disorders-remission state has a unique metabolic profile.

  Scientific reports 20120101

• Listeria monocytogenes differential transcriptome analysis reveals temperature-dependent Agr regulation and suggests overlaps with other regulons.

  PloS one 20120101

• [Treatment for recurrent hairy cell leukemia].

  Terapevticheskii arkhiv 20120101

• Potential therapeutic drug target identification in Community Acquired-Methicillin Resistant Staphylococcus aureus (CA-MRSA) using computational analysis.

  Bioinformation 20120101

• Synthesis and antiviral evaluation of alpha-amino acid esters bearing N6-benzyladenine side chain.

  Acta poloniae pharmaceutica 20120101

• Role of supplementary L-carnitine in exercise and exercise recovery.

  Medicine and sport science 20120101

• [Scrining workers employed at the weapons and military technology recycling and disposal facilitie].

  Meditsina truda i promyshlennaia ekologiia 20120101

• Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs.

  Journal of pain research 20120101

• Mycophenolate mofetil (MMF) treatment efficacy in children with primary and secondary glomerulonephritis.

  Archives of medical science : AMS 20111231

• Electron donor-acceptor interactions with flanking purines influence the efficiency of thymine photodimerization.

  Journal of the American Chemical Society 20111228

• A modified alkaline Comet assay for in vivo detection of oxidative DNA damage in Drosophila melanogaster.

  Mutation research 20111224

• Monocyte-specific accessibility of a matrix attachment region in the tumor necrosis factor locus.

  The Journal of biological chemistry 20111223

• Formation of N-N cross-links in DNA by reaction of radiation-produced DNA base pair diradicals: a DFT study.

  The journal of physical chemistry. B 20111222

• Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing.

  Journal of medicinal chemistry 20111222

• Structure of (5'S)-8,5'-cyclo-2'-deoxyguanosine in DNA.

  Journal of the American Chemical Society 20111221

• High-temperature cultivation and 5' mRNA optimization are key factors for the efficient overexpression of thermostable Deinococcus geothermalis purine nucleoside phosphorylase in Escherichia coli.

  Journal of biotechnology 20111220

• Influence of sugar ring conformation on the transportability of nucleosides by human nucleoside transporters.

  Chembiochem : a European journal of chemical biology 20111216

• Cladribine inhibits cytokine secretion by T cells independently of deoxycytidine kinase activity.

  Journal of neuroimmunology 20111215

• Determination of pyrimidine and purine bases by reversed-phase capillary liquid chromatography with at-line surface-enhanced Raman spectroscopic detection employing a novel SERS substrate based on ZnS/CdSe silver-quantum dots.

  Analytical chemistry 20111215

• Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 2.

  Bioorganic & medicinal chemistry letters 20111215

• Mammalian DNA δ15N exhibits 40‰ intramolecular variation and is unresponsive to dietary protein level.

  Rapid communications in mass spectrometry : RCM 20111215

• Apnea stimulates the adaptive response to oxidative stress in elephant seal pups.

  The Journal of experimental biology 20111215

• MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans.

  The Journal of biological chemistry 20111209

• Differential activation of cAMP- and cGMP-dependent protein kinases by cyclic purine and pyrimidine nucleotides.

  Biochemical and biophysical research communications 20111202

• Interferon-alpha is a very effective salvage therapy for patients with hairy cell leukemia relapsing after cladribine: a report of three cases.

  Medical oncology (Northwood, London, England) 20111201

• Successful reduced-intensity SCT from unrelated cord blood in three patients with X-linked SCID.

  Bone marrow transplantation 20111201

• [Immunosuppressive treatments: mechanisms of action and clinical use].

  Nephrologie & therapeutique 20111201

• Methotrexate in the treatment of inflammatory bowel disease: an 8-year retrospective study in a Canadian pediatric IBD center.

  Inflammatory bowel diseases 20111201

• Consequence of one-electron oxidation and one-electron reduction for aniline.

  Journal of molecular modeling 20111201

• Non-gastric marginal zone B cell lymphoma: clinicopathologic features and treatment results.

  Annals of hematology 20111201

• Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice.

  Journal of physiology and biochemistry 20111201

• Study of the effect of presence or absence of protozoa on rumen fermentation and microbial protein contribution to the chyme.

  Journal of animal science 20111201

• Distinct fluctuations in nucleotide metabolism accompany the enhanced in vitro embryogenic capacity of Brassica cells over-expressing SHOOTMERISTEMLESS.

  Planta 20111201

• Can deliberately incomplete gene sample augmentation improve a phylogeny estimate for the advanced moths and butterflies (Hexapoda: Lepidoptera)?

  Systematic biology 20111201

• Underexpression of miR-224 in methotrexate resistant human colon cancer cells.

  Biochemical pharmacology 20111201

• A close relationship between primary nucleotides sequence structure and the composition of functional genes in the genome of prokaryotes.

  Molecular phylogenetics and evolution 20111201

• An integrative method for identifying the over-annotated protein-coding genes in microbial genomes.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20111201

• Shiga toxin 1 is more dependent on the P proteins of the ribosomal stalk for depurination activity than Shiga toxin 2.

  The international journal of biochemistry & cell biology 20111201

• Autoimmune neuromuscular disorders in childhood.

  Current treatment options in neurology 20111201

• Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma.

  The Journal of investigative dermatology 20111201

• Purification and characterization of Plasmodium yoelii adenosine deaminase.

  Experimental parasitology 20111201

• Response of Lactobacillus casei BL23 to phenolic compounds.

  Journal of applied microbiology 20111201

• PrcR, a PucR-type transcriptional activator, is essential for proline utilization and mediates proline-responsive expression of the proline utilization operon putBCP in Bacillus subtilis.

  Microbiology (Reading, England) 20111201

• N9-Substituted N⁶-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays.

  Bioorganic & medicinal chemistry 20111201

• Heroin affects purine nucleotides metabolism in rat brain.

  Neurochemistry international 20111201

• GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis.

  Nature chemical biology 20111201

• Synthesis of 6-(het) ary Xylocydine analogues and evaluating their inhibitory activities of CDK1 and CDK2 in vitro.

  Bioorganic & medicinal chemistry 20111201

• Evaluation of biological effects of nanomaterials. Part I. Cyto- and genotoxicity of nanosilver composites applied in textile technologies.

  International journal of occupational medicine and environmental health 20111201

• Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.

  Journal of biomolecular NMR 20111201

• Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells.

  Journal of immunology (Baltimore, Md. : 1950) 20111201

• Altering the electrostatic potential in the major groove: thermodynamic and structural characterization of 7-deaza-2'-deoxyadenosine:dT base pairing in DNA.

  The journal of physical chemistry. B 20111201

• How flexible are DNA constituents? The quantum-mechanical study.

  Journal of biomolecular structure & dynamics 20111201

• Mycophenolate mofetil for the induction and maintenance treatment of lupus nephritis.

  Immunotherapy 20111201

• Gout and hyperuricemia in Japan: perspectives for international research on purines and pyrimidines in man.

  Nucleosides, nucleotides & nucleic acids 20111201

• The PRPP synthetase spectrum: what does it demonstrate about nucleotide syndromes?

  Nucleosides, nucleotides & nucleic acids 20111201

• Initial studies to define the physiologic role of cN-II.

  Nucleosides, nucleotides & nucleic acids 20111201

• Inborn errors of purine and pyrimidine metabolism: how much we owe to H. Anne Simmonds.

  Nucleosides, nucleotides & nucleic acids 20111201

• Purine nucleoside phosphorylase deficiency: a mutation update.

  Nucleosides, nucleotides & nucleic acids 20111201

• Simultaneous determination of purine and pyrimidine metabolites in HPRT-deficient cell lines.

  Nucleosides, nucleotides & nucleic acids 20111201

• HPRT deficiency: identification of twenty-four novel variants including an unusual deep intronic mutation.

  Nucleosides, nucleotides & nucleic acids 20111201

• Molecular analysis of X-linked inborn errors of purine metabolism: HPRT1 and PRPS1 mutations.

  Nucleosides, nucleotides & nucleic acids 20111201

• Inborn errors in purine metabolism: role of 5'-nucleotidases and their involvement in the etiology of neurological impairments.

  Nucleosides, nucleotides & nucleic acids 20111201

• Increased expression of SLC2A9 decreases urate excretion from the kidney.

  Nucleosides, nucleotides & nucleic acids 20111201

• Apical voltage-driven urate efflux transporter NPT4 in renal proximal tubule.

  Nucleosides, nucleotides & nucleic acids 20111201

• May cyclic nucleotides be a source for abiotic RNA synthesis?

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20111201

• Origin, utilization, and recycling of nucleosides in the central nervous system.

  Advances in physiology education 20111201

• 15N and 13C{14N} NMR investigation of the major nitrogen-containing segment in an aquatic fulvic acid: evidence for a hydantoin derivative.

  Magnetic resonance in chemistry : MRC 20111201

• Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues.

  PLoS computational biology 20111201

• Comparison and evaluation of different methodologies and tests for detection of anti-dsDNA antibodies on 889 Slovenian patients' and blood donors' sera.

  Croatian medical journal 20111201

• In vivo expression of Salmonella enterica serotype Typhi genes in the blood of patients with typhoid fever in Bangladesh.

  PLoS neglected tropical diseases 20111201

• Moderate exercise training promotes adaptations in coronary blood flow and adenosine production in normotensive rats.

  Clinics (Sao Paulo, Brazil) 20111201

• Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development.

  PLoS genetics 20111201

• High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.

  PLoS neglected tropical diseases 20111201

• Genome comparison of human and non-human malaria parasites reveals species subset-specific genes potentially linked to human disease.

  PLoS computational biology 20111201

• Recent progress in targeting cancer.

  Aging 20111201

• Treatment of myasthenia gravis based on its immunopathogenesis.

  Journal of clinical neurology (Seoul, Korea) 20111201

• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats.

  Journal of toxicologic pathology 20111201

• Inhibition of Inducible Nitric Oxide Synthase Attenuates Monosodium Urate-induced Inflammation in Mice.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20111201

• Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

  G3 (Bethesda, Md.) 20111201

• [The detection of minimal residual disease in patients with chronic B-cell lymphatic leukemia using patient-specified polymerase chain reaction].

  Klinicheskaia laboratornaia diagnostika 20111201

• cGMP Signaling, Phosphodiesterases and Major Depressive Disorder.

  Current neuropharmacology 20111201

• Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.

  Biochemistry 20111129

• Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide.

  The Journal of biological chemistry 20111125

• Direct arylation of 6-phenylpurine and 6-arylpurine nucleosides by ruthenium-catalyzed C-H bond activation.

  Angewandte Chemie (International ed. in English) 20111125

• [Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities].

  Postepy higieny i medycyny doswiadczalnej (Online) 20111123

• A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique.

  Clinica chimica acta; international journal of clinical chemistry 20111120

• Fluorescence detection of GDP in real time with the reagentless biosensor rhodamine-ParM.

  The Biochemical journal 20111115

• Synthesis of purine modified 2'-C-methyl nucleosides as potential anti-HCV agents.

  Bioorganic & medicinal chemistry letters 20111115

• Signaling pathways: Purinosomes under GPCR control.

  Nature chemical biology 20111115

• Theoretical molecular double-core-hole spectroscopy of nucleobases.

  The journal of physical chemistry. A 20111110

• Genome sequencing reveals insights into physiology and longevity of the naked mole rat.

  Nature 20111110

• Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes.

  The Journal of biological chemistry 20111104

• Bisphenol A-glycidyl methacrylate induces a broad spectrum of DNA damage in human lymphocytes.

  Archives of toxicology 20111101

• Clofarabine and high-dose cytosine arabinoside in the treatment of refractory or relapsed acute myeloid leukaemia.

  Annals of hematology 20111101

• Ultra-diffuse hydrothermal venting supports Fe-oxidizing bacteria and massive umber deposition at 5000 m off Hawaii.

  The ISME journal 20111101

• The protective effects of inosine against chemical hypoxia on cultured rat oligodendrocytes.

  Cellular and molecular neurobiology 20111101

• Effects of levosimendan on cardiac gene expression profile and post-infarct cardiac remodelling in diabetic Goto-Kakizaki rats.

  Basic & clinical pharmacology & toxicology 20111101

• Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma.

  International journal of oncology 20111101

• On the evolution of arterial vascular patterns of tetrapods.

  Journal of morphology 20111101

• Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells.

  European journal of cancer (Oxford, England : 1990) 20111101

• Highly regioselective synthesis of undecylenic acid esters of purine nucleosides catalyzed by Candida antarctica lipase B.

  Biotechnology letters 20111101

• Variety of genomic DNA patterns for nucleosome positioning.

  Genome research 20111101

• Purine P2Y receptors in ATP-mediated regulation of non-quantal acetylcholine release from motor nerve endings of rat diaphragm.

  Neuroscience research 20111101

• Purine scaffold effect on fluorescence properties of purine-hydroxyquinolinone bisheterocycles.

  Journal of fluorescence 20111101

• The polypyrimidine/polypurine motif in the mouse mu opioid receptor gene promoter is a supercoiling-regulatory element.

  Gene 20111101

• Uridine adenosine tetraphosphate induces contraction of airway smooth muscle.

  American journal of physiology. Lung cellular and molecular physiology 20111101

• Evidence for the localization of the Arabidopsis cytokinin receptors AHK3 and AHK4 in the endoplasmic reticulum.

  Journal of experimental botany 20111101

• Decreased oxidative phosphorylation and PGAM deficiency in horses suffering from atypical myopathy associated with acquired MADD.

  Molecular genetics and metabolism 20111101

• Pyrimidine degradation influences germination seedling growth and production of Arabidopsis seeds.

  Journal of experimental botany 20111101

• Gene set analysis of purine and pyrimidine antimetabolites cancer therapies.

  Pharmacogenetics and genomics 20111101

• Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion.

  British journal of anaesthesia 20111101

• Advances in acute lymphoblastic leukemia in adults.

  Current opinion in oncology 20111101

• KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.

  British journal of haematology 20111101

• Stability and mismatch discrimination of locked nucleic acid-DNA duplexes.

  Biochemistry 20111101

• Silver(I)-mediated Hoogsteen-type base pairs.

  Journal of inorganic biochemistry 20111101

• [Metabolic myopathies - part II: disorders of the fat, purine, and oxidative energy metabolism].

  Fortschritte der Neurologie-Psychiatrie 20111101

• [Antimetabolites].

  Bulletin du cancer 20111101

• Release of extracellular purines from plant roots and effect on ion fluxes.

  Plant signaling & behavior 20111101

• An HPLC-based assay of adenylosuccinate lyase in erythrocytes.

  Nucleosides, nucleotides & nucleic acids 20111101

• Synthesis of (glycopyranosyl-triazolyl)-purines and their inhibitory activities against protein tyrosine phosphatase 1B (PTP1B).

  Chemistry & biodiversity 20111101

• The ADA*2 allele of the adenosine deaminase gene (20q13.11) and recurrent spontaneous abortions: an age-dependent association.

  Clinics (Sao Paulo, Brazil) 20111101

• The role of the P2X₇ receptor in infectious diseases.

  PLoS pathogens 20111101

• Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.

  PLoS pathogens 20111101

• EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription.

  PLoS pathogens 20111101

• Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont.

  PLoS genetics 20111101

• Bis(7-amino-1,2,4-triazolo[1,5-a]pyrimidin-4-ium) bis-(oxalato-κO,O)cuprate(II) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Experimental determination and prediction of bilitranslocase transport activity.

  Analytica chimica acta 20111031

• Antifouling properties of simple indole and purine alkaloids from the Mediterranean gorgonian Paramuricea clavata.

  Journal of natural products 20111028

• Ongoing trials in low-grade lymphoma.

  Hematology reports 20111028

• A vestige of a prebiotic bonding machine is functioning within the contemporary ribosome.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20111027

• 8-(p-CF3-cinnamyl)-modified purine nucleosides as promising fluorescent probes.

  Organic & biomolecular chemistry 20111026

• Rat liver mitochondrial proteome: changes associated with aging and acetyl-L-carnitine treatment.

  Journal of proteomics 20111019

• Therapy related acute myeloid leukemia with t(10:16): a rare entity.

  Hematology reports 20111019

• Fluorescent properties and conformational preferences of C-linked phenolic-DNA adducts.

  Chemical research in toxicology 20111017

• Discovery of potent, metabolically stable purine CRF-1 antagonists with differentiated binding kinetic profiles.

  Bioorganic & medicinal chemistry letters 20111015

• Novel 4-azasteroidal N-glycoside analogues bearing sugar-like D ring: synthesis and anticancer activities.

  Bioorganic & medicinal chemistry letters 20111015

• Biochemical regulation of sleep and sleep biomarkers.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20111015

• Identification and modeling of a phosphatase-like domain in a tRNA 2'-O-ribosyl phosphate transferase Rit1p.

  Cell cycle (Georgetown, Tex.) 20111015

• Complete genome sequence of Staphylothermus hellenicus P8.

  Standards in genomic sciences 20111015

• Anharmonic vibrational modes of nucleic acid bases revealed by 2D IR spectroscopy.

  Journal of the American Chemical Society 20111005

• Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view.

  Antioxidants & redox signaling 20111001

• Therapeutic management of chronic lymphocytic leukaemia: state of the art and future perspectives.

  Critical reviews in oncology/hematology 20111001

• Extracorporeal photopheresis in addition to pentostatin in conditioning for canine hematopoietic cell transplantation: role in engraftment.

  Bone marrow transplantation 20111001

• Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome.

  Urological research 20111001

• Elevated airway purines in COPD.

  Chest 20111001

• Links between hydrothermal environments, pyrophosphate, na(+), and early evolution.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20111001

• Adsorption of ribose nucleotides on manganese oxides with varied mn/o ratio: implications for chemical evolution.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20111001

• Unraveling the structural and functional differences between purine nucleoside phosphorylase and 5'-deoxy-5'-methylthioadenosine phosphorylase from the archaeon Pyrococcus furiosus.

  Biochimica et biophysica acta 20111001

• Analysis of muscle and ovary transcriptome of Sus scrofa: assembly, annotation and marker discovery.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20111001

• Triplet-state dynamics of a metalloporphyrin photosensitiser (PtTMPyP4) in the presence of halides and purine mononucleotides.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001

• Structure-activity relationships on purine and 2,3-dihydropurine derivatives as antitubercular agents: a data mining approach.

  Chemical biology & drug design 20111001

• Phosphoribosylamidotransferase, the first enzyme for purine de novo synthesis, is required for conidiation in the sclerotial mycoparasite Coniothyrium minitans.

  Fungal genetics and biology : FG & B 20111001

• A universal real-time assay for the detection of Lyssaviruses.

  Journal of virological methods 20111001

• Profile-statistical periodicity of DNA coding regions.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20111001

• Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic method.

  Analytical and bioanalytical chemistry 20111001

• Effects of purine nucleoside phosphorylase deficiency on thymocyte development.

  The Journal of allergy and clinical immunology 20111001

• [Clinical strategies for prevention of drug-induced urinary calculi].

  Clinical calcium 20111001

• Synthesis of novel 6'-spirocyclopropyl-5'-norcarbocyclic adenosine phosphonic Acid analogues as potent anti-hiv agents.

  Nucleosides, nucleotides & nucleic acids 20111001

• Design and synthesis of carbocyclic versions of furanoid nucleoside phosphonic Acid analogues as potential anti-hiv agents.

  Nucleosides, nucleotides & nucleic acids 20111001

• Changes in renal function after different tandem hematopoietic stem-cell transplantation approaches in patients with multiple myeloma.

  Journal of Korean medical science 20111001

• Endophytic life strategies decoded by genome and transcriptome analyses of the mutualistic root symbiont Piriformospora indica.

  PLoS pathogens 20111001

• Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever.

  PLoS neglected tropical diseases 20111001

• Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression.

  PLoS neglected tropical diseases 20111001

• 1-(3-Chloro-phen-yl)-2-methyl-4-nitro-1H-imidazole-5-carboxamide.

  Acta crystallographica. Section E, Structure reports online 20111001

• 4-Sulfamoylanilinium nitrate.

  Acta crystallographica. Section E, Structure reports online 20111001

• The molecular biology of frog virus 3 and other iridoviruses infecting cold-blooded vertebrates.

  Viruses 20111001

• Subcellular localization of N-deoxyribosyltransferase in Lactobacillus fermentum: cell surface association of an intracellular nucleotide metabolic enzyme.

  FEMS microbiology letters 20111001

• Protective effect of methanol extract from citrus press cakes prepared by far-infrared radiation drying on H(2)O(2)-mediated oxidative damage in Vero cells.

  Nutrition research and practice 20111001

• [Effect of adenine on metabolic fluxes in Escherichia coli DH5alpha and its acetate-tolerant mutant DA19].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20111001

• NMR-based substrate analog docking to Escherichia coli peptidyl-tRNA hydrolase.

  Journal of molecular biology 20110930

• High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation.

  Blood 20110929

• Crystal structure of the β2 adrenergic receptor-Gs protein complex.

  Nature 20110929

• Colourimetric and spectroscopic discrimination between nucleotides and nucleosides using para-sulfonato-calix[4]arene capped silver nanoparticles.

  Chemical communications (Cambridge, England) 20110928

• Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines.

  Physical chemistry chemical physics : PCCP 20110921

• A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair.

  Journal of the American Chemical Society 20110921

• Biochemistry of uridine in plasma.

  Clinica chimica acta; international journal of clinical chemistry 20110918

• Mining endonuclease cleavage determinants in genomic sequence data.

  The Journal of biological chemistry 20110916

• Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

  The Journal of biological chemistry 20110916

• Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy.

  Bioorganic & medicinal chemistry letters 20110915

• Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness.

  Bioorganic & medicinal chemistry letters 20110915

• 2-Oxoglycosyl ('ulosyl') and 2-oximinoglycosyl bromides: versatile donors for the expedient assembly of oligosaccharides with β-D-mannose, β-L-rhamnose, N-acetyl-β-D-mannosamine, and N-acetyl-β-D-mannosaminuronic acid units.

  Chemical reviews 20110914

• Direct C-H arylation of purine on solid phase and its use for chemical libraries synthesis.

  ACS combinatorial science 20110912

• Experimental and theoretical study of the metastable decay of negatively charged nucleosides in the gas phase.

  Physical chemistry chemical physics : PCCP 20110907

• iTRAQ-based quantitative proteomic analysis of Thermobifida fusca reveals metabolic pathways of cellulose utilization.

  Journal of proteomics 20110906

• Fluorescence properties of 8-(2-pyridyl)guanine '2PyG' as compared to 2-aminopurine in DNA.

  Chembiochem : a European journal of chemical biology 20110905

• Physiological and toxic effects of purine intermediate 5-amino-4-imidazolecarboxamide ribonucleotide (AICAR) in yeast.

  The Journal of biological chemistry 20110902

• Global proteomics analysis of testis and ovary in adult zebrafish (Danio rerio).

  Fish physiology and biochemistry 20110901

• RNA and protein 3D structure modeling: similarities and differences.

  Journal of molecular modeling 20110901

• Effect of training load structure on purine metabolism in middle-distance runners.

  Medicine and science in sports and exercise 20110901

• Pharmacochemistry of the platelet purinergic receptors.

  Purinergic signalling 20110901

• Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases.

  Angiogenesis 20110901

• Technical note: The persistence of microbial-specific DNA sequences through gastric digestion in lambs and their potential use as microbial markers.

  Journal of animal science 20110901

• Suppression of inflammation response by a novel A₃ adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling.

  Immunobiology 20110901

• The improvement of riboflavin production in Ashbya gossypii via disparity mutagenesis and DNA microarray analysis.

  Applied microbiology and biotechnology 20110901

• Hypoglycemia and glycemic variability among children with acute lymphoblastic leukemia during maintenance therapy.

  Leukemia & lymphoma 20110901

• B-DNA to zip-DNA: simulating a DNA transition to a novel structure with enhanced charge-transport characteristics.

  The journal of physical chemistry. A 20110901

• Gene expression profiling of peripheral blood leukocytes identifies and validates ABCB1 as a novel biomarker for Alzheimer's disease.

  Neurobiology of disease 20110901

• Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.

  Biochimie 20110901

• purL gene expression affects biofilm formation and symbiotic persistence of Photorhabdus temperata in the nematode Heterorhabditis bacteriophora.

  Microbiology (Reading, England) 20110901

• Effect of growth under selection on appearance of chromosomal mutations in Salmonella enterica.

  Genetics 20110901

• Impact of histidine residue on chelating ability of 2'-deoxyriboadenosine.

  Journal of inorganic biochemistry 20110901

• Safety and efficacy of febuxostat treatment in subjects with gout and severe allopurinol adverse reactions.

  The Journal of rheumatology 20110901

• Enzymatic dissolution of calcium and struvite crystals: in vitro evaluation of biochemical requirements.

  Urology 20110901

• Identification of immunodeficient molecules in neonatal mononuclear cells by proteomic differential displays.

  Proteomics 20110901

• Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110901

• Xanthine oxidoreductase: a journey from purine metabolism to cardiovascular excitation-contraction coupling.

  Critical reviews in biotechnology 20110901

• Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia.

  Journal of neurochemistry 20110901

• NMR structure of a 4 x 4 nucleotide RNA internal loop from an R2 retrotransposon: identification of a three purine-purine sheared pair motif and comparison to MC-SYM predictions.

  RNA (New York, N.Y.) 20110901

• Potential teratogenic effects of allopurinol: a case report.

  American journal of medical genetics. Part A 20110901

• A decade of targets and patented drugs for chemotherapy of Chagas disease.

  Recent patents on anti-infective drug discovery 20110901

• Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110901

• Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole.

  PLoS pathogens 20110901

• A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients.

  PLoS pathogens 20110901

• Chronic arsenic toxicity: studies in West Bengal, India.

  The Kaohsiung journal of medical sciences 20110901

• A case of exercise-induced acute renal failure with G774A mutation in SCL22A12 causing renal hypouricemia.

  Journal of Korean medical science 20110901

• Urate transporters: an evolving field.

  Seminars in nephrology 20110901

• 8-(2-Hy-droxy-phen-yl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione.

  Acta crystallographica. Section E, Structure reports online 20110901

• Low-grade lymphoma: Beyond fludarabine-single therapy.

  The Korean journal of hematology 20110901

• Fludarabine-containing chemotherapy for patients with previously untreated low-grade non-Hodgkin's lymphoma.

  The Korean journal of hematology 20110901

• Expressed sequence tag analysis of the erythrocytic stage of Plasmodium berghei.

  The Korean journal of parasitology 20110901

• New insights into neuromyelitis optica.

  Journal of clinical neurology (Seoul, Korea) 20110901

• Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes.

  Clinics (Sao Paulo, Brazil) 20110901

• First Steps Towards an Understanding of a Mode ofCarcinogenic Action for Vanadium Pentoxide.

  Journal of toxicologic pathology 20110901

• Effects of ramadan fasting on biochemical and anthropometric parameters in physically active men.

  Asian journal of sports medicine 20110901

• Autoimmune neuromuscular disorders.

  Current neuropharmacology 20110901

• Multiple sclerosis: pathogenesis and treatment.

  Current neuropharmacology 20110901

• Idiopathic transverse myelitis and neuromyelitis optica: clinical profiles, pathophysiology and therapeutic choices.

  Current neuropharmacology 20110901

• Neuropsychiatric systemic lupus erythematosus.

  Current neuropharmacology 20110901

• Toxicities of immunosuppressive treatment of autoimmune neurologic diseases.

  Current neuropharmacology 20110901

• Pt(II) coordination to N1 of 9-methylguanine: why it facilitates binding of additional metal ions to the purine ring.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110829

• 2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA.

  Chemistry & biology 20110826

• In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia.

  Blood 20110825

• Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates.

  Journal of medicinal chemistry 20110825

• Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction.

  Science translational medicine 20110824

• B family DNA polymerases asymmetrically recognize pyrimidines and purines.

  Biochemistry 20110823

• CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease.

  Brain research 20110823

• Two parallel pathways in the kinetic sequence of the dihydrofolate reductase from Mycobacterium tuberculosis.

  Biochemistry 20110816

• Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases.

  Biochemical pharmacology 20110815

• Increasing the speed limit for hole transport in DNA.

  Journal of the American Chemical Society 20110803

• Interactions of cations with RNA loop-loop complexes.

  Biophysical journal 20110803

• Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium.

  American journal of respiratory cell and molecular biology 20110801

• Arbuscular mycorrhizal symbiosis elicits proteome responses opposite of P-starvation in SO4 grapevine rootstock upon root colonisation with two Glomus species.

  Mycorrhiza 20110801

• High throughput screening of small molecule libraries for modifiers of radiation responses.

  International journal of radiation biology 20110801

• Effects of ischemia and reperfusion on P2X2 receptor expressing neurons of the rat ileum enteric nervous system.

  Digestive diseases and sciences 20110801

• Completing the purine utilisation pathway of Aspergillus nidulans.

  Fungal genetics and biology : FG & B 20110801

• De novo engineering and metabolic flux analysis of inosine biosynthesis in Bacillus subtilis.

  Biotechnology letters 20110801

• Alterations in DNA metabolism in Elliptio complanata mussels after exposure to municipal effluents.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110801

• Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.

  Annals of the rheumatic diseases 20110801

• Electrochemical behaviour of carbon paste electrodes enriched with tin oxide nanoparticles using voltammetry and electrochemical impedance spectroscopy.

  Colloids and surfaces. B, Biointerfaces 20110801

• Uridine adenosine tetraphosphate-induced contraction is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats.

  American journal of physiology. Heart and circulatory physiology 20110801

• Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells.

  European journal of pharmacology 20110801

• Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells.

  American journal of physiology. Cell physiology 20110801

• Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.

  Environmental research 20110801

• Increased glutamine in leaves of poplar transgenic with pine GS1a caused greater anthranilate synthetase α-subunit (ASA1) transcript and protein abundances: an auxin-related mechanism for enhanced growth in GS transgenics?

  Journal of experimental botany 20110801

• Equilibrative nucleoside transporter 1 (ENT1) is critical for pollen germination and vegetative growth in Arabidopsis.

  Journal of experimental botany 20110801

• Which one among the Pt-containing anticancer drugs more easily forms monoadducts with G and A DNA bases? A comparative study among oxaliplatin, nedaplatin, and carboplatin.

  Inorganic chemistry 20110801

• Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication.

  Bioorganic & medicinal chemistry 20110801

• A model of proto-anti-codon RNA enzymes requiring L-amino acid homochirality.

  Journal of molecular evolution 20110801

• The lifestyle of the segmented filamentous bacterium: a non-culturable gut-associated immunostimulating microbe inferred by whole-genome sequencing.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20110801

• Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.

  Acta crystallographica. Section D, Biological crystallography 20110801

• Inflammatory bowel disease: perioperative pharmacological considerations.

  Mayo Clinic proceedings 20110801

• Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication.

  PLoS computational biology 20110801

• Variance of gene expression identifies altered network constraints in neurological disease.

  PLoS genetics 20110801

• [Novel conventional therapies in onco-hemathology].

  Bulletin du cancer 20110801

• Salmonella bongori provides insights into the evolution of the Salmonellae.

  PLoS pathogens 20110801

• Improving the outcomes of elderly patients with acute myeloid leukemia in a Brazilian University Hospital.

  Clinics (Sao Paulo, Brazil) 20110801

• Effects of mycophenolate sodium on mucociliary clearance using a bronchial section and anastomosis rodent model.

  Clinics (Sao Paulo, Brazil) 20110801

• Modes of action of microbially-produced phytotoxins.

  Toxins 20110801

• Complications of nephrotic syndrome.

  Korean journal of pediatrics 20110801

• Genetics and mitochondrial abnormalities in autism spectrum disorders: a review.

  Current genomics 20110801

• Genomic organization of leishmania species.

  Iranian journal of parasitology 20110801

• Pecularities of prolonged use of moxonidine in patients with hypertension associated with metabolic syndrome.

  Bulletin of experimental biology and medicine 20110801

• Difficult-to-treat gouty arthritis: a disease warranting better management.

  Drugs 20110730

• Peculiarities of homooligonucleotides wrapping around carbon nanotubes: molecular dynamics modeling.

  The journal of physical chemistry. B 20110728

• High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode.

  Journal of chromatography. A 20110722

• Allosteric nucleotide-binding site in the mitochondrial NADH:ubiquinone oxidoreductase (respiratory complex I).

  FEBS letters 20110721

• CuBr catalyzed C-N cross coupling reaction of purines and diaryliodonium salts to 9-arylpurines.

  Organic & biomolecular chemistry 20110721

• Strengthening the stability of a tunnel-shaped homotetramer protein with nanogels.

  The journal of physical chemistry. B 20110721

• Repair of the major lesion resulting from C5'-oxidation of DNA.

  Biochemistry 20110719

• γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.

  Chemical research in toxicology 20110718

• SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors.

  Bioorganic & medicinal chemistry letters 20110715

• Progress in structure based drug design for G protein-coupled receptors.

  Journal of medicinal chemistry 20110714

• Escherichia coli Fpg glycosylase is nonrendundant and required for the rapid global repair of oxidized purine and pyrimidine damage in vivo.

  Journal of molecular biology 20110708

• Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase.

  Chembiochem : a European journal of chemical biology 20110704

• Novel 1,2,4-triazole and purine acyclic cyclopropane nucleoside analogues: synthesis, antiviral and cytostatic activity evaluations.

  Antiviral chemistry & chemotherapy 20110704

• Manipulations of AMP metabolic genes increase growth rate and cold tolerance in Escherichia coli: implications for psychrophilic evolution.

  Molecular biology and evolution 20110701

• An animal model for measuring the effect of common NICU procedures on ATP metabolism.

  Biological research for nursing 20110701

• Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-κB pathways in intestinal epithelial cells.

  Mucosal immunology 20110701

• The biochemistry of nitrogen mobilization: purine ring catabolism.

  Trends in plant science 20110701

• Regulation of pentose utilisation by AraR, but not XlnR, differs in Aspergillus nidulans and Aspergillus niger.

  Applied microbiology and biotechnology 20110701

• Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate.

  Molecular pharmacology 20110701

• Xanthine oxidase inhibitors: a patent survey.

  Expert opinion on therapeutic patents 20110701

• In vitro and in vivo biological activity screening of Ru(III) complexes involving 6-benzylaminopurine derivatives with higher pro-apoptotic activity than NAMI-A.

  Journal of inorganic biochemistry 20110701

• The effect of red pigment on the amyloidization of yeast proteins.

  Yeast (Chichester, England) 20110701

• Receptor-like activity evoked by extracellular ADP in Arabidopsis root epidermal plasma membrane.

  Plant physiology 20110701

• Clofarabine for myelodysplastic syndromes.

  Expert opinion on investigational drugs 20110701

• Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation.

  The New phytologist 20110701

• Synthesis of purine nucleosides built on a 3-oxabicyclo[3.2.0]heptane scaffold.

  The Journal of organic chemistry 20110701

• Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.

  Nature structural & molecular biology 20110701

• Molecular basis of P2-receptor-mediated calcium signaling in activated pancreatic stellate cells.

  Pancreas 20110701

• Identification of prognostic factors for plerixafor-based hematopoietic stem cell mobilization.

  American journal of hematology 20110701

• The human caveolin 1 gene upstream purine complex and neurodegeneration--a common signature.

  Journal of neuroimmunology 20110701

• Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: a retrospective analysis of data from 2 phase III clinical trials.

  Clinical therapeutics 20110701

• Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma.

  Nature communications 20110701

• Treatment of elderly patients with mantle cell lymphoma.

  Seminars in hematology 20110701

• In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis.

  PLoS pathogens 20110701

• Improved PCR-RFLP for the detection of diminazene resistance in Trypanosoma congolense under field conditions using filter papers for sample storage.

  PLoS neglected tropical diseases 20110701

• Alcohol consumption and oxidative DNA damage.

  International journal of environmental research and public health 20110701

• [Mutation analysis of the purine operon leader region in Bacillus subtilis].

  Genetika 20110701

• Preventive and therapeutic strategies for bovine leukemia virus: lessons for HTLV.

  Viruses 20110701

• [Different expression of protein in the supernatant of heat injured keratinocytes].

  Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20110701

• Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept.

  Translational psychiatry 20110701

• Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs.

  Bulletin of experimental biology and medicine 20110701

• Characterization of an ecto-5'-nucleotidase activity present on the cell surface of Tritrichomonas foetus.

  Veterinary parasitology 20110630

• Combined effect of CYP1B1, COMT, GSTP1, and MnSOD genotypes and risk of postmenopausal breast cancer.

  Journal of gynecologic oncology 20110630

• Analysis of regulation of pentose utilisation in Aspergillus niger reveals evolutionary adaptations in Eurotiales.

  Studies in mycology 20110630

• Transition-state analysis of Trypanosoma cruzi uridine phosphorylase-catalyzed arsenolysis of uridine.

  Journal of the American Chemical Society 20110629

• Reduced intensity transplantation for primary immunodeficiency disorders.

  Pediatric reports 20110622

• Aplastic anemia: immunosuppressive therapy in 2010.

  Pediatric reports 20110622

• Novel chemically defined approach to produce multipotent cells from terminally differentiated tissue syncytia.

  ACS chemical biology 20110617

• Molecular chemotherapy and chemotherapy: a new front against late-stage hormone-refractory prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110615

• Inhibition of xanthine oxidase by thiosemicarbazones, hydrazones and dithiocarbazates derived from hydroxy-substituted benzaldehydes.

  ChemMedChem 20110606

• Evidence for the existence of a specific g protein-coupled receptor activated by guanosine.

  ChemMedChem 20110606

• Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation.

  The Journal of biological chemistry 20110603

• A review of pharmacologic options for previously untreated chronic lymphocytic leukemia.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110601

• Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue.

  Clinical oral investigations 20110601

• Homochiral selectivity in RNA synthesis: montmorillonite-catalyzed quaternary reactions of D, L-purine with D, L- pyrimidine nucleotides.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20110601

• Low-molecular-mass purine nucleoside phosphorylase: characterization and application in enzymatic synthesis of nucleoside antiviral drugs.

  Biotechnology letters 20110601

• Microbial community and metabolomic comparison of irritable bowel syndrome faeces.

  Journal of medical microbiology 20110601

• N9-substituted derivatives of kinetin: effective anti-senescence agents.

  Phytochemistry 20110601

• Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.

  Cancer gene therapy 20110601

• Mutational analysis of the major soybean UreF paralogue involved in urease activation.

  Journal of experimental botany 20110601

• A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster.

  Genetics 20110601

• Implications of minimal residual disease in hairy cell leukemia after cladribine using immunohistochemistry and immunophenotyping.

  Leukemia & lymphoma 20110601

• Purine analog toxicity in patients with hairy cell leukemia.

  Leukemia & lymphoma 20110601

• Characterization of mitochondrial mRNAs in codfish reveals unique features compared to mammals.

  Current genetics 20110601

• Infectious complications in hairy cell leukemia.

  Leukemia & lymphoma 20110601

• Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence.

  Leukemia & lymphoma 20110601

• A patient's point of view.

  Leukemia & lymphoma 20110601

• Nucleotide promiscuity of 3-phosphoglycerate kinase is in focus: implications for the design of better anti-HIV analogues.

  Molecular bioSystems 20110601

• Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.

  Diabetes 20110601

• Nucleotide receptors as targets in the pharmacological enhancement of dermal wound healing.

  Purinergic signalling 20110601

• Purine metabolism, immune reconstitution, and abdominal adipose tumor after gene therapy for adenosine deaminase deficiency.

  The Journal of allergy and clinical immunology 20110601

• Synthesis and antimycobacterial activities of non-purine analogs of 6-aryl-9-benzylpurines: Imidazopyridines, pyrrolopyridines, benzimidazoles, and indoles.

  Bioorganic & medicinal chemistry 20110601

• Allopurinol, uric acid, and oxidative stress in cardiorenal disease.

  International urology and nephrology 20110601

• Long-term results for pentostatin and cladribine treatment of hairy cell leukemia.

  Leukemia & lymphoma 20110601

• Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.

  Leukemia & lymphoma 20110601

• Management of hairy cell leukemia variant.

  Leukemia & lymphoma 20110601

• Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia.

  Leukemia & lymphoma 20110601

• Molecular variant of hairy cell leukemia with poor prognosis.

  Leukemia & lymphoma 20110601

• Effects of feeding different levels of dietary fiber through the addition of corn stover on nutrient utilization of dairy heifers precision-fed high and low concentrate diets.

  Journal of dairy science 20110601

• Introductory overview of purinergic signalling.

  Frontiers in bioscience (Elite edition) 20110601

• Purinoceptors in inflammation: potential as anti-inflammatory therapeutic targets.

  Frontiers in bioscience (Landmark edition) 20110601

• Differences in dinucleotide frequencies of thermophilic genes encoding water soluble and membrane proteins.

  Journal of Zhejiang University. Science. B 20110601

• Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors.

  Current medicinal chemistry 20110601

• The genetic basis of panic disorder.

  Journal of Korean medical science 20110601

• The therapeutic potential of adenosine triphosphate as an immune modulator in the treatment of HIV/AIDS: a combination approach with HAART.

  Current HIV research 20110601

• A new view of the bacterial cytosol environment.

  PLoS computational biology 20110601

• A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.

  PLoS genetics 20110601

• Pathways of distinction analysis: a new technique for multi-SNP analysis of GWAS data.

  PLoS genetics 20110601

• Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles in rheumatoid arthritis.

  Frontiers of medicine 20110601

• 1-Acetyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one.

  Acta crystallographica. Section E, Structure reports online 20110601

• 7,9-Bis(hy-droxy-meth-yl)-7H-purine-2,6,8(1H,3H,9H)trione.

  Acta crystallographica. Section E, Structure reports online 20110601

• Animal models of intellectual disability: towards a translational approach.

  Clinics (Sao Paulo, Brazil) 20110601

• Novel mutations in the human HPRT gene.

  Nucleosides, nucleotides & nucleic acids 20110601

• [Mycophenolate mofetil as a novel treatment for lupus nephritis].

  Harefuah 20110601

• Gammaretroviral vectors: biology, technology and application.

  Viruses 20110601

• 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues?

  Toxins 20110601

• Nuclear Factor κB and Adenosine Receptors: Biochemical and Behavioral Profiling.

  Current neuropharmacology 20110601

• The utility of uric acid assay in dogs as an indicator of functional hepatic mass.

  Journal of the South African Veterinary Association 20110601

• [Bioinformatics analysis of nicotinamide phosphoribosyl transferase of Schistosoma japonicum].

  Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control 20110601

• Toxicological pathology in the rat placenta.

  Journal of toxicologic pathology 20110601

• Identification of epigenetic regulators of a transcriptionally silenced transgene in maize.

  G3 (Bethesda, Md.) 20110601

• RCL hydrolyzes 2'-deoxyribonucleoside 5'-monophosphate via formation of a reaction intermediate.

  Biochemistry 20110531

• Treponema denticola PurE Is a bacterial AIR carboxylase.

  Biochemistry 20110531

• Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110527

• Contiguous metal-mediated base pairs comprising two Ag(I) ions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110527

• Kinetic mechanism for the excision of hypoxanthine by Escherichia coli AlkA and evidence for binding to DNA ends.

  Biochemistry 20110524

• Palladium-catalyzed C-H bond functionalization of C6-arylpurines.

  Chemical communications (Cambridge, England) 20110521

• Presence of divalent cation is not mandatory for the formation of intramolecular purine-motif triplex containing human c-jun protooncogene target.

  Biochemistry 20110517

• Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.

  Biochemistry 20110517

• (5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coli.

  Biochemistry 20110517

• Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress.

  Biochemical pharmacology 20110515

• NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions.

  Biochemistry 20110510

• A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling.

  British journal of cancer 20110510

• Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism.

  Journal of proteome research 20110506

• Combined metabonomic and quantitative real-time PCR analyses reveal systems metabolic changes of Fusarium graminearum induced by Tri5 gene deletion.

  Journal of proteome research 20110506

• Synthesis of 2'-O-[2-(N-methylcarbamoyl)ethyl]ribonucleosides using oxa-Michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides.

  The Journal of organic chemistry 20110506

• Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells.

  Enzyme and microbial technology 20110506

• Caffeine and uric acid mediate glutathione synthesis for neuroprotection.

  Neuroscience 20110505

• Identification and characterization of small-molecule inducers of fetal hemoglobin.

  ChemMedChem 20110502

• Stability and structure of mixed-ligand metal ion complexes that contain Ni2+, Cu2+, or Zn2+, and Histamine, as well as adenosine 5'-triphosphate (ATP4-) or uridine 5'-triphosphate (UTP(4-): an intricate network of equilibria.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110502

• Six-month repeated dose toxicity of orally administered metacavir in rhesus monkeys.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110501

• Pharmacokinetics of clofarabine in patients with high-risk inherited metabolic disorders undergoing brain-sparing hematopoietic cell transplantation.

  Journal of clinical pharmacology 20110501

• Identification of a 2-cell stage specific inhibitor of the cleavage of preimplantation mouse embryos synthesized by rat hepatoma cells as 5'-deoxy-5'-methylthioadenosine.

  Zygote (Cambridge, England) 20110501

• Adenosine receptors and cancer.

  Biochimica et biophysica acta 20110501

• Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.

  Archives of toxicology 20110501

• Hematopoietic stem cell mobilization with the reversible CXCR4 receptor inhibitor plerixafor (AMD3100)-Polish compassionate use experience.

  Annals of hematology 20110501

• Metabolomic changes in autopsy-confirmed Alzheimer's disease.

  Alzheimer's & dementia : the journal of the Alzheimer's Association 20110501

• Adenosine and its receptors in the heart: regulation, retaliation and adaptation.

  Biochimica et biophysica acta 20110501

• The pentostatin plus cyclophosphamide nonmyeloablative regimen induces durable host T cell functional deficits and prevents murine marrow allograft rejection.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501

• Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

  Molecular and biochemical parasitology 20110501

• Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production.

  The Journal of general virology 20110501

• A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart.

  Basic research in cardiology 20110501

• Akt, 14-3-3ζ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma.

  Leukemia & lymphoma 20110501

• Beyond glucose: metabolic shifts in responses to the effects of the oral glucose tolerance test and the high-fructose diet in rats.

  Molecular bioSystems 20110501

• Identification of the UMP synthase gene by establishment of uracil auxotrophic mutants and the phenotypic complementation system in the marine diatom Phaeodactylum tricornutum.

  Plant physiology 20110501

• The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus.

  The Journal of antimicrobial chemotherapy 20110501

• Managing MS in a changing treatment landscape.

  Journal of neurology 20110501

• Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501

• Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group.

  Leukemia & lymphoma 20110501

• Uridine correlates with the concentration of fructosamine and HbA1c in children with type 1 diabetes.

  Acta paediatrica (Oslo, Norway : 1992) 20110501

• Educational paper. The expanding clinical and immunological spectrum of severe combined immunodeficiency.

  European journal of pediatrics 20110501

• Waldenström macroglobulinemia: 2011 update on diagnosis, risk stratification, and management.

  American journal of hematology 20110501

• Molecular cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of a purine nucleoside phosphorylase from Bacillus subtilis strain 168.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110501

• Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone.

  Inhalation toxicology 20110501

• Crystal structures of T. b. rhodesiense adenosine kinase complexed with inhibitor and activator: implications for catalysis and hyperactivation.

  PLoS neglected tropical diseases 20110501

• Genetic variation in genes involved in folate and drug metabolism in a south Indian population.

  Indian journal of human genetics 20110501

• Foamy virus biology and its application for vector development.

  Viruses 20110501

• Postoperative care of the transplanted patient.

  Current cardiology reviews 20110501

• Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays.

  Biochemistry 20110426

• Inhibition by purine nucleotides of the release of reactive oxygen species from muscle mitochondria: indication for a function of uncoupling proteins as superoxide anion transporters.

  Biochemical and biophysical research communications 20110422

• Local excitation of the 5-bromouracil chromophore in DNA. Computational and UV spectroscopic studies.

  The journal of physical chemistry. B 20110421

• Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110420

• Synthesis of fluorinated purine and 1-deazapurine glycosides as potential inhibitors of adenosine deaminase.

  The Journal of organic chemistry 20110415

• Pd(II)-catalyzed ortho arylation of 6-arylpurines with aryl iodides via purine-directed C-H activation: a new strategy for modification of 6-arylpurine derivatives.

  Organic letters 20110415

• Design, synthesis, and evaluation of small molecule Hsp90 probes.

  Bioorganic & medicinal chemistry 20110415

• Coumarin-purine ribofuranoside conjugates as new agents against hepatitis C virus.

  Journal of medicinal chemistry 20110414

• Structure of mammalian AMPK and its regulation by ADP.

  Nature 20110414

• Effects of Mg2+ on the free energy landscape for folding a purine riboswitch RNA.

  Biochemistry 20110412

• Phenotypes and circadian rhythm in utilization of formate in purine nucleotide biosynthesis de novo in adult humans.

  Life sciences 20110411

• Fabrication of a bilayer potentiometric phosphate biosensor by cross-link immobilization with bovine serum albumin and glutaraldehyde.

  Analytica chimica acta 20110408

• 7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine.

  Organic & biomolecular chemistry 20110407

• Computational design of ring-expanded pyrimidine-based DNA motifs with improved conductivity.

  Physical chemistry chemical physics : PCCP 20110407

• Microwave promoted C6-alkylation of purines through S(N)Ar-based reaction of 6-chloropurines with 3-alkyl-acetylacetone.

  Organic & biomolecular chemistry 20110407

• Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylase.

  Biochemistry 20110405

• Pentostatin for treatment of steroid-refractory acute GVHD: a retrospective single-center analysis.

  Bone marrow transplantation 20110401

• Proper laboratory notebook practices: protecting your intellectual property.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401

• Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production.

  Amino acids 20110401

• Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase.

  Glycobiology 20110401

• Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway.

  European journal of nuclear medicine and molecular imaging 20110401

• Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis.

  Plant physiology 20110401

• Breast fine-needle aspiration malondialdehyde deoxyguanosine adduct in breast cancer.

  Free radical research 20110401

• Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia.

  Molecular bioSystems 20110401

• The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA.

  Journal of psychopharmacology (Oxford, England) 20110401

• Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties.

  The Journal of biological chemistry 20110401

• Role of insert-1 of myosin VI in modulating nucleotide affinity.

  The Journal of biological chemistry 20110401

• Spectroscopy study on the noncovalent interactions in the binary and ternary systems of L-lysine, adenosine 5'-triphosphate and magnesium ions.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110401

• Photosensitizer-doped conjugated polymer nanoparticles with high cross-sections for one- and two-photon excitation.

  Nanoscale 20110401

• Recombinant Escherichia coli GMP reductase: kinetic, catalytic and chemical mechanisms, and thermodynamics of enzyme-ligand binary complex formation.

  Molecular bioSystems 20110401

• Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies.

  Cancer biology & therapy 20110401

• Purinergic signaling in neural development.

  Seminars in cell & developmental biology 20110401

• Neuroglial interactions mediated by purinergic signalling in the pathophysiology of CNS disorders.

  Seminars in cell & developmental biology 20110401

• Dynamic metabonomic responses of tobacco (Nicotiana tabacum) plants to salt stress.

  Journal of proteome research 20110401

• Synthesis of purin-2-yl and purin-6-yl-aminoglucitols as C-nucleosidic ATP mimics and biological evaluation as FGFR3 inhibitors.

  European journal of medicinal chemistry 20110401

• Enzymatic activity of the soybean ecto-apyrase GS52 is essential for stimulation of nodulation.

  Plant physiology 20110401

• Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome.

  Diabetes 20110401

• ATP: a ubiquitous gliotransmitter integrating neuron-glial networks.

  Seminars in cell & developmental biology 20110401

• The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects.

  Current topics in medicinal chemistry 20110401

• Nitrogen partitioning and isotopic fractionation in dairy cows consuming diets based on a range of contrasting forages.

  Journal of dairy science 20110401

• Synthesis and antiviral activity of N9-[3-fluoro-2-(phosphonomethoxy)propyl] analogues derived from N6-substituted adenines and 2,6-diaminopurines.

  Bioorganic & medicinal chemistry 20110401

• Simultaneous determination of 5'-monophosphate nucleotides in infant formulas by HPLC-MS.

  Journal of chromatographic science 20110401

• The complete chloroplast genome of 17 individuals of pest species Jacobaea vulgaris: SNPs, microsatellites and barcoding markers for population and phylogenetic studies.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20110401

• [Autoimmune haemolytic anemia: diagnosis strategy and new treatments].

  Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20110401

• Formation of nucleobases from formamide in the presence of iron oxides: implication in chemical evolution and origin of life.

  Astrobiology 20110401

• Deep UV resonant Raman spectroscopy for photodamage characterization in cells.

  Biomedical optics express 20110401

• Characterization of schistosome tegumental alkaline phosphatase (SmAP).

  PLoS neglected tropical diseases 20110401

• High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase.

  PLoS neglected tropical diseases 20110401

• Intermolecular interaction between a branching ribozyme and associated homing endonuclease mRNA.

  Biological chemistry 20110401

• In silico elucidation of the recognition dynamics of ubiquitin.

  PLoS computational biology 20110401

• Fluctuations in spo0A transcription control rare developmental transitions in Bacillus subtilis.

  PLoS genetics 20110401

• Metabolism of microbial nitrogen in ruminants with special reference to nucleic acids.

  Animal science journal = Nihon chikusan Gakkaiho 20110401

• Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity.

  Diabetes & metabolism journal 20110401

• [The role of uric acid in heart failure].

  Revista medica de Chile 20110401

• Effects of low dose methotrexate on relapsing-remitting multiple sclerosis in comparison to Interferon β-1α: A randomized controlled trial.

  Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110401

• In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization.

  Physical chemistry chemical physics : PCCP 20110328

• New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.

  Journal of natural products 20110325

• Novel ligands for a purine riboswitch discovered by RNA-ligand docking.

  Chemistry & biology 20110325

• Xanthine dehydrogenase electrocatalysis: autocatalysis and novel activity.

  The journal of physical chemistry. B 20110324

• Nucleoside transport inhibitors: structure-activity relationships for pyrimido[5,4-d]pyrimidine derivatives that potentiate pemetrexed cytotoxicity in the presence of α1-acid glycoprotein.

  Journal of medicinal chemistry 20110324

• Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase.

  Biochemistry 20110322

• A high-affinity adenosine kinase from Anopheles gambiae.

  Biochemistry 20110322

• Metabolic fate of fumarate, a side product of the purine salvage pathway in the intraerythrocytic stages of Plasmodium falciparum.

  The Journal of biological chemistry 20110318

• Simultaneous detection of guanine, adenine, thymine and cytosine at choline monolayer supported multiwalled carbon nanotubes film.

  Biosensors & bioelectronics 20110315

• Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.

  Cancer research 20110315

• Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants.

  Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110311

• Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl transferase. Application in electrochemical DNA hybridization and protein-DNA binding assays.

  Organic & biomolecular chemistry 20110307

• Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy.

  Organic & biomolecular chemistry 20110307

• Comprehensive proteomic analysis of the effects of purine analogs on human Raji B-cell lymphoma.

  Journal of proteome research 20110304

• Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation.

  The EMBO journal 20110302

• Allopurinol and xanthine oxidase inhibition in liver ischemia reperfusion.

  Journal of hepato-biliary-pancreatic sciences 20110301

• Initiation of translation at an upstream non-AUG codon accounting for N-terminally extended minor forms of recombinant proteins expressed in insect cells.

  Protein expression and purification 20110301

• In vivo methods to study uptake of nanoparticles into the brain.

  Pharmaceutical research 20110301

• Modulation of circulating purines and pyrimidines by physical exercise in the horse.

  European journal of applied physiology 20110301

• DNA strand breaks and base modifications induced by cholesterol hydroperoxides.

  Free radical research 20110301

• Purification, characterization, and cloning of a bifunctional molybdoenzyme with hydratase and alcohol dehydrogenase activity.

  Applied microbiology and biotechnology 20110301

• Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines.

  Biochemical pharmacology 20110301

• Gout and hyperuricemia in young people.

  Current opinion in rheumatology 20110301

• Germline copy number variations in BRCA1-associated ovarian cancer patients.

  Genes, chromosomes & cancer 20110301

• Purine 5',8-cyclonucleoside lesions: chemistry and biology.

  Chemical Society reviews 20110301

• Characterization of the B6.61 polymerase ribozyme accessory domain.

  RNA (New York, N.Y.) 20110301

• Strict 3' splice site sequence requirements for U2 snRNP recruitment after U2AF binding underlie a genetic defect leading to autoimmune disease.

  RNA (New York, N.Y.) 20110301

• Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair.

  Biochemistry 20110301

• Arabidopsis nucleoside hydrolases involved in intracellular and extracellular degradation of purines.

  The Plant journal : for cell and molecular biology 20110301

• Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity.

  Cancer research 20110301

• Enhanced expression of recX in Mycobacterium tuberculosis owing to a promoter internal to recA.

  Tuberculosis (Edinburgh, Scotland) 20110301

• Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells.

  Nature chemical biology 20110301

• Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.

  Molecular cancer therapeutics 20110301

• New nucleoside analogs for patients with hematological malignancies.

  Expert opinion on investigational drugs 20110301

• Optimal pharmacotherapeutic management of chronic lymphocytic leukaemia: considerations in the elderly.

  Drugs & aging 20110301

• Febuxostat for treatment of chronic gout.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110301

• The effect of the feed-to-buffer ratio on bacterial diversity and ruminal fermentation in single-flow continuous-culture fermenters.

  Journal of dairy science 20110301

• Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.

  Diabetes 20110301

• Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation.

  Arthritis and rheumatism 20110301

• The effects of intraoperative adenosine infusion on acute opioid tolerance and opioid induced hyperalgesia induced by remifentanil in adult patients undergoing tonsillectomy.

  The Korean journal of pain 20110301

• The relationship between normal serum uric acid and nonalcoholic fatty liver disease.

  Journal of Korean medical science 20110301

• Urea metabolism in plants.

  Plant science : an international journal of experimental plant biology 20110301

• The Staphylococcus aureus RNome and its commitment to virulence.

  PLoS pathogens 20110301

• Towards personalized medicine - the role of methotrexate.

  The Indian journal of medical research 20110301

• Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians.

  The Indian journal of medical research 20110301

• A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis.

  PLoS biology 20110301

• Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells.

  PLoS computational biology 20110301

• Reconciliation of genome-scale metabolic reconstructions for comparative systems analysis.

  PLoS computational biology 20110301

• The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.

  PLoS genetics 20110301

• Second annual UK Purine Club Symposium report 2010.

  Purinergic signalling 20110301

• UK Purine Club 2010 Abstracts.

  Purinergic signalling 20110301

• 6-Chloro-9-(2-nitro-phenyl-sulfon-yl)-9H-purine.

  Acta crystallographica. Section E, Structure reports online 20110301

• Differential gene expression in the nucleus accumbens and frontal cortex of lewis and Fischer 344 rats relevant to drug addiction.

  Current neuropharmacology 20110301

• Role of ribose deficit in rat testicular metabolism under conditions of overtraining.

  Bulletin of experimental biology and medicine 20110301

• Guidelines for the management of bacterial and fungal infections during chemotherapy for pediatric acute leukemia or solid tumors: what is available in 2010?

  Pediatric reports 20110224

• Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing.

  Biochemistry 20110222

• Trifunctionalization of the purine scaffold using Mg and Zn organometallic intermediates.

  Organic letters 20110218

• Determination of uric acid and creatinine in human urine using hydrophilic interaction chromatography.

  Talanta 20110215

• Modern strategies for hairy cell leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210

• Ionization of purine tautomers in nucleobases, nucleosides, and nucleotides: from the gas phase to the aqueous environment.

  The journal of physical chemistry. B 20110210

• Chemical shift tensors in isomers of adenine: relation to aromaticity of purine rings?

  Chemphyschem : a European journal of chemical physics and physical chemistry 20110207

• Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein.

  The Journal of biological chemistry 20110204

• Energetically important C-H···F-C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity.

  Journal of the American Chemical Society 20110202

• Hairy-cell leukemia variant: recent view on diagnosis, biology and treatment.

  Cancer treatment reviews 20110201

• Prognostic value of xanthine oxidoreductase expression in patients with non-small cell lung cancer.

  Lung cancer (Amsterdam, Netherlands) 20110201

• Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia.

  Annals of hematology 20110201

• β-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons.

  Gastroenterology 20110201

• Endogenous fraction and urinary recovery of purine derivatives obtained by different methods in Nellore cattle.

  Journal of animal science 20110201

• Purine analog for the prevention of postoperative recurrence of Crohn's disease: is it really better?

  Inflammatory bowel diseases 20110201

• Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source.

  Microbiology (Reading, England) 20110201

• The hydrolysis of striatal adenine- and guanine-based purines in a 6-hydroxydopamine rat model of Parkinson's disease.

  Neurochemical research 20110201

• Purine receptor-mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex.

  British journal of pharmacology 20110201

• Cladribine combined with rituximab (R-2-CdA) therapy is an effective salvage therapy in relapsed or refractory indolent B-cell non-Hodgkin lymphoma.

  European journal of haematology 20110201

• Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice.

  Aging cell 20110201

• The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae.

  The Journal of general virology 20110201

• Effects of molybdenum deficiency and defects in molybdate transporter MOT1 on transcript accumulation and nitrogen/sulphur metabolism in Arabidopsis thaliana.

  Journal of experimental botany 20110201

• Plasticity in the purine-thiamine metabolic network of Salmonella.

  Genetics 20110201

• Urinary stone composition in pediatric patients: a retrospective study of 205 cases.

  Clinical chemistry and laboratory medicine 20110201

• Reactivation of meristem activity and sprout growth in potato tubers require both cytokinin and gibberellin.

  Plant physiology 20110201

• Results of a phase II study of pemetrexed as first-line chemotherapy in patients with advanced or metastatic breast cancer.

  Breast cancer research and treatment 20110201

• Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP.

  Endocrinology 20110201

• Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell.

  EMBO molecular medicine 20110201

• Hairy cell leukemia and variant in Taiwan: report of a variant case and literature review.

  International journal of clinical and experimental pathology 20110201

• Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities.

  Expert review of anti-infective therapy 20110201

• [A case of chronic myeloid leukemia occurring during treatment for chronic lymphocytic leukemia].

  Gan to kagaku ryoho. Cancer & chemotherapy 20110201

• Deoxycytidine production by metabolically engineered Corynebacterium ammoniagenes.

  Journal of microbiology (Seoul, Korea) 20110201

• Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain.

  PLoS computational biology 20110201

• p73 as a pharmaceutical target for cancer therapy.

  Current pharmaceutical design 20110201

• Adeninium perchlorate.

  Acta crystallographica. Section E, Structure reports online 20110201

• 1-{4-Chloro-2-[2-(2-fluoro-phen-yl)-1,3-dithio-lan-2-yl]phen-yl}-2-methyl-1H-imidazole-5-carbaldehyde.

  Acta crystallographica. Section E, Structure reports online 20110201

• Metabolomics as a powerful tool for molecular quality assessment of the fish Sparus aurata.

  Nutrients 20110201

• Genotoxic evaluation of the non-halogenated disinfection by-products nitrosodimethylamine and nitrosodiethylamine.

  Journal of hazardous materials 20110130

• A feedback circuit between transcriptional activation and self-destruction of Gcn4 separates its metabolic and morphogenic response in diploid yeasts.

  Journal of molecular biology 20110128

• Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosis.

  Biochemistry 20110125

• Active-site structure of class IV adenylyl cyclase and transphyletic mechanism.

  Journal of molecular biology 20110121

• Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease.

  The Cochrane database of systematic reviews 20110119

• UMP kinase from Mycobacterium tuberculosis: Mode of action and allosteric interactions, and their likely role in pyrimidine metabolism regulation.

  Archives of biochemistry and biophysics 20110115

• The dynamics of single spike-evoked adenosine release in the cerebellum.

  The Journal of physiology 20110115

• Identifying cancer driver genes in tumor genome sequencing studies.

  Bioinformatics (Oxford, England) 20110115

• Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.

  Journal of medicinal chemistry 20110113

• Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.

  Journal of medicinal chemistry 20110113

• Computational biology for ageing.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20110112

• Evidence for a near-resonant charge transfer mechanism for double-stranded peptide nucleic acid.

  Journal of the American Chemical Society 20110112

• [Effect of dantrolene on energy metabolism in rats with myocardial ischemia-reperfusion].

  Zhonghua yi xue za zhi 20110111

• Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn 'southern' ribose conformation underlies activity at the sea urchin cADPR receptor.

  Organic & biomolecular chemistry 20110107

• Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity.

  The Journal of biological chemistry 20110107

• Regulation of ENT1 expression and ENT1-dependent nucleoside transport by c-Jun N-terminal kinase.

  Biochemical and biophysical research communications 20110107

• Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.

  British journal of cancer 20110104

• Purinergic activation of dorsal root ganglion neurones in vivo.

  Neuroscience letters 20110103

• N-methylpurines are heterogeneously repaired in human mitochondria but not evidently repaired in yeast mitochondria.

  DNA repair 20110102

• A rapid and simple chemiluminescence method for screening levels of inosine and hypoxanthine in non-traumatic chest pain patients.

  Luminescence : the journal of biological and chemical luminescence 20110101

• The use of tropical protein-rich leaves as supplements to Thai swamp buffalo receiving a basal diet of rice straw and treated leucaena (Leucaena leucocephala).

  Tropical animal health and production 20110101

• A Bayesian approach for fast and accurate gene tree reconstruction.

  Molecular biology and evolution 20110101

• Ubiquinol (QH(2)) functions as a negative regulator of purine nucleotide inhibition of Acanthamoeba castellanii mitochondrial uncoupling protein.

  Biochimica et biophysica acta 20110101

• Enhancement of extracellular purine nucleoside accumulation by Bacillus strains through genetic modifications of genes involved in nucleoside export.

  Journal of industrial microbiology & biotechnology 20110101

• Distribution, biosynthesis and catabolism of methylxanthines in plants.

  Handbook of experimental pharmacology 20110101

• Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds.

  Handbook of experimental pharmacology 20110101

• Evidence of feminization in wild Elliptio complanata mussels in the receiving waters downstream of a municipal effluent outfall.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110101

• Molecular characterization of the AdeI mutant of Chinese hamster ovary cells: a cellular model of adenylosuccinate lyase deficiency.

  Molecular genetics and metabolism 20110101

• Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2.

  Microbiology (Reading, England) 20110101

• Characterization of amplicons that suppress the conditional lethal growth phenotype of a Leishmania donovani mutant lacking normal purine salvage mechanisms.

  Molecular and biochemical parasitology 20110101

• A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20110101

• Brassinolide-improved development of Brassica napus microspore-derived embryos is associated with increased activities of purine and pyrimidine salvage pathways.

  Planta 20110101

• Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2',(3')-substituted purine and pyrimidine nucleotides.

  The Journal of pharmacology and experimental therapeutics 20110101

• Biological Evaluation of Polyherbal Ayurvedic Cardiotonic Preparation 'Mahamrutyunjaya rasa'.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response.

  Arthritis and rheumatism 20110101

• The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients.

  Advances in hematology 20110101

• Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer.

  Journal of biomedicine & biotechnology 20110101

• Genetic association mapping identifies single nucleotide polymorphisms in genes that affect abscisic acid levels in maize floral tissues during drought.

  Journal of experimental botany 20110101

• Comparative proteomic and genetic analyses reveal unidentified mutations in Escherichia coli XL1-Blue and DH5α.

  FEMS microbiology letters 20110101

• A population study of Lesch-Nyhan disease in the UK.

  Developmental medicine and child neurology 20110101

• Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.

  Bioorganic & medicinal chemistry 20110101

• The role of system-specific molecular chaperones in the maturation of molybdoenzymes in bacteria.

  Biochemistry research international 20110101

• Relative similarity within purine nucleotide and ligand structures operating on nitric oxide synthetase, guanylyl cyclase and potassium (K ATP, BK Ca) channels.

  The Journal of pharmacy and pharmacology 20110101

• Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.

  Journal of synchrotron radiation 20110101

• Geometric properties of nucleic acids with potential for autobuilding.

  Acta crystallographica. Section A, Foundations of crystallography 20110101

• R2R--software to speed the depiction of aesthetic consensus RNA secondary structures.

  BMC bioinformatics 20110101

• HPLC analysis for the clinical-biochemical diagnosis of inborn errors of metabolism of purines and pyrimidines.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Impact of Alu repeats on the evolution of human p53 binding sites.

  Biology direct 20110101

• The substrate binding preferences of Plasmodium thymidylate kinase.

  Biological & pharmaceutical bulletin 20110101

• Antimicrobial and antineoplastic activities of agelasine analogs modified in the purine 2-position.

  Archiv der Pharmazie 20110101

• Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae.

  Microbial cell factories 20110101

• A proteomic analysis of C-reactive protein stimulated THP-1 monocytes.

  Proteome science 20110101

• Implementation of a new cost efficacy method for blood irradiation using a non dedicated device.

  Journal of experimental & clinical cancer research : CR 20110101

• Uptake of AMP, ADP, and ATP in Escherichia coli W.

  Bioscience, biotechnology, and biochemistry 20110101

• Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment.

  BMC medicine 20110101

• Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?

  International journal of biological sciences 20110101

• Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.

  Parkinson's disease 20110101

• Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors.

  Silence 20110101

• Gadd45a is an RNA binding protein and is localized in nuclear speckles.

  PloS one 20110101

• Liposarcoma: molecular genetics and therapeutics.

  Sarcoma 20110101

• Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells.

  Cell communication and signaling : CCS 20110101

• Small RNAs in the genus Clostridium.

  mBio 20110101

• Removal of PCR error products and unincorporated primers by metal-chelate affinity chromatography.

  PloS one 20110101

• Distinctive mitochondrial genome of Calanoid copepod Calanus sinicus with multiple large non-coding regions and reshuffled gene order: useful molecular markers for phylogenetic and population studies.

  BMC genomics 20110101

• Uric acid as a predictor of all-cause mortality in heart failure: a meta-analysis.

  Congestive heart failure (Greenwich, Conn.) 20110101

• Label-free peptide profiling of Orbitrap™ full mass spectra.

  BMC research notes 20110101

• Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases.

  Journal of biomedicine & biotechnology 20110101

• Evolution of major milk proteins in Mus musculus and Mus spretus mouse species: a genoproteomic analysis.

  BMC genomics 20110101

• Flux balance analysis of ammonia assimilation network in E. coli predicts preferred regulation point.

  PloS one 20110101

• It takes two to tango: defining an essential second active site in pyridoxal 5'-phosphate synthase.

  PloS one 20110101

• Transcriptomic signatures of ash (Fraxinus spp.) phloem.

  PloS one 20110101

• Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms.

  PLoS genetics 20110101

• Exploiting Statistical Methodologies and Controlled Vocabularies for Prioritized Functional Analysis of Genomic Experiments: the StRAnGER Web Application.

  Frontiers in neuroscience 20110101

• A genome-wide association study of serum uric acid in African Americans.

  BMC medical genomics 20110101

• Hypoxic regulation of glycosylation via the N-acetylglucosamine cycle.

  Journal of clinical biochemistry and nutrition 20110101

• Nucleotides function as endogenous chemical sensors for oxidative stress signaling.

  Journal of clinical biochemistry and nutrition 20110101

• Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury.

  Journal of biomedical science 20110101

• FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90Yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases.

  Journal of experimental & clinical cancer research : CR 20110101

• [The first case of adenine phosphoribosyltransferase deficiency with APRT Q0 (M1V) mutation in Japan].

  Hinyokika kiyo. Acta urologica Japonica 20110101

• Bacillus subtilis two-component system sensory kinase DegS is regulated by serine phosphorylation in its input domain.

  PloS one 20110101

• Simple structural differences between coding and noncoding DNA.

  PloS one 20110101

• Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota.

  PloS one 20110101

• HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?

  PloS one 20110101

• Genomic organization and splicing evolution of the doublesex gene, a Drosophila regulator of sexual differentiation, in the dengue and yellow fever mosquito Aedes aegypti.

  BMC evolutionary biology 20110101

• Challenges of ligand identification for riboswitch candidates.

  RNA biology 20110101

• Lysyl oxidase, a critical intra- and extra-cellular target in the lung for cigarette smoke pathogenesis.

  International journal of environmental research and public health 20110101

• Potential of immunosuppressive agents in cerebral ischaemia.

  The Indian journal of medical research 20110101

• Staphylococcus aureus seroproteomes discriminate ruminant isolates causing mild or severe mastitis.

  Veterinary research 20110101

• Proteome analyses of cellular proteins in methicillin-resistant Staphylococcus aureus treated with rhodomyrtone, a novel antibiotic candidate.

  PloS one 20110101

• SOD2 deficient erythroid cells up-regulate transferrin receptor and down-regulate mitochondrial biogenesis and metabolism.

  PloS one 20110101

• Effect of attC structure on cassette excision by integron integrases.

  Mobile DNA 20110101

• Simulated evolution applied to study the genetic code optimality using a model of codon reassignments.

  BMC bioinformatics 20110101

• Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: Evidence from purine biosensors and P2 receptor agonists and antagonists.

  Neuropharmacology 20110101

• Role of rituximab in first-line treatment of chronic lymphocytic leukemia.

  Therapeutics and clinical risk management 20110101

• On origin of genetic code and tRNA before translation.

  Biology direct 20110101

• The G protein-coupled receptors in the pufferfish Takifugu rubripes.

  BMC bioinformatics 20110101

• iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis.

  BMC bioinformatics 20110101

• Unfolded protein response in cancer: the physician's perspective.

  Journal of hematology & oncology 20110101

• Alanine zipper-like coiled-coil domains are necessary for homotypic dimerization of plant GAGA-factors in the nucleus and nucleolus.

  PloS one 20110101

• Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences.

  Fluids and barriers of the CNS 20110101

• Complementary effects of extracellular nucleotides and platelet-derived extracts on angiogenesis of vasa vasorum endothelial cells in vitro and subcutaneous Matrigel plugs in vivo.

  Vascular cell 20110101

• Multi-omics approach to study the growth efficiency and amino acid metabolism in Lactococcus lactis at various specific growth rates.

  Microbial cell factories 20110101

• Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds.

  BMC genomics 20110101

• Gene expression throughout a vertebrate's embryogenesis.

  BMC genomics 20110101

• Bacillus anthracis spore interactions with mammalian cells: relationship between germination state and the outcome of in vitro.

  BMC microbiology 20110101

• The human serum metabolome.

  PloS one 20110101

• High throughput nano-liter RT-qPCR to classify soil contamination using a soil arthropod.

  BMC molecular biology 20110101

• Multiple invasions into freshwater by pufferfishes (teleostei: tetraodontidae): a mitogenomic perspective.

  PloS one 20110101

• Molecular dynamics simulations of protein targets identified in Mycobacterium tuberculosis.

  Current medicinal chemistry 20110101

• Purine Salvage Pathway in Mycobacterium tuberculosis.

  Current medicinal chemistry 20110101

• Novel sulI binary vectors enable an inexpensive foliar selection method in Arabidopsis.

  BMC research notes 20110101

• Bioinformatics analysis of disordered proteins in prokaryotes.

  BMC bioinformatics 20110101

• Alternative TFAP2A isoforms have distinct activities in breast cancer.

  Breast cancer research : BCR 20110101

• [Preliminary study on molecular mechanism of lotus mutants induced by ion implantation].

  Yi chuan = Hereditas 20110101

• Antiproliferative property of hexadecyloxypropyl 9-[2-(phosphonomethoxy) ethyl] guanine (HDP-PMEG) for unwanted ocular proliferation.

  Molecular vision 20110101

• New implications on genomic adaptation derived from the Helicobacter pylori genome comparison.

  PloS one 20110101

• The PI3K p110δ regulates expression of CD38 on regulatory T cells.

  PloS one 20110101

• Molecular biology of nucleoside transporters and their distributions and functions in the brain.

  Current topics in medicinal chemistry 20110101

• Neurological disorders of purine and pyrimidine metabolism.

  Current topics in medicinal chemistry 20110101

• Metabolic network of nucleosides in the brain.

  Current topics in medicinal chemistry 20110101

• Genome wide SNP discovery, analysis and evaluation in mallard (Anas platyrhynchos).

  BMC genomics 20110101

• Sequential analysis of global gene expression profiles in immature and in vitro matured bovine oocytes: potential molecular markers of oocyte maturation.

  BMC genomics 20110101

• Cyclosporine A for chemotherapy-resistant subcutaneous panniculitis-like T cell lymphoma with hemophagocytic syndrome.

  Acta haematologica 20110101

• Expression of Drosophila adenosine deaminase in immune cells during inflammatory response.

  PloS one 20110101

• Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.

  Genome biology 20110101

• Across bacterial phyla, distantly-related genomes with similar genomic GC content have similar patterns of amino acid usage.

  PloS one 20110101

• The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors.

  Current medicinal chemistry 20110101

• Tegument protein control of latent herpesvirus establishment and animation.

  Herpesviridae 20110101

• Importance of phenols structure on their activity as antinitrosating agents: A kinetic study.

  Journal of pharmacy & bioallied sciences 20110101

• One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.

  Journal of biomedicine & biotechnology 20110101

• Proteomic definitions of mesenchymal stem cells.

  Stem cells international 20110101

• Endophyte microbiome diversity in micropropagated Atriplex canescens and Atriplex torreyi var griffithsii.

  PloS one 20110101

• Interpreting linear support vector machine models with heat map molecule coloring.

  Journal of cheminformatics 20110101

• The self-organizing fractal theory as a universal discovery method: the phenomenon of life.

  Theoretical biology & medical modelling 20110101

• Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma.

  PloS one 20110101

• Patient considerations in the management of multiple sclerosis: development and clinical utility of oral agents.

  Patient preference and adherence 20110101

• A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project.

  BMC public health 20110101

• Shotgun sequencing of Yersinia enterocolitica strain W22703 (biotype 2, serotype O:9): genomic evidence for oscillation between invertebrates and mammals.

  BMC genomics 20110101

• Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications.

  Journal of hematology & oncology 20110101

• An illustrative case of subcutaneous panniculitis-like T-cell lymphoma.

  Journal of skin cancer 20110101

• Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish.

  PloS one 20110101

• Ticagrelor: the evidence for its clinical potential as an oral antiplatelet treatment for the reduction of major adverse cardiac events in patients with acute coronary syndromes.

  Core evidence 20110101

• Levels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients.

  Cancer cell international 20110101

• Extranodal rosai-dorfman disease with cutaneous and periodontal involvement: a rare presentation.

  Case reports in oncology 20110101

• Effect of a fat spread enriched with medium-chain triacylglycerols and a special fatty acid-micronutrient combination on cardiometabolic risk factors in overweight patients with diabetes.

  Nutrition & metabolism 20110101

• Relevance of laboratory testing for the diagnosis of primary immunodeficiencies: a review of case-based examples of selected immunodeficiencies.

  Clinical and molecular allergy : CMA 20110101

• Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

  PloS one 20110101

• The cyclophilin-binding agent Sanglifehrin A is a dendritic cell chemokine and migration inhibitor.

  PloS one 20110101

• Comprehensive analysis of transcript start sites in ly49 genes reveals an unexpected relationship with gene function and a lack of upstream promoters.

  PloS one 20110101

• Further improvements of the P. falciparum humanized mouse model.

  PloS one 20110101

• FORS-D Analysis in P. falciparum can Differentiate Classes of Genes Under Selection.

  Evolutionary bioinformatics online 20110101

• The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia.

  Clinical Medicine Insights. Oncology 20110101

• Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma.

  Genome biology 20110101

• Nucleosome DNA sequence structure of isochores.

  BMC genomics 20110101

• Comparative analysis of expressed sequence tags (ESTs) between drought-tolerant and -susceptible genotypes of chickpea under terminal drought stress.

  BMC plant biology 20110101

• Effect of vitamin E (Tri E®) on antioxidant enzymes and DNA damage in rats following eight weeks exercise.

  Nutrition journal 20110101

• Advanced paternal age is a risk factor for schizophrenia in Iranians.

  Annals of general psychiatry 20110101

• [Disorders of uric acid metabolism in rats with fructose-induced experimental insulin resistance syndrome].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101

• 2-Phenyl-7-(4-pyridyl-methyl-amino)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5(4H)-one.

  Acta crystallographica. Section E, Structure reports online 20110101

• Network modeling of the transcriptional effects of copy number aberrations in glioblastoma.

  Molecular systems biology 20110101

• Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding.

  PloS one 20110101

• Host specific diversity in Lactobacillus johnsonii as evidenced by a major chromosomal inversion and phage resistance mechanisms.

  PloS one 20110101

• Systems-scale analysis reveals pathways involved in cellular response to methamphetamine.

  PloS one 20110101

• Evolution of an endofungal lifestyle: Deductions from the Burkholderia rhizoxinica genome.

  BMC genomics 20110101

• Methotrexate toxicity in growing long bones of young rats: a model for studying cancer chemotherapy-induced bone growth defects in children.

  Journal of biomedicine & biotechnology 20110101

• Homologous recombination is stimulated by a decrease in dUTPase in Arabidopsis.

  PloS one 20110101

• Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis.

  BMC gastroenterology 20110101

• A complicated case of tacrolimus-induced rapid remission after cesarean section in the early third trimester for refractory severe ulcerative colitis flaring in the initial period of gestation.

  Case reports in gastroenterology 20110101

• The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease.

  PloS one 20110101

• Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling.

  PloS one 20110101

• More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus.

  Archaea (Vancouver, B.C.) 20110101

• UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.

  PloS one 20110101

• Localization of human RNase Z isoforms: dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation.

  PloS one 20110101

• Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features.

  PloS one 20110101

• Regulation of airway nucleotides in chronic lung diseases.

  Sub-cellular biochemistry 20110101

• [Diffuse large cell lymphoma and colon adenocarcinoma in patient with Waldenström's macroglobulinaemia].

  Srpski arhiv za celokupno lekarstvo 20110101

• Stimulation of growth of the human gastric pathogen Helicobacter pylori by atmospheric level of oxygen under high carbon dioxide tension.

  BMC microbiology 20110101

• Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae.

  BMC evolutionary biology 20110101

• Reduction in oxidatively generated DNA damage following smoking cessation.

  Tobacco induced diseases 20110101

• Using next generation transcriptome sequencing to predict an ectomycorrhizal metabolome.

  BMC systems biology 20110101

• Comparative proteomics analysis of proteins expressed in the I-1 and I-2 internodes of strawberry stolons.

  Proteome science 20110101

• A case series of allopurinol-induced toxic epidermal necrolysis.

  Indian journal of dermatology 20110101

• Complete genome sequence of Mycoplasma suis and insights into its biology and adaption to an erythrocyte niche.

  PloS one 20110101

• Fur activates the expression of Salmonella enterica pathogenicity island 1 by directly interacting with the hilD operator in vivo and in vitro.

  PloS one 20110101

• Treating ocular surface disease: new agents in development.

  Clinical ophthalmology (Auckland, N.Z.) 20110101

• Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

  PloS one 20110101

• Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition.

  BMC systems biology 20110101

• The importance of mitochondrial DNA in aging and cancer.

  Journal of aging research 20110101

• [Deficiency of adenosine desaminase (ADA): clinical, biochemical, molecular and treatment aspects].

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20110101

• Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics.

  BMC biochemistry 20110101

• Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effects on biomarkers of oxidation damage and antioxidant protection.

  Nutrition journal 20110101

• Pharmacology of purine and pyrimidine receptors. Preface.

  Advances in pharmacology (San Diego, Calif.) 20110101

• Regulation of leukocyte function by adenosine receptors.

  Advances in pharmacology (San Diego, Calif.) 20110101

• Allosteric modulation of purine and pyrimidine receptors.

  Advances in pharmacology (San Diego, Calif.) 20110101

• Molecular mechanisms of purine and pyrimidine nucleotide release.

  Advances in pharmacology (San Diego, Calif.) 20110101

• P2Y receptors in health and disease.

  Advances in pharmacology (San Diego, Calif.) 20110101

• A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication.

  PloS one 20110101

• Systematic and evolutionary insights derived from mtDNA COI barcode diversity in the Decapoda (Crustacea: Malacostraca).

  PloS one 20110101

• Nrt1 and Tna1-independent export of NAD+ precursor vitamins promotes NAD+ homeostasis and allows engineering of vitamin production.

  PloS one 20110101

• Host range, host specificity and hypothesized host shift events among viruses of lower vertebrates.

  Veterinary research 20110101

• Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana.

  BMC plant biology 20110101

• Spontaneous remission of Crohn's disease following a febrile infection: case report and literature review.

  BMC gastroenterology 20110101

• Modeling microRNA-mRNA interactions using PLS regression in human colon cancer.

  BMC medical genomics 20110101

• The enigmatic mitochondrial genome of Rhabdopleura compacta (Pterobranchia) reveals insights into selection of an efficient tRNA system and supports monophyly of Ambulacraria.

  BMC evolutionary biology 20110101

• LeishVet guidelines for the practical management of canine leishmaniosis.

  Parasites & vectors 20110101

• Possible roles of ectophosphatases in host-parasite interactions.

  Journal of parasitology research 20110101

• Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans?

  Journal of parasitology research 20110101

• Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms.

  BMC molecular biology 20110101

• Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer.

  BMC bioinformatics 20110101

• The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo.

  PloS one 20110101

• The proteomic complexity and rise of the primordial ancestor of diversified life.

  BMC evolutionary biology 20110101

• A high resolution map of a cyanobacterial transcriptome.

  Genome biology 20110101

• Construction of uricase-overproducing strains of Hansenula polymorpha and its application as biological recognition element in microbial urate biosensor.

  BMC biotechnology 20110101

• Adhesive polypeptides of Staphylococcus aureus identified using a novel secretion library technique in Escherichia coli.

  BMC microbiology 20110101

• Macromolecular bases of antischistosomal therapy.

  Current topics in medicinal chemistry 20110101

• Purine and pyrimidine pathways as targets in Plasmodium falciparum.

  Current topics in medicinal chemistry 20110101

• 6-oxopurine phosphoribosyltransferase: a target for the development of antimalarial drugs.

  Current topics in medicinal chemistry 20110101

• Path finding methods accounting for stoichiometry in metabolic networks.

  Genome biology 20110101

• What are fungal infections?

  Mediterranean journal of hematology and infectious diseases 20110101

• Development of oral immunomodulatory agents in the management of multiple sclerosis.

  Drug design, development and therapy 20110101

• Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer.

  PloS one 20110101

• Systematic exploitation of multiple receptor conformations for virtual ligand screening.

  PloS one 20110101

• Comparative transcriptome analysis of Bacillus subtilis responding to dissolved oxygen in adenosine fermentation.

  PloS one 20110101

• Novel ocular antihypertensive compounds in clinical trials.

  Clinical ophthalmology (Auckland, N.Z.) 20110101

• Adenosine A(2A) Receptor and IL-10 in Peripheral Blood Mononuclear Cells of Patients with Mild Cognitive Impairment.

  International journal of Alzheimer's disease 20110101

• Tophaceous gout and renal insufficiency: a new solution for an old therapeutic dilemma.

  Case reports in medicine 20110101

• Neutralising antibodies against ricin toxin.

  PloS one 20110101

• Assessment of the genetic risks of a metallic alloy used in medical implants.

  Genetics and molecular biology 20110101

• The hexameric structures of human heat shock protein 90.

  PloS one 20110101

• Adenosine in the inflamed gut: a Janus faced compound.

  Current medicinal chemistry 20110101

• The metabolic advantage of tumor cells.

  Molecular cancer 20110101

• Identification of maturation and protein synthesis related proteins from porcine oocytes during in vitro maturation.

  Proteome science 20110101

• Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.

  Nutrition & metabolism 20110101

• A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1.

  PloS one 20110101

• Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences.

  International journal of chronic obstructive pulmonary disease 20110101

• A large scale comparative genomic analysis reveals insertion sites for newly acquired genomic islands in bacterial genomes.

  BMC microbiology 20110101

• Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma.

  BMC cancer 20110101

• Comparative analysis of macrophage associated vectors for use in genetic vaccine.

  Genetic vaccines and therapy 20110101

• Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis.

  Critical care (London, England) 20110101

• Dissimilar roles of the four conserved acidic residues in the thermal stability of poly(A)-specific ribonuclease.

  International journal of molecular sciences 20110101

• Therapeutic effects of hydrogen in animal models of Parkinson's disease.

  Parkinson's disease 20110101

• Two-stage flux balance analysis of metabolic networks for drug target identification.

  BMC systems biology 20110101

• Genome-wide analysis of the transcription factor binding preference of human bi-directional promoters and functional annotation of related gene pairs.

  BMC systems biology 20110101

• Evolutionary history of Otophysi (Teleostei), a major clade of the modern freshwater fishes: Pangaean origin and Mesozoic radiation.

  BMC evolutionary biology 20110101

• Diploid-specific [corrected] genome stability genes of S. cerevisiae: genomic screen reveals haploidization as an escape from persisting DNA rearrangement stress.

  PloS one 20110101

• Bendamustine: safety and efficacy in the management of indolent non-hodgkins lymphoma.

  Clinical Medicine Insights. Oncology 20110101

• Iwr1 protein is important for preinitiation complex formation by all three nuclear RNA polymerases in Saccharomyces cerevisiae.

  PloS one 20110101

• Extracellular purine and pyrimidine catabolism in cell culture.

  Biotechnology progress 20110101

• Review and application of group theory to molecular systems biology.

  Theoretical biology & medical modelling 20110101

• Proteomic patterns of cervical cancer cell lines, a network perspective.

  BMC systems biology 20110101

• The evolution of enzyme specificity in the metabolic replicator model of prebiotic evolution.

  PloS one 20110101

• Collective dynamics of gene expression in cell populations.

  PloS one 20110101

• Global transcriptome response in Lactobacillus sakei during growth on ribose.

  BMC microbiology 20110101

• Comparative expression profiling of E. coli and S. aureus inoculated primary mammary gland cells sampled from cows with different genetic predispositions for somatic cell score.

  Genetics, selection, evolution : GSE 20110101

• In vivo versus in vitro protein abundance analysis of Shigella dysenteriae type 1 reveals changes in the expression of proteins involved in virulence, stress and energy metabolism.

  BMC microbiology 20110101

• Exploring internal features of 16S rRNA gene for identification of clinically relevant species of the genus Streptococcus.

  Annals of clinical microbiology and antimicrobials 20110101

• Zinc finger protein ZBTB20 expression is increased in hepatocellular carcinoma and associated with poor prognosis.

  BMC cancer 20110101

• Regulation of gene expression in ovarian cancer cells by luteinizing hormone receptor expression and activation.

  BMC cancer 20110101

• Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids.

  Nanoscale research letters 20110101

• Epidemiology of therapy-related myeloid neoplasms after treatment for pediatric acute lymphoblastic leukemia in the nordic countries.

  Mediterranean journal of hematology and infectious diseases 20110101

• Energetics and genetics across the prokaryote-eukaryote divide.

  Biology direct 20110101

• The effects of oral Ginkgo biloba supplementation on radiation-induced oxidative injury in the lens of rat.

  Pharmacognosy magazine 20110101

• Use of specific chemical reagents for detection of modified nucleotides in RNA.

  Journal of nucleic acids 20110101

• P2Y receptors as regulators of lung endothelial barrier integrity.

  Journal of cardiovascular disease research 20110101

• Genome-wide expression quantitative trait loci (eQTL) analysis in maize.

  BMC genomics 20110101

• Metabolic myopathy presenting with polyarteritis nodosa: a case report.

  Journal of medical case reports 20110101

• [Efficacy and safety of combination therapy with mizoribine and methotrexate for rheumatoid arthritis resistant with methotrexate].

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20110101

• Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker.

  PloS one 20110101

• An efficient approach to finding Siraitia grosvenorii triterpene biosynthetic genes by RNA-seq and digital gene expression analysis.

  BMC genomics 20110101

• Simultaneous clinical resolution of focal segmental glomerulosclerosis associated with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab.

  BMC nephrology 20110101

• Potential activity of the purine compounds caffeine and aminophylline on bacteria.

  Journal of global infectious diseases 20110101

• Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms.

  International journal of molecular sciences 20110101

• The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.

  PloS one 20110101

• 4D Flexible Atom-Pairs: An efficient probabilistic conformational space comparison for ligand-based virtual screening.

  Journal of cheminformatics 20110101

• GABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors.

  Frontiers in cellular neuroscience 20110101

• B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).

  PloS one 20110101

• Comparative genomics and transcriptomics of Propionibacterium acnes.

  PloS one 20110101

• Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.

  PloS one 20110101

• Enzymes are enriched in bacterial essential genes.

  PloS one 20110101

• Molecular characterization of the uncultivatable hemotropic bacterium Mycoplasma haemofelis.

  Veterinary research 20110101

• The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases.

  BMC biochemistry 20110101

• Genome-wide mutagenesis of Xanthomonas axonopodis pv. citri reveals novel genetic determinants and regulation mechanisms of biofilm formation.

  PloS one 20110101

• Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

  Clinical and experimental gastroenterology 20110101

• E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.

  PloS one 20110101

• Inorganic phosphate as an important regulator of phosphatases.

  Enzyme research 20110101

• Molecular Cloning and Characterization of P4 Nuclease from Leishmania infantum.

  Enzyme research 20110101

• Transplantable subcutaneous hepatoma 22a affects functional activity of resident tissue macrophages in periphery.

  International journal of cell biology 20110101

• Should metabolic diseases be systematically screened in nonsyndromic autism spectrum disorders?

  PloS one 20110101

• Comparative Proteomic Analysis of saccharopolyspora spinosa SP06081 and PR2 strains reveals the differentially expressed proteins correlated with the increase of spinosad yield.

  Proteome science 20110101

• Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways.

  PloS one 20110101

• Sirtuins, bioageing, and cancer.

  Journal of aging research 20110101

• Absolute quantification of microbial proteomes at different states by directed mass spectrometry.

  Molecular systems biology 20110101

• Conformational-dependent and independent RNA binding to the fragile x mental retardation protein.

  Journal of nucleic acids 20110101

• Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA.

  Journal of nucleic acids 20110101

• Advances in fine needle aspiration cytology for the diagnosis of pulmonary carcinoma.

  Pathology research international 20110101

• Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics.

  PloS one 20110101

• Generation, analysis and functional annotation of expressed sequence tags from the ectoparasitic mite Psoroptes ovis.

  Parasites & vectors 20110101

• 8-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells.

  Journal of radiation research 20110101

• Acupuncture May Stimulate Anticancer Immunity via Activation of Natural Killer Cells.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Acid phosphatases of budding yeast as a model of choice for transcription regulation research.

  Enzyme research 20110101

• A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model.

  PloS one 20110101

• Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors.

  PloS one 20110101

• An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors.

  PloS one 20110101

• Clinical relevance and treatment of nonautoimmune anemia in chronic lymphocytic leukemia.

  Cancer management and research 20110101

• The impact of fructose on renal function and blood pressure.

  International journal of nephrology 20110101

• New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.

  PloS one 20110101

• Sequence-dependent fluorescence of cyanine dyes on microarrays.

  PloS one 20110101

• Exploiting publicly available biological and biochemical information for the discovery of novel short linear motifs.

  PloS one 20110101

• Zinc-regulated DNA binding of the yeast Zap1 zinc-responsive activator.

  PloS one 20110101

• SEAS: a system for SEED-based pathway enrichment analysis.

  PloS one 20110101

• A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A.

  PloS one 20110101

• Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling.

  BMC systems biology 20110101

• Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats.

  Nutrition & metabolism 20110101

• Large-scale RNAi screen of G protein-coupled receptors involved in larval growth, molting and metamorphosis in the red flour beetle.

  BMC genomics 20110101

• Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus.

  BMC genomics 20110101

• Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism.

  Molecular systems biology 20110101

• Identification of new IS711 insertion sites in Brucella abortus field isolates.

  BMC microbiology 20110101

• Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes.

  Cardiovascular diabetology 20110101

• Polyphosphate--an ancient energy source and active metabolic regulator.

  Microbial cell factories 20110101

• Efficient overproduction of membrane proteins in Lactococcus lactis requires the cell envelope stress sensor/regulator couple CesSR.

  PloS one 20110101

• PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse.

  PloS one 20110101

• Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.

  PloS one 20110101

• Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.

  Marine drugs 20110101

• Use of nucleic Acid analogs for the study of nucleic Acid interactions.

  Journal of nucleic acids 20110101

• Structural diversity of biologically interesting datasets: a scaffold analysis approach.

  Journal of cheminformatics 20110101

• Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma.

  PloS one 20110101

• Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis.

  PloS one 20110101

• Culture enriched molecular profiling of the cystic fibrosis airway microbiome.

  PloS one 20110101

• Proteomic analysis reveals that iron availability alters the metabolic status of the pathogenic fungus Paracoccidioides brasiliensis.

  PloS one 20110101

• Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.

  PloS one 20110101

• Differential inhibitor sensitivity between human kinases VRK1 and VRK2.

  PloS one 20110101

• Lipopolysaccharide-Deficient Brucella Variants Arise Spontaneously during Infection.

  Frontiers in microbiology 20110101

• Integrating systems biology models and biomedical ontologies.

  BMC systems biology 20110101

• Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level.

  BMC genomics 20110101

• [The activity of antioxidant enzymes of erythrocytes under intensive physical activity on the background of D-ribose use].

  Voprosy pitaniia 20110101

• Selection of hepatitis C virus resistant to ribavirin.

  Virology journal 20110101

• Current and emerging treatments for the management of myasthenia gravis.

  Therapeutics and clinical risk management 20110101

• Variations of antioxidant properties and NO scavenging abilities during fermentation of tea.

  International journal of molecular sciences 20110101

• Clinical pharmacology of chemotherapy agents in older people with cancer.

  Current gerontology and geriatrics research 20110101

• Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

  Molecular systems biology 20110101

• The relationship between serum uric acid and spirometric values in participants in a health check: the Takahata study.

  International journal of medical sciences 20110101

• Gas6 downregulation impaired cytoplasmic maturation and pronuclear formation independent to the MPF activity.

  PloS one 20110101

• DARS-RNP and QUASI-RNP: new statistical potentials for protein-RNA docking.

  BMC bioinformatics 20110101

• The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1.

  PloS one 20110101

• Involvement of cytokines in slow wave sleep.

  Progress in brain research 20110101

• A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly.

  PloS one 20110101

• Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.

  PloS one 20110101

• Importance of suitable reference gene selection for quantitative real-time PCR: special reference to mouse myocardial infarction studies.

  PloS one 20110101

• Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica.

  BMC genomics 20110101

• Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs.

  BMC systems biology 20110101

• Cross-Genome Comparisons of Newly Identified Domains in Mycoplasma gallisepticum and Domain Architectures with Other Mycoplasma species.

  Comparative and functional genomics 20110101

• Purification and characterization of cytoplasmic NADP+-isocitrate dehydrogenase, and amplification of the NADP+-IDH gene from the wing-dimorphic sand field cricket, Gryllus firmus.

  Journal of insect science (Online) 20110101

• Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancer.

  BMC cancer 20110101

• P53 suppresses expression of the 14-3-3 gamma oncogene.

  BMC cancer 20110101

• Therapy-Related Myeloid Neoplasms in Chronic Lymphocytic Leukemia and Waldenstrom's Macroglobulinemia.

  Mediterranean journal of hematology and infectious diseases 20110101

• Comparison of the 'Ca. Liberibacter asiaticus' genome adapted for an intracellular lifestyle with other members of the Rhizobiales.

  PloS one 20110101

• Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells.

  BMC systems biology 20110101

• Bacterial Catabolism of Dimethylsulfoniopropionate (DMSP).

  Frontiers in microbiology 20110101

• Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.

  PloS one 20110101

• Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-Tumor Agents.

  Scientia pharmaceutica 20110101

• Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs.

  PloS one 20110101

• Cellular kinases incorporated into HIV-1 particles: passive or active passengers?

  Retrovirology 20110101

• Biochemical measurement of neonatal hypoxia.

  Journal of visualized experiments : JoVE 20110101

• Identification of ionotrophic purinergic receptors in Huh-7 cells and their response towards structural proteins of HCV genotype 3a.

  Virology journal 20110101

• Promising pharmacological, molecular and cellular treatments of autoimmune hepatitis.

  Current pharmaceutical design 20110101

• Fragmentation of contaminant and endogenous DNA in ancient samples determined by shotgun sequencing; prospects for human palaeogenomics.

  PloS one 20110101

• Structural mechanism of S-adenosyl methionine binding to catechol O-methyltransferase.

  PloS one 20110101

• Cell-specific aptamers as emerging therapeutics.

  Journal of nucleic acids 20110101

• Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia.

  Clinical proteomics 20110101

• Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome.

  PloS one 20110101

• Oxidative DNA Damage in Blood of CVD Patients Taking Detralex.

  The open cardiovascular medicine journal 20110101

• [Inborn errors of purine and pyrimidyne metabolism].

  Postepy biochemii 20110101

• Clostridium difficile Infection and Inflammatory Bowel Disease: A Review.

  Gastroenterology research and practice 20110101

• Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.

  PloS one 20110101

• Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase.

  PloS one 20110101

• Phosphorylation provides a negative mode of regulation for the yeast Rab GTPase Sec4p.

  PloS one 20110101

• Determinants, discriminants, conserved residues--a heuristic approach to detection of functional divergence in protein families.

  PloS one 20110101

• Metagenome plasticity of the bovine abomasal microbiota in immune animals in response to Ostertagia ostertagi infection.

  PloS one 20110101

• Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment.

  Proteome science 20110101

• Protection from experimental cerebral malaria with a single dose of radiation-attenuated, blood-stage Plasmodium berghei parasites.

  PloS one 20110101

• Gene expression changes in phosphorus deficient potato (Solanum tuberosum L.) leaves and the potential for diagnostic gene expression markers.

  PloS one 20110101

• Functional characterization of the dendritically localized mRNA neuronatin in hippocampal neurons.

  PloS one 20110101

• The genetic basis of salinity tolerance traits in Arctic charr (Salvelinus alpinus).

  BMC genetics 20110101

• Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence.

  Veterinary research 20110101

• Lipopolysaccharide inhibits the channel activity of the P2X7 receptor.

  Mediators of inflammation 20110101

• Establishing a markerless genetic exchange system for Methanosarcina mazei strain Gö1 for constructing chromosomal mutants of small RNA genes.

  Archaea (Vancouver, B.C.) 20110101

• Synthetic RNA silencing in bacteria - antimicrobial discovery and resistance breaking.

  Frontiers in microbiology 20110101

• Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles.

  Microbial cell factories 20110101

• Serum uri acid: neuroprotection in thrombolysis. The Bergen NORSTROKE study.

  BMC neurology 20110101

• A comparative study on gene-set analysis methods for assessing differential expression associated with the survival phenotype.

  BMC bioinformatics 20110101

• How yeast re-programmes its transcriptional profile in response to different nutrient impulses.

  BMC systems biology 20110101

• Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke.

  PloS one 20110101

• Targeting pannexin1 improves seizure outcome.

  PloS one 20110101

• Characterization of the biosynthesis, processing and kinetic mechanism of action of the enzyme deficient in mucopolysaccharidosis IIIC.

  PloS one 20110101

• Mizoribine provides effective treatment of sequential histological change of arteritis and reduction of inflammatory cytokines and chemokines in an animal model of Kawasaki disease.

  Pediatric rheumatology online journal 20110101

• Complexity of bidirectional transcription and alternative splicing at human RCAN3 locus.

  PloS one 20110101

• Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis.

  Clinical ophthalmology (Auckland, N.Z.) 20110101

• D-ribose induces cellular protein glycation and impairs mouse spatial cognition.

  PloS one 20110101

• Exploring DNA topoisomerase I ligand space in search of novel anticancer agents.

  PloS one 20110101

• The eukaryotic-type serine/threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis.

  PloS one 20110101

• Clinical and genetic analyses of three Korean families with hereditary hemorrhagic telangiectasia.

  BMC medical genetics 20110101

• Differential chromatin proteomics of the MMS-induced DNA damage response in yeast.

  Proteome science 20110101

• Enrollment characteristics and risk behaviors of injection drug users participating in the Bangkok Tenofovir Study, Thailand.

  PloS one 20110101

• Deoxyribozymes: new therapeutics to treat central nervous system disorders.

  Frontiers in molecular neuroscience 20110101

• Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases.

  Journal of nucleic acids 20110101

• Adaptation of organisms by resonance of RNA transcription with the cellular redox cycle.

  PloS one 20110101

• Development of vaccines against burkholderia pseudomallei.

  Frontiers in microbiology 20110101

• Immunomodulators and immunosuppressants for Japanese patients with ulcerative colitis.

  ISRN gastroenterology 20110101

• Role of mucosal inflammation in eosinophilic esophagitis: review of the literature.

  ISRN gastroenterology 20110101

• Regulation of the yeast metabolic cycle by transcription factors with periodic activities.

  BMC systems biology 20110101

• The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans.

  Frontiers in microbiology 20110101

• Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9.

  Microbial cell factories 20110101

• Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts.

  Microbial cell factories 20110101

• Some aspects of purinergic signaling in the ventricular system of porcine brain.

  Acta veterinaria Scandinavica 20110101

• Internal control genes for quantitative RT-PCR expression analysis in mouse osteoblasts, osteoclasts and macrophages.

  BMC research notes 20110101

• Dithizone staining of intracellular zinc: an unexpected and versatile counterscreen for auxotrophic marker genes in Saccharomyces cerevisiae.

  PloS one 20110101

• A system for performing high throughput assays of synaptic function.

  PloS one 20110101

• Perfluoroalkyl chemicals and elevated serum uric acid in US adults.

  Clinical epidemiology 20110101

• Adenosine receptors and fibrosis: a translational review.

  F1000 biology reports 20110101

• Antivirals reduce the formation of key Alzheimer's disease molecules in cell cultures acutely infected with herpes simplex virus type 1.

  PloS one 20110101

• Molecular organization and phylogenetic analysis of 5S rDNA in crustaceans of the genus Pollicipes reveal birth-and-death evolution and strong purifying selection.

  BMC evolutionary biology 20110101

• Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control.

  Genome biology 20110101

• Strategies for Intracellular Survival of Burkholderia pseudomallei.

  Frontiers in microbiology 20110101

• tRNA Modification and Genetic Code Variations in Animal Mitochondria.

  Journal of nucleic acids 20110101

• Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse.

  Biotechnology for biofuels 20110101

• Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose.

  Proteome science 20110101

• Hydration sites of unpaired RNA bases: a statistical analysis of the PDB structures.

  BMC structural biology 20110101

• Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA.

  Journal of nucleic acids 20110101

• The transcriptome of the novel dinoflagellate Oxyrrhis marina (Alveolata: Dinophyceae): response to salinity examined by 454 sequencing.

  BMC genomics 20110101

• pcrEfficiency: a Web tool for PCR amplification efficiency prediction.

  BMC bioinformatics 20110101

• Academic aspects of lunar water resources and their relevance to lunar protolife.

  International journal of molecular sciences 20110101

• Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.

  PloS one 20110101

• Integrated proteomic and metabolomic analysis of an artificial microbial community for two-step production of vitamin C.

  PloS one 20110101

• The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets.

  BMC microbiology 20110101

• Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats.

  Indian journal of pharmacology 20110101

• Preventive fluid and dietary therapy for urolithiasis: An appraisal of strength, controversies and lacunae of current literature.

  Indian journal of urology : IJU : journal of the Urological Society of India 20110101

• Comparison of azathioprine with mycophenolate mofetil in a living donor kidney transplant programme.

  Indian journal of nephrology 20110101

• Transcriptome analysis of adaptive heat shock response of Streptococcus thermophilus.

  PloS one 20110101

• Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

  PloS one 20110101

• Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury.

  PloS one 20110101

• Folate metabolic pathways in Leishmania.

  Essays in biochemistry 20110101

• Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast.

  BMC biology 20110101

• PMS5: an efficient exact algorithm for the (ℓ, d)-motif finding problem.

  BMC bioinformatics 20110101

• Energy drinks and the neurophysiological impact of caffeine.

  Frontiers in neuroscience 20110101

• Cyclin-Dependent Kinase 5/p35/p39: A Novel and Imminent Therapeutic Target for Diabetes Mellitus.

  International journal of endocrinology 20110101

• Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model.

  PloS one 20110101

• Oncolytic adenoviruses armed with thymidine kinase can be traced by PET imaging and show potent antitumoural effects by ganciclovir dosing.

  PloS one 20110101

• In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement.

  Proteome science 20110101

• Recent progress in the study of brown adipose tissue.

  Cell & bioscience 20110101

• A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice.

  PloS one 20110101

• Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts.

  BMC pharmacology 20110101

• The evolution of metabolic networks of E. coli.

  BMC systems biology 20110101

• In vivo and in silico determination of essential genes of Campylobacter jejuni.

  BMC genomics 20110101

• Hepatitis B virus impairs TLR9 expression and function in plasmacytoid dendritic cells.

  PloS one 20110101

• An alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference.

  PloS one 20110101

• Transcriptional and functional analysis of the effects of magnolol: inhibition of autolysis and biofilms in Staphylococcus aureus.

  PloS one 20110101

• Composite effects of gene determinants on the translation speed and density of ribosomes.

  Genome biology 20110101

• Reversine increases multipotent human mesenchymal cells differentiation potential.

  Journal of biological regulators and homeostatic agents 20110101

• Impact of manganese, copper and zinc ions on the transcriptome of the nosocomial pathogen Enterococcus faecalis V583.

  PloS one 20110101

• Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation.

  BMC genomics 20110101

• GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS.

  Frontiers in molecular neuroscience 20110101

• Gout, genetics and ABC transporters.

  F1000 biology reports 20110101

• Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites.

  International journal of molecular sciences 20110101

• Kinase inhibitors from marine sponges.

  Marine drugs 20110101

• The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats.

  PloS one 20110101

• Phylogenetic diversity, host-specificity and community profiling of sponge-associated bacteria in the northern Gulf of Mexico.

  PloS one 20110101

• Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

  PloS one 20110101

• Proteome analysis of bronchoalveolar lavage in pulmonary langerhans cell histiocytosis.

  Journal of clinical bioinformatics 20110101

• The synthesis of C8-aryl purines, nucleosides and phosphoramidites.

  Critical reviews in eukaryotic gene expression 20110101

• Mechanisms of B cell autoimmunity in SLE.

  Arthritis research & therapy 20110101

• A Systematic Review and Meta-Analysis of Front-line Anthracycline-Based Chemotherapy Regimens for Peripheral T-Cell Lymphoma.

  ISRN hematology 20110101

• Time-resolved transcriptomics and bioinformatic analyses reveal intrinsic stress responses during batch culture of Bacillus subtilis.

  PloS one 20110101

• Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma.

  PloS one 20110101

• A plant virus movement protein regulates the Gcn2p kinase in budding yeast.

  PloS one 20110101

• 8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription.

  PloS one 20110101

• The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells.

  PloS one 20110101

• Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.

  Molecular biology international 20110101

• Use of antimony in the treatment of leishmaniasis: current status and future directions.

  Molecular biology international 20110101

• Modulation of metabolism and switching to biofilm prevail over exopolysaccharide production in the response of Rhizobium alamii to cadmium.

  PloS one 20110101

• Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

  PloS one 20110101

• Serum metabolic profile in multiple sclerosis patients.

  Multiple sclerosis international 20110101

• Genomic alterations in rectal tumors and response to neoadjuvant chemoradiotherapy: an exploratory study.

  Radiation oncology (London, England) 20110101

• Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma.

  PloS one 20110101

• Selection of stable reference genes for quantitative rt-PCR comparisons of mouse embryonic and extra-embryonic stem cells.

  PloS one 20110101

• Th2-associated alternative Kupffer cell activation promotes liver fibrosis without inducing local inflammation.

  International journal of biological sciences 20110101

• Progesterone induces mucosal immunity in a rodent model of human taeniosis by Taenia solium.

  International journal of biological sciences 20110101

• The role of uridine adenosine tetraphosphate in the vascular system.

  Advances in pharmacological sciences 20110101

• Juvenile myasthenia gravis: a paediatric perspective.

  Autoimmune diseases 20110101

• Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional Chinese medicine.

  Genome biology 20110101

• Association between Serum Uric Acid Levels and Diabetes Mellitus.

  International journal of endocrinology 20110101

• The N-terminal domain and glycosomal localization of Leishmania initial acyltransferase LmDAT are important for lipophosphoglycan synthesis.

  PloS one 20110101

• Potential peripheral biomarkers for the diagnosis of Alzheimer's disease.

  International journal of Alzheimer's disease 20110101

• [Covalent chloramine inhibitors of blood platelet functions: computational indices for their reactivity and antiplatelet activity].

  Biofizika 20110101

• [Efficiency perindopril at patients with arterial hypertension and obesity].

  Kardiologiia 20110101

• The association of DNA damage response and nucleotide level modulation with the antibacterial mechanism of the anti-folate drug trimethoprim.

  BMC genomics 20110101

• Integration of gene expression data with prior knowledge for network analysis and validation.

  BMC research notes 20110101

• A showcase of bench-to-bedside regenerative medicine at the 2010 ASNTR.

  TheScientificWorldJournal 20110101

• Involvement of P2Y receptors in the protective effect of ATP towards the cell damage in HaCaT cells exposed to H₂O₂.

  The Journal of toxicological sciences 20110101

• Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice.

  PloS one 20110101

• hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene.

  PloS one 20110101

• Transcriptomic analyses during the transition from biomass production to lipid accumulation in the oleaginous yeast Yarrowia lipolytica.

  PloS one 20110101

• Microarray-based transcriptomic analysis of differences between long-term gregarious and solitarious desert locusts.

  PloS one 20110101

• Effect and safety of mycophenolate mofetil in idiopathic pulmonary fibrosis.

  Pulmonary medicine 20110101

• Gliotransmission modulates baseline mechanical nociception.

  Molecular pain 20110101

• Effect of caffeine on the intraocular pressure in patients with primary open angle glaucoma.

  Clinical ophthalmology (Auckland, N.Z.) 20110101

• Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells.

  PloS one 20110101

• A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis.

  PloS one 20110101

• Azathioprine induced cholestatic hepatitis.

  Indian journal of pharmacology 20110101

• Drosophila Dynein intermediate chain gene, Dic61B, is required for spermatogenesis.

  PloS one 20110101

• A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release.

  Arthritis research & therapy 20110101

• Accelerated large-scale multiple sequence alignment.

  BMC bioinformatics 20110101

• Efficacy of vinblastine in central nervous system Langerhans cell histiocytosis: a nationwide retrospective study.

  Orphanet journal of rare diseases 20110101

• Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR.

  BMC microbiology 20110101

• Modulation of phosphofructokinase (PFK) from Setaria cervi, a bovine filarial parasite, by different effectors and its interaction with some antifilarials.

  Parasites & vectors 20110101

• Allopurinol causing drug rash with eosinophilia and systemic symptoms syndrome: a challenging diagnosis.

  International journal of general medicine 20110101

• Evidence for widespread genomic methylation in the migratory locust, Locusta migratoria (Orthoptera: Acrididae).

  PloS one 20110101

• Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra.

  PloS one 20110101

• Mutation screening of multiple genes in Spanish patients with autosomal recessive retinitis pigmentosa by targeted resequencing.

  PloS one 20110101

• Identification of lactoferricin B intracellular targets using an Escherichia coli proteome chip.

  PloS one 20110101

• Molecular foundations of reproductive lethality in Arabidopsis thaliana.

  PloS one 20110101

• [A case of Xanthinuria in a patient with marked hypouricemia].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20110101

• Purine biosynthesis in archaea: variations on a theme.

  Biology direct 20110101

• Differential effects of acute (extenuating) and chronic (training) exercise on inflammation and oxidative stress status in an animal model of type 2 diabetes mellitus.

  Mediators of inflammation 20110101

• A HNMR-based metabonomics study of postmenopausal osteoporosis and intervention effects of Er-Xian Decoction in ovariectomized rats.

  International journal of molecular sciences 20110101

• Arsenic exposure and the induction of human cancers.

  Journal of toxicology 20110101

• Transcriptomics of a giant freshwater prawn (Macrobrachium rosenbergii): de novo assembly, annotation and marker discovery.

  PloS one 20110101

• The role of the transcription factor SIM2 in prostate cancer.

  PloS one 20110101

• Incorporation of 3-aminobenzanthrone into 2'-deoxyoligonucleotides and its impact on duplex stability.

  Journal of nucleic acids 20110101

• [Low-dose combination of perindopril arginine with indapamide in correction of metabolic syndrome].

  Terapevticheskii arkhiv 20110101

• Normalizing for individual cell population context in the analysis of high-content cellular screens.

  BMC bioinformatics 20110101

• Characterization of a proximal Sp1 response element in the mouse Dlk2 gene promoter.

  BMC molecular biology 20110101

• Detecting the symplesiomorphy trap: a multigene phylogenetic analysis of terebelliform annelids.

  BMC evolutionary biology 20110101

• Correlation of gene expression and protein production rate - a system wide study.

  BMC genomics 20110101

• The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.

  Stem cells international 20110101

• The immune response to tumors as a tool toward immunotherapy.

  Clinical & developmental immunology 20110101

• Strategies for reducing or preventing the generation of oxidative stress.

  Oxidative medicine and cellular longevity 20110101

• Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosis.

  BMC genomics 20110101

• Clinical and functional characterization of URAT1 variants.

  PloS one 20110101

• Pivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis.

  PloS one 20110101

• Employing machine learning for reliable miRNA target identification in plants.

  BMC genomics 20110101

• Depolarization-mediated regulation of alternative splicing.

  Frontiers in neuroscience 20110101

• The role of ATP in sleep regulation.

  Frontiers in neurology 20110101

• Interrogation of global mutagenesis data with a genome scale model of Neisseria meningitidis to assess gene fitness in vitro and in sera.

  Genome biology 20110101

• Partition decoupling for multi-gene analysis of gene expression profiling data.

  BMC bioinformatics 20110101

• Carbohydrate metabolism is essential for the colonization of Streptococcus thermophilus in the digestive tract of gnotobiotic rats.

  PloS one 20110101

• Thiopurine methyltransferase predicts the extent of cytotoxicty and DNA damage in astroglial cells after thioguanine exposure.

  PloS one 20110101

• Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity.

  PloS one 20110101

• Predicting biological functions of compounds based on chemical-chemical interactions.

  PloS one 20110101

• Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells.

  PloS one 20110101

• Triple combination antiviral drug (TCAD) composed of amantadine, oseltamivir, and ribavirin impedes the selection of drug-resistant influenza A virus.

  PloS one 20110101

• Nanomedicine as an emerging approach against intracellular pathogens.

  International journal of nanomedicine 20110101

• A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.

  PloS one 20110101

• Priming DNA replication from triple helix oligonucleotides: possible threestranded DNA in DNA polymerases.

  Molecular biology international 20110101

• Critical appraisal of ticagrelor in the management of acute coronary syndrome.

  Therapeutics and clinical risk management 20110101

• Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.

  Clinical epigenetics 20110101

• Effect of lactobacilli on paracellular permeability in the gut.

  Nutrients 20110101

• The effect of raw soybean on oxidative status of digestive organs in mice.

  International journal of molecular sciences 20110101

• Oxidative and antioxidative defense system in testicular torsion/detorsion.

  Indian journal of urology : IJU : journal of the Urological Society of India 20110101

• Efficacy of Intralesional Bleomycin in Palmo-plantar and Periungual Warts.

  Journal of cutaneous and aesthetic surgery 20110101

• Emerging role of rasburicase in the management of increased plasma uric acid levels in patients with hematologic malignancies.

  Journal of blood medicine 20110101

• Role of ofatumumab in treatment of chronic lymphocytic leukemia.

  Journal of blood medicine 20110101

• An update on the management of peripheral T-cell lymphoma and emerging treatment options.

  Journal of blood medicine 20110101

• Proton magnetic resonance spectroscopy in depression.

  Indian journal of psychiatry 20110101

• Mthfs is an Essential Gene in Mice and a Component of the Purinosome.

  Frontiers in genetics 20110101

• DNA methylation: a timeline of methods and applications.

  Frontiers in genetics 20110101

• [Mass spectrometry of triterpene glycosides molecular complexation with purine bases of nucleic acids].

  Bioorganicheskaia khimiia 20110101

• Acute pulmonary embolism decreases adenosine plasma levels in anesthetized pigs.

  ISRN cardiology 20110101

• Predicting the possibility of two newly isolated phenetheren ring containing compounds from Aristolochia manshuriensis as CDK2 inhibitors.

  Bioinformation 20110101

• Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype.

  Scientific reports 20110101

• Drug-target network in myocardial infarction reveals multiple side effects of unrelated drugs.

  Scientific reports 20110101

• A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA.

  Scientific reports 20110101

• Amino acids biosynthesis and nitrogen assimilation pathways: a great genomic deletion during eukaryotes evolution.

  BMC genomics 20110101

• Protease-associated cellular networks in malaria parasite Plasmodium falciparum.

  BMC genomics 20110101

• Improvement in the prediction of the translation initiation site through balancing methods, inclusion of acquired knowledge and addition of features to sequences of mRNA.

  BMC genomics 20110101

• In silico secretome analysis approach for next generation sequencing transcriptomic data.

  BMC genomics 20110101

• Prediction of dinucleotide-specific RNA-binding sites in proteins.

  BMC bioinformatics 20110101

• Serum malondialdehyde level: Surrogate stress marker in the Sikkimese diabetics.

  Journal of natural science, biology, and medicine 20110101

• Culture environment-induced pluripotency of SACK-expanded tissue stem cells.

  Journal of biomedicine & biotechnology 20110101

• Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency.

  Frontiers in immunology 20110101

• Role of heat shock protein 70 in innate alloimmunity.

  Frontiers in immunology 20110101

• Predicted Relative Metabolomic Turnover (PRMT): determining metabolic turnover from a coastal marine metagenomic dataset.

  Microbial informatics and experimentation 20110101

• The Plastid Outer Envelope - A Highly Dynamic Interface between Plastid and Cytoplasm.

  Frontiers in plant science 20110101

• [Some inhibitors of purine nucleoside phosphorylase].

  Biomeditsinskaia khimiia 20110101

• [Differentiated approaches to the treatment of chronic pancreatitis patients with metabolic syndrome].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101

• Quantitative proteomic analysis of wheat cultivars with differing drought stress tolerance.

  Frontiers in plant science 20110101

• The metabolite transporters of the plastid envelope: an update.

  Frontiers in plant science 20110101

• Defining the plant peroxisomal proteome: from Arabidopsis to rice.

  Frontiers in plant science 20110101

• Promoters with cancer cell-specific activity for melanoma gene therapy.

  Acta naturae 20110101

• Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications.

  Acta naturae 20110101

• Escort aptamers: new tools for the targeted delivery of therapeutics into cells.

  Acta naturae 20110101

• Test systems to study the structure and function of uncoupling protein 1: a critical overview.

  Frontiers in endocrinology 20110101

• A rapid, simple DNA mismatch repair substrate construction method.

  Frontiers in oncology 20110101

• Purine nucleoside phosphorylase deficiency with a novel PNP gene mutation: a first case report from India.

  BMJ case reports 20110101

• The role of Zn2+ on the structure and stability of murine adenosine deaminase.

  The journal of physical chemistry. B 20101216

• Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analogues.

  The journal of physical chemistry. B 20101216

• Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas.

  Cancer research 20101215

• Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis.

  Nature communications 20101214

• Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints.

  Experimental cell research 20101210

• 3-Methoxalylchromone--a novel versatile reagent for the regioselective purine isostere synthesis.

  Organic & biomolecular chemistry 20101207

• Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

  Nature 20101202

• Synthesis, characterization and in vitro anti-tumor activities of novel 9-ethyl-9H-purine derivatives.

  Investigational new drugs 20101201

• Extracellular purine metabolism in blood vessels (Part II): Activity of ecto-enzymes in blood vessels of patients with abdominal aortic aneurysm.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20101201

• The role of adenosine receptors in rheumatoid arthritis.

  Autoimmunity reviews 20101201

• Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects.

  European journal of applied physiology 20101201

• Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats.

  British journal of pharmacology 20101201

• Brain hypoxanthine concentration correlates to lactate/pyruvate ratio but not intracranial pressure in patients with acute liver failure.

  Journal of hepatology 20101201

• Considerations concerning design and mechanism of action of a new class of anticancer dual DNA intercalators.

  Medical hypotheses 20101201

• Purine molecules as hypnogenic factors role of adenosine, ATP, and caffeine.

  Central nervous system agents in medicinal chemistry 20101201

• Synthesis and cytostatic activity of purine nucleosides derivatives of allofuranose.

  European journal of medicinal chemistry 20101201

• Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.

  Protein science : a publication of the Protein Society 20101201

• In vitro effects of ethanol with aspirin on rat brain synaptosomes: the potential protective role of betaine.

  The International journal of neuroscience 20101201

• Exercise improves hemodynamic profiles and increases red blood cell concentrations of purine nucleotides in a rodent model.

  Therapeutic advances in cardiovascular disease 20101201

• C4GEM, a genome-scale metabolic model to study C4 plant metabolism.

  Plant physiology 20101201

• Natural variation in Arabidopsis leads to the identification of REME1, a pentatricopeptide repeat-DYW protein controlling the editing of mitochondrial transcripts.

  Plant physiology 20101201

• Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon.

  Analytical chemistry 20101201

• Acetazolamide-based fungal chitinase inhibitors.

  Bioorganic & medicinal chemistry 20101201

• Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models.

  Bioorganic & medicinal chemistry 20101201

• Selective 13C labeling of nucleotides for large RNA NMR spectroscopy using an E. coli strain disabled in the TCA cycle.

  Journal of biomolecular NMR 20101201

• Profiles of purine metabolism in leaves and roots of Camellia sinensis seedlings.

  Plant & cell physiology 20101201

• Hairy cell leukemia: current therapies and future directions.

  Expert review of hematology 20101201

• Adult T-cell leukemia-lymphoma: current treatment strategies and novel immunological approaches.

  Expert review of hematology 20101201

• Effect of quinoa seeds (Chenopodium quinoa) in diet on some biochemical parameters and essential elements in blood of high fructose-fed rats.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20101201

• Metabolism of [U-(13)C]aspartate by astroglial cultures: nuclear magnetic resonance analysis of the culture media.

  Neurochemical research 20101201

• Rectal non-Hodgkin's lymphoma in an infliximab treated patient with ulcerative colitis and primary sclerosing cholangitis.

  Journal of Crohn's & colitis 20101201

• [Hyperuricemia and metabolic syndrome].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20101201

• Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.

  PLoS computational biology 20101201

• High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.

  PLoS biology 20101201

• Inhibition of potassium currents as a pharmacologic target for investigation in chronic lymphocytic leukemia.

  Drug news & perspectives 20101201

• A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

  PLoS genetics 20101201

• The molecular targets for the diagnosis and treatment of pancreatic cancer.

  Gut and liver 20101201

• Rituximab monotherapy for splenic marginal zone lymphoma with villous lymphocytes: report on long-term disease control for two patients with recurrence after splenectomy.

  Sao Paulo medical journal = Revista paulista de medicina 20101201

• [Adenosine deaminase as costimulatory molecule and marker of cellular immunity].

  Investigacion clinica 20101201

• Dihydrofolate reductase gene variations in susceptibility to disease and treatment outcomes.

  Current genomics 20101201

• Cidofovir Activity against Poxvirus Infections.

  Viruses 20101201

• Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.

  Mutation research 20101128

• ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.

  Mutation research 20101128

• Oxidized purine nucleotides, genome instability and neurodegeneration.

  Mutation research 20101128

• Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.

  The Journal of biological chemistry 20101126

• Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses.

  Journal of medicinal chemistry 20101125

• Chemoselective multicomponent one-pot assembly of purine precursors in water.

  Journal of the American Chemical Society 20101124

• The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals.

  The Biochemical journal 20101115

• Solid-phase synthesis of highly diverse purine-hydroxyquinolinone bisheterocycles.

  Journal of combinatorial chemistry 20101108

• Cysteine-scanning analysis of helices TM8, TM9a, and TM9b and intervening loops in the YgfO xanthine permease: a carboxyl group is essential at ASP-276.

  The Journal of biological chemistry 20101105

• Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.

  Annals of hematology 20101101

• Calculations of binding affinity between C8-substituted GTP analogs and the bacterial cell-division protein FtsZ.

  European biophysics journal : EBJ 20101101

• Cell-free plasma DNA and purine nucleotide degradation markers following weightlifting exercise.

  European journal of applied physiology 20101101

• Uric acid and evolution.

  Rheumatology (Oxford, England) 20101101

• Reconstitution in liposome bilayers enhances nucleotide binding affinity and ATP-specificity of TrwB conjugative coupling protein.

  Biochimica et biophysica acta 20101101

• Dietary purines in vegetarian meat analogues.

  Journal of the science of food and agriculture 20101101

• Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments.

  Environmental microbiology 20101101

• Environment influences on the aromatic character of nucleobases and amino acids.

  Journal of molecular modeling 20101101

• Purine receptors modulate chondrocyte extracellular inorganic pyrophosphate production.

  Osteoarthritis and cartilage 20101101

• Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry.

  Molecular bioSystems 20101101

• Nearest-neighbor nitrogen and oxygen distances in the iron(II)-DNA complex studied by extended X-ray absorption fine structure.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101101

• MTHFR polymorphisms in relation to ovarian cancer risk.

  Gynecologic oncology 20101101

• Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase.

  European journal of medicinal chemistry 20101101

• ATP and the purine type 2 X7 receptor affect sleep.

  Journal of applied physiology (Bethesda, Md. : 1985) 20101101

• A convenient synthesis and molecular modeling study of novel purine and pyrimidine derivatives as CDK2/cyclin A3 inhibitors.

  Bioorganic & medicinal chemistry 20101101

• An aminotransferase branch point connects purine catabolism to amino acid recycling.

  Nature chemical biology 20101101

• Adenylosuccinate lyase deficiency in the United Kingdom pediatric population: first three cases.

  Pediatric neurology 20101101

• Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells.

  Journal of cell science 20101101

• Standard of care and novel treatments for chronic lymphocytic leukemia.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101101

• Homodimerization of pokeweed antiviral protein as a mechanism to limit depurination of pokeweed ribosomes.

  Molecular plant pathology 20101101

• Enzymatic synthesis of nucleosides by nucleoside phosphorylase co-expressed in Escherichia coli.

  Journal of Zhejiang University. Science. B 20101101

• Adaptive immunity against Leishmania nucleoside hydrolase maps its c-terminal domain as the target of the CD4+ T cell-driven protective response.

  PLoS neglected tropical diseases 20101101

• Local gene regulation details a recognition code within the LacI transcriptional factor family.

  PLoS computational biology 20101101

• Genome-wide association between branch point properties and alternative splicing.

  PLoS computational biology 20101101

• Semisynthesis of 6-chloropurine-2'-deoxyriboside 5'-dimethoxytrityl 3'-(2-cyanoethyl-N,N-diisopropylamino)phosphoramidite and its use in the synthesis of fluorescently labeled oligonucleotides.

  Nucleosides, nucleotides & nucleic acids 20101101

• Metabolomics to unveil and understand phenotypic diversity between pathogen populations.

  PLoS neglected tropical diseases 20101101

• Scaling properties and fractality in the distribution of coding segments in eukaryotic genomes revealed through a block entropy approach.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20101101

• Refractory chronic lymphocytic leukemia--new therapeutic strategies.

  Oncotarget 20101101

• Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia.

  Cell death & disease 20101101

• Buying time-the immune system determinants of the incubation period to respiratory viruses.

  Viruses 20101101

• Toxin-based therapeutic approaches.

  Toxins 20101101

• Beyond hairy cell: the activity of cladribine in other hematologic malignancies.

  Blood 20101021

• Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding.

  Journal of the American Chemical Society 20101020

• Photogeneration and reactivity of naphthoquinone methides as purine selective DNA alkylating agents.

  Journal of the American Chemical Society 20101020

• Variability in G-protein-coupled signaling studied with microfluidic devices.

  Biophysical journal 20101020

• Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei.

  Biochemistry 20101019

• The spermine-bisaryl conjugate as a potent inducer of B- to Z-DNA transition.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20101018

• Hairy cell leukemia: evaluation of the long-term outcome in 121 patients.

  Cancer 20101015

• Optimal packaging of FIV genomic RNA depends upon a conserved long-range interaction and a palindromic sequence within gag.

  Journal of molecular biology 20101015

• Electrochemical determination of guanine and adenine by CdS microspheres modified electrode and evaluation of damage to DNA purine bases by UV radiation.

  Biosensors & bioelectronics 20101015

• A class of novel conjugates of substituted purine and Gly-AA-OBzl: synthesis and evaluation of orally analgesic activity.

  Bioorganic & medicinal chemistry letters 20101015

• Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring.

  Bioorganic & medicinal chemistry 20101015

• One-pot etherification of purine nucleosides and pyrimidines.

  Organic letters 20101015

• In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi.

  Journal of medicinal chemistry 20101014

• Analysis of the HPRT1 gene in 35 Italian Lesch-Nyhan families: 45 patients and 77 potential female carriers.

  Mutation research 20101013

• A pharmacy practice laboratory exercise to apply biochemistry concepts.

  American journal of pharmaceutical education 20101011

• Expansion of human cord blood hematopoietic stem cells for transplantation.

  Cell stem cell 20101008

• Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial.

  Blood 20101007

• Metabolization of nifurtimox and benznidazole in cellular fractions of rat mammary tissue.

  Human & experimental toxicology 20101001

• The mixed lineage nature of nitrogen transport and assimilation in marine eukaryotic phytoplankton: a case study of micromonas.

  Molecular biology and evolution 20101001

• Purine metabolite levels in preovulatory human follicles may hold the key to ovarian hyperstimulation syndrome.

  Metabolism: clinical and experimental 20101001

• Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: biological activities and selective toxicities.

  Biochemical pharmacology 20101001

• Extreme nucleoside concentrations in a marine annelid: a novel nucleoside storing cell in the polychaete Nereis virens.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20101001

• [Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?].

  Der Nervenarzt 20101001

• Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease.

  Journal of periodontal research 20101001

• Vaccinations in patients with immune-mediated inflammatory diseases.

  Rheumatology (Oxford, England) 20101001

• Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: a target for anti-malarial chemotherapy.

  Molecular and biochemical parasitology 20101001

• Two nucleoside transporters in Lactococcus lactis with different substrate specificities.

  Microbiology (Reading, England) 20101001

• Editing site analysis in a gymnosperm mitochondrial genome reveals similarities with angiosperm mitochondrial genomes.

  Current genetics 20101001

• Extracellular nucleotides elicit cytosolic free calcium oscillations in Arabidopsis.

  Plant physiology 20101001

• Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells.

  The Journal of biological chemistry 20101001

• Substrate specificity and nucleotides binding properties of NM23H2/nucleoside diphosphate kinase homolog from Plasmodium falciparum.

  Journal of bioenergetics and biomembranes 20101001

• Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria.

  Journal of biochemistry 20101001

• Upstream open reading frames: molecular switches in (patho)physiology.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20101001

• Growth of wildtype and mutant E. coli strains in minimal media for optimal production of nucleic acids for preparing labeled nucleotides.

  Applied microbiology and biotechnology 20101001

• Purine restriction induces pronounced translational upregulation of the NT1 adenosine/pyrimidine nucleoside transporter in Leishmania major.

  Molecular microbiology 20101001

• Enzyme catalysis from improved packing in their transition-state structures.

  Current opinion in chemical biology 20101001

• Investigation of riboflavin sensitized degradation of purine and pyrimidine derivatives of DNA and RNA under UVA and UVB.

  Biochemical and biophysical research communications 20101001

• Modelling the effects of inhibitors of guanine nucleotide synthesis: implications for studies of cellular differentiation pathways.

  Biochemical Society transactions 20101001

• Uric acid and the development of hypertension.

  Medical science monitor : international medical journal of experimental and clinical research 20101001

• Adaptive responses to purine starvation in Leishmania donovani.

  Molecular microbiology 20101001

• Rituximab plus fludarabine and cyclophosphamide or other agents in chronic lymphocytic leukemia.

  Expert review of anticancer therapy 20101001

• Pharmacological properties and physiological function of a P2X-like current in single proximal tubule cells isolated from frog kidney.

  The Journal of membrane biology 20101001

• Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite.

  PLoS pathogens 20101001

• 9-(1,1-Dimethyl-3-oxobut-yl)adenine.

  Acta crystallographica. Section E, Structure reports online 20101001

• Adenosine Deaminase Levels in CSF of Tuberculous Meningitis Patients.

  Journal of clinical medicine research 20101001

• Synthesis and early development of hexadecyloxypropylcidofovir: an oral antipoxvirus nucleoside phosphonate.

  Viruses 20101001

• Discovery of new inhibitors of Schistosoma mansoni PNP by pharmacophore-based virtual screening.

  Journal of chemical information and modeling 20100927

• Excited state behaviour of substituted dipyridophenazine Cr(III) complexes in the presence of nucleic acids.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100924

• Design and synthesis of potent 'sulfur-free' transition state analogue inhibitors of 5'-methylthioadenosine nucleosidase and 5'-methylthioadenosine phosphorylase.

  Journal of medicinal chemistry 20100923

• Phytochemicals from Acacia confusa heartwood extracts reduce serum uric acid levels in oxonate-induced mice: their potential use as xanthine oxidase inhibitors.

  Journal of agricultural and food chemistry 20100922

• Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.

  Bioorganic & medicinal chemistry 20100915

• Studies on ligand binding to histidine triad nucleotide binding protein 1.

  Bioorganic & medicinal chemistry 20100915

• RNA tetraloop folding reveals tension between backbone restraints and molecular interactions.

  Journal of the American Chemical Society 20100915

• Synthesis of cyclic di-nucleotidic acids as potential inhibitors targeting diguanylate cyclase.

  Bioorganic & medicinal chemistry 20100915

• Rapid determination of adenosine deaminase kinetics using fast-scan cyclic voltammetry.

  Physical chemistry chemical physics : PCCP 20100914

• Targeting of an interrupted polypurine:polypyrimidine sequence in mammalian cells by a triplex-forming oligonucleotide containing a novel base analogue.

  Biochemistry 20100914

• Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells.

  Science (New York, N.Y.) 20100910

• TRAIL treatment provokes mutations in surviving cells.

  Oncogene 20100909

• The anionic (9-methyladenine)-(1-methylthymine) base pair solvated by formic acid. A computational and photoelectron spectroscopy study.

  The journal of physical chemistry. B 20100902

• Changes in stone composition according to age in Tunisian pediatric patients.

  International urology and nephrology 20100901

• Triazophos up-regulated gene expression in the female brown planthopper, Nilaparvata lugens.

  Journal of insect physiology 20100901

• Theacrine, a purine alkaloid with anti-inflammatory and analgesic activities.

  Fitoterapia 20100901

• Decreased kidney function and crystal deposition in the tubules after kidney transplant.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20100901

• A population-based study of health-care resource use among infliximab users.

  The American journal of gastroenterology 20100901

• Characterization of mammalian equilibrative nucleoside transporters (ENTs) by mass spectrometry.

  Protein expression and purification 20100901

• Lower frequency of the low activity adenosine deaminase allelic variant (ADA1*2) in schizophrenic patients.

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20100901

• Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease.

  Acta neuropathologica 20100901

• Acute effect of milk on serum urate concentrations: a randomised controlled crossover trial.

  Annals of the rheumatic diseases 20100901

• Mizoribine attenuates renal injury and macrophage infiltration in patients with severe lupus nephritis.

  Clinical rheumatology 20100901

• Blood uridine concentration may be an indicator of the degradation of pyrimidine nucleotides during physical exercise with increasing intensity.

  Journal of physiology and biochemistry 20100901

• Nucleoside/nucleobase transport and metabolism by microvascular endothelial cells isolated from ENT1-/- mice.

  American journal of physiology. Heart and circulatory physiology 20100901

• Purine bases oxidation and repair following permethrin insecticide treatment in rat heart cells.

  Cardiovascular toxicology 20100901

• Mining metabolic pathways through gene expression.

  Bioinformatics (Oxford, England) 20100901

• Terminal restriction fragment length measurement errors are affected mainly by fragment length, G+C nucleotide content and secondary structure melting point.

  Journal of microbiological methods 20100901

• Chemoimmunotherapy of chronic lymphocytic leukemia.

  Nature reviews. Clinical oncology 20100901

• LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells.

  Leukemia 20100901

• Role of adenosine kinase in cochlear development and response to noise.

  Journal of neuroscience research 20100901

• Novel nucleosides as potent influenza viral inhibitors.

  Bioorganic & medicinal chemistry 20100901

• Extracellular-purine metabolism in blood vessels (part I). Extracellular-purine level in blood of patients with abdominal aortic aneurysm.

  Nucleosides, nucleotides & nucleic acids 20100901

• Nucleoside transport and associated metabolism.

  Plant biology (Stuttgart, Germany) 20100901

• Distribution of purine nucleotides in uremic fluids and tissues.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20100901

• World Congress on the Insulin Resistance Syndrome, 2009: the kidney, the liver, and insulin resistance.

  Diabetes care 20100901

• Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracis.

  Acta crystallographica. Section D, Biological crystallography 20100901

• Late-onset neutropenia after rituximab treatment: case series and comprehensive review of the literature.

  Medicine 20100901

• Combination of uric acid and NT-ProBNP: a more useful prognostic marker for short-term clinical outcomes in patients with acute heart failure.

  The Korean journal of internal medicine 20100901

• Folic Acid supplementation stimulates notch signaling and cell proliferation in embryonic neural stem cells.

  Journal of clinical biochemistry and nutrition 20100901

• Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii.

  PLoS genetics 20100901

• The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution.

  PLoS pathogens 20100901

• A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division.

  PLoS pathogens 20100901

• 2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides.

  Chemistry & biodiversity 20100901

• Sustained long-term remissions with weekly interferon maintenance therapy in hairy cell leukemia.

  Asia-Pacific journal of clinical oncology 20100901

• Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

  PLoS computational biology 20100901

• Biosensor measurement of purine release from cerebellar cultures and slices.

  Purinergic signalling 20100901

• Genomic and epigenomic instability, fragile sites, schizophrenia and autism.

  Current genomics 20100901

• Novel N-methylated 8-oxoisoguanines from Pacific sponges with diverse neuroactivities.

  Journal of medicinal chemistry 20100826

• Quercetin induced apoptosis in association with death receptors and fludarabine in cells isolated from chronic lymphocytic leukaemia patients.

  British journal of cancer 20100824

• Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis.

  Current biology : CB 20100824

• Antifolate-induced depletion of intracellular glycine and purines inhibits thymineless death in E. coli.

  ACS chemical biology 20100820

• Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.

  Blood 20100819

• Increased uric acid levels in drug-naïve subjects with bipolar disorder during a first manic episode.

  Progress in neuro-psychopharmacology & biological psychiatry 20100816

• Determination of cisplatin 1,2-intrastrand guanine-guanine DNA adducts in human leukocytes by high-performance liquid chromatography coupled to inductively coupled plasma mass spectrometry.

  Chemical research in toxicology 20100816

• The relationship between oxygen and adenosine in astrocytic cultures.

  Glia 20100815

• Direct voltammetric analysis of DNA modified with enzymatically incorporated 7-deazapurines.

  Analytical chemistry 20100815

• Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia.

  Blood 20100812

• CycloSal-phosphate pronucleotides of cytostatic 6-(Het)aryl-7-deazapurine ribonucleosides: Synthesis, cytostatic activity, and inhibition of adenosine kinases.

  ChemMedChem 20100802

• Purine analogs sensitize the multidrug resistant cell line (NCI-H460/R) to doxorubicin and stimulate the cell growth inhibitory effect of verapamil.

  Investigational new drugs 20100801

• Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome.

  Journal of medical genetics 20100801

• Changes in stone composition according to age and gender in Tunisian children.

  Journal of pediatric urology 20100801

• DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma.

  Cancer chemotherapy and pharmacology 20100801

• A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.

  Cancer chemotherapy and pharmacology 20100801

• l-Carnitine l-tartrate supplementation favorably affects biochemical markers of recovery from physical exertion in middle-aged men and women.

  Metabolism: clinical and experimental 20100801

• High follicular fluid adenosine levels may be pivotal in the metabolism and recycling of adenosine nucleotides in the human follicle.

  Metabolism: clinical and experimental 20100801

• Comparative analysis of the extracellular proteomes of two Clostridium sordellii strains exhibiting contrasting virulence.

  Anaerobe 20100801

• Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100801

• Homology modeling and docking study of xanthine oxidase of Arthrobacter sp. XL26.

  International journal of biological macromolecules 20100801

• Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution.

  Environmental health perspectives 20100801

• Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA).

  Environmental health perspectives 20100801

• Role of Hfq in iron-dependent and -independent gene regulation in Neisseria meningitidis.

  Microbiology (Reading, England) 20100801

• The purinergic P2Y(13) receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death.

  Free radical biology & medicine 20100801

• The effect of spermine concentration on the solution structure of complexes formed in copper(II)/adenosine 5'-triphosphate/phosphoserine system.

  Journal of inorganic biochemistry 20100801

• Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways.

  The Journal of pharmacology and experimental therapeutics 20100801

• Uric acid increases fibronectin synthesis through upregulation of lysyl oxidase expression in rat renal tubular epithelial cells.

  American journal of physiology. Renal physiology 20100801

• Gene silencing of transgenes inserted in the Aspergillus nidulans alcM and/or alcS loci.

  Current genetics 20100801

• Accumulation of gene-targeted Bacillus subtilis mutations that enhance fermentative inosine production.

  Applied microbiology and biotechnology 20100801

• Design and directed evolution of a dideoxy purine nucleoside phosphorylase.

  Protein engineering, design & selection : PEDS 20100801

• Enzymatic synthesis of 2'-deoxyadenosine and 6-methylpurine-2'-deoxyriboside by Escherichia coli DH5alpha overexpressing nucleoside phosphorylases from Escherichia coli BL21.

  Journal of bioscience and bioengineering 20100801

• Simultaneous determination of nucleosides and nucleotides in dietary foods and beverages using ion-pairing liquid chromatography-electrospray ionization-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100801

• Transcriptional profiles of drought-responsive genes in modulating transcription signal transduction, and biochemical pathways in tomato.

  Journal of experimental botany 20100801

• Fructose induces transketolase flux to promote pancreatic cancer growth.

  Cancer research 20100801

• Nitrogen utilization, nutrient digestibility, and excretion of purine derivatives in dairy cattle consuming rations containing corn milling co-products.

  Journal of dairy science 20100801

• Effects of timing of corn silage supplementation on digestion, fermentation pattern, and nutrient flow during continuous culture fermentation of a short and intensive orchardgrass meal.

  Journal of dairy science 20100801

• The role of the formamide/zirconia system in the synthesis of nucleobases and biogenic carboxylic acid derivatives.

  Journal of molecular evolution 20100801

• Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of SAICAR synthase from Streptococcus suis serotype 2.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20100801

• Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery.

  Acta crystallographica. Section D, Biological crystallography 20100801

• Lysine120 interactions with p53 response elements can allosterically direct p53 organization.

  PLoS computational biology 20100801

• A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase.

  PLoS neglected tropical diseases 20100801

• A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol.

  PLoS neglected tropical diseases 20100801

• Forodesine: review of preclinical and clinical data.

  Future oncology (London, England) 20100801

• Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

  PLoS neglected tropical diseases 20100801

• Functional genome annotation by combined analysis across microarray studies of Trypanosoma brucei.

  PLoS neglected tropical diseases 20100801

• [Xanthinuria type I as the cause of nephrolithiasis in 17-years old girl].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20100801

• A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.

  PLoS pathogens 20100801

• Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway.

  PLoS genetics 20100801

• Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols.

  Nutrients 20100801

• Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90.

  Chemistry & biology 20100730

• SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding.

  Journal of molecular biology 20100723

• A medicinal chemist's guide to molecular interactions.

  Journal of medicinal chemistry 20100722

• Radiation-induced formation of purine 5',8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen.

  Organic & biomolecular chemistry 20100721

• Metal ion-binding properties of 9-[(2-phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antiviral nucleotide analogue 9-[(2-phosphonomethoxy)ethyl]adenine (PMEA). Steric guiding of metal ion-coordination by the purine-amino group.

  Dalton transactions (Cambridge, England : 2003) 20100721

• Products of the direct reaction of the diazonium ion of a metabolite of the carcinogen N-nitrosomorpholine with purines of nucleosides and DNA.

  Chemical research in toxicology 20100719

• Enhanced functional potential of nucleic acid aptamer libraries patterned to increase secondary structure.

  Journal of the American Chemical Society 20100714

• RNA internal loops with tandem AG pairs: the structure of the 5'GAGU/3'UGAG loop can be dramatically different from others, including 5'AAGU/3'UGAA.

  Biochemistry 20100713

• PfNT2, a permease of the equilibrative nucleoside transporter family in the endoplasmic reticulum of Plasmodium falciparum.

  The Journal of biological chemistry 20100702

• Methotrexate for maintenance of remission in chronic active Crohn's disease: long-term single-center experience and meta-analysis of observational studies.

  Inflammatory bowel diseases 20100701

• Use of the growing environment as a source of variation to identify the quantitative trait transcripts and modules of co-expressed genes that determine chlorogenic acid accumulation.

  Plant, cell & environment 20100701

• Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.

  Molecular and biochemical parasitology 20100701

• A forward genetic screen to explore chloroplast protein import in vivo identifies Moco sulfurase, pivotal for ABA and IAA biosynthesis and purine turnover.

  The Plant journal : for cell and molecular biology 20100701

• Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes--a novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies.

  International immunopharmacology 20100701

• Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis.

  The FEBS journal 20100701

• Cytotoxic activity of 2-Fluoro-ara-AMP and 2-Fluoro-ara-AMP-loaded erythrocytes against human breast carcinoma cell lines.

  International journal of oncology 20100701

• Glycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery.

  Expert opinion on therapeutic targets 20100701

• Treatment of patients with fludarabine-refractory chronic lymphocytic leukemia: need for new treatment options.

  Leukemia & lymphoma 20100701

• Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.

  The FEBS journal 20100701

• Proteomic changes associated with expression of a gene (ipt) controlling cytokinin synthesis for improving heat tolerance in a perennial grass species.

  Journal of experimental botany 20100701

• Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry 20100701

• Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase.

  Bioorganic & medicinal chemistry 20100701

• SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence.

  Aging 20100701

• Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides.

  Bioorganic & medicinal chemistry 20100701

• Utilization of nitrogen in cows consuming wet distillers grains with solubles in alfalfa and corn silage-based dairy rations.

  Journal of dairy science 20100701

• Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes.

  PLoS computational biology 20100701

• Determination of serum adenosine deaminase and xanthine oxidase levels in patients with crimean-congo hemorrhagic fever.

  Clinics (Sao Paulo, Brazil) 20100701

• [Plasma antioxidant activity--a test for impaired biological functions of endoecology, exotrophy, and inflammation reactions].

  Klinicheskaia laboratornaia diagnostika 20100701

• Susceptibility to mycobacterial infection in a young man with a hypoglossal nerve palsy: the hunt for an immunological defect.

  JRSM short reports 20100701

• 7-(5-Methyl-sulfanyl-β-d-erythrofuran-osyl)-7H-pyrrolo-[2,3-d]pyrimidin-4-amine monohydrate (MT-tubercidin·H(2)O).

  Acta crystallographica. Section E, Structure reports online 20100701

• 2-(Bicyclo-[2.2.1]hept-5-en-2-yl)-1H-pyrrolo-[2,3-b]pyridine.

  Acta crystallographica. Section E, Structure reports online 20100701

• New trends in nucleoside biotechnology.

  Acta naturae 20100701

• Encapsulation of nucleotides and DNA into Mg-Al layered double hydroxide.

  International journal of pharmaceutics 20100630

• Short peptide nucleic acids bind strongly to homopurine tract of double helical RNA at pH 5.5.

  Journal of the American Chemical Society 20100630

• Photodynamic therapy for multi-resistant cutaneous Langerhans cell histiocytosis.

  Rare tumors 20100630

• Probing the probes: fitness factors for small molecule tools.

  Chemistry & biology 20100625

• Assembly mechanism of the sixty-subunit nanoparticles via interaction of RNA with the reengineered protein connector of phi29 DNA-packaging motor.

  ACS nano 20100622

• Purine substrate recognition by the nucleobase-ascorbate transporter signature motif in the YgfO xanthine permease: ASN-325 binds and ALA-323 senses substrate.

  The Journal of biological chemistry 20100618

• The primary role of glutathione against nuclear DNA damage of striatum induced by permethrin in rats.

  Neuroscience 20100616

• Synthesis and evaluation of in vitro anticancer activity of some novel isopentenyladenosine derivatives.

  Bioorganic & medicinal chemistry 20100615

• Guanine, adenine, and hypoxanthine production in UV-irradiated formamide solutions: relaxation of the requirements for prebiotic purine nucleobase formation.

  Chembiochem : a European journal of chemical biology 20100614

• Seasonal variations in skin pigmentation and flesh quality of Atlantic salmon ( Salmo salar L.): implications for quality management.

  Journal of agricultural and food chemistry 20100609

• Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.

  DNA repair 20100604

• Increase in urinary purines and pyrimidines in patients with methylmalonic aciduria combined with homocystinuria.

  Clinica chimica acta; international journal of clinical chemistry 20100603

• Strong inhibition of replicative DNA synthesis in the developing rat cerebral cortex and glioma cells by roscovitine.

  Investigational new drugs 20100601

• Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes.

  Environmental health perspectives 20100601

• 'Clinical features of women with gout arthritis.' A systematic review.

  Clinical rheumatology 20100601

• The evolutionary fate of the genes encoding the purine catabolic enzymes in hominoids, birds, and reptiles.

  Molecular biology and evolution 20100601

• The proteome of Shigella flexneri 2a 2457T grown at 30 and 37 degrees C.

  Molecular & cellular proteomics : MCP 20100601

• Trichomonas vaginalis nucleoside triphosphate diphosphohydrolase and ecto-5'-nucleotidase activities are inhibited by lycorine and candimine.

  Parasitology international 20100601

• Uric acid does not affect the acetylcholine-induced relaxation of aorta from normotensive and deoxycorticosterone acetate-salt hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20100601

• Complete assignment of the (1)H and (13)C NMR spectra of cis and trans isonucleoside derivatives of purine with a tetrahydropyran ring.

  Magnetic resonance in chemistry : MRC 20100601

• Combinatorial-computational-chemoinformatics (C3) approach to finding and analyzing low-energy tautomers.

  Journal of computer-aided molecular design 20100601

• Triuret as a potential hypokalemic agent: Structure characterization of triuret and triuret-alkali metal adducts by mass spectrometric techniques.

  Archives of biochemistry and biophysics 20100601

• Role of wake-promoting basal forebrain and adenosinergic mechanisms in sleep-promoting effects of ethanol.

  Alcoholism, clinical and experimental research 20100601

• A direct NMR method for the measurement of competitive kinetic isotope effects.

  Nature chemical biology 20100601

• Bioinformatic, structural, and functional analyses support release factor-like MTRF1 as a protein able to decode nonstandard stop codons beginning with adenine in vertebrate mitochondria.

  RNA (New York, N.Y.) 20100601

• Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.

  Bioorganic & medicinal chemistry 20100601

• Large-scale transposon mutagenesis of photosynthetic Bradyrhizobium sp. strain ORS278 reveals new genetic loci putatively important for nod-independent symbiosis with Aeschynomene indica.

  Molecular plant-microbe interactions : MPMI 20100601

• Targeting Plasmodium falciparum purine salvage enzymes: a look at structure-based drug development.

  Infectious disorders drug targets 20100601

• Uric acid transport and disease.

  The Journal of clinical investigation 20100601

• Synthesis of 2'-deoxyoxanosine from 2'-deoxyguanosine, conversion to its phosphoramidite, and incorporation into oxanine-containing oligodeoxynucleotides.

  Current protocols in nucleic acid chemistry 20100601

• Retraction: Purine and pyrimidine derivatives from the South China Sea gorgonian Subergorgia suberosa[Chem. Pharm. Bull. 56(7): 993-994 (2008)].

  Chemical & pharmaceutical bulletin 20100601

• Two lung masses with different responses to pemetrexed.

  The Korean journal of internal medicine 20100601

• Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall.

  PLoS neglected tropical diseases 20100601

• Purine and pyrimidine metabolism in the fist decade of the 21st century--highlights and perspectives.

  Nucleosides, nucleotides & nucleic acids 20100601

• Molecular analysis of two enzyme genes, HPRT1 and PRPS1, causing X-linked inborn errors of purine metabolism.

  Nucleosides, nucleotides & nucleic acids 20100601

• Partial HPRT deficiency phenotype and incomplete splicing mutation.

  Nucleosides, nucleotides & nucleic acids 20100601

• Delayed treatment effects of xanthine oxidase inhibition on systolic overload-induced left ventricular hypertrophy and dysfunction.

  Nucleosides, nucleotides & nucleic acids 20100601

• Nucleoside phosphorylases from clostridium perfringens in the synthesis of 2',3'-dideoxyinosine.

  Nucleosides, nucleotides & nucleic acids 20100601

• Identification of purine nucleoside phosphorylase deficiency in dried blood spots by a non-radiochemical assay using reversed-phase high-performance liquid chromatography.

  Nucleosides, nucleotides & nucleic acids 20100601

• Analysis of purine in purine-rich cauliflower.

  Nucleosides, nucleotides & nucleic acids 20100601

• Lesch-Nyhan variant syndrome: variable presentation in 3 affected family members.

  Archives of neurology 20100601

• Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism.

  PLoS neglected tropical diseases 20100601

• [Research advance on fludarabine resistance mechanisms in chronic lymphocytic leukemia cells].

  Zhongguo shi yan xue ye xue za zhi 20100601

• Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat.

  PLoS biology 20100601

• Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.

  PLoS neglected tropical diseases 20100601

• Sequence signatures of nucleosome positioning in Caenorhabditis elegans.

  Genomics, proteomics & bioinformatics 20100601

• The history of National Purine Clubs and the International Purine Club.

  Purinergic signalling 20100601

• Novel treatment regimens for Waldenström's macroglobulinemia.

  Expert review of hematology 20100601

• Allogeneic hematopoietic cell transplantation for acute leukemia in first relapse or second remission.

  The Korean journal of hematology 20100601

• Fludarabine-based myeloablative regimen as pretransplant conditioning therapy in adult acute leukemia/myelodysplastic syndrome: comparison with oral or intravenous busulfan with cyclophosphamide.

  The Korean journal of hematology 20100601

• 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy-ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione.

  Acta crystallographica. Section E, Structure reports online 20100601

• Sensitivity, specificity, negative and positive predictive values of adenosine deaminase in patients of tubercular and non-tubercular serosal effusion in India.

  Journal of clinical medicine research 20100601

• Historical perspectives in the development of antiviral agents against poxviruses.

  Viruses 20100601

• Molecular mechanism of ochratoxin a transport in the kidney.

  Toxins 20100601

• Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).

  The Journal of biological chemistry 20100528

• Structural assignment of 6-oxy purine derivatives through computational modeling, synthesis, X-ray diffraction, and spectroscopic analysis.

  The journal of physical chemistry. B 20100527

• Photochemical synthesis of nucleoside analogues from cyclobutanones: bicyclic and isonucleosides.

  Molecules (Basel, Switzerland) 20100526

• Asymmetric allosteric signaling in aspartate transcarbamoylase.

  ACS chemical biology 20100521

• Silver-catalyzed intramolecular cyclization of 9-propargyladenine via N3 alkylation.

  Chemical communications (Cambridge, England) 20100521

• Replication through an abasic DNA lesion: structural basis for adenine selectivity.

  The EMBO journal 20100519

• Noncirrhotic portal hypertension in HIV-infected patients: unique clinical and pathological findings.

  AIDS (London, England) 20100515

• The synthesis of novel fluorescent purine analogues modified by azacrown ether at C6.

  Bioorganic & medicinal chemistry letters 20100515

• Mass spectrometry and renal calculi.

  Journal of medicine and life 20100515

• Reactogenicity and immunogenicity of live attenuated Salmonella enterica serovar Paratyphi A enteric fever vaccine candidates.

  Vaccine 20100507

• Determinants of sequence-specificity within human AID and APOBEC3G.

  DNA repair 20100504

• Heterogeneity and dynamics of the ligand recognition mode in purine-sensing riboswitches.

  Biochemistry 20100504

• Idiopathic immunoglobulin A nephropathy in children and adolescents.

  Pediatric nephrology (Berlin, Germany) 20100501

• Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites.

  Molecular diversity 20100501

• Effects of extracellular purines on cytotoxicity of methotrexate.

  Cancer chemotherapy and pharmacology 20100501

• Mismatch-induced lethality due to a defect in Escherichia coli RecQ helicase in exonuclease-deficient background: Dependence on MutS and UvrD functions.

  Plasmid 20100501

• Ischaemic preconditioning is related to decreasing levels of extracellular adenosine that may be metabolically useful in the at-risk myocardium: an experimental study in the pig.

  Acta physiologica (Oxford, England) 20100501

• Testing the theory of immune selection in cancers that break the rules of transplantation.

  Cancer immunology, immunotherapy : CII 20100501

• Enhanced cyclic adenosine monophosphate production by Arthrobacter A302 through rational redistribution of metabolic flux.

  Bioresource technology 20100501

• Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20100501

• Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor.

  Acta tropica 20100501

• P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons.

  Cellular and molecular life sciences : CMLS 20100501

• Metal ion-N7 coordination in a ribozyme branch domain by NMR.

  Journal of inorganic biochemistry 20100501

• Assessing the chemical diversity of an hsp90 database.

  European journal of medicinal chemistry 20100501

• Presynaptic inhibition of neural vasodilator pathways to submucosal arterioles by release of purines from sympathetic nerves.

  American journal of physiology. Gastrointestinal and liver physiology 20100501

• Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia.

  Cancer 20100501

• Cytokinin receptor antagonists derived from 6-benzylaminopurine.

  Phytochemistry 20100501

• Site-specific labeling of nucleotides for making RNA for high resolution NMR studies using an E. coli strain disabled in the oxidative pentose phosphate pathway.

  Journal of biomolecular NMR 20100501

• PathWave: discovering patterns of differentially regulated enzymes in metabolic pathways.

  Bioinformatics (Oxford, England) 20100501

• Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation.

  Nature chemical biology 20100501

• Applications of cold temperature stress to age fractionate Caenorhabditis elegans: a simple inexpensive technique.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20100501

• Disordered lymphoid purine metabolism contributes to the pathogenesis of persistent Borrelia garinii infection in mice.

  Journal of immunology (Baltimore, Md. : 1950) 20100501

• Effects of partial replacement of concentrate with feed blocks on nutrient utilization, microbial N flow, and milk yield and composition in goats.

  Journal of dairy science 20100501

• Selective induction of astrocytic gliosis generates deficits in neuronal inhibition.

  Nature neuroscience 20100501

• Correlates of the severity of coronary atherosclerosis in long-term kidney transplant patients.

  Journal of Korean medical science 20100501

• Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans.

  PLoS genetics 20100501

• 'Manifesto' for advancing the control and elimination of neglected tropical diseases.

  PLoS neglected tropical diseases 20100501

• microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection.

  Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 20100501

• 2-Chloro-9-isopropyl-N,N-dimethyl-9H-purin-6-amine.

  Acta crystallographica. Section E, Structure reports online 20100501

• Effects of mixtures of red clover and maize silages on the partitioning of dietary nitrogen between milk and urine by dairy cows.

  Animal : an international journal of animal bioscience 20100501

• Regulation of FGF1 gene promoter through transcription factor RFX1.

  The Journal of biological chemistry 20100430

• Changes in purines concentration in the cerebrospinal fluid of patients experiencing pain: a case-control study.

  Neuroscience letters 20100426

• Novel nucleobase-simplified cyclic ADP-ribose analogue: A concise synthesis and Ca(2+)-mobilizing activity in T-lymphocytes.

  Organic & biomolecular chemistry 20100421

• The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization.

  The Journal of biological chemistry 20100416

• Hopping enables a DNA repair glycosylase to search both strands and bypass a bound protein.

  ACS chemical biology 20100416

• Azide-tetrazole equilibrium of C-6 azidopurine nucleosides and their ligation reactions with alkynes.

  The Journal of organic chemistry 20100416

• Preparation of cyclonucleosides.

  Chemical reviews 20100414

• A unique fluorescent base analogue for the expansion of the genetic alphabet.

  Journal of the American Chemical Society 20100414

• Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis.

  Biochemistry 20100413

• Comparison of cladribine plus cyclophosphamide with fludarabine plus cyclophosphamide as first-line therapy for chronic lymphocytic leukemia: a phase III randomized study by the Polish Adult Leukemia Group (PALG-CLL3 Study).

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410

• The NPH-II helicase displays efficient DNA x RNA helicase activity and a pronounced purine sequence bias.

  The Journal of biological chemistry 20100409

• Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2.

  The Journal of biological chemistry 20100409

• PRPS1 mutations: four distinct syndromes and potential treatment.

  American journal of human genetics 20100409

• Intramolecular direct C-H arylation approach to fused purines. Synthesis of purino[8,9-f]phenanthridines and 5,6-dihydropurino[8,9-a]isoquinolines.

  The Journal of organic chemistry 20100402

• Significant efficacy of 2-CdA with or without rituximab in the treatment of splenic marginal zone lymphoma (SMZL).

  Annals of oncology : official journal of the European Society for Medical Oncology 20100401

• Role of adenosine A2 receptors in regulation of cerebral blood flow during induced hypotension.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100401

• Reversine enhances generation of progenitor-like cells by dedifferentiation of annulus fibrosus cells.

  Tissue engineering. Part A 20100401

• Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores.

  Microbiology (Reading, England) 20100401

• Isoprinosine affects serum cytokine levels in healthy adults.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20100401

• The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, (57)Fe Mössbauer), theoretical, and biological activity studies.

  Journal of inorganic biochemistry 20100401

• Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells.

  Chemical biology & drug design 20100401

• A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease.

  American journal of physiology. Renal physiology 20100401

• Vital role of protein kinase C-related kinase in the formation and stability of neurites during hypoxia.

  Journal of neurochemistry 20100401

• Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma.

  The Journal of pathology 20100401

• The efficacy and stem cell toxicity of cladribine and rituximab in the treatment of patients with chronic lymphocytic leukemia: are all purine analogs created equal?

  Leukemia & lymphoma 20100401

• Fast and automated functional classification with MED-SuMo: an application on purine-binding proteins.

  Protein science : a publication of the Protein Society 20100401

• The pharmacological role of nucleotidases in snake venoms.

  Cell biochemistry and function 20100401

• 9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase.

  The FEBS journal 20100401

• New targets of therapy in T-cell lymphomas.

  Current drug targets 20100401

• 1H-, 13C-, and 15N-NMR chemical shifts for selected glucosides and ribosides of aromatic cytokinins.

  Magnetic resonance in chemistry : MRC 20100401

• 1H and 13C resonance assignments of a guanine sensing riboswitch's terminator hairpin.

  Biomolecular NMR assignments 20100401

• Purine derivatives as potent gamma-secretase modulators.

  Bioorganic & medicinal chemistry letters 20100401

• Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives.

  Journal of enzyme inhibition and medicinal chemistry 20100401

• Treatment of autoimmune cytopenia complicating progressive chronic lymphocytic leukemia/small lymphocytic lymphoma with rituximab, cyclophosphamide, vincristine, and prednisone.

  Leukemia & lymphoma 20100401

• Treatment of splenic marginal zone lymphoma: splenectomy versus rituximab.

  Seminars in hematology 20100401

• Novel agents in development for peripheral T-cell lymphoma.

  Seminars in hematology 20100401

• Clinical trials for human T-cell lymphotropic virus type I-associated peripheral T-cell lymphoma in Japan.

  Seminars in hematology 20100401

• Novel therapies for myelodysplastic syndromes.

  Hematology/oncology clinics of North America 20100401

• GTPase activity plays a key role in the pathobiology of LRRK2.

  PLoS genetics 20100401

• Chronic lymphocytic leukemia: putting new treatment options into perspective.

  Cancer control : journal of the Moffitt Cancer Center 20100401

• A microarray-based genetic screen for yeast chronological aging factors.

  PLoS genetics 20100401

• Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways.

  PLoS pathogens 20100401

• Ribonucleotides.

  Cold Spring Harbor perspectives in biology 20100401

• [Fungal infections in oncohematology: the role of prophylaxis].

  Drugs of today (Barcelona, Spain : 1998) 20100401

• The antiepileptic effect of Centella asiatica on the activities of Na/K, Mg and Ca-ATPases in rat brain during pentylenetetrazol-induced epilepsy.

  Indian journal of pharmacology 20100401

• Ethyl 1-benzyl-4-hydr-oxy-2-methyl-5-oxopyrrolidine-3-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20100401

• Role of Adenosine Deaminase Estimation in Differentiation of Tuberculous and Non-tuberculous Exudative Pleural Effusions.

  Journal of clinical medicine research 20100401

• Venom proteins of the parasitoid wasp Nasonia vitripennis: recent discovery of an untapped pharmacopee.

  Toxins 20100401

• Selectivity of Enzymatic Conversion of Oligonucleotide Probes during Nucleotide Polymorphism Analysis of DNA.

  Acta naturae 20100401

• Transport characteristics of mouse concentrative nucleoside transporter 1.

  International journal of pharmaceutics 20100330

• Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion.

  Biochemistry 20100330

• Interactions between DNA purines and ruthenium ammine complexes within nanostructured sol-gel silica matrixes.

  The journal of physical chemistry. B 20100325

• Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.

  Biochemistry 20100323

• RNA interference-mediated suppression of xanthine dehydrogenase reveals the role of purine metabolism in drought tolerance in Arabidopsis.

  FEBS letters 20100319

• Intramolecular cation-pi interactions as the driving force to restrict the conformation of certain nucleosides.

  The Journal of organic chemistry 20100319

• Accurate guanine:cytosine discrimination in T4 DNA ligase-based single nucleotide polymorphism analysis using an oxanine-containing ligation fragment.

  Analytical biochemistry 20100315

• Detoxication of sulfur half-mustards by nucleophilic scavengers: robust activity of thiopurines.

  Chemical research in toxicology 20100315

• Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs.

  Bioorganic & medicinal chemistry 20100315

• Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer.

  Structure (London, England : 1993) 20100314

• Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels.

  The Journal of biological chemistry 20100312

• The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase.

  Journal of molecular biology 20100312

• Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).

  Journal of medicinal chemistry 20100311

• Electronic signatures of all four DNA nucleosides in a tunneling gap.

  Nano letters 20100310

• Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues.

  Biochemistry 20100309

• Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation.

  The Journal of organic chemistry 20100305

• Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine.

  Biochemistry 20100302

• Nephrolithiasis related to inborn metabolic diseases.

  Pediatric nephrology (Berlin, Germany) 20100301

• Covalent hydration energies for purine analogs by quantum chemical methods.

  Journal of computational chemistry 20100301

• Purine nucleoside phosphorylase deficiency with fatal course in two sisters.

  European journal of pediatrics 20100301

• Molecular dynamics studies of a hexameric purine nucleoside phosphorylase.

  Journal of molecular modeling 20100301

• Relationship between plasma uridine and urinary urea excretion.

  Metabolism: clinical and experimental 20100301

• Genotoxic effects of neutrophils and hypochlorous acid.

  Mutagenesis 20100301

• Crystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine.

  Journal of structural biology 20100301

• High-throughput binding analysis determines the binding specificity of ASF/SF2 on alternatively spliced human pre-mRNAs.

  Combinatorial chemistry & high throughput screening 20100301

• 1st UK Purine Symposium: 19th November 2009.

  Purinergic signalling 20100301

• The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase.

  Plant physiology 20100301

• Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli formamidopyrimidine DNA glycosylase and endonuclease III.

  Free radical biology & medicine 20100301

• CD154 expression triggered by purine analogues in vitro: Correlation with treatment response and autoimmune events in chronic lymphocytic leukemia.

  Experimental hematology 20100301

• Changing paradigms in the treatment of chronic lymphocytic leukemia.

  Leukemia 20100301

• Equilibrative nucleoside transporter 1 plays an essential role in cardioprotection.

  American journal of physiology. Heart and circulatory physiology 20100301

• The A2aR adenosine receptor controls cytokine production in iNKT cells.

  European journal of immunology 20100301

• The role of oxidative DNA damage, DNA repair, GSTM1, SOD2 and OGG1 polymorphisms in individual susceptibility to Barrett's esophagus.

  Toxicology and industrial health 20100301

• Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36.

  Extremophiles : life under extreme conditions 20100301

• Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans.

  FEMS yeast research 20100301

• Reconstruction of metabolic pathways, protein expression, and homeostasis machineries across maize bundle sheath and mesophyll chloroplasts: large-scale quantitative proteomics using the first maize genome assembly.

  Plant physiology 20100301

• Bioactivity and molecular targets of novel substituted quinolines in murine and human tumor cell lines in vitro.

  International journal of oncology 20100301

• Mechanisms involved in the antinociception induced by systemic administration of guanosine in mice.

  British journal of pharmacology 20100301

• Molecular genetics of attention-deficit/hyperactivity disorder: an overview.

  European child & adolescent psychiatry 20100301

• Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder.

  European child & adolescent psychiatry 20100301

• Attenuated variants of Lesch-Nyhan disease.

  Brain : a journal of neurology 20100301

• Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction.

  Upsala journal of medical sciences 20100301

• Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components.

  Chemical & pharmaceutical bulletin 20100301

• Potential role of uric Acid as a risk factor for cardiovascular disease.

  The Korean journal of internal medicine 20100301

• Computational methods for de novo protein design and its applications to the human immunodeficiency virus 1, purine nucleoside phosphorylase, ubiquitin specific protease 7, and histone demethylases.

  Current drug targets 20100301

• MolDock applied to structure-based virtual screening.

  Current drug targets 20100301

• Separation of purine and pyrimidine bases and nucleosides by hydrophilic interaction chromatography.

  Journal of separation science 20100301

• Xanthine urolithiasis.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100301

• Effects of 5'-adenosine triphosphate on intestinal ischemia-reperfusion in rabbits.

  Transplantation proceedings 20100301

• A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.

  Aging 20100301

• Evidence for the hypothesis that 10-formyldihydrofolate is the in vivo substrate for aminoimidazolecarboxamide ribotide transformylase.

  Experimental biology and medicine (Maywood, N.J.) 20100301

• Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage.

  Nucleosides, nucleotides & nucleic acids 20100301

• Genomic evidence for complementary purine metabolism in the pea aphid, Acyrthosiphon pisum, and its symbiotic bacterium Buchnera aphidicola.

  Insect molecular biology 20100301

• Infectious complications of chronic lymphocytic leukaemia: pathogenesis, spectrum of infection, preventive approaches.

  Best practice & research. Clinical haematology 20100301

• [The importance of vitamin B12 in psychiatry].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20100301

• Complete genomic sequence of bacteriophage felix o1.

  Viruses 20100301

• Mini-exon genotyping of leishmania species in khuzestan province, southwest iran.

  Iranian journal of parasitology 20100301

• Increase in backbone mobility of the VTS1p-SAM domain on binding to SRE-RNA.

  Journal of molecular biology 20100226

• Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2).

  The Journal of biological chemistry 20100226

• Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats.

  European journal of pharmacology 20100225

• Ligand-free copper(I)-catalysed intramolecular direct C-H functionalization of azoles.

  Organic & biomolecular chemistry 20100221

• Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds.

  FEBS letters 20100219

• Chemical basis of nitrogen recovery through the ureide pathway: formation and hydrolysis of S-ureidoglycine in plants and bacteria.

  ACS chemical biology 20100219

• Enzymatic processing of platinated RNAs.

  Journal of the American Chemical Society 20100217

• Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.

  Bioorganic & medicinal chemistry 20100215

• Current and emerging treatment strategies for cutaneous T-cell lymphoma.

  Drugs 20100212

• Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.

  Journal of medicinal chemistry 20100211

• Chlorophenols, chlorocatechols and chloroguaiacols induce DNA base oxidation in human lymphocytes (in vitro).

  Toxicology 20100209

• One-electron oxidation of individual DNA bases and DNA base stacks.

  The journal of physical chemistry. A 20100204

• 13C chemical shift tensors in hypoxanthine and 6-mercaptopurine: effects of substitution, tautomerism, and intermolecular interactions.

  The journal of physical chemistry. A 20100204

• Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate.

  Biochemistry 20100202

• Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase .

  Biochemistry 20100202

• The role of folate receptor alpha (FRalpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy.

  British journal of cancer 20100202

• Association of serum uric acid levels with emotional and affective temperaments.

  Journal of affective disorders 20100201

• Guanosine prevents thermal hyperalgesia in a rat model of peripheral mononeuropathy.

  The journal of pain : official journal of the American Pain Society 20100201

• Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determinants of transporter affinity and selectivity.

  Biochemical pharmacology 20100201

• The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs.

  American journal of physiology. Gastrointestinal and liver physiology 20100201

• The impact of serine/threonine phosphorylation in Staphylococcus aureus.

  International journal of medical microbiology : IJMM 20100201

• Interferon as an alternative to purine analogues in the treatment of hairy cell leukaemia.

  British journal of haematology 20100201

• Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.

  The international journal of biochemistry & cell biology 20100201

• Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity.

  Plant molecular biology 20100201

• Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue.

  Scandinavian journal of clinical and laboratory investigation 20100201

• Pediatric neurological syndromes and inborn errors of purine metabolism.

  Neurochemistry international 20100201

• Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists.

  Bioorganic & medicinal chemistry letters 20100201

• Natural and artificial RNAs occupy the same restricted region of sequence space.

  RNA (New York, N.Y.) 20100201

• Study of inborn errors of metabolism in urine from patients with unexplained mental retardation.

  Journal of inherited metabolic disease 20100201

• Metabolomics in angiotensin II-induced cardiac hypertrophy.

  Hypertension (Dallas, Tex. : 1979) 20100201

• Experimental vaccination of sheep and cattle against tick infestation using recombinant 5'-nucleotidase.

  Parasite immunology 20100201

• Rapid measurements of 2,8-dihydroxyadenine (2,8-DHA) with a nanostructured electrochemical sensor in 5-fold diluted supernatants of endothelial cells exposed to oxidative stress.

  The Analyst 20100201

• Effect of Saccharomyces cerevisiae fermentation product on ruminal fermentation and nutrient utilization in dairy cows.

  Journal of dairy science 20100201

• Association of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) with uric acid among adults with elevated community exposure to PFOA.

  Environmental health perspectives 20100201

• Structure of grouper iridovirus purine nucleoside phosphorylase.

  Acta crystallographica. Section D, Biological crystallography 20100201

• Cloning, expression, purification, crystallization and preliminary X-ray crystallographic study of the putative SAICAR synthetase (PH0239) from Pyrococcus horikoshii OT3.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20100201

• mRNA secondary structures fold sequentially but exchange rapidly in vivo.

  PLoS biology 20100201

• A novel role for Arabidopsis mitochondrial ABC transporter ATM3 in molybdenum cofactor biosynthesis.

  The Plant cell 20100201

• Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease.

  PLoS genetics 20100201

• Genome sequence of the pea aphid Acyrthosiphon pisum.

  PLoS biology 20100201

• Decoupling Environment-Dependent and Independent Genetic Robustness across Bacterial Species.

  PLoS computational biology 20100201

• Interpreting metabolomic profiles using unbiased pathway models.

  PLoS computational biology 20100201

• Design and synthesis of 3'-fluoropenciclovir analogues as antiviral agents.

  Archives of pharmacal research 20100201

• Is there an increased risk of lymphoma and malignancies under anti-TNF therapy in IBD?

  Current drug targets 20100201

• Mucosal healing and anti TNFs in IBD.

  Current drug targets 20100201

• Progressive multifocal leukoencephalopathy in chronic lymphocytic leukemia: a report of three cases and review of the literature.

  Clinical lymphoma, myeloma & leukemia 20100201

• [Molecular cloning, gene expression and characterization of purine nucleoside phosphorylase from Pseudoalteromonas sp. XM2107].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20100201

• Current developments in intraspinal agents for cancer and noncancer pain.

  Current pain and headache reports 20100201

• Microwave-assisted syntheses of nucleosides and their precursors.

  Future medicinal chemistry 20100201

• 6-Amino-9H-purine-1,7-diium bis-(4-methyl-benzene-sulfonate) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20100201

• Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs.

  Journal of medicinal chemistry 20100128

• A comparative study on conformation and ligand binding of the neuronal uncoupling proteins.

  Biochemistry 20100126

• Theoretical study of the mechanism of inhibition of xanthine oxidase by flavonoids and gallic acid derivatives.

  The journal of physical chemistry. B 20100121

• Glycosidase inhibition: assessing mimicry of the transition state.

  Organic & biomolecular chemistry 20100121

• Dynamics of ultrafast singlet and triplet charge transfer in anthraquinone-DNA conjugates.

  Journal of the American Chemical Society 20100120

• Molecular dynamics and quantum mechanics of RNA: conformational and chemical change we can believe in.

  Accounts of chemical research 20100119

• Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells.

  British journal of cancer 20100119

• Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID.

  The Journal of experimental medicine 20100118

• Sensing purine nucleoside phosphorylase activity by using silver nanoparticles.

  Biosensors & bioelectronics 20100115

• Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms.

  Human molecular genetics 20100115

• Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3.

  Journal of molecular biology 20100115

• Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-alpha: Hit to lead studies.

  Bioorganic & medicinal chemistry letters 20100115

• Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.

  Journal of medicinal chemistry 20100114

• Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases.

  Journal of medicinal chemistry 20100114

• 9-Arylpurines as a novel class of enterovirus inhibitors.

  Journal of medicinal chemistry 20100114

• Effects of bioconjugation on the structures and electronic spectra of CdSe: density functional theory study of CdSe-adenine complexes.

  The journal of physical chemistry. B 20100114

• Heat shock protein 90: inhibitors in clinical trials.

  Journal of medicinal chemistry 20100114

• Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.

  Journal of medicinal chemistry 20100114

• Overexpressed proteins may act as mops removing their ligands from the host cells: a case study of calf PNP.

  Biochemical and biophysical research communications 20100108

• How I treat hairy cell leukemia.

  Blood 20100107

• Novel extreme homozygote haplotypes at the human caveolin 1 gene upstream purine complex in sporadic Alzheimer's disease.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20100105

• [Chorea-acanthocytosis without acanthocytes].

  Revue neurologique 20100101

• Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia.

  Glia 20100101

• Ectophosphodiesterase/nucleotide phosphohydrolase (Enpp) nucleotidases: cloning, conservation and developmental restriction.

  The International journal of developmental biology 20100101

• Effects of allopurinol on uric acid concentrations, xanthine oxidoreductase activity and oxidative stress in broiler chickens.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100101

• Deficiency of the housekeeping gene hypoxanthine-guanine phosphoribosyltransferase (HPRT) dysregulates neurogenesis.

  Molecular therapy : the journal of the American Society of Gene Therapy 20100101

• Effects of growth conditions on biofilm formation by Actinobacillus pleuropneumoniae.

  Veterinary research 20100101

• Mutations in the Salmonella enterica serovar Choleraesuis cAMP-receptor protein gene lead to functional defects in the SPI-1 Type III secretion system.

  Veterinary research 20100101

• Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Isotope labeling strategies for NMR studies of RNA.

  Journal of biomolecular NMR 20100101

• Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1.

  Molecular and biochemical parasitology 20100101

• Isolation of an oxalate-resistant Ashbya gossypii strain and its improved riboflavin production.

  Journal of industrial microbiology & biotechnology 20100101

• Effect of xanthine oxidase-generated extracellular superoxide on skeletal muscle force generation.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100101

• The role of chemotherapy and radiation in the treatment of locally advanced non-small cell lung cancer (NSCLC).

  Current drug targets 20100101

• Predictive markers for haematological toxicity of pemetrexed.

  Current drug targets 20100101

• Allium sativum L. extract prevents methyl mercury-induced cytotoxicity in peripheral blood leukocytes (LS).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation.

  The Journal of biological chemistry 20100101

• Monocyclic aromatic amines as potential human carcinogens: old is new again.

  Carcinogenesis 20100101

• Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template.

  Chemical biology & drug design 20100101

• Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches.

  Acta tropica 20100101

• Biomolecular response of oxanine in DNA strands to T4 polynucleotide kinase, T4 DNA ligase, and restriction enzymes.

  Biochemical and biophysical research communications 20100101

• R-roscovitine (Seliciclib) affects CLL cells more strongly than combinations of fludarabine or cladribine with cyclophosphamide: Inhibition of CDK7 sensitizes leukemic cells to caspase-dependent apoptosis.

  Journal of cellular biochemistry 20100101

• Ureide catabolism in Arabidopsis thaliana and Escherichia coli.

  Nature chemical biology 20100101

• 15N and 13C NMR chemical shifts of 6-(fluoro, chloro, bromo, and iodo)purine 2'-deoxynucleosides: measurements and calculations.

  Magnetic resonance in chemistry : MRC 20100101

• The effects of extracellular nucleotides on [Ca2+]i signalling in a human-derived renal proximal tubular cell line (HKC-8).

  Journal of cellular biochemistry 20100101

• The role of Bacillus anthracis germinant receptors in germination and virulence.

  Molecular microbiology 20100101

• 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.

  Biochemical and biophysical research communications 20100101

• Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus.

  Bioorganic & medicinal chemistry letters 20100101

• Protein expression profiling of primary mammary epithelial cells derived from MMTV-neu mice revealed that HER2/NEU-driven changes in protein expression are functionally clustered.

  IUBMB life 20100101

• Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.

  Bioorganic & medicinal chemistry letters 20100101

• Chagas disease: progress and new perspectives.

  Current medicinal chemistry 20100101

• Mitochondrial uncoupling proteins in unicellular eukaryotes.

  Biochimica et biophysica acta 20100101

• Intermediate uveitis.

  Indian journal of ophthalmology 20100101

• Computational study of the interactions between guanine derivatives and cyclin-dependent kinase 2 (CDK2) by CoMFA and QM/MM.

  Journal of chemical information and modeling 20100101

• Aminothiols and allantoin in chronic dialysis patients: effects of hemodialysis sessions.

  Clinical nephrology 20100101

• Histological and genetic markers for non-small-cell lung cancer: customizing treatment based on individual tumor biology.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100101

• Which role for rituximab in hairy cell leukemia? Reflections on six cases.

  Acta haematologica 20100101

• Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

  PLoS computational biology 20100101

• Snake mitochondrial genomes: phylogenetic relationships and implications of extended taxon sampling for interpretations of mitogenomic evolution.

  BMC genomics 20100101

• Malondialdehyde-deoxyguanosine adducts among workers of a Thai industrial estate and nearby residents.

  Environmental health perspectives 20100101

• Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.

  Acta crystallographica. Section D, Biological crystallography 20100101

• Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression.

  BMC genomics 20100101

• Temperature increase prevails over acidification in gene expression modulation of amastigote differentiation in Leishmania infantum.

  BMC genomics 20100101

• [Vesicular ATP transporter: a missing link of purinergic chemical transmission].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100101

• Control of ATP homeostasis during the respiro-fermentative transition in yeast.

  Molecular systems biology 20100101

• Unbiased transcriptional comparisons of generalist and specialist herbivores feeding on progressively defenseless Nicotiana attenuata plants.

  PloS one 20100101

• Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.

  Neural development 20100101

• Remobilization of Tol2 transposons in Xenopus tropicalis.

  BMC developmental biology 20100101

• Exocytosis and protein secretion in Trypanosoma.

  BMC microbiology 20100101

• Transcriptome analysis reveals absence of unintended effects in drought-tolerant transgenic plants overexpressing the transcription factor ABF3.

  BMC genomics 20100101

• Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity.

  BMC biochemistry 20100101

• Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data.

  Genome biology 20100101

• Allosteric regulation of HIV-1 reverse transcriptase by ATP for nucleotide selection.

  PloS one 20100101

• Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human equilibrative nucleoside transporter and the human facilitative nucleobase transporter.

  Malaria journal 20100101

• Global transcriptomic response of Leptospira interrogans serovar Copenhageni upon exposure to serum.

  BMC microbiology 20100101

• Using genomic signatures for HIV-1 sub-typing.

  BMC bioinformatics 20100101

• U87MG decoded: the genomic sequence of a cytogenetically aberrant human cancer cell line.

  PLoS genetics 20100101

• Identification of trkH, encoding a potassium uptake protein required for Francisella tularensis systemic dissemination in mice.

  PloS one 20100101

• The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs.

  PloS one 20100101

• The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions.

  PloS one 20100101

• Comprehensive identification and modified-site mapping of S-nitrosylated targets in prostate epithelial cells.

  PloS one 20100101

• Biochemical characterization of three putative ATPases from a new type IV secretion system of Aeromonas veronii plasmid pAC3249A.

  BMC biochemistry 20100101

• NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3.

  Molecular cancer 20100101

• Synthetic biology: tools to design, build, and optimize cellular processes.

  Journal of biomedicine & biotechnology 20100101

• Expression and functional activity of nucleoside transporters in human choroid plexus.

  Cerebrospinal fluid research 20100101

• The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia.

  Current medicinal chemistry 20100101

• Transposon identification using profile HMMs.

  BMC genomics 20100101

• Role of the gerP operon in germination and outgrowth of Bacillus anthracis spores.

  PloS one 20100101

• Blood lipids, homocysteine, stress factors, and vitamins in clinically stable multiple sclerosis patients.

  Lipids in health and disease 20100101

• Potential and perspectives of cyclonucleosides.

  Current medicinal chemistry 20100101

• Functional characterization of Arabidopsis thaliana transthyretin-like protein.

  BMC plant biology 20100101

• Cloning, purification, and partial characterization of Bacillus subtilis urate oxidase expressed in Escherichia coli.

  Journal of biomedicine & biotechnology 20100101

• Management of hyperuricemia in gout: focus on febuxostat.

  Clinical interventions in aging 20100101

• Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

  PloS one 20100101

• Mycophenolate mofetil-related gastrointestinal mucosal injury in multivisceral transplantation.

  Transplantation proceedings 20100101

• NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity.

  BMC chemical biology 20100101

• Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide.

  BMC genomics 20100101

• Identification of hypoxanthine as a urine marker for non-Hodgkin lymphoma by low-mass-ion profiling.

  BMC cancer 20100101

• Evolutionary history of anglerfishes (Teleostei: Lophiiformes): a mitogenomic perspective.

  BMC evolutionary biology 20100101

• Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath.

  BMC research notes 20100101

• Free energy estimation of short DNA duplex hybridizations.

  BMC bioinformatics 20100101

• Immunobiology of African trypanosomes: need of alternative interventions.

  Journal of biomedicine & biotechnology 20100101

• Identification of functional modules that correlate with phenotypic difference: the influence of network topology.

  Genome biology 20100101

• Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human.

  Biological & pharmaceutical bulletin 20100101

• Lack of association between dietary fructose and hyperuricemia risk in adults.

  Nutrition & metabolism 20100101

• Bioimaging of nucleolin aptamer-containing 5-(N-benzylcarboxyamide)-2'-deoxyuridine more capable of specific binding to targets in cancer cells.

  Journal of biomedicine & biotechnology 20100101

• Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.

  PloS one 20100101

• Global self-regulation of the cellular metabolic structure.

  PloS one 20100101

• Characterization of the octamer, a cis-regulatory element that modulates excretory cell gene-expression in Caenorhabditis elegans.

  BMC molecular biology 20100101

• Treatment rationale and study design for a phase III, double-blind, placebo-controlled study of maintenance pemetrexed plus best supportive care versus best supportive care immediately following induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small cell lung cancer.

  BMC cancer 20100101

• Plasticity of the mitoproteome to nitrogen sources (nitrate and ammonium) in Chlamydomonas reinhardtii: the logic of Aox1 gene localization.

  Biochimica et biophysica acta 20100101

• Depletion of the non-coding regulatory 6S RNA in E. coli causes a surprising reduction in the expression of the translation machinery.

  BMC genomics 20100101

• Genome-wide functional analysis of human 5' untranslated region introns.

  Genome biology 20100101

• Assessment of peripheral blood and bone marrow cells apoptosis caused by purine analogues in patients with chronic lymphocytic leukemia in correlation with parameters of disease progression.

  Acta haematologica 20100101

• Investigating a new generation of ribozymes in order to target HCV.

  PloS one 20100101

• A search for Trypanosoma brucei rhodesiense diagnostic antigens by proteomic screening and targeted cloning.

  PloS one 20100101

• Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes.

  Genome biology 20100101

• Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells.

  Genome biology 20100101

• Phylogenetic analysis of fungal ABC transporters.

  BMC genomics 20100101

• Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach.

  BMC structural biology 20100101

• Valganciclovir in the treatment of cytomegalovirus retinitis in HIV-infected patients.

  Clinical ophthalmology (Auckland, N.Z.) 20100101

• Abacavir/lamivudine combination in the treatment of HIV: a review.

  Therapeutics and clinical risk management 20100101

• The pea aphid genome sequence brings theories of insect defense into question.

  Genome biology 20100101

• Proteome differences associated with fat accumulation in bovine subcutaneous adipose tissues.

  Proteome science 20100101

• Aptamer antagonists of myelin-derived inhibitors promote axon growth.

  PloS one 20100101

• Evolutionary constraints acting on DDX3X protein potentially interferes with Rev-mediated nuclear export of HIV-1 RNA.

  PloS one 20100101

• [The effect of red pigment on amyloidization of yeast proteins].

  Tsitologiia 20100101

• Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production.

  BMC systems biology 20100101

• An overview on nucleases (DNase, RNase, and phosphodiesterase) in snake venoms.

  Biochemistry. Biokhimiia 20100101

• An ab initio and AIM investigation into the hydration of 2-thioxanthine.

  Chemistry Central journal 20100101

• Bacteria in cancer therapy: a novel experimental strategy.

  Journal of biomedical science 20100101

• Efficient activation of reconstructed rat embryos by cyclin-dependent kinase inhibitors.

  PloS one 20100101

• Inhibition of human immunodeficiency virus type-1 by cdk inhibitors.

  AIDS research and therapy 20100101

• Microglia in the aging brain: relevance to neurodegeneration.

  Molecular neurodegeneration 20100101

• The complete multipartite genome sequence of Cupriavidus necator JMP134, a versatile pollutant degrader.

  PloS one 20100101

• Adaptation of group A Streptococcus to human amniotic fluid.

  PloS one 20100101

• Abundant oligonucleotides common to most bacteria.

  PloS one 20100101

• Comparative genomics of metabolic networks of free-living and parasitic eukaryotes.

  BMC genomics 20100101

• Multiconstrained gene clustering based on generalized projections.

  BMC bioinformatics 20100101

• Specificity and functionality of microRNA inhibitors.

  Silence 20100101

• A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death.

  ASN neuro 20100101

• Empirical evaluation of oligonucleotide probe selection for DNA microarrays.

  PloS one 20100101

• The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.

  Arthritis research & therapy 20100101

• Platelet function and Isoprostane biology. Should isoprostanes be the newest member of the orphan-ligand family?

  Journal of biomedical science 20100101

• Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity.

  PloS one 20100101

• The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA?

  Biology direct 20100101

• PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia.

  PloS one 20100101

• Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels.

  BMC genomics 20100101

• Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths.

  BMC genomics 20100101

• Biology-driven cancer drug development: back to the future.

  BMC biology 20100101

• Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals.

  Antiviral therapy 20100101

• Soluble amyloid-beta, effect on cerebral arteriolar regulation and vascular cells.

  Molecular neurodegeneration 20100101

• Natural occurrence of 2',5'-linked heteronucleotides in marine sponges.

  Marine drugs 20100101

• Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages.

  Mediators of inflammation 20100101

• Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior.

  Molecular pain 20100101

• Genetic polymorphisms of MDM2 and TP53 genes are associated with risk of nasopharyngeal carcinoma in a Chinese population.

  BMC cancer 20100101

• Properties and identification of antibiotic drug targets.

  BMC bioinformatics 20100101

• Hyperuricaemia and the metabolic syndrome in type 2 DM.

  Diabetology & metabolic syndrome 20100101

• Primary metabolism in Lactobacillus sakei food isolates by proteomic analysis.

  BMC microbiology 20100101

• Comparison of Metabolic Risk Factors in Urolithiasis Patients according to Family History.

  Korean journal of urology 20100101

• Adenine oxidation by pyrite-generated hydroxyl radicals.

  Geochemical transactions 20100101

• Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortus.

  BMC genomics 20100101

• Risks vs benefits of glatiramer acetate: a changing perspective as new therapies emerge for multiple sclerosis.

  Therapeutics and clinical risk management 20100101

• The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound.

  PloS one 20100101

• Pemetrexed plus cisplatin/carboplatin in previously treated locally advanced or metastatic non-small cell lung cancer patients.

  Journal of experimental & clinical cancer research : CR 20100101

• Challenges in the frontline treatment of patients with chronic lymphocytic leukemia.

  Current hematologic malignancy reports 20100101

• Delayed presentation of severe combined immunodeficiency due to prolonged maternal T cell engraftment.

  Annals of Saudi medicine 20100101

• Fludarabine-induced bradycardia in a patient with refractory leukemia.

  Annals of Saudi medicine 20100101

• Large scale analysis of positional effects of single-base mismatches on microarray gene expression data.

  BioData mining 20100101

• Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution.

  Biology direct 20100101

• Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes.

  PloS one 20100101

• Changes in Adenylate Nucleotides Concentration and Na, K-ATPase Activities in Erythrocytes of Horses in Function of Breed and Sex.

  Veterinary medicine international 20100101

• Transcript profiling of common bean (Phaseolus vulgaris L.) using the GeneChip Soybean Genome Array: optimizing analysis by masking biased probes.

  BMC plant biology 20100101

• Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser.

  BMC genomics 20100101

• Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response.

  BMC genomics 20100101

• Nucleosome rotational setting is associated with transcriptional regulation in promoters of tissue-specific human genes.

  Genome biology 20100101

• Massively parallel pyrosequencing-based transcriptome analyses of small brown planthopper (Laodelphax striatellus), a vector insect transmitting rice stripe virus (RSV).

  BMC genomics 20100101

• Clinical experience in T cell deficient patients.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101

• An overview of Cdk1-controlled targets and processes.

  Cell division 20100101

• Expression for caffeine biosynthesis and related enzymes in Camellia sinensis.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101

• Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data.

  BMC bioinformatics 20100101

• Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis.

  BMC systems biology 20100101

• GC3 biology in corn, rice, sorghum and other grasses.

  BMC genomics 20100101

• Factors affecting the long-term response to tacrolimus in renal transplant patients: pharmacokinetic and pharmacogenetic approach.

  International journal of medical sciences 20100101

• Biosynthesis and molecular genetics of polyketides in marine dinoflagellates.

  Marine drugs 20100101

• [The clinical diagnostic value of a study of the activity of enzymes of the guanyl branch of purine metabolism in patients with ankylosing spondyloarthritis].

  Terapevticheskii arkhiv 20100101

• Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells.

  PloS one 20100101

• Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia.

  Molecular cancer 20100101

• Inhibitors of the Purine Salvage Pathway: A Valuable Approach for Antiprotozoal Chemotherapy?

  Current medicinal chemistry 20100101

• Glucose sensing in the pancreatic beta cell: a computational systems analysis.

  Theoretical biology & medical modelling 20100101

• Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder.

  BMC urology 20100101

• Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.

  PloS one 20100101

• Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.

  PloS one 20100101

• MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia.

  Molecular cancer 20100101

• Cartography of methicillin-resistant S. aureus transcripts: detection, orientation and temporal expression during growth phase and stress conditions.

  PloS one 20100101

• Comparative Global Gene Expression Profiles of Wild-Type Yersinia pestis CO92 and Its Braun Lipoprotein Mutant at Flea and Human Body Temperatures.

  Comparative and functional genomics 20100101

• Association analysis of retinoic acid receptor beta (RARbeta) gene with high myopia in Chinese subjects.

  Molecular vision 20100101

• Do anticodons of misacylated tRNAs preferentially mismatch codons coding for the misloaded amino acid?

  BMC molecular biology 20100101

• Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation.

  BMC microbiology 20100101

• A framework for classification of prokaryotic protein kinases.

  PloS one 20100101

• The role of transposable elements in the evolution of non-mammalian vertebrates and invertebrates.

  Genome biology 20100101

• Proteomic analysis of the fish pathogen Flavobacterium columnare.

  Proteome science 20100101

• Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor.

  BMC structural biology 20100101

• Global transcriptional analysis of Bacillus licheniformis reveals an overlap between heat shock and iron limitation stimulon.

  Journal of molecular microbiology and biotechnology 20100101

• The Waddlia genome: a window into chlamydial biology.

  PloS one 20100101

• Native aggregation as a cause of origin of temporary cellular structures needed for all forms of cellular activity, signaling and transformations.

  Theoretical biology & medical modelling 20100101

• A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization.

  BMC bioinformatics 20100101

• Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studies.

  BMC genomics 20100101

• Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphatase.

  PloS one 20100101

• Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.

  PloS one 20100101

• [Effect utilize of food biologically active additive on base the lipid marine hydrobions under experimental cardiovascular pathology rats].

  Voprosy pitaniia 20100101

• Synthesis of some novel hydrazono acyclic nucleoside analogues.

  Beilstein journal of organic chemistry 20100101

• Innate immune recognition and activation during HIV infection.

  Retrovirology 20100101

• Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti.

  BMC microbiology 20100101

• De novo characterization of a whitefly transcriptome and analysis of its gene expression during development.

  BMC genomics 20100101

• Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.

  PloS one 20100101

• Deletion of P2X2 and P2X3 receptor subunits does not alter motility of the mouse colon.

  Frontiers in neuroscience 20100101

• Radiolabeled nucleoside analogues for PET imaging of HSV1-tk gene expression.

  Current topics in medicinal chemistry 20100101

• Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia.

  PloS one 20100101

• Inborn errors of energy metabolism associated with myopathies.

  Journal of biomedicine & biotechnology 20100101

• Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo.

  Journal of experimental & clinical cancer research : CR 20100101

• Management of ANCA-associated vasculitis: Current trends and future prospects.

  Therapeutics and clinical risk management 20100101

• Structural basis of gate-DNA breakage and resealing by type II topoisomerases.

  PloS one 20100101

• Patterns of nucleotides that flank substitutions in human orthologous genes.

  BMC genomics 20100101

• Synergistic properties of methylxanthine with cadmium and mercury on dermatophytes.

  Journal of global infectious diseases 20100101

• Combining next-generation sequencing strategies for rapid molecular resource development from an invasive aphid species, Aphis glycines.

  PloS one 20100101

• Different integration site structures between L1 protein-mediated retrotransposition in cis and retrotransposition in trans.

  Mobile DNA 20100101

• First-line treatment of chronic lymphocytic leukemia: role of alemtuzumab.

  OncoTargets and therapy 20100101

• A single sequence context cannot satisfy all non-AUG initiator codons in yeast.

  BMC microbiology 20100101

• Features of recent codon evolution: a comparative polymorphism-fixation study.

  Journal of biomedicine & biotechnology 20100101

• Mining non-model genomic libraries for microsatellites: BAC versus EST libraries and the generation of allelic richness.

  BMC genomics 20100101

• A metabolic model of human erythrocytes: practical application of the E-Cell Simulation Environment.

  Journal of biomedicine & biotechnology 20100101

• Ribavirin for Crimean-Congo hemorrhagic fever: systematic review and meta-analysis.

  BMC infectious diseases 20100101

• Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.

  Journal of oncology 20100101

• Predicting functional associations from metabolism using bi-partite network algorithms.

  BMC systems biology 20100101

• Use of clofarabine for acute childhood leukemia.

  Biologics : targets & therapy 20100101

• 'Lantern-Shaped' Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt(2){HN=C(Bu)O}(4)L(2)](NO(3))(2).

  Bioinorganic chemistry and applications 20100101

• Molecular Architectures Derived from Metal Ions and the Flexible 3,3'-Bipyridine Ligand: Unexpected Dimer with Hg(II).

  Bioinorganic chemistry and applications 20100101

• Synthesis and Characterization of Novel Ruthenium(III) Complexes with Histamine.

  Bioinorganic chemistry and applications 20100101

• Identification and characterization of full-length cDNAs in channel catfish (Ictalurus punctatus) and blue catfish (Ictalurus furcatus).

  PloS one 20100101

• High serum uric acid increases the risk for nonalcoholic Fatty liver disease: a prospective observational study.

  PloS one 20100101

• Comparison of koala LPCoLN and human strains of Chlamydia pneumoniae highlights extended genetic diversity in the species.

  BMC genomics 20100101

• Over-expression of adenosine deaminase in mouse podocytes does not reverse puromycin aminonucleoside resistance.

  BMC nephrology 20100101

• Two origins for the gene encoding alpha-isopropylmalate synthase in fungi.

  PloS one 20100101

• Characterization of a Clp protease gene regulator and the reaeration response in Mycobacterium tuberculosis.

  PloS one 20100101

• Exercise-induced changes in renal URAT1 activity and expression in rats.

  Renal failure 20100101

• Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models.

  Molecular systems biology 20100101

• Differential gene expression profile of retinoblastoma compared to normal retina.

  Molecular vision 20100101

• Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling.

  Genome medicine 20100101

• What is a microsatellite: a computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats.

  Genome biology and evolution 20100101

• Microarray analysis of response of Salmonella during infection of HLA-B27- transfected human macrophage-like U937 cells.

  BMC genomics 20100101

• The effect of stereochemistry on sodium ion complexation in nucleoside-metallacarborane conjugates.

  Bioinorganic chemistry and applications 20100101

• Archaea signal recognition particle shows the way.

  Archaea (Vancouver, B.C.) 20100101

• Extracting the abstraction pyramid from complex networks.

  BMC bioinformatics 20100101

• R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair.

  Molecular cancer 20100101

• Biochemical and anatomical substrates of depression and sickness behavior.

  The Israel journal of psychiatry and related sciences 20100101

• Identification of targets and new developments in the treatment of multiple sclerosis--focus on cladribine.

  Drug design, development and therapy 20100101

• The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants.

  PloS one 20100101

• The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats.

  Respiratory research 20100101

• Pathophysiological roles for purines: adenosine, caffeine and urate.

  Progress in brain research 20100101

• Ranked retrieval of Computational Biology models.

  BMC bioinformatics 20100101

• Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes.

  PloS one 20100101

• The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.

  PloS one 20100101

• Acute, multiple-dose dermal and genetic toxicity of Nu-3: a novel antimicrobial agent.

  Journal of biomedicine & biotechnology 20100101

• Exercise stress testing in children with metabolic or neuromuscular disorders.

  International journal of pediatrics 20100101

• Homologous illegitimate random integration of foreign DNA into the X chromosome of a transgenic mouse line.

  BMC molecular biology 20100101

• Neurotoxic alkaloids: saxitoxin and its analogs.

  Marine drugs 20100101

• Forever young: mechanisms of natural anoxia tolerance and potential links to longevity.

  Oxidative medicine and cellular longevity 20100101

• In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells.

  BMC cancer 20100101

• Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus.

  BMC evolutionary biology 20100101

• DNA mismatch repair in eukaryotes and bacteria.

  Journal of nucleic acids 20100101

• DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences.

  Journal of nucleic acids 20100101

• Structural determinants of photoreactivity of triplex forming oligonucleotides conjugated to psoralens.

  Journal of nucleic acids 20100101

• Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.

  Journal of translational medicine 20100101

• Systems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensis.

  BMC systems biology 20100101

• Digital expression profiling of novel diatom transcripts provides insight into their biological functions.

  Genome biology 20100101

• Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV.

  Journal of nucleic acids 20100101

• Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta.

  Journal of nucleic acids 20100101

• The relation of coffee consumption to serum uric Acid in Japanese men and women aged 49-76 years.

  Journal of nutrition and metabolism 20100101

• Structural properties of g,t-parallel duplexes.

  Journal of nucleic acids 20100101

• Amino acid composition in endothermic vertebrates is biased in the same direction as in thermophilic prokaryotes.

  BMC evolutionary biology 20100101

• Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis.

  BMC systems biology 20100101

• A transcriptomic approach highlights induction of secondary metabolism in citrus fruit in response to Penicillium digitatum infection.

  BMC plant biology 20100101

• Cross-reactions between engineered xylose and galactose pathways in recombinant Saccharomyces cerevisiae.

  Biotechnology for biofuels 20100101

• SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA.

  Journal of nucleic acids 20100101

• Cellular responses to Cisplatin-induced DNA damage.

  Journal of nucleic acids 20100101

• Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing.

  PloS one 20100101

• Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics.

  Genome medicine 20100101

• Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

  Molecular systems biology 20100101

• HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology.

  Molecular systems biology 20100101

• [Synthesis and biological properties of pyrimidine 4'-fluoro nucleosides and 4'-fluoro uridine 5'-O-triphospate].

  Bioorganicheskaia khimiia 20100101

• Topical ganciclovir in the treatment of acute herpetic keratitis.

  Clinical ophthalmology (Auckland, N.Z.) 20100101

• A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues.

  PloS one 20100101

• Using evolutionary conserved modules in gene networks as a strategy to leverage high throughput gene expression queries.

  PloS one 20100101

• Preservation of differentiation and clonogenic potential of human hematopoietic stem and progenitor cells during lyophilization and ambient storage.

  PloS one 20100101

• GOPred: GO molecular function prediction by combined classifiers.

  PloS one 20100101

• Analyzing the regulation of metabolic pathways in human breast cancer.

  BMC medical genomics 20100101

• Brain architecture of the largest living land arthropod, the Giant Robber Crab Birgus latro (Crustacea, Anomura, Coenobitidae): evidence for a prominent central olfactory pathway?

  Frontiers in zoology 20100101

• Improvement in medication education in a pediatric subspecialty practice.

  Pediatric rheumatology online journal 20100101

• FATS is a transcriptional target of p53 and associated with antitumor activity.

  Molecular cancer 20100101

• Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study.

  PloS one 20100101

• High-density expression of Ca2+-permeable ASIC1a channels in NG2 glia of rat hippocampus.

  PloS one 20100101

• CPP-ZFN: a potential DNA-targeting anti-malarial drug.

  Malaria journal 20100101

• Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers.

  Journal of biological regulators and homeostatic agents 20100101

• MetNetGE: interactive views of biological networks and ontologies.

  BMC bioinformatics 20100101

• Emerging oral treatments in multiple sclerosis - clinical utility of cladribine tablets.

  Therapeutics and clinical risk management 20100101

• Temsirolimus in the treatment of relapsed or refractory mantle cell lymphoma.

  OncoTargets and therapy 20100101

• Current and emerging therapies for the treatment of pancreatic cancer.

  OncoTargets and therapy 20100101

• A proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress.

  Proteome science 20100101

• ModuleOrganizer: detecting modules in families of transposable elements.

  BMC bioinformatics 20100101

• The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism.

  Journal of nucleic acids 20100101

• Understanding the physiology of Lactobacillus plantarum at zero growth.

  Molecular systems biology 20100101

• A phenomenological model for predicting melting temperatures of DNA sequences.

  PloS one 20100101

• Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks.

  BMC medical genomics 20100101

• PPARs in Rhythmic Metabolic Regulation and Implications in Health and Disease.

  PPAR research 20100101

• Elevated adenosine deaminase levels in celiac disease.

  Journal of clinical laboratory analysis 20100101

• Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types.

  BMC bioinformatics 20100101

• Coordination Reactions and Noncovalent Interactions of Polyamines with Nucleotides in Binary Systems and with Nucleotides and Copper(II) Ion in Ternary Systems.

  Bioinorganic chemistry and applications 20100101

• USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.

  PloS one 20100101

• Flow cytometry and polymerase chain reaction-based analyses of minimal residual disease in chronic lymphocytic leukemia.

  Advances in hematology 20100101

• [Clinico-pathogenetic significance of enzymes regulating nucleic metabolism in erythrocyte lysates and sera of patients with osteoarthrosis].

  Klinicheskaia meditsina 20100101

• Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics.

  BMC genomics 20100101

• SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer.

  BMC cancer 20100101

• Cloning and characterization of a novel alternatively spliced transcript of the human CHD7 putative helicase.

  BMC research notes 20100101

• E. coli 6S RNA: a universal transcriptional regulator within the centre of growth adaptation.

  RNA biology 20100101

• Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines.

  BMC bioinformatics 20100101

• Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant.

  Journal of nucleic acids 20100101

• Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization.

  Journal of nucleic acids 20100101

• Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe.

  Journal of nucleic acids 20100101

• Translesion synthesis polymerases in the prevention and promotion of carcinogenesis.

  Journal of nucleic acids 20100101

• Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies.

  Journal of nucleic acids 20100101

• Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence.

  BMC genomics 20100101

• T-RFPred: a nucleotide sequence size prediction tool for microbial community description based on terminal-restriction fragment length polymorphism chromatograms.

  BMC microbiology 20100101

• Mutational dynamics of murine angiogenin duplicates.

  BMC evolutionary biology 20100101

• Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling.

  BMC genomics 20100101

• Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia.

  BMC cancer 20100101

• Urine alkalization facilitates uric acid excretion.

  Nutrition journal 20100101

• Modeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data directed for maximization of analytical reliability.

  PloS one 20100101

• Quantitative analysis of cellular metabolic dissipative, self-organized structures.

  International journal of molecular sciences 20100101

• Potential short-term use of oral cladribine in treatment of relapsing-remitting multiple sclerosis.

  Neuropsychiatric disease and treatment 20100101

• Molecular mechanisms of persistence of mutualistic bacteria Photorhabdus in the entomopathogenic nematode host.

  PloS one 20100101

• Current and developing therapeutic agents in the treatment of Chagas disease.

  Drug design, development and therapy 20100101

• Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation.

  Molecular cytogenetics 20100101

• Gene duplications in prokaryotes can be associated with environmental adaptation.

  BMC genomics 20100101

• Antitumor activity against murine lymphoma L5178Y model of proteins from cacao (Theobroma cacao L.) seeds in relation with in vitro antioxidant activity.

  BMC complementary and alternative medicine 20100101

• A QSAR study on some series of anti-hepatitis B virus (HBV) agents.

  Bioinformation 20100101

• Bioreducible liposomes for gene delivery: from the formulation to the mechanism of action.

  PloS one 20100101

• Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine.

  Journal of nucleic acids 20100101

• Insights into the structures of DNA damaged by hydroxyl radical: crystal structures of DNA duplexes containing 5-formyluracil.

  Journal of nucleic acids 20100101

• The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1.

  Journal of hematology & oncology 20100101

• Evolutionary rates and gene dispensability associate with replication timing in the archaeon Sulfolobus islandicus.

  Genome biology and evolution 20100101

• Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data.

  BMC cancer 20100101

• Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia.

  Molecular cancer 20100101

• Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems.

  Journal of nucleic acids 20100101

• The effects of forodesine in murine and human multiple myeloma cells.

  Advances in hematology 20100101

• Developmental pharmacogenetics in pediatric rheumatology: utilizing a new paradigm to effectively treat patients with juvenile idiopathic arthritis with methotrexate.

  Human genomics and proteomics : HGP 20100101

• Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.

  Bioinformatics and biology insights 20100101

• Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis.

  Journal of nucleic acids 20100101

• Effects of mycophenolate mofetil on proliferation and mucin-5AC expression in human conjunctival goblet cells in vitro.

  Molecular vision 20100101

• Circadian signatures in rat liver: from gene expression to pathways.

  BMC bioinformatics 20100101

• Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.

  BMC bioinformatics 20100101

• Mapping transcription mechanisms from multimodal genomic data.

  BMC bioinformatics 20100101

• How does methotrexate suppress inflammation?

  Clinical and experimental rheumatology 20100101

• Global protein interactome exploration through mining genome-scale data in Arabidopsis thaliana.

  BMC genomics 20100101

• Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells.

  BMC cancer 20100101

• Effects of inosine on reperfusion injury after cardiopulmonary bypass.

  Journal of cardiothoracic surgery 20100101

• Evaluation of suitable reference genes for normalization of real-time reverse transcription PCR analysis in colon cancer.

  Journal of experimental & clinical cancer research : CR 20100101

• Modeling compositional dynamics based on GC and purine contents of protein-coding sequences.

  Biology direct 20100101

• Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma.

  PloS one 20100101

• A comparative analysis of gene-expression data of multiple cancer types.

  PloS one 20100101

• Proteome of the phytopathogen Xanthomonas citri subsp. citri: a global expression profile.

  Proteome science 20100101

• A genome-wide association scan on estrogen receptor-negative breast cancer.

  Breast cancer research : BCR 20100101

• Syzygium cumini extract decrease adenosine deaminase, 5'nucleotidase activities and oxidative damage in platelets of diabetic patients.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

• Impact of the Staphylococcus epidermidis LytSR two-component regulatory system on murein hydrolase activity, pyruvate utilization and global transcriptional profile.

  BMC microbiology 20100101

• DNA suspension arrays: silencing discrete artifacts for high-sensitivity applications.

  PloS one 20100101

• Proteomic analysis of the dysferlin protein complex unveils its importance for sarcolemmal maintenance and integrity.

  PloS one 20100101

• Insights into metazoan evolution from Alvinella pompejana cDNAs.

  BMC genomics 20100101

• Effects of site-directed mutagenesis of mglA on motility and swarming of Myxococcus xanthus.

  BMC microbiology 20100101

• Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis.

  PloS one 20100101

• Targeted metabolomics and mass spectrometry.

  Advances in protein chemistry and structural biology 20100101

• A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production.

  BMC genomics 20100101

• Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast.

  Molecular systems biology 20100101

• Factors influencing cerebral plasticity in the normal and injured brain.

  Frontiers in human neuroscience 20100101

• The diagnosis of inherited metabolic diseases by microarray gene expression profiling.

  Orphanet journal of rare diseases 20100101

• Molecular characterization of Borrelia persica, the agent of tick borne relapsing fever in Israel and the Palestinian Authority.

  PloS one 20100101

• Post-transcriptional control by bacteriophage T4: mRNA decay and inhibition of translation initiation.

  Virology journal 20100101

• Therapeutic activity of two xanthones in a xenograft murine model of human chronic lymphocytic leukemia.

  Journal of hematology & oncology 20100101

• The antagonism between MCT-1 and p53 affects the tumorigenic outcomes.

  Molecular cancer 20100101

• A garter snake transcriptome: pyrosequencing, de novo assembly, and sex-specific differences.

  BMC genomics 20100101

• Recent N-atom containing compounds from indo-pacific invertebrates.

  Marine drugs 20100101

• Comparative profiling of the transcriptional response to iron restriction in six serotypes of Actinobacillus pleuropneumoniae with different virulence potential.

  BMC genomics 20100101

• Synthesis of phenolics and flavonoids in ginger (Zingiber officinale Roscoe) and their effects on photosynthesis rate.

  International journal of molecular sciences 20100101

• Effect of oxidative damage due to excessive protein ingestion on pancreas function in mice.

  International journal of molecular sciences 20100101

• Nelarabine in the treatment of refractory T-cell malignancies.

  Clinical Medicine Insights. Oncology 20100101

• Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease.

  International journal of Alzheimer's disease 20100101

• Efficient gene targeting by homologous recombination in rat embryonic stem cells.

  PloS one 20100101

• Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase.

  PloS one 20100101

• Metabolic and transcriptomic responses of weaned pigs induced by different dietary amylose and amylopectin ratio.

  PloS one 20100101

• Evolution of interferon-based therapy for chronic hepatitis C.

  Hepatitis research and treatment 20100101

• Treatment of hepatitis C infections with interferon: a historical perspective.

  Hepatitis research and treatment 20100101

• Severe Relapsing Goodpasture's Disease Successfully Treated with Mycophenolate Mofetil.

  International journal of nephrology 20100101

• Recent advances in fragment-based QSAR and multi-dimensional QSAR methods.

  International journal of molecular sciences 20100101

• Effect of different light intensities on total phenolics and flavonoids synthesis and anti-oxidant activities in young ginger varieties (Zingiber officinale Roscoe).

  International journal of molecular sciences 20100101

• A comparative study of the inhibitory effects of purine nucleotides and carboxyatractylate on the uncoupling protein-3 and adenine nucleotide translocase.

  Acta biochimica Polonica 20100101

• Alpha-Tocopherol Modulates Transcriptional Activities that Affect Essential Biological Processes in Bovine Cells.

  Gene regulation and systems biology 20100101

• A genome alignment algorithm based on compression.

  BMC bioinformatics 20100101

• A proposal for identifying the low renal uric acid clearance phenotype.

  Arthritis research & therapy 20100101

• Physiological responses to folate overproduction in Lactobacillus plantarum WCFS1.

  Microbial cell factories 20100101

• Study of nephrotoxic potential of acetaminophen in birds.

  Toxicology international 20100101

• Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women.

  PloS one 20100101

• Direct injection of functional single-domain antibodies from E. coli into human cells.

  PloS one 20100101

• Vaccination and infection prevention in inflammatory bowel disease.

  F1000 medicine reports 20100101

• Distribution of short interstitial telomere motifs in two plant genomes: putative origin and function.

  BMC plant biology 20100101

• Evidences showing wide presence of small genomic aberrations in chronic lymphocytic leukemia.

  BMC research notes 20100101

• The colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information.

  BMC cancer 20100101

• Serum neutrophil gelatinase-B associated lipocalin (NGAL) levels in Down's syndrome patients.

  Immunity & ageing : I & A 20100101

• Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses.

  PloS one 20100101

• Rituximab for the treatment of patients with chronic lymphocytic leukemia.

  Cancer management and research 20100101

• Temsirolimus in the treatment of relapsed and/or refractory mantle cell lymphoma.

  Cancer management and research 20100101

• Targeting the OB-Folds of Replication Protein A with Small Molecules.

  Journal of nucleic acids 20100101

• Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis.

  Advances in pharmacological sciences 20100101

• An update in management of noncutaneous T-cell lymphomas.

  Advances in hematology 20100101

• Rift Valley fever virus(Bunyaviridae: Phlebovirus): an update on pathogenesis, molecular epidemiology, vectors, diagnostics and prevention.

  Veterinary research 20100101

• Transient expression of βC1 protein differentially regulates host genes related to stress response, chloroplast and mitochondrial functions.

  Virology journal 20100101

• Complete Mitochondrial Genome Sequence of Acrida cinerea (Acrididae: Orthoptera) and Comparative Analysis of Mitochondrial Genomes in Orthoptera.

  Comparative and functional genomics 20100101

• Analysis of KRAS Mutations of Exon 2 Codons 12 and 13 by SNaPshot Analysis in Comparison to Common DNA Sequencing.

  Gastroenterology research and practice 20100101

• Epidemiology of gout.

  Arthritis research & therapy 20100101

• Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.

  Journal of nucleic acids 20100101

• CoFactor: Folate Requirement for Optimization of 5-Fluouracil Activity in Anticancer Chemotherapy.

  Journal of oncology 20100101

• The biological and metabolic fates of endogenous DNA damage products.

  Journal of nucleic acids 20100101

• Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice.

  PloS one 20100101

• Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells.

  PloS one 20100101

• Formation and repair of tobacco carcinogen-derived bulky DNA adducts.

  Journal of nucleic acids 20100101

• Disease modifying agents for multiple sclerosis.

  The open neurology journal 20100101

• Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells.

  The open microbiology journal 20100101

• The spectrum of use of rituximab in chronic lymphocytic leukemia.

  OncoTargets and therapy 20100101

• Cancer chemotherapy: targeting folic acid synthesis.

  Cancer management and research 20100101

• Clinical and experimental advances in regeneration of spinal cord injury.

  Journal of tissue engineering 20100101

• Structure modeling of novel DNA glycosylase enzyme from oral pathogen Streptococcus sanguinis.

  Bioinformation 20100101

• Mapping of origin of replication in Themococcales.

  Bioinformation 20100101

• Epidemiology of pediatric urolithiasis.

  Indian journal of urology : IJU : journal of the Urological Society of India 20100101

• Nutritional aspect of nephrolithiasis.

  Indian journal of urology : IJU : journal of the Urological Society of India 20100101

• [Purine analgesia: experimental results and clinical perspectives].

  Anesteziologiia i reanimatologiia 20100101

• Application of new drugs in chronic lymphocytic leukemia.

  Mediterranean journal of hematology and infectious diseases 20100101

• Allogeneic hematopoietic cell transplantation in the treatment of chronic lymphocytic leukemia: why and when?

  Mediterranean journal of hematology and infectious diseases 20100101

• New treatments for myelodysplastic syndromes.

  Mediterranean journal of hematology and infectious diseases 20100101

• Allogeneic transplantation for chronic lymphocytic leukemia.

  Mediterranean journal of hematology and infectious diseases 20100101

• Biochemistry and occurrence of o-demethylation in plant metabolism.

  Frontiers in physiology 20100101

• Ammonia production, excretion, toxicity, and defense in fish: a review.

  Frontiers in physiology 20100101

• Update on the management of chronic eczema: new approaches and emerging treatment options.

  Clinical, cosmetic and investigational dermatology 20100101

• [Plant purine nucleotide cyclases].

  Postepy biochemii 20100101

• History, epidemiology and regional diversities of urolithiasis.

  Pediatric nephrology (Berlin, Germany) 20100101

• Genetic manipulation of francisella tularensis.

  Frontiers in microbiology 20100101

• Genotoxicity and mutagenicity of Echinodorus macrophyllus (chapéu-de-couro) extracts.

  Genetics and molecular biology 20100101

• Exploitation of host cell biology and evasion of immunity by francisella tularensis.

  Frontiers in microbiology 20100101

• The Role of the Francisella Tularensis Pathogenicity Island in Type VI Secretion, Intracellular Survival, and Modulation of Host Cell Signaling.

  Frontiers in microbiology 20100101

• Francisella tularensis metabolism and its relation to virulence.

  Frontiers in microbiology 20100101

• Use of a rabbit soft tissue chamber model to investigate campylobacter jejuni-host interactions.

  Frontiers in microbiology 20100101

• The francisella tularensis proteome and its recognition by antibodies.

  Frontiers in microbiology 20100101

• The francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation.

  Frontiers in microbiology 20100101

• Advances in the management of gout: critical appraisal of febuxostat in the control of hyperuricemia.

  International journal of nephrology and renovascular disease 20100101

• Role of tacrolimus combination therapy with mycophenolate mofetil in the prevention of organ rejection in kidney transplant patients.

  International journal of nephrology and renovascular disease 20100101

• New and improved strategies for the treatment of gout.

  International journal of nephrology and renovascular disease 20100101

• Chemical warfare agents.

  Journal of pharmacy & bioallied sciences 20100101

• Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses.

  Journal of pharmacy & bioallied sciences 20100101

• Bladder dysfunction in diabetes mellitus.

  Frontiers in pharmacology 20100101

• Cost effectiveness and quality of life considerations in the treatment of hepatitis C infection.

  ClinicoEconomics and outcomes research : CEOR 20100101

• Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders.

  International journal of proteomics 20100101

• Emerging therapies for treatment of multiple sclerosis.

  Journal of inflammation research 20100101

• Management of Pneumocystis Jirovecii pneumonia in HIV infected patients: current options, challenges and future directions.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Critical analysis of herbs acting on Mutravaha srotas.

  Ayu 20100101

• A clinical comparative study of the management of chronic renal failure with Punarnavadi compound.

  Ayu 20100101

• Various techniques for the evaluation of anti arthritic activity in animal models.

  Journal of advanced pharmaceutical technology & research 20100101

• Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL).

  Journal of blood medicine 20100101

• Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor.

  Journal of blood medicine 20100101

• Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project.

  Clinical pharmacology : advances and applications 20100101

• Prevention and management of antineoplastic therapy induced oral mucositis.

  National journal of maxillofacial surgery 20100101

• New Test System for Serine/Threonine Protein Kinase Inhibitors Screening: E. coli APHVIII/Pk25 design.

  Acta naturae 20100101

• Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor.

  Biochemical pharmacology 20091215

• Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

  The Journal of biological chemistry 20091211

• Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.

  The Journal of biological chemistry 20091211

• The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.

  Cell 20091211

• Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210

• Nucleobase lesions and strand breaks in dry DNA thin film selectively induced by monochromatic soft X-rays.

  The journal of physical chemistry. B 20091210

• Synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives from amino acids.

  Molecules (Basel, Switzerland) 20091209

• Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by human alkyladenine DNA glycosylase.

  Biochemistry 20091208

• NMR investigation of DNA primer-template models: guanine templates are less prone to strand slippage upon misincorporation.

  Biochemistry 20091208

• Reactions of Pd(II) with chelate-tethered 2,6-diaminopurine derivatives: N3-coordination and reaction of the purine system.

  Inorganic chemistry 20091207

• Solution structure of RCL, a novel 2'-deoxyribonucleoside 5'-monophosphate N-glycosidase.

  Journal of molecular biology 20091204

• Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors.

  Journal of molecular biology 20091204

• Effects of isovalerate on ruminal fermentation, urinary excretion of purine derivatives and digestibility in steers.

  Journal of animal physiology and animal nutrition 20091201

• Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study.

  Biopolymers 20091201

• Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

  Biochimica et biophysica acta 20091201

• Operons.

  Cellular and molecular life sciences : CMLS 20091201

• Molecular evolution of GYPC: evidence for recent structural innovation and positive selection in humans.

  Molecular biology and evolution 20091201

• Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei.

  Molecular and biochemical parasitology 20091201

• Opioid use affects antioxidant activity and purine metabolism: preliminary results.

  Human psychopharmacology 20091201

• Impaired up-regulation of polo-like kinase 2 in B-cell chronic lymphocytic leukaemia lymphocytes resistant to fludarabine and 2-chlorodeoxyadenosine: a potential marker of defective damage response.

  British journal of haematology 20091201

• New insights into the pathogenesis of adenosine deaminase-severe combined immunodeficiency and progress in gene therapy.

  Current opinion in allergy and clinical immunology 20091201

• Cystinuria: the South Indian experience.

  Urological research 20091201

• Identification of survival genes in human glioblastoma cells by small interfering RNA screening.

  Molecular pharmacology 20091201

• Dynamics of energy charge and adenine nucleotides during uncoupling of catabolism and anabolism in Penicillium ochrochloron.

  Mycological research 20091201

• Nanoparticles can cause DNA damage across a cellular barrier.

  Nature nanotechnology 20091201

• Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients.

  Journal of pharmacokinetics and pharmacodynamics 20091201

• In vivo assessment of mitochondrial toxicity of metacavir in Rhesus monkeys after three months of intravenous administration.

  Acta pharmacologica Sinica 20091201

• Pathological features of bone marrow transplantation-related toxicity in a mouse.

  Journal of veterinary science 20091201

• Graft-versus-leukemia effect of nonmyeloablative stem cell transplantation.

  The Korean journal of internal medicine 20091201

• A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.

  Nature medicine 20091201

• Cladribine inhibits a diltiazem-induced increase in red blood cell purine nucleotide concentrations in a zebrafish model.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20091201

• A mouse model of the human Fragile X syndrome I304N mutation.

  PLoS genetics 20091201

• Transcriptome and proteome exploration to model translation efficiency and protein stability in Lactococcus lactis.

  PLoS computational biology 20091201

• Preliminary crystallographic studies of purine nucleoside phosphorylase from the cariogenic pathogen Streptococcus mutans.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20091201

• Partition coefficients of some purine derivatives and its application to pharmacokinetics.

  Die Pharmazie 20091201

• Terpenyl-purines from the sea.

  Marine drugs 20091201

• Gouty tophi caused limited knee range of motion: a case report.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091201

• Role of Cordycepin and Adenosine on the Phenotypic Switch of Macrophages via Induced Anti-inflammatory Cytokines.

  Immune network 20091201

• Adult celiac disease and its malignant complications.

  Gut and liver 20091201

• Catabolism of hyaluronan: involvement of transition metals.

  Interdisciplinary toxicology 20091201

• 6-Benzyl-sulfanyl-9H-purine.

  Acta crystallographica. Section E, Structure reports online 20091201

• 6-(4-Fluoro-pheneth-yl)-7-imino-3-phenyl-2,3,6,7-tetra-hydro-1,3-thia-zolo[4,5-d]pyrimidine-2-thione.

  Acta crystallographica. Section E, Structure reports online 20091201

• Revisiting plus-strand DNA synthesis in retroviruses and long terminal repeat retrotransposons: dynamics of enzyme: substrate interactions.

  Viruses 20091201

• Determination of the biological activity and structure activity relationships of drugs based on the highly cytotoxic duocarmycins and CC-1065.

  Toxins 20091201

• Skew in the human caveolin 1 gene upstream purine complex homozygote haplotype compartment in multiple sclerosis.

  Journal of neuroimmunology 20091130

• Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids.

  Journal of the American Chemical Society 20091125

• The GTPase activity of Escherichia coli FtsZ determines the magnitude of the FtsZ polymer bundling by ZapA in vitro.

  Biochemistry 20091124

• Photophysics of xanthine: computational study of the radiationless decay mechanisms.

  Physical chemistry chemical physics : PCCP 20091121

• Design and antimicrobial action of purine analogues that bind Guanine riboswitches.

  ACS chemical biology 20091120

• Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach.

  Biochemistry 20091117

• Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice.

  British journal of cancer 20091117

• Diagnosing and treating chronic lymphocytic leukemia in 2009.

  Oncology (Williston Park, N.Y.) 20091115

• Uncoupling protein 1 inhibition by purine nucleotides is under the control of the endogenous ubiquinone redox state.

  The Biochemical journal 20091111

• Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA.

  Journal of the American Chemical Society 20091111

• Structure-specific recognition of Friedreich's ataxia (GAA)n repeats by benzoquinoquinoxaline derivatives.

  Chembiochem : a European journal of chemical biology 20091102

• Probing metal-ion purine interactions at DNA minor-groove sites.

  Inorganic chemistry 20091102

• Medical treatment of pediatric urolithiasis.

  Pediatric nephrology (Berlin, Germany) 20091101

• A 57-gene expression signature in B-cell chronic lymphocytic leukemia.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101

• Abnormal adenosine and dopamine receptor expression in lymphocytes of Lesch-Nyhan patients.

  Brain, behavior, and immunity 20091101

• Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis.

  Toxicology and applied pharmacology 20091101

• Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice.

  Diabetes 20091101

• Polymorphisms in arsenic metabolism genes, urinary arsenic methylation profile and cancer.

  Cancer causes & control : CCC 20091101

• A novel mutation in purine nucleoside phosphorylase in a child with normal uric acid levels.

  Clinical biochemistry 20091101

• Simultaneous quantification of 9-(beta-D-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography-tandem mass spectrometric assay.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101

• Proteome analysis of Lactobacillus rhamnosus GG using 2-D DIGE and mass spectrometry shows differential protein production in laboratory and industrial-type growth media.

  Journal of proteome research 20091101

• Purine nucleotides reduce superoxide production by nitric oxide synthase in a murine sepsis model.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091101

• NMR spectroscopy and kinetic studies of the quadruplex forming RNA r(UGGAGGU).

  Molecular bioSystems 20091101

• Polymorphisms in one-carbon metabolism pathway genes and risk for bladder cancer in a Tunisian population.

  Cancer genetics and cytogenetics 20091101

• Metabolomics applied to diabetes research: moving from information to knowledge.

  Diabetes 20091101

• Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity.

  Neoplasia (New York, N.Y.) 20091101

• Plasmodium falciparum: new molecular targets with potential for antimalarial drug development.

  Expert review of anti-infective therapy 20091101

• The malate synthase of Paracoccidioides brasiliensis Pb01 is required in the glyoxylate cycle and in the allantoin degradation pathway.

  Medical mycology 20091101

• The germ cell nuclear proteins hnRNP G-T and RBMY activate a testis-specific exon.

  PLoS genetics 20091101

• Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine.

  Journal of clinical biochemistry and nutrition 20091101

• Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity.

  Journal of clinical biochemistry and nutrition 20091101

• Modifiers of Prat, a de novo purine synthesis gene, in Drosophila melanogaster.

  Genome 20091101

• Review: what causes neurotoxicity after exposure to purine analogs?

  Clinical advances in hematology & oncology : H&O 20091101

• Stereoselective synthesis of 2-deoxy-2-fluoroarabinofuranosyl-alpha-1-phosphate and its application to the synthesis of 2'-deoxy-2'-fluoroarabinofuranosyl purine nucleosides by a chemo-enzymatic method.

  Nucleosides, nucleotides & nucleic acids 20091101

• The second-generation anticancer drug Nedaplatin: a theoretical investigation on the hydrolysis mechanism.

  The journal of physical chemistry. B 20091029

• Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors.

  Journal of molecular biology 20091023

• Characterisation of influenza A viruses with mutations in segment 5 packaging signals.

  Vaccine 20091023

• How I treat ADA deficiency.

  Blood 20091022

• Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.

  Blood 20091022

• The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.

  Biochemistry 20091020

• Brain purine metabolism and xanthine dehydrogenase/oxidase conversion in hyperammonemia are under control of NMDA receptors and nitric oxide.

  Brain research 20091019

• MAP kinase dependent cyclinE/cdk2 activity promotes DNA replication in early sea urchin embryos.

  Developmental biology 20091015

• Comparison of enzyme immobilisation methods for potentiometric phosphate biosensors.

  Biosensors & bioelectronics 20091015

• Genetics of human neural tube defects.

  Human molecular genetics 20091015

• Recent insights into the pathogenesis of hyperuricaemia and gout.

  Human molecular genetics 20091015

• Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

  Journal of the American Chemical Society 20091014

• Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.

  Biochemistry 20091013

• ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency.

  Blood 20091008

• Analysis of the interaction of the nucleotide base with myosin and the effect on substrate efficacy.

  Biophysical journal 20091007

• Methotrexate for maintenance of remission in Crohn's disease.

  The Cochrane database of systematic reviews 20091007

• A transthyretin-related protein is functionally expressed in Herbaspirillum seropedicae.

  Biochemical and biophysical research communications 20091002

• Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.

  The Journal of biological chemistry 20091002

• Comparison of bacterial pellets and microbial markers for the estimation of the microbial nitrogen and amino acids flows from single flow continuous culture fermenters fed diets containing two-stage olive cake.

  Journal of animal physiology and animal nutrition 20091001

• Co-expression of recombinant nucleoside phosphorylase from Escherichia coli and its application.

  Applied biochemistry and biotechnology 20091001

• Portal vein thrombosis in adult-onset Still's disease: a case report and literature review.

  Rheumatology international 20091001

• Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases.

  European journal of medicinal chemistry 20091001

• Different molecular mechanisms causing 9p21 deletions in acute lymphoblastic leukemia of childhood.

  Human genetics 20091001

• ITPase-deficient mice show growth retardation and die before weaning.

  Cell death and differentiation 20091001

• Clinical and experimental evidence of sympathetic neural dysfunction during inflammatory bowel disease.

  Clinical and experimental pharmacology & physiology 20091001

• An insight to the dynamics of conserved water molecular triad in IMPDH II (human): recognition of cofactor and substrate to catalytic Arg 322.

  Journal of biomolecular structure & dynamics 20091001

• DiProGB: the dinucleotide properties genome browser.

  Bioinformatics (Oxford, England) 20091001

• A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme.

  Molecular & cellular proteomics : MCP 20091001

• Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae.

  Genetics 20091001

• Alterations in tryptophan and purine metabolism in cocaine addiction: a metabolomic study.

  Psychopharmacology 20091001

• Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein.

  The FEBS journal 20091001

• Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding.

  The FEBS journal 20091001

• Valproic acid- and lithium-sensitivity in prs mutants of Saccharomyces cerevisiae.

  Biochemical Society transactions 20091001

• Feeding value of glycerol as a replacement for corn grain in rations fed to lactating dairy cows.

  Journal of dairy science 20091001

• Photocycloaddition of the T1 excited state of thioinosine to uridine and adenosine.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001

• Brugia malayi gene expression in response to the targeting of the Wolbachia endosymbiont by tetracycline treatment.

  PLoS neglected tropical diseases 20091001

• Historical aspects and milestones in the development of effective treatment for hairy cell leukemia.

  Leukemia & lymphoma 20091001

• Cladribine in the treatment of hairy cell leukemia: initial and subsequent results.

  Leukemia & lymphoma 20091001

• Combination therapies to improve the long-term outcome in hairy cell leukemia.

  Leukemia & lymphoma 20091001

• Long-term follow-up studies in hairy cell leukemia.

  Leukemia & lymphoma 20091001

• Approach to the patient after relapse of hairy cell leukemia.

  Leukemia & lymphoma 20091001

• Structure-based predictive models for allosteric hot spots.

  PLoS computational biology 20091001

• Recent progress in the treatment of acute lymphoblastic leukemia: clofarabine.

  Hematology/oncology clinics of North America 20091001

• Modern concepts in the treatment of chronic lymphocytic leukemia.

  Hematology (Amsterdam, Netherlands) 20091001

• Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20091001

• 1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway.

  PLoS genetics 20091001

• Helminth genomics: The implications for human health.

  PLoS neglected tropical diseases 20091001

• Infectious complications in patients with chronic lymphocytic leukemia: pathogenesis, spectrum of infection, and approaches to prophylaxis.

  Clinical lymphoma & myeloma 20091001

• Light directs zebrafish period2 expression via conserved D and E boxes.

  PLoS biology 20091001

• Progressive GAA.TTC repeat expansion in human cell lines.

  PLoS genetics 20091001

• Malaria vaccines: where next?

  PLoS pathogens 20091001

• Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians.

  Pharmacogenetics and genomics 20091001

• [Using adaptive mutagenesis system for identification of early genes encoding de novo purine biosynthesis in methylotrophic yeast Pichia methanolica MH4].

  Genetika 20091001

• Urate urolithiasis.

  Compendium (Yardley, PA) 20091001

• GeneWiz browser: An Interactive Tool for Visualizing Sequenced Chromosomes.

  Standards in genomic sciences 20090929

• Functional study of the P32T ITPA variant associated with drug sensitivity in humans.

  Journal of molecular biology 20090925

• Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine.

  The Journal of biological chemistry 20090925

• Punching holes in an enzyme.

  Chemistry & biology 20090925

• Ribocation transition state capture and rebound in human purine nucleoside phosphorylase.

  Chemistry & biology 20090925

• Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.

  Journal of molecular biology 20090918

• Electrochemical detection of natural DNA damage induced by ferritin/ascorbic acid/H2O2 system and amplification of DNA damage by endonuclease Fpg.

  Biosensors & bioelectronics 20090915

• Polar anionic metabolome analysis by nano-LC/MS with a metal chelating agent.

  Analytical chemistry 20090915

• Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable.

  The Journal of biological chemistry 20090904

• The genomes of the South American opossum (Monodelphis domestica) and platypus (Ornithorhynchus anatinus) encode a more complete purine catabolic pathway than placental mammals.

  Comparative biochemistry and physiology. Part D, Genomics & proteomics 20090903

• Polarizable empirical force field for nitrogen-containing heteroaromatic compounds based on the classical Drude oscillator.

  Journal of computational chemistry 20090901

• The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.

  Shock (Augusta, Ga.) 20090901

• Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.

  Toxicology and applied pharmacology 20090901

• Synthesis of a series of N6-substituted adenosines with activity against trypanosomatid parasites.

  European journal of medicinal chemistry 20090901

• Risk factors for severe infection in patients with hairy cell leukemia: a long-term study of 73 patients.

  European journal of haematology 20090901

• DNA interactions and photocatalytic strand cleavage by artificial nucleases based on water-soluble gold(III) porphyrins.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901

• Encapsulation of ruthenium nitrosylnitrate and DNA purines in nanostructured sol-gel silica matrices.

  Langmuir : the ACS journal of surfaces and colloids 20090901

• Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis.

  Neurochemistry international 20090901

• The role of transporters in the pharmacokinetics of orally administered drugs.

  Pharmaceutical research 20090901

• Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides.

  Biochemistry 20090901

• The transcriptionally active regions in the genome of Bacillus subtilis.

  Molecular microbiology 20090901

• Gout: is a purine-restricted diet still recommended?

  Journal of the American Dietetic Association 20090901

• Effect of pH and level of concentrate in the diet on the production of biohydrogenation intermediates in a dual-flow continuous culture.

  Journal of dairy science 20090901

• Acceleration of purine degradation by periodontal diseases.

  Journal of dental research 20090901

• Exploration of uncharted regions of the protein universe.

  PLoS biology 20090901

• Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.

  PLoS neglected tropical diseases 20090901

• Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing.

  PLoS pathogens 20090901

• Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

  Marine drugs 20090901

• [Effects of heroin and purine nucleotide compensation on neutral alpha-glucosidase in rat epididymides].

  Zhonghua nan ke xue = National journal of andrology 20090901

• Adenosine-based modulation of brain activity.

  Current neuropharmacology 20090901

• Release of adenosine and ATP during ischemia and epilepsy.

  Current neuropharmacology 20090901

• Tuning and fine-tuning of synapses with adenosine.

  Current neuropharmacology 20090901

• Adenosine A(2A) receptors in psychopharmacology: modulators of behavior, mood and cognition.

  Current neuropharmacology 20090901

• The role of adenosine in Alzheimer's disease.

  Current neuropharmacology 20090901

• Adenosine and stroke: maximizing the therapeutic potential of adenosine as a prophylactic and acute neuroprotectant.

  Current neuropharmacology 20090901

• Adenosine and the auditory system.

  Current neuropharmacology 20090901

• Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity.

  Current neuropharmacology 20090901

• Carcinoma and multiple lymphomas in one patient: establishing the diagnoses and analyzing risk factors.

  Journal of hematopathology 20090901

• Viroid replication: rolling-circles, enzymes and ribozymes.

  Viruses 20090901

• Guanine deaminase functions as dihydropterin deaminase in the biosynthesis of aurodrosopterin, a minor red eye pigment of Drosophila.

  The Journal of biological chemistry 20090828

• Synthesis and conformational analysis of locked carbocyclic analogues of 1,3-diazepinone riboside, a high-affinity cytidine deaminase inhibitor.

  The Journal of organic chemistry 20090821

• Pd(0)/Cu(I)-mediated direct arylation of 2'-deoxyadenosines: mechanistic role of Cu(I) and reactivity comparisons with related purine nucleosides.

  The Journal of organic chemistry 20090821

• Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM.

  Blood 20090820

• Templated synthesis of peptide nucleic acids via sequence-selective base-filling reactions.

  Journal of the American Chemical Society 20090819

• Adenosine: an endogenous modulator of innate immune system with therapeutic potential.

  European journal of pharmacology 20090815

• Identification of inhibitors of checkpoint kinase 1 through template screening.

  Journal of medicinal chemistry 20090813

• Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.

  Biochemistry 20090804

• A study of pyrimidine base damage in relation to oxidative stress and cancer.

  British journal of cancer 20090804

• Molecular modeling and dynamics studies of purine nucleoside phosphorylase from Bacteroides fragilis.

  Journal of molecular modeling 20090801

• Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils.

  Pflugers Archiv : European journal of physiology 20090801

• Substrate-dependent modulation of enzyme activity by allosteric effector antibodies.

  Biochimica et biophysica acta 20090801

• Cross-linking to an interrupted polypurine sequence with a platinum-modified triplex-forming oligonucleotide.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090801

• Determination of purine contents of alcoholic beverages using high performance liquid chromatography.

  Biomedical chromatography : BMC 20090801

• Hypoxanthine-guanine phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv: cloning, expression, and biochemical characterization.

  Protein expression and purification 20090801

• Theoretical studies on the interaction of modified pyrimidines and purines with purine riboswitch.

  Journal of molecular graphics & modelling 20090801

• Allantoin in human plasma, serum, and nasal-lining fluids as a biomarker of oxidative stress: avoiding artifacts and establishing real in vivo concentrations.

  Antioxidants & redox signaling 20090801

• Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence.

  The Prostate 20090801

• Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma.

  The Prostate 20090801

• The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major.

  Molecular and biochemical parasitology 20090801

• Effects of the purL gene expression level on the competitive nodulation ability of Sinorhizobium fredii.

  Current microbiology 20090801

• Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801

• Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: I. The role of arsenolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20090801

• Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.

  Toxicological sciences : an official journal of the Society of Toxicology 20090801

• The effect of endurance training on changes in purine metabolism: a longitudinal study of competitive long-distance runners.

  European journal of applied physiology 20090801

• Synthesis of 9-beta-d-arabinofuranosylguanine by combined use of two whole cell biocatalysts.

  Bioorganic & medicinal chemistry letters 20090801

• Cooperative regulation of ADE3 transcription by Gcn4p and Bas1p in Saccharomyces cerevisiae.

  Eukaryotic cell 20090801

• Oxygen and guanine-cytosine profiles in marine environments.

  Journal of molecular evolution 20090801

• Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090801

• Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I.

  Bioorganic & medicinal chemistry letters 20090801

• Role of ATP and related purines in inhibitory neurotransmission to the pig urinary bladder neck.

  British journal of pharmacology 20090801

• Azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in Crohn's disease: a meta-analysis.

  The American journal of gastroenterology 20090801

• Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.

  Development (Cambridge, England) 20090801

• Synthetic strategies toward carbocyclic purine-pyrimidine hybrid nucleosides.

  Bioorganic & medicinal chemistry 20090801

• Cladribine: not just another purine analogue?

  Expert opinion on investigational drugs 20090801

• Na-butyrate sustains energetic states of metabolism and t-PA productivity of CHO cells.

  Journal of bioscience and bioengineering 20090801

• Point: steady progress and current challenges in clinical islet transplantation.

  Diabetes care 20090801

• Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin.

  PLoS neglected tropical diseases 20090801

• Tissue effect on genetic control of transcript isoform variation.

  PLoS genetics 20090801

• [Separation of the up-regulated genes under nitrogen starvation from Phaeodactylum tricornutum by suppression subtractive hybridization technology].

  Yi chuan = Hereditas 20090801

• Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics.

  PLoS neglected tropical diseases 20090801

• Syzygium cumini inhibits adenosine deaminase activity and reduces glucose levels in hyperglycemic patients.

  Fundamental & clinical pharmacology 20090801

• Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide.

  Annals of the New York Academy of Sciences 20090801

• Selective cyclin-dependent kinase inhibitors discriminating between cell cycle and transcriptional kinases: future reality or utopia?

  Annals of the New York Academy of Sciences 20090801

• Is olomoucine, a weak CDK2 inhibitor, able to induce apoptosis in cancer cells?

  Annals of the New York Academy of Sciences 20090801

• ATP as modulator of carbacholine effect on contractility of rat myocardium in postnatal ontogeny.

  Bulletin of experimental biology and medicine 20090801

• A focus on natural variation for abiotic constraints response in the model species Arabidopsis thaliana.

  International journal of molecular sciences 20090801

• Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution.

  International journal of molecular sciences 20090801

• Myocardial energetics in left ventricular hypertrophy.

  Current cardiology reviews 20090801

• 4-Hydrazino-1-methyl-pyrazolo[3,4-d]pyrimidine.

  Acta crystallographica. Section E, Structure reports online 20090801

• Abacavir methanol 2.5-solvate.

  Acta crystallographica. Section E, Structure reports online 20090801

• Mechanism for attenuation of DNA binding by MarR family transcriptional regulators by small molecule ligands.

  Journal of molecular biology 20090731

• De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience.

  Blood 20090730

• Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells.

  Oncogene 20090730

• Escherichia coli DnaB helicase-DnaC protein complex: allosteric effects of the nucleotides on the nucleic acid binding and the kinetic mechanism of NTP hydrolysis. 3.

  Biochemistry 20090728

• Mechanism of NTP hydrolysis by the Escherichia coli primary replicative helicase DnaB protein. 2. Nucleotide and nucleic acid specificities.

  Biochemistry 20090728

• Probing anomalous structural features in polypurine tract-containing RNA-DNA hybrids with neomycin B.

  Biochemistry 20090728

• Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics.

  Journal of medicinal chemistry 20090723

• Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates.

  The EMBO journal 20090722

• Efficient charge transport in DNA diblock oligomers.

  Journal of the American Chemical Society 20090722

• A simple method for C-6 modification of guanine nucleosides.

  Organic & biomolecular chemistry 20090721

• MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition.

  British journal of cancer 20090721

• Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase.

  Bioorganic & medicinal chemistry 20090715

• PcrA helicase tightly couples ATP hydrolysis to unwinding double-stranded DNA, modulated by the initiator protein for plasmid replication, RepD.

  Biochemistry 20090714

• Antithetical effects of corticosterone and dibutyryl cAMP on adenosine deaminase in the gastrointestinal tract of chicken during postnatal development.

  Molecular and cellular biochemistry 20090701

• New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.

  Inflammatory bowel diseases 20090701

• Purification, properties, and kinetic studies of cytoplasmic malate dehydrogenase from Taenia solium cysticerci.

  Parasitology research 20090701

• A comparative study on urinary purine derivative excretion of yak (Bos grunniens), cattle (Bos taurus), and crossbred (Bos taurus x Bos grunniens) in the Qinghai-Tibetan plateau, China.

  Journal of animal science 20090701

• Diet, fluid, or supplements for secondary prevention of nephrolithiasis: a systematic review and meta-analysis of randomized trials.

  European urology 20090701

• Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients.

  Clinical biochemistry 20090701

• Development of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues.

  Cancer gene therapy 20090701

• Novel therapies for peripheral T-cell non-Hodgkin's lymphomas.

  Current opinion in hematology 20090701

• Treatment of fludarabine-refractory chronic lymphocytic leukemia.

  Cancer 20090701

• A functional analysis of the pyrimidine catabolic pathway in Arabidopsis.

  The New phytologist 20090701

• Immunosuppression in inflammatory bowel disease: traditional, biological or both?

  Current opinion in gastroenterology 20090701

• Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.

  Carcinogenesis 20090701

• Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy.

  Free radical research 20090701

• Antimalarial activity of thiosemicarbazones and purine derived nitriles.

  Bioorganic & medicinal chemistry letters 20090701

• Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer.

  Chemical reviews 20090701

• Regio- and enantioselective N-allylations of imidazole, benzimidazole, and purine heterocycles catalyzed by single-component metallacyclic iridium complexes.

  Journal of the American Chemical Society 20090701

• Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats.

  FEMS immunology and medical microbiology 20090701

• Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine.

  Antiviral research 20090701

• Adenosine A(2A) receptor mediates microglial process retraction.

  Nature neuroscience 20090701

• Bendamustine therapy in chronic lymphocytic leukemia.

  Expert opinion on pharmacotherapy 20090701

• Impact of ketone and amino on the inner shell of guanine.

  Journal of synchrotron radiation 20090701

• Hairy-cell leukemia with inaugural joint manifestations.

  Joint, bone, spine : revue du rhumatisme 20090701

• Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition.

  Cancer research 20090701

• The effects of arbuscular mycorrhizal fungi on direct and indirect defense metabolites of Plantago lanceolata L.

  Journal of chemical ecology 20090701

• Functional and structural alterations induced by copper in xanthine oxidase.

  Acta biochimica et biophysica Sinica 20090701

• Radiation metabolomics. 2. Dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice.

  Radiation research 20090701

• Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds.

  PLoS neglected tropical diseases 20090701

• Changes in plasma concentrations of hypoxanthine and uric acid before and after hemodialysis.

  Iranian journal of kidney diseases 20090701

• Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view.

  PLoS computational biology 20090701

• Comprehensive identification of Salmonella enterica serovar typhimurium genes required for infection of BALB/c mice.

  PLoS pathogens 20090701

• [Hairy cell leukemia: Part II: therapy with cladribine].

  Medizinische Monatsschrift fur Pharmazeuten 20090701

• 4-(1-Adamantylmeth-yl)-N-(2-chloro-9-isopropyl-9H-purin-6-yl)aniline.

  Acta crystallographica. Section E, Structure reports online 20090701

• New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids.

  Acta naturae 20090701

• Spinal mechanisms of antinociceptive action caused by guanosine in mice.

  European journal of pharmacology 20090624

• Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090624

• Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F).

  The Journal of biological chemistry 20090619

• Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3.

  The Journal of biological chemistry 20090619

• Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants.

  Biochemistry 20090616

• Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase.

  Biochemistry 20090616

• Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis.

  Archives of biochemistry and biophysics 20090615

• Identifying novel constrained elements by exploiting biased substitution patterns.

  Bioinformatics (Oxford, England) 20090615

• Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways.

  Genes & development 20090615

• Molecular adaptation in RNA complexes.

  Structure (London, England : 1993) 20090610

• Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase.

  The Journal of biological chemistry 20090605

• Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota.

  Journal of molecular biology 20090605

• Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus.

  Biochemistry 20090602

• Multiple endonucleases improve MALDI-MS signature digestion product detection of bacterial transfer RNAs.

  Analytical and bioanalytical chemistry 20090601

• Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches.

  Journal of molecular modeling 20090601

• The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release.

  Purinergic signalling 20090601

• Vinasse added to dried sugar beet pulp: preference rate, voluntary intake, and digestive utilization in sheep.

  Journal of animal science 20090601

• P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions.

  Naunyn-Schmiedeberg's archives of pharmacology 20090601

• The effect of ultraviolet radiation on the accumulation of medicinal compounds in plants.

  Fitoterapia 20090601

• Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.

  Biochimica et biophysica acta 20090601

• Molecular modeling, dynamics and docking studies of purine nucleoside phosphorylase from Streptococcus pyogenes.

  Biophysical chemistry 20090601

• Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.

  American journal of physiology. Renal physiology 20090601

• Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis.

  American journal of physiology. Lung cellular and molecular physiology 20090601

• Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab.

  Modern rheumatology 20090601

• FYX-051, a xanthine oxidoreductase inhibitor, induces nephropathy in rats, but not in monkeys.

  Toxicologic pathology 20090601

• Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis.

  British journal of haematology 20090601

• Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity.

  American journal of physiology. Renal physiology 20090601

• Effect of dietary purines on the pharmacokinetics of orally administered ribavirin.

  Journal of clinical pharmacology 20090601

• From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.

  Microbiology (Reading, England) 20090601

• Simultaneous electrochemical monitoring of metabolites related to the xanthine oxidase pathway using a grinded carbon electrode.

  Analytical chemistry 20090601

• Purine uptake in Plasmodium: transport versus metabolism.

  Trends in parasitology 20090601

• Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage.

  Molecular microbiology 20090601

• Induction of neurogenesis in rat bone marrow mesenchymal stem cells using purine structure-based compounds.

  Molecular bioSystems 20090601

• Clofarabine: a new treatment option for patients with acute myeloid leukemia.

  Expert opinion on pharmacotherapy 20090601

• [Prevalence and composition of urolithiasis in a pediatric Tunisian population].

  Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20090601

• Improvement of purine and pyrimidine antimetabolite-based anticancer treatment by selective suppression of mycoplasma-encoded catabolic enzymes.

  The Lancet. Oncology 20090601

• Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

  PLoS genetics 20090601

• Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees.

  PLoS pathogens 20090601

• FINDSITE: a threading-based approach to ligand homology modeling.

  PLoS computational biology 20090601

• Clofarabine as a novel nucleoside analogue approved to treat patients with haematological malignancies: mechanism of action and clinical activity.

  Mini reviews in medicinal chemistry 20090601

• Ribavirin acts via multiple pathways in inhibition of leukemic cell proliferation.

  Anticancer research 20090601

• Chronic lymphocytic leukemia: long-lasting remission with combination of cyclophosphamide, somatostatin, bromocriptine, retinoids, melatonin, and ACTH.

  Cancer biotherapy & radiopharmaceuticals 20090601

• Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using beta-CD as chiral selector.

  Electrophoresis 20090601

• Celebrating Achim Trebst's 80th birthday.

  Photosynthesis research 20090601

• Precambrian lunar volcanic protolife.

  International journal of molecular sciences 20090601

• Proteomic signature of reversine-treated murine fibroblasts by 2-D difference gel electrophoresis and MS: possible associations with cell signalling networks.

  Electrophoresis 20090601

• Pentostatin treatment combinations in chronic lymphocytic leukemia.

  Clinical advances in hematology & oncology : H&O 20090601

• Effect of fortifying concentrate supplement with fibrolytic enzymes on nutrient utilization, milk yield and composition in lactating goats.

  Animal science journal = Nihon chikusan Gakkaiho 20090601

• Adenosine and adenosine receptors: Newer therapeutic perspective.

  Indian journal of pharmacology 20090601

• Possibilities of alternative generation II biotests at Artemia.

  Interdisciplinary toxicology 20090601

• (1-Adamant-yl){4-[(2-chloro-9-isopropyl-9H-purin-6-yl)aminometh-yl]phen-yl}methanone trichloro-methane solvate.

  Acta crystallographica. Section E, Structure reports online 20090601

• The stimulatory effect of the organic sulfur supplement, mercaptopropane sulfonic acid on cellulolytic rumen microorganisms and microbial protein synthesis in cattle fed low sulfur roughages.

  Animal : an international journal of animal bioscience 20090601

• Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress.

  Chemical research in toxicology 20090518

• Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

  Chemical research in toxicology 20090518

• Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II.

  Bioorganic & medicinal chemistry letters 20090515

• Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I.

  Bioorganic & medicinal chemistry letters 20090515

• Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project.

  Blood 20090514

• Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics.

  Journal of medicinal chemistry 20090514

• Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry.

  Journal of medicinal chemistry 20090514

• Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon.

  Structure (London, England : 1993) 20090513

• Inhibition of erythrocyte phosphoribosyltransferases (APRT and HPRT) by Pb2+: a potential mechanism of lead toxicity.

  Toxicology 20090502

• Inhibition of Na+ transport in lung epithelial cells by respiratory syncytial virus infection.

  American journal of respiratory cell and molecular biology 20090501

• Reduced-intensity conditioning for severe aplasia using fludarabine and CY followed by infusion of ex vivo T-cell-depleted grafts leads to excellent engraftment and absence of GVHD.

  Bone marrow transplantation 20090501

• Purinergic receptor activation evokes neurotrophic factor neuropeptide Y release from neonatal mouse olfactory epithelial slices.

  Journal of neuroscience research 20090501

• Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20090501

• Damage recognition by UV damage endonuclease from Schizosaccharomyces pombe.

  DNA repair 20090501

• Behavioral response of human spermatozoa to a concentration jump of chemoattractants or intracellular cyclic nucleotides.

  Human reproduction (Oxford, England) 20090501

• The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.

  Antiviral research 20090501

• Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest.

  Veterinary pathology 20090501

• Increased xanthine oxidase in the skin of preeclamptic women.

  Reproductive sciences (Thousand Oaks, Calif.) 20090501

• Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization.

  Journal of neurochemistry 20090501

• Management of erectile function by penile purinergic p2 receptors in the diabetic rat.

  The Journal of urology 20090501

• Purinergic signalling in autonomic control.

  Trends in neurosciences 20090501

• Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine.

  Protein science : a publication of the Protein Society 20090501

• Liver and inflammatory bowel disease.

  Gastroenterologie clinique et biologique 20090501

• Autoimmune pancytopenia following combination chemotherapy for chronic lymphocytic leukaemia.

  Journal of clinical pathology 20090501

• Methotrexate treatment in pediatric Crohn disease patients intolerant or resistant to purine analogues.

  Journal of pediatric gastroenterology and nutrition 20090501

• Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts.

  PLoS genetics 20090501

• Widespread genomic signatures of natural selection in hominid evolution.

  PLoS genetics 20090501

• Additions, losses, and rearrangements on the evolutionary route from a reconstructed ancestor to the modern Saccharomyces cerevisiae genome.

  PLoS genetics 20090501

• [Malignant lymphomas].

  Gan to kagaku ryoho. Cancer & chemotherapy 20090501

• Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.

  PLoS biology 20090501

• Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies.

  PLoS pathogens 20090501

• Allopurinol, an inhibitor of uric acid synthesis--can it be used for the treatment of metabolic syndrome and related disorders?

  Drugs of today (Barcelona, Spain : 1998) 20090501

• Modulation of RNA metal binding by flanking bases: 15N NMR evaluation of GC, tandem GU, and tandem GA sites.

  Nucleosides, nucleotides & nucleic acids 20090501

• Synthesis and antiviral evaluation of 4'-C-azidomethyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20090501

• Synthesis and antiviral activity of purine 2',3'-dideoxy-2',3'-difluoro-D-arabinofuranosyl nucleosides.

  Nucleosides, nucleotides & nucleic acids 20090501

• Synthesis and anticancer evaluation of 4'-C-methyl-2'-fluoro arabino nucleosides.

  Nucleosides, nucleotides & nucleic acids 20090501

• International prognostic scoring system for Waldenstrom macroglobulinemia.

  Blood 20090430

• Loop-tryptophan human purine nucleoside phosphorylase reveals submillisecond protein dynamics.

  Biochemistry 20090428

• Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae.

  The Journal of biological chemistry 20090424

• Polypurine hairpins directed against the template strand of DNA knock down the expression of mammalian genes.

  The Journal of biological chemistry 20090424

• Effect of N7-protonated purine nucleosides on formation of C8 adducts in carcinogenic reactions of arylnitrenium ions with purine nucleosides: a quantum chemistry study.

  The journal of physical chemistry. B 20090423

• Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase.

  Biochemistry 20090421

• Methodological approaches in application of synthetic lethality screening towards anticancer therapy.

  British journal of cancer 20090421

• Synthesis of nucleoside Di- and triphosphates and dinucleoside polyphosphates with cycloSal-nucleotides.

  The Journal of organic chemistry 20090417

• Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.

  Blood 20090416

• A study of the ultrastructure of fragile-X-related proteins.

  The Biochemical journal 20090415

• A new synthesis and an antiviral assessment of the 4'-fluoro derivative of 4'-deoxy-5'-noraristeromycin.

  Bioorganic & medicinal chemistry 20090415

• The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells.

  Journal of immunology (Baltimore, Md. : 1950) 20090415

• Antimicrobial resistance induced by genetic changes.

  Journal of medicine and life 20090415

• Contribution of the reverse rate of the conformational step to polymerase beta fidelity.

  Biochemistry 20090414

• Biochemical characterization of the HpxO enzyme from Klebsiella pneumoniae, a novel FAD-dependent urate oxidase.

  Biochemistry 20090414

• Efficient procedure for isolating methylated catechins from green tea and effective simultaneous analysis of ten catechins, three purine alkaloids, and gallic acid in tea by high-performance liquid chromatography with diode array detection.

  Journal of chromatography. A 20090410

• Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisobenzofuran nucleoside analogs.

  Organic & biomolecular chemistry 20090407

• Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R).

  Investigational new drugs 20090401

• The effects of concentrate added to pineapple (Ananas comosus Linn. Mer.) waste silage in differing ratios to form complete diets, on digestion, excretion of urinary purine derivatives and blood metabolites in growing, male, Thai swamp buffaloes.

  Tropical animal health and production 20090401

• Inhibition of human poly(A)-specific ribonuclease (PARN) by purine nucleotides: kinetic analysis.

  Journal of enzyme inhibition and medicinal chemistry 20090401

• Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion.

  Clinical immunology (Orlando, Fla.) 20090401

• Fragmentation of isomeric intrastrand crosslink lesions of DNA in an ion-trap mass spectrometer.

  Journal of the American Society for Mass Spectrometry 20090401

• Extracellular guanosine and GTP promote expression of differentiation markers and induce S-phase cell-cycle arrest in human SH-SY5Y neuroblastoma cells.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090401

• Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.

  Biochimica et biophysica acta 20090401

• 2007 annual progress report synopsis of the Center for Structures of Membrane Proteins.

  Journal of structural and functional genomics 20090401

• Metabolism-blocked antifolates as potential anti-rheumatoid arthritis agents: 4-amino-4-deoxy-5,8,10-trideazapteroyl-d,l-4'-methyleneglutamic acid (CH-1504) and its analogs.

  Biochemical pharmacology 20090401

• The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines.

  Biochemical pharmacology 20090401

• Inhibiting the teratogenicity of the immunosuppressant leflunomide in mice by supplementation of exogenous uridine.

  Toxicological sciences : an official journal of the Society of Toxicology 20090401

• Differential proteomic analysis of lymphocytes treated with mycophenolic acid reveals caspase 3-induced cleavage of rho GDP dissociation inhibitor 2.

  Therapeutic drug monitoring 20090401

• Phenotypes of mutations in the 5'-UTR of a limiting transcription factor in Aspergillus nidulans can be accounted for by translational inhibition and leaky scanning.

  Genetics 20090401

• Transgenic expression of human equilibrative nucleoside transporter 1 in mouse neurons.

  Journal of neurochemistry 20090401

• The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro.

  Journal of neurochemistry 20090401

• Incorporation of an inducible nucleotide analog into DNA by DNA polymerases.

  Bioorganic & medicinal chemistry 20090401

• Immunophenotypic analysis of CD103+ B-lymphoproliferative disorders: hairy cell leukemia and its mimics.

  American journal of clinical pathology 20090401

• Inborn errors of purine and pyrimidine metabolism.

  Journal of inherited metabolic disease 20090401

• Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase.

  The FEBS journal 20090401

• Time-of-flight mass spectrometry (TOF-MS) exact mass database for benzodiazepine screening.

  Legal medicine (Tokyo, Japan) 20090401

• Regulation of Acanthamoeba castellanii alternative oxidase activity by mutual exclusion of purine nucleotides; ATP's inhibitory effect.

  Biochimica et biophysica acta 20090401

• Drug induction apoptosis assay as predictive value of chemotherapy response in patients with B-cell chronic lymphocytic leukemia.

  Leukemia & lymphoma 20090401

• Roles of purines in synaptic modulation evoked by hypercapnia in isolated spinal cord of neonatal rat in vitro.

  British journal of pharmacology 20090401

• A cell cycle timer for asymmetric spindle positioning.

  PLoS biology 20090401

• Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin.

  Journal of natural products 20090401

• Increased levels of 8-hydroxydeoxyguanosine and malondialdehyde and its relationship with antioxidant enzymes in saliva of periodontitis patients.

  European journal of dentistry 20090401

• Functional properties of the Ustilago maydis alternative oxidase under oxidative stress conditions.

  Mitochondrion 20090401

• [Genetic control of metabolism of mutagenic purine base analogs 6-hydroxylaminopurine and 2-amino-6-hydroxylaminopurine in yeast Saccharomyces cerevisiae].

  Genetika 20090401

• Etiology and management of tumor lysis syndrome in patients with chronic lymphocytic leukemia.

  Clinical advances in hematology & oncology : H&O 20090401

• Febuxostat: new drug. Hyperuricaemia: risk of gout attacks.

  Prescrire international 20090401

• The comparative study digestion and metabolism of nitrogen and purine derivatives in male, Thai, Swamp buffalo and Thai, Brahman cattle.

  Animal science journal = Nihon chikusan Gakkaiho 20090401

• Anaesthesia for renal transplantation: an update.

  Indian journal of anaesthesia 20090401

• Recovery of intravenously infused chromium EDTA and lithium sulphate in the urine of cattle and their use as markers to measure urine volume.

  Animal : an international journal of animal bioscience 20090401

• Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase: CRYSTAL STRUCTURES IN COMPLEX WITH XANTHINE AND LUMAZINE.

  The Journal of biological chemistry 20090327

• TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast.

  Molecular cell 20090327

• Thermus thermophilus strains active in purine nucleoside synthesis.

  Molecules (Basel, Switzerland) 20090324

• Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases.

  Molecules (Basel, Switzerland) 20090323

• Enantiodivergent synthesis of cyclohexenyl nucleosides.

  The Journal of organic chemistry 20090320

• Fluorescence emission properties of 8-aza analogues of caffeine, theophylline, and related N-alkyl xanthines.

  Bioorganic & medicinal chemistry 20090315

• New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine.

  Journal of medicinal chemistry 20090312

• Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).

  Biochemistry 20090310

• Resonance-enhanced multiphoton ionisation of purine.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20090309

• A novel polymorphic purine complex at the 1.5 kb upstream region of the human caveolin-1 gene and risk of Alzheimer's disease; extra-short alleles and accumulated allele homozygosity.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20090305

• Quenching of the fluorescence of aromatic pterins by deoxynucleotides.

  The journal of physical chemistry. A 20090305

• Conformational equilibria of bulged sites in duplex DNA studied by EPR spectroscopy.

  The journal of physical chemistry. B 20090305

• Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver.

  Physiological genomics 20090303

• Synthesis and pharmacological characterization of [(125)I]MRS1898, a high-affinity, selective radioligand for the rat A(3) adenosine receptor.

  Purinergic signalling 20090301

• Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases).

  Purinergic signalling 20090301

• Development of selective agonists and antagonists of P2Y receptors.

  Purinergic signalling 20090301

• Preface: special issue on medicinal chemistry of purines.

  Purinergic signalling 20090301

• Non-hemic autoimmunity in CLL.

  Leukemia research 20090301

• Treatment of B-cell chronic lymphocytic leukemia with nonchemotherapeutic agents: experience with single-agent and combination therapy.

  Leukemia 20090301

• Influence of different levels of concentrate and ruminally undegraded protein on digestive variables in beef heifers.

  Journal of animal science 20090301

• Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides.

  Molecular pharmacology 20090301

• Long-term follow-up of interferon-alpha induction and low-dose maintenance therapy in hairy cell leukemia.

  European journal of haematology 20090301

• Proteomic analysis of human macrophages exposed to hypochlorite-oxidized low-density lipoprotein.

  Biochimica et biophysica acta 20090301

• Biochemical characterization and homology modeling of a purine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus: insights into mechanisms of protein stabilization.

  Archives of biochemistry and biophysics 20090301

• Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands.

  Journal of inorganic biochemistry 20090301

• Allantoate amidohydrolase transcript expression is independent of drought tolerance in soybean.

  Journal of experimental botany 20090301

• Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.

  Toxicology in vitro : an international journal published in association with BIBRA 20090301

• Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major.

  Molecular microbiology 20090301

• Recent improvements in the development of A(2B) adenosine receptor agonists.

  Purinergic signalling 20090301

• Hepatosplenic T-cell lymphomas and therapy with TNF-alpha-blocking biologics: a risk for psoriasis patients?

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090301

• Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains.

  ChemMedChem 20090301

• Phylogenetic analysis and molecular evolution of guanine deaminases: from guanine to dendrites.

  Journal of molecular evolution 20090301

• Purinergic signaling in special senses.

  Trends in neurosciences 20090301

• Technical note: A new high-performance liquid chromatography purine assay for quantifying microbial flow.

  Journal of dairy science 20090301

• Characterization of nucleobase transport by mouse Sertoli cell line TM4.

  Biological & pharmaceutical bulletin 20090301

• Prolonged myelosuppression with clofarabine in the treatment of patients with relapsed or refractory, aggressive non-Hodgkin lymphoma.

  Leukemia & lymphoma 20090301

• T-cell prolymphocytic leukemia.

  Expert review of anticancer therapy 20090301

• Molecular and biological aspects of antimalarial resistance in Plasmodium falciparum and Plasmodium vivax.

  Current drug targets 20090301

• O6-(benzotriazol-1-yl)inosine derivatives for C6 modification of purine nucleosides.

  Current protocols in nucleic acid chemistry 20090301

• Stereoselective approach to the Z-isomers of methylenecyclopropane analogues of nucleosides: a new synthesis of antiviral synguanol.

  Nucleosides, nucleotides & nucleic acids 20090301

• Purine nucleotide catabolism in rat liver. Certain preliminary aspects of uricase reaction.

  Nucleosides, nucleotides & nucleic acids 20090301

• Fludarabine-based combination therapies for Waldenström's macroglobulinemia.

  Clinical lymphoma & myeloma 20090301

• Regulation of pyrimidine formation in Pseudomonas lundensis.

  Canadian journal of microbiology 20090301

• Role of metal oxides in chemical evolution: interaction of ribose nucleotides with alumina.

  Astrobiology 20090301

• [Clinical analysis of 15 patients with Waldenstrom macroglobulinemia].

  Zhonghua nei ke za zhi 20090301

• Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice.

  Aging 20090301

• Synthesis of labeled BCX-4208, a potent inhibitor of purine nucleoside phosphorylase.

  Drug testing and analysis 20090301

• Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.

  Journal of medicinal chemistry 20090226

• Measurement of oxidative DNA damage induced by mainstream cigarette smoke in cultured NCI-H292 human pulmonary carcinoma cells.

  Mutation research 20090219

• Reaction of hydrated electrons with guanine derivatives: tautomerism of intermediate species.

  The journal of physical chemistry. B 20090219

• Theoretical analysis on the transition state of the anticancer drug trans-[PtCl2(isopropylamine)2] and its cis isomer binding to DNA purine bases.

  The journal of physical chemistry. B 20090219

• Synthesis and antimicrobial evaluation of some new substituted purine derivatives.

  Bioorganic & medicinal chemistry 20090215

• 'Conditional Restraints': Restraining the Free Atoms in ARP/wARP.

  Structure (London, England : 1993) 20090213

• The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis.

  The Journal of biological chemistry 20090206

• Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.

  Biochemistry 20090203

• Growth pattern and partial proteome of Mycobacterium avium subsp. paratuberculosis during the stress response to hypoxia and nutrient starvation.

  Veterinary microbiology 20090202

• Ab initio study of the interactions between CO(2) and N-containing organic heterocycles.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20090202

• Debris clearance by microglia: an essential link between degeneration and regeneration.

  Brain : a journal of neurology 20090201

• Isolation and characterization of a novel adenosine deaminase inhibitor, IADA-7, from Bacillus sp. J-89.

  Journal of enzyme inhibition and medicinal chemistry 20090201

• Calorimetric study as a potential test for choosing treatment of B-cell chronic lymphocytic leukemia.

  Leukemia research 20090201

• The origin and evolution of modern metabolism.

  The international journal of biochemistry & cell biology 20090201

• Effects of forage:concentrate ratio and forage type on apparent digestibility, ruminal fermentation, and microbial growth in goats.

  Journal of animal science 20090201

• Rumen fermentation, microbial protein synthesis, and nutrient flow to the omasum in cattle offered corn silage, grass silage, or whole-crop wheat.

  Journal of animal science 20090201

• Two novel nucleobase/pentamidine transporters from Trypanosoma brucei.

  Molecular and biochemical parasitology 20090201

• Correlations of six related purine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.

  Clinical biochemistry 20090201

• Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.

  The British journal of dermatology 20090201

• Occurrence of theobromine synthase genes in purine alkaloid-free species of Camellia plants.

  Planta 20090201

• Pharmacological characterization of pannexin-1 currents expressed in mammalian cells.

  The Journal of pharmacology and experimental therapeutics 20090201

• Structural insights into the inhibited states of the Mer receptor tyrosine kinase.

  Journal of structural biology 20090201

• Successful treatment of refractory polymyositis with the immunosuppressant mizoribine: case report.

  Clinical rheumatology 20090201

• Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN.

  Bioorganic & medicinal chemistry letters 20090201

• Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.

  ChemMedChem 20090201

• Predicting gene expression level from relative codon usage bias: an application to Escherichia coli genome.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20090201

• Generation of an improved foamy virus vector by dissection of cis-acting sequences.

  The Journal of general virology 20090201

• The role of diet in the management of gout: a comparison of knowledge and attitudes to current evidence.

  Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 20090201

• Purines and oxypurines in myocardial ischemia.

  Saudi medical journal 20090201

• Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?

  Journal of anatomy 20090201

• A genome-scale metabolic reconstruction of Mycoplasma genitalium, iPS189.

  PLoS computational biology 20090201

• [Genetic diversity and origin of mitochondria DNA D-loop region of some Chinese indigenous cattle breeds].

  Yi chuan = Hereditas 20090201

• 2-(1-Adamant-yl)-1-{4-[(2-chloro-9-isopropyl-9H-purin-6-yl)amino-meth-yl]phen-yl}ethanone.

  Acta crystallographica. Section E, Structure reports online 20090201

• Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

  The New England journal of medicine 20090129

• Folate and colorectal cancer prevention.

  British journal of cancer 20090127

• A structural basis for the recognition of 2'-deoxyguanosine by the purine riboswitch.

  Journal of molecular biology 20090123

• Identification of bacteriophage N4 virion RNA polymerase-nucleic acid interactions in transcription complexes.

  The Journal of biological chemistry 20090123

• AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.

  FEBS letters 20090122

• Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one.

  Biochemistry 20090120

• Mutations in the Chinese hamster ovary cell GART gene of de novo purine synthesis.

  Gene 20090115

• 5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887.

  Archives of biochemistry and biophysics 20090115

• Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase.

  Bioorganic & medicinal chemistry 20090115

• Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase.

  Journal of the American Chemical Society 20090114

• Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha.

  Biochemistry 20090113

• Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing?

  Biochemistry 20090113

• Properties and reactivity of the adenosine radical generated by radiation-induced oxidation in aqueous solution.

  The journal of physical chemistry. B 20090108

• Insight into mechanism of formation of c8 adducts in carcinogenic reactions of arylnitrenium ions with purine nucleosides.

  The journal of physical chemistry. B 20090108

• A new role for cisplatin: probing ribosomal RNA structure.

  Chemical communications (Cambridge, England) 20090107

• Products and substrate/template usage of vaccinia virus DNA primase.

  Virology 20090105

• Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism.

  The Journal of biological chemistry 20090102

• Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library.

  Life sciences 20090102

• Adenosine receptor modulation: potential implications in veterinary medicine.

  Veterinary journal (London, England : 1997) 20090101

• Bovine endometrial legumain and TIMP-2 regulation in response to presence of a conceptus.

  Molecular reproduction and development 20090101

• Uric acid: A marker of increased cardiovascular risk.

  Atherosclerosis 20090101

• Characterisation of ATP analogues to cross-link and label P2X receptors.

  Neuropharmacology 20090101

• Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure.

  Journal of gastroenterology and hepatology 20090101

• Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society?

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090101

• Efficacy of the tubercidin antileishmania action associated with an inhibitor of the nucleoside transport.

  Parasitology research 20090101

• Neuroeffector Ca2+ transients for the direct measurement of purine release and indirect measurement of cotransmitters in rodents.

  Experimental physiology 20090101

• Purification and partial characterization of the xanthine-uric acid transporter (UapA) of Aspergillus nidulans.

  Protein expression and purification 20090101

• Double-stranded RNA specific to adenosine kinase and hypoxanthine-xanthine-guanine-phosphoribosyltransferase retards growth of Toxoplasma gondii.

  Parasitology research 20090101

• Temporal proteomic analysis of intestine developing necrotizing enterocolitis following enteral formula feeding to preterm pigs.

  Journal of proteome research 20090101

• Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells.

  British journal of haematology 20090101

• Purinergic signalling in the nervous system: an overview.

  Trends in neurosciences 20090101

• 2,6,9-Trisubstituted purine derivatives as protein A mimetics for the treatment of autoimmune diseases.

  Bioorganic & medicinal chemistry letters 20090101

• Anaerobic growth promotes synthesis of colonization factors encoded at the Vibrio pathogenicity island in Vibrio cholerae El Tor.

  Research in microbiology 20090101

• Pleuromutilin derivatives having a purine ring. Part 3: synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer.

  Bioorganic & medicinal chemistry letters 20090101

• Pleuromutilin derivatives having a purine ring. Part 2: influence of the central spacer on the antibacterial activity against Gram-positive pathogens.

  Bioorganic & medicinal chemistry letters 20090101

• The purine derivative PI-55 blocks cytokinin action via receptor inhibition.

  The FEBS journal 20090101

• Changing paradigms in diagnosis of inherited defects associated with urolithiasis.

  The Veterinary clinics of North America. Small animal practice 20090101

• Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors.

  Bioorganic & medicinal chemistry 20090101

• Membrane compartments and purinergic signalling: occurrence and function of P2X receptors in lung.

  The FEBS journal 20090101

• Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters.

  The FEBS journal 20090101

• Membrane compartments and purinergic signalling.

  The FEBS journal 20090101

• Mass spectrometry studies of the binding of the minor groove-directed alkylating agent alkamin to AT-tract oligonucleotides.

  Chemical research in toxicology 20090101

• Using profiles based on nucleotide hydrophobicity to define essential regions for splicing.

  International journal of biological sciences 20090101

• Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery.

  Parasitology 20090101

• Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment.

  PloS one 20090101

• The iron/heme regulated genes of Haemophilus influenzae: comparative transcriptional profiling as a tool to define the species core modulon.

  BMC genomics 20090101

• Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis.

  BMC evolutionary biology 20090101

• Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue.

  BMC chemical biology 20090101

• Molecular time-course and the metabolic basis of entry into dauer in Caenorhabditis elegans.

  PloS one 20090101

• Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.

  British journal of pharmacology 20090101

• Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair.

  BMC microbiology 20090101

• Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws--a promising method for speeding up the kinetic modelling of complex metabolic networks.

  The FEBS journal 20090101

• Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancer.

  Molecular cancer therapeutics 20090101

• Acute exercise and oxidative stress: a 30 year history.

  Dynamic medicine : DM 20090101

• Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii.

  PloS one 20090101

• Mitochondrial genome sequence and gene order of Sipunculus nudus give additional support for an inclusion of Sipuncula into Annelida.

  BMC genomics 20090101

• Chemical and molecular basis of the carcinogenicity of Aristolochia plants.

  Current opinion in drug discovery & development 20090101

• Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome.

  BMC genomics 20090101

• Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort.

  BMC gastroenterology 20090101

• Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception.

  PloS one 20090101

• Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines.

  PloS one 20090101

• Molecular identification of CTX-M and blaOXY/K1 beta-lactamase genes in Enterobacteriaceae by sequencing of universal M13-sequence tagged PCR-amplicons.

  BMC infectious diseases 20090101

• Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair.

  PloS one 20090101

• A novel function for fragile X mental retardation protein in translational activation.

  PLoS biology 20090101

• Improper excess light energy dissipation in Arabidopsis results in a metabolic reprogramming.

  BMC plant biology 20090101

• Preclinical support for combination therapy in the treatment of autoimmunity with atacicept.

  Toxicologic pathology 20090101

• One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation.

  Biology direct 20090101

• Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration.

  Arthritis research & therapy 20090101

• Nitrous oxide may not increase the risk of cancer recurrence after colorectal surgery: a follow-up of a randomized controlled trial.

  BMC anesthesiology 20090101

• mRNA stability and the unfolding of gene expression in the long-period yeast metabolic cycle.

  BMC systems biology 20090101

• Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites.

  BMC genomics 20090101

• MRI findings in 77 children with non-syndromic autistic disorder.

  PloS one 20090101

• Genome-scale analysis to the impact of gene deletion on the metabolism of E. coli: constraint-based simulation approach.

  BMC bioinformatics 20090101

• Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression.

  International journal of medical sciences 20090101

• Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.

  Genome biology 20090101

• Age and diet affect gene expression profile in canine skeletal muscle.

  PloS one 20090101

• Hematopoietic stem cell gene therapy for adenosine deaminase deficient-SCID.

  Immunologic research 20090101

• Regulating highly dynamic unstructured proteins and their coding mRNAs.

  Genome biology 20090101

• Comparison between the HCV IRES domain IV RNA structure and the Iron Responsive Element.

  Journal of negative results in biomedicine 20090101

• A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola.

  BMC systems biology 20090101

• Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs.

  BMC genomics 20090101

• A linear programming approach for estimating the structure of a sparse linear genetic network from transcript profiling data.

  Algorithms for molecular biology : AMB 20090101

• Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants.

  BMC biotechnology 20090101

• Unique signatures of natural background radiation on human Y chromosomes from Kerala, India.

  PloS one 20090101

• Circulating adhesion molecules and purine nucleotides during kidney allograft reperfusion.

  Transplantation proceedings 20090101

• Essential pathway identification: from in silico analysis to potential antifungal targets in Aspergillus fumigatus.

  Medical mycology 20090101

• Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine.

  PloS one 20090101

• Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.

  PloS one 20090101

• Fludarabine modulates immune response and extends in vivo survival of adoptively transferred CD8 T cells in patients with metastatic melanoma.

  PloS one 20090101

• Diverse protein regulations on PHA formation in Ralstonia eutropha on short chain organic acids.

  International journal of biological sciences 20090101

• Nutrition, anabolism, and the wound healing process: an overview.

  Eplasty 20090101

• The action of key factors in protein evolution at high temporal resolution.

  PloS one 20090101

• Aberrant epigenetic silencing is triggered by a transient reduction in gene expression.

  PloS one 20090101

• Reconstruction of metabolic pathways for the cattle genome.

  BMC systems biology 20090101

• Regulation of clock-controlled genes in mammals.

  PloS one 20090101

• Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy.

  BMC structural biology 20090101

• Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability.

  PloS one 20090101

• Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity.

  PloS one 20090101

• Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.

  PloS one 20090101

• High-throughput proteomics detection of novel splice isoforms in human platelets.

  PloS one 20090101

• Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae.

  BMC genomics 20090101

• Connecting extracellular metabolomic measurements to intracellular flux states in yeast.

  BMC systems biology 20090101

• Structural studies of PNP from Toxoplasma gondii.

  International journal of bioinformatics research and applications 20090101

• Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms.

  BioData mining 20090101

• Synthesis, anticancer and radioprotective activities of some new pyrazolo[3,4-d]pyrimidines containing amino acid moieties.

  Arzneimittel-Forschung 20090101

• The N-terminal domain of Escherichia coli RecA have multiple functions in promoting homologous recombination.

  Journal of biomedical science 20090101

• Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection.

  BMC cancer 20090101

• How close is the bench to the bedside? Metabolic profiling in cancer research.

  Genome medicine 20090101

• Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane.

  PloS one 20090101

• Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus.

  PloS one 20090101

• Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction.

  BMC systems biology 20090101

• Deciphering peculiar protein-protein interacting modules in Deinococcus radiodurans.

  Biology direct 20090101

• The p53HMM algorithm: using profile hidden markov models to detect p53-responsive genes.

  BMC bioinformatics 20090101

• Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Gene composer: database software for protein construct design, codon engineering, and gene synthesis.

  BMC biotechnology 20090101

• Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures.

  BMC microbiology 20090101

• Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture.

  AIDS research and therapy 20090101

• Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women.

  BMC cancer 20090101

• Detection of biochemical pathways by probabilistic matching of phyletic vectors.

  PloS one 20090101

• [In vitro biological activity of new platinum(II) and palladium(II) complex compounds].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20090101

• Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets.

  BMC genomics 20090101

• Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1.

  PloS one 20090101

• Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes.

  BMC systems biology 20090101

• Co-evolutionary networks of genes and cellular processes across fungal species.

  Genome biology 20090101

• A high speed detection platform based on surface-enhanced Raman scattering for monitoring antibiotic-induced chemical changes in bacteria cell wall.

  PloS one 20090101

• Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model.

  PloS one 20090101

• Resolution of tongue lesions caused by Leishmania infantum in a dog treated with the association miltefosine-allopurinol.

  Parasites & vectors 20090101

• Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression.

  Breast cancer research : BCR 20090101

• [Astrobiological investigations on board Russian space crafts].

  Tsitologiia 20090101

• Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection.

  Therapeutics and clinical risk management 20090101

• Fludarabine in the treatment of chronic lymphocytic leukemia: a review.

  Therapeutics and clinical risk management 20090101

• Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress.

  Vascular health and risk management 20090101

• Genome degradation in Brucella ovis corresponds with narrowing of its host range and tissue tropism.

  PloS one 20090101

• Characterizing structural transitions using localized free energy landscape analysis.

  PloS one 20090101

• Prediction of mono- and di-nucleotide-specific DNA-binding sites in proteins using neural networks.

  BMC structural biology 20090101

• The role of intrinsically unstructured proteins in neurodegenerative diseases.

  PloS one 20090101

• Effects of low-dose mizoribine pulse therapy in combination with methotrexate in rheumatoid arthritis patients with an insufficient response to methotrexate.

  Modern rheumatology 20090101

• Proteomic and network analysis characterize stage-specific metabolism in Trypanosoma cruzi.

  BMC systems biology 20090101

• Gene organization and sequence analyses of transfer RNA genes in Trypanosomatid parasites.

  BMC genomics 20090101

• Initiation codon mutation in betaB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract.

  Molecular vision 20090101

• Insights into the evolution of sialic acid catabolism among bacteria.

  BMC evolutionary biology 20090101

• The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens.

  BMC microbiology 20090101

• Genetic polymorphisms of thiopurine S-methyltransferase in a cohort of patients with systemic autoimmune diseases.

  Clinical and experimental rheumatology 20090101

• Cooperation between apoptotic and viable metacyclics enhances the pathogenesis of Leishmaniasis.

  PloS one 20090101

• Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy.

  PloS one 20090101

• Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling.

  BMC genomics 20090101

• What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases.

  Arthritis research & therapy 20090101

• Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion.

  PloS one 20090101

• Genomic characterization of methanomicrobiales reveals three classes of methanogens.

  PloS one 20090101

• 96 shRNAs designed for maximal coverage of HIV-1 variants.

  Retrovirology 20090101

• T-REX: software for the processing and analysis of T-RFLP data.

  BMC bioinformatics 20090101

• Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria.

  Malaria journal 20090101

• Targeted treatment of acute myeloid leukemia in older adults: role of gemtuzumab ozogamicin.

  Clinical interventions in aging 20090101

• [Involvement of angiotensin on adenosine-induced bronchial hyperreactivity].

  Pneumologia (Bucharest, Romania) 20090101

• The repertoire of G-protein-coupled receptors in Xenopus tropicalis.

  BMC genomics 20090101

• SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.

  PloS one 20090101

• Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor.

  BMC structural biology 20090101

• Novel drugs for chronic lymphoid leukemias: mechanism of action and therapeutic activity.

  Current medicinal chemistry 20090101

• Mesothelioma: Do asbestos and carbon nanotubes pose the same health risk?

  Particle and fibre toxicology 20090101

• Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity.

  BMC biochemistry 20090101

• [Peculiarities of uric acid balance disorders in patients with type 2 diabetes and metabolic syndrome].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

• Length and sequence heterogeneity in the mitochondrial internal transcribed spacer of Acanthamoeba spp.

  The Journal of eukaryotic microbiology 20090101

• NTPDases in the neuroendocrine hypothalamus: possible energy regulators of the positive gonadotrophin feedback.

  Reproductive biology and endocrinology : RB&E 20090101

• Gamma-MYN: a new algorithm for estimating Ka and Ks with consideration of variable substitution rates.

  Biology direct 20090101

• Global expression analysis of the brown alga Ectocarpus siliculosus (Phaeophyceae) reveals large-scale reprogramming of the transcriptome in response to abiotic stress.

  Genome biology 20090101

• Statistical assessment of discriminative features for protein-coding and non coding cross-species conserved sequence elements.

  BMC bioinformatics 20090101

• Recent advances in biomedical applications of accelerator mass spectrometry.

  Journal of biomedical science 20090101

• A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability.

  Molecular systems biology 20090101

• [Antibodies to enzymes of purine metabolism as a factor of gastrointestinal tract lesions in systemic scleroderma].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

• Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea.

  Genome biology 20090101

• Metabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathway.

  PloS one 20090101

• Transcriptome adaptation of group B Streptococcus to growth in human amniotic fluid.

  PloS one 20090101

• Joint Arthroplasties other than the Hip in Solid Organ Transplant Recipients.

  The open orthopaedics journal 20090101

• Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.

  BMC structural biology 20090101

• The complex regulation of HIC (Human I-mfa domain containing protein) expression.

  PloS one 20090101

• Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy.

  BMC genomics 20090101

• Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients.

  Annals of Saudi medicine 20090101

• Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes.

  Frontiers in neuroenergetics 20090101

• Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model.

  BMC genomics 20090101

• In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent.

  Metal-based drugs 20090101

• Oxidative stress, thermogenesis and evolution of uncoupling proteins.

  Journal of biology 20090101

• Comparing 2-nt 3' overhangs against blunt-ended siRNAs: a systems biology based study.

  BMC genomics 20090101

• Word-based characterization of promoters involved in human DNA repair pathways.

  BMC genomics 20090101

• Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen.

  BMC genomics 20090101

• Dynamic expression pattern of distinct genes in the presomitic and somitic mesoderm during Xenopus development.

  The International journal of developmental biology 20090101

• Regression based predictor for p53 transactivation.

  BMC bioinformatics 20090101

• Cross-packaging of genetically distinct mouse and primate retroviral RNAs.

  Retrovirology 20090101

• Ticagrelor: the first reversibly binding oral P2Y12 receptor antagonist.

  Cardiovascular therapeutics 20090101

• Do uric acid deposits in zooxanthellae function as eye-spots?

  PloS one 20090101

• Update in the management of chronic lymphocytic leukemia.

  Journal of hematology & oncology 20090101

• Bacillus subtilis as potential producer for polyhydroxyalkanoates.

  Microbial cell factories 20090101

• DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR.

  BMC molecular biology 20090101

• The activities of paraoxonase, xanthine oxidase, adenosine deaminase and the level of nitrite in pseudoexfoliation syndrome.

  Ophthalmic research 20090101

• The first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxia.

  PloS one 20090101

• Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis.

  Arthritis research & therapy 20090101

• Hidden chromosome symmetry: in silico transformation reveals symmetry in 2D DNA walk trajectories of 671 chromosomes.

  PloS one 20090101

• Bacillus cereus spores release alanine that synergizes with inosine to promote germination.

  PloS one 20090101

• Adenosine receptors and neurological disease: neuroprotection and neurodegeneration.

  Handbook of experimental pharmacology 20090101

• Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model.

  BMC cancer 20090101

• Hydrogen bonding and packing density are factors most strongly connected to limiting sites of high flexibility in the 16S rRNA in the 30S ribosome.

  BMC structural biology 20090101

• Stretches of alternating pyrimidine/purines and purines are respectively linked with pathogenicity and growth temperature in prokaryotes.

  BMC genomics 20090101

• Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933.

  BMC genomics 20090101

• Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data.

  BMC medical genomics 20090101

• Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype.

  PloS one 20090101

• Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions.

  BMC veterinary research 20090101

• Regulation of MicroRNA Biogenesis: A miRiad of mechanisms.

  Cell communication and signaling : CCS 20090101

• Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity.

  BMC bioinformatics 20090101

• Genome-wide screen of genes required for caffeine tolerance in fission yeast.

  PloS one 20090101

• Evaluating graft function in pediatric recipients for living donor renal transplantation: Is laparoscopic donor nephrectomy safe?

  Indian journal of urology : IJU : journal of the Urological Society of India 20090101

• MouseCyc: a curated biochemical pathways database for the laboratory mouse.

  Genome biology 20090101

• Advances in maize genomics and their value for enhancing genetic gains from breeding.

  International journal of plant genomics 20090101

• Genome-scale gene/reaction essentiality and synthetic lethality analysis.

  Molecular systems biology 20090101

• Pharmacokinetic optimization of immunosuppressive therapy in thoracic transplantation: part I.

  Clinical pharmacokinetics 20090101

• Genetic and molecular basis of individual differences in human umami taste perception.

  PloS one 20090101

• On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth.

  Biology direct 20090101

• Management strategies for pulmonary sarcoidosis.

  Therapeutics and clinical risk management 20090101

• Managing pediatric hepatitis C: current and emerging treatment options.

  Therapeutics and clinical risk management 20090101

• Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency.

  Biologics : targets & therapy 20090101

• Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID).

  Biologics : targets & therapy 20090101

• Chemotherapy of human african trypanosomiasis.

  Interdisciplinary perspectives on infectious diseases 20090101

• MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.

  PloS one 20090101

• Preparation of group I introns for biochemical studies and crystallization assays by native affinity purification.

  PloS one 20090101

• Activities of adenosine deaminase and 5'-nucleotidase in cancereous and non-cancereous human gastric tissues.

  Bratislavske lekarske listy 20090101

• Empirical relationship between intra-purine and intra-pyrimidine differences in conserved gene sequences.

  PloS one 20090101

• Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance.

  Journal of translational medicine 20090101

• A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling.

  PloS one 20090101

• Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway.

  PloS one 20090101

• Targeting the purinome.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Sequence features associated with microRNA strand selection in humans and flies.

  BMC genomics 20090101

• Synthesis, spectroscopic and thermal characterization of copper(II) and iron(III) complexes of folic acid and their absorption efficiency in the blood.

  Bioinorganic chemistry and applications 20090101

• Adenosine and adenosine receptors: their contribution to airway inflammation and therapeutic potential in asthma.

  Current medicinal chemistry 20090101

• Idiopathic recurrent calcium urolithiasis (IRCU): variation of fasting urinary protein is a window to pathophysiology or simple consequence of renal stones in situ? A tripartite study in male patients providing insight into oxidative metabolism as possible driving force towards alteration of urine composition, calcium salt crystallization and stone formation.

  European journal of medical research 20090101

• Alternative I-D exchange reaction on pyrimidine and purine nuclei mediated by tributyltin hydride using THF-d8 as a deuterium source.

  Nucleic acids symposium series (2004) 20090101

• Mycophenolic acid formulations in adult renal transplantation - update on efficacy and tolerability.

  Therapeutics and clinical risk management 20090101

• Involvement of A(1) adenosine receptors in osmotic volume regulation of retinal glial cells in mice.

  Molecular vision 20090101

• Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function.

  Genome biology 20090101

• The NlpD lipoprotein is a novel Yersinia pestis virulence factor essential for the development of plague.

  PloS one 20090101

• Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine.

  PloS one 20090101

• Alterations in adenylate kinase activity in human PBMCs after in vitro exposure to electromagnetic field: comparison between extremely low frequency electromagnetic field (ELF) and therapeutic application of a musically modulated electromagnetic field (TAMMEF).

  Journal of biomedicine & biotechnology 20090101

• Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer.

  BMC genomics 20090101

• Synergistic role of hydroxyapatite nanoparticles and pulsed electromagnetic field therapy to prevent bone loss in rats following exposure to simulated microgravity.

  International journal of nanomedicine 20090101

• A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis.

  BMC neuroscience 20090101

• T-cell prolymphocytic leukemia.

  Clinical lymphoma & myeloma 20090101

• Immunomodulation with methotrexate: underused and undervalued?

  Digestive diseases (Basel, Switzerland) 20090101

• Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

  PloS one 20090101

• Carbohydrate metabolism and carbon fixation in Roseobacter denitrificans OCh114.

  PloS one 20090101

• Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae.

  BMC genomics 20090101

• Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions.

  Genome biology 20090101

• SigWinR; the SigWin-detector updated and ported to R.

  BMC research notes 20090101

• Refinement of lentiviral vector for improved RNA processing and reduced rates of self inactivation repair.

  BMC biotechnology 20090101

• A man-made ATP-binding protein evolved independent of nature causes abnormal growth in bacterial cells.

  PloS one 20090101

• KEGGconverter: a tool for the in-silico modelling of metabolic networks of the KEGG Pathways database.

  BMC bioinformatics 20090101

• Riboswitch detection using profile hidden Markov models.

  BMC bioinformatics 20090101

• Environmental and intracellular regulation of Francisella tularensis ripA.

  BMC microbiology 20090101

• NK cell-mediated cytotoxicity modulation by A(2) adenosine receptor agonist in different mammalian species.

  Folia microbiologica 20090101

• Differential changes in serum uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial.

  Nutrition & metabolism 20090101

• Genome-wide transcriptome analyses of silicon metabolism in Phaeodactylum tricornutum reveal the multilevel regulation of silicic acid transporters.

  PloS one 20090101

• Different responsiveness to a high-fat/cholesterol diet in two inbred mice and underlying genetic factors: a whole genome microarray analysis.

  Nutrition & metabolism 20090101

• Elements regulating Potato leafroll virus sgRNA1 translation are located within the coding sequences of the coat protein and read-through domain.

  Acta biochimica Polonica 20090101

• 2'-Benzoyloxycinnamaldehyde inhibits tumor growth in H-ras12V transgenic mice via downregulation of metallothionein.

  Nutrition and cancer 20090101

• Arabidopsis gene co-expression network and its functional modules.

  BMC bioinformatics 20090101

• Metabolomic profiling in LRRK2-related Parkinson's disease.

  PloS one 20090101

• Reduction of nitrogen compounds in oceanic basement and its implications for HCN formation and abiotic organic synthesis.

  Geochemical transactions 20090101

• The role of urate and xanthine oxidase in vascular oxidative stress: future directions.

  Therapeutics and clinical risk management 20090101

• Comparative transcriptional survey between laser-microdissected cells from laminar abscission zone and petiolar cortical tissue during ethylene-promoted abscission in citrus leaves.

  BMC plant biology 20090101

• Purine-scaffold Hsp90 inhibitors.

  Current topics in medicinal chemistry 20090101

• The role of UPF0157 in the folding of M. tuberculosis dephosphocoenzyme A kinase and the regulation of the latter by CTP.

  PloS one 20090101

• Hepatic gene expression profiling reveals protective responses in Atlantic salmon vaccinated against furunculosis.

  BMC genomics 20090101

• Effects of methotrexate on plasma cytokines and cardiac remodeling and function in postmyocarditis rats.

  Mediators of inflammation 20090101

• DNA damage/repair and polymorphism of the hOGG1 gene in lymphocytes of AMD patients.

  Journal of biomedicine & biotechnology 20090101

• A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus.

  PloS one 20090101

• Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects.

  PloS one 20090101

• Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan.

  Journal of negative results in biomedicine 20090101

• [A theoretical investigation of tautomerism of adenine, purine, guanine, and cytosine].

  Biofizika 20090101

• SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights.

  BMC genomics 20090101

• Current trends in the management of ocular symptoms in Adamantiades-Behçet's disease.

  Clinical ophthalmology (Auckland, N.Z.) 20090101

• Functional phosphoproteomic profiling of phosphorylation sites in membrane fractions of salt-stressed Arabidopsis thaliana.

  Proteome science 20090101

• Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads.

  Retrovirology 20090101

• Current and emerging treatments for chronic lymphocytic leukaemia.

  Drugs 20090101

• Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypes.

  BMC evolutionary biology 20090101

• A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae.

  BMC genomics 20090101

• Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase.

  BMC systems biology 20090101

• Analysis of HSP90-related folds with MED-SuMo classification approach.

  Drug design, development and therapy 20090101

• T10B9 monoclonal antibody: a short-acting nonstimulating monoclonal antibody that spares gammadelta T-cells and treats and prevents cellular rejection.

  Drug design, development and therapy 20090101

• Identification of an exonic splicing silencer in exon 6A of the human VEGF gene.

  BMC molecular biology 20090101

• Exceptional error minimization in putative primordial genetic codes.

  Biology direct 20090101

• Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers.

  BMC cancer 20090101

• Identifying quantitative operation principles in metabolic pathways: a systematic method for searching feasible enzyme activity patterns leading to cellular adaptive responses.

  BMC bioinformatics 20090101

• Genome-wide analysis of immune activation in human T and B cells reveals distinct classes of alternatively spliced genes.

  PloS one 20090101

• Generation and characterization of FMR1 knockout zebrafish.

  PloS one 20090101

• Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion.

  Reproductive biology and endocrinology : RB&E 20090101

• Effects of Kombucha on oxidative stress induced nephrotoxicity in rats.

  Chinese medicine 20090101

• JANE: efficient mapping of prokaryotic ESTs and variable length sequence reads on related template genomes.

  BMC bioinformatics 20090101

• Recent advances in the pathogenesis of syndromic autisms.

  International journal of pediatrics 20090101

• Diagnosis of invasive aspergillus tracheobronchitis facilitated by endobronchial ultrasound-guided transbronchial needle aspiration: a case report.

  Journal of medical case reports 20090101

• Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts.

  BMC genomics 20090101

• Purinergic mechanosensory transduction and visceral pain.

  Molecular pain 20090101

• Transcriptomic response of the mycoparasitic fungus Trichoderma atroviride to the presence of a fungal prey.

  BMC genomics 20090101

• Examination of genome homogeneity in prokaryotes using genomic signatures.

  PloS one 20090101

• A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus infection.

  PloS one 20090101

• Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.

  PloS one 20090101

• Critical appraisal of the MTT assay in the presence of rottlerin and uncouplers.

  Biological procedures online 20090101

• Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT.

  Journal of experimental & clinical cancer research : CR 20090101

• Drug-induced hematologic syndromes.

  Advances in hematology 20090101

• Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.

  PloS one 20090101

• Phenotypic characterisation and ZEB1 mutational analysis in posterior polymorphous corneal dystrophy in a New Zealand population.

  Molecular vision 20090101

• Loss of the histone pre-mRNA processing factor stem-loop binding protein in Drosophila causes genomic instability and impaired cellular proliferation.

  PloS one 20090101

• Immune hemolytic anemia--selected topics.

  Hematology. American Society of Hematology. Education Program 20090101

• Allotransplantation for chronic lymphocytic leukemia.

  Hematology. American Society of Hematology. Education Program 20090101

• Influence of sex on gene expression in human corneal epithelial cells.

  Molecular vision 20090101

• Assessing the utility of whole-genome amplified serum DNA for array-based high throughput genotyping.

  BMC genetics 20090101

• The potential for xanthine oxidase inhibition in the prevention and treatment of cardiovascular and cerebrovascular disease.

  Cardiovascular psychiatry and neurology 20090101

• Conservation of DNA-binding specificity and oligomerisation properties within the p53 family.

  BMC genomics 20090101

• Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.

  Retrovirology 20090101

• The malate synthase of Paracoccidioides brasiliensis is a linked surface protein that behaves as an anchorless adhesin.

  BMC microbiology 20090101

• Molecular evolution of the hyperthermophilic archaea of the Pyrococcus genus: analysis of adaptation to different environmental conditions.

  BMC genomics 20090101

• Quantitative analysis of replication-related mutation and selection pressures in bacterial chromosomes and plasmids using generalised GC skew index.

  BMC genomics 20090101

• Montelukast does not inhibit the late phase reaction in Parthenium dermatitis.

  Indian journal of dermatology 20090101

• Mizoribine: a new approach in the treatment of renal disease.

  Clinical & developmental immunology 20090101

• Treatment options for ocular adnexal lymphoma (OAL).

  Clinical ophthalmology (Auckland, N.Z.) 20090101

• Development of fludarabine formulations in the treatment of chronic lymphocytic leukemia.

  Drug design, development and therapy 20090101

• Severe encephalopathy with brain atrophy and hypomyelination due to adenylosuccinate lyase deficiency--MRI, clinical, biochemical and neuropathological findings of Polish patients.

  Folia neuropathologica 20090101

• What lies behind serum urate concentration? Insights from genetic and genomic studies.

  Genome medicine 20090101

• A comprehensive review of immunosuppression used for liver transplantation.

  Journal of transplantation 20090101

• Classifying coding DNA with nucleotide statistics.

  Bioinformatics and biology insights 20090101

• Universal Features for the Classification of Coding and Non-coding DNA Sequences.

  Bioinformatics and biology insights 20090101

• Inferring Transcriptional Interactions by the Optimal Integration of ChIP-chip and Knock-out Data.

  Bioinformatics and biology insights 20090101

• Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock.

  Journal of cheminformatics 20090101

• Disease-modifying agents in multiple sclerosis.

  Annals of Indian Academy of Neurology 20090101

• Promising treatments of tomorrow for multiple sclerosis.

  Annals of Indian Academy of Neurology 20090101

• [Hyperuricemia and the metabolic syndrome].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20090101

• [Enzymatic transglycosylation of natural and modified nucleosides by immobilized thermostable nucleoside phosphorylases from Geobacillus stearothermophilus].

  Bioorganicheskaia khimiia 20090101

• 2, 8 Dihydroxyadenine urolithiasis: A case report and review of literature.

  Indian journal of nephrology 20090101

• Urate oxidase knockdown decreases oxidative stress in a murine hepatic cell line.

  Oxidative medicine and cellular longevity 20090101

• Immunoregulation through IL-10 gene expression and the fate of cytotoxic T lymphocyte-mediated tumor immunotherapy.

  Indian journal of human genetics 20090101

• mGluR(1) Receptors Contribute to Non-Purinergic Slow Excitatory Transmission to Submucosal VIP Neurons of Guinea-Pig Ileum.

  Frontiers in neuroscience 20090101

• Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia.

  OncoTargets and therapy 20090101

• Bendamustine in the treatment of non-Hodgkin's lymphomas.

  OncoTargets and therapy 20090101

• Tumor markers in clinical practice: General principles and guidelines.

  Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20090101

• Febuxostat: the evidence for its use in the treatment of hyperuricemia and gout.

  Core evidence 20090101

• Oxidative stress as a mediator of cardiovascular disease.

  Oxidative medicine and cellular longevity 20090101

• Purinergic cotransmission.

  F1000 biology reports 20090101

• New oral disease-modifying therapies for multiple sclerosis.

  F1000 medicine reports 20090101

• The role of bendamustine in the treatment of indolent non-Hodgkin lymphoma.

  Cancer management and research 20090101

• A Comparative Study of Metabolic Network Topology between a Pathogenic and a Non-Pathogenic Bacterium for Potential Drug Target Identification.

  Summit on translational bioinformatics 20090101

• Introducing mediterranean journal of hematology and infectious diseases.

  Mediterranean journal of hematology and infectious diseases 20090101

• EBV in Hodgkin Lymphoma.

  Mediterranean journal of hematology and infectious diseases 20090101

• Tacrolimus ointment in the management of atopic dermatitis.

  Clinical, cosmetic and investigational dermatology 20090101

• New concepts of fluorescent probes for specific detection of DNA sequences: bis-modified oligonucleotides in excimer and exciplex detection.

  The Libyan journal of medicine 20090101

• Altered expression of the caffeine synthase gene in a naturally caffeine-free mutant of Coffea arabica.

  Genetics and molecular biology 20090101

• Comparative analysis of the genes UL1 through UL7 of the duck enteritis virus and other herpesviruses of the subfamily Alphaherpesvirinae.

  Genetics and molecular biology 20090101

• Xylella fastidiosa gene expression analysis by DNA microarrays.

  Genetics and molecular biology 20090101

• The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthoraperniciosa, the causal agent of witches' broom disease of Theobroma cacao.

  Genetics and molecular biology 20090101

• Escherichia coli, an Intestinal Microorganism, as a Biosensor for Quantification of Amino Acid Bioavailability.

  Sensors (Basel, Switzerland) 20090101

• Effects of malic acid on rumen fermentation, urinary excretion of purine derivatives and feed digestibility in steers.

  Animal : an international journal of animal bioscience 20090101

• Study of Interactions between Metallothionein and Cisplatin by using Differential Pulse Voltammetry Brdickás reaction and Quartz Crystal Microbalance.

  Sensors (Basel, Switzerland) 20090101

• Overview of electrochemical DNA biosensors: new approaches to detect the expression of life.

  Sensors (Basel, Switzerland) 20090101

• The interrelationship of helicase and nuclease domains during DNA translocation by the molecular motor EcoR124I.

  Journal of molecular biology 20081231

• Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase.

  The Journal of biological chemistry 20081226

• Guanine radical reaction processes: a computational description of proton transfer in X-irradiated 9-ethylguanine single crystals.

  The journal of physical chemistry. B 20081225

• In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase.

  Chemistry & biology 20081222

• Hemodynamic variables and clinical features correlated with serum uric acid in patients with pulmonary arterial hypertension.

  Chinese medical journal 20081220

• Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites.

  The Journal of biological chemistry 20081219

• Simulation study of noncovalent hybridization of carbon nanotubes by single-stranded DNA in water.

  The journal of physical chemistry. B 20081218

• 3' terminal nucleotides determine thermodynamic stabilities of mismatches at the ends of RNA helices.

  Biochemistry 20081216

• Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase.

  Archives of biochemistry and biophysics 20081215

• Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis.

  Journal of medicinal chemistry 20081211

• An ab initio study of substituent effects on the excited states of purine derivatives.

  The journal of physical chemistry. A 20081204

• Recent improvements in the development of A(2B) adenosine receptor agonists.

  Purinergic signalling 20081201

• Purinergic-mediated Ca2+ influx in Dictyostelium discoideum.

  Cell calcium 20081201

• Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.

  Blood 20081201

• D-ribose therapy in four Polish patients with adenylosuccinate lyase deficiency: absence of positive effect.

  Journal of inherited metabolic disease 20081201

• Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081201

• Pleiotropic effects of selective CDK inhibitors on human normal and cancer cells.

  Biochemical pharmacology 20081201

• 5'-p-Fluorosulfonyl benzoyl adenosine inhibits an ecto-ATP-diphosphohydrolase in the tegument surface of Taenia crassiceps cysticerci.

  Molecular and biochemical parasitology 20081201

• UTP and ATP increase extracellular signal-regulated kinase 1/2 phosphorylation in bovine chromaffin cells through epidermal growth factor receptor transactivation.

  Purinergic signalling 20081201

• Evidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and insulin secretion in mouse pancreatic islets.

  Purinergic signalling 20081201

• Repair of deaminated base damage by Schizosaccharomyces pombe thymine DNA glycosylase.

  DNA repair 20081201

• Pharmacodynamics of mycophenolic acid in CD4+ cells: a single-dose study of IMPDH and purine nucleotide responses in healthy individuals.

  Therapeutic drug monitoring 20081201

• A computational study of expanded heterocyclic nucleosides in DNA.

  Journal of biomolecular structure & dynamics 20081201

• Failure to upregulate the adenosine2A receptor-epoxyeicosatrienoic acid pathway contributes to the development of hypertension in Dahl salt-sensitive rats.

  American journal of physiology. Renal physiology 20081201

• Characterization of cytokinin and adenine transport in Arabidopsis cell cultures.

  Plant physiology 20081201

• Effects of excitatory and inhibitory neurotransmission on motor patterns of human sigmoid colon in vitro.

  British journal of pharmacology 20081201

• Regulation of enteric functions by adenosine: pathophysiological and pharmacological implications.

  Pharmacology & therapeutics 20081201

• Lentivirus gene therapy for purine nucleoside phosphorylase deficiency.

  The journal of gene medicine 20081201

• A genome-wide and metabolic analysis determined the adaptive response of Arabidopsis cells to folate depletion induced by methotrexate.

  Plant physiology 20081201

• Folate status in various pathophysiological conditions.

  IUBMB life 20081201

• Characterization of the DNA adducts induced by aristolochic acids in oligonucleotides by electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20081201

• Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines.

  Nature genetics 20081201

• Effectiveness of the fatty acid and sterol composition of seeds for the chemotaxonomy of Coffea subgenus Coffea.

  Phytochemistry 20081201

• Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20081201

• Hypoxanthine-guanine phosphoribosylotransferase deficiency--the spectrum of Polish mutations.

  Journal of inherited metabolic disease 20081201

• Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases.

  Journal of immunology (Baltimore, Md. : 1950) 20081201

• A novel nucleoside kinase from Burkholderia thailandensis: a member of the phosphofructokinase B-type family of enzymes.

  The FEBS journal 20081201

• Tezosentan, a novel endothelin receptor antagonist, markedly reduces rat hepatic ischemia and reperfusion injury in three different models.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20081201

• Effect on production of replacing dietary starch with sucrose in lactating dairy cows.

  Journal of dairy science 20081201

• Arthrobacter oxydans as a biocatalyst for purine deamination.

  FEMS microbiology letters 20081201

• Lactobacillus phylogenomics--towards a reclassification of the genus.

  International journal of systematic and evolutionary microbiology 20081201

• A comparison of vitamin A and leucovorin for the prevention of methotrexate-induced micronuclei production in rat bone marrow.

  Clinics (Sao Paulo, Brazil) 20081201

• Novel therapies for cutaneous T-cell lymphomas.

  Clinical lymphoma & myeloma 20081201

• Human cytomegalovirus IE1 protein enhances herpes simplex virus type 1-induced syncytial formation in U373MG cells.

  Journal of Korean medical science 20081201

• Decreasing mortality from non-Hodgkin lymphoma in Australia.

  Internal medicine journal 20081201

• Induction of protective immunity against Burkholderia pseudomallei using attenuated mutants with defects in the intracellular life cycle.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20081201

• The role for S-carboxymethylcysteine (carbocisteine) in the management of chronic obstructive pulmonary disease.

  International journal of chronic obstructive pulmonary disease 20081201

• Febuxostat in the management of hyperuricemia and chronic gout: a review.

  Therapeutics and clinical risk management 20081201

• Hormonal and biochemical parameters of metabolic syndrome in male patients with body weight excess and obesity.

  Bulletin of experimental biology and medicine 20081201

• Activity-dependent release of adenosine: a critical re-evaluation of mechanism.

  Current neuropharmacology 20081201

• Bis[5-oxo-4,5-dihydro-8H-2-azonia-4,8,9-trizabicyclo[4.3.0]nona-2,6,9(1)-triene] sulfate.

  Acta crystallographica. Section E, Structure reports online 20081201

• Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum.

  The Journal of biological chemistry 20081121

• Synthesis and degradation of nucleic acid components by formamide and iron sulfur minerals.

  Journal of the American Chemical Society 20081119

• Effects of nucleobase metalation on frontier molecular orbitals: potential implications for pi-stacking interactions with tryptophan.

  Inorganic chemistry 20081117

• Adenosine produced by neurons is metabolized to hypoxanthine by astrocytes.

  Journal of neuroscience research 20081115

• Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells.

  International journal of cancer 20081115

• Mapping the subunit interface of ribonucleotide reductase (RNR) using photo cross-linking.

  Bioorganic & medicinal chemistry letters 20081115

• Immucillins in custom catalytic-site cavities.

  Bioorganic & medicinal chemistry letters 20081115

• The GANC tetraloop: a novel motif in the group IIC intron structure.

  Journal of molecular biology 20081114

• X-ray absorption spectroscopy of the nucleotide bases at the carbon, nitrogen, and oxygen K-edges.

  The journal of physical chemistry. B 20081106

• The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.

  Biochemistry 20081104

• Synthesis and pharmacological screening of derivatives of isoxazolo[4,5-d]pyrimidine.

  European journal of medicinal chemistry 20081101

• Crohn's disease: factors associated with exposure to high levels of diagnostic radiation.

  Gut 20081101

• Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain?

  Brain, behavior, and immunity 20081101

• Thermodynamics of single strand DNA base stacking.

  Biopolymers 20081101

• Allopurinol, an inhibitor of purine catabolism, enhances susceptibility of tobacco to Tobacco mosaic virus.

  Virus research 20081101

• Is ZMP the toxic metabolite in Lesch-Nyhan disease?

  Medical hypotheses 20081101

• Structural biology of the purine biosynthetic pathway.

  Cellular and molecular life sciences : CMLS 20081101

• Chemical substructures that enrich for biological activity.

  Bioinformatics (Oxford, England) 20081101

• Structural studies of human purine nucleoside phosphorylase: towards a new specific empirical scoring function.

  Archives of biochemistry and biophysics 20081101

• In situ measurements of aggregation and disaggregation of Cu(II) complex at liquid/liquid interface.

  Analytical chemistry 20081101

• Effect of local sugar and base geometry on 13C and 15N magnetic shielding anisotropy in DNA nucleosides.

  Journal of biomolecular NMR 20081101

• Inner-shell chemical shift of DNA/RNA bases and inheritance from their parent purine and pyrimidine.

  Journal of synchrotron radiation 20081101

• Mutations in the SLC2A9 gene cause hyperuricosuria and hyperuricemia in the dog.

  PLoS genetics 20081101

• A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.

  PLoS pathogens 20081101

• Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice.

  Journal of cardiac failure 20081101

• Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

  PLoS genetics 20081101

• A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.

  PLoS genetics 20081101

• Strong short-range correlations and dichotomic codon classes in coding DNA sequences.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20081101

• Formation of xanthine and the use of purine metabolites as a nitrogen source in Arabidopsis plants.

  Plant signaling & behavior 20081101

• Hairy Cell Leukaemia in Oman: Four cases.

  Sultan Qaboos University medical journal 20081101

• Identification of osteogenic purmorphamine derivatives.

  Molecules and cells 20081031

• Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage.

  European journal of pharmacology 20081031

• Low-dose methotrexate therapy for intravenous immunoglobulin-resistant Kawasaki disease.

  Yonsei medical journal 20081031

• The role of external and matrix pH in mitochondrial reactive oxygen species generation.

  The Journal of biological chemistry 20081024

• Effect of the ribose versus 2'-deoxyribose residue on the metal ion-binding properties of purine nucleotides.

  Dalton transactions (Cambridge, England : 2003) 20081021

• Photogeneration of 2-deoxyribonolactone in benzophenone-purine dyads. Formation of ketyl-C1' biradicals.

  Organic letters 20081016

• 7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.

  Biochemical pharmacology 20081015

• TNAP, TrAP, ecto-purinergic signaling, and bone remodeling.

  Journal of cellular biochemistry 20081015

• Fe(II)/alpha-ketoglutarate hydroxylases involved in nucleobase, nucleoside, nucleotide, and chromatin metabolism.

  Dalton transactions (Cambridge, England : 2003) 20081014

• Identification and characterization of a new Leishmania major specific 3'nucleotidase/nuclease protein.

  Biochemical and biophysical research communications 20081010

• Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor.

  Virology 20081010

• Antinociceptive effects of intracerebroventricular administration of guanine-based purines in mice: evidences for the mechanism of action.

  Brain research 20081009

• DNA with stable fluorinated dA and dG substitutes: syntheses, base pairing and 19F-NMR spectra of 7-fluoro-7-deaza-2'-deoxyadenosine and 7-fluoro-7-deaza-2'-deoxyguanosine.

  Organic & biomolecular chemistry 20081007

• Overexpression, purification and characterization of functional calf purine nucleoside phosphorylase (PNP).

  Protein expression and purification 20081001

• Dysregulation of purine nucleotide biosynthesis pathways modulates cisplatin cytotoxicity in Saccharomyces cerevisiae.

  Molecular pharmacology 20081001

• Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum.

  Molecular and biochemical parasitology 20081001

• Characteristics and prediction of RNA editing sites in transcripts of the Moss Takakia lepidozioides chloroplast.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20081001

• Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis.

  Journal of the American Society for Mass Spectrometry 20081001

• Construction of signature-tagged mutant library in Mesorhizobium loti as a powerful tool for functional genomics.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20081001

• In vitro polydeoxyribonucleotide effects on human pre-adipocytes.

  Cell proliferation 20081001

• AMP hydrolysis in soluble and microsomal rat cardiac cell fractions: kinetic characterization and molecular identification of 5'-nucleotidase.

  Bioscience reports 20081001

• Interaction of the DNA bases and their mononucleotides with pyridine-2-carbaldehyde thiosemicarbazonecopper(II) complexes. Structure of the cytosine derivative.

  Journal of inorganic biochemistry 20081001

• Ascendancy of weekly low-dose methotrexate in usual care of rheumatoid arthritis from 1980 to 2004 at two sites in Finland and the United States.

  Rheumatology (Oxford, England) 20081001

• Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells.

  Biochimica et biophysica acta 20081001

• Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator.

  Molecular microbiology 20081001

• Protein cooperation: from neurons to networks.

  Progress in neurobiology 20081001

• Kinase array design, back to front: biaryl amides.

  Bioorganic & medicinal chemistry letters 20081001

• Hairy cell leukemia: current concepts.

  Cancer investigation 20081001

• Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Treatment of human African trypanosomiasis with natural products (Review).

  International journal of molecular medicine 20081001

• The relative merit of ruminal undegradable protein from soybean meal or soluble fiber from beet pulp to improve nitrogen utilization in dairy cows.

  Journal of dairy science 20081001

• [Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001

• SLC2A9 is a high-capacity urate transporter in humans.

  PLoS medicine 20081001

• FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells.

  Molecular cancer therapeutics 20081001

• Effects of isobutyrate on rumen fermentation, urinary excretion of purine derivatives and digestibility in steers.

  Archives of animal nutrition 20081001

• Extracellular ATP-induced NO production and its dependence on membrane Ca2+ flux in Salvia miltiorrhiza hairy roots.

  Journal of experimental botany 20081001

• 7-Dimethyl-amino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol solvate.

  Acta crystallographica. Section E, Structure reports online 20081001

• A beta-fluoroamine inhibitor of purine nucleoside phosphorylase.

  Journal of medicinal chemistry 20080925

• Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways.

  The EMBO journal 20080917

• Uric acid in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20080915

• MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization.

  Bioinformatics (Oxford, England) 20080915

• Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI.

  Chemical research in toxicology 20080915

• Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2.

  Chemical research in toxicology 20080915

• P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response.

  Cancer research 20080915

• Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.

  Journal of molecular biology 20080912

• Functional chimeras of the phosphodiesterase 5 and 10 tandem GAF domains.

  The Journal of biological chemistry 20080912

• New phenolic components and chromatographic profiles of green and fermented teas.

  Journal of agricultural and food chemistry 20080910

• Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910

• A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3.

  The Journal of biological chemistry 20080905

• Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.

  Journal of the American Chemical Society 20080903

• Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells.

  British journal of cancer 20080902

• Presence of epidermal allantoin further supports oxidative stress in vitiligo.

  Experimental dermatology 20080901

• Purinergic receptors and synaptic transmission in enteric neurons.

  Purinergic signalling 20080901

• Purinergic mechanisms in the control of gastrointestinal motility.

  Purinergic signalling 20080901

• Pancreatic cancer: from molecular pathogenesis to targeted therapy.

  Cancer metastasis reviews 20080901

• Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.

  The Biochemical journal 20080901

• Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons.

  Free radical biology & medicine 20080901

• The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.

  The Journal of endocrinology 20080901

• Extracellular ATP and cancer: an overview with special reference to P2 purinergic receptors.

  Pathology oncology research : POR 20080901

• DNA binding by Ru(II)-bis(bipyridine)-pteridinyl complexes.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080901

• Genes and networks expressed in perioperative omental adipose tissue are correlated with weight loss from Roux-en-Y gastric bypass.

  International journal of obesity (2005) 20080901

• Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors.

  Bioorganic & medicinal chemistry letters 20080901

• Design and SAR of new substituted purines bearing aryl groups at N9 position as HIV-1 Tat-TAR interaction inhibitors.

  Bioorganic & medicinal chemistry 20080901

• The use of 10-23 DNAzyme to selectively destroy the allele of mRNA with a unique purine-pyrimidine dinucleotide.

  Oligonucleotides 20080901

• [Do folates have an impact on fertility?].

  Gynecologie, obstetrique & fertilite 20080901

• Pentostatin in chronic lymphocytic leukemia.

  Expert opinion on drug metabolism & toxicology 20080901

• UVC induced oxidation of chloropurines: excited singlet and triplet pathways for the photoreaction.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080901

• Lactobacillus plantarum response to inorganic carbon concentrations: PyrR2-dependent and -independent transcription regulation of genes involved in arginine and nucleotide metabolism.

  Microbiology (Reading, England) 20080901

• Sustained contraction and endothelial dysfunction induced by reactive oxygen species in porcine coronary artery.

  Biological & pharmaceutical bulletin 20080901

• Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity.

  Nature medicine 20080901

• Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.

  Arthritis and rheumatism 20080901

• The effect of feeding dried distillers grains plus solubles on milk production and excretion of urinary purine derivatives.

  Journal of dairy science 20080901

• Rumen digestion and nutritional efficiency of dairy heifers limit-fed a high forage ration to four levels of dry matter intake.

  Journal of dairy science 20080901

• Variable expression of HPRT deficiency in 5 members of a family with the same mutation.

  Archives of neurology 20080901

• Hydrophilic interaction chromatography in nonaqueous elution mode for separation of hydrophilic analytes on silica-based packings with noncharged polar bondings.

  Journal of separation science 20080901

• The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii.

  PLoS genetics 20080901

• [Monitoring of immunosuppressant drugs].

  Therapeutische Umschau. Revue therapeutique 20080901

• FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae.

  PLoS genetics 20080901

• Needles in the EST haystack: large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using expressed sequence tags (ESTs).

  PLoS neglected tropical diseases 20080901

• Capturing hammerhead ribozyme structures in action by modulating general base catalysis.

  PLoS biology 20080901

• Infliximab in ulcerative colitis.

  Biologics : targets & therapy 20080901

• Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia.

  Biologics : targets & therapy 20080901

• Photophysical characters of rationally designed hetero-ring-expanded guanine analogues and effect of cytosine pairing.

  The journal of physical chemistry. B 20080828

• Rearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA.

  Journal of the American Chemical Society 20080820

• A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.

  Biochemistry 20080819

• The purine machine scores a base hit.

  ACS chemical biology 20080815

• Pathway engineered enzymatic de novo purine nucleotide synthesis.

  ACS chemical biology 20080815

• Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots.

  The journal of physical chemistry. B 20080814

• Binding to DNA purine base and structure-activity relationship of a series of structurally related Ru(II) antitumor complexes: a theoretical study.

  The journal of physical chemistry. B 20080814

• A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.

  The Journal of biological chemistry 20080808

• Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV.

  Biochemistry 20080805

• Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines.

  European journal of medicinal chemistry 20080801

• Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.

  Leukemia research 20080801

• Knockdown of cytosolic 5'-nucleotidase II (cN-II) reveals that its activity is essential for survival in astrocytoma cells.

  Biochimica et biophysica acta 20080801

• Molecular characterization, heterologous expression and kinetic analysis of recombinant Plasmodium falciparum thymidylate kinase.

  Journal of biochemistry 20080801

• Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI.

  Diabetes care 20080801

• Superstructural self-assembly of the G-quadruplex structure formed by the homopurine strand in a DNA tract of human telomerase gene promoter.

  Biophysical chemistry 20080801

• Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX.

  Rheumatology (Oxford, England) 20080801

• Human rheumatoid synoviocytes express functional P2X7 receptors.

  Journal of molecular medicine (Berlin, Germany) 20080801

• Purine salvage pathways in the intraerythrocytic malaria parasite Plasmodium falciparum.

  Eukaryotic cell 20080801

• p42/44 MAPK is an essential effector for purine nucleoside-mediated neuroprotection of hypoxic PC12 cells and primary cerebellar granule neurons.

  Molecular and cellular neurosciences 20080801

• Fine targeting of purine salvage in Cryptosporidium parasites.

  Trends in parasitology 20080801

• Molecular and functional mapping of regional differences in P2Y receptor expression in the rat lens.

  Experimental eye research 20080801

• Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway.

  The Journal of physiology 20080801

• Structures of Arthrobacter globiformis urate oxidase-ligand complexes.

  Acta crystallographica. Section D, Biological crystallography 20080801

• Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.

  Archives of toxicology 20080801

• Acadesine, an adenosine-regulating agent with the potential for widespread indications.

  Expert opinion on pharmacotherapy 20080801

• Structure of the Brachydanio rerio Polo-like kinase 1 (Plk1) catalytic domain in complex with an extended inhibitor targeting the adaptive pocket of the enzyme.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080801

• Delayed and accelerated aging share common longevity assurance mechanisms.

  PLoS genetics 20080801

• The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation.

  Journal of Korean medical science 20080801

• Proteomic analysis of recombinant Saccharomyces cerevisiae upon iron deficiency induced via human H-ferritin production.

  Journal of microbiology and biotechnology 20080801

• Novel agents in chronic lymphocytic leukemia: efficacy and tolerability of new therapies.

  Clinical lymphoma & myeloma 20080801

• Present and prospective clinical therapeutic regimens for Alzheimer's disease.

  Neuropsychiatric disease and treatment 20080801

• Bendamustine HCL for the treatment of relapsed indolent non-Hodgkin's lymphoma.

  Therapeutics and clinical risk management 20080801

• Remarkable metal counterion effect on the internucleotide J-couplings and chemical shifts of the N-H...N hydrogen bonds in the W-C base pairs.

  The journal of physical chemistry. B 20080731

• Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation.

  Biochemistry 20080729

• Altered order of substrate binding by DNA polymerase X from African Swine Fever virus.

  Biochemistry 20080729

• Regulation of a eukaryotic gene by GTP-dependent start site selection and transcription attenuation.

  Molecular cell 20080725

• Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase.

  Journal of medicinal chemistry 20080724

• Synthesis and reactivity of the aquation product of the antitumor complex trans-[Ru(III)Cl4(indazole)2]-.

  Inorganic chemistry 20080721

• Redox state of quinone affects sensitivity of Acanthamoeba castellanii mitochondrial uncoupling protein to purine nucleotides.

  The Biochemical journal 20080715

• High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation.

  The Biochemical journal 20080715

• Levodopa therapy in a Lesch-Nyhan disease patient: pathological, biochemical, neuroimaging, and therapeutic remarks.

  Movement disorders : official journal of the Movement Disorder Society 20080715

• N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.

  Bioorganic & medicinal chemistry 20080715

• Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry.

  Bioorganic & medicinal chemistry letters 20080715

• Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations.

  Organic & biomolecular chemistry 20080707

• Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding.

  The Journal of biological chemistry 20080704

• The fate of C5' radicals of purine nucleosides under oxidative conditions.

  Journal of the American Chemical Society 20080702

• The depletion of cellular ATP by AG2034 mediates cell death or cytostasis in a hypoxanthine-dependent manner in human prostate cancer cells.

  Cancer chemotherapy and pharmacology 20080701

• Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo[a]pyrene DNA adducts.

  Journal of applied toxicology : JAT 20080701

• Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000-2005.

  Annals of the rheumatic diseases 20080701

• Decrease in factor V activity: a new adverse effect of purine analogs in inflammatory bowel diseases?

  Inflammatory bowel diseases 20080701

• Therapeutic benefit of pentostatin in severe IL-10-/- colitis.

  Inflammatory bowel diseases 20080701

• Influence of direct-fed fibrolytic enzymes on diet digestibility and ruminal activity in sheep fed a grass hay-based diet.

  Journal of animal science 20080701

• Effect of mode of birth on purine and malondialdehyde in umbilical arterial plasma in normal term newborns.

  Journal of perinatology : official journal of the California Perinatal Association 20080701

• Adenosine induces hemeoxygenase-1 expression in microglia through the activation of phosphatidylinositol 3-kinase and nuclear factor E2-related factor 2.

  Glia 20080701

• Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R).

  Cancer biology & therapy 20080701

• Synergistic antitumor efficacy of suicide/ePNP gene and 6-methylpurine 2'-deoxyriboside via Salmonella against murine tumors.

  Cancer gene therapy 20080701

• Characterization of the acute temporal changes in excisional murine cutaneous wound inflammation by screening of the wound-edge transcriptome.

  Physiological genomics 20080701

• Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens.

  Protein science : a publication of the Protein Society 20080701

• Genotoxic and cytotoxic potential of titanium dioxide (TiO2) nanoparticles on fish cells in vitro.

  Ecotoxicology (London, England) 20080701

• Mechanistic insights into the Michael addition of deoxyguanosine to catechol estrogen-3,4-quinones.

  Chemical research in toxicology 20080701

• 3'-Intercalation of a N2-dG 1R-trans-anti-benzo[c]phenanthrene DNA adduct in an iterated (CG)3 repeat.

  Chemical research in toxicology 20080701

• Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.

  Pharmacogenetics and genomics 20080701

• Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes.

  Molecular microbiology 20080701

• Influence of carbohydrate source on ruminal fermentation characteristics, performance, and microbial protein synthesis in dairy cows.

  Journal of dairy science 20080701

• A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives.

  Acta crystallographica. Section D, Biological crystallography 20080701

• Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP.

  Acta crystallographica. Section D, Biological crystallography 20080701

• Alemtuzumab for B-cell chronic lymphocytic leukemia.

  Expert review of anticancer therapy 20080701

• Purine and pyrimidine derivatives from the South China Sea gorgonian Subergorgia suberosa.

  Chemical & pharmaceutical bulletin 20080701

• Purinergic signalling and disorders of the central nervous system.

  Nature reviews. Drug discovery 20080701

• Induction of nucleoside phosphorylase in Enterobacter aerogenes and enzymatic synthesis of adenine arabinoside.

  Journal of Zhejiang University. Science. B 20080701

• Differentiation and gene flow among European populations of Leishmania infantum MON-1.

  PLoS neglected tropical diseases 20080701

• Arabidopsis 10-formyl tetrahydrofolate deformylases are essential for photorespiration.

  The Plant cell 20080701

• Mathematical modeling of folate metabolism: predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080701

• Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure.

  Environmental health perspectives 20080701

• SLC28 genes and concentrative nucleoside transporter (CNT) proteins.

  Xenobiotica; the fate of foreign compounds in biological systems 20080701

• Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins.

  Xenobiotica; the fate of foreign compounds in biological systems 20080701

• Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents.

  Archives of pharmacal research 20080701

• Bendamustine in chronic lymphocytic leukemia and refractory lymphoma.

  Seminars in hematology 20080701

• Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications.

  Journal of molecular biology 20080627

• Liquid crystalline phase of G-tetrad DNA for NMR study of detergent-solubilized proteins.

  Journal of the American Chemical Society 20080618

• Pleuromutilin derivatives having a purine ring. Part 1: new compounds with promising antibacterial activity against resistant Gram-positive pathogens.

  Bioorganic & medicinal chemistry letters 20080615

• HPLC assay with UV detection for determination of RBC purine nucleotide concentrations and application for biomarker study in vivo.

  Journal of pharmaceutical and biomedical analysis 20080609

• Targeting gene therapy for hepatocarcinoma cells with the E. coli purine nucleoside phosphorylase suicide gene system directed by a chimeric alpha-fetoprotein promoter.

  Cancer letters 20080608

• Separation of purine and pyrimidine bases by ion chromatography with direct conductivity detection.

  Journal of chromatography. A 20080606

• The dynamic structural basis of differential enhancement of conformational stability by 5'- and 3'-dangling ends in RNA.

  Biochemistry 20080603

• A single center experience of methotrexate in the treatment of Crohn's disease and ulcerative colitis: a case for subcutaneous administration.

  Journal of gastroenterology and hepatology 20080601

• Mapping two genes in the purine metabolism pathway of soybean.

  DNA sequence : the journal of DNA sequencing and mapping 20080601

• Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cells.

  Angiogenesis 20080601

• An unconditioned bone marrow transplantation in a child with purine nucleoside phosphorylase deficiency and its unique complication.

  Pediatric transplantation 20080601

• HIF-1 alpha is an essential effector for purine nucleoside-mediated neuroprotection against hypoxia in PC12 cells and primary cerebellar granule neurons.

  Journal of neurochemistry 20080601

• Mitochondrial respiratory pathways modulate nitrate sensing and nitrogen-dependent regulation of plant architecture in Nicotiana sylvestris.

  The Plant journal : for cell and molecular biology 20080601

• Prolymphocytic leukaemia of B- and T-cell subtype: a state-of-the-art paper.

  European journal of haematology 20080601

• The paradoxical relationship between serum uric acid and cardiovascular disease.

  Clinica chimica acta; international journal of clinical chemistry 20080601

• A TSC22-like motif defines a novel antiapoptotic protein family.

  FEMS yeast research 20080601

• The complete nucleotide sequence of the type 5 Helicoverpa armigera cytoplasmic polyhedrosis virus genome.

  Virus genes 20080601

• A case of serendipity*.

  Purinergic signalling 20080601

• Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes.

  Purinergic signalling 20080601

• Purinergic signalling in the subretinal space: a role in the communication between the retina and the RPE.

  Purinergic signalling 20080601

• Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism.

  Journal of biomolecular structure & dynamics 20080601

• Effect of Veillonella parvula on the antimicrobial resistance and gene expression of Streptococcus mutans grown in a dual-species biofilm.

  Oral microbiology and immunology 20080601

• Giardia lamblia: biochemical characterization of an ecto-ATPase activity.

  Experimental parasitology 20080601

• Serum urate as a predictor of clinical and radiographic progression in Parkinson disease.

  Archives of neurology 20080601

• A purine-selective nucleobase/nucleoside transporter in PK15NTD cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080601

• Characterization of nucleoside triphosphate diphosphohydrolase activity in Trichomonas gallinae and the influence of penicillin and streptomycin in extracellular nucleotide hydrolysis.

  FEMS microbiology letters 20080601

• Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery.

  The FEBS journal 20080601

• Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.

  American journal of physiology. Heart and circulatory physiology 20080601

• Suicide gene/prodrug therapy using salmonella-mediated delivery of Escherichia coli purine nucleoside phosphorylase gene and 6-methoxypurine 2'-deoxyriboside in murine mammary carcinoma 4T1 model.

  Cancer science 20080601

• Nucleoside composition of Heloderma venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601

• Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations.

  Molecular microbiology 20080601

• Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells.

  DNA repair 20080601

• Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction.

  Chemical research in toxicology 20080601

• Localization and nucleotide specificity of Blastocystis succinyl-CoA synthetase.

  Molecular microbiology 20080601

• Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry.

  Chemical research in toxicology 20080601

• Identification and characterization of a novel adenine phosphoribosyltransferase gene (ZmAPT2) from maize (Zea mays L.).

  DNA sequence : the journal of DNA sequencing and mapping 20080601

• Imaging of cell proliferation: status and prospects.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080601

• Downregulation of the Escherichia coli guaB promoter by FIS.

  Microbiology (Reading, England) 20080601

• CSMET: comparative genomic motif detection via multi-resolution phylogenetic shadowing.

  PLoS computational biology 20080601

• Novel purine nucleoside analogues for hematological malignancies.

  Recent patents on anti-cancer drug discovery 20080601

• [Ultrastructural analysis of 5' nucleotides distribution in acute myeloid leukemia subtypes].

  Zhongguo shi yan xue ye xue za zhi 20080601

• The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.

  Acta crystallographica. Section D, Biological crystallography 20080601

• FDA drug approval summary: nelarabine (Arranon) for the treatment of T-cell lymphoblastic leukemia/lymphoma.

  The oncologist 20080601

• Concepts of neural nitric oxide-mediated transmission.

  The European journal of neuroscience 20080601

• PP07: new approaches, new knowledge, new challenges in human purine and pyrimidine metabolism.

  Nucleosides, nucleotides & nucleic acids 20080601

• The diagnosis of HPRT deficiency in the 21st century.

  Nucleosides, nucleotides & nucleic acids 20080601

• Effects of allopurinol on beer-induced increases in plasma concentrations of purine bases and uridine.

  Nucleosides, nucleotides & nucleic acids 20080601

• Antioxidant status and purine bases in carotid artery plaque.

  Nucleosides, nucleotides & nucleic acids 20080601

• Purine contents of soybean-derived foods and selected Japanese vegetables and mushrooms.

  Nucleosides, nucleotides & nucleic acids 20080601

• Effect of acarbose on the increased plasma concentration of uric acid induced by sucrose ingestion.

  Nucleosides, nucleotides & nucleic acids 20080601

• Fludarabine induces differential expression of proteins in human leukemia and lymphoma cells.

  Nucleosides, nucleotides & nucleic acids 20080601

• Unusual presentation of Kelley-Seegmiller syndrome.

  Nucleosides, nucleotides & nucleic acids 20080601

• Neurotrophic effects of extracellular guanosine.

  Nucleosides, nucleotides & nucleic acids 20080601

• Molecular mechanisms of mitochondrial DNA depletion diseases caused by deficiencies in enzymes in purine and pyrimidine metabolism.

  Nucleosides, nucleotides & nucleic acids 20080601

• Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis.

  Nucleosides, nucleotides & nucleic acids 20080601

• Modulation of AMP deaminase in rat hearts subjected to ischemia and reperfusion by purine riboside.

  Nucleosides, nucleotides & nucleic acids 20080601

• Interactions of beta- and hydroxypropyl-beta-cyclodextrin with some purine alkaloids: thermodynamic study.

  Current drug discovery technologies 20080601

• Pemetrexed as second-line therapy for advanced non-small-cell lung cancer (NSCLC).

  Therapeutics and clinical risk management 20080601

• Treatment strategies in mucous membrane pemphigoid.

  Therapeutics and clinical risk management 20080601

• PP07. Proceedings of the 12th International Symposium on Purine and Pyrimidine Metabolism in Man, Chicago, Illinois, USA, June 2007.

  Nucleosides, nucleotides & nucleic acids 20080601

• Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine).

  International journal of molecular sciences 20080601

• Key labeling technologies to tackle sizeable problems in RNA structural biology.

  International journal of molecular sciences 20080601

• Mycophenolate mofetil in the treatment of lupus nephritis.

  Biologics : targets & therapy 20080601

• Comparative evaluation of some flavonoids and tocopherol acetate against the systemic toxicity induced by sulphur mustard.

  Indian journal of pharmacology 20080601

• Characterization of intestinal absorption of mizoribine mediated by concentrative nucleoside transporters in rats.

  European journal of pharmacology 20080531

• Glutamatergic and purinergic mechanisms on respiratory modulation in the caudal NTS of awake rats.

  Respiratory physiology & neurobiology 20080531

• Prediction of translation initiation sites in human mRNA sequences with AUG start codon in weak Kozak context: A neural network approach.

  Biochemical and biophysical research communications 20080516

• Cysteine-scanning analysis of putative helix XII in the YgfO xanthine permease: ILE-432 and ASN-430 are important.

  The Journal of biological chemistry 20080516

• Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells.

  Journal of cellular biochemistry 20080515

• Remote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase.

  Biophysical journal 20080515

• Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria.

  The Biochemical journal 20080515

• Human in vivo research on the vascular effects of adenosine.

  European journal of pharmacology 20080513

• Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.

  British journal of cancer 20080506

• Investigation of DNA-protein cross-link formation between lysozyme and oxanine by mass spectrometry.

  Chembiochem : a European journal of chemical biology 20080505

• Structural basis for substrate promiscuity of dCK.

  Journal of molecular biology 20080502

• IMPDH1 gene polymorphisms and association with acute rejection in renal transplant patients.

  Clinical pharmacology and therapeutics 20080501

• Adenosine: trigger and mediator of cardioprotection.

  Basic research in cardiology 20080501

• The nadA gene of Aspergillus nidulans, encoding adenine deaminase, is subject to a unique regulatory pattern.

  Fungal genetics and biology : FG & B 20080501

• Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells.

  Cellular microbiology 20080501

• Controversies in the front-line management of chronic lymphocytic leukemia.

  Leukemia research 20080501

• The separation of antagonist from agonist effects of trisubstituted purines on CaV2.2 (N-type) channels.

  Journal of neurochemistry 20080501

• A CD study of uncoupling protein-1 and its transmembrane and matrix-loop domains.

  The Biochemical journal 20080501

• Extracellular purines are biomarkers of neutrophilic airway inflammation.

  The European respiratory journal 20080501

• A critical role for ureides in dark and senescence-induced purine remobilization is unmasked in the Atxdh1 Arabidopsis mutant.

  The Plant journal : for cell and molecular biology 20080501

• Purine nucleoside phosphorylase from Pseudoalteromonas sp. Bsi590: molecular cloning, gene expression and characterization of the recombinant protein.

  Extremophiles : life under extreme conditions 20080501

• Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade.

  Biochimica et biophysica acta 20080501

• Chronic dietary L-arginine down-regulates adenosine receptor and nitric oxide synthase expression in rat heart.

  Basic & clinical pharmacology & toxicology 20080501

• Xanthine oxidoreductase in respiratory and cardiovascular disorders.

  American journal of physiology. Lung cellular and molecular physiology 20080501

• An important role of G638 in the cis-cleavage reaction of the Neurospora VS ribozyme revealed by a novel nucleotide analog incorporation method.

  RNA (New York, N.Y.) 20080501

• A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism.

  Molecular microbiology 20080501

• Effect of trimetazidine on xanthine oxidoreductase expression in rat kidney with ischemia--reperfusion injury.

  Archives of medical research 20080501

• Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae.

  Bioorganic & medicinal chemistry 20080501

• The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis.

  Molecular microbiology 20080501

• Oxidative amination of cuprated pyrimidine and purine derivatives.

  Organic letters 20080501

• Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.

  Bioorganic & medicinal chemistry letters 20080501

• Profound hypogammaglobulinemia 7 years after treatment for indolent lymphoma.

  Cancer investigation 20080501

• A detailed view on the constituents of EPs 7630.

  Planta medica 20080501

• Acid phosphatases from the liver of Labeo rohita: purification and characterization.

  Biological & pharmaceutical bulletin 20080501

• Life without RNase P.

  Nature 20080501

• Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T.

  PLoS genetics 20080501

• The electron affinities of deprotonated adenine, guanine, cytosine, uracil, and thymine.

  Nucleosides, nucleotides & nucleic acids 20080501

• Genome analysis of food grade lactic Acid-producing bacteria: from basics to applications.

  Current genomics 20080501

• 6-(2-Methoxy-benzyl-amino)purine.

  Acta crystallographica. Section E, Structure reports online 20080501

• The role of NMDA receptor antagonists in nicotine tolerance, sensitization, and physical dependence: a preclinical review.

  Yonsei medical journal 20080430

• Computational and experimental evidence for the structural preference of phenolic C-8 purine adducts.

  The journal of physical chemistry. A 20080424

• 2'-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine.

  Organic & biomolecular chemistry 20080421

• Therapeutic effects of combined treatment with ribavirin and tiazofurin on experimental autoimmune encephalomyelitis development: clinical and histopathological evaluation.

  Journal of the neurological sciences 20080415

• A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites.

  The Biochemical journal 20080415

• Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients.

  Blood 20080415

• Design and synthesis of nitrate esters of aromatic heterocyclic compounds as pharmacological preconditioning agents.

  Bioorganic & medicinal chemistry 20080415

• Structure-activity relationship for adenosine kinase from Mycobacterium tuberculosis II. Modifications to the ribofuranosyl moiety.

  Biochemical pharmacology 20080415

• Structural basis for substrate specificity in group I nucleoside hydrolases.

  Biochemistry 20080415

• Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens.

  Journal of medicinal chemistry 20080410

• Stereospecific synthesis of sugar-1-phosphates and their conversion to sugar nucleotides.

  Carbohydrate research 20080407

• Mechanisms of base selection by the Escherichia coli mispaired uracil glycosylase.

  The Journal of biological chemistry 20080404

• Reversible compartmentalization of de novo purine biosynthetic complexes in living cells.

  Science (New York, N.Y.) 20080404

• Hydroxyl radicals (*OH) are associated with titanium dioxide (TiO(2)) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells.

  Mutation research 20080402

• A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases.

  International journal of medical microbiology : IJMM 20080401

• Effect of spermine conjugation on the interaction of acridine with alternating purine-pyrimidine oligodeoxyribonucleotides studied by CD, fluorescence and absorption spectroscopies.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

• Characterization and kinetics of the major purine transporters in Aspergillus fumigatus.

  Fungal genetics and biology : FG & B 20080401

• Higher biomass accumulation by increasing phosphoribosylpyrophosphate synthetase activity in Arabidopsis thaliana and Nicotiana tabacum.

  Plant biotechnology journal 20080401

• Adenosine, through the A1 receptor, inhibits vesicular MHC class I cross-presentation by resting DC.

  Molecular immunology 20080401

• Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery.

  American journal of physiology. Lung cellular and molecular physiology 20080401

• Assessment of genotoxicity in rats treated with the antidiabetic agent, pioglitazone.

  Environmental and molecular mutagenesis 20080401

• Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP.

  Molecular pharmacology 20080401

• Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei.

  Molecular and biochemical parasitology 20080401

• The peroxisome: still a mysterious organelle.

  Histochemistry and cell biology 20080401

• Excision of the nifD element in the heterocystous cyanobacteria.

  Archives of microbiology 20080401

• Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

  Bioorganic & medicinal chemistry 20080401

• Purine alkaloids from the South China Sea gorgonian Subergorgia suberosa.

  Journal of natural products 20080401

• Comparative molecular biological analysis of membrane transport genes in organisms.

  Plant molecular biology 20080401

• A continuous assay of acetate kinase activity: measurement of inorganic phosphate release generated by hydroxylaminolysis of acetyl phosphate.

  Bioorganic chemistry 20080401

• Mechanisms of leukocyte migration across the blood-retina barrier.

  Seminars in immunopathology 20080401

• The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnover.

  Molecular microbiology 20080401

• Variation of serum uric acid levels in multiple sclerosis during relapses and immunomodulatory treatment.

  European journal of neurology 20080401

• Structural basis for recognition of Co2+ by RNA aptamers.

  The FEBS journal 20080401

• Label-free sequence-specific DNA sensing using copper-enhanced anodic stripping of purine bases at boron-doped diamond electrodes.

  Analytical chemistry 20080401

• Purine-containing cucurbitane triterpenoids from Cucurbita pepo cv dayangua.

  Phytochemistry 20080401

• SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.

  Nature genetics 20080401

• Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner.

  The Journal of general virology 20080401

• A study on the inhibition of adenosine deaminase.

  Journal of enzyme inhibition and medicinal chemistry 20080401

• Acarbose alleviates rise in plasma uric acid concentration induced by sucrose ingestion.

  International journal of clinical pharmacology and therapeutics 20080401

• Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.

  Leukemia & lymphoma 20080401

• Use of TAGVHD warnings in patients receiving purine analogue chemotherapy.

  Transfusion medicine (Oxford, England) 20080401

• Cladribine in indolent non-Hodgkin's lymphoma.

  Expert review of anticancer therapy 20080401

• [Definition and classification of hyperuricemia].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [Urate production and regulation].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [Molecular mechanisms of urate transport in renal tubules: localization and function of urate transporters].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [Idiopathic hyperuricemia with overproduction of uric acid].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [Deficiencies of hypoxanthine guanine phosphoribosyltransferase (HPRT)].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [Pathophysiology and treatment of secondary hyperuricemia].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [How do we set the standard value of serum uric acid levels?].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [AMPD genes and urate metabolism].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• [Adenine phosphoribosyltransferase deficiency and its purine metabolism].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• Genetic variants associated with arsenic susceptibility: study of purine nucleoside phosphorylase, arsenic (+3) methyltransferase, and glutathione S-transferase omega genes.

  Environmental health perspectives 20080401

• In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile.

  PLoS medicine 20080401

• Acute tumor lysis syndrome during oral fludarabine treatment for chronic lymphocytic leukemia. Role of treatment with rasburicase.

  Onkologie 20080401

• Investigations of oligonucleotide usage variance within and between prokaryotes.

  PLoS computational biology 20080401

• Beyond the guidelines in the treatment of peripheral T-cell lymphoma: new drug development.

  Journal of the National Comprehensive Cancer Network : JNCCN 20080401

• Role of phosphodiesterase 5 in synaptic plasticity and memory.

  Neuropsychiatric disease and treatment 20080401

• Alemtuzumab in the up-front setting.

  Therapeutics and clinical risk management 20080401

• Treating refractory leukemias in childhood, role of clofarabine.

  Therapeutics and clinical risk management 20080401

• 6-(2-Chloro-benzyl-amino)purinium tetra-chlorido(dimethyl sulfoxide-κO)(nitrosyl-κN)ruthenate(III) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080401

• 4-Methyl-6-phenyl-pyrimidin-2-amine.

  Acta crystallographica. Section E, Structure reports online 20080401

• Complex effects of foamy virus central purine-rich regions on viral replication.

  Virology 20080330

• A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.

  The Journal of biological chemistry 20080328

• Consequences of impaired purine recycling in dopaminergic neurons.

  Neuroscience 20080327

• Structural studies of thiamin monophosphate kinase in complex with substrates and products.

  Biochemistry 20080325

• Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays.

  Chembiochem : a European journal of chemical biology 20080325

• Still looking for the magic spot: the crystallographically defined binding site for ppGpp on RNA polymerase is unlikely to be responsible for rRNA transcription regulation.

  Journal of molecular biology 20080321

• Synthesis of novel C6-phosphonated purine nucleosides under microwave irradiation by SNAr-Arbuzov reaction.

  The Journal of organic chemistry 20080321

• The current state of serum biomarkers of hepatotoxicity.

  Toxicology 20080320

• Structural polymorphism exhibited by a homopurine.homopyrimidine sequence found at the right end of human c-jun protooncogene.

  Archives of biochemistry and biophysics 20080315

• A sensitive and specific liquid chromatography-mass spectrometry method for determination of metacavir in rat plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

• Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors.

  British journal of cancer 20080311

• Tryptophan-free human PNP reveals catalytic site interactions.

  Biochemistry 20080311

• Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues.

  FEBS letters 20080305

• MicroRNA399 is a long-distance signal for the regulation of plant phosphate homeostasis.

  The Plant journal : for cell and molecular biology 20080301

• Suppression of inflammatory and immune responses by the A(2A) adenosine receptor: an introduction.

  British journal of pharmacology 20080301

• Leishmania mexicana amazonensis: plasma membrane adenine nucleotide translocator and chemotaxis.

  Experimental parasitology 20080301

• Novel mutations of NP in two patients with purine nucleoside phosphorylase deficiency.

  Clinical biochemistry 20080301

• Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides.

  Bioorganic & medicinal chemistry 20080301

• PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes.

  Advanced drug delivery reviews 20080301

• Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death.

  DNA repair 20080301

• Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.

  Antimicrobial agents and chemotherapy 20080301

• Comprehensive and quantitative proteome profiling of the mouse liver and plasma.

  Hepatology (Baltimore, Md.) 20080301

• p53-dependent global nucleotide excision repair of cisplatin-induced intrastrand cross links in human cells.

  Mutagenesis 20080301

• Metabolism of halophilic archaea.

  Extremophiles : life under extreme conditions 20080301

• The attachment of amino fragment to purine: inner-shell structures and spectra.

  Journal of synchrotron radiation 20080301

• The energetics of rearrangement and water elimination reactions in the radiolysis of the DNA bases in aqueous solution (eaq- and *OH attack): DFT calculations.

  Radiation research 20080301

• Emerging drugs for rarer chronic lymphoid leukemias.

  Expert opinion on emerging drugs 20080301

• Novel monoclonal antibodies for the treatment of chronic lymphocytic leukemia.

  Current cancer drug targets 20080301

• The clinical spectrum of IgM-related amyloidosis: a French nationwide retrospective study of 72 patients.

  Medicine 20080301

• Structural studies of RNA/DNA polypurine tracts.

  Chemistry & biology 20080301

• High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers.

  Chemistry & biology 20080301

• Phosphorylation-independent regulation of the diguanylate cyclase WspR.

  PLoS biology 20080301

• P2 receptors in cardiovascular regulation and disease.

  Purinergic signalling 20080301

• Internalization and desensitization of adenosine receptors.

  Purinergic signalling 20080301

• Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes.

  Purinergic signalling 20080301

• Remyelination after chronic spinal cord injury is associated with proliferation of endogenous adult progenitor cells after systemic administration of guanosine.

  Purinergic signalling 20080301

• UCB Pharma research day-25 October 2007 'Glia-neuron interactions and purinergic receptors in neurological disorders'.

  Purinergic signalling 20080301

• Plasmodium-induced inflammation by uric acid.

  PLoS pathogens 20080301

• [Enhancement of GFP expression by Kozak sequence +4G in HEK293 cells].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080301

• Alcohol related changes in regulation of NMDA receptor functions.

  Current neuropharmacology 20080301

• Voltammetric Behavior of o-Nitrophenol and Damage to DNA.

  International journal of molecular sciences 20080301

• Dietary berries and ellagic acid prevent oxidative DNA damage and modulate expression of DNA repair genes.

  International journal of molecular sciences 20080301

• Alemtuzumab in the treatment of fludarabine refractory B-cell chronic lymphocytic leukemia (CLL).

  Biologics : targets & therapy 20080301

• Pitfalls, prevention, and treatment of hyperuricemia during tumor lysis syndrome in the era of rasburicase (recombinant urate oxidase).

  Biologics : targets & therapy 20080301

• A three-state model for the photophysics of guanine.

  Journal of the American Chemical Society 20080227

• Transition state structure of E. coli tRNA-specific adenosine deaminase.

  Journal of the American Chemical Society 20080227

• Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases.

  Journal of medicinal chemistry 20080227

• Rituximab-CHOP induced interstitial pneumonitis in patients with disseminated extranodal marginal zone B cell lymphoma.

  Yonsei medical journal 20080227

• Altered thermodynamics from remote mutations altering human toward bovine purine nucleoside phosphorylase.

  Biochemistry 20080226

• Remote mutations alter transition-state structure of human purine nucleoside phosphorylase.

  Biochemistry 20080226

• Second-sphere amino acids contribute to transition-state structure in bovine purine nucleoside phosphorylase.

  Biochemistry 20080226

• Substrate orientation in xanthine oxidase: crystal structure of enzyme in reaction with 2-hydroxy-6-methylpurine.

  The Journal of biological chemistry 20080222

• Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation.

  Journal of the American Chemical Society 20080220

• Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects.

  Journal of the American Chemical Society 20080220

• Can an atomic force microscope sequence DNA using a nanopore?

  Biophysical journal 20080215

• Characters of very ancient proteins.

  Biochemical and biophysical research communications 20080215

• Isolation of inhibitory RNA aptamers against severe acute respiratory syndrome (SARS) coronavirus NTPase/Helicase.

  Biochemical and biophysical research communications 20080215

• Block of inhibitory junction potentials and TREK-1 channels in murine colon by Ca2+ store-active drugs.

  The Journal of physiology 20080215

• Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

  Journal of medicinal chemistry 20080214

• Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase.

  Journal of medicinal chemistry 20080214

• Autocatalytic demetalation of a Zn(salphen) complex provoked by unprotected N-heterocycles.

  Dalton transactions (Cambridge, England : 2003) 20080214

• Studies on umami taste. Synthesis of new guanosine 5'-phosphate derivatives and their synergistic effect with monosodium glutamate.

  Journal of agricultural and food chemistry 20080213

• Antioxidant and prooxidant properties of ascorbic acid on hepatic dysfunction induced by cold ischemia/reperfusion.

  European journal of pharmacology 20080212

• Atomic detail investigation of the structure and dynamics of DNA.RNA hybrids: a molecular dynamics study.

  The journal of physical chemistry. B 20080207

• Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo.

  The Journal of nutritional biochemistry 20080201

• Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors.

  European journal of medicinal chemistry 20080201

• Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin.

  European biophysics journal : EBJ 20080201

• Purine nucleobase transport in the intraerythrocytic malaria parasite.

  International journal for parasitology 20080201

• Characterization of cellular chemical dynamics using combined microfluidic and Raman techniques.

  Analytical and bioanalytical chemistry 20080201

• P2Y1 receptors mediate inhibitory neuromuscular transmission and enteric neuronal activation in small intestine.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080201

• Fludarabine induces growth arrest and apoptosis of cytokine- or alloantigen-stimulated peripheral blood mononuclear cells, and decreases production of Th1 cytokines via inhibition of nuclear factor kappaB.

  Bone marrow transplantation 20080201

• Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides.

  Bioorganic & medicinal chemistry 20080201

• Effects of exercise and grape juice ingestion in combination on plasma concentrations of purine bases and uridine.

  Clinica chimica acta; international journal of clinical chemistry 20080201

• Pathogen resistance of transgenic tobacco plants producing caffeine.

  Phytochemistry 20080201

• Identification, biochemical characterization, and subcellular localization of allantoate amidohydrolases from Arabidopsis and soybean.

  Plant physiology 20080201

• Caffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineering.

  Phytochemistry 20080201

• Cladribine combined with high doses of arabinoside cytosine, mitoxantrone, and G-CSF (CLAG-M) is a highly effective salvage regimen in patients with refractory and relapsed acute myeloid leukemia of the poor risk: a final report of the Polish Adult Leukemia Group.

  European journal of haematology 20080201

• Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.

  Bioorganic & medicinal chemistry letters 20080201

• An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites.

  Molecular microbiology 20080201

• Fermentation characteristics and microbial growth promoted by diets including two-phase olive cake in continuous fermenters.

  Journal of animal physiology and animal nutrition 20080201

• Bulky DNA lesions induced by reactive oxygen species.

  Chemical research in toxicology 20080201

• [Adenylosuccinate lyase deficiency: an unusual cause of neonatal seizure].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20080201

• Steric block high affinity oligonucleotide analogues: a new tool for mapping RNA-protein binding sites.

  Nucleosides, nucleotides & nucleic acids 20080201

• Monte carlo simulations of site-specific radical attack to DNA bases.

  Radiation research 20080201

• Uric acid administration in patients with acute stroke: a novel approach to neuroprotection.

  Expert review of neurotherapeutics 20080201

• Nucleotide biosynthesis is critical for growth of bacteria in human blood.

  PLoS pathogens 20080201

• A purine nucleoside analogue-acyclovir [9-(2-hydroxyethoxymethyl)-9h-guanine] reversibly impairs testicular functions in mouse.

  The Journal of toxicological sciences 20080201

• The direct precursor of the pyrimidine moiety of thiamin is not urocanic acid but histidine in Saccharomyces cerevisiae.

  Journal of nutritional science and vitaminology 20080201

• Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1).

  PLoS genetics 20080201

• Review of pemetrexed in combination with cisplatin for the treatment of malignant pleural mesothelioma.

  Therapeutics and clinical risk management 20080201

• Transport of [14C]hypoxanthine by sheep choroid plexus epithelium as a monolayer in primary culture: Na+-dependent and Na+-independent uptake by the apical membrane and rapid intracellular metabolic conversion to nucleotides.

  Neuroscience letters 20080131

• Barrier-free proton transfer in the valence anion of 2'-deoxyadenosine-5'-monophosphate. II. A computational study.

  The Journal of chemical physics 20080128

• Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.

  The Journal of biological chemistry 20080125

• Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes.

  Journal of molecular biology 20080125

• L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.

  Journal of the American Chemical Society 20080123

• Fluorescence and electrochemical detection of pyrimidine/purine transversion by a ferrocenyl aminonaphthyridine derivative.

  Organic & biomolecular chemistry 20080121

• Synthesis of modified DNA by PCR with alkyne-bearing purines followed by a click reaction.

  Organic letters 20080117

• DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts.

  Journal of the American Chemical Society 20080116

• Synthesis of guanidino analogues of PMPDAP and their immunobiological activity.

  Bioorganic & medicinal chemistry 20080115

• Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells.

  Cell cycle (Georgetown, Tex.) 20080115

• The G22A polymorphism of the ADA gene and susceptibility to autism spectrum disorders.

  Journal of autism and developmental disorders 20080101

• Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat.

  Spinal cord 20080101

• Synthesis and characterization of some pyrimidine, purine, amino acid and mixed ligand complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080101

• [Kelley-Seegmiller syndrome].

  Klinische Padiatrie 20080101

• Is uric acid itself a player or a bystander in the pathophysiology of chronic heart failure?

  Medical hypotheses 20080101

• A computational study on DNA bases interactions with dinuclear tetraacetato-diaqua-dirhodium(II,II) complex.

  Journal of inorganic biochemistry 20080101

• Wavelength dependant quenching of 2,5-diphenyloxazole fluorescence by nucleotides.

  Journal of fluorescence 20080101

• Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells.

  International journal of radiation biology 20080101

• Regulation of cytokinin biosynthesis, compartmentalization and translocation.

  Journal of experimental botany 20080101

• Compartmentalization of non-adenine nucleotides in anoxic cardiac myocytes.

  Basic research in cardiology 20080101

• Chemoenzymatic synthesis and antiviral evaluation of conformationally constrained and 3'-methyl-branched carbanucleosides using both enantiomers of the same building block.

  Bioorganic & medicinal chemistry 20080101

• Association study of human MTH1 Ile45Thr polymorphism with sporadic Parkinson's disease.

  European neurology 20080101

• Guarana (Paullinia cupana var. sorbilis), an anciently consumed stimulant from the Amazon rain forest: the seeded-fruit transcriptome.

  Plant cell reports 20080101

• 5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species.

  Bioorganic & medicinal chemistry 20080101

• NF45 and NF90 in murine seminiferous epithelium: potential role in SP-10 gene transcription.

  Journal of andrology 20080101

• Purinergic signaling in the inner ear.

  Hearing research 20080101

• Mycophenolate mofetil in primary glomerulopathies.

  Kidney international 20080101

• Functional expression of the adenosine A1 receptor in rabbit lacrimal gland.

  Experimental eye research 20080101

• Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage.

  RNA (New York, N.Y.) 20080101

• Solvable models of neighbor-dependent substitution processes.

  Mathematical biosciences 20080101

• Unambiguous structural elucidation of base-modified purine nucleosides using NMR.

  Magnetic resonance in chemistry : MRC 20080101

• Activation of adenosine 2A receptors preserves structure and function of podocytes.

  Journal of the American Society of Nephrology : JASN 20080101

• Prediction of elution bandwidth for purine compounds by a retention model in reversed-phase HPLC with linear-gradient elution.

  Journal of separation science 20080101

• Purine sensing by riboswitches.

  Biology of the cell 20080101

• Paracrinicity: the story of 30 years of cellular pituitary crosstalk.

  Journal of neuroendocrinology 20080101

• Studies on the reactivity of organometallic Ru-, Rh- and Os-pta complexes with DNA model compounds.

  Journal of inorganic biochemistry 20080101

• Interactions between barley grain processing and source of supplemental dietary fat on nitrogen metabolism and urea-nitrogen recycling in dairy cows.

  Journal of dairy science 20080101

• Evaluation of nitrogen utilization and the effects of monensin in dairy cows fed brown midrib corn silage.

  Journal of dairy science 20080101

• High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae.

  Genome biology 20080101

• Specificity of DNA-binding by the FAX-1 and NHR-67 nuclear receptors of Caenorhabditis elegans is partially mediated via a subclass-specific P-box residue.

  BMC molecular biology 20080101

• Using 454 technology for long-PCR based sequencing of the complete mitochondrial genome from single Haemonchus contortus (Nematoda).

  BMC genomics 20080101

• LTRharvest, an efficient and flexible software for de novo detection of LTR retrotransposons.

  BMC bioinformatics 20080101

• Substrate specificity of new methyl-directed DNA endonuclease GlaI.

  BMC molecular biology 20080101

• The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors.

  BMC evolutionary biology 20080101

• rosy Function is required for juvenile hormone effects in Drosophila melanogaster.

  Genetics 20080101

• Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity.

  Genome biology 20080101

• Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model.

  BMC microbiology 20080101

• The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs.

  Current medicinal chemistry 20080101

• Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.

  Molecular cancer 20080101

• Effects of a supplement designed to increase ATP levels on muscle strength, power output, and endurance.

  Journal of the International Society of Sports Nutrition 20080101

• Antimicrobial properties of milkfat globule membrane fractions.

  Journal of food protection 20080101

• Early and transient reverse transcription during primary deltaretroviral infection of sheep.

  Retrovirology 20080101

• Equilibrium model selection: dTTP induced R1 dimerization.

  BMC systems biology 20080101

• Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia.

  BMC genomics 20080101

• Multiple strand displacement amplification of mitochondrial DNA from clinical samples.

  BMC medical genetics 20080101

• Wound healing in patients with cancer.

  Eplasty 20080101

• [Nephrolithiasis in patients with intestinal diseases].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101

• Ligand-induced sequestering of branchpoint sequence allows conditional control of splicing.

  BMC molecular biology 20080101

• Using a logical model to predict the growth of yeast.

  BMC bioinformatics 20080101

• Proteomic analysis of the secretome of Leishmania donovani.

  Genome biology 20080101

• Orphan SelD proteins and selenium-dependent molybdenum hydroxylases.

  Biology direct 20080101

• Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna.

  Genome biology 20080101

• 6th international symposium on retroviral nucleocapsid.

  Retrovirology 20080101

• Novel methodology for construction and pruning of quasi-median networks.

  BMC bioinformatics 20080101

• Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis.

  BMC systems biology 20080101

• The combination of clofarabine and cytarabine in pediatric relapsed acute lymphoblastic leukemia: a case report.

  Chemotherapy 20080101

• Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia.

  BMC microbiology 20080101

• Spontaneous DNA repair increases during hemodialysis.

  Nephron. Clinical practice 20080101

• [The pathogenetic role of the serotonin-histamine-cyclic nucleotide system in ulcerogenesis].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20080101

• [Outpatient diagnostics of the initial stage of essential hypertension].

  Klinicheskaia meditsina 20080101

• Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks.

  Genome biology 20080101

• Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription.

  Journal of inflammation (London, England) 20080101

• Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo.

  PloS one 20080101

• Endogenous retroviruses of the chicken genome.

  Biology direct 20080101

• Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.

  Molecular systems biology 20080101

• Antiparasitic chemotherapy: tinkering with the purine salvage pathway.

  Advances in experimental medicine and biology 20080101

• Purine and pyrimidine metabolism in Leishmania.

  Advances in experimental medicine and biology 20080101

• Computational evaluation of TIS annotation for prokaryotic genomes.

  BMC bioinformatics 20080101

• Gene targeting in adult rhesus macaque fibroblasts.

  BMC biotechnology 20080101

• par genes in Mycobacterium bovis and Mycobacterium smegmatis are arranged in an operon transcribed from 'SigGC' promoters.

  BMC microbiology 20080101

• Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): generation by alternative translation initiation and mRNA splicing.

  BMC molecular biology 20080101

• [The treatment of Waldenström macroglobulinemia and the therapy of diseases caused by monoclonal IgM gammaglobulin].

  Vnitrni lekarstvi 20080101

• Current developments in the synthesis and biological activity of aza-C-nucleosides: immucillins and related compounds.

  Current medicinal chemistry 20080101

• OppA, the ecto-ATPase of Mycoplasma hominis induces ATP release and cell death in HeLa cells.

  BMC microbiology 20080101

• Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex.

  BMC genomics 20080101

• Polymorphisms of Glutathione S-transferases Omega-1 among ethnic populations in China.

  BMC genetics 20080101

• Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling.

  Genome biology 20080101

• Prodrug converting enzyme gene delivery by L. monocytogenes.

  BMC cancer 20080101

• Significance analysis of microarray for relative quantitation of LC/MS data in proteomics.

  BMC bioinformatics 20080101

• Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs.

  Metal-based drugs 20080101

• Novel therapies for anti-neutrophil cytoplasmic antibody-associated vasculitis.

  Drugs 20080101

• Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics.

  BMC plant biology 20080101

• High-resolution study of nuclear magnetic relaxation dispersion of purine nucleotides: effects of spin-spin coupling.

  Solid state nuclear magnetic resonance 20080101

• Regulation of 5'-adenosine monophosphate deaminase in the freeze tolerant wood frog, Rana sylvatica.

  BMC biochemistry 20080101

• Arsenic-based antineoplastic drugs and their mechanisms of action.

  Metal-based drugs 20080101

• A novel splice-site mutation of TULP1 underlies severe early-onset retinitis pigmentosa in a consanguineous Israeli Muslim Arab family.

  Molecular vision 20080101

• A mathematical model of glutathione metabolism.

  Theoretical biology & medical modelling 20080101

• Expression analysis of G Protein-Coupled Receptors in mouse macrophages.

  Immunome research 20080101

• The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase.

  BMC biochemistry 20080101

• Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction.

  PloS one 20080101

• Comparative analysis of sequence features involved in the recognition of tandem splice sites.

  BMC genomics 20080101

• The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis.

  BMC evolutionary biology 20080101

• Reconstructing networks of pathways via significance analysis of their intersections.

  BMC bioinformatics 20080101

• Anti-inflammatory preconditioning by agonists of adenosine A1 receptor.

  PloS one 20080101

• Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor.

  PloS one 20080101

• Effects of subminimum inhibitory concentrations of antibiotics on the Pasteurella multocida proteome: a systems approach.

  Comparative and functional genomics 20080101

• Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites.

  BMC bioinformatics 20080101

• Microsatellite evolution: Mutations, sequence variation, and homoplasy in the hypervariable avian microsatellite locus HrU10.

  BMC evolutionary biology 20080101

• Cytotoxic nucleoside analogues: different strategies to improve their clinical efficacy.

  Current medicinal chemistry 20080101

• Impact of point-mutations on the hybridization affinity of surface-bound DNA/DNA and RNA/DNA oligonucleotide-duplexes: comparison of single base mismatches and base bulges.

  BMC biotechnology 20080101

• Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs.

  PloS one 20080101

• The BsaHI restriction-modification system: cloning, sequencing and analysis of conserved motifs.

  BMC molecular biology 20080101

• PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression.

  BMC genomics 20080101

• Genomic analysis of post-mating changes in the honey bee queen (Apis mellifera).

  BMC genomics 20080101

• Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules.

  Source code for biology and medicine 20080101

• Trait-trait dynamic interaction: 2D-trait eQTL mapping for genetic variation study.

  BMC genomics 20080101

• Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis.

  PloS one 20080101

• The binary protein interactome of Treponema pallidum--the syphilis spirochete.

  PloS one 20080101

• Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.

  PloS one 20080101

• Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species.

  BMC genomics 20080101

• Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts.

  Critical care (London, England) 20080101

• Genome-wide survey of allele-specific splicing in humans.

  BMC genomics 20080101

• Botulinum toxin: treatment of self-mutilation in patients with Lesch-Nyhan syndrome.

  Clinical neuropharmacology 20080101

• 'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus.

  BMC biology 20080101

• Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor.

  PloS one 20080101

• Analysis of the EIAV Rev-responsive element (RRE) reveals a conserved RNA motif required for high affinity Rev binding in both HIV-1 and EIAV.

  PloS one 20080101

• Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos.

  Plant physiology and biochemistry : PPB 20080101

• Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order.

  Comparative and functional genomics 20080101

• GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors.

  BMC bioinformatics 20080101

• Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53.

  Proteome science 20080101

• Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways.

  AIDS research and therapy 20080101

• The highest-copy repeats are methylated in the small genome of the early divergent vascular plant Selaginella moellendorffii.

  BMC genomics 20080101

• Genomic mid-range inhomogeneity correlates with an abundance of RNA secondary structures.

  BMC genomics 20080101

• Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.

  PloS one 20080101

• Maintenance metabolism and carbon fluxes in Bacillus species.

  Microbial cell factories 20080101

• A naturally occurring omega current in a Kv3 family potassium channel from a platyhelminth.

  BMC neuroscience 20080101

• Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivo.

  PloS one 20080101

• A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge.

  PloS one 20080101

• Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog.

  BMC biochemistry 20080101

• The role of upstream sequences in selecting the reading frame on tmRNA.

  BMC biology 20080101

• Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia.

  Biology direct 20080101

• A cryptic promoter in the first exon of the SPG4 gene directs the synthesis of the 60-kDa spastin isoform.

  BMC biology 20080101

• Investigating selection on viruses: a statistical alignment approach.

  BMC bioinformatics 20080101

• Articulation of three core metabolic processes in Arabidopsis: fatty acid biosynthesis, leucine catabolism and starch metabolism.

  BMC plant biology 20080101

• Thermodynamics of binding of divalent magnesium and manganese to uridine phosphates: implications for diabetes-related hypomagnesaemia and carbohydrate biocatalysis.

  Chemistry Central journal 20080101

• Global regulation of nucleotide biosynthetic genes by c-Myc.

  PloS one 20080101

• Genome holography: deciphering function-form motifs from gene expression data.

  PloS one 20080101

• Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways.

  Journal of biomedicine & biotechnology 20080101

• The transcriptional program underlying the physiology of clostridial sporulation.

  Genome biology 20080101

• Allantoin as a marker of oxidative stress in human erythrocytes.

  Clinical chemistry and laboratory medicine 20080101

• A new perspective on phylogeny and evolution of tetraodontiform fishes (Pisces: Acanthopterygii) based on whole mitochondrial genome sequences: basal ecological diversification?

  BMC evolutionary biology 20080101

• Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications.

  BMC structural biology 20080101

• Growth rate regulated genes and their wide involvement in the Lactococcus lactis stress responses.

  BMC genomics 20080101

• Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study.

  PloS one 20080101

• Multiple functions for ORF75c in murid herpesvirus-4 infection.

  PloS one 20080101

• Characterization of new IS elements and studies of their dispersion in two subspecies of Leifsonia xyli.

  BMC microbiology 20080101

• Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.

  BMC genomics 20080101

• Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons.

  Progress in brain research 20080101

• Overexpression of the riboflavin biosynthetic pathway in Pichia pastoris.

  Microbial cell factories 20080101

• Remodeling of the Streptococcus agalactiae transcriptome in response to growth temperature.

  PloS one 20080101

• ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia.

  PloS one 20080101

• Conserved upstream open reading frames in higher plants.

  BMC genomics 20080101

• Regulation of cancer progression by inhibition of angiogenesis and induction of apoptosis.

  Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20080101

• Proteomic approaches in understanding action mechanisms of metal-based anticancer drugs.

  Metal-based drugs 20080101

• Enzymatic synthesis of multiple spin-labeled DNA.

  Angewandte Chemie (International ed. in English) 20080101

• Differential control of Zap1-regulated genes in response to zinc deficiency in Saccharomyces cerevisiae.

  BMC genomics 20080101

• Cytotoxic and genotoxic effects of methotrexate in germ cells of male Swiss mice.

  Mutation research 20080101

• In vivo analysis of Caenorhabditis elegans noncoding RNA promoter motifs.

  BMC molecular biology 20080101

• The evolutionary origin of the Runx/CBFbeta transcription factors--studies of the most basal metazoans.

  BMC evolutionary biology 20080101

• Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.

  Molecular systems biology 20080101

• Complexes of Cu(II) ions and noncovalent interactions in systems with L-aspartic acid and cytidine-5'-monophosphate.

  Bioinorganic chemistry and applications 20080101

• P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis.

  Journal of neuroinflammation 20080101

• Characterization of expressed sequence tags from a full-length enriched cDNA library of Cryptomeria japonica male strobili.

  BMC genomics 20080101

• Novel therapies in genitourinary cancer: an update.

  Journal of hematology & oncology 20080101

• Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562.

  BMC genomics 20080101

• Successful long-term monotherapy with rituximab in a patient with chronic lymphocytic leukemia of the B-cell-lineage: a case report.

  Journal of medical case reports 20080101

• Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate.

  BMC genomics 20080101

• Streptococcus pneumoniae early response genes to human lung epithelial cells.

  BMC research notes 20080101

• Integrative analyses of genetic variation in enzyme activities of primary carbohydrate metabolism reveal distinct modes of regulation in Arabidopsis thaliana.

  Genome biology 20080101

• A DNA and morphology based phylogenetic framework of the ant genus Lasius with hypotheses for the evolution of social parasitism and fungiculture.

  BMC evolutionary biology 20080101

• Origin of co-expression patterns in E. coli and S. cerevisiae emerging from reverse engineering algorithms.

  PloS one 20080101

• Mizoribine treatment of young patients with severe lupus nephritis: a clinicopathologic study by the tohoku pediatric study group.

  Nephron. Clinical practice 20080101

• A translation initiation element specific to mRNAs with very short 5'UTR that also regulates transcription.

  PloS one 20080101

• Extensive adaptive changes occur in the transcriptome of Streptococcus agalactiae (group B streptococcus) in response to incubation with human blood.

  PloS one 20080101

• Global self-organization of the cellular metabolic structure.

  PloS one 20080101

• Longer first introns are a general property of eukaryotic gene structure.

  PloS one 20080101

• Triplex glue by synthesizing conjugated flexible intercalators.

  Nucleic acids symposium series (2004) 20080101

• Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker.

  Nucleic acids symposium series (2004) 20080101

• Repair of DNA-protein crosslink damage: coordinated actions of nucleotide excision repair and homologous recombination.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and properties of (alpha-P-borano)-nucleoside 5'-triphosphate analogues as potential antiviral agents.

  Nucleic acids symposium series (2004) 20080101

• The interaction between the purine motif triplex and the triplex DNA-binding domain of Saccharomyces cerevisiae Stm1 protein.

  Nucleic acids symposium series (2004) 20080101

• Efficient preparation of xanthine-containing oligodeoxynucleotide from oxanine-containing oligodeoxynucleotide, catalyzed by N alpha-acetyl-L-histidine.

  Nucleic acids symposium series (2004) 20080101

• Reactivity of oxanine: efficient fabrication of DNA microarray by using oxanine-containing DNA oligomer as probe molecule.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and some transformation of acyclic nucleotide phosphonate analogues with triple bond.

  Nucleic acids symposium series (2004) 20080101

• Coupled biocatalysts applied to the synthesis of nucleosides.

  Nucleic acids symposium series (2004) 20080101

• Regioselective glycosylation of 7-azapteridines and conversion of the 7-azapteridine nucleosides into 6-azapurine nucleosides.

  Nucleic acids symposium series (2004) 20080101

• Design and synthesis of 1-(beta-D-ribofuranosyl)imidazo[4,5-c]pyrazoles as 5:5 bicyclic analogs of purine nucleosides.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.

  Nucleic acids symposium series (2004) 20080101

• The novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations.

  Nucleic acids symposium series (2004) 20080101

• Synthesis of novel cyclopropyl nucleoside analogues as potential antiherpetic agent.

  Nucleic acids symposium series (2004) 20080101

• Hetero-expanded purine nucleosides. Design, synthesis and preliminary biological activity.

  Nucleic acids symposium series (2004) 20080101

• Synthesis of 2-chloro-N6-substituted-4'-thioadenosine-5'-N, N-dialkyluronamides as potent and selective A3 adenosine receptor antagonists.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and biological evaluation of 5''-iodoneplanocin A and its analogues.

  Nucleic acids symposium series (2004) 20080101

• 9-Deazaguanine derivatives: synthesis and inhibitory properties as multi-substrate analogue inhibitors of mammalian PNPs.

  Nucleic acids symposium series (2004) 20080101

• Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors.

  Nucleic acids symposium series (2004) 20080101

• On the analysis of fluorimetric titration curves of purine nucleoside phosphorylase.

  Nucleic acids symposium series (2004) 20080101

• Gene expression variation to predict 10-year survival in lymph-node-negative breast cancer.

  BMC cancer 20080101

• A random shRNA-encoding library for phenotypic selection and hit-optimization.

  PloS one 20080101

• Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda.

  Journal of translational medicine 20080101

• Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii.

  BMC biotechnology 20080101

• Automatic detection of exonic splicing enhancers (ESEs) using SVMs.

  BMC bioinformatics 20080101

• Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.).

  BMC pharmacology 20080101

• [The influence of purine nucleotides and adenosine on bioelectrical activity of bat (Pipistrellus nathusii) heart].

  Kardiologiia 20080101

• Assessment of Hematological and Biochemical parameters with extended D-Ribose ingestion.

  Journal of the International Society of Sports Nutrition 20080101

• Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia.

  BMC genomics 20080101

• Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover.

  Molecular cancer 20080101

• Mathematical models of folate-mediated one-carbon metabolism.

  Vitamins and hormones 20080101

• Regulation of human dihydrofolate reductase activity and expression.

  Vitamins and hormones 20080101

• Mitochondrial methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetases.

  Vitamins and hormones 20080101

• [Mitochondrial uncoupling proteins: regulation and physiological role].

  Postepy biochemii 20080101

• Epigenetic regulation of genomes: nutrient-specific modulation of genetic networks in bovine cells.

  Developments in biologicals 20080101

• The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile.

  Nutrition journal 20080101

• Bench-to-bedside review: adenosine receptors--promising targets in acute lung injury?

  Critical care (London, England) 20080101

• The unfoldomics decade: an update on intrinsically disordered proteins.

  BMC genomics 20080101

• Gene and pathway identification with Lp penalized Bayesian logistic regression.

  BMC bioinformatics 20080101

• Performance of mitochondrial DNA mutations detecting early stage cancer.

  BMC cancer 20080101

• Triamcinolone acetonide and anecortave acetate do not stimulate uveal melanoma cell growth.

  Molecular vision 20080101

• Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes.

  BMC developmental biology 20080101

• Effect of nucleoside and nucleotide reverse transcriptase inhibitors of HIV on endogenous nucleotide pools.

  Antiviral therapy 20080101

• Ubiquitous water-soluble molecules in aquatic plant exudates determine specific insect attraction.

  PloS one 20080101

• ITS-2 secondary structures and phylogeny of Anopheles culicifacies species.

  Bioinformation 20080101

• RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes.

  BMC genomics 20080101

• Head-to-head right-handed cross-links of the antitumor-active bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) unit with the dinucleotides d(GpA) and d(ApG).

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Toxicogenomic response of Pseudomonas aeruginosa to ortho-phenylphenol.

  BMC genomics 20080101

• The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation.

  Critical care (London, England) 20080101

• Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines.

  Current medicinal chemistry 20080101

• Structural bioinformatics study of PNP from Listeria monocytogenes.

  Protein and peptide letters 20080101

• Computational identification of three-way junctions in folded RNAs: a case study in Arabidopsis.

  In silico biology 20080101

• Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis.

  BMC genomics 20080101

• Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift?

  Biology direct 20080101

• Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes.

  Molecular cancer 20080101

• Developments in the scientific and clinical understanding of gout.

  Arthritis research & therapy 20080101

• Dramatic down-regulation of oxidoreductases in human hepatocellular carcinoma hepG2 cells: proteomics and gene ontology unveiling new frontiers in cancer enzymology.

  Proteome science 20080101

• Significant association of SREBP-2 genetic polymorphisms with avascular necrosis in the Korean population.

  BMC medical genetics 20080101

• Protein functional surfaces: global shape matching and local spatial alignments of ligand binding sites.

  BMC structural biology 20080101

• Model-guided design of ligand-regulated RNAi for programmable control of gene expression.

  Molecular systems biology 20080101

• Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves.

  Frontiers in neuroengineering 20080101

• Use of fludarabine-containing chemotherapeutic regimen results in durable complete remission of subcutaneous panniculitis-like T-cell lymphoma.

  American journal of clinical dermatology 20080101

• Non coding extremities of the seven influenza virus type C vRNA segments: effect on transcription and replication by the type C and type A polymerase complexes.

  Virology journal 20080101

• Lesch-Nyhan syndrome: a case report.

  Journal of the Indian Society of Pedodontics and Preventive Dentistry 20080101

• The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.

  PloS one 20080101

• Sequence specificity of BAL 31 nuclease for ssDNA revealed by synthetic oligomer substrates containing homopolymeric guanine tracts.

  PloS one 20080101

• Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane.

  PloS one 20080101

• Hierarchical structure of cascade of primary and secondary periodicities in Fourier power spectrum of alphoid higher order repeats.

  BMC bioinformatics 20080101

• mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.

  BMC genomics 20080101

• Purine metabolism in heart failure: oxidant biology and therapeutic indications.

  Congestive heart failure (Greenwich, Conn.) 20080101

• Guanylyl cyclase sees the light.

  Journal of biology 20080101

• Synthesis of DNA strands site-specifically damaged by c8-arylamine purine adducts and effects on various DNA polymerases.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans.

  Genome biology 20080101

• Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin.

  PloS one 20080101

• Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis.

  PloS one 20080101

• Architecture of thermal adaptation in an Exiguobacterium sibiricum strain isolated from 3 million year old permafrost: a genome and transcriptome approach.

  BMC genomics 20080101

• Collision induced dissociation studies of alkali metal adducts of tetracyclines and antiviral agents by electrospray ionization, hydrogen/deuterium exchange and multiple stage mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20080101

• Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.

  Reproductive biology and endocrinology : RB&E 20080101

• Prediction of specificity-determining residues for small-molecule kinase inhibitors.

  BMC bioinformatics 20080101

• Recent CR1 non-LTR retrotransposon activity in coscoroba reveals an insertion site preference.

  BMC genomics 20080101

• Genome-wide transcriptional response of an avian pathogenic Escherichia coli (APEC) pst mutant.

  BMC genomics 20080101

• Properties and distribution of pure GA-sequences of mammalian genomes.

  PloS one 20080101

• [Monitoring of nutrition of the population of Chuvashia, in connection with prevalence of ischemic illness of heart].

  Voprosy pitaniia 20080101

• Aqueous fish extract increases survival in the mouse model of cytostatic toxicity.

  Journal of experimental & clinical cancer research : CR 20080101

• HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels.

  Retrovirology 20080101

• Assessment of expression of selected Bcl-2 family proteins in lymphoid infiltration in patients with B-cell chronic lymphocytic leukaemia treated with nucleoside analogues.

  Folia histochemica et cytobiologica 20080101

• Macronuclear genome structure of the ciliate Nyctotherus ovalis: single-gene chromosomes and tiny introns.

  BMC genomics 20080101

• Two evolutionarily conserved sequence elements for Peg3/Usp29 transcription.

  BMC molecular biology 20080101

• Small molecules ATP-competitive inhibitors of FLT3: a chemical overview.

  Current medicinal chemistry 20080101

• The role of cytokines in sleep regulation.

  Current pharmaceutical design 20080101

• [Influence of ADP-ribose, AMP and adenosine on bioelectric activity of hibernating ground squirrel atrium and papillary muscle].

  Kardiologiia 20080101

• Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications.

  BMC genomics 20080101

• Phylogenetic analysis of the non-structural (NS) gene of influenza A viruses isolated from mallards in Northern Europe in 2005.

  Virology journal 20080101

• Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study.

  Respiratory research 20080101

• Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy.

  Genome biology 20080101

• DISCLOSE : DISsection of CLusters Obtained by SEries of transcriptome data using functional annotations and putative transcription factor binding sites.

  BMC bioinformatics 20080101

• Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code.

  Biology direct 20080101

• Paraneoplastic vasculitis associated with hairy cell leukemia.

  Prague medical report 20080101

• Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease.

  BMC genomics 20080101

• Arabidopsis eIF2alpha kinase GCN2 is essential for growth in stress conditions and is activated by wounding.

  BMC plant biology 20080101

• Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats.

  Molecular pain 20080101

• Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer.

  BMC cancer 20080101

• The effect of preservation solutions UW and EC on purine concentration in rat kidney.

  Annales Academiae Medicae Stetinensis 20080101

• Antitumor activity of 6-(cyclohexylamino)-1, 3-dimethyl-5(2-pyridyl)furo[2,3-d]pyrimidine-2,4(1H,3H)-dione and Its Ti(IV), Zn(II), Fe(III), and Pd(II) complexes on K562 and Jurkat cell lines.

  Bioinorganic chemistry and applications 20080101

• Purine release: a protective signaling mechanism of the mitochondrial permeability transition pore in ischemia.

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

• Molecular docking studies on DMDP derivatives as human DHFR inhibitors.

  Bioinformation 20080101

• [Role of acute purine exchange disorders in pathogenesis of metabolism following cryolysis of portal vein].

  Voprosy onkologii 20080101

• [Purine nucleoside phosphorylase inhibitors and their clinical significance].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101

• New pathways for alimentary mucositis.

  Journal of oncology 20080101

• Label-free electrical quantification of the dielectrophoretic response of DNA.

  PMC biophysics 20080101

• New data integrating multitargeted antifolates into treatment of first-line and relapsed non-small-cell lung cancer.

  Clinical lung cancer 20080101

• Two- and three-dimensional quantitative structure-activity relationships studies on a series of liver x receptor ligands.

  The open medicinal chemistry journal 20080101

• Butyrate induced cell cycle arrest in bovine cells through targeting gene expression relevant to DNA replication apparatus.

  Gene regulation and systems biology 20080101

• Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.

  Gene regulation and systems biology 20080101

• Using a seed-network to query multiple large-scale gene expression datasets from the developing retina in order to identify and prioritize experimental targets.

  Bioinformatics and biology insights 20080101

• Folate deficiency followed by ionizing radiation perturbs hepatic dihydrofolate reducatse activity.

  BioFactors (Oxford, England) 20080101

• New and emerging trends in the treatment of atopic dermatitis.

  Patient preference and adherence 20080101

• Synthesis and evaluation of L-glutamic Acid analogs as potential anticancer agents.

  Indian journal of pharmaceutical sciences 20080101

• Screwworms, Cochliomyia hominivorax, reared for mass release do not carry and spread foot-and-mouth disease virus and classical swine fever virus.

  Journal of insect science (Online) 20080101

• Modulation of IL-4 level by fludarabine and its relation to apoptosis in chronic B-cell lymphocytic leukemia.

  The Egyptian journal of immunology 20080101

• Doxofyllinium tetra-chloridoanti-monate(III) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Ethyl 3-(4-fluoro-phen-yl)-6-methyl-4-oxo-2-(1-cyclohexylamino)-3,4-dihydro-furo[2,3-d]pyrimidine-5-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20080101

• 7-(1,3-Dioxolan-2-ylmeth-yl)-1,3-di-methyl-purine-2,6(1H,3H)-dione trichloro-acetic acid solvate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Review: mitochondrial defects in breast cancer.

  Clinical medicine. Oncology 20080101

• Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset.

  Clinical medicine. Oncology 20080101

• Modelling purine derivative excretion in dairy goats: endogenous excretion and the relationship between duodenal input and urinary output.

  Animal : an international journal of animal bioscience 20080101

• Fluorinated alcohol mediated displacement of the C10 acetoxy group of benzo[a]pyrene-7,8,9,10-tetrahydrotetraol tetraacetates: a new route to diol epoxide-deoxyguanosine adducts.

  The Journal of organic chemistry 20071221

• Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA).

  Journal of the American Chemical Society 20071219

• Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity.

  Journal of the American Chemical Society 20071219

• Sequence-specific oxidative base modifications in hypoxia-inducible genes.

  Free radical biology & medicine 20071215

• Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-beta-D-erythropentofuranosyl)-pyrimido[1,2-alpha]purine-10(3H)-one, in the rat.

  The Journal of biological chemistry 20071214

• The first direct C-H arylation of purine nucleosides.

  Chemical communications (Cambridge, England) 20071207

• Crystal structures of human and murine deoxyribonucleotidases: insights into recognition of substrates and nucleotide analogues.

  Biochemistry 20071204

• Xanthine urolithiasis in a cat: a case report and evaluation of a candidate gene for xanthine dehydrogenase.

  Journal of feline medicine and surgery 20071201

• Key role of uridine kinase and uridine phosphorylase in the homeostatic regulation of purine and pyrimidine salvage in brain.

  Neurochemistry international 20071201

• Acute hypoxia and reoxygenation-induced DNA oxidation in human mononuclear blood cells.

  Mutation research 20071201

• Conformations of flanking bases in HIV-1 RNA DIS kissing complexes studied by molecular dynamics.

  Biophysical journal 20071201

• Tryptophan, adenosine, neurodegeneration and neuroprotection.

  Metabolic brain disease 20071201

• Enzymes as a special class of therapeutic target: clinical drugs and modes of action.

  Current opinion in structural biology 20071201

• Recent progress in the management of chronic lymphocytic leukemia.

  Cancer treatment reviews 20071201

• Towards generating caffeine-free tea by metabolic engineering.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20071201

• A natural antisense transcript of the Petunia hybrida Sho gene suggests a role for an antisense mechanism in cytokinin regulation.

  The Plant journal : for cell and molecular biology 20071201

• Effects of fructose-1,6-diphosphate on endo- and myocardial purine metabolism during coronary artery bypass grafting surgery.

  The Journal of cardiovascular surgery 20071201

• Molecular dynamics simulations and their application to four-stranded DNA.

  Methods (San Diego, Calif.) 20071201

• Mutational analysis of Arabidopsis thaliana plant uncoupling mitochondrial protein.

  Biochimica et biophysica acta 20071201

• The 2,6-disubstituted purine reversine induces growth arrest and polyploidy in human cancer cells.

  International journal of oncology 20071201

• Differential effects of in vitro zinc treatment on gene expression in peripheral blood mononuclear cells derived from young and elderly individuals.

  Rejuvenation research 20071201

• The N-terminal domain of 2',3'-cyclic nucleotide 3'-phosphodiesterase harbors a GTP/ATP binding site.

  Chemical biology & drug design 20071201

• Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. A new model for substrate interactions at a dinuclear cocatalytic Zn site.

  Biochimica et biophysica acta 20071201

• Synthesis, antimicrobial and antineoplastic activities for agelasine and agelasimine analogs with a beta-cyclocitral derived substituent.

  Archiv der Pharmazie 20071201

• Adenosine-induced complete heart block: not so transient.

  Emergency medicine Australasia : EMA 20071201

• Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia?

  Journal of clinical pharmacy and therapeutics 20071201

• Glycine accumulation is toxic for the cyanobacterium Synechocystis sp. strain PCC 6803, but can be compensated by supplementation with magnesium ions.

  FEMS microbiology letters 20071201

• Infliximab therapy for pediatric Crohn's disease.

  Expert opinion on biological therapy 20071201

• Interaction between mercaptopurine and milk.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20071201

• Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin.

  Microbiology (Reading, England) 20071201

• Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20071201

• Nursing guidelines for managing infections in patients with chronic lymphocytic leukemia.

  Clinical journal of oncology nursing 20071201

• Bacterial protein meal in diets for pigs and minks: comparative studies on protein turnover rate and urinary excretion of purine base derivatives.

  Archives of animal nutrition 20071201

• Statistical analysis of effects of testosterone on purine metabolism in rat liver.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071201

• Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine.

  Seminars in oncology 20071201

• Mycosis fungoides: pathophysiology and emerging therapies.

  Seminars in oncology 20071201

• Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.

  Seminars in oncology 20071201

• Clinical management of T-cell malignancies: current perspectives, key issues, and emerging therapies.

  Seminars in oncology 20071201

• Forodesine treatment and post-transplant graft-versus-host disease in two patients with acute leukemia: facilitation of graft-versus-leukemia effect?

  Seminars in oncology 20071201

• Pharmacology and mechanism of action of forodesine, a T-cell targeted agent.

  Seminars in oncology 20071201

• Therapeutic experience of Bing-Neel Syndrome associated with Waldenstrom's macroglobulinemia.

  Journal of Korean medical science 20071201

• Conserved regulation of MAP kinase expression by PUF RNA-binding proteins.

  PLoS genetics 20071201

• Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.

  Therapeutics and clinical risk management 20071201

• Development of the anti-VEGF aptamer to a therapeutic agent for clinical ophthalmology.

  Clinical ophthalmology (Auckland, N.Z.) 20071201

• Mechanism of direct conversion between C8 adducts and N7 adducts in carcinogenic reactions of arylnitrenium ions with purine nucleosides: a theoretical study.

  The journal of physical chemistry. B 20071129

• Long-range electron and hole transport through DNA with tethered cyclometalated iridium(III) complexes.

  Journal of the American Chemical Society 20071128

• Mutational analysis of the purine riboswitch aptamer domain.

  Biochemistry 20071120

• Novel subsets of the Arabidopsis plasmalemma phosphoproteome identify phosphorylation sites in secondary active transporters.

  Biochemical and biophysical research communications 20071116

• Synthesis, biological activity, and SAR of antimycobacterial 2- and 8-substituted 6-(2-furyl)-9-(p-methoxybenzyl)purines.

  Bioorganic & medicinal chemistry 20071115

• The role of rituximab in combination with pentostatin or cladribine for the treatment of recurrent/refractory hairy cell leukemia.

  Cancer 20071115

• Effect of the Cdk-inhibitor roscovitine on mouse hematopoietic progenitors in vivo and in vitro.

  Cancer chemotherapy and pharmacology 20071101

• Density functional theory studies on tautomeric stability and infrared and Raman spectra of some purine derivatives.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071101

• Selective guanosine binding and cytotoxicity of a benzimidazole derived dinickel complex.

  Journal of inorganic biochemistry 20071101

• Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons.

  Glia 20071101

• Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20071101

• An immunocompetent murine model for oncolysis with an armed and targeted measles virus.

  Molecular therapy : the journal of the American Society of Gene Therapy 20071101

• From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis.

  Bioorganic & medicinal chemistry letters 20071101

• Hypoxanthine decreases equilibrative type of adenosine transport in lymphocytes from Lesch-Nyhan patients.

  European journal of clinical investigation 20071101

• Analysis of virulence and growth of a purine auxotrophic mutant of Xanthomonas oryzae pathovar oryzae.

  FEMS microbiology letters 20071101

• Overexpression of HAM1 gene detoxifies 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae.

  Current genetics 20071101

• Release of ATP in the central nervous system during systemic inflammation: real-time measurement in the hypothalamus of conscious rabbits.

  The Journal of physiology 20071101

• Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia.

  British journal of haematology 20071101

• Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency.

  Pediatric transplantation 20071101

• Genetic basis for retention of a critical virulence plasmid of Borrelia burgdorferi.

  Molecular microbiology 20071101

• Partial characterization of the proteome of the mouse striatum.

  Proteomics 20071101

• Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax.

  Biochimica et biophysica acta 20071101

• Purine catabolic enzymes and nitric oxide in patients with recurrent aphthous ulceration.

  Oral diseases 20071101

• Purinergic P2Y2 receptors induce increased MCP-1/CCL2 synthesis and release from rat alveolar and peritoneal macrophages.

  Journal of immunology (Baltimore, Md. : 1950) 20071101

• Nitrogen K-edge XANES - an overview of reference compounds used to identify unknown organic nitrogen in environmental samples.

  Journal of synchrotron radiation 20071101

• Evolving role of monoclonal antibodies in the treatment of chronic lymphocytic leukemia.

  Expert opinion on investigational drugs 20071101

• The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.

  PLoS genetics 20071101

• tRNASer acceptor stem: conformation and hydration of a microhelix in a crystal structure at 1.8 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20071101

• Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status.

  Environmental health perspectives 20071101

• [Successful use of cladribine in the treatment of an elderly woman with typical hairy cell leukemia].

  Gan to kagaku ryoho. Cancer & chemotherapy 20071101

• Processing of nuclear viroids in vivo: an interplay between RNA conformations.

  PLoS pathogens 20071101

• Nucleobase analogs for degenerate hybridization devised through conformational pairing analysis.

  BioTechniques 20071101

• [Chromatographic behavior of purine derivatives on cucurbit [6] uril monorotaxane-bonded silica stationary phase by high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20071101

• Antero-ventral internal pallidum stimulation improves behavioral disorders in Lesch-Nyhan disease.

  Movement disorders : official journal of the Movement Disorder Society 20071031

• Rpn10p is a receptor for ubiquitinated Gcn4p in proteasomal proteolysis.

  Molecules and cells 20071031

• Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.

  Biochemistry 20071030

• Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue.

  FEBS letters 20071030

• On the origin of biochemistry at an alkaline hydrothermal vent.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20071029

• Identification and biochemical characterization of unique secretory nucleases of the human enteric pathogen, Entamoeba histolytica.

  The Journal of biological chemistry 20071026

• A novel strategy to assemble the beta-diketo acid pharmacophore of HIV integrase inhibitors on purine nucleobase scaffolds.

  The Journal of organic chemistry 20071026

• Purine-mediated signalling triggers eye development.

  Nature 20071025

• Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.

  British journal of cancer 20071022

• Episomally driven antisense mRNA abrogates the hyperinducible expression and function of a unique cell surface class I nuclease in the primitive trypanosomatid parasite, Crithidia luciliae.

  Journal of molecular biology 20071019

• Ribavirin: analytical determinations since the origin until today.

  Journal of pharmaceutical and biomedical analysis 20071018

• Non-hematopoietic stem cell transplantation treatment of juvenile myelomonocytic leukemia: a retrospective analysis and definition of response criteria.

  Pediatric blood & cancer 20071015

• Four-stranded coordination helices containing silver-adenine (purine) metallaquartets.

  Inorganic chemistry 20071015

• Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.

  Neuroscience 20071012

• Synthesis of nucleotide analogues by a promiscuous phosphoribosyltransferase.

  Organic letters 20071011

• Spectroscopic and theoretical insights into sequence effects of aminofluorene-induced conformational heterogeneity and nucleotide excision repair.

  Biochemistry 20071009

• Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress.

  Annals of the New York Academy of Sciences 20071001

• The identification of (3R,4S)-5-fluoro-5-deoxy-D-ribulose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya.

  Bioorganic chemistry 20071001

• Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment?

  Inflammatory bowel diseases 20071001

• Specific type of interactions in the quaternary system of Cu(II), adenosine 5'-triphosphate, 1,11-diamino-4,8-diazaundecane and uridine.

  Journal of inorganic biochemistry 20071001

• Conditional overexpression of Stat3alpha in differentiating myeloid cells results in neutrophil expansion and induces a distinct, antiapoptotic and pro-oncogenic gene expression pattern.

  Journal of leukocyte biology 20071001

• Mammalian mismatches in nucleotide metabolism: implications for xenotransplantation.

  Molecular and cellular biochemistry 20071001

• A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation.

  Analytical biochemistry 20071001

• The tolerance to exchanges of the Watson Crick base pair in the hammerhead ribozyme core is determined by surrounding elements.

  RNA (New York, N.Y.) 20071001

• Determination of serum uric acid using high-performance liquid chromatography (HPLC)/isotope dilution mass spectrometry (ID-MS) as a candidate reference method.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071001

• Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63.

  Calcified tissue international 20071001

• Characterization of the adenine nucleoside specific phosphorylase of Bacillus cereus.

  Biochimica et biophysica acta 20071001

• Clofarabine: past, present, and future.

  Leukemia & lymphoma 20071001

• Binding isotope effects: boon and bane.

  Current opinion in chemical biology 20071001

• The RNAi-mediated silencing of xanthine dehydrogenase impairs growth and fertility and accelerates leaf senescence in transgenic Arabidopsis plants.

  Plant & cell physiology 20071001

• Corticosteroid-dependent eosinophilic oesophagitis: azathioprine and 6-mercaptopurine can induce and maintain long-term remission.

  European journal of gastroenterology & hepatology 20071001

• Characterization of N-deoxyribosyltransferase from Lactococcus lactis subsp. lactis.

  Biochimica et biophysica acta 20071001

• Structure of the nondiscriminating aspartyl-tRNA synthetase from the crenarchaeon Sulfolobus tokodaii strain 7 reveals the recognition mechanism for two different tRNA anticodons.

  Acta crystallographica. Section D, Biological crystallography 20071001

• Antiviral effects of PNA in duck hepatitis B virus infection model.

  Acta pharmacologica Sinica 20071001

• The use of beta-D-2,6-diaminopurine dioxolane with or without mycophenolate mofetil in drug-resistant HIV infection.

  AIDS (London, England) 20071001

• Primary chronic cold agglutinin disease: an update on pathogenesis, clinical features and therapy.

  Hematology (Amsterdam, Netherlands) 20071001

• Enhanced mutagenesis of Salmonella tester strains due to deletion of genes other than uvrB.

  Environmental and molecular mutagenesis 20071001

• Nicotinamide riboside kinase structures reveal new pathways to NAD+.

  PLoS biology 20071001

• The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy.

  Leukemia & lymphoma 20071001

• Universally sloppy parameter sensitivities in systems biology models.

  PLoS computational biology 20071001

• Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli.

  PLoS computational biology 20071001

• Identification of gene markers for formaldehyde exposure in humans.

  Environmental health perspectives 20071001

• Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa.

  PLoS pathogens 20071001

• Isolation and functional analysis of sulfite oxidase gene AtSO promoter from Arabidopsis thaliana.

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20071001

• Autologous stem cell transplantation for chronic lymphocytic leukemia.

  Seminars in hematology 20071001

• Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus.

  Chemistry & biology 20071001

• The epigenetics of mantle cell lymphoma.

  Current treatment options in oncology 20071001

• Oblimersen for the treatment of patients with chronic lymphocytic leukemia.

  Therapeutics and clinical risk management 20071001

• Glutamine phosphoribosylpyrophosphate amidotransferase-independent phosphoribosyl amine synthesis from ribose 5-phosphate and glutamine or asparagine.

  The Journal of biological chemistry 20070928

• 13C-enrichment at carbons 8 and 2 of uric acid after 13C-labeled folate dose in man.

  Biochemical and biophysical research communications 20070921

• Determination of purine and pyrimidine bases in natural and cultured Cordyceps using optimum acid hydrolysis followed by high performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20070921

• Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides.

  Journal of medicinal chemistry 20070920

• Treatment-related myelodysplastic syndrome and acute myelogenous leukemia in patients treated with ibritumomab tiuxetan radioimmunotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070920

• High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme.

  The Journal of biological chemistry 20070914

• Synthesis of oxepane ring containing monocyclic, conformationally restricted bicyclic and spirocyclic nucleosides from D-glucose: a cycloaddition approach.

  The Journal of organic chemistry 20070914

• Role of A(2A) adenosine receptors in regulation of opsonized E. coli-induced macrophage function.

  Purinergic signalling 20070905

• [Recurrent urinary lithiasis revealing hereditary xanthinuria].

  Presse medicale (Paris, France : 1983) 20070901

• The extracellular cardiac purine metabolome in sepsis.

  Shock (Augusta, Ga.) 20070901

• Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.

  Antiviral research 20070901

• Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs.

  Gene therapy 20070901

• Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice.

  American journal of physiology. Lung cellular and molecular physiology 20070901

• Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast.

  FEMS yeast research 20070901

• Cyclin-dependent kinase inhibitors block erythrocyte invasion and intraerythrocytic development of Babesia bovis in vitro.

  Parasitology 20070901

• Complete (1)H and (13)C NMR spectral assignment of alpha- and beta-adenosine, 2'-deoxyadenosine and their acetate derivatives.

  Magnetic resonance in chemistry : MRC 20070901

• Waldenström macroglobulinaemia.

  British journal of haematology 20070901

• Identification of a mitotic recombination hotspot on chromosome III of the asexual fungus Aspergillus niger and its possible correlation with [corrected] elevated basal transcription.

  Current genetics 20070901

• Efficacy and safety of allopurinol in patients with hypoxanthine-guanine phosphoribosyltransferase deficiency.

  Metabolism: clinical and experimental 20070901

• Arts syndrome is caused by loss-of-function mutations in PRPS1.

  American journal of human genetics 20070901

• Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic neuropathy (cmtx5).

  American journal of human genetics 20070901

• The role of DNA repair in chronic lymphocytic leukemia pathogenesis and chemotherapy resistance.

  Current oncology reports 20070901

• Chemoimmunotherapy of chronic lymphocytic leukemia.

  Best practice & research. Clinical haematology 20070901

• The role of stem-cell transplantation in chronic lymphocytic leukemia risk-adapted therapy.

  Best practice & research. Clinical haematology 20070901

• Fatal Epstein-Barr virus-associated lymphoproliferative disorder following treatment with a novel mTOR inhibitor for relapsed chronic lymphocytic leukemia leukemia cells.

  Haematologica 20070901

• A structure-based flexible search method for motifs in RNA.

  Journal of computational biology : a journal of computational molecular cell biology 20070901

• Orthologous transcription factors in bacteria have different functions and regulate different genes.

  PLoS computational biology 20070901

• Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection.

  PLoS genetics 20070901

• Structure-templated predictions of novel protein interactions from sequence information.

  PLoS computational biology 20070901

• Forodesine (BCX-1777, Immucillin H)--a new purine nucleoside analogue: mechanism of action and potential clinical application.

  Mini reviews in medicinal chemistry 20070901

• Adenosine deaminase activity in cats infected with feline immunodeficiency virus.

  The Journal of veterinary medical science 20070901

• Cannabinoid receptors expression in bone marrow trephine biopsy of chronic lymphocytic leukaemia patients treated with purine analogues.

  Experimental oncology 20070901

• Nelarabine: a novel purine antimetabolite antineoplastic agent.

  Clinical therapeutics 20070901

• [Differential gene expression profile in seasonal allergic rhinitis with and without asthma].

  Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20070901

• Second Joint Italian-German Purine Club Meeting: 'Progress in purinergic receptor pharmacology and function'.

  Purinergic signalling 20070901

• Structural and functional evolution of the P2Y(12)-like receptor group.

  Purinergic signalling 20070901

• P2 receptor-mediated modulation of neurotransmitter release-an update.

  Purinergic signalling 20070901

• Adenosine A(1) receptor: Functional receptor-receptor interactions in the brain.

  Purinergic signalling 20070901

• The role of ATP and adenosine in the brain under normoxic and ischemic conditions.

  Purinergic signalling 20070901

• Modification of neuropathic pain sensation through microglial ATP receptors.

  Purinergic signalling 20070901

• New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders.

  Purinergic signalling 20070901

• [(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions.

  Purinergic signalling 20070901

• MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine.

  Purinergic signalling 20070901

• Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury.

  Purinergic signalling 20070901

• Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels.

  Journal of medicinal chemistry 20070823

• Selective liquid CO2 extraction of purine alkaloids in different Ilex paraguariensis progenies grown under environmental influences.

  Journal of agricultural and food chemistry 20070822

• Mapping ligand interactions with the hyperpolarization activated cyclic nucleotide modulated (HCN) ion channel binding domain using a soluble construct.

  Biochemistry 20070821

• Acidity and proton affinity of hypoxanthine in the gas phase versus in solution: intrinsic reactivity and biological implications.

  The Journal of organic chemistry 20070817

• Virologic characterization of HIV type 1 with a codon 70 deletion in reverse transcriptase.

  Journal of acquired immune deficiency syndromes (1999) 20070815

• Anti-malarial activity of N6-modified purine analogues.

  Bioorganic & medicinal chemistry 20070815

• Effects of organosulfurs, isothiocyanates and vitamin C towards hydrogen peroxide-induced oxidative DNA damage (strand breaks and oxidized purines/pyrimidines) in human hepatoma cells.

  Chemico-biological interactions 20070815

• Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.

  European journal of pharmacology 20070813

• Structural and functional basis for (S)-allantoin formation in the ureide pathway.

  The Journal of biological chemistry 20070810

• CH/pi interactions in DNA and proteins. A theoretical study.

  The journal of physical chemistry. B 20070809

• hTERT-targeted E. coli purine nucleoside phosphorylase gene/6-methylpurine deoxyribose therapy for pancreatic cancer.

  Chinese medical journal 20070805

• P-BOSS: a new filtering method for treasure hunting in metabolomics.

  Journal of chromatography. A 20070803

• Fluorinated alcohol mediated control over cis vs trans opening of benzo[a]pyrene-7,8-diol 9,10-epoxides at C-10 by the exocyclic amino groups of O6-allyl protected deoxyguanosine and of deoxyadenosine.

  The Journal of organic chemistry 20070803

• Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.

  The Journal of investigative dermatology 20070801

• Role of CNT3 in the transepithelial flux of nucleosides and nucleoside-derived drugs.

  The Journal of physiology 20070801

• The anti-schistosomal drug praziquantel is an adenosine antagonist.

  Parasitology 20070801

• Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: a cautionary tale?

  Inflammatory bowel diseases 20070801

• Tissue-specific aberrations of gene expression in HPRT-deficient mice: functional complexity in a monogenic disease?

  Molecular therapy : the journal of the American Society of Gene Therapy 20070801

• Replication-associated purine asymmetry may contribute to strand-biased gene distribution.

  Genomics 20070801

• Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP.

  Bioorganic & medicinal chemistry letters 20070801

• Molecules targeting the purine salvage pathway in Apicomplexan parasites.

  Trends in parasitology 20070801

• Phosphoproteomic analysis of neuronal cell death by glutamate-induced oxidative stress.

  Proteomics 20070801

• Effects of feeding fat-coated butyrate on mucosal morphology and function in the small intestine of the pig.

  Journal of animal physiology and animal nutrition 20070801

• The role of mitochondria in protection of the heart by preconditioning.

  Biochimica et biophysica acta 20070801

• Development of a liquid chromatography-electrospray ionization tandem mass spectrometry method for detecting oxaliplatin-DNA intrastrand cross-links in biological samples.

  Chemical research in toxicology 20070801

• Morphine enhances purine nucleotide catabolism in vivo and in vitro.

  Acta pharmacologica Sinica 20070801

• Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease.

  Journal of clinical gastroenterology 20070801

• Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus.

  The European journal of neuroscience 20070801

• Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase.

  PLoS biology 20070801

• Novel protease and polymerase inhibitors for the treatment of hepatitis C virus infection.

  Expert opinion on investigational drugs 20070801

• Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria.

  PLoS genetics 20070801

• Origin of informational polymers and the search for non-terran life: protection of the polymeric state of DNA by phosphate minerals.

  Astrobiology 20070801

• Changes in serum adenosine deaminase activity during normal pregnancy.

  Journal of Korean medical science 20070801

• The role of hematopoietic stem cell transplantation in Chronic Lymphocytic Leukemia.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070801

• Oxidatively damaged DNA and inflammation in the liver of dyslipidemic ApoE-/- mice exposed to diesel exhaust particles.

  Toxicology 20070731

• Phosphonated carbocyclic 2'-oxa-3'-azanucleosides as new antiretroviral agents.

  Journal of medicinal chemistry 20070726

• Mechanism of deactivation of triplet-excited riboflavin by ascorbate, carotenoids, and tocopherols in homogeneous and heterogeneous aqueous food model systems.

  Journal of agricultural and food chemistry 20070725

• Nonpolar isosteres of damaged DNA bases: effective mimicry of mutagenic properties of 8-oxopurines.

  Journal of the American Chemical Society 20070718

• Fludarabine-mediated suppression of the excision repair enzyme ERCC1 contributes to the cytotoxic synergy with the DNA minor groove crosslinking agent SJG-136 (NSC 694501) in chronic lymphocytic leukaemia cells.

  British journal of cancer 20070716

• Use of pathway analysis and genome context methods for functional genomics of Mycoplasma pneumoniae nucleotide metabolism.

  Gene 20070715

• N9-benzyl-substituted 1,3-dimethyl- and 1,3-dipropyl-pyrimido[2,1-f]purinediones: synthesis and structure-activity relationships at adenosine A1 and A2A receptors.

  Bioorganic & medicinal chemistry 20070715

• Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution.

  Cancer research 20070715

• Photoreaction at 5'-(G/C)AA(Br)UT-3' sequence in duplex DNA: efficient generation of uracil-5-yl radical by charge transfer.

  Journal of the American Chemical Society 20070704

• Amino acid residues of Leishmania donovani cyclophilin key to interaction with its adenosine kinase: biological implications.

  Biochemistry 20070703

• Adenosine ecto-deaminase (ecto-ADA) from porcine cerebral cortex synaptic membrane.

  Brain research 20070702

• Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

  Medicinal research reviews 20070701

• Molecular modeling of purinergic receptor P2Y12 and interaction with its antagonists.

  Journal of molecular graphics & modelling 20070701

• Differential physiological and developmental expression of the UapA and AzgA purine transporters in Aspergillus nidulans.

  Fungal genetics and biology : FG & B 20070701

• Pathway analysis identifies perturbation of genetic networks induced by butyrate in a bovine kidney epithelial cell line.

  Functional & integrative genomics 20070701

• Heavy water labeling method for measuring the effect of genistein on mammary gland carcinogenesis.

  Molecular and cellular biochemistry 20070701

• Transcriptome profile of dendritic cells during malaria: cAMP regulation of IL-6.

  Cellular microbiology 20070701

• Gene expression and characterization of 2-keto-3-deoxygluconate kinase, a key enzyme in the modified Entner-Doudoroff pathway of the aerobic and acidophilic hyperthermophile Sulfolobus tokodaii.

  Protein expression and purification 20070701

• Complete mitochondrial genome of the bullhead torrent catfish, Liobagrus obesus (Siluriformes, Amblycipididae): Genome description and phylogenetic considerations inferred from the Cyt b and 16S rRNA genes.

  Gene 20070701

• Control of basal extracellular adenosine concentration in rat cerebellum.

  The Journal of physiology 20070701

• Spreading dilatation to luminal perfusion of ATP and UTP in rat isolated small mesenteric arteries.

  The Journal of physiology 20070701

• Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR).

  Gene 20070701

• Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei.

  Molecular and biochemical parasitology 20070701

• 1H and 13C NMR study of the complex formed by copper(II) with the nucleoside antibiotic sinefungin.

  Journal of inorganic biochemistry 20070701

• Chemical genetic identification of glutamine phosphoribosylpyrophosphate amidotransferase as the target for a novel bleaching herbicide in Arabidopsis.

  Plant physiology 20070701

• Novel algorithms reveal streptococcal transcriptomes and clues about undefined genes.

  PLoS computational biology 20070701

• Update on front-line therapy for follicular lymphoma: chemo-immunotherapy with rituximab and survival.

  Expert review of anticancer therapy 20070701

• Divergent evolution of human p53 binding sites: cell cycle versus apoptosis.

  PLoS genetics 20070701

• Pemetrexed and oxaliplatin for metastatic colorectal cancer: results of a phase I Mayo Cancer Center Research Consortium trial, MC0248.

  Clinical colorectal cancer 20070701

• A brief primer on treatments of cutaneous T cell lymphoma, newly approved or late in development.

  Journal of drugs in dermatology : JDD 20070701

• From purines to basic biochemical concepts: Experiments for high school students.

  Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20070701

• A quinoxaline 1,4-di-N-oxide derivative induces DNA oxidative damage not attenuated by vitamin C and E treatment.

  Chemico-biological interactions 20070630

• New platinum(II) complexes containing both an O,O'-chelated acetylacetonate ligand and a sulfur ligand in the platinum coordination sphere induce apoptosis in HeLa cervical carcinoma cells.

  Biochemical pharmacology 20070630

• Electron transfer between guanosine radical and amino acids in aqueous solution. 1. Reduction of guanosine radical by tyrosine.

  The journal of physical chemistry. B 20070628

• Simultaneous analysis of catechins, gallic acid, strictinin, and purine alkaloids in green tea by using catechol as an internal standard.

  Journal of agricultural and food chemistry 20070627

• Transition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases.

  Journal of the American Chemical Society 20070627

• Mitsunobu coupling of nucleobases and alcohols: an efficient, practical synthesis for novel nonsugar carbon nucleosides.

  The Journal of organic chemistry 20070622

• Efficient syntheses of C(8)-aryl adducts of adenine and guanine formed by reaction of radical cation metabolites of carcinogenic polycyclic aromatic hydrocarbons with DNA.

  The Journal of organic chemistry 20070622

• Complex retention behavior of pyrimidines on biomembrane-mimic immobilized-artificial-membrane phase.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

• The identification of similarities between biological networks: application to the metabolome and interactome.

  Journal of molecular biology 20070615

• Complementation of the oxidatively damaged DNA repair defect in Cockayne syndrome A and B cells by Escherichia coli formamidopyrimidine DNA glycosylase.

  Free radical biology & medicine 20070615

• Computational clues for a new mechanism in the glycosylase activity of the human DNA repair protein hOGG1. A generalized paradigm for purine-repairing systems?

  The journal of physical chemistry. B 20070614

• Complex changes in ecto-nucleoside 5'-triphosphate diphosphohydrolase expression in hypoxanthine phosphoribosyl transferase deficiency.

  Neuroscience letters 20070608

• Understanding the isomerization of the HIV-1 dimerization initiation domain by the nucleocapsid protein.

  Journal of molecular biology 20070608

• Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice.

  Oncogene 20070607

• Acyclic ribooxacarbenium ion mimics as transition state analogues of human and malarial purine nucleoside phosphorylases.

  Journal of the American Chemical Society 20070606

• Hairy cell leukaemia complicated by anti-MAG paraproteinemic demyelinating neuropathy: resolution of neurological syndrome after cladribrine treatment.

  Leukemia research 20070601

• Simultaneous determination of a selective adenosine 2A agonist, BMS-068645, and its acid metabolite in human plasma by liquid chromatography-tandem mass spectrometry--evaluation of the esterase inhibitor, diisopropyl fluorophosphate, in the stabilization of a labile ester-containing drug.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

• Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release.

  The Journal of physiology 20070601

• Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity.

  Proteins 20070601

• Purine and pyrimidine receptors.

  Cellular and molecular life sciences : CMLS 20070601

• Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070601

• A new method for the construction of a mutant library with a predictable occurrence rate using Poisson distribution.

  Journal of microbiological methods 20070601

• Fabrication and characterization of open-tubular CEC modified with tentacle-type metal-chelating polymer chains.

  Electrophoresis 20070601

• Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus.

  Journal of neurochemistry 20070601

• Quantitative proteomic comparison of mouse peroxisomes from liver and kidney.

  Proteomics 20070601

• Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor.

  European journal of immunology 20070601

• Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine.

  International journal of oncology 20070601

• Nucleobase-dependent reactivity of a quinone metabolite of pentachlorophenol.

  Chemical research in toxicology 20070601

• Therapeutic issues in HIV/HCV-coinfected patients.

  Journal of viral hepatitis 20070601

• Characterization of adducts formed in the reaction of glutaraldehyde with 2'-deoxyadenosine.

  Chemical research in toxicology 20070601

• Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro.

  Journal of veterinary science 20070601

• Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions.

  Journal of inherited metabolic disease 20070601

• A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis.

  Arthritis and rheumatism 20070601

• Legumes symbioses: absence of Nod genes in photosynthetic bradyrhizobia.

  Science (New York, N.Y.) 20070601

• The effect of local nucleotides on synonymous codon usage in the honeybee (Apis mellifera L.) genome.

  Journal of molecular evolution 20070601

• Molecular genetic analysis of purine nucleobase transport in Leishmania major.

  Molecular microbiology 20070601

• The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi.

  Molecular microbiology 20070601

• Purine and cytokine concentrations in the renal vein of the allograft during reperfusion.

  Transplantation proceedings 20070601

• Alemtuzumab in chronic lymphocytic leukemia.

  Current oncology (Toronto, Ont.) 20070601

• Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans.

  PLoS pathogens 20070601

• Adenine synthesis in interstellar space: mechanisms of prebiotic pyrimidine-ring formation of monocyclic HCN-pentamers.

  Astrobiology 20070601

• Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.

  Journal of child neurology 20070601

• Equine metabolic myopathies with emphasis on the diagnostic approach. Comparison with human myopathies. A review.

  The Veterinary quarterly 20070601

• Aminohydrolases acting on adenine, adenosine and their derivatives.

  Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601

• Sustained release of acyclovir from nano-liposomes and nano-niosomes: an in vitro study.

  International journal of nanomedicine 20070601

• Strong and weak hydrogen bonds in drug-DNA complexes: a statistical analysis.

  Journal of biosciences 20070601

• Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices.

  Purinergic signalling 20070601

• Ecto-5'-nucleotidase and intestinal ion secretion by enteropathogenic Escherichia coli.

  Purinergic signalling 20070601

• Mechanisms of over-activated innate immune system regulation in autoimmune and neurodegenerative disorders.

  Neuropsychiatric disease and treatment 20070601

• Synthesis of 5'-methylthio coformycins: specific inhibitors for malarial adenosine deaminase.

  Journal of the American Chemical Society 20070530

• Determination of redox potentials for the Watson-Crick base pairs, DNA nucleosides, and relevant nucleoside analogues.

  The journal of physical chemistry. B 20070517

• Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents.

  Biochemical pharmacology 20070515

• TOR-induced resistance to toxic adenosine analogs in Leishmania brought about by the internalization and degradation of the adenosine permease.

  Experimental cell research 20070515

• S(N)Ar displacements with 6-(fluoro, chloro, bromo, iodo, and alkylsulfonyl)purine nucleosides: synthesis, kinetics, and mechanism1.

  Journal of the American Chemical Society 20070509

• Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans.

  Biochemistry 20070508

• Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors.

  Journal of medicinal chemistry 20070503

• Allantoin has a limited role as nitrogen source in cultured coffee cells.

  Journal of plant physiology 20070501

• Role of roscovitine and IBMX on kinetics of nuclear and cytoplasmic maturation of bovine oocytes in vitro.

  Animal reproduction science 20070501

• Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection.

  Cellular microbiology 20070501

• Evidence of a species complex within the food-borne trematode Opisthorchis viverrini and possible co-evolution with their first intermediate hosts.

  International journal for parasitology 20070501

• A model for triplet mutation formation based on error-prone translesional DNA synthesis opposite UV photolesions.

  DNA repair 20070501

• Management options for adenosine deaminase deficiency; proceedings of the EBMT satellite workshop (Hamburg, March 2006).

  Clinical immunology (Orlando, Fla.) 20070501

• Interguanine hydrogen-bonding patterns in adducts with water and Zn-purine complexes (purine is 9-methyladenine and 9-methylguanine). Unexpected preference of Zn(II) for adenine-N7 over guanine-N7.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501

• Fludarabine induces apoptosis of human T-cell leukemia virus type 1-infected T cells via inhibition of the nuclear factor-kappaB signal pathway.

  Leukemia 20070501

• Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon.

  British journal of pharmacology 20070501

• Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.

  Molecular genetics and metabolism 20070501

• Pyrimidine transport activities in trypanosomes.

  Trends in parasitology 20070501

• Basal ganglia dopamine loss due to defect in purine recycling.

  Neurobiology of disease 20070501

• Neighboring group participation in the transition state of human purine nucleoside phosphorylase.

  Biochemistry 20070501

• Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.

  The FEBS journal 20070501

• Successful cardiac transplantation in Barth syndrome--single-centre experience of four patients.

  Pediatric transplantation 20070501

• 13C enrichment of carbons 2 and 8 of purine by folate-dependent reactions after [13C]formate and [2-13C]glycine dosing in adult humans.

  Metabolism: clinical and experimental 20070501

• Nitric oxide generation is associated with an unbalance of protein tyrosine phosphatases during liver transplantation.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070501

• Mouse equilibrative nucleoside transporter 2 (mENT2) transports nucleosides and purine nucleobases differing from human and rat ENT2.

  Biological & pharmaceutical bulletin 20070501

• 2-Chloro-6-(2-furyl)-9-(4-methoxybenzyl)-9H-purine.

  Acta crystallographica. Section C, Crystal structure communications 20070501

• Z-DNA, an active element in the genome.

  Frontiers in bioscience : a journal and virtual library 20070501

• Skin lesions in chronic lymphocytic leukemia.

  Leukemia & lymphoma 20070501

• Fluorescence-based adenylyl cyclase assay adaptable to high throughput screening.

  Combinatorial chemistry & high throughput screening 20070501

• RNA interference tolerates 2'-fluoro modifications at the Argonaute2 cleavage site.

  Chemistry & biodiversity 20070501

• Tenofovir disoproxil fumarate for prevention of HIV infection in women: a phase 2, double-blind, randomized, placebo-controlled trial.

  PLoS clinical trials 20070501

• Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.

  The Journal of biological chemistry 20070427

• The role of arginine 310 in catalysis and substrate specificity in xanthine dehydrogenase from Rhodobacter capsulatus.

  The Journal of biological chemistry 20070427

• Structural analysis of a ternary complex of allantoate amidohydrolase from Escherichia coli reveals its mechanics.

  Journal of molecular biology 20070427

• Phase I trial and pharmacokinetic study of pemetrexed in children with refractory solid tumors: the Children's Oncology Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070420

• PRODAN-conjugated DNA: synthesis and photochemical properties.

  Journal of the American Chemical Society 20070418

• Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV.

  Bioorganic & medicinal chemistry letters 20070415

• The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum.

  Neuroscience 20070414

• Characterization of DNA--protein cross-links induced by oxanine: cellular damage derived from nitric oxide and nitrous acid.

  Biochemistry 20070403

• Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070401

• Correlation of ZAP-70 expression in B cell leukemias to the ex vivo response to a combination of fludarabine/genistein.

  Cancer immunology, immunotherapy : CII 20070401

• Prebiotic microreactors: a synthesis of purines and dihydroxy compounds in aqueous aerosol.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20070401

• Biochemical and pharmacological characterization of P-site inhibitors on homodimeric guanylyl cyclase domain from natriuretic peptide receptor-A.

  Biochemical pharmacology 20070401

• The HIV-1 central DNA flap region contains a 'flapping' third strand.

  Biophysical chemistry 20070401

• Structure of the d(CGCGAATTCGCG)2 complex of the minor groove binding alkylating agent alkamin studied by mass spectrometry.

  Molecular pharmacology 20070401

• Oxidative damage in nucleic acids and Parkinson's disease.

  Journal of neuroscience research 20070401

• Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate.

  Journal of biochemistry 20070401

• Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts.

  Leukemia 20070401

• Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial.

  Archives of medical research 20070401

• Synthesis of some novel substituted purine derivatives as potential anticancer, anti-HIV-1 and antimicrobial agents.

  Archiv der Pharmazie 20070401

• Effects of sucrose on plasma concentrations and urinary excretion of purine bases.

  Metabolism: clinical and experimental 20070401

• Radiosensitization by nitric oxide at low radiation doses.

  Radiation research 20070401

• Current treatment options in prolymphocytic leukemia.

  Medical science monitor : international medical journal of experimental and clinical research 20070401

• M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog.

  PLoS pathogens 20070401

• Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation.

  PLoS pathogens 20070401

• Preparation of guanine and diaminopurine from biuret. Part III.

  Chemistry & biodiversity 20070401

• Allogeneic stem cell transplantation for patients with advanced hematological malignancies: comparison of fludarabine-based reduced intensity conditioning versus myeloablative conditioning.

  Journal of Korean medical science 20070401

• Hormesis and its place in nonmonotonic dose-response relationships: some scientific reality checks.

  Environmental health perspectives 20070401

• A novel variant L263F in human inosine 5'-monophosphate dehydrogenase 2 is associated with diminished enzyme activity.

  Pharmacogenetics and genomics 20070401

• Community-based phase II trial of pentostatin, cyclophosphamide, and rituximab (PCR) biochemotherapy in chronic lymphocytic leukemia and small lymphocytic lymphoma.

  Cancer biotherapy & radiopharmaceuticals 20070401

• Treatment of Waldenstrom's Macroglobulinemia.

  Current treatment options in oncology 20070401

• Outline for writing an article for current treatment options in oncology: splenic lymphoma with villous lymphocytes.

  Current treatment options in oncology 20070401

• Splenic marginal zone lymphoma with and without villous lymphocytes.

  Current treatment options in oncology 20070401

• Hairy Cell Leukemia.

  Current treatment options in oncology 20070401

• Molecular and functional analyses of a novel class I secretory nuclease from the human pathogen, Leishmania donovani.

  The Journal of biological chemistry 20070330

• In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase.

  Biochemistry 20070327

• How do size-expanded DNA nucleobases enhance duplex stability? Computational analysis of the hydrogen-bonding and stacking ability of xDNA bases.

  The journal of physical chemistry. B 20070322

• Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery.

  Journal of the American Chemical Society 20070321

• 8-Azaguanine reporter of purine ionization states in structured RNAs.

  Journal of the American Chemical Society 20070321

• [Advances in the management of gout].

  Revue medicale suisse 20070321

• The c-Myc target gene Rcl (C6orf108) encodes a novel enzyme, deoxynucleoside 5'-monophosphate N-glycosidase.

  The Journal of biological chemistry 20070316

• Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2.

  Biochemical and biophysical research communications 20070316

• High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO.

  Physiological genomics 20070314

• Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.

  Journal of molecular biology 20070309

• Lymphoblasts of women with BRCA1 mutations are deficient in cellular repair of 8,5'-Cyclopurine-2'-deoxynucleosides and 8-hydroxy-2'-deoxyguanosine.

  Biochemistry 20070306

• Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases.

  The Journal of biological chemistry 20070302

• Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.

  Brain & development 20070301

• Purification of human malaria parasite hypoxanthine guanine xanthine phosphoribosyltransferase (HGXPRT) using immobilized Reactive Red 120.

  Protein expression and purification 20070301

• Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.

  Molecular and biochemical parasitology 20070301

• Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.

  Molecular pharmacology 20070301

• Synthesis, characterization and assessment of the cytotoxic properties of cis and trans-[Pd(L)(2)Cl(2)] complexes involving 6-benzylamino-9-isopropylpurine derivatives.

  Journal of inorganic biochemistry 20070301

• The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients.

  Human psychopharmacology 20070301

• A Francisella tularensis subspecies novicida purF mutant, but not a purA mutant, induces protective immunity to tularemia in mice.

  Vaccine 20070301

• Role of neuronal nitric oxide in the dopamine deficit of HPRT-deficient mice.

  Metabolic brain disease 20070301

• NF-kappaB activation in development and progression of cancer.

  Cancer science 20070301

• Effects of low rumen-degradable protein or abomasal fructan infusion on diet digestibility and urinary nitrogen excretion in lactating dairy cows.

  Journal of dairy science 20070301

• FMRP mediates mGluR5-dependent translation of amyloid precursor protein.

  PLoS biology 20070301

• Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2.

  The FEBS journal 20070301

• Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients.

  Circulation journal : official journal of the Japanese Circulation Society 20070301

• Structure of 5-formyltetrahydrofolate cyclo-ligase from Bacillus anthracis (BA4489).

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070301

• CD4+ cell count decline despite HIV suppression: a probable didanosine-valganciclovir interaction.

  The Annals of pharmacotherapy 20070301

• Adenosine enhances cytosolic phosphorylation potential and ventricular contractility in stunned guinea pig heart: receptor-mediated and metabolic protection.

  Journal of applied physiology (Bethesda, Md. : 1985) 20070301

• Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases.

  Current drug targets 20070301

• The tightly regulated promoter of the xanA gene of Aspergillus nidulans is included in a helitron.

  Molecular microbiology 20070301

• Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen.

  PLoS medicine 20070301

• 6-mercaptopurine (6-MP) entrapped stealth liposomes for improvement of leukemic treatment without hepatotoxicity and nephrotoxicity.

  Cancer investigation 20070301

• Fluocinolone acetonide intravitreal sustained release device--a new addition to the armamentarium of uveitic management.

  International journal of nanomedicine 20070301

• Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon.

  Journal of structural and functional genomics 20070301

• Therapy of autoimmune bullous diseases.

  Therapeutics and clinical risk management 20070301

• Outcomes and quality of life issues in the pharmacological management of benign prostatic hyperplasia (BPH).

  Therapeutics and clinical risk management 20070301

• Chemotactic activity of extracellular nucleotideson human immune cells.

  Purinergic signalling 20070301

• Nucleotide receptor signalling and the generation of reactive oxygen species.

  Purinergic signalling 20070301

• Extracellular NAD and ATP: Partners in immune cell modulation.

  Purinergic signalling 20070301

• The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides.

  Purinergic signalling 20070301

• Adenosine and lymphocyte regulation.

  Purinergic signalling 20070301

• Purinergic modulation of microglial cell activation.

  Purinergic signalling 20070301

• P2 receptors in atherosclerosis and postangioplasty restenosis.

  Purinergic signalling 20070301

• CD39 and control of cellular immune responses.

  Purinergic signalling 20070301

• Palladium-catalyzed cross-coupling reactions in c6 modifications of purine nucleosides.

  Current protocols in nucleic acid chemistry 20070301

• Effects of a dietary organic acid mixture and of dietary fibre levels on ileal and faecal nutrient apparent digestibility, bacterial nitrogen flow, microbial metabolite concentrations and rate of passage in the digestive tract of pigs.

  Animal : an international journal of animal bioscience 20070301

• [Cloning and fusion expression of adenosine deaminase of Schistosoma japonicum].

  Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20070227

• HPLC separation of some purine and pyrimidine derivatives on Chromolith Performance Si monolithic column.

  Journal of biochemical and biophysical methods 20070223

• 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.

  Journal of medicinal chemistry 20070222

• Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization.

  Journal of the American Chemical Society 20070221

• Biomarkers for phenol carcinogen exposure act as pH-sensing fluorescent probes.

  Journal of the American Chemical Society 20070221

• Simultaneous detection of purine and pyrimidine at highly boron-doped diamond electrodes by using liquid chromatography.

  Talanta 20070215

• Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.

  Biochemistry 20070213

• Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells.

  British journal of cancer 20070212

• tRNA's wobble decoding of the genome: 40 years of modification.

  Journal of molecular biology 20070209

• Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

  The Journal of biological chemistry 20070202

• Implication of site quality on mitochondrial electron transport activity and its interaction with temperature in feral Mya arenaria clams from the Saguenay Fjord.

  Environmental research 20070201

• Towards the mechanism of trimeric purine nucleoside phosphorylases: stopped-flow studies of binding of multisubstrate analogue inhibitor - 2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine.

  Biophysical chemistry 20070201

• Analysis of aminoimidazole ribosides by capillary electrophoresis--diagnosing defects in second part of purine biosynthetic pathway.

  Clinica chimica acta; international journal of clinical chemistry 20070201

• Shaping of monocyte and macrophage function by adenosine receptors.

  Pharmacology & therapeutics 20070201

• Roscovitine regulates invasive breast cancer cell (MDA-MB231) proliferation and survival through cell cycle regulatory protein cdk5.

  Experimental and molecular pathology 20070201

• Xanthinuria type I: a rare cause of urolithiasis.

  Pediatric nephrology (Berlin, Germany) 20070201

• Purine and pyrimidine nucleosides preserve human astrocytoma cell adenylate energy charge under ischemic conditions.

  Neurochemistry international 20070201

• Pharmacological inhibition of the MAPK/ERK pathway increases sensitivity to 2-chloro-2'-deoxyadenosine (CdA) in the B-cell leukemia cell line EHEB.

  Biochemical pharmacology 20070201

• Purinergic signaling regulates neural progenitor cell expansion and neurogenesis.

  Developmental biology 20070201

• Capillary electrophoretic method for nucleotide analysis in cells: application on inherited metabolic disorders.

  Electrophoresis 20070201

• Looking for organization patterns of highly expressed genes: purine-pyrimidine composition of precursor mRNAs.

  Journal of molecular evolution 20070201

• Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue.

  Archives of medical research 20070201

• Effects of essential oils on digestion, ruminal fermentation, rumen microbial populations, milk production, and milk composition in dairy cows fed alfalfa silage or corn silage.

  Journal of dairy science 20070201

• Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase.

  Acta crystallographica. Section D, Biological crystallography 20070201

• 'Multicolor' electrochemical labeling of DNA hybridization probes with osmium tetroxide complexes.

  Analytical chemistry 20070201

• Alemtuzumab in chronic lymphocytic leukemia.

  Future oncology (London, England) 20070201

• Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.

  Structure (London, England : 1993) 20070201

• The role of mitochondrial DNA mutations in mammalian aging.

  PLoS genetics 20070201

• Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different.

  Biochemistry. Biokhimiia 20070201

• Systemic monotherapy vs combination therapy for CTCL: rationale and future strategies.

  Oncology (Williston Park, N.Y.) 20070201

• Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.

  Biochemistry 20070123

• Hydrodynamic studies on the quaternary structure of recombinant mouse Purbeta.

  The Journal of biological chemistry 20070119

• Pre-steady-state kinetic study of substrate specificity of Escherichia coli formamidopyrimidine--DNA glycosylase.

  Biochemistry 20070116

• Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity.

  Biochemistry 20070116

• Direct labeling microRNA with an electrocatalytic moiety and its application in ultrasensitive microRNA assays.

  Biosensors & bioelectronics 20070115

• Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides.

  Bioorganic & medicinal chemistry 20070115

• A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days.

  British journal of cancer 20070115

• Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070115

• Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs.

  The Journal of biological chemistry 20070112

• 4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure.

  Biochemistry 20070109

• Different DNA repair strategies to combat the threat from 8-oxoguanine.

  Mutation research 20070103

• Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants.

  Gene therapy 20070101

• Gene duplication and inactivation in the HPRT gene family.

  Genomics 20070101

• Prokaryotes that grow optimally in acid have purine-poor codons in long open reading frames.

  Extremophiles : life under extreme conditions 20070101

• Conformations of adducts formed between the genotoxic benzo[a]pyrene-7,8-dione and nucleosides studied by density functional theory.

  Biophysical chemistry 20070101

• Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-kappaB.

  American journal of physiology. Renal physiology 20070101

• A purine analog kinase inhibitor, calcium/calmodulin-dependent protein kinase II inhibitor 59, reveals a role for calcium/calmodulin-dependent protein kinase II in insulin-stimulated glucose transport.

  Endocrinology 20070101

• Mechanisms of DNA damage and insight into mutations by chromium(VI) in the presence of glutathione.

  Journal of inorganic biochemistry 20070101

• Molecular analysis of HPRT deficiencies: an update of the spectrum of Asian mutations with novel mutations.

  Molecular genetics and metabolism 20070101

• Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: the EBMT transplant consensus.

  Leukemia 20070101

• Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure.

  Clinical biochemistry 20070101

• Synthesis and biological activity of 5',9-anhydro-3-purine-isonucleosides as potential anti-hepatitis C virus agents.

  Nucleosides, nucleotides & nucleic acids 20070101

• Temperature-dependent effects of cadmium and purine nucleotides on mitochondrial aconitase from a marine ectotherm, Crassostrea virginica: a role of temperature in oxidative stress and allosteric enzyme regulation.

  The Journal of experimental biology 20070101

• Involvement of rapid nucleotide synthesis in recovery from phosphate starvation of Catharanthus roseus cells.

  Journal of experimental botany 20070101

• Revised procedures for yeast metabolites extraction: application to a glucose pulse to carbon-limited yeast cultures, which reveals a transient activation of the purine salvage pathway.

  Yeast (Chichester, England) 20070101

• Monitoring diet effects via biofluids and their implications for metabolomics studies.

  Analytical chemistry 20070101

• Exogenous purines induce differential responses in the proximal and distal regions of the possum sphincter of Oddi.

  Autonomic & autacoid pharmacology 20070101

• An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti.

  BMC genomics 20070101

• Identification of putative cis-regulatory elements in Cryptosporidium parvum by de novo pattern finding.

  BMC genomics 20070101

• Energetics of the protein-DNA-water interaction.

  BMC structural biology 20070101

• Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins.

  Molecular pharmaceutics 20070101

• Protein and DNA sequence determinants of thermophilic adaptation.

  PLoS computational biology 20070101

• Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation.

  PLoS genetics 20070101

• Conformation-specific recognition of carcinogen-DNA adduct in escherichia coli nucleotide excision repair.

  Chemical research in toxicology 20070101

• The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms.

  BMC genomics 20070101

• GraphDNA: a Java program for graphical display of DNA composition analyses.

  BMC bioinformatics 20070101

• Role of adenosine receptors in the treatment of asthma and chronic obstructive pulmonary disease: recent developments.

  Drugs in R&D 20070101

• On the action of methotrexate and 6-mercaptopurine on M. avium subspecies paratuberculosis.

  PloS one 20070101

• Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.

  BMC cancer 20070101

• Independent evolution of the specialized pharyngeal jaw apparatus in cichlid and labrid fishes.

  BMC evolutionary biology 20070101

• Targeting purine and pyrimidine metabolism in human apicomplexan parasites.

  Current drug targets 20070101

• Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain.

  Genome biology 20070101

• Classification of microarray data using gene networks.

  BMC bioinformatics 20070101

• The +4G site in Kozak consensus is not related to the efficiency of translation initiation.

  PloS one 20070101

• Serum uric acid to creatinine ratio in patients with chronic obstructive pulmonary disease.

  Lung 20070101

• Characterization of relationships between transcriptional units and operon structures in Bacillus subtilis and Escherichia coli.

  BMC genomics 20070101

• [Iminosugars: current and future therapeutic applications].

  Annales pharmaceutiques francaises 20070101

• Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis.

  International journal of medical sciences 20070101

• Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4.

  Virology journal 20070101

• Patterns and rates of intron divergence between humans and chimpanzees.

  Genome biology 20070101

• Mass spectrometric study of dirhenium biscarboxylate:purine dinucleotide complexes.

  Rapid communications in mass spectrometry : RCM 20070101

• Results of a phase II study of 506U78 in cutaneous T-cell lymphoma and peripheral T-cell lymphoma: CALGB 59901.

  Leukemia & lymphoma 20070101

• Cyclin-dependent kinase inhibitor seliciclib shows in vitro activity in diffuse large B-cell lymphomas.

  Leukemia & lymphoma 20070101

• A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis.

  Theoretical biology & medical modelling 20070101

• Strategy of transcription regulation in the budding yeast.

  PloS one 20070101

• Chemotherapeutic strategies against Trypanosoma brucei: drug targets vs. drug targeting.

  Current pharmaceutical design 20070101

• Nucleoside transport as a potential target for chemotherapy in malaria.

  Current pharmaceutical design 20070101

• Adenosine metabolism in Toxoplasma gondii: potential targets for chemotherapy.

  Current pharmaceutical design 20070101

• Purine metabolism in Mycobacterium tuberculosis as a target for drug development.

  Current pharmaceutical design 20070101

• Traceless solid-phase synthesis and biological evaluation of purine analogs as inhibitors of multidrug resistance protein 4.

  Journal of combinatorial chemistry 20070101

• Quantifying the metabolic capabilities of engineered Zymomonas mobilis using linear programming analysis.

  Microbial cell factories 20070101

• Aromatic heterocycle-based DPP-IV inhibitors: xanthines and related structural types.

  Current topics in medicinal chemistry 20070101

• Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response.

  Virology journal 20070101

• Fast computation of distance estimators.

  BMC bioinformatics 20070101

• Transcriptional profiling of Actinobacillus pleuropneumoniae under iron-restricted conditions.

  BMC genomics 20070101

• Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada.

  Environmental health perspectives 20070101

• The role of the purinergic P2X7 receptor in inflammation.

  Journal of inflammation (London, England) 20070101

• Reactome: a knowledge base of biologic pathways and processes.

  Genome biology 20070101

• Quantum mechanical energy-based screening of combinatorially generated library of tautomers. TauTGen: a tautomer generator program.

  Journal of chemical information and modeling 20070101

• Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study.

  BMC gastroenterology 20070101

• Rosai-Dorfman disease: a previously unreported association with sickle cell disease.

  BMC clinical pathology 20070101

• Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray.

  BMC genomics 20070101

• METANNOGEN: compiling features of biochemical reactions needed for the reconstruction of metabolic networks.

  BMC systems biology 20070101

• Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation.

  BMC bioinformatics 20070101

• Pyoderma gangrenosum--a review.

  Orphanet journal of rare diseases 20070101

• A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII.

  Molecular cancer 20070101

• Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis risk.

  Clinical chemistry and laboratory medicine 20070101

• Growth control of the eukaryote cell: a systems biology study in yeast.

  Journal of biology 20070101

• A novel approach for determining cancer genomic breakpoints in the presence of normal DNA.

  PloS one 20070101

• Influence of heating on the activity of xanthine oxidase in tumor cells subjected to the phototoxic action of hematoporphyrin derivative.

  Neoplasma 20070101

• Genome-wide transcriptional plasticity underlies cellular adaptation to novel challenge.

  Molecular systems biology 20070101

• Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.

  Molecular membrane biology 20070101

• Hypoxanthine-guanine phosphoribosyltransferase deficiency: biochemical and molecular findings in six Argentine patients.

  Nucleosides, nucleotides & nucleic acids 20070101

• Selective photo-cross-linking of 2'-O-psoralen-conjugated oligonucleotide with RNAs having point mutations.

  Nucleosides, nucleotides & nucleic acids 20070101

• Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function.

  Scandinavian journal of urology and nephrology 20070101

• Global gene expression analysis and regulation of the principal genes expressed in bovine placenta in relation to the transcription factor AP-2 family.

  Reproductive biology and endocrinology : RB&E 20070101

• Sequence-dependent administration of raloxifene and 5-fluorouracil/pemetrexed protects against pemetrexed cytotoxicity in human bone marrow.

  Anticancer research 20070101

• Diversifying selection and host adaptation in two endosymbiont genomes.

  BMC evolutionary biology 20070101

• Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse.

  PloS one 20070101

• Discovery and characterization of 91 novel transcripts expressed in cattle placenta.

  BMC genomics 20070101

• Effects of AIT-082, a purine derivative, on tremor induced by arecoline or oxotremorine in mice.

  Pharmacology 20070101

• Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in Moroccan population.

  Journal of biomedicine & biotechnology 20070101

• Revealing signaling pathway deregulation by using gene expression signatures and regulatory motif analysis.

  Genome biology 20070101

• Postjunctional synergism of norepinephrine with ATP and diadenosine tetraphosphate in Guinea pig vas deferens. Role of protein kinase C and Myosin light chain phosphatase.

  Pharmacology 20070101

• The crystal structure of Escherichia coli TdcF, a member of the highly conserved YjgF/YER057c/UK114 family.

  BMC structural biology 20070101

• Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.

  BMC biochemistry 20070101

• The Arabidopsis thaliana brassinosteroid receptor (AtBRI1) contains a domain that functions as a guanylyl cyclase in vitro.

  PloS one 20070101

• Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.

  PloS one 20070101

• Regulation of expression and kinetic modeling of substrate interactions of a uracil transporter in Aspergillus nidulans.

  Molecular membrane biology 20070101

• Adenosine arrests apoptosis in lymphocytes but not in phagocytes from primary leucocyte cultures of the teleost fish, Sparus aurata L.

  Developmental and comparative immunology 20070101

• Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.

  Genome biology 20070101

• The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance.

  Nuclear receptor 20070101

• Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.

  Molecular neurodegeneration 20070101

• NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation.

  BMC genomics 20070101

• Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains.

  Genome biology 20070101

• Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice.

  BMC genomics 20070101

• [Treatment of hairy cell leukemia with cladribine].

  Lijecnicki vjesnik 20070101

• Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli.

  BMC microbiology 20070101

• Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger.

  BMC genomics 20070101

• Transcriptome changes and cAMP oscillations in an archaeal cell cycle.

  BMC cell biology 20070101

• Circadian distribution of serum cytokines in multiple sclerosis.

  La Clinica terapeutica 20070101

• A content-centric organization of the genetic code.

  Genomics, proteomics & bioinformatics 20070101

• Identification of genes differentially expressed during larval molting and metamorphosis of Helicoverpa armigera.

  BMC developmental biology 20070101

• Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.

  PloS one 20070101

• Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes.

  BMC cancer 20070101

• Observing metabolic functions at the genome scale.

  Genome biology 20070101

• Correcting for sequence biases in present/absent calls.

  Genome biology 20070101

• The entire organization of transcription units on the Bacillus subtilis genome.

  BMC genomics 20070101

• In silico comparative genomic analysis of GABAA receptor transcriptional regulation.

  BMC genomics 20070101

• Isolation and characterization of human cells resistant to retrovirus infection.

  Retrovirology 20070101

• Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets.

  BMC genomics 20070101

• Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.

  Genome biology 20070101

• Cloning and expression of a zebrafish SCN1B ortholog and identification of a species-specific splice variant.

  BMC genomics 20070101

• Uric acid reduction: a new paradigm in the management of cardiovascular risk?

  Current medicinal chemistry 20070101

• Molecular and functional analysis of hypoxanthine-guanine phosphoribosyltransferase from Arabidopsis thaliana.

  The New phytologist 20070101

• Fludarabine: a review of its use in non-Hodgkin's lymphoma.

  Drugs 20070101

• Identification of modified residues in RNAs by reverse transcription-based methods.

  Methods in enzymology 20070101

• Hairy cell leukemia.

  Medical oncology (Northwood, London, England) 20070101

• Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data.

  BMC bioinformatics 20070101

• Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.

  The international journal of biochemistry & cell biology 20070101

• ISN1 nucleotidases and HAD superfamily protein fold: in silico sequence and structure analysis.

  In silico biology 20070101

• [Effect of warmth-promotion needling on cerebral SOD, MDA and AChE in vascular dementia rats].

  Zhen ci yan jiu = Acupuncture research 20070101

• Hitting bacteria at the heart of the central dogma: sequence-specific inhibition.

  Microbial cell factories 20070101

• Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate.

  BMC genomics 20070101

• Complete deficiency of 5'-nucleotidase activity in Escherichia coli leads to loss of growth on purine nucleotides but not of their excretion.

  Journal of molecular microbiology and biotechnology 20070101

• FDG-PET detection of primary bone marrow large B-cell lymphoma in a patient with hairy cell leukemia.

  Nuclear medicine review. Central & Eastern Europe 20070101

• Engineering a selective small-molecule substrate binding site into a deoxyribozyme.

  Angewandte Chemie (International ed. in English) 20070101

• Naturally occurring and stress induced tubular structures from mammalian cells, a survival mechanism.

  BMC cell biology 20070101

• Induction of apoptosis by alkaloids, non-protein amino acids, and cardiac glycosides in human promyelotic HL-60 cells.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Genome bioinformatic analysis of nonsynonymous SNPs.

  BMC bioinformatics 20070101

• Genome-wide polysomal analysis of a yeast strain with mutated ribosomal protein S9.

  BMC genomics 20070101

• Quantitative analysis of mutation and selection pressures on base composition skews in bacterial chromosomes.

  BMC genomics 20070101

• Efficient construction of an inverted minimal H1 promoter driven siRNA expression cassette: facilitation of promoter and siRNA sequence exchange.

  PloS one 20070101

• Sterility and gene expression in hybrid males of Xenopus laevis and X. muelleri.

  PloS one 20070101

• Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1.

  Microbial cell factories 20070101

• Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery.

  Genome biology 20070101

• Effect of active smoking on the human bronchial epithelium transcriptome.

  BMC genomics 20070101

• AUG_hairpin: prediction of a downstream secondary structure influencing the recognition of a translation start site.

  BMC bioinformatics 20070101

• Automatic generation of 3D motifs for classification of protein binding sites.

  BMC bioinformatics 20070101

• Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes.

  BMC genomics 20070101

• The mitochondrial genome of Phallusia mammillata and Phallusia fumigata (Tunicata, Ascidiacea): high genome plasticity at intra-genus level.

  BMC evolutionary biology 20070101

• Cysteinyl-leukotriene receptors and cellular signals.

  TheScientificWorldJournal 20070101

• Formamide as the main building block in the origin of nucleic acids.

  BMC evolutionary biology 20070101

• The role of gene fusions in the evolution of metabolic pathways: the histidine biosynthesis case.

  BMC evolutionary biology 20070101

• Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus.

  BMC genomics 20070101

• Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein.

  PloS one 20070101

• Metabolome based reaction graphs of M. tuberculosis and M. leprae: a comparative network analysis.

  PloS one 20070101

• EDISA: extracting biclusters from multiple time-series of gene expression profiles.

  BMC bioinformatics 20070101

• Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101

• Ion channel diversity, channel expression and function in the choroid plexuses.

  Cerebrospinal fluid research 20070101

• Environmental variability and modularity of bacterial metabolic networks.

  BMC evolutionary biology 20070101

• Gene discovery and transcript analyses in the corn smut pathogen Ustilago maydis: expressed sequence tag and genome sequence comparison.

  BMC genomics 20070101

• The G protein-coupled receptor subset of the rat genome.

  BMC genomics 20070101

• Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase.

  BMC structural biology 20070101

• Deinococcus geothermalis: the pool of extreme radiation resistance genes shrinks.

  PloS one 20070101

• Dynamic remodelling of synapses can occur in the absence of the parent cell body.

  BMC neuroscience 20070101

• Behavioral genetics and taste.

  BMC neuroscience 20070101

• RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules.

  BMC bioinformatics 20070101

• Abundance and functional diversity of riboswitches in microbial communities.

  BMC genomics 20070101

• Conservation, variability and the modeling of active protein kinases.

  PloS one 20070101

• Genetic subtraction profiling identifies genes essential for Arabidopsis reproduction and reveals interaction between the female gametophyte and the maternal sporophyte.

  Genome biology 20070101

• Understanding the mechanisms of action of methotrexate: implications for the treatment of rheumatoid arthritis.

  Bulletin of the NYU hospital for joint diseases 20070101

• An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report.

  Chiropractic & osteopathy 20070101

• Separate base usages of genes located on the leading and lagging strands in Chlamydia muridarum revealed by the Z curve method.

  BMC genomics 20070101

• [Combination of purine analogues and aminosalicylates in patients with inflammatory bowel disease: why and how?].

  Gastroenterologie clinique et biologique 20070101

• Separating the effects of mutation and selection in producing DNA skew in bacterial chromosomes.

  BMC genomics 20070101

• A new function for the Bacillus PbuE purine base efflux pump: efflux of purine nucleosides.

  Research in microbiology 20070101

• ADAM15 gene structure and differential alternative exon use in human tissues.

  BMC molecular biology 20070101

• Sequences conserved by selection across mouse and human malaria species.

  BMC genomics 20070101

• Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter.

  AIDS research and therapy 20070101

• Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice.

  Journal of Asian natural products research 20070101

• [Effects of mycophenolate mofetil in ischemic acute renal failure in rats].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20070101

• Short sequence motifs, overrepresented in mammalian conserved non-coding sequences.

  BMC genomics 20070101

• [Preliminary results of the effects of electromagnetic fields ELF and TAMMEF on human lymphocytes: evaluation of some biological parameters].

  La Clinica terapeutica 20070101

• Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells.

  Virology journal 20070101

• Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2.

  BMC molecular biology 20070101

• A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient.

  BMC bioinformatics 20070101

• The implications of an incidental chronic lymphocytic leukaemia in a resection specimen for colorectal adenocarcinoma.

  World journal of surgical oncology 20070101

• Recognition of essential purines by the U1A protein.

  BMC biochemistry 20070101

• Myasthenia gravis.

  Orphanet journal of rare diseases 20070101

• Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site.

  BMC structural biology 20070101

• Blood parameters in growing pigs fed increasing levels of bacterial protein meal.

  Acta veterinaria Scandinavica 20070101

• Evolution of temperate pathogens: the bacteriophage/bacteria paradigm.

  Virology journal 20070101

• The distributions, mechanisms, and structures of metabolite-binding riboswitches.

  Genome biology 20070101

• Rapid changes in gene expression dynamics in response to superoxide reveal SoxRS-dependent and independent transcriptional networks.

  PloS one 20070101

• Management of infectious complications in patients with chronic lymphocytic leukemia.

  Hematology. American Society of Hematology. Education Program 20070101

• Property editing of peptide nucleic acids (PNA): gem-dimethyl, cyanuryl and 8-aminoadenine PNAs.

  Nucleic acids symposium series (2004) 20070101

• Functional reactivity of oxanine: its biological meanings and biotechnological applications.

  Nucleic acids symposium series (2004) 20070101

• Location of the triplex DNA-binding domain of Saccharomyces cerevisiae Stm1 protein.

  Nucleic acids symposium series (2004) 20070101

• Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.

  Nucleic acids symposium series (2004) 20070101

• Repair mechanism of DNA-protein cross-link damage in Escherichia coli.

  Nucleic acids symposium series (2004) 20070101

• Syntheses and properties of low-polarity shape mimics of 8-oxopurines.

  Nucleic acids symposium series (2004) 20070101

• Fluorescence emission detection of single-nucleotide polymorphisms by a naphthyridine-benzofurazan conjugate.

  Nucleic acids symposium series (2004) 20070101

• Development of stable DNA microarray platforms suitable for quantitative analysis.

  Nucleic acids symposium series (2004) 20070101

• Enzymatic incorporation of 2-amino-6-vinylpurine derivative.

  Nucleic acids symposium series (2004) 20070101

• In vitro selection of a 5'-purine nucleotide transferase ribozyme.

  Nucleic acids symposium series (2004) 20070101

• Synthesis and evaluation of 9-deazaguanine derivatives as multi-substrate analogue inhibitors of PNP.

  Nucleic acids symposium series (2004) 20070101

• Suppression of subgenomic hepatitis C virus replication by 5'-O-masked analogues of 6-chloropurine-2'-deoxyriboside.

  Nucleic acids symposium series (2004) 20070101

• Comparison of enzymatic recognition of DNA-duplexes containing NO-induced lesions by DNA-relevant enzymes.

  Nucleic acids symposium series (2004) 20070101

• [2,8-dihydroxyadenine nephrolithiasis: from diagnosis to therapy].

  Annales de biologie clinique 20070101

• Age-related subproteomic analysis of mouse liver and kidney peroxisomes.

  Proteome science 20070101

• Proteomic shifts in embryonic stem cells with gene dose modifications suggest the presence of balancer proteins in protein regulatory networks.

  PloS one 20070101

• Gene organization in rice revealed by full-length cDNA mapping and gene expression analysis through microarray.

  PloS one 20070101

• Purinergic (P2) receptor control of lower genitourinary tract function and new avenues for drug action: an overview.

  Current pharmaceutical design 20070101

• Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

  BMC biochemistry 20070101

• Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis.

  BMC bioinformatics 20070101

• The oncoprotein H-RasV12 increases mitochondrial metabolism.

  Molecular cancer 20070101

• An enzymatic transglycosylation of purine bases.

  Nucleosides, nucleotides & nucleic acids 20070101

• Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase.

  Nucleosides, nucleotides & nucleic acids 20070101

• Triplex formation using oligonucleotide clamps carrying 8-aminopurines.

  Nucleosides, nucleotides & nucleic acids 20070101

• Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic versus calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability of human blood lymphocytes.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis study of 2'-O-(2-methoxyethyl)-purine derivatives.

  Nucleosides, nucleotides & nucleic acids 20070101

• Affinity of dinucleotide cap analogues for human decapping scavenger (hDcpS).

  Nucleosides, nucleotides & nucleic acids 20070101

• Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase.

  Nucleosides, nucleotides & nucleic acids 20070101

• Biophysical stability and enzymatic recognition of oxanine in DNA.

  Nucleosides, nucleotides & nucleic acids 20070101

• 2'-deoxyadenosine bearing hydrophobic carborane pharmacophore.

  Nucleosides, nucleotides & nucleic acids 20070101

• Some novel aminopropyl nucleoside phosphonates.

  Nucleosides, nucleotides & nucleic acids 20070101

• Fluorescence studies of calf spleen purine nucleoside phosphorylase (PNP) complexes with guanine and 9-deazaguanine.

  Nucleosides, nucleotides & nucleic acids 20070101

• Interactions of calf spleen purine nucleoside phosphorylase with formycin B and its aglycone - spectroscopic and kinetic studies.

  Nucleosides, nucleotides & nucleic acids 20070101

• Cloning, expression, purification, and some properties of calf purine nucleoside phosphorylase.

  Nucleosides, nucleotides & nucleic acids 20070101

• Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome.

  Orphanet journal of rare diseases 20070101

• Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes.

  Genome biology 20070101

• Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.

  BMC genomics 20070101

• Measurement of cell proliferation by heavy water labeling.

  Nature protocols 20070101

• Measurement of very low rates of cell proliferation by heavy water labeling of DNA and gas chromatography/pyrolysis/isotope ratio-mass spectrometric analysis.

  Nature protocols 20070101

• Restriction site-dependent PCR: an efficient technique for fast cloning of new genes of microorganisms.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20070101

• Profiling sex-biased gene expression during parthenogenetic reproduction in Daphnia pulex.

  BMC genomics 20070101

• Azathioprine in dermatology.

  Acta dermatovenerologica Croatica : ADC 20070101

• Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function.

  Critical reviews in immunology 20070101

• Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.

  Current medicinal chemistry 20070101

• Severe and steroid-resistant Crohn's disease.

  Digestion 20070101

• A scenario on the stepwise evolution of the genetic code.

  Genomics, proteomics & bioinformatics 20070101

• Characterization of copper(II) interactions with sinefungin, a nucleoside antibiotic: combined potentiometric, spectroscopic and DFT studies.

  Bioinorganic chemistry and applications 20070101

• Guanine and inosine nucleotides, nucleosides and oxypurines in snail muscles as potential biomarkers of fluoride toxicity.

  Folia biologica 20070101

• Tumour Lysis Syndrome Occurring in a Patient with Metastatic Gastrointestinal Stromal Tumour Treated with Glivec (Imatinib Mesylate, Gleevec, STI571).

  Sarcoma 20070101

• [Influence of asbestos dust combination with radiation on activity of enzymes involved into purine nucleotides metabolism in various tissues and organs].

  Meditsina truda i promyshlennaia ekologiia 20070101

• Treatment of transformed mycosis fungoides with intermittent low-dose gemcitabine.

  Oncology 20070101

• Complexes of Pd(II) and Pt(II) with 9-aminoacridine: reactions with DNA and study of their antiproliferative activity.

  Bioinorganic chemistry and applications 20070101

• Biochemical studies on the cardioprotective effect of glutamine on tissue antioxidant defense system in isoprenaline-induced myocardial infarction in rats.

  Journal of clinical biochemistry and nutrition 20070101

• Abstracts of papers presented at the 2007 pittsburgh conference.

  Journal of automated methods & management in chemistry 20070101

• The GC skew index: a measure of genomic compositional asymmetry and the degree of replicational selection.

  Evolutionary bioinformatics online 20070101

• Clastogenic factors as potential biomarkers of increased superoxide production.

  Biomarker insights 20070101

• Evaluation of children with urolithiasis.

  Indian journal of urology : IJU : journal of the Urological Society of India 20070101

• Folate during reproduction: the Canadian experience with folic acid fortification.

  Nutrition research and practice 20070101

• Rituximab maintenance in relapsed or refractory follicular non-Hodgkin's lymphoma: the evidence of its therapeutic value.

  Core evidence 20070101

• Infliximab: the evidence for its place in therapy in ulcerative colitis.

  Core evidence 20070101

• Modulation of visceral nociception, inflammation and gastric mucosal injury by cinnarizine.

  Drug target insights 20070101

• Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.

  Drug target insights 20070101

• Cysteine-scanning analysis of the nucleobase-ascorbate transporter signature motif in YgfO permease of Escherichia coli: Gln-324 and Asn-325 are essential, and Ile-329-Val-339 form an alpha-helix.

  The Journal of biological chemistry 20061229

• 2-Aminopurine inhibits leptin receptor signal transduction.

  European journal of pharmacology 20061228

• Interaction of low-energy electrons with the purine bases, nucleosides, and nucleotides of DNA.

  The Journal of chemical physics 20061228

• Complexed structures of formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima describe a novel ATP binding protein superfamily.

  Biochemistry 20061219

• Enzymatic assay of allantoin in serum using allantoinase and allantoate amidohydrolase.

  Analytical biochemistry 20061215

• Strain differences in the responsiveness between Sprague-Dawley and Fischer rats to nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.

  Toxicology and applied pharmacology 20061215

• Electronic structure of DNA nucleobases and their dinucleotides explored by soft X-ray spectroscopy.

  The journal of physical chemistry. A 20061214

• Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.

  Journal of medicinal chemistry 20061214

• Surface-enhanced Raman spectroscopy (SERS) for sub-micromolar detection of DNA/RNA mononucleotides.

  Journal of the American Chemical Society 20061213

• Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle.

  Cell death and differentiation 20061201

• Modification of p53 protein profile by gamma irradiation followed by methyl donor starvation.

  Molecular and cellular biochemistry 20061201

• Characterization of the rat Na+/nucleoside cotransporter 2 and transport of nucleoside-derived drugs using electrophysiological methods.

  American journal of physiology. Cell physiology 20061201

• Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.

  Planta 20061201

• Synthesis, X-ray crystal structural study, antiviral and cytostatic evaluations of the novel unsaturated acyclic and epoxide nucleoside analogues.

  Bioorganic & medicinal chemistry 20061201

• Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site.

  Bioorganic & medicinal chemistry 20061201

• Metabolic design of macroscopic bioreaction models: application to Chinese hamster ovary cells.

  Bioprocess and biosystems engineering 20061201

• Metabolic functions of glycosomes in trypanosomatids.

  Biochimica et biophysica acta 20061201

• A purine at +2 rather than +1 adjacent to the human U6 promoter is required to prepare effective short hairpin RNAs.

  Biochemical and biophysical research communications 20061201

• Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein.

  Journal of biochemistry 20061201

• On the hypothesis that the failing heart is energy starved: lessons learned from the metabolism of ATP and creatine.

  Current hypertension reports 20061201

• Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue.

  Chembiochem : a European journal of chemical biology 20061201

• Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma.

  Expert opinion on investigational drugs 20061201

• The substrate specificity of tRNA (m1G37) methyltransferase (TrmD) from Aquifex aeolicus.

  Genes to cells : devoted to molecular & cellular mechanisms 20061201

• Crystallization and preliminary X-ray analysis of human MTH1 complexed with two oxidized nucleotides, 8-oxo-dGMP and 2-oxo-dATP.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20061201

• An efficient method for homologous gene reconstitution in Cryptococcus gattii using URA5 auxotrophic marker.

  Mycopathologia 20061201

• Changes in membrane conductance play a pathogenic role in osmotic glial cell swelling in detached retinas.

  The American journal of pathology 20061201

• Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells.

  Leukemia & lymphoma 20061201

• Computational reconstruction of iron- and manganese-responsive transcriptional networks in alpha-proteobacteria.

  PLoS computational biology 20061201

• NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site.

  PLoS pathogens 20061201

• Dynamics of the cellular metabolome during human cytomegalovirus infection.

  PLoS pathogens 20061201

• Role of immunochemotherapy in the treatment of chronic lymphocytic leukemia.

  Expert review of anticancer therapy 20061201

• Configuration of a scintillation proximity assay for the activity assessment of recombinant human adenine phosphoribosyltransferase.

  Assay and drug development technologies 20061201

• Pathogenesis, clinical findings and management of acute and chronic gout.

  Minerva medica 20061201

• Sprint training reduces urinary purine loss following intense exercise in humans.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20061201

• [Perspectives in clinical immunology].

  Recenti progressi in medicina 20061201

• In vivo engineering of proteins with nitrogen-containing tryptophan analogs.

  Applied microbiology and biotechnology 20061201

• Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia.

  The Yale journal of biology and medicine 20061201

• Hydration of mononucleotides.

  Journal of the American Chemical Society 20061129

• Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase.

  The Journal of biological chemistry 20061124

• Simple synthesis of some pentafluoropropenyl derivatives of pyrimidine and purine based on addition-elimination reaction.

  The Journal of organic chemistry 20061110

• Regiospecific N9 alkylation of 6-(heteroaryl)purines: shielding of N7 by a proximal heteroaryl C-H1.

  The Journal of organic chemistry 20061110

• Modified pyrimidines specifically bind the purine riboswitch.

  Journal of the American Chemical Society 20061108

• C4' sugar oxidation of deoxyribonucleotide triphosphates by chromium(V) complexes.

  Mutation research 20061107

• pH-Independent triplex formation: hairpin DNA containing isoguanine or 9-deaza-9-propynylguanine in place of protonated cytosine.

  Organic & biomolecular chemistry 20061107

• Comparative studies on Ureide Permeases in Arabidopsis thaliana and analysis of two alternative splice variants of AtUPS5.

  Planta 20061101

• Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha.

  International journal of cancer 20061101

• Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects.

  Blood 20061101

• A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs.

  Molecular pharmacology 20061101

• Nucleotides and inorganic phosphates as potential antioxidants.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20061101

• Interactions of 1,12-diamino-4,9-dioxadodecane (OSpm) and Cu(II) ions with pyrimidine and purine nucleotides: adenosine-5'-monophosphate (AMP) and cytidine-5'-monophosphate (CMP).

  Journal of inorganic biochemistry 20061101

• Cladribine therapy in refractory celiac disease with aberrant T cells.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101

• Induction of A.T to G.C mutations by erroneous repair of depurinated DNA following estrogen treatment of the mammary gland of ACI rats.

  The Journal of steroid biochemistry and molecular biology 20061101

• Clofarabine and nelarabine: two new purine nucleoside analogs.

  Current opinion in oncology 20061101

• Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity.

  Mutagenesis 20061101

• Adenosine and cytokine levels following treatment of rheumatoid arthritis with dipyridamole.

  Rheumatology international 20061101

• Origin of informational polymers: The concurrent roles of formamide and phosphates.

  Chembiochem : a European journal of chemical biology 20061101

• Regulation of purine nucleotide biosynthesis: in yeast and beyond.

  Biochemical Society transactions 20061101

• Implementing tandem mass spectrometry as a routine tool for characterizing the complete purine and pyrimidine metabolic profile in urine samples.

  Journal of mass spectrometry : JMS 20061101

• Atlantoaxial subluxation with recurrent consciousness disturbance in a boy with Lesch-Nyhan syndrome.

  Acta paediatrica (Oslo, Norway : 1992) 20061101

• Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break.

  Radiation research 20061101

• SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks.

  Acta tropica 20061101

• Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.

  PLoS biology 20061101

• [Killing effect of PNP/MeP-dR suicide gene system driven by an AFP promoter AF0.3 on AFP-positive hepatoma cells].

  Ai zheng = Aizheng = Chinese journal of cancer 20061101

• Target DNA structure plays a critical role in RAG transposition.

  PLoS biology 20061101

• 2-CdA in the treatment of hairy cell leukemia: a review of long-term follow-up.

  Leukemia & lymphoma 20061101

• Chronic lymphocytic leukemia: current and emerging treatment approaches.

  Clinical advances in hematology & oncology : H&O 20061101

• First joint italian-german purine club meeting 'progress in purinergic receptor pharmacology and function'.

  Purinergic signalling 20061101

• Roles of P2 receptors in glial cells: focus on astrocytes.

  Purinergic signalling 20061101

• Signal transduction events induced by extracellular guanosine 5' triphosphate in excitable cells.

  Purinergic signalling 20061101

• Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes.

  Purinergic signalling 20061101

• Non-adenine based purines accelerate wound healing.

  Purinergic signalling 20061101

• Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II).

  Purinergic signalling 20061101

• Multiple determinants influence root colonization and induction of induced systemic resistance by Pseudomonas chlororaphis O6.

  Molecular plant pathology 20061101

• Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction.

  Molecules and cells 20061031

• Tautomerism in the guanyl radical.

  Journal of the American Chemical Society 20061025

• Diagnosing AICA-ribosiduria by capillary electrophoresis.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020

• Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides.

  Bioorganic & medicinal chemistry letters 20061015

• Heavy smoking and liver.

  World journal of gastroenterology 20061014

• Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter.

  Journal of molecular biology 20061013

• ATP-consuming and ATP-generating enzymes secreted by pancreas.

  The Journal of biological chemistry 20061006

• Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity.

  Journal of medicinal chemistry 20061005

• 9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.

  Journal of medicinal chemistry 20061005

• ATP potentiates neurotransmission in the rat trigeminal subnucleus caudalis.

  Neuroreport 20061002

• TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice.

  The Journal of clinical investigation 20061002

• Trypanosoma brucei: a survey of pyrimidine transport activities.

  Experimental parasitology 20061001

• Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro.

  Antiviral research 20061001

• EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).

  Annals of the rheumatic diseases 20061001

• P2Y1 receptors mediate inhibitory purinergic neuromuscular transmission in the human colon.

  American journal of physiology. Gastrointestinal and liver physiology 20061001

• Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells.

  Blood 20061001

• The paperclip triplex: understanding the role of apex residues in tight turns.

  Biophysical journal 20061001

• Adenosine kinase from Cryptosporidium parvum.

  Molecular and biochemical parasitology 20061001

• Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma.

  Cancer 20061001

• Genotoxic effects in C57Bl/6J mice chronically exposed to arsenate in drinking water and modulation of the effects by low-selenium diet.

  Journal of toxicology and environmental health. Part A 20061001

• The response of gastrointestinal microbiota to avilamycin, butyrate, and plant extracts in early-weaned pigs.

  Journal of animal science 20061001

• Cladribine: an investigational immunomodulatory agent for multiple sclerosis.

  The Annals of pharmacotherapy 20061001

• Clinical presentations and complications of hairy cell leukemia.

  Hematology/oncology clinics of North America 20061001

• Splenectomy, interferon, and treatments of historical interest in hairy cell leukemia.

  Hematology/oncology clinics of North America 20061001

• Purine analogues: rationale for development, mechanisms of action, and pharmacokinetics in hairy cell leukemia.

  Hematology/oncology clinics of North America 20061001

• Pentostatin: impact on outcome in hairy cell leukemia.

  Hematology/oncology clinics of North America 20061001

• Cladribine in hairy cell leukemia.

  Hematology/oncology clinics of North America 20061001

• Immunotoxins in the treatment of refractory hairy cell leukemia.

  Hematology/oncology clinics of North America 20061001

• Hairy cell leukemia: towards a curative strategy.

  Hematology/oncology clinics of North America 20061001

• Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.

  Arthritis and rheumatism 20061001

• Drug evaluation: forodesine - PNP inhibitor for the treatment of leukemia, lymphoma and solid tumor.

  IDrugs : the investigational drugs journal 20061001

• Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.

  Cancer research 20061001

• Back to the beginnings: an autobiography.

  Transfusion medicine reviews 20061001

• Cytokine-purine interactions in traumatic stress, behavioral depression, and sickness.

  CNS & neurological disorders drug targets 20061001

• External proficiency testing programmes in laboratory diagnoses of inherited metabolic disorders.

  Annals of the Academy of Medicine, Singapore 20061001

• A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes.

  Journal of enzyme inhibition and medicinal chemistry 20061001

• Narrative review: initial management of newly diagnosed, early-stage chronic lymphocytic leukemia.

  Annals of internal medicine 20060919

• Time-resolved photoelectron and photoion fragmentation spectroscopy study of 9-methyladenine and its hydrates: a contribution to the understanding of the ultrafast radiationless decay of excited DNA bases.

  Physical chemistry chemical physics : PCCP 20060914

• Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates.

  Journal of medicinal chemistry 20060907

• 5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase.

  Journal of medicinal chemistry 20060907

• Symptomatic hypoglycemia: an unusual side effect of oral purine analogues for treatment of ALL.

  Pediatric blood & cancer 20060901

• Characterization of T-cell repertoire in hairy cell leukemia patients before and after recombinant immunotoxin BL22 therapy.

  Cancer immunology, immunotherapy : CII 20060901

• Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation.

  Journal of cellular biochemistry 20060901

• Activity and expression of ecto-5'-nucleotidase/CD73 are increased by thyroid hormones in vascular smooth muscle cells.

  Molecular and cellular biochemistry 20060901

• Metabolism and ecology of purine alkaloids.

  Frontiers in bioscience : a journal and virtual library 20060901

• The transthyretin-related protein: structural investigation of a novel protein family.

  Journal of structural biology 20060901

• Synthesis and biological evaluation of carboacyclic nucleosides with (Z) and (E)-9-[4,4-bis(hydroxymethyl)]-2-butenyl side chain.

  Bioorganic & medicinal chemistry 20060901

• Purine release from spinal cord microglia after elevation of calcium by glutamate.

  Molecular pharmacology 20060901

• Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog.

  The Journal of biological chemistry 20060901

• Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase.

  Neuroscience research 20060901

• Biotransformation of adenine and cytokinins by the rhizobacterium Serratia proteamaculans.

  Phytochemistry 20060901

• Gene expression for enzymes and transporters involved in regulating adenosine and inosine levels in rat forebrain neurons, astrocytes and C6 glioma cells.

  Journal of neuroscience research 20060901

• Crystal structure of a non-discriminating glutamyl-tRNA synthetase.

  Journal of molecular biology 20060901

• Effects of dairy cow diet forage proportion on duodenal nutrient supply and urinary purine derivative excretion.

  Journal of dairy science 20060901

• Azathioprine in dermatology: the past, the present, and the future.

  Journal of the American Academy of Dermatology 20060901

• Investigating the caffeine effects in the yeast Saccharomyces cerevisiae brings new insights into the connection between TOR, PKC and Ras/cAMP signalling pathways.

  Molecular microbiology 20060901

• Alcohol consumption as a trigger of recurrent gout attacks.

  The American journal of medicine 20060901

• Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.

  ChemMedChem 20060901

• Tris(1,9-diethyladeninium) triiodide diiodide.

  Acta crystallographica. Section C, Crystal structure communications 20060901

• Designing siRNA that distinguish between genes that differ by a single nucleotide.

  PLoS genetics 20060901

• Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.

  Molecular cancer therapeutics 20060901

• Update on risk-stratified management for chronic lymphocytic leukemia.

  Leukemia & lymphoma 20060901

• Treatment of recurrent Langerhans cell histiocytosis in children with 2-chlorodeoxyadenosine.

  Leukemia & lymphoma 20060901

• Energetics of the failing heart: new insights using genetic modification in the mouse.

  Archives des maladies du coeur et des vaisseaux 20060901

• P2X7 receptor expression levels determine lethal effects of a purine based danger signal in T lymphocytes.

  Cellular immunology 20060901

• Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia.

  International journal of nanomedicine 20060901

• Plant responses to extracellular nucleotides: Cellular processes and biological effects.

  Purinergic signalling 20060901

• Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks.

  Purinergic signalling 20060901

• P2 receptors in atherosclerosis and postangioplasty restenosis.

  Purinergic signalling 20060901

• Increased 5-HT(3)-mediated signalling in pelvic afferent neurons from mice deficient in P2X(2) and/or P2X (3) receptor subunits.

  Purinergic signalling 20060901

• Excitatory effect of ATP on rat area postrema neurons.

  Purinergic signalling 20060901

• Nelarabine: a new purine analog in the treatment of hematologic malignancies.

  Reviews on recent clinical trials 20060901

• Changes of purine and pyrimidine nucleotide biosynthesis during shoot initiation from epicotyl explants of white spruce (Picea glauca).

  Plant science : an international journal of experimental plant biology 20060901

• Protein dynamics and catalysis: the problems of transition state theory and the subtlety of dynamic control.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060829

• Antitumor agents. 5. synthesis, structure-activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5h-benzopyridophenoxazin-5-ones, and 5h-benzopyridophenoxazin-5-ones with potent antiproliferative activity.

  Journal of medicinal chemistry 20060824

• Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells.

  British journal of cancer 20060821

• The neglected Pt-N(sulfonamido) bond in Pt chemistry. New fluorophore-containing Pt(II) complexes useful for assessing Pt(II) interactions with biomolecules.

  Inorganic chemistry 20060821

• Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms.

  The Journal of biological chemistry 20060818

• C6-substituted analogues of 8-azanebularine: probes of an RNA-editing enzyme active site.

  Organic letters 20060817

• The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production.

  Bioorganic & medicinal chemistry letters 20060815

• Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors.

  Bioorganic & medicinal chemistry 20060815

• Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents.

  Bioorganic & medicinal chemistry letters 20060815

• H-bonding-directed self-assembly of synthetic copolymers containing nucleobases: organization and colloidal fusion in a noncompetitive solvent.

  Langmuir : the ACS journal of surfaces and colloids 20060815

• The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal.

  Journal of molecular medicine (Berlin, Germany) 20060801

• A survey of mRNA sequences with a non-AUG start codon in RefSeq database.

  Journal of biomolecular structure & dynamics 20060801

• Current treatment options in hairy cell leukemia and hairy cell leukemia variant.

  Cancer treatment reviews 20060801

• AUG-proximal nucleotides regulate protein synthesis in Leishmania tropica.

  Molecular microbiology 20060801

• Single-agent purine analogues for the treatment of chronic lymphocytic leukaemia: a systematic review and meta-analysis.

  Cancer treatment reviews 20060801

• Nucleoside transporters: from scavengers to novel therapeutic targets.

  Trends in pharmacological sciences 20060801

• Comparative proteomic analysis of Staphylococcus aureus strains with differences in resistance to the cell wall-targeting antibiotic vancomycin.

  Proteomics 20060801

• The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn.

  Journal of immunology (Baltimore, Md. : 1950) 20060801

• Mutational analysis of the promoter recognized by Chlamydia and Escherichia coli sigma(28) RNA polymerase.

  Journal of bacteriology 20060801

• Enhanced separation of purine and pyrimidine bases using carboxylic multiwalled carbon nanotubes as additive in capillary zone electrophoresis.

  Electrophoresis 20060801

• Vitamin B12 reduces ribavirin-induced genotoxicity in phytohemaglutinin-stimulated human lymphocytes.

  The Tohoku journal of experimental medicine 20060801

• Fludarabine in chronic lymphocytic leukaemia.

  Expert opinion on pharmacotherapy 20060801

• [Synthetic study of nucleoside antibiotics].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060801

• Bioinformatic analysis of Helicobacter pylori XGPRTase: a potential therapeutic target.

  Helicobacter 20060801

• Chronic lymphocytic leukemia: diagnosis and treatment.

  Mayo Clinic proceedings 20060801

• Proteomic analysis of protein expression in Streptococcus pneumoniae in response to temperature shift.

  Journal of microbiology (Seoul, Korea) 20060801

• Hairy-cell leukaemia: first-line treatment with cladribine or pentostatin.

  Prescrire international 20060801

• [Advances in the study of nucleoside antiviral drugs].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060801

• Nucleotide-mimetic synthetic ligands for DNA-recognizing enzymes One-step purification of Pfu DNA polymerase.

  Journal of chromatography. A 20060728

• Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli.

  Mutation research 20060725

• Purine antagonists for chronic lymphocytic leukaemia.

  The Cochrane database of systematic reviews 20060719

• Amplified oligonucleotide sensing in microliter volumes containing copper ions by solution streaming.

  Analytical chemistry 20060715

• Activation of the purine salvage pathway in mononuclear cells of cardiac recipients treated with mycophenolate mofetil.

  Transplantation 20060715

• Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation.

  The Journal of biological chemistry 20060714

• MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.

  DNA repair 20060713

• Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase.

  The Journal of biological chemistry 20060707

• Post-reperfusion myocardial infarction: long-term survival improvement using adenosine regulation with acadesine.

  Journal of the American College of Cardiology 20060704

• Mycophenolate mofetil is a highly effective and safe immunosuppressive agent for the treatment of uveitis : a retrospective analysis of 106 patients.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060701

• Symbiotic abilities of Sinorhizobium fredii with modified expression of purL.

  Applied microbiology and biotechnology 20060701

• Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.

  American journal of physiology. Gastrointestinal and liver physiology 20060701

• Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages.

  Molecular and biochemical parasitology 20060701

• Deoxyribonucleic acid damage and spontaneous mutagenesis in the thyroid gland of rats and mice.

  Endocrinology 20060701

• Oxidative stress and heat-shock responses in Desulfovibrio vulgaris by genome-wide transcriptomic analysis.

  Antonie van Leeuwenhoek 20060701

• Recent diuretic use and the risk of recurrent gout attacks: the online case-crossover gout study.

  The Journal of rheumatology 20060701

• Purine-induced expression of urate oxidase and enzyme activity in Atlantic salmon (Salmo salar). Cloning of urate oxidase liver cDNA from three teleost species and the African lungfish Protopterus annectens.

  The FEBS journal 20060701

• Long-term mizoribine intermittent pulse therapy for young patients with flare of lupus nephritis.

  Pediatric nephrology (Berlin, Germany) 20060701

• Acute renal failure due to bilateral xanthine urolithiasis in a boy with Lesch-Nyhan syndrome.

  Pediatric nephrology (Berlin, Germany) 20060701

• Cell biology of molybdenum.

  Biochimica et biophysica acta 20060701

• Molecular simulations of cotranslational protein folding: fragment stabilities, folding cooperativity, and trapping in the ribosome.

  PLoS computational biology 20060701

• Bis(6-thioxo-1,6-dihydropurinium) tetrachlorozincate(II).

  Acta crystallographica. Section C, Crystal structure communications 20060701

• Different nucleobase orientations in two cyclic 2',3'-phosphates of purine ribonucleosides: Et(3)NH(2',3'-cAMP) and Et(3)NH(2',3'-cGMP)xH(2)O.

  Acta crystallographica. Section C, Crystal structure communications 20060701

• Interrelationship between uremic toxicity and oxidative stress.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20060701

• Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal.

  Environmental health perspectives 20060701

• Circadian rhythmicity by autocatalysis.

  PLoS computational biology 20060701

• Targeting Hsp90 for the treatment of cancer.

  Current opinion in drug discovery & development 20060701

• Reduced-intensity transplantation for lymphoma.

  Current treatment options in oncology 20060701

• Fine-tuning modulation of myenteric motoneurons by endogenous adenosine: on the role of secreted adenosine deaminase.

  Autonomic neuroscience : basic & clinical 20060630

• The crystal structure of the transthyretin-like protein from Salmonella dublin, a prokaryote 5-hydroxyisourate hydrolase.

  Journal of molecular biology 20060623

• Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets.

  Journal of theoretical biology 20060621

• Phosphate activation in the ground state of purine nucleoside phosphorylase.

  Journal of the American Chemical Society 20060621

• Thermodynamics of the purine nucleotide cycle.

  Biophysical chemistry 20060620

• Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III.

  Biochemistry 20060620

• Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers.

  British journal of cancer 20060619

• The purines: potent and versatile small molecule inhibitors and modulators of key biological targets.

  Bioorganic & medicinal chemistry 20060615

• DNA and LNA oligonucleotides containing N2'-functionalised derivatives of 2'-amino-2'-deoxyuridine.

  Bioorganic & medicinal chemistry letters 20060615

• Effect of various pyrimidines possessing the 1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl] moiety, able to mimic natural 2'-deoxyribose, on wild-type and mutant hepatitis B virus replication.

  Journal of medicinal chemistry 20060615

• GENTEX, a general multiscale model for in vivo tissue exchanges and intraorgan metabolism.

  Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20060615

• Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety.

  Biochemical pharmacology 20060614

• A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.

  The Journal of biological chemistry 20060609

• Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.

  Journal of molecular biology 20060609

• C5'-adenosinyl radical cyclization. A stereochemical investigation.

  The Journal of organic chemistry 20060609

• Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines.

  Organic & biomolecular chemistry 20060607

• Transition state analogue discrimination by related purine nucleoside phosphorylases.

  Journal of the American Chemical Society 20060607

• Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control.

  British journal of cancer 20060605

• Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.

  Journal of molecular biology 20060602

• Purification and characterization of a novel mammalian endoribonuclease.

  Journal of cellular biochemistry 20060601

• In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes.

  Molecular and biochemical parasitology 20060601

• Involvement of adenosine in the neurobiology of schizophrenia and its therapeutic implications.

  Progress in neuro-psychopharmacology & biological psychiatry 20060601

• Comprehensive detection of disorders of purine and pyrimidine metabolism by HPLC with electrospray ionization tandem mass spectrometry.

  Clinical chemistry 20060601

• Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20060601

• Structures of regulatory elements in mRNAs.

  Current opinion in structural biology 20060601

• Biomarkers signal contaminant effects on the organs of English sole (Parophrys vetulus) from Puget Sound.

  Environmental health perspectives 20060601

• Withdrawal. Changes in purine metabolism and production of oxygen free radicals by intermittent partial umbilical cord occlusion in chronically instrumented fetal lambs.

  The journal of obstetrics and gynaecology research 20060601

• Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains.

  Biotechnology letters 20060601

• Parametric alignment of Drosophila genomes.

  PLoS computational biology 20060601

• Derivation and characterization of a monoclonal antibody against human glycinamide ribonucleotide formyltransferase.

  Hybridoma (2005) 20060601

• [Molecular cloning and expression analysis of swamp eel (Monopterus albus) Hprt].

  Yi chuan = Hereditas 20060601

• Involvement of LuxR, a quorum sensing regulator in Vibrio harveyi, in the promotion of metabolic genes: argA, purM, lysE and rluA.

  Biochimica et biophysica acta 20060601

• New developments in the epidemiology and genetics of gout.

  Current rheumatology reports 20060601

• Ecto-5'-nucleotidase: Structure function relationships.

  Purinergic signalling 20060601

• Physiological roles for ecto-5'-nucleotidase (CD73).

  Purinergic signalling 20060601

• Modulation of purinergic signaling by NPP-type ectophosphodiesterases.

  Purinergic signalling 20060601

• E-NTPDases in human airways: Regulation and relevance for chronic lung diseases.

  Purinergic signalling 20060601

• The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance.

  Purinergic signalling 20060601

• Expressed sequence tag (EST) analysis of the erythrocytic stages of Babesia bovis.

  Veterinary parasitology 20060531

• The extraordinary specificity of xanthine phosphoribosyltransferase from Bacillus subtilis elucidated by reaction kinetics, ligand binding, and crystallography.

  Biochemistry 20060530

• The transmembrane domain provides nucleotide binding specificity to the bacterial conjugation protein TrwB.

  FEBS letters 20060529

• A general synthesis of C6-azolyl purine nucleosides.

  Angewandte Chemie (International ed. in English) 20060526

• Structure and synthesis of 6-(substituted-imidazol-1-yl)purines: versatile substrates for regiospecific alkylation and glycosylation at N9.

  The Journal of organic chemistry 20060526

• Interaction energies for the purine inhibitor roscovitine with cyclin-dependent kinase 2: correlated ab initio quantum-chemical, DFT and empirical calculations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060524

• 2,6-disubstituted and 2,6,8-trisubstituted purines as adenosine receptor antagonists.

  Journal of medicinal chemistry 20060518

• Purine and folate metabolism as a potential target of sex-specific nutrient allocation in Drosophila and its implication for lifespan-reproduction tradeoff.

  Physiological genomics 20060516

• Role of the Cys18-Cys274 disulfide bond and of the third extracellular loop in the constitutive activation and internalization of angiotensin II type 1 receptor.

  Regulatory peptides 20060515

• Microanalysis of oligodeoxynucleotides by cathodic stripping voltammetry at amalgam-alloy surfaces in the presence of copper ions.

  Talanta 20060515

• The lack of A2A adenosine receptors diminishes the reinforcing efficacy of cocaine.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060501

• Control by cytokinins of the cellular behavior in the plate meristem of zucchini cotyledons.

  Planta 20060501

• Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine.

  International journal of cancer 20060501

• Characterization of novel Na+-dependent nucleobase transport systems at the blood-testis barrier.

  American journal of physiology. Endocrinology and metabolism 20060501

• Postnatal development of P2 receptors in the murine gastrointestinal tract.

  Neuropharmacology 20060501

• DNA tracts composed of only two bases concentrate in gene promoters.

  Genomics 20060501

• Suboptimal CD4 gains in HIV-infected patients receiving didanosine plus tenofovir.

  The Journal of antimicrobial chemotherapy 20060501

• Genotoxicity of chloroquine in rat liver cells: protective role of free radical scavengers.

  Cell biology and toxicology 20060501

• Delineation of the motor disorder of Lesch-Nyhan disease.

  Brain : a journal of neurology 20060501

• Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.

  RNA (New York, N.Y.) 20060501

• New agents in chronic lymphocytic leukemia.

  Current treatment options in oncology 20060501

• Caffeine biosynthesis and adenine metabolism in transgenic Coffea canephora plants with reduced expression of N-methyltransferase genes.

  Phytochemistry 20060501

• Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1.

  Molecular microbiology 20060501

• Probing the mechanism of purine nucleoside phosphorylase by steady-state kinetic studies and ligand binding characterization determined by fluorimetric titrations.

  Biochimica et biophysica acta 20060501

• Expression, purification, crystallization and preliminary X-ray diffraction analysis of human phosphoribosyl pyrophosphate synthetase 1 (PRS1).

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060501

• [Efficacy of rituximab in hairy cell leukemia].

  Presse medicale (Paris, France : 1983) 20060501

• Iterative reconstruction of transcriptional regulatory networks: an algorithmic approach.

  PLoS computational biology 20060501

• Pharmacological and clinical studies on purine nucleoside analogs--new anticancer agents.

  Mini reviews in medicinal chemistry 20060501

• The purine metabolism of human erythrocytes.

  Biochemistry. Biokhimiia 20060501

• Nitrogenous compounds of interest in clinical nutrition.

  Nutricion hospitalaria 20060501

• The effect of acidosis on adenosine release from cultured rat forebrain neurons.

  Brain research 20060412

• Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis-trans epimerization.

  DNA repair 20060408

• Schwann cells in rat vascular autonomic nerves activated via purinergic receptors.

  Neuroreport 20060403

• MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

  Cell death and differentiation 20060401

• Trypanosoma cruzi: Mutations in the 3' untranslated region of calmodulin gene are specific for lineages T. cruzi I, T. cruzi II, and the Zymodeme III isolates.

  Experimental parasitology 20060401

• O6-(4-bromothenyl)guanine (PaTrin-2), a novel inhibitor of O6-alkylguanine DNA alkyl-transferase, increases the inhibitory activity of temozolomide against human acute leukaemia cells in vitro.

  Pharmacological research 20060401

• Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060401

• AtAAH encodes a protein with allantoate amidohydrolase activity from Arabidopsis thaliana.

  Planta 20060401

• Solution structure of an informationally complex high-affinity RNA aptamer to GTP.

  RNA (New York, N.Y.) 20060401

• Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060401

• Mitochondrial uncoupling proteins: new insights from functional and proteomic studies.

  Free radical biology & medicine 20060401

• Purine analogue combinations for indolent lymphomas.

  Seminars in hematology 20060401

• Pentostatin for the treatment of indolent lymphoproliferative disorders.

  Seminars in hematology 20060401

• Role of single-agent purine analogues in therapy of peripheral T-cell lymphomas.

  Seminars in hematology 20060401

• Purine analogues in advanced T-cell lymphoid malignancies.

  Seminars in hematology 20060401

• The role of purine analogues in low-intensity regimens with allogeneic hematopoietic stem cell transplantation.

  Seminars in hematology 20060401

• Purine analogue-based chemotherapy regimens for second-line therapy in patients with chronic lymphocytic leukemia.

  Seminars in hematology 20060401

• Purine analogue-based chemotherapy regimens for patients with previously untreated B-chronic lymphocytic leukemia.

  Seminars in hematology 20060401

• Genes encoding ribonucleoside hydrolase 1 and 2 from Corynebacterium ammoniagenes.

  Microbiology (Reading, England) 20060401

• Pentostatin and purine analogs for indolent lymphoid malignancies.

  Future oncology (London, England) 20060401

• Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060401

• Reaction mechanisms of riboflavin triplet state with nucleic acid bases.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060401

• Linkage analysis with an interbreed backcross maps Dalmatian hyperuricosuria to CFA03.

  Mammalian genome : official journal of the International Mammalian Genome Society 20060401

• Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.

  Biological chemistry 20060401

• Autoimmune complications of chronic lymphocytic leukemia.

  Seminars in oncology 20060401

• Infectious complications of chronic lymphocytic leukemia.

  Seminars in oncology 20060401

• Practical strategies for discovering regulatory DNA sequence motifs.

  PLoS computational biology 20060401

• Novel therapeutic strategies with alemtuzumab for chronic lymphocytic leukemia.

  Seminars in oncology 20060401

• Strategies in the management of alemtuzumab-related side effects.

  Seminars in oncology 20060401

• Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro.

  Cellular immunology 20060401

• A novel-type substrate-selectivity filter and ER-exit determinants in the UapA purine transporter.

  Journal of molecular biology 20060331

• Selective magnesiation of chloro-iodopurines: an efficient approach to new purine derivatives.

  Organic letters 20060330

• Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases.

  Cancer letters 20060328

• Consecutive GA pairs stabilize medium-size RNA internal loops.

  Biochemistry 20060328

• The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum.

  The Journal of biological chemistry 20060324

• Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases.

  Organic & biomolecular chemistry 20060321

• Fluorescence energy transfer studies of human deoxycytidine kinase: role of cysteine 185 in the conformational changes that occur upon substrate binding.

  Biochemistry 20060321

• Structure of purine-purine mispairs during misincorporation and extension by Escherichia coli DNA polymerase I.

  Biochemistry 20060321

• The crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase II from Sulfolobus solfataricus, a thermophilic enzyme stabilized by intramolecular disulfide bonds.

  Journal of molecular biology 20060317

• Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication.

  Bioorganic & medicinal chemistry letters 20060315

• Nucleotide-binding sites in the voltage-dependent anion channel: characterization and localization.

  The Journal of biological chemistry 20060303

• Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes.

  The Journal of organic chemistry 20060303

• Monitoring of antioxidant properties of uric acid in humans for a consideration measuring of levels of allantoin in plasma by liquid chromatography.

  Clinica chimica acta; international journal of clinical chemistry 20060301

• Genetic manipulation of two fowlpox virus late transcriptional regulatory elements influences their ability to direct expression of foreign genes.

  Virus research 20060301

• Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors.

  Bioorganic & medicinal chemistry 20060301

• Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.

  The Biochemical journal 20060301

• The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development.

  Molecular endocrinology (Baltimore, Md.) 20060301

• Pharmacologic characterization of intrinsic mechanisms controlling tone and relaxation of porcine lower esophageal sphincter.

  The Journal of pharmacology and experimental therapeutics 20060301

• The purine synthesis gene Prat2 is required for Drosophila metamorphosis, as revealed by inverted-repeat-mediated RNA interference.

  Genetics 20060301

• Molecular, biochemical, and genetic characterization of a female patient with Lesch-Nyhan disease.

  Molecular genetics and metabolism 20060301

• Intense exercise induces the degradation of adenine nucleotide and purine nucleotide synthesis via de novo pathway in the rat liver.

  European journal of applied physiology 20060301

• Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis.

  Journal of leukocyte biology 20060301

• Determination of acid-base dissociation constants of amino- and guanidinopurine nucleotide analogs and related compounds by capillary zone electrophoresis.

  Electrophoresis 20060301

• Uric acid crystals in the semen of a patient with symptoms of chronic prostatitis.

  Fertility and sterility 20060301

• Advances in the treatment of Waldenström's macroglobulinemia.

  Expert review of anticancer therapy 20060301

• Treatment of gastric mucosa-associated lymphoid tissue lymphoma: Helicobacter pylori eradication and beyond.

  Expert review of anticancer therapy 20060301

• Pathophysiology and therapeutic potential of purinergic signaling.

  Pharmacological reviews 20060301

• Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex.

  Genes & development 20060301

• Genome update: purine strand bias in 280 bacterial genomes.

  Microbiology (Reading, England) 20060301

• Pentose phosphates in nucleoside interconversion and catabolism.

  The FEBS journal 20060301

• Human cytochrome P450 reductase can act as a source of endogenous oxidative DNA damage and genetic instability.

  Free radical biology & medicine 20060301

• Gemcitabine and atrial fibrillation: a rare manifestation of chemotherapy toxicity.

  Anti-cancer drugs 20060301

• Integration of ruminal metabolism in dairy cattle.

  Journal of dairy science 20060301

• Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity.

  Structure (London, England : 1993) 20060301

• [Correlations between serine hydroxymethyltransferase1 C1420T polymorphisms and susceptibilities to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma].

  Ai zheng = Aizheng = Chinese journal of cancer 20060301

• A third approach to gene prediction suggests thousands of additional human transcribed regions.

  PLoS computational biology 20060301

• Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation.

  Chemical research in toxicology 20060301

• Synthesis and antiviral evaluation of novel open-chain analogues of neplanocin A.

  Nucleosides, nucleotides & nucleic acids 20060301

• Effects of allopurinol on beer-induced increases in plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine).

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060301

• Advances in the treatment of chronic lymphocytic leukemia.

  Current hematologic malignancy reports 20060301

• Evaluation of urinary abnormalities in nephrolithiasis patients from Marathwada region.

  Indian journal of clinical biochemistry : IJCB 20060301

• A clinical assessment of direct electrochemical urate measurements.

  Talanta 20060227

• 1,3-Alternate 25,27-dibenzoiloxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel as a new type of HPLC stationary phase.

  Talanta 20060227

• Bacterial small-molecule signaling pathways.

  Science (New York, N.Y.) 20060224

• Heroin affects purine nucleotides catabolism in rats in vivo.

  Life sciences 20060223

• Supramolecular architectures assembled by the interaction of purine nucleobases with metal-oxalato frameworks. Non-covalent stabilization of the 7H-adenine tautomer in the solid-state.

  Dalton transactions (Cambridge, England : 2003) 20060221

• Platinum(II)-mediated coupling reactions of acetonitrile with the exocyclic nitrogen of 9-methyladenine and 1-methylcytosine. Synthesis, NMR characterization, and X-ray structures of new azametallacycle complexes.

  Inorganic chemistry 20060220

• Improved HPLC method for the simultaneous determination of allantoin, uric acid and creatinine in cattle urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217

• Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma.

  The Journal of biological chemistry 20060217

• Effect of allopurinol on brain adenosine levels during hypoxia in newborn piglets.

  Brain research 20060216

• How I treat refractory CLL.

  Blood 20060215

• Synthesis and biological evaluation of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides.

  Bioorganic & medicinal chemistry 20060215

• Stochastic entropy QSAR for the in silico discovery of anticancer compounds: prediction, synthesis, and in vitro assay of new purine carbanucleosides.

  Bioorganic & medicinal chemistry 20060215

• Structural investigation of bilayers formed by 1-palmitoyl-2-oleoylphosphatidylnucleosides.

  Biophysical journal 20060215

• Unique properties of purine/pyrimidine asymmetric PNA.DNA duplexes: differential stabilization of PNA.DNA duplexes by purines in the PNA strand.

  Biophysical journal 20060215

• The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats.

  European journal of pharmacology 20060215

• MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060208

• Sequence dependence of the stability of RNA hairpin molecules with six nucleotide loops.

  Biochemistry 20060207

• Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP.

  Journal of molecular biology 20060203

• Synthesis and conformational analysis of new cyclobutane-fused nucleosides.

  Organic letters 20060202

• Plant uncoupling protein in mitochondria from aged-dehydrated slices of Jerusalem artichoke tubers becomes sensitive to superoxide and to hydrogen peroxide without increase in protein level.

  Biochimie 20060201

• Thymosin beta4 induces a conformational change in actin monomers.

  Biophysical journal 20060201

• Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme.

  Molecular genetics and genomics : MGG 20060201

• Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation.

  British journal of pharmacology 20060201

• Zinc(II) complexes with potent cyclin-dependent kinase inhibitors derived from 6-benzylaminopurine: synthesis, characterization, X-ray structures and biological activity.

  Journal of inorganic biochemistry 20060201

• Immunophenotypic variations in hairy cell leukemia.

  American journal of clinical pathology 20060201

• Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution.

  Acta crystallographica. Section D, Biological crystallography 20060201

• Effects of malate on diet digestibility, microbial protein synthesis, plasma metabolites, and performance of growing lambs fed a high-concentrate diet.

  Journal of animal science 20060201

• Transformation and progression of Waldenström's macroglobulinemia following cladribine therapy in two cases: natural evolution or iatrogenic causation?

  American journal of hematology 20060201

• Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs.

  Microbiology (Reading, England) 20060201

• Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives.

  Molecular and cellular biochemistry 20060201

• Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma.

  Fundamental & clinical pharmacology 20060201

• Activation of P2Y receptor enhances high-molecular compound absorption from rat ileum.

  The Journal of pharmacy and pharmacology 20060201

• [Spicamycin derivative].

  Nihon rinsho. Japanese journal of clinical medicine 20060201

• NMR structures of damaged DNA.

  Chemical reviews 20060201

• Heterologous expression of membrane and soluble proteins derepresses GCN4 mRNA translation in the yeast Saccharomyces cerevisiae.

  Eukaryotic cell 20060201

• Clinical experience with pemetrexed in breast cancer.

  Seminars in oncology 20060201

• Ratiometric fluorescence detection of pyrimidine/purine transversion by using a 2-amino-1,8-naphthyridine derivative.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060201

• [Urinary stone disease indicating genetic background].

  Nihon rinsho. Japanese journal of clinical medicine 20060201

• T-cell activation via CD26 and caveolin-1 in rheumatoid synovium.

  Modern rheumatology 20060201

• Isolation and characterization of promoters from Lactococcus lactis ssp. cremoris LM0230.

  Food microbiology 20060201

• NMR imino proton exchange experiments on duplex DNA primarily monitor the opening of purine bases.

  Journal of the American Chemical Society 20060125

• Insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase.

  The journal of physical chemistry. A 20060119

• Benzoderivatives of nucleic acid bases as modified DNA building blocks.

  The journal of physical chemistry. A 20060119

• Ground-state interactions of spermine-substituted naphthalimides with mononucleotides.

  The journal of physical chemistry. B 20060119

• Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells.

  British journal of cancer 20060116

• Two- and three-dimensional quantitative structure-activity relationships for a series of purine nucleoside phosphorylase inhibitors.

  Bioorganic & medicinal chemistry 20060115

• A retrospective comparison of three sequential groups of patients with Recurrent/Refractory chronic lymphocytic leukemia treated with fludarabine-based regimens.

  Cancer 20060115

• Uncoupling protein 1 affects the yeast mitoproteome and oxygen free radical production.

  Free radical biology & medicine 20060115

• Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.

  European journal of pharmacology 20060113

• 7-Functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose.

  The Journal of organic chemistry 20060106

• N6-Cyclohexyl-adenosine but not adenosine is a modulator of teleost fish innate immune activities.

  Developmental and comparative immunology 20060101

• Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs.

  Biology of the neonate 20060101

• A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.

  Molecular pharmacology 20060101

• Metabolic homeostasis in the human erythrocyte: in silico analysis.

  Bio Systems 20060101

• Transition state analysis of adenosine nucleosidase from yellow lupin (Lupinus luteus).

  Phytochemistry 20060101

• Update on ureide degradation in legumes.

  Journal of experimental botany 20060101

• Effect of long-term phosphate starvation on the levels and metabolism of purine nucleotides in suspension-cultured Catharanthus roseus cells.

  Phytochemistry 20060101

• Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise.

  Metabolism: clinical and experimental 20060101

• Conserved and variable functions of the sigmaE stress response in related genomes.

  PLoS biology 20060101

• Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes.

  Journal of neurochemistry 20060101

• Concomitant hairy cell and acute myeloid leukemia.

  European journal of haematology 20060101

• A folate-dependent metabolite in amniotic fluid from pregnancies with normal or trisomy 21 chromosomes.

  Fetal diagnosis and therapy 20060101

• Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase.

  Arthritis research & therapy 20060101

• Combining infliximab with methotrexate for the induction and maintenance of remission in refractory Crohn's disease: a controlled pilot study.

  European journal of gastroenterology & hepatology 20060101

• The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro.

  Investigational new drugs 20060101

• Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

  PLoS biology 20060101

• Design and cloning strategies for constructing shRNA expression vectors.

  BMC biotechnology 20060101

• Early-onset autoimmune hemolytic anemia after cladribine therapy for Waldenström's macroglobulinemia.

  Transfusion 20060101

• Analysis of and function predictions for previously conserved hypothetical or putative proteins in Blochmannia floridanus.

  BMC microbiology 20060101

• Chronic lymphocytic leukemia: recent advances in diagnosis and treatment.

  The oncologist 20060101

• Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

  Nature chemical biology 20060101

• Metabolic pathways variability and sequence/networks comparisons.

  BMC bioinformatics 20060101

• Effects of a fenofibrate/losartan combination on the plasma concentration and urinary excretion of purine bases.

  International journal of clinical pharmacology and therapeutics 20060101

• Effect and mechanism of total saponin of Dioscorea on animal experimental hyperuricemia.

  The American journal of Chinese medicine 20060101

• Identification of metabolic system parameters using global optimization methods.

  Theoretical biology & medical modelling 20060101

• Fludarabine induced autoimmune haemolytic anaemia in a patient with chronic lymphocytic leukaemia.

  JPMA. The Journal of the Pakistan Medical Association 20060101

• BIOZON: a system for unification, management and analysis of heterogeneous biological data.

  BMC bioinformatics 20060101

• Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.

  Chemical biology & drug design 20060101

• Abnormal turning behaviour, GABAergic inhibition and the degeneration of astrocytes in ovine Tribulus terrestris motor neuron disease.

  Australian veterinary journal 20060101

• Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae.

  BMC genomics 20060101

• Integrating protein structures and precomputed genealogies in the Magnum database: examples with cellular retinoid binding proteins.

  BMC bioinformatics 20060101

• Hypoxanthine as a graft ischemia marker stimulates catalase activity in the renal vein during reperfusion in humans.

  Transplantation proceedings 20060101

• A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones.

  Genome biology 20060101

• Challenging the spliceosome machine.

  Genome biology 20060101

• Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks.

  BMC genomics 20060101

• New agents for the treatment of acute myeloid leukemia.

  Best practice & research. Clinical haematology 20060101

• Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis.

  Arthritis research & therapy 20060101

• [ADP-ribose and cADP-ribose--endogenous regulators of cellular ionic balance. Cardiotropic effects of ADP-ribose].

  Uspekhi fiziologicheskikh nauk 20060101

• Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms.

  BMC bioinformatics 20060101

• Microbial identification by mass cataloging.

  BMC bioinformatics 20060101

• Recognition and activation of ryanodine receptors by purines.

  Current medicinal chemistry 20060101

• Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.

  BMC medical genetics 20060101

• Asymptomatic bacteriuria in sickle cell disease: a cross-sectional study.

  BMC infectious diseases 20060101

• Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells.

  BMC developmental biology 20060101

• DNA deformability changes of single base pair mutants within CDE binding sites in S. Cerevisiae centromere DNA correlate with measured chromosomal loss rates and CDE binding site symmetries.

  BMC molecular biology 20060101

• Development of an unbiased statistical method for the analysis of unigenic evolution.

  BMC bioinformatics 20060101

• Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics.

  BMC evolutionary biology 20060101

• An application of statistics to comparative metagenomics.

  BMC bioinformatics 20060101

• Amino acid size, charge, hydropathy indices and matrices for protein structure analysis.

  Theoretical biology & medical modelling 20060101

• [The usefulness of adenosine deaminase determination in biological fluids for tuberculosis diagnosis].

  Annales de biologie clinique 20060101

• The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression.

  Cancer cell international 20060101

• Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture.

  Cerebrospinal fluid research 20060101

• Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock.

  BMC bioinformatics 20060101

• Specific age-related signatures in Drosophila body parts transcriptome.

  BMC genomics 20060101

• Whitefly (Bemisia tabaci) genome project: analysis of sequenced clones from egg, instar, and adult (viruliferous and non-viruliferous) cDNA libraries.

  BMC genomics 20060101

• The complete plastid genome sequence of the parasitic green alga Helicosporidium sp. is highly reduced and structured.

  BMC biology 20060101

• Partial HPRT deficiency (Kelley-Seegmiller syndrome).

  The Journal of the Association of Physicians of India 20060101

• Molybdenum cofactor biosynthesis and molybdenum enzymes.

  Annual review of plant biology 20060101

• Pyrimidine and purine biosynthesis and degradation in plants.

  Annual review of plant biology 20060101

• High-throughput screening of cellulase F mutants from multiplexed plasmid sets using an automated plate assay on a functional proteomic robotic workcell.

  Proteome science 20060101

• Determining the structural basis for specificity of ligands using crystallographic screening.

  Cell biochemistry and biophysics 20060101

• Reactive oxygen species: role in the development of cancer and various chronic conditions.

  Journal of carcinogenesis 20060101

• [Current views about the role of purin metabolism disorders in patients with arterial hypertension and losartan potentialities].

  Kardiologiia 20060101

• A nucleolar localizing Rev binding element inhibits HIV replication.

  AIDS research and therapy 20060101

• Phylogeny based discovery of regulatory elements.

  BMC bioinformatics 20060101

• The physiological regulation of uncoupling proteins.

  Biochimica et biophysica acta 20060101

• A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank.

  BMC evolutionary biology 20060101

• Gene expression in cortex and hippocampus during acute pneumococcal meningitis.

  BMC biology 20060101

• Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.

  BMC molecular biology 20060101

• Pyrite-induced hydroxyl radical formation and its effect on nucleic acids.

  Geochemical transactions 20060101

• Free radical theory of autoimmunity.

  Theoretical biology & medical modelling 20060101

• Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing.

  BMC neuroscience 20060101

• The Yersinia pestis gcvB gene encodes two small regulatory RNA molecules.

  BMC microbiology 20060101

• Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags.

  BMC genomics 20060101

• Uncoupling proteins: a role in protection against reactive oxygen species--or not?

  Biochimica et biophysica acta 20060101

• Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights.

  Photochemistry and photobiology 20060101

• Recent advances in chronic lymphocytic leukemia.

  Cancer investigation 20060101

• [Hairy cell leukemia: prognosis and treatment].

  La Clinica terapeutica 20060101

• A concise history of gout and hyperuricemia and their treatment.

  Arthritis research & therapy 20060101

• Epidemiology, risk factors, and lifestyle modifications for gout.

  Arthritis research & therapy 20060101

• Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.

  Arthritis research & therapy 20060101

• Stem-loop structures in prokaryotic genomes.

  BMC genomics 20060101

• Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma.

  World journal of surgical oncology 20060101

• Analysis of RNA splicing defects in PITX2 mutants supports a gene dosage model of Axenfeld-Rieger syndrome.

  BMC medical genetics 20060101

• Selective inhibition of the human tie-1 promoter with triplex-forming oligonucleotides targeted to Ets binding sites.

  Molecular medicine (Cambridge, Mass.) 20060101

• Structural property of DNA that migrates faster in gel electrophoresis, as deduced by CD spectroscopy.

  Nucleosides, nucleotides & nucleic acids 20060101

• Recognition of oxidized thymine base on the single-stranded DNA by replication protein A.

  Nucleosides, nucleotides & nucleic acids 20060101

• Apoptotic effect of ganciclovir on primary effusion lymphoma cells infected with Kaposi's sarcoma-associated herpesvirus.

  Nucleosides, nucleotides & nucleic acids 20060101

• Synthesis and biological properties of new phosmidosine analogs having an N-acylsulfamate linkage.

  Nucleosides, nucleotides & nucleic acids 20060101

• Adenylosuccinate lyase deficiency.

  Molecular genetics and metabolism 20060101

• The purinome, a complex mix of drug and toxicity targets.

  Current topics in medicinal chemistry 20060101

• Targeting cancer: the challenges and successes of structure-based drug design against the human purinome.

  Current topics in medicinal chemistry 20060101

• Association of poly-purine/poly-pyrimidine sequences with meiotic recombination hot spots.

  BMC genomics 20060101

• MANET: tracing evolution of protein architecture in metabolic networks.

  BMC bioinformatics 20060101

• Design principles of molecular networks revealed by global comparisons and composite motifs.

  Genome biology 20060101

• Water-elutability of nucleic acids from metal-chelate affinity adsorbents: enhancement by control of surface charge density.

  Journal of molecular recognition : JMR 20060101

• Alkaline fluid circulation in ultramafic rocks and formation of nucleotide constituents: a hypothesis.

  Geochemical transactions 20060101

• Analysis of Nanoarchaeum equitans genome and proteome composition: indications for hyperthermophilic and parasitic adaptation.

  BMC genomics 20060101

• Transient change in GABA(A) receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration.

  BMC neuroscience 20060101

• Identification of new participants in the rainbow trout (Oncorhynchus mykiss) oocyte maturation and ovulation processes using cDNA microarrays.

  Reproductive biology and endocrinology : RB&E 20060101

• Recently published papers: dying Swans and other stories.

  Critical care (London, England) 20060101

• Identification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2.

  BMC microbiology 20060101

• Hairy cell leukemia: an elusive but treatable disease.

  The oncologist 20060101

• Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases.

  Journal of biomedicine & biotechnology 20060101

• Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells.

  Respiratory research 20060101

• Antiproliferative and proapoptotic activities of pyranoxanthenones, pyranothioxanthenones and their pyrazole-fused derivatives in HL-60 cells.

  Anticancer research 20060101

• Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss).

  BMC genomics 20060101

• Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway.

  BMC genomics 20060101

• Synthesis of 2'-amino-LNA purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20060101

• A preventive approach to oral self-mutilation in Lesch-Nyhan syndrome: a case report.

  Pediatric dentistry 20060101

• [The effect of modification of tRNA nucleotide-37 on the tRNA interaction with the P- and A-site of the 70S ribosome Escherichia coli].

  Molekuliarnaia biologiia 20060101

• In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators.

  Kinetoplastid biology and disease 20060101

• Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae.

  BMC bioinformatics 20060101

• Transcriptional and structural impact of TATA-initiation site spacing in mammalian core promoters.

  Genome biology 20060101

• Comparative kinetic analysis of AzgA and Fcy21p, prototypes of the two major fungal hypoxanthine-adenine-guanine transporter families.

  Molecular membrane biology 20060101

• The first transmembrane segment (TMS1) of UapA contains determinants necessary for expression in the plasma membrane and purine transport.

  Molecular membrane biology 20060101

• Fast index based algorithms and software for matching position specific scoring matrices.

  BMC bioinformatics 20060101

• [Genetically determined gout: characteristics of the course].

  TSitologiia i genetika 20060101

• Virulence properties of cariogenic bacteria.

  BMC oral health 20060101

• Cri du Chat syndrome.

  Orphanet journal of rare diseases 20060101

• Serum adenosine deaminase activity in monitoring disease activity and response to therapy in severe psoriasis.

  Acta medica (Hradec Kralove) 20060101

• Renal lithiasis and nutrition.

  Nutrition journal 20060101

• Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model.

  BMC developmental biology 20060101

• Amdoxovir versus placebo with enfuvirtide plus optimized background therapy for HIV-1-infected subjects failing current therapy (AACTG A5118).

  Antiviral therapy 20060101

• Uncoupling proteins, dietary fat and the metabolic syndrome.

  Nutrition & metabolism 20060101

• When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation.

  Molecular systems biology 20060101

• The complete mitochondrial genome of a basal teleost, the Asian arowana (Scleropages formosus, Osteoglossidae).

  BMC genomics 20060101

• LIGSITEcsc: predicting ligand binding sites using the Connolly surface and degree of conservation.

  BMC structural biology 20060101

• Comparative assessment of performance and genome dependence among phylogenetic profiling methods.

  BMC bioinformatics 20060101

• Multiple opportunistic infections after high-dose steroid therapy for giant cell arteritis in a patient previously treated with a purine analog.

  Scandinavian journal of infectious diseases 20060101

• Immunosuppressive drugs in HIV disease.

  Current topics in medicinal chemistry 20060101

• Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review.

  Molecular cancer 20060101

• A study of the purine derivative AIT-082 in G93A SOD1 transgenic mice.

  International journal of immunopathology and pharmacology 20060101

• Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition.

  BMC cancer 20060101

• The TGF-beta1/upstream stimulatory factor-regulated PAI-1 gene: potential involvement and a therapeutic target in Alzheimer's disease.

  Journal of biomedicine & biotechnology 20060101

• Oxidative damage to RNA in neurodegenerative diseases.

  Journal of biomedicine & biotechnology 20060101

• Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs.

  Journal of biomedicine & biotechnology 20060101

• An enhanced RNA alignment benchmark for sequence alignment programs.

  Algorithms for molecular biology : AMB 20060101

• Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design.

  BMC structural biology 20060101

• Purine and pyrimidine metabolism: a firm basis for a transformed society.

  Nucleosides, nucleotides & nucleic acids 20060101

• Familial juvenile hyperuricaemic nephropathy is not such a rare genetic metabolic purine disease in Britain.

  Nucleosides, nucleotides & nucleic acids 20060101

• Efficacy and safety of allopurinol in patients with the Lesch-Nyhan syndrome and partial hypoxanthine- phosphoribosyltransferase deficiency: a follow-up study of 18 Spanish patients.

  Nucleosides, nucleotides & nucleic acids 20060101

• Effect of beer ingestion on the plasma concentrations and urinary excretion of purine bases: one-month study.

  Nucleosides, nucleotides & nucleic acids 20060101

• Differences in activities of the enzymes of nucleotide metabolism and its implications for cardiac xenotransplantation.

  Nucleosides, nucleotides & nucleic acids 20060101

• Synthesis and mass spectrometric fragmentation characteristics of imidazole ribosides-analogs of intermediates of purine de novo synthetic pathway.

  Nucleosides, nucleotides & nucleic acids 20060101

• 5 '-Amino-4-imidazolecarboxamide riboside induces apoptosis in human neuroblastoma cells via the mitochondrial pathway.

  Nucleosides, nucleotides & nucleic acids 20060101

• Purine metabolism in B-cell lymphocytic leukemia: a microarray approach.

  Nucleosides, nucleotides & nucleic acids 20060101

• Purine metabolism and clinical status of patients with rheumatoid arthritis treated with dipyridamole.

  Nucleosides, nucleotides & nucleic acids 20060101

• Purine catabolism in advanced carotid artery plaque.

  Nucleosides, nucleotides & nucleic acids 20060101

• Analysis of excretion fraction of uric acid.

  Nucleosides, nucleotides & nucleic acids 20060101

• An unusual cause of renal amyloidosis secondary to gout: the first description of familial occurrence.

  Nucleosides, nucleotides & nucleic acids 20060101

• Microwave-assisted ring closure reactions: synthesis of 8-substituted xanthine derivatives and related pyrimido- and diazepinopurinediones.

  Beilstein journal of organic chemistry 20060101

• Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors.

  Nucleosides, nucleotides & nucleic acids 20060101

• Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats.

  BMC gastroenterology 20060101

• An improved and highly sensitive microfluorimetric method for assessing susceptibility of Plasmodium falciparum to antimalarial drugs in vitro.

  Malaria journal 20060101

• Cytokinins inhibit epiphyllous plantlet development on leaves of Bryophyllum (Kalanchoë) marnierianum.

  Journal of experimental botany 20060101

• BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments.

  Genome biology 20060101

• Pathway-specific differences between tumor cell lines and normal and tumor tissue cells.

  Molecular cancer 20060101

• Adenosine deaminase from camel tick Hyalomma dromedarii: purification and characterization.

  Experimental & applied acarology 20060101

• Critical roles of glutamine as nitrogen donors in purine and pyrimidine nucleotide synthesis: asparaginase treatment in childhood acute lymphoblastic leukemia.

  In vivo (Athens, Greece) 20060101

• Huntingtin gene evolution in Chordata and its peculiar features in the ascidian Ciona genus.

  BMC genomics 20060101

• The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.

  Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20060101

• Cyclin-dependent kinase (CDK) inhibitor olomoucine enhances gamma-irradiation-induced apoptosis and cell cycle arrest in Raji cells.

  Anticancer research 20060101

• Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans.

  Genome biology 20060101

• Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

  Malaria journal 20060101

• Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells.

  Molecular cancer 20060101

• Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (kidney) and non-target (liver) tissues in rats.

  BMC bioinformatics 20060101

• Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers.

  BMC genomics 20060101

• Immune hemolytic anemia--selected topics.

  Hematology. American Society of Hematology. Education Program 20060101

• CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo.

  Journal of biology 20060101

• Targeting of toxic compounds to the trypanosome's interior.

  Advances in parasitology 20060101

• Mechanisms of genotoxin-induced transcription and hypermutation in p53.

  Cancer cell international 20060101

• Ethanol sensitivity: a central role for CREB transcription regulation in the cerebellum.

  BMC genomics 20060101

• In silico experimentation with a model of hepatic mitochondrial folate metabolism.

  Theoretical biology & medical modelling 20060101

• A strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides.

  Nucleic acids symposium series (2004) 20060101

• Synthesis of 2',4'-BNACOC bearing a purine nucleobase.

  Nucleic acids symposium series (2004) 20060101

• Structural property and enzymatic response of oxanine in DNA strands.

  Nucleic acids symposium series (2004) 20060101

• Anti-SARS-CoV activity of nucleoside analogs having 6-chloropurine as a nucleobase.

  Nucleic acids symposium series (2004) 20060101

• Development of novel PRODAN-labeled nucleosides as base-discriminating fluorescent probes.

  Nucleic acids symposium series (2004) 20060101

• Effects of the modified aromatic ring of WNA on stability of triplex DNA.

  Nucleic acids symposium series (2004) 20060101

• Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity.

  Current medicinal chemistry 20060101

• Ligands for A2B adenosine receptor subtype.

  Current medicinal chemistry 20060101

• A computational analysis of the three isoforms of glutamate dehydrogenase reveals structural features of the isoform EC 1.4.1.4 supporting a key role in ammonium assimilation by plants.

  Biology direct 20060101

• Transcription profile of a human breast cancer cell line expressing MMTV-like sequences.

  Infectious agents and cancer 20060101

• Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays.

  Molecular cancer 20060101

• Mariner mutagenesis of Brucella melitensis reveals genes with previously uncharacterized roles in virulence and survival.

  BMC microbiology 20060101

• Role of pyrite in formation of hydroxyl radicals in coal: possible implications for human health.

  Particle and fibre toxicology 20060101

• Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis.

  Proteome science 20060101

• Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis.

  BMC genomics 20060101

• Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12 beta-glucosidase.

  BMC plant biology 20060101

• Structures, mechanism, regulation and evolution of class III nucleotidyl cyclases.

  Reviews of physiology, biochemistry and pharmacology 20060101

• [Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays].

  Radiatsionnaia biologiia, radioecologiia 20060101

• Structural studies of the purine and SAM binding riboswitches.

  Cold Spring Harbor symposia on quantitative biology 20060101

• New Dihydro OO'Bis(Salicylidene) 2,2' Aminobenzothiazolyl Borate Complexes: Kinetic and Voltammetric Studies of Dimethyltin Copper Complex with Guanine, Adenine, and Calf Thymus DNA.

  Bioinorganic chemistry and applications 20060101

• Changes in plasma concentrations of hypoxanthine and xanthine in renal vein as an index of delayed kidney allograft function.

  Urology journal 20060101

• Modeling of phosphomethyl pyrimidine kinase from Leptospira interrogans serovar lai strain 56601.

  Bioinformation 20060101

• Functional annotation of hypothetical proteins - A review.

  Bioinformation 20060101

• Insight into gene fusion from molecular dynamics simulation of fused and un-fused IGPS (Imidazole Glycerol Phosphate Synthetase).

  Bioinformation 20060101

• Older and new formulations of cladribine. Pharmacology and clinical efficacy in hematological malignancies.

  Recent patents on anti-cancer drug discovery 20060101

• Recent clinical trials of cladribine in hematological malignancies and autoimmune disorders.

  Reviews on recent clinical trials 20060101

• A nuclear ribosomal DNA phylogeny of acer inferred with maximum likelihood, splits graphs, and motif analysis of 606 sequences.

  Evolutionary bioinformatics online 20060101

• Structure of homeodomain-leucine zipper/DNA complexes studied using hydroxyl radical cleavage of DNA and methylation interference.

  Biochemistry 20051227

• Facile preparation of the oxetane-nucleosides.

  Organic & biomolecular chemistry 20051221

• Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase.

  Biochemistry 20051220

• Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

  Biochemical pharmacology 20051219

• 6-Benzylthioinosine analogues: promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es).

  Biochemical pharmacology 20051219

• Inverting the charges of natural nucleobase quartets: a planar platinum-purine quartet with pronounced sulfate affinity.

  Angewandte Chemie (International ed. in English) 20051216

• A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).

  Blood 20051215

• Differential effect of insulin and elevated glucose level on adenosine handling in rat T lymphocytes.

  Journal of cellular biochemistry 20051215

• Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase.

  Bioorganic & medicinal chemistry 20051215

• Tacrolimus-induced alopecia in female kidney-pancreas transplant recipients.

  Transplantation 20051215

• The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.

  British journal of cancer 20051212

• Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats.

  Mutation research 20051211

• The leukocyte count predicts the efficacy of treatment with azathioprine in inflammatory bowel disease.

  European journal of medical research 20051207

• Experimental therapy of allogeneic solid tumors induced in athymic mice with suicide gene-transducing replication-competent foamy virus vectors.

  Cancer gene therapy 20051201

• Selective anti-tubercular purines: synthesis and chemotherapeutic properties of 6-aryl- and 6-heteroaryl-9-benzylpurines.

  Bioorganic & medicinal chemistry 20051201

• Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20051201

• Long remissions in hairy cell leukemia with purine analogs: a report of 219 patients with a median follow-up of 12.5 years.

  Cancer 20051201

• The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K.

  Nature biotechnology 20051201

• Acute pancreatitis in patients with Crohn's disease: clinical features and outcomes.

  Inflammatory bowel diseases 20051201

• Changes in the natural history of progressive multifocal leukoencephalopathy in HIV-negative lymphoproliferative disorders: impact of novel therapies.

  American journal of hematology 20051201

• An evaluation of pemetrexed in second-line treatment of non-small cell lung cancer.

  Expert opinion on pharmacotherapy 20051201

• Phase I study of low-dose interleukin-2, fludarabine, and cyclophosphamide for previously untreated indolent lymphoma and chronic lymphocytic leukemia.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051201

• The Systemic Theory of Living Systems. Part IV: Systemic Medicine--The Praxis.

  Evidence-based complementary and alternative medicine : eCAM 20051201

• Substrate specificity of vaccinia virus thymidylate kinase.

  The FEBS journal 20051201

• Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers.

  Molecular cancer therapeutics 20051201

• Toxoplasma gondii: localization of purine nucleoside phosphorylase activity in vitro and in vivo by electron microscopy.

  Medical molecular morphology 20051201

• Inosine infusion prevents mortality in endotoxic shock.

  The Journal of trauma 20051201

• Strand displacement of double-stranded DNA by triplex-forming antiparallel purine-hairpins.

  Oligonucleotides 20051201

• [Genetic testing and gene-based testing for hyperuricemia and gout].

  Nihon rinsho. Japanese journal of clinical medicine 20051201

• Harnessing natural diversity to probe metabolic pathways.

  PLoS genetics 20051201

• Bolus injection of adenosine before cardioplegic induction improves postischemic global function in coronary artery bypass grafting.

  Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20051201

• [Epidemiology of infections in neutropenic patients].

  Enfermedades infecciosas y microbiologia clinica 20051201

• Microbiologic consequences of new approaches to managing hematologic malignancies.

  Reviews in clinical and experimental hematology 20051201

• Editorial.

  Purinergic signalling 20051201

• First joint Italian-German purine club meeting 'Progress in Purinergic Receptor Pharmacology and Function'.

  Purinergic signalling 20051201

• ATP release via anion channels.

  Purinergic signalling 20051201

• Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2.

  Purinergic signalling 20051201

• The priming effect of extracellular UTP on human neutrophils: Role of calcium released from thapsigargin-sensitive intracellular stores.

  Purinergic signalling 20051201

• Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates.

  Biochemistry 20051129

• Crystal structure of a purine/pyrimidine phosphoribosyltransferase-related protein from Thermus thermophilus HB8.

  Proteins 20051115

• Polymer supported carbodiimide strategy for the synthesis of N-acylated derivatives of deoxy- and ribo purinenucleosides using active esters.

  Bioorganic & medicinal chemistry letters 20051115

• A trans acting ribozyme that phosphorylates exogenous RNA.

  Biochemistry 20051115

• Size-expanded DNA bases: an ab initio study of their structural and electronic properties.

  The journal of physical chemistry. B 20051110

• Binding of 5'-GMP to the GluR2 AMPA receptor: insight from targeted molecular dynamics simulations.

  Biochemistry 20051108

• Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B.

  Biochemistry 20051108

• 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.

  Journal of medicinal chemistry 20051103

• A Golgi study of neuronal architecture in a genetic mouse model for Lesch-Nyhan disease.

  Neurobiology of disease 20051101

• Role of 5'-nucleotidase in thiopurine metabolism: enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment.

  Clinica chimica acta; international journal of clinical chemistry 20051101

• Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy.

  FEMS microbiology reviews 20051101

• Effects of azathioprine and its metabolites on repair mechanisms of the intestinal epithelium in vitro.

  Regulatory peptides 20051101

• In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability.

  Journal of neurochemistry 20051101

• Synthesis, spectral study and cytotoxicity of platinum(II) complexes with 2,9-disubstituted-6-benzylaminopurines.

  Journal of inorganic biochemistry 20051101

• Mutational analysis of the Bacillus subtilis purA operator site.

  Current microbiology 20051101

• Like cops on the beat: the active role of resting microglia.

  Trends in neurosciences 20051101

• Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy.

  Clinical chemistry 20051101

• 3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence.

  Mutagenesis 20051101

• New developments in the diagnosis, prognosis and treatment of chronic lymphocytic leukemia.

  Current opinion in oncology 20051101

• Effect of abomasal pectin infusion on digestion and nitrogen balance in lactating dairy cows.

  Journal of dairy science 20051101

• Comparison of four markers for quantifying microbial protein flow from the rumen of lactating dairy cows.

  Journal of dairy science 20051101

• Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.

  Acta crystallographica. Section D, Biological crystallography 20051101

• Identification of three urease accessory proteins that are required for urease activation in Arabidopsis.

  Plant physiology 20051101

• Identification of Arabidopsis salt and osmotic stress responsive proteins using two-dimensional difference gel electrophoresis and mass spectrometry.

  Proteomics 20051101

• Personal exposure to ultrafine particles and oxidative DNA damage.

  Environmental health perspectives 20051101

• Reduced thymic output, increased spontaneous apoptosis and oligoclonal B cells in polyethylene glycol-adenosine deaminase-treated patients.

  European journal of immunology 20051101

• Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20051101

• Understanding treatments for gout.

  The American journal of managed care 20051101

• Determination of 13C CSA tensors: extension of the model-independent approach to an RNA kissing complex undergoing anisotropic rotational diffusion in solution.

  Journal of biomolecular NMR 20051101

• [High intestinal transport activity for nucleosides in cattle: a synopsis].

  DTW. Deutsche tierarztliche Wochenschrift 20051101

• [Effects of exogenerous nucleotides on the apoptosis of intestinal epithelial cells IEC-6].

  Wei sheng yan jiu = Journal of hygiene research 20051101

• Pyrazolo[4,3-e][1,2,4]triazines: purine analogues with electronic absorption in the visible region.

  Molecules (Basel, Switzerland) 20051031

• Purine activity of RNase T1RV is further improved by substitution of Trp59 by tyrosine.

  Biochemical and biophysical research communications 20051028

• Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis.

  Journal of molecular biology 20051028

• Design and evaluation of dihydroxytetrahydro-1H-pyrrolo[2,1-c]- [1,4]benzothiazines as conformationally restricted transition-state inhibitors of beta-ribosidases.

  The Journal of organic chemistry 20051028

• Simple ethers as models of sugar molecules in calculations of vertical excitation energies of DNA and RNA nucleosides.

  The journal of physical chemistry. A 20051027

• Correlation between strand asymmetry and phylogeny in mitochondrial DNA.

  Journal of theoretical biology 20051021

• Lymphocyte Hprt mutant frequency and sperm toxicity in C57BL/6 mice treated chronically with Azathioprine.

  Mutation research 20051015

• Hypermutation at A-T base pairs: the A nucleotide replacement spectrum is affected by adjacent nucleotides and there is no reverse complementarity of sequences flanking mutated A and T nucleotides.

  Journal of immunology (Baltimore, Md. : 1950) 20051015

• Short-term safety and pharmacodynamics of amdoxovir in HIV-infected patients.

  AIDS (London, England) 20051014

• DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone after intratracheal instillation in rats.

  International journal of cancer 20051010

• Pathogenesis of gout.

  Annals of internal medicine 20051004

• [Uric acid as a marker of pathophysiological mechanisms in patients with cardiovascular disease].

  Ugeskrift for laeger 20051003

• Nucleoside transporter expression and function in cultured mouse astrocytes.

  Glia 20051001

• l-Arginine attenuates cardiovascular impairment in DOCA-salt hypertensive rats.

  American journal of physiology. Heart and circulatory physiology 20051001

• Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons.

  Neurochemistry international 20051001

• Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.

  Clinical chemistry 20051001

• Comparison between reduced intensity and conventional myeloablative allogeneic stem-cell transplantation in patients with hematologic malignancies aged between 50 and 59 years.

  Bone marrow transplantation 20051001

• Adenosine receptor signaling in the brain immune system.

  Trends in pharmacological sciences 20051001

• Old and new insights into the mechanisms of action of two nucleoside analogs active in lymphoid malignancies: fludarabine and cladribine (review).

  International journal of oncology 20051001

• Empiric therapy of autoimmune hepatitis with mycophenolate mofetil: comparison with conventional treatment for refractory disease.

  Journal of clinical gastroenterology 20051001

• The influence of allopurinol on urinary purine loss after repeated sprint exercise in man.

  Metabolism: clinical and experimental 20051001

• Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine.

  Archives of biochemistry and biophysics 20051001

• The identification of 5'-fluoro-5-deoxyinosine as a shunt product in cell free extracts of Streptomyces cattleya.

  Bioorganic chemistry 20051001

• Nucleoside 5'-triphosphates: self-association, acid-base, and metal ion-binding properties in solution.

  Chemical Society reviews 20051001

• High activity and incomplete cross resistance of nucleoside analogues cladribine and fludarabine versus Ara-C on leukemic cells from patients with AML.

  Therapeutic drug monitoring 20051001

• Dependence of nucleotide physical properties on their placement in codons and determinative degree.

  Journal of Zhejiang University. Science. B 20051001

• Structure and energetics of clustered damage sites.

  Radiation research 20051001

• DNA-bound Bas1 recruits Pho2 to activate ADE genes in Saccharomyces cerevisiae.

  Eukaryotic cell 20051001

• Protein molecular function prediction by Bayesian phylogenomics.

  PLoS computational biology 20051001

• Successful treatment of refractory thrombocytopenia with mycophenolate mofetil in a patient with systemic lupus erythematosus.

  Journal of Korean medical science 20051001

• A3 adenosine receptors modulate hypoxia-inducible factor-1alpha expression in human A375 melanoma cells.

  Neoplasia (New York, N.Y.) 20051001

• A single-cell analysis of myogenic dedifferentiation induced by small molecules.

  Chemistry & biology 20051001

• Effects of long-term beer ingestion on plasma concentrations and urinary excretion of purine bases.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001

• Allopurinol or oxypurinol in heart failure therapy - a promising new development or end of story?

  Cardiovascular drugs and therapy 20051001

• Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability.

  Expert opinion on drug metabolism & toxicology 20051001

• Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates.

  The Journal of organic chemistry 20050930

• Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis.

  Journal of molecular biology 20050923

• Phenyl radicals react with dinucleoside phosphates by addition to purine bases and H-atom abstraction from a sugar moiety.

  Journal of the American Chemical Society 20050921

• 8-Azapurines as new inhibitors of cyclin-dependent kinases.

  Bioorganic & medicinal chemistry 20050915

• Endogenous DNA damage clusters in human skin, 3-D model, and cultured skin cells.

  Free radical biology & medicine 20050915

• Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050915

• Molecular recognition via triplex formation of mixed purine/pyrimidine DNA sequences using oligoTRIPs.

  Journal of the American Chemical Society 20050914

• Immediate up-regulation of the calcium-binding protein S100P and its involvement in the cytokinin-induced differentiation of human myeloid leukemia cells.

  Biochimica et biophysica acta 20050910

• Current treatment approaches for mantle-cell lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050910

• Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides.

  Journal of medicinal chemistry 20050908

• Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria.

  Biochimica et biophysica acta 20050905

• A novel method for the synthesis of imidazo[5,1-f][1,2,4]triazin-4(3H)-ones.

  The Journal of organic chemistry 20050902

• Glutamine inhibits cytokine-induced apoptosis in human colonic epithelial cells via the pyrimidine pathway.

  American journal of physiology. Gastrointestinal and liver physiology 20050901

• Infections associated with purine analogs and monoclonal antibodies.

  Blood reviews 20050901

• Advances in understanding adenosine as a plurisystem modulator in sepsis and the systemic inflammatory response syndrome (SIRS).

  Frontiers in bioscience : a journal and virtual library 20050901

• The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides.

  FEMS microbiology letters 20050901

• Specificity of recognition of mRNA 5' cap by human nuclear cap-binding complex.

  RNA (New York, N.Y.) 20050901

• Mechanical loading stimulates ecto-ATPase activity in human tendon cells.

  Journal of cellular biochemistry 20050901

• Advances in the treatment of chronic lymphocytic leukemia.

  Current oncology reports 20050901

• Inhibition of endothelial activation: a new way to treat cerebral malaria?

  PLoS medicine 20050901

• The genomics of disulfide bonding and protein stabilization in thermophiles.

  PLoS biology 20050901

• Regioselective syntheses of 7-nitro-7-deazapurine nucleosides and nucleotides for efficient PCR incorporation.

  Organic letters 20050901

• An unusual occurrence on attempted purine C-8 electrophilic fluorination of 5'-noraristeromycin.

  Organic letters 20050901

• Adenosine deaminase and 5'-nucleotidase activities in saliva from patients with oral and laryngeal cancer.

  Oral diseases 20050901

• Purine metabolites in gout and asymptomatic hyperuricemia: analysis by HPLC-electrospray tandem mass spectrometry.

  Clinical chemistry 20050901

• Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation.

  Acta physiologica Scandinavica 20050901

• Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.

  Acta crystallographica. Section D, Biological crystallography 20050901

• The systemic theory of living systems and relevance to CAM: the theory (Part III).

  Evidence-based complementary and alternative medicine : eCAM 20050901

• The pharmacological potential of mushrooms.

  Evidence-based complementary and alternative medicine : eCAM 20050901

• Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha.

  Chemical research in toxicology 20050901

• The structure of DNA dictates purine atom site selectivity in alkylation by primary diazonium ions.

  Chemical research in toxicology 20050901

• Regional differences in extracellular purine degradation in the prostatic and epididymal portions of the rat vas deferens.

  Clinical and experimental pharmacology & physiology 20050901

• Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications.

  Current cancer drug targets 20050901

• REC, Drosophila MCM8, drives formation of meiotic crossovers.

  PLoS genetics 20050901

• Pentostatin/cyclophosphamide with or without rituximab: an effective regimen for patients with Waldenstrom's macroglobulinemia/lymphoplasmacytic lymphoma.

  Clinical lymphoma & myeloma 20050901

• Signaling of the Human P2Y(1) Receptor Measured by a Yeast Growth Assay with Comparisons to Assays of Phospholipase C and Calcium Mobilization in 1321N1 Human Astrocytoma Cells.

  Purinergic signalling 20050901

• P2X(7) receptor: Death or life?

  Purinergic signalling 20050901

• Dynamic purine signaling and metabolism during neutrophil-endothelial interactions.

  Purinergic signalling 20050901

• Cloning and characterization of the ecto-nucleotidase NTPDase3 from rat brain: Predicted secondary structure and relation to other members of the E-NTPDase family and actin.

  Purinergic signalling 20050901

• Tri-nucleotide receptors play a critical role in epithelial cell wound repair.

  Purinergic signalling 20050901

• Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography.

  Journal of the American Chemical Society 20050831

• Procatalytic ligand strain. Ionization and perturbation of 8-nitroxanthine at the urate oxidase active site.

  Biochemistry 20050830

• Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.

  The Journal of biological chemistry 20050826

• Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites.

  Journal of medicinal chemistry 20050825

• Three-state conical intersections in nucleic acid bases.

  The journal of physical chemistry. A 20050825

• Mutational analysis of a nucleosidase involved in quorum-sensing autoinducer-2 biosynthesis.

  Biochemistry 20050823

• The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides.

  Organic & biomolecular chemistry 20050821

• Total synthesis of N-malayamycin A and related bicyclic purine and pyrimidine nucleosides.

  The Journal of organic chemistry 20050819

• Conformational change in the catalytic site of the ribonuclease YoeB toxin by YefM antitoxin.

  Molecular cell 20050819

• Substrate discrimination by the human GTP fucose pyrophosphorylase.

  Biochemistry 20050816

• Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors.

  Cancer research 20050815

• Plasma and cerebrospinal fluid pharmacokinetics of clofarabine in nonhuman primates.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050815

• The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.

  Journal of molecular biology 20050805

• Stabilization of purine motif DNA triplex by a tetrapeptide from the binding domain of HMGBI protein.

  Biochimie 20050801

• Methylated purines in urinary stones.

  Clinical chemistry 20050801

• Nucleotide metabolism and its control in lactic acid bacteria.

  FEMS microbiology reviews 20050801

• A solid-phase approach to novel purine and nucleoside analogs.

  Bioorganic & medicinal chemistry 20050801

• Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ.

  Bioorganic & medicinal chemistry 20050801

• Interaction centres of pyrimidine nucleotides: cytidine-5'-diphosphate (CDP) and cytidine-5'-triphosphate (CTP) in their reactions with tetramines and Cu(II) ions.

  Journal of inorganic biochemistry 20050801

• Therapy-related acute myeloid leukemia after single-agent treatment with fludarabine for chronic lymphocytic leukemia.

  American journal of hematology 20050801

• Emerging drugs for adult acute lymphoblastic leukaemia.

  Expert opinion on emerging drugs 20050801

• A global survey of gene regulation during cold acclimation in Arabidopsis thaliana.

  PLoS genetics 20050801

• 6-(N-benzoylamino)purine as a novel and potent inhibitor of xanthine oxidase: inhibition mechanism and molecular modeling studies.

  Journal of enzyme inhibition and medicinal chemistry 20050801

• Residue specific ribose and nucleobase dynamics of the cUUCGg RNA tetraloop motif by MNMR 13C relaxation.

  Journal of biomolecular NMR 20050801

• Selective DNAzyme-mediated cleavage of AChR mutant transcripts by targeting the mutation site or through mismatches in the binding arm.

  Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 20050801

• Inosine improves islet xenograft survival in immunocompetent diabetic mice.

  European journal of medical research 20050729

• Increased expression of mRNA specific for thymidine kinase, deoxycytidine kinase or thymidine phosphorylase in human papillary thyroid carcinoma.

  Cancer letters 20050728

• Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors.

  Journal of medicinal chemistry 20050728

• Effects of hydrogen bonding on the acidity of adenine, guanine, and their 8-oxo derivatives.

  The journal of physical chemistry. A 20050721

• Immunosuppression and infectious complications in patients with stage IV indolent lymphoma treated with a fludarabine, mitoxantrone, and dexamethasone regimen.

  Cancer 20050715

• The nucleobase-ascorbate transporter (NAT) signature motif in UapA defines the function of the purine translocation pathway.

  Journal of molecular biology 20050715

• Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.

  Journal of medicinal chemistry 20050714

• The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.

  The Journal of biological chemistry 20050708

• Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA.

  The Journal of biological chemistry 20050708

• Stereoselective synthesis of beta-anomeric 4'-thiaspirocyclic ribonucleosides carrying the full complement of RNA-level hydroxyl substitution.

  The Journal of organic chemistry 20050708

• Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern University experience.

  Blood 20050701

• Structural elements in IGP synthase exclude water to optimize ammonia transfer.

  Biophysical journal 20050701

• In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050701

• Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy.

  Bioorganic & medicinal chemistry 20050701

• A role for adenosine deaminase in Drosophila larval development.

  PLoS biology 20050701

• AICAR suppresses IL-2 expression through inhibition of GSK-3 phosphorylation and NF-AT activation in Jurkat T cells.

  Biochemical and biophysical research communications 20050701

• DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine.

  Mutation research 20050701

• Contribution of the Saccharomyces cerevisiae transcriptional regulator Leu3p to physiology and gene expression in nitrogen- and carbon-limited chemostat cultures.

  FEMS yeast research 20050701

• Birth of a metabolic gene cluster in yeast by adaptive gene relocation.

  Nature genetics 20050701

• Structure of human PNP complexed with ligands.

  Acta crystallographica. Section D, Biological crystallography 20050701

• [MTH1, an oxidized purine nucleoside triphosphatase suppresses mitochondrial dysfunction and cell death caused by oxidative stress].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20050701

• Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells.

  The FEBS journal 20050701

• Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2'-deoxyguanosine.

  Chemical research in toxicology 20050701

• Effects of long-term treatment with mizoribine in patients with proliferative lupus nephritis.

  Clinical nephrology 20050701

• Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes.

  Archives of pharmacal research 20050701

• Virulence deficiency caused by a transposon insertion in the purH gene of Xanthomonas oryzae pv. oryzae.

  Canadian journal of microbiology 20050701

• Loss of ecto-5'nucleotidase from porcine endothelial cells after exposure to human blood: Implications for xenotransplantation.

  Biochimica et biophysica acta 20050630

• Modeling of purine derivatives transport across cell membranes based on their partition coefficient determination and quantum chemical calculations.

  Journal of medicinal chemistry 20050630

• Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9).

  The Journal of biological chemistry 20050624

• Role of an active site adenine in hairpin ribozyme catalysis.

  Journal of molecular biology 20050624

• Regulation and activity of cytosolic 5'-nucleotidase II. A bifunctional allosteric enzyme of the Haloacid Dehalogenase superfamily involved in cellular metabolism.

  FEBS letters 20050620

• Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.

  The Journal of biological chemistry 20050610

• Activation of alternative oxidase and uncoupling protein lowers hydrogen peroxide formation in amoeba Acanthamoeba castellanii mitochondria.

  FEBS letters 20050606

• Hepatoprotective effects of Hibiscus, Rosmarinus and Salvia on azathioprine-induced toxicity in rats.

  Life sciences 20050603

• Theoretical study of cisplatin binding to DNA: the importance of initial complex stabilization.

  The journal of physical chemistry. B 20050602

• Reduction of arsenate to arsenite by human erythrocyte lysate and rat liver cytosol - characterization of a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20050601

• Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.

  Neurochemistry international 20050601

• Regulation of purine biosynthesis by a eukaryotic-type kinase in Streptococcus agalactiae.

  Molecular microbiology 20050601

• Amphioxus allantoicase: molecular cloning, expression and enzymatic activity.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050601

• Transglycosylation: a mechanism for RNA modification (and editing?).

  Bioorganic chemistry 20050601

• Identification of the main oxidation products of 8-methoxy-2'-deoxyguanosine by singlet molecular oxygen.

  Free radical biology & medicine 20050601

• Radiation-induced hydroxyl addition to purine molecules: EPR and ENDOR study of hypoxanthine hydrochloride monohydrate single crystals.

  Radiation research 20050601

• Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis.

  Pharmacological reviews 20050601

• IMP dehydrogenase from the protozoan parasite Toxoplasma gondii.

  Antimicrobial agents and chemotherapy 20050601

• Renal urate handling: clinical relevance of recent advances.

  Current rheumatology reports 20050601

• Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children.

  Environmental health perspectives 20050601

• Adenine nucleotides in snail muscles as one of biomarkers of fluoride toxicity.

  Journal of environmental monitoring : JEM 20050601

• Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines.

  Journal of neurochemistry 20050601

• Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).

  Clinica chimica acta; international journal of clinical chemistry 20050601

• The plant Mo-hydroxylases aldehyde oxidase and xanthine dehydrogenase have distinct reactive oxygen species signatures and are induced by drought and abscisic acid.

  The Plant journal : for cell and molecular biology 20050601

• Outcomes of patients with acute leukaemia who relapsed after reduced-intensity stem cell transplantation from HLA-identical or one antigen-mismatched related donors.

  British journal of haematology 20050601

• Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selection.

  The FEBS journal 20050601

• TRAP220 is modulated by the antineoplastic agent 6-Mercaptopurine, and mediates the activation of the NR4A subgroup of nuclear receptors.

  Journal of molecular endocrinology 20050601

• Synthesis, characterization, and 32p-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthrone.

  Chemical research in toxicology 20050601

• [Comparative proteomics research on removing of large invasive plasmid pINV of Shigella flexneri 2a strain 2457T].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20050601

• Urinary excretion of purine derivatives in Bos indicus x Bos taurus crossbred cattle.

  The British journal of nutrition 20050601

• Screening of catalytically active microorganisms for the synthesis of 6-modified purine nucleosides.

  Biotechnology letters 20050601

• [Study of crystalluria in diabetic patients].

  Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20050601

• Downregulation of glial scarring after brain injury: the effect of purine nucleoside analogue ribavirin.

  Annals of the New York Academy of Sciences 20050601

• By the way, doctor. I have gout. I've read that foods high in purine can aggravate the condition. What is purine, and how can I reduce it in my diet.

  Harvard women's health watch 20050601

• [Hyperuricemia and disorders in content of amino acids-purine precursors in patients with autoimmune diseases and gout].

  Likars'ka sprava 20050601

• General acid catalysis by the hepatitis delta virus ribozyme.

  Nature chemical biology 20050601

• Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP.

  Purinergic signalling 20050601

• Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade.

  Purinergic signalling 20050601

• Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP.

  Purinergic signalling 20050601

• 2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors.

  Purinergic signalling 20050601

• Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

  Purinergic signalling 20050601

• Simultaneous determination of 16 purine derivatives in urinary calculi by gradient reversed-phase high-performance liquid chromatography with UV detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525

• Unusual usage of wobble modifications in mitochondrial tRNAs of the nematode Ascaris suum.

  FEBS letters 20050523

• Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520

• Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

  Bioorganic & medicinal chemistry 20050516

• Synthesis and biological evaluation of alpha- and gamma-carboxamide derivatives of 10-CF3CO-DDACTHF.

  Bioorganic & medicinal chemistry 20050516

• 6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.

  Biochemical pharmacology 20050515

• Single DNA molecules as probes of chromatographic surfaces.

  Analytical chemistry 20050515

• Microelectrode biosensor for real-time measurement of ATP in biological tissue.

  Analytical chemistry 20050515

• Comprehensive assignment of mass spectral signatures from individual Bacillus atrophaeus spores in matrix-free laser desorption/ionization bioaerosol mass spectrometry.

  Analytical chemistry 20050515

• Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.

  The Journal of biological chemistry 20050506

• Adenosine kinase inhibitors. 4. 6,8-Disubstituted purine nucleoside derivatives. Synthesis, conformation, and enzyme inhibition.

  Journal of medicinal chemistry 20050505

• Deactivation of triplet-excited riboflavin by purine derivatives: important role of uric acid in light-induced oxidation of milk sensitized by riboflavin.

  Journal of agricultural and food chemistry 20050504

• Visible light (>395 nm) causes micronuclei formation in mammalian cells without generation of cyclobutane pyrimidine dimers.

  Mutation research 20050502

• Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED.

  Bioorganic & medicinal chemistry letters 20050502

• Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy.

  The journal of gene medicine 20050501

• Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050501

• Capillary zone electrophoretic studies of interactions of some quaternary isoquinoline alkaloids with DNA constituents and DNA.

  Electrophoresis 20050501

• In vitro cytotoxic effect of proteasome inhibitor bortezomib in combination with purine nucleoside analogues on chronic lymphocytic leukaemia cells.

  European journal of haematology 20050501

• Immunosuppressive efficacy of mycophenolate mofetil when compared with azathioprine and mizoribine against peripheral lymphocytes from renal transplant recipients.

  Transplant international : official journal of the European Society for Organ Transplantation 20050501

• Three Prochlorococcus cyanophage genomes: signature features and ecological interpretations.

  PLoS biology 20050501

• Systems rebalancing of metabolism in response to sulfur deprivation, as revealed by metabolome analysis of Arabidopsis plants.

  Plant physiology 20050501

• Assessment of the genotoxic potential of nitric oxide-induced guanine lesions by in vitro reactions with Escherichia coli DNA polymerase I.

  Mutagenesis 20050501

• Stopped-flow studies of guanine binding by calf spleen purine nucleoside phosphorylase.

  Biophysical chemistry 20050501

• Functional characterization and expression analysis of a gene, OsENT2, encoding an equilibrative nucleoside transporter in rice suggest a function in cytokinin transport.

  Plant physiology 20050501

• Lesch-Nyhan disease in a female with a clinically normal monozygotic twin.

  Molecular genetics and metabolism 20050501

• Prolymphocytic leukemia.

  Current treatment options in oncology 20050501

• The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050501

• Purine nucleosides stimulate Na/K ATPase, and prolong survival in hemorrhagic shock.

  The Journal of trauma 20050501

• [Molecular studies of vardenafil].

  Zhonghua nan ke xue = National journal of andrology 20050501

• [Mizoribine].

  Nihon rinsho. Japanese journal of clinical medicine 20050501

• Clofarabine.

  Nature reviews. Drug discovery 20050501

• Azathioprine induced nodular regenerative hyperplasia in IBD patients.

  Gastroenterologie clinique et biologique 20050501

• Anicemycin, a new inhibitor of anchorage-independent growth of tumor cells from Streptomyces sp. TP-A0648.

  The Journal of antibiotics 20050501

• Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050501

• Genetically selected cyclic-peptide inhibitors of AICAR transformylase homodimerization.

  Angewandte Chemie (International ed. in English) 20050429

• The mechanism of selective purine C-nitration revealed: NMR studies demonstrate formation and radical rearrangement of an N7-nitramine intermediate.

  Journal of the American Chemical Society 20050427

• Investigation of systemic folate status, impact of alcohol intake and levels of DNA damage in mononuclear cells of breast cancer patients.

  British journal of cancer 20050425

• Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.

  Journal of molecular biology 20050422

• Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.

  Journal of medicinal chemistry 20050421

• Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.

  The Journal of biological chemistry 20050415

• 31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions.

  The Journal of biological chemistry 20050415

• Involvement of uracil nucleotides in protection of cardiomyocytes from hypoxic stress.

  Biochemical pharmacology 20050415

• Calcium activates erythrocyte AMP deaminase [isoform E (AMPD3)] through a protein-protein interaction between calmodulin and the N-terminal domain of the AMPD3 polypeptide.

  Biochemistry 20050412

• Evidence for the involvement of cytosolic 5'-nucleotidase (cN-II) in the synthesis of guanine nucleotides from xanthosine.

  The Journal of biological chemistry 20050408

• Synthesis, biological activity, and SAR of antimycobacterial 9-aryl-, 9-arylsulfonyl-, and 9-benzyl-6-(2-furyl)purines.

  Journal of medicinal chemistry 20050407

• Residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites.

  Molecular pharmacology 20050401

• Interactions of carboxypeptidase G2 with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications.

  Cancer chemotherapy and pharmacology 20050401

• Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency.

  International journal of oncology 20050401

• Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives.

  Bioorganic & medicinal chemistry 20050401

• Promising treatment of autoimmune hepatitis with 6-thioguanine after adverse events on azathioprine.

  European journal of gastroenterology & hepatology 20050401

• Stability of 3' double nucleotide overhangs that model the 3' ends of siRNA.

  RNA (New York, N.Y.) 20050401

• Molecular physiology of urate transport.

  Physiology (Bethesda, Md.) 20050401

• Phenotypic characterization of Rice Cluster III archaea without prior isolation by applying quantitative polymerase chain reaction to an enrichment culture.

  Environmental microbiology 20050401

• Pemetrexed (Alimta) in small cell lung cancer.

  Seminars in oncology 20050401

• The evolving role of pemetrexed (Alimta) in lung cancer.

  Seminars in oncology 20050401

• Three emerging new drugs for NSCLC: pemetrexed, bortezomib, and cetuximab.

  The oncologist 20050401

• 8-Amino-adenosine induces loss of phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2, and Akt kinase: role in induction of apoptosis in multiple myeloma.

  Molecular cancer therapeutics 20050401

• 6-substituted purines as inhibitors of 15-lipoxygenase; a structure-activity study.

  Archiv der Pharmazie 20050401

• Activity of purine catabolism enzymes during the reproductive cycle of male and female brown trout (Salmo trutta).

  Annals of the New York Academy of Sciences 20050401

• Mutations in PurBox1 of the Bacillus subtilis pur operon control site affect adenine-regulated expression in vivo.

  Science in China. Series C, Life sciences 20050401

• An investigation of prebiotic purine synthesis from the hydrolysis of HCN polymers.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20050401

• Effects of 6-mercaptopurine treatment on sperm production and reproductive performance: a study in male mice.

  Scandinavian journal of gastroenterology 20050401

• A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis.

  The Journal of biological chemistry 20050325

• Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase.

  The Journal of biological chemistry 20050325

• Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on-line sample preparation.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325

• Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate.

  Journal of molecular biology 20050325

• Paradoxical CD4+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine.

  AIDS (London, England) 20050324

• Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies.

  Biochemistry 20050322

• Synthesis and antimycobacterial activity of agelasine E and analogs.

  Organic & biomolecular chemistry 20050321

• Fluoro, alkylsulfanyl, and alkylsulfonyl leaving groups in suzuki cross-coupling reactions of purine 2'-deoxynucleosides and nucleosides.

  Organic letters 20050317

• Binding of six nucleotide cofactors to the hexameric helicase RepA protein of plasmid RSF1010. 2. Base specificity, nucleotide structure, magnesium, and salt effect on the cooperative binding of the cofactors.

  Biochemistry 20050315

• Casein kinase 2 regulates both apoptosis and the cell cycle following DNA damage induced by 6-thioguanine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050315

• Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.

  The Journal of biological chemistry 20050311

• Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.

  The Journal of biological chemistry 20050304

• Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria.

  The Journal of biological chemistry 20050304

• Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase.

  Life sciences 20050304

• 'Molecular chameleons'. Design and synthesis of a second series of flexible nucleosides.

  The Journal of organic chemistry 20050304

• Home-based exercise training modulates pro-oxidant substrates in patients with chronic heart failure.

  European journal of heart failure 20050302

• In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling.

  American journal of physiology. Lung cellular and molecular physiology 20050301

• Identification and characterization of purine nucleoside transporters from Crithidia fasciculata.

  Molecular and biochemical parasitology 20050301

• Limitation of podocyte proliferation improves renal function in experimental crescentic glomerulonephritis.

  Kidney international 20050301

• Solution structure of an RNA internal loop with three consecutive sheared GA pairs.

  Biochemistry 20050301

• Local conformational changes induced in B-DNA by ethidium intercalation.

  Biochemistry 20050301

• Topolins and hydroxylated thidiazuron derivatives are substrates of cytokinin O-glucosyltransferase with position specificity related to receptor recognition.

  Plant physiology 20050301

• How many functional transport pathways does Plasmodium falciparum induce in the membrane of its host erythrocyte?

  Trends in parasitology 20050301

• Use of odd and branched-chain fatty acids in rumen contents and milk as a potential microbial marker.

  Journal of dairy science 20050301

• Urinary trivalent methylated arsenic species in a population chronically exposed to inorganic arsenic.

  Environmental health perspectives 20050301

• Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies.

  Haematologica 20050301

• Metal complexes with aromatic N-containing ligands as potential agents in cancer treatment.

  Current medicinal chemistry. Anti-cancer agents 20050301

• [Progress in therapeutic strategy for malignant lymphoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050301

• Identification of the first pyrimidine nucleobase transporter in Leishmania: similarities with the Trypanosoma brucei U1 transporter and antileishmanial activity of uracil analogues.

  Parasitology 20050301

• Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.

  Human gene therapy 20050301

• [News in therapeutic management of chronic lymphoid leukemia].

  Bulletin du cancer 20050301

• Purine level regulation during energy depletion associated with graded excitatory stimulation in brain.

  Neurological research 20050301

• Astrocytes and neurons: different roles in regulating adenosine levels.

  Neurological research 20050301

• Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.

  Pharmacogenetics and genomics 20050301

• The origin and evolution of operons: the piecewise building of the proteobacterial histidine operon.

  Journal of molecular evolution 20050301

• Effects of Rebixiao granules on blood uric acid in patients with repeatedly attacking acute gouty arthritis.

  Chinese journal of integrative medicine 20050301

• Heart failure, oxidative stress and allopurinol.

  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20050301

• Advances in the diagnosis and treatment of chronic lymphocytic leukemia.

  Hematological oncology 20050301

• New catalytic mechanism for human purine nucleoside phosphorylase.

  Biochemical and biophysical research communications 20050218

• Exploring human adenosine A3 receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety.

  Bioorganic & medicinal chemistry 20050215

• Aqueous extract of Ilex paraguariensis decreases nucleotide hydrolysis in rat blood serum.

  Journal of ethnopharmacology 20050210

• Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors.

  Journal of medicinal chemistry 20050210

• Solvatochromism of a novel betaine dye derived from purine.

  The journal of physical chemistry. A 20050210

• Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.

  American journal of physiology. Renal physiology 20050201

• The place of cladribine in the treatment of chronic lymphocytic leukemia: a 10-year experience in Poland.

  Annals of hematology 20050201

• Dynamics and stability of GCAA tetraloops with 2-aminopurine and purine substitutions.

  Journal of biomolecular structure & dynamics 20050201

• Purine- and pyrimidine-induced responses and P2Y receptor characterization in the hamster proximal urethra.

  British journal of pharmacology 20050201

• The snRNP 15.5K protein folds its cognate K-turn RNA: a combined theoretical and biochemical study.

  RNA (New York, N.Y.) 20050201

• Allosteric mechanisms in ACT domain containing enzymes involved in amino acid metabolism.

  Amino acids 20050201

• Stereoselective synthesis of 9-beta-d-arabianofuranosyl guanine and 2-amino-9-(beta-d-arabianofuranosyl)purine.

  Bioorganic & medicinal chemistry letters 20050201

• Synthesis of 9-(2-beta-C-methyl-beta-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication.

  Bioorganic & medicinal chemistry letters 20050201

• Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor.

  Nature medicine 20050201

• ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis.

  Journal of clinical pathology 20050201

• Induction of CCAAT/enhancer binding protein-delta by cytokinins, but not by retinoic acid, during granulocytic differentiation of human myeloid leukaemia cells.

  British journal of haematology 20050201

• Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance.

  Experimental parasitology 20050201

• Beneficial antipsychotic effects of allopurinol as add-on therapy for schizophrenia: a double blind, randomized and placebo controlled trial.

  Progress in neuro-psychopharmacology & biological psychiatry 20050201

• 3-Bromo-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine: a nucleoside which strongly enhances DNA duplex stability.

  Acta crystallographica. Section C, Crystal structure communications 20050201

• Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050201

• Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201

• Hairy cell leukemia: survival and relapse. Long-term follow-up of purine analog-based therapy and approach for relapsed disease.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201

• First self.

  Emerging infectious diseases 20050201

• [Researches on the establishment of chronic nephropathy models and the effect of TCM on these models].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050201

• Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer.

  British journal of cancer 20050131

• Detection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clamping and hybridisation probes.

  British journal of cancer 20050131

• Synthesis and antiviral evaluation of cis-substituted cyclohexenyl and cyclohexanyl nucleosides.

  Journal of medicinal chemistry 20050127

• Hemodynamic and respiratory responses to microinjection of ATP into the intermediate and caudal NTS of awake rats.

  Brain research 20050125

• Hydrogen bonding and covalent effects in binding of cisplatin to purine bases: ab initio and atoms in molecules studies.

  Inorganic chemistry 20050124

• Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter.

  The Journal of biological chemistry 20050121

• Relation of enzyme activity to local/global stability of murine adenosine deaminase: 19F NMR studies.

  Journal of molecular biology 20050121

• Transient expression and flux changes during a shift from high to low riboflavin production in continuous cultures of Bacillus subtilis.

  Biotechnology and bioengineering 20050120

• Synthesis and EPR studies of 2-N-tert-butylaminoxylpurine derivatives.

  Organic letters 20050120

• Active site plasticity of endonuclease V from Salmonella typhimurium.

  Biochemistry 20050118

• Mechanism of action of Escherichia coli phosphoribosylaminoimidazolesuccinocarboxamide synthetase.

  Biochemistry 20050118

• Clinical anticancer drug development: targeting the cyclin-dependent kinases.

  British journal of cancer 20050117

• The fluorescence enhancement effect of Tb-Gd-adenosine triphosphate-phen system and its analytical application.

  Talanta 20050115

• Crystal structure of human PNP complexed with hypoxanthine and sulfate ion.

  Biochemical and biophysical research communications 20050114

• Nucleotides and pronucleotides of 2,2-bis(hydroxymethyl)methylenecyclopropane analogues of purine nucleosides: synthesis and antiviral activity.

  Journal of medicinal chemistry 20050113

• How flexible are fleximer nucleobases? A computational study.

  The journal of physical chemistry. A 20050113

• The N6-methyl group of adenine further increases the BI stability of DNA compared to C5-methyl groups.

  The journal of physical chemistry. B 20050113

• Nanocrystal-based bioelectronic coding of single nucleotide polymorphisms.

  Journal of the American Chemical Society 20050112

• Synthesis of oligonucleotides containing Fapy.dG (N(6)-(2-deoxy-alpha,beta-D-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine) using a 5'-dimethoxytrityl dinucleotide phosphoramidite.

  The Journal of organic chemistry 20050107

• 'Molecular chameleons'. Design and synthesis of C-4-substituted imidazole fleximers.

  Organic letters 20050106

• The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation.

  Bioorganic & medicinal chemistry 20050103

• shRNA-mediated RNA interference as a tool for genetic synthetic lethality screening in mouse embryo fibroblasts.

  FEBS letters 20050103

• Base-modified oligonucleotides with increased duplex stability: pyrazolo[3,4-d] pyrimidines replacing purines.

  Methods in molecular biology (Clifton, N.J.) 20050101

• HeLa cell nucleus, a source of thymidine for Trichomonas vaginalis growing in vitro.

  The international journal of biochemistry & cell biology 20050101

• Molecular analysis of mutations in the human HPRT gene.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Splenic marginal zone lymphoma.

  Blood reviews 20050101

• Enzymatic transition states: thermodynamics, dynamics and analogue design.

  Archives of biochemistry and biophysics 20050101

• Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.

  Neuroscience research 20050101

• Purine metabolism and hyperuricemic states. 'The point of view of the rheumatologist'.

  Contributions to nephrology 20050101

• Hyperuricemia and bone marrow transplantation.

  Contributions to nephrology 20050101

• Rasburicase therapy in acute hyperuricemia and renal dysfunction.

  Contributions to nephrology 20050101

• 8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1.

  Radiation research 20050101

• Growth inhibition of Listeria monocytogenes by a nonbacteriocinogenic Carnobacterium piscicola.

  Journal of applied microbiology 20050101

• Addicted to death: invasive cancer and the immune response to unscheduled cell death.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20050101

• Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101

• Proapoptotic activity of alemtuzumab alone and in combination with rituximab or purine nucleoside analogues in chronic lymphocytic leukemia cells.

  Leukemia & lymphoma 20050101

• The structure of a rigorously conserved RNA element within the SARS virus genome.

  PLoS biology 20050101

• Differences in codon bias cannot explain differences in translational power among microbes.

  BMC bioinformatics 20050101

• Microarray-based resequencing of multiple Bacillus anthracis isolates.

  Genome biology 20050101

• Computational prediction of human metabolic pathways from the complete human genome.

  Genome biology 20050101

• Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.

  Genome biology 20050101

• Generation of predictive pharmacophore model for SARS-coronavirus main proteinase.

  European journal of medicinal chemistry 20050101

• Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy.

  BMC cancer 20050101

• Selection and characterization of a promoter for expression of single-copy recombinant genes in Gram-positive bacteria.

  BMC biotechnology 20050101

• Metabolism and pharmacokinetics of the cyclin-dependent kinase inhibitor R-roscovitine in the mouse.

  Molecular cancer therapeutics 20050101

• Hereditary hyperuricemia and renal disease.

  Seminars in nephrology 20050101

• Molecular models of NS3 protease variants of the Hepatitis C virus.

  BMC structural biology 20050101

• Riboswitch structures: purine ligands replace tertiary contacts.

  Chemistry & biology 20050101

• Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation.

  Advances in immunology 20050101

• Severe and steroid-resistant Crohn's disease.

  Digestion 20050101

• Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome.

  Clinical neuropharmacology 20050101

• Synthesis and biological evaluation of 2- and 7-substituted 9-deazaadenosine analogues.

  Nucleosides, nucleotides & nucleic acids 20050101

• Molecular strategies to inhibit HIV-1 replication.

  Retrovirology 20050101

• Using purine skews to predict genes in AT-rich poxviruses.

  BMC genomics 20050101

• Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3).

  The pharmacogenomics journal 20050101

• A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.

  Arthritis research & therapy 20050101

• Application of population pharmacokinetics to cladribine.

  BMC pharmacology 20050101

• Electrospray ionization mass spectrometric study of purine base-cisplatin complexes.

  Rapid communications in mass spectrometry : RCM 20050101

• Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.

  Malaria journal 20050101

• The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum.

  Genome biology 20050101

• Modulation of cytokine release by purine receptors in patients with rheumatoid arthritis.

  Clinical and experimental rheumatology 20050101

• Accelerated probabilistic inference of RNA structure evolution.

  BMC bioinformatics 20050101

• Managing malignancy-associated hyperuricemia with rasburicase.

  The journal of supportive oncology 20050101

• In silico studies toward the discovery of new anti-HIV nucleoside compounds through the use of TOPS-MODE and 2D/3D connectivity indices. 2. Purine derivatives.

  Journal of chemical information and modeling 20050101

• Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens.

  BMC infectious diseases 20050101

• Fludarabine phosphate may be useful in the treatment of graft-versus-host disease.

  Medical hypotheses 20050101

• Evolutionary distance estimation and fidelity of pair wise sequence alignment.

  BMC bioinformatics 20050101

• [Disfunction of thyroid gland at experimental hyperuricemia].

  Biomeditsinskaia khimiia 20050101

• Investigating hookworm genomes by comparative analysis of two Ancylostoma species.

  BMC genomics 20050101

• Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence.

  BMC cell biology 20050101

• Rational polynomial representation of ribonucleotide reductase activity.

  BMC biochemistry 20050101

• Preparation of a fully substituted purine library.

  Journal of combinatorial chemistry 20050101

• [Applicability of fozinopril for correction of basic manifestations of metabolic syndrome in women with arterial hypertension].

  Terapevticheskii arkhiv 20050101

• Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axes.

  BMC genomics 20050101

• Confocal fluorescence imaging of photosensitized DNA denaturation in cell nuclei.

  Photochemistry and photobiology 20050101

• P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia.

  International journal of immunopathology and pharmacology 20050101

• Neutrophil chemotaxis: autotaxin induced attenuation of purine/pyrimidine signaling precede the overexpression of Integrin(s).

  Medical hypotheses 20050101

• HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae.

  BMC microbiology 20050101

• Adenovirus-mediated interleukin-12 gene transfer combined with cytosine deaminase followed by 5-fluorocytosine treatment exerts potent antitumor activity in Renca tumor-bearing mice.

  BMC cancer 20050101

• Synthesis and biodistribution of [11C]adenosine 5'-monophosphate ([11C]AMP).

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20050101

• Genetic islands of Streptococcus agalactiae strains NEM316 and 2603VR and their presence in other Group B streptococcal strains.

  BMC microbiology 20050101

• Metabolic effects of novel N-1-sulfonylpyrimidine derivatives on human colon carcinoma cells.

  Farmaco (Societa chimica italiana : 1989) 20050101

• Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast.

  BMC genetics 20050101

• [Enzymes of purine nucleotide metabolism in assessment of the functional competence of the immune system].

  Biomeditsinskaia khimiia 20050101

• Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.

  BMC immunology 20050101

• Severe skin reaction related to mycophenolate mofetil for myasthenia gravis.

  Clinical neuropharmacology 20050101

• Modulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors.

  BMC immunology 20050101

• [Severity of a female gout course].

  Terapevticheskii arkhiv 20050101

• The genomics of probiotic intestinal microorganisms.

  Genome biology 20050101

• [Polymethylene derivatives of nucleic bases with omega-functional groups: IV. [7-(2-oxocyclohexyl)-7-oxoheptyl]purines].

  Bioorganicheskaia khimiia 20050101

• Parallel solution-phase synthesis of a 2,6,8,9-tetrasubstituted purine library via a sulfur intermediate.

  Journal of combinatorial chemistry 20050101

• The purine nucleotide content in human leukemia cell lines.

  Cellular & molecular biology letters 20050101

• Purine metabolism in pigs and humans and its implications for xenotransplantation.

  Nucleosides, nucleotides & nucleic acids 20050101

• A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools.

  BMC bioinformatics 20050101

• Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels.

  Thrombosis journal 20050101

• Folate system correlations in DNA microarray data.

  BMC cancer 20050101

• Evolution of selenium utilization traits.

  Genome biology 20050101

• Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria.

  Genome biology 20050101

• Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man.

  European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20050101

• Bystander effects in UV-induced genomic instability: antioxidants inhibit delayed mutagenesis induced by ultraviolet A and B radiation.

  Journal of carcinogenesis 20050101

• Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors.

  BMC genomics 20050101

• Inhibition of glycinamide ribonucleotide formyltransferase results in selective inhibition of macrophage cytokine secretion in vitro and in vivo efficacy in rat adjuvant arthritis.

  Clinical and experimental rheumatology 20050101

• Three subsets of sequence complexity and their relevance to biopolymeric information.

  Theoretical biology & medical modelling 20050101

• Cloning and functional characterization of two bacterial members of the NAT/NCS2 family in Escherichia coli.

  Molecular membrane biology 20050101

• Comparative substrate recognition by bacterial and fungal purine transporters of the NAT/NCS2 family.

  Molecular membrane biology 20050101

• Enhanced efficacy of gemcitabine in combination with anti-CD20 monoclonal antibody against CD20+ non-Hodgkin's lymphoma cell lines in vitro and in scid mice.

  BMC cancer 20050101

• A case report of Merkel cell carcinoma on chronic lymphocytic leukemia: differential diagnosis of coexisting lymphadenopathy and indications for early aggressive treatment.

  BMC cancer 20050101

• Clofarabine: in pediatric patients with acute lymphoblastic leukemia.

  Paediatric drugs 20050101

• Antitumor polycyclic acridines. Part 16. Triplex DNA as a target for DNA-binding polycyclic acridine derivatives.

  Oncology research 20050101

• [Nuclease biosynthesis and growth of Serratia marcescens in the presence of 2-(p-aminobenzenesulfonamide)-thiazole].

  Mikrobiologiia 20050101

• Organic acid toxicity, tolerance, and production in Escherichia coli biorefining applications.

  Microbial cell factories 20050101

• Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system.

  Reproductive biology and endocrinology : RB&E 20050101

• [Diagnostic aspects of familial juvenile hyperuriceamic nephropathy].

  Casopis lekaru ceskych 20050101

• Disorders of purine and pyrimidine metabolism.

  Molecular genetics and metabolism 20050101

• Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich.

  BMC genomics 20050101

• Digital drug discovery.

  Genome biology 20050101

• Separation of genomic DNA from plasmid DNA by selective renaturation with immobilized metal affinity capture.

  Biotechnology progress 20050101

• Evidence of recombination among early-vaccination era measles virus strains.

  BMC evolutionary biology 20050101

• The distribution of SNPs in human gene regulatory regions.

  BMC genomics 20050101

• Evolutionary relationship and application of a superfamily of cyclic amidohydrolase enzymes.

  Chemical record (New York, N.Y.) 20050101

• Regression of long standing anorexia nervosa following acute renal failure caused by gentamicin intoxication.

  Przeglad lekarski 20050101

• Evolutionary, structural and functional relationships revealed by comparative analysis of syntenic genes in Rhizobiales.

  BMC evolutionary biology 20050101

• Comparative genomics of Thermus thermophilus and Deinococcus radiodurans: divergent routes of adaptation to thermophily and radiation resistance.

  BMC evolutionary biology 20050101

• HPRT deficiency as the cause of ESRD in a 24-year-old patient: a very rare presentation of the disorder.

  Journal of nephrology 20050101

• Synthesis of complex nucleoside antibiotics.

  Nucleosides, nucleotides & nucleic acids 20050101

• Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, and its 9-(2-phosphonylmethoxyethyl) derivative.

  Nucleosides, nucleotides & nucleic acids 20050101

• Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and antitumor activity of 5-bromo-1-mesyluracil.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis of 2'-C-methyl-beta-D-ribofuranosylimidazo [4,5-d]-pyridazine derivatives (2-aza-3-deazapurine nucleoside analogues).

  Nucleosides, nucleotides & nucleic acids 20050101

• Ring-expanded analogues of natural oxetanocin: (+) and (-) hydroxymethyl isodideoxyadenosine.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis of racemic and enantiomeric 3-pyrrolidinyl derivatives of purine and pyrimidine nucleobases.

  Nucleosides, nucleotides & nucleic acids 20050101

• Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.

  Nucleosides, nucleotides & nucleic acids 20050101

• Cdk inhibitory nucleoside analogs prevent transcription from viral genomes.

  Nucleosides, nucleotides & nucleic acids 20050101

• 7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides.

  Nucleosides, nucleotides & nucleic acids 20050101

• 6-azapyrimidine and 7-deazapurine 2'-deoxy-2'-fluoroarabinonucleosides: synthesis, conformation and properties of oligonucleotides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and biological activity of 2'-deoxy-4'-thio-pyrazolo[3,4-d]pyrimidine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and anti-hepatitis C virus activity of nucleoside derivatives of N3, 5'-anhydro-4-(beta-D-ribofuranosyl)-8-aza-purin-2-ones.

  Nucleosides, nucleotides & nucleic acids 20050101

• Functionalization of pyrimidine and purine nucleosides at C4 and C6: C-nucleophilic substitution of their C4- and C6-(1,2,4-triazol-1-yl) derivatives.

  Nucleosides, nucleotides & nucleic acids 20050101

• Stereoselective synthesis of novel thioiso dideoxy nucleosides with exocyclic methylene as potential antiviral agents.

  Nucleosides, nucleotides & nucleic acids 20050101

• Chemistry and dynamics of interaction of nucleosides with pentafluoropyridine.

  Nucleosides, nucleotides & nucleic acids 20050101

• Propofol attenuates oxidant-induced acute lung injury in an isolated perfused rabbit-lung model.

  Journal of anesthesia 20050101

• Preclinical development of Alimta (Pemetrexed, LY231514), a multitargeted antifolate.

  Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20050101

• The contact-mediated response of peripheral-blood monocytes to preactivated T cells is suppressed by serum factors in rheumatoid arthritis.

  Arthritis research & therapy 20050101

• A computational investigation of kinetoplastid trans-splicing.

  Genome biology 20050101

• Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers.

  BMC biochemistry 20050101

• Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial (ISRCTN68505294).

  Nutrition journal 20050101

• Salvage therapy for CLL and the role of stem cell transplantation.

  Hematology. American Society of Hematology. Education Program 20050101

• Transition states and inhibitors of the purine nucleoside phosphorylase family.

  Current topics in medicinal chemistry 20050101

• PNP anticancer gene therapy.

  Current topics in medicinal chemistry 20050101

• Purine derivatives as ligands for A3 adenosine receptors.

  Current topics in medicinal chemistry 20050101

• Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5.

  BMC biochemistry 20050101

• Biphasic effect of extracellular ATP on human and rat airways is due to multiple P2 purinoceptor activation.

  Respiratory research 20050101

• A phase II study of fixed dose rate gemcitabine in patients with relapsed müllerian tumors.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101

• Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and controversies.

  Drugs & aging 20050101

• Overview of hyperuricaemia and gout.

  Current pharmaceutical design 20050101

• Dietary factors and hyperuricaemia.

  Current pharmaceutical design 20050101

• Uric acid and oxidative stress.

  Current pharmaceutical design 20050101

• Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

• Inhibition of defective adenylosuccinate lyase by HNE: a neurological disease that may be affected by oxidative stress.

  BioFactors (Oxford, England) 20050101

• Immunotherapeutic approaches in ocular inflammatory diseases.

  Archivum immunologiae et therapiae experimentalis 20050101

• [Immunosuppressive drugs and renal transplantation].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101

• Molecular processes during fat cell development revealed by gene expression profiling and functional annotation.

  Genome biology 20050101

• Synthesis and anti-HIV activity of beta-D-3'-azido-2',3'-unsaturated nucleosides and beta-D-3'-azido-3'-deoxyribofuranosylnucleosides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and pharmacokinetic and pharmacodynamic evaluation of the forodesine HCl analog BCX-3040.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and biological activity of 4'-thio-L-xylofuranosyl purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Pyrimidine and purine analogues, effects on cell cycle regulation and the role of cell cycle inhibitors to enhance their cytotoxicity.

  Nucleosides, nucleotides & nucleic acids 20050101

• Integrative analysis of genome-wide experiments in the context of a large high-throughput data compendium.

  Molecular systems biology 20050101

• Searching genomes for noncoding RNA using FastR.

  IEEE/ACM transactions on computational biology and bioinformatics 20050101

• Novel modified purine bases and nucleosides: new methodologies of synthesis and biological activity.

  Nucleic acids symposium series (2004) 20050101

• Biophysical and biochemical properties of oxanine-containing oligodeoxynucleotide.

  Nucleic acids symposium series (2004) 20050101

• Synthesis of purin-2-yl carboxylate from O6-methylguanosine.

  Nucleic acids symposium series (2004) 20050101

• Activity of nucleotide excision repair enzymes for oxanine cross-link lesions.

  Nucleic acids symposium series (2004) 20050101

• Mycophenolate Mofetil (MMF) Efficacy in Glomerulonephritis (GN), a Retrospective Analysis.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20050101

• Genetic barriers to resistance and impact on clinical response.

  Journal of the International AIDS Society 20050101

• Exotic diseases of dogs and cats at risk of importation to Ireland.

  Irish veterinary journal 20050101

• Synthesis and antitumor activity of methyltriazene prodrugs simultaneously releasing DNA-methylating agents and the antiresistance drug O(6)-benzylguanine.

  Journal of medicinal chemistry 20041230

• Cocyclotrimerization of 6-alkynylpurines with alpha,omega-diynes as a novel approach to biologically active 6-arylpurines.

  The Journal of organic chemistry 20041224

• Active site contacts in the purine nucleoside phosphorylase--hypoxanthine complex by NMR and ab initio calculations.

  Biochemistry 20041221

• Synthesis of a biotin-conjugate of phosmidosine O-ethyl ester as a G1 arrest antitumor drug.

  Bioorganic & medicinal chemistry 20041215

• Monitoring HSVtk suicide gene therapy: the role of [(18)F]FHPG membrane transport.

  British journal of cancer 20041213

• Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment.

  British journal of cancer 20041213

• Production of the carbonate radical anion during xanthine oxidase turnover in the presence of bicarbonate.

  The Journal of biological chemistry 20041210

• Human deoxycytidine kinase as a deoxyribonucleoside phosphorylase.

  Journal of molecular biology 20041210

• Isolation of fast purine nucleotide synthase ribozymes.

  Journal of the American Chemical Society 20041208

• Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study.

  Journal of the American Chemical Society 20041208

• Hyperbaric and normobaric reoxygenation of hypoxic rat brain slices--impact on purine nucleotides and cell viability.

  Neurochemistry international 20041201

• Adenosine stimulation of proliferation of breast carcinoma cell lines: evaluation of the [3H]thymidine assay system and modulatory effects of the cellular microenvironment in vitro.

  Journal of cellular physiology 20041201

• Glutathione-dependent reduction of arsenate in human erythrocytes--a process independent of purine nucleoside phosphorylase.

  Toxicological sciences : an official journal of the Society of Toxicology 20041201

• Reduced-intensity conditioning using TBI (8 Gy), fludarabine, cyclophosphamide and ATG in elderly CML patients provides excellent results especially when performed in the early course of the disease.

  Bone marrow transplantation 20041201

• Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer.

  The journal of gene medicine 20041201

• The influence of farnesyl protein transferase inhibitor R115777 (Zarnestra) alone and in combination with purine nucleoside analogs on acute myeloid leukemia progenitors in vitro.

  European journal of haematology 20041201

• Functional analysis of the murine Emr1 promoter identifies a novel purine-rich regulatory motif required for high-level gene expression in macrophages.

  Genomics 20041201

• Structure of a purine-purine wobble base pair in the decoding center of the ribosome.

  Nature structural & molecular biology 20041201

• Receptor regulatory properties evident in the molecular similarity of serotonin receptor ligands and purine nucleotides.

  The Journal of pharmacy and pharmacology 20041201

• Mapping of the bovine genes of the de novo AMP synthesis pathway.

  Animal genetics 20041201

• Pentostatin - pharmacology, immunology, and clinical effects in graft-versus-host disease.

  Expert opinion on pharmacotherapy 20041201

• Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels.

  The European journal of neuroscience 20041201

• MTHFR polymorphisms, diet, HRT, and breast cancer risk: the multiethnic cohort study.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041201

• Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.

  Chemistry & biology 20041201

• Drosophila melanogaster Prat, a purine de novo synthesis gene, has a pleiotropic maternal-effect phenotype.

  Genetics 20041201

• Purine receptors: GPCR structure and agonist design.

  Molecular interventions 20041201

• Immunomodulatory therapy for inflammatory bowel disease.

  Journal of gastroenterology 20041201

• Transport of endogenous nucleosides in guinea pig heart.

  Canadian journal of physiology and pharmacology 20041201

• The vascular endothelial growth factor-induced disruption of gap junctions is relayed by an autocrine communication via ATP release in coronary capillary endothelium.

  Annals of the New York Academy of Sciences 20041201

• Does asymptomatic hyperuricaemia contribute to the development of renal and cardiovascular disease? An old controversy renewed.

  Nephrology (Carlton, Vic.) 20041201

• Purine nucleotides and their metabolites in erythrocytes of streptozotocin diabetic rats.

  Diabetes & metabolism 20041201

• [Composition of renal stones currently observed in non-industrialized countries].

  Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20041201

• P2Y receptors and pain transmission.

  Purinergic signalling 20041201

• P2 receptors are involved in the mediation of motivation-related behavior.

  Purinergic signalling 20041201

• Regulation of neuronal ion channels via P2Y receptors.

  Purinergic signalling 20041201

• Coronary artery reperfusion: The ADP receptor P2Y(1) mediates early reactive hyperemia in vivo in pigs.

  Purinergic signalling 20041201

• Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.

  Circulation research 20041126

• Pd-catalyzed amination of nucleoside arylsulfonates to yield N6-aryl-2,6-diaminopurine nucleosides.

  Angewandte Chemie (International ed. in English) 20041126

• Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K.

  Journal of medicinal chemistry 20041118

• Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine.

  Nature 20041118

• Shift in purine/pyrimidine base recognition upon exchanging extracellular domains in P2Y 1/6 chimeric receptors.

  Biochemical pharmacology 20041115

• Crystallographic structure of PNP from Mycobacterium tuberculosis at 1.9A resolution.

  Biochemical and biophysical research communications 20041112

• A facile and efficient synthesis of (Purin-6-yl)alanines.

  The Journal of organic chemistry 20041112

• Synthesis and degradation of nucleobases and nucleic acids by formamide in the presence of montmorillonites.

  Chembiochem : a European journal of chemical biology 20041105

• Dynamics in the U6 RNA intramolecular stem-loop: a base flipping conformational change.

  Biochemistry 20041102

• Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5).

  Neurochemistry international 20041101

• Methylthioadenosine.

  The international journal of biochemistry & cell biology 20041101

• Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts.

  The international journal of biochemistry & cell biology 20041101

• Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus.

  Gene therapy 20041101

• Broad specificity of human phosphoglycerate kinase for antiviral nucleoside analogs.

  Biochemical pharmacology 20041101

• Membrane permeation characteristics of abacavir in human erythrocytes and human T-lymphoblastoid CD4+ CEM cells: comparison with (-)-carbovir.

  Biochemical pharmacology 20041101

• Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases.

  Biochemical pharmacology 20041101

• Nutritional requirements of Lactobacillus delbrueckii subsp. lactis in a chemically defined medium.

  Current microbiology 20041101

• Simultaneous determination of multiple constituents in real beer samples of different origins by capillary zone electrophoresis.

  Analytical and bioanalytical chemistry 20041101

• Axiom of determining transcription start points by RNA polymerase in Escherichia coli.

  Molecular microbiology 20041101

• Protein thiol modifications visualized in vivo.

  PLoS biology 20041101

• Unanticipated antigens: translation initiation at CUG with leucine.

  PLoS biology 20041101

• A pilot trial of rituximab and alemtuzumab combination therapy in patients with relapsed and/or refractory chronic lymphocytic leukemia (CLL).

  Leukemia & lymphoma 20041101

• [Synthesis of phosphonic acid and phosphinic acid derivatives for development of biologically active compounds].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041101

• Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation.

  The Journal of pediatrics 20041101

• Coordination mode and oxidation susceptibility of nickel(II) complexes with 2'-deoxyguanosine 5'-monophosphate and l-histidine.

  Journal of inorganic biochemistry 20041101

• Water-soluble platinum(II) complexes of diamine chelating ligands bearing amino-acid type substituents: the effect of the linked amino acid and the diamine chelate ring size on antitumor activity, and interactions with 5'-GMP and DNA.

  Journal of inorganic biochemistry 20041101

• GMP and AMP as methyl radical traps in the reaction with pentaamminemethylcobalt(III).

  Journal of inorganic biochemistry 20041101

• Determinants of selectivity in alkylation of nucleosides and DNA by secondary diazonium ions: evidence for, and consequences of, a preassociation mechanism.

  Chemical research in toxicology 20041101

• Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.

  Yeast (Chichester, England) 20041101

• Etched chemically modified capillaries: novel separation media for electrophoretic analyses.

  Journal of separation science 20041101

• Current management of gout in patients unresponsive or allergic to allopurinol.

  Joint, bone, spine : revue du rhumatisme 20041101

• Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell lines.

  Environmental health perspectives 20041101

• [Purine nucleoside phosphorylase (PNP)].

  Nihon rinsho. Japanese journal of clinical medicine 20041101

• Translational research with pemetrexed in breast cancer.

  Oncology (Williston Park, N.Y.) 20041101

• Bias explorer: measurements of compositional bias in EMBL and GenBank sequence files.

  Antonie van Leeuwenhoek 20041101

• The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia.

  Folia morphologica 20041101

• [Raman spectroscopic study on the influence of ultraviolet radiation on calf thymus DNA in aqueous solution].

  Guang pu xue yu guang pu fen xi = Guang pu 20041101

• Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function.

  Hypertension research : official journal of the Japanese Society of Hypertension 20041101

• Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart.

  Journal of cardiovascular pharmacology 20041101

• Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 3rd communication. Behaviour of 5-amino-1H-imidazole-4-carbonitrile derivatives.

  Chemistry & biodiversity 20041101

• Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation.

  British journal of cancer 20041018

• Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP.

  Journal of molecular biology 20041015

• Gas-phase acidity studies of multiple sites of adenine and adenine derivatives.

  The Journal of organic chemistry 20041015

• Factors affecting thermodynamic stabilities of RNA 3 x 3 internal loops.

  Biochemistry 20041012

• Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

• Specific and non-specific purine trap in the T-loop of normal and suppressor tRNAs.

  Journal of molecular biology 20041008

• Halogenated 7-deazapurine nucleosides: stereoselective synthesis and conformation of 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides.

  Organic & biomolecular chemistry 20041007

• Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication.

  Journal of medicinal chemistry 20041007

• Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues.

  European journal of pharmacology 20041006

• Binding of DNA purine sites to dirhodium compounds probed by mass spectrometry.

  Inorganic chemistry 20041004

• Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family.

  The Biochemical journal 20041001

• DUK114, the Drosophila orthologue of bovine brain calpain activator protein, is a molecular chaperone.

  The Biochemical journal 20041001

• Investigation on the causes of codon and amino acid usages variation between thermophilic Aquifex aeolicus and mesophilic Bacillus subtilis.

  Journal of biomolecular structure & dynamics 20041001

• Conformational analysis of canonical 2-deoxyribonucleotides. 2. Purine nucleotides.

  Journal of biomolecular structure & dynamics 20041001

• Measurement of DNA adducts in cells exposed to cisplatin.

  Analytical biochemistry 20041001

• New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.

  Current opinion in pharmacology 20041001

• Structure-activity relationship of phosmidosine: importance of the 7,8-dihydro-8-oxoadenosine residue for antitumor activity.

  Bioorganic & medicinal chemistry 20041001

• The influence of DNA stiffness upon nucleosome formation.

  Journal of structural biology 20041001

• Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes.

  Journal of molecular biology 20041001

• Acute myeloid leukemia following treatment with cladribine for hairy cell leukemia: a case report and review of the literature.

  Leukemia & lymphoma 20041001

• Kupffer cell depletion attenuates superoxide anion release into the hepatic sinusoids after lipopolysaccharide treatment.

  Journal of gastroenterology and hepatology 20041001

• Reducing concentrate supplementation in dairy cow diets while maintaining milk production with pea-wheat intercrops.

  Journal of dairy science 20041001

• Characterization of pco-1, a newly identified gene which regulates purine catabolism in Neurospora.

  Current genetics 20041001

• A comprehensive proteome map of growing Bacillus subtilis cells.

  Proteomics 20041001

• Identification and characterization of a novel gene of grouper iridovirus encoding a purine nucleoside phosphorylase.

  The Journal of general virology 20041001

• Proteomic basis for the possible use of lymphocytes for metabolic screenings.

  Amino acids 20041001

• Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes.

  Journal of inorganic biochemistry 20041001

• Ecto-5'-nucleotidase activity in brain membranes of zebrafish (Danio rerio).

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20041001

• The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.

  Arthritis and rheumatism 20041001

• Ruminal fermentation and degradation patterns, protozoa population and urinary purine derivatives excretion in goats and wethers fed diets based on olive leaves.

  Journal of animal science 20041001

• Development of ectopic roots from abortive nodule primordia.

  Molecular plant-microbe interactions : MPMI 20041001

• Identification of Leishmania strains from Jordan.

  Annals of tropical medicine and parasitology 20041001

• Purine nucleoside phosphorylase activity in rat cerebrospinal fluid.

  Neurochemical research 20041001

• Redox state of endogenous coenzyme q modulates the inhibition of linoleic acid-induced uncoupling by guanosine triphosphate in isolated skeletal muscle mitochondria.

  Journal of bioenergetics and biomembranes 20041001

• Exogenous nucleosides are required for the morphogenesis of the human filarial parasite Brugia malayi.

  The Journal of parasitology 20041001

• Purine and pyrimidine metabolism: new challenges.

  Nucleosides, nucleotides & nucleic acids 20041001

• Purine modulation of cytokine release during diuretic therapy of rheumatoid arthritis.

  Nucleosides, nucleotides & nucleic acids 20041001

• Clinical and biochemical manifestations and molecular characterization of the mutation HPRT Jerusalem.

  Nucleosides, nucleotides & nucleic acids 20041001

• Nucleotide degradation products in cerebrospinal fluid (CSF) in inherited and acquired pathologies.

  Nucleosides, nucleotides & nucleic acids 20041001

• Severe impairment of nucleotide synthesis through inhibition of mitochondrial respiration.

  Nucleosides, nucleotides & nucleic acids 20041001

• Liver transplant: adenosine metabolism and apoptosis.

  Nucleosides, nucleotides & nucleic acids 20041001

• Immucillins as antibiotics for T-cell proliferation and malaria.

  Nucleosides, nucleotides & nucleic acids 20041001

• Novel mutations and hot-spots in patients with purine nucleoside phosphorylase deficiency.

  Nucleosides, nucleotides & nucleic acids 20041001

• Selective transport of a new class of purine antimetabolites by the protozoan parasite Trypanosoma brucei.

  Nucleosides, nucleotides & nucleic acids 20041001

• Metabolism of adenosine in human colorectal tumour.

  Nucleosides, nucleotides & nucleic acids 20041001

• Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates.

  Biochemistry 20040928

• Enhancing Hoogsteen interactions: a pyrrole-containing purine nucleoside that competes with guanosine self-assembly.

  Journal of the American Chemical Society 20040922

• Stability of RNA hairpin loops closed by AU base pairs.

  Biochemistry 20040921

• Human UP1 as a model for understanding purine recognition in the family of proteins containing the RNA recognition motif (RRM).

  Journal of molecular biology 20040917

• Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.

  Journal of molecular biology 20040917

• Azoles as Suzuki cross-coupling leaving groups: syntheses of 6-arylpurine 2'-deoxynucleosides and nucleosides from 6-(imidazol-1-yl)- and 6-(1,2,4-triazol-4-yl)purine derivatives.

  Organic letters 20040916

• Voltammetric determination of all DNA nucleotides.

  Analytical biochemistry 20040915

• Comprehensive analysis of the 9p21 region in neuroblastoma suggests a role for genes mapping to 9p21-23 in the biology of favourable stage 4 tumours.

  British journal of cancer 20040913

• A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours.

  British journal of cancer 20040913

• Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids.

  The Journal of biological chemistry 20040910

• Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase.

  The Journal of biological chemistry 20040910

• Structural bioinformatics study of PNP from Schistosoma mansoni.

  Biochemical and biophysical research communications 20040910

• Design, synthesis, and biological evaluation of 1,2,3,7-tetrahydro-6h-purin-6-one and 3,7-dihydro-1h-purine-2,6-dione derivatives as corticotropin-releasing factor(1) receptor antagonists.

  Journal of medicinal chemistry 20040909

• One-dimensional oxalato-bridged Cu(II), Co(II), and Zn(II) complexes with purine and adenine as terminal ligands.

  Inorganic chemistry 20040906

• The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth.

  Biochimica et biophysica acta 20040906

• The purine transferase from Trypanosoma cruzi as a potential target for bisphosphonate-based chemotherapeutic compounds.

  Bioorganic & medicinal chemistry letters 20040906

• Synthesis of 3'-fluoro-2',3'-dideoxy-2',3'-didehydro-4'-ethynyl-D- and -L-furanosyl nucleosides.

  The Journal of organic chemistry 20040903

• Acute lymphoblastic leukemia with TEL-AML1 fusion has lower expression of genes involved in purine metabolism and lower de novo purine synthesis.

  Blood 20040901

• Quantitative analysis of liver protein expression during hibernation in the golden-mantled ground squirrel.

  Molecular & cellular proteomics : MCP 20040901

• Activation of P2 nucleotide receptors stimulates acid efflux from astrocytes.

  Glia 20040901

• Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06.

  Biochemical pharmacology 20040901

• Identification of the P2Y(12) receptor in nucleotide inhibition of exocytosis from bovine chromaffin cells.

  Molecular pharmacology 20040901

• Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20040901

• The role of fludarabine in the treatment of follicular and mantle cell lymphoma.

  Cancer 20040901

• 6-(4-Methoxybenzylamino)purin-3-ium chloride.

  Acta crystallographica. Section C, Crystal structure communications 20040901

• Effect of molasses supplementation on the production of lactating dairy cows fed diets based on alfalfa and corn silage.

  Journal of dairy science 20040901

• Effect of lead ions on rat erythrocyte purine content.

  Biological trace element research 20040901

• Effect of testosterone on purine nucleotide metabolism in rat liver.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040901

• Disturbances of purine nucleotide metabolism in uremia.

  Seminars in nephrology 20040901

• [Physiology and biochemistry of uric acid].

  Therapeutische Umschau. Revue therapeutique 20040901

• Gene therapy for adenosine-deaminase-deficient severe combined immunodeficiency.

  Best practice & research. Clinical haematology 20040901

• Sequence features of Oxytricha trifallax (class Spirotrichea) macronuclear telomeric and subtelomeric sequences.

  Protist 20040901

• [New perspectives in the evolution of prognosis and treatment of chronic lymphocytic leukaemia].

  Orvosi hetilap 20040829

• Improved antiviral activity of the aryloxymethoxyalaninyl phosphoramidate (APA) prodrug of abacavir (ABC) is due to the formation of markedly increased carbovir 5'-triphosphate metabolite levels.

  FEBS letters 20040827

• Mercaptoheterocyclic ligands grafted on a poly(ethylene vinyl alcohol) membrane for the purification of immunoglobulin G in a salt independent thiophilic chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040825

• Conformationally constrained purine mimics. Incorporation of adenine and guanine into spirocyclic nucleosides.

  The Journal of organic chemistry 20040820

• SNAr iodination of 6-chloropurine nucleosides: aromatic Finkelstein reactions at temperatures below -40 degrees C.

  Organic letters 20040819

• Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography.

  Biochemistry 20040817

• A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex.

  Biochemistry 20040817

• Activating the phosphate nucleophile at the catalytic site of purine nucleoside phosphorylase: a vibrational spectroscopic study.

  Journal of the American Chemical Society 20040811

• Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation.

  Journal of the American Chemical Society 20040811

• Structural and energetic consequences of expanding a highly cooperative stable DNA hairpin loop.

  Journal of the American Chemical Society 20040811

• Stacking-unstacking dynamics of oligodeoxynucleotide trimers.

  Biochemistry 20040810

• Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates.

  The Journal of biological chemistry 20040806

• Exploring Hoogsteen and reversed-Hoogsteen duplex and triplex formation with tricyclo-DNA purine sequences.

  Chembiochem : a European journal of chemical biology 20040806

• Epitaxial relationships between uric acid crystals and mineral surfaces: a factor in urinary stone formation.

  Langmuir : the ACS journal of surfaces and colloids 20040803

• Partial B-to-A DNA transition upon minor groove binding of protein Sac7d monitored by Raman spectroscopy.

  Biochemistry 20040803

• In vitro assessment of nucleoside analogs in multiple myeloma.

  Cancer chemotherapy and pharmacology 20040801

• Treatment of T-cell non-Hodgkin's lymphoma.

  Current treatment options in oncology 20040801

• Characterization of purine receptors in mouse thoracic aorta.

  Journal of cardiovascular pharmacology 20040801

• A reassessment of the response of the bacterial ribosome to the frameshift stimulatory signal of the human immunodeficiency virus type 1.

  RNA (New York, N.Y.) 20040801

• Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion.

  Journal of neurochemistry 20040801

• Exclusion of galectin 9 as a candidate gene for hyperuricosuria in the Dalmatian dog.

  Animal genetics 20040801

• Coordination mode of adenosine 5'-diphosphate in ternary systems containing Cu(II), Cd(II) or Hg(II) ions and polyamines.

  Journal of inorganic biochemistry 20040801

• Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.

  Acta crystallographica. Section D, Biological crystallography 20040801

• Global changes in transcription orchestrate metabolic differentiation during symbiotic nitrogen fixation in Lotus japonicus.

  The Plant journal : for cell and molecular biology 20040801

• Proteomic response to amino acid starvation in Candida albicans and Saccharomyces cerevisiae.

  Proteomics 20040801

• Early central nervous system complications after reduced-intensity stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040801

• Structure of Escherichia coli AMP nucleosidase reveals similarity to nucleoside phosphorylases.

  Structure (London, England : 1993) 20040801

• Maternal plasma hypoxanthine levels in nonpreeclamptic twin pregnancies.

  The Tohoku journal of experimental medicine 20040801

• Interaction between intrathecal gabapentin and adenosine in the formalin test of rats.

  Journal of Korean medical science 20040801

• 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.

  Chemical research in toxicology 20040801

• The regenerative plasticity of isolated urodele myofibers and its dependence on MSX1.

  PLoS biology 20040801

• Unraveling the molecular basis for regenerative cellular plasticity.

  PLoS biology 20040801

• Human sebaceous glands engage in aerobic glycolysis and glutaminolysis.

  The British journal of dermatology 20040801

• Role of low-dose 2-CdA in refractory or resistant lymphoplasmocytic lymphoma.

  Journal of chemotherapy (Florence, Italy) 20040801

• Urinary excretion of purine derivatives as an index of microbial protein synthesis in the camel (Camelus dromedarius).

  The British journal of nutrition 20040801

• [Study on beverages and kidney stone disease].

  Hinyokika kiyo. Acta urologica Japonica 20040801

• A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle.

  Molecular and biochemical parasitology 20040801

• Enzymatic transesterification of purine nucleoside having a low solubility in organic medium.

  Biotechnology letters 20040801

• Genomic-scale analysis of bacterial gene and protein expression in the host.

  Emerging infectious diseases 20040801

• Effect of insulin on spontaneous and progesterone-induced GVBD on Bufo arenarum denuded oocytes.

  Zygote (Cambridge, England) 20040801

• Identification of protein coding regions of rice genes using alternative spectral rotation measure and linear discriminant analysis.

  Genomics, proteomics & bioinformatics 20040801

• Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii.

  The Journal of biological chemistry 20040723

• A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases.

  Molecular cell 20040723

• Changes in purine levels and adenosine receptors in kindled seizures in the rat.

  Neuroreport 20040719

• Two metal ions coordinated to a purine residue tolerate each other well.

  Angewandte Chemie (International ed. in English) 20040719

• QSAR of adenosine receptor antagonists. Part 3: Exploring physicochemical requirements for selective binding of 1,2,4-triazolo[5,1-i]purine derivatives with human adenosine A3 receptor subtype.

  Bioorganic & medicinal chemistry letters 20040716

• Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases.

  Journal of immunology (Baltimore, Md. : 1950) 20040715

• A nucleic acid biosensor for gene expression analysis in nanograms of mRNA.

  Analytical chemistry 20040715

• The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action.

  The Journal of biological chemistry 20040709

• Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.

  The Journal of biological chemistry 20040709

• Adenosine uptake inhibitors.

  European journal of pharmacology 20040708

• Conformational properties of shape modified nucleosides--fleximers.

  Journal of the American Chemical Society 20040707

• Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanosine adduct, 3-(2'-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)-one.

  Journal of the American Chemical Society 20040707

• Esterase activity as a novel parameter of spore germination in Bacillus anthracis.

  Biochemical and biophysical research communications 20040702

• Mycophenolate mofetil treatment following renal transplantation decreases GTP concentrations in mononuclear leucocytes.

  Clinical science (London, England : 1979) 20040701

• Medical approaches and future options in chronic active ulcerative colitis.

  International journal of colorectal disease 20040701

• P2Y purine receptor responses and expression in the pulmonary circulation of juvenile rabbits.

  American journal of physiology. Heart and circulatory physiology 20040701

• Molecular and functional aspects of human cysteinyl leukotriene receptors.

  Pharmacological research 20040701

• Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding.

  Cancer gene therapy 20040701

• Trichomonas vaginalis: cytochemical localization of a NTPDase1 and an ecto-5'-nucleotidase and effects of adenine nucleotides on cellular viability.

  Parasitology research 20040701

• A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity.

  Archives of biochemistry and biophysics 20040701

• The clinical and epidemiological burden of chronic lymphocytic leukaemia.

  European journal of cancer care 20040701

• Metabolic risk factors and the impact of medical therapy on the management of nephrolithiasis in obese patients.

  The Journal of urology 20040701

• Oxaliplatin/rituximab combination in the treatment of intermediate-low grade non-Hodgkin's lymphoma of elderly patients.

  Oncology reports 20040701

• Steady-state kinetics of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi.

  Biochimica et biophysica acta 20040701

• Treatment with the purine synthesis inhibitor mizoribine for ANCA-associated renal vasculitis.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20040701

• Towards the pharmacotherapy of hairy cell leukaemia.

  Expert opinion on pharmacotherapy 20040701

• Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior.

  The American journal of pathology 20040701

• Mining the proteome.

  Nature 20040701

• Advances in chemotherapy for chronic lymphocytic leukemia.

  Seminars in hematology 20040701

• A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells.

  Molecular therapy : the journal of the American Society of Gene Therapy 20040701

• [Hairy cell leukemia therapy by cladribine].

  Nihon rinsho. Japanese journal of clinical medicine 20040701

• Ruminal fermentation and degradation patterns, protozoa population, and urinary purine derivatives excretion in goats and wethers fed diets based on two-stage olive cake: effect of PEG supply.

  Journal of animal science 20040701

• A comparison of purine derivatives excretion with conventional methods as indices of microbial yield in dairy cows.

  Journal of dairy science 20040701

• [Cladribine monotherapy for patients with relapsed or refractory indolent non-Hodgkin lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20040701

• Altered circadian relationship between serum nitric oxide, carbon dioxide, and uric acid in multiple sclerosis.

  Chronobiology international 20040701

• Medical therapy of Crohn disease.

  Current opinion in gastroenterology 20040701

• The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site.

  The Journal of biological chemistry 20040625

• Controlled transcriptional regulation in eukaryotes by a novel transcription factor derived from Escherichia coli purine repressor.

  Biochemical and biophysical research communications 20040625

• Structure-based design, synthesis, and antimicrobial activity of purine derived SAH/MTA nucleosidase inhibitors.

  Bioorganic & medicinal chemistry letters 20040621

• Synthesis and in vitro antimicrobial activities of 2-hydroxy-6-methyl-7-(arylamino)-1,7-dihydropurin-8-ones.

  Bioorganic & medicinal chemistry 20040615

• Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds.

  Bioorganic & medicinal chemistry 20040615

• Correlation of an adenine-specific conformational change with the ATP-dependent peptidase activity of Escherichia coli Lon.

  Biochemistry 20040615

• Biosynthesis of tetrahydrofolate in plants: crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class.

  Journal of molecular biology 20040611

• Binding causes the remote [5'-3H]thymidine kinetic isotope effect in human thymidine phosphorylase.

  Journal of the American Chemical Society 20040609

• Identification of purine inhibitors of phosphodiesterase 7 (PDE7).

  Bioorganic & medicinal chemistry letters 20040607

• Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20040604

• Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.

  Journal of medicinal chemistry 20040603

• High incidence of complications after 2-chloro-2'-deoxyadenosine combined with cyclophosphamide in patients with advanced lymphoproliferative malignancies.

  Annals of hematology 20040601

• Purine and pyrimidine metabolism and electrocortical brain activity during hypoxemia in near-term lambs.

  Pediatric research 20040601

• Microanalysis of DNA by stripping transfer voltammetry.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040601

• AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC.

  American journal of human genetics 20040601

• Waldenström macroglobulinemia.

  Current treatment options in oncology 20040601

• Cloning, expression, and purification of 5,10-methenyltetrahydrofolate synthetase from Mus musculus.

  Protein expression and purification 20040601

• Purinergic signalling in the lung: important in asthma and COPD?

  Current opinion in pharmacology 20040601

• Multiple functions for the invariant AGC triad of U6 snRNA.

  RNA (New York, N.Y.) 20040601

• Plasma purine nucleoside phosphorylase in cancer patients.

  Clinica chimica acta; international journal of clinical chemistry 20040601

• Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.

  European journal of biochemistry 20040601

• Saturation mutagenesis, complement selection, and steady-state kinetic studies illuminate the roles of invariant residues in active site loop I of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi.

  Biochimica et biophysica acta 20040601

• Effect of sauna bathing and beer ingestion on plasma concentrations of purine bases.

  Metabolism: clinical and experimental 20040601

• Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy.

  Therapeutic drug monitoring 20040601

• In silico prediction models for blood-brain barrier permeation.

  Current medicinal chemistry 20040601

• Formation of 'non-culturable' cells of Mycobacterium smegmatis in stationary phase in response to growth under suboptimal conditions and their Rpf-mediated resuscitation.

  Microbiology (Reading, England) 20040601

• Case report: the Lesch-Nyhan syndrome.

  European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry 20040601

• [Disorder of purine metabolism].

  Nihon rinsho. Japanese journal of clinical medicine 20040601

• Direct multicomponent analysis of beer samples constituents using micellar electrokinetic capillary chromatography.

  Electrophoresis 20040601

• Purine nucleoside antimetabolites in development for the treatment of cancer.

  Current opinion in investigational drugs (London, England : 2000) 20040601

• [Purine metabolism in patients with renal failure].

  Nihon rinsho. Japanese journal of clinical medicine 20040601

• [Xanthinuria with xanthine lithiasis in a patient with Lesch-Nyhan syndrome under allopurinol therapy].

  Aktuelle Urologie 20040601

• Physiology of folate and vitamin B12 in health and disease.

  Nutrition reviews 20040601

• Distinctive expression of Myf5 in relation to differentiation and plasticity of newt muscle cells.

  The International journal of developmental biology 20040601

• A novel class of phosphonate nucleosides. 9-[(1-phosphonomethoxycyclopropyl)methyl]guanine as a potent and selective anti-HBV agent.

  Journal of medicinal chemistry 20040520

• HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea.

  Journal of agricultural and food chemistry 20040519

• Structural comparison of MTA phosphorylase and MTA/AdoHcy nucleosidase explains substrate preferences and identifies regions exploitable for inhibitor design.

  Biochemistry 20040511

• Sequence-dependent thermodynamic parameters for locked nucleic acid (LNA)-DNA duplex formation.

  Biochemistry 20040511

• Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.

  The Journal of biological chemistry 20040507

• Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors.

  Life sciences 20040507

• Ureide biosynthesis in legume nodules.

  Frontiers in bioscience : a journal and virtual library 20040501

• Purine and pyrimidine nucleotide synthesis and degradation during in vitro morphogenesis of white spruce (Picea glauca).

  Frontiers in bioscience : a journal and virtual library 20040501

• Applying high throughput techniques in the study of adenosine kinase in plant metabolism and development.

  Frontiers in bioscience : a journal and virtual library 20040501

• Molecular analysis of 'de novo' purine biosynthesis in solanaceous species and in Arabidopsis thaliana.

  Frontiers in bioscience : a journal and virtual library 20040501

• Caffeine synthase and related methyltransferases in plants.

  Frontiers in bioscience : a journal and virtual library 20040501

• Distribution and biosynthesis of caffeine in plants.

  Frontiers in bioscience : a journal and virtual library 20040501

• Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies.

  Bone marrow transplantation 20040501

• Endotoxin challenge increases xanthine oxidase activity in cattle: effect of growth hormone and vitamin E treatment.

  Domestic animal endocrinology 20040501

• Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.

  Leukemia research 20040501

• The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes.

  Glia 20040501

• Determinants of plant U12-dependent intron splicing efficiency.

  The Plant cell 20040501

• Dipyridamole protects the liver against warm ischemia and reperfusion injury.

  Journal of the American College of Surgeons 20040501

• Potential role for the sorbitol pathway in the meiotic dysfunction exhibited by oocytes from diabetic mice.

  Journal of experimental zoology. Part A, Comparative experimental biology 20040501

• Cleavage reactions of the complex ions derived from self-complementary deoxydinucleotides and alkali-metal ions using positive ion electrospray ionization with tandem mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20040501

• Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner.

  The European journal of neuroscience 20040501

• Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy.

  Structure (London, England : 1993) 20040501

• Product analyses of ozone mediated nitration of benzimidazole derivatives with nitrogen dioxide: formation of 1-nitrobenzimidazoles and conversion to benzotriazoles.

  Chemical & pharmaceutical bulletin 20040501

• Studies on the mechanism of action of xanthine oxidase.

  Journal of inorganic biochemistry 20040501

• Synthesis and X-ray study of the 6-(N-pyrrolyl)purine and thymine derivatives of 1-aminocyclopropane-1-carboxylic acid.

  The journal of peptide research : official journal of the American Peptide Society 20040501

• Medical therapy for ulcerative colitis 2004.

  Gastroenterology 20040501

• Plastid sequence evolution: a new pattern of nucleotide substitutions in the Cucurbitaceae.

  Journal of molecular evolution 20040501

• Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone.

  International journal of hematology 20040501

• Physiological roles of xanthine oxidoreductase.

  Drug metabolism reviews 20040501

• The potential of gene transfer into primary B-CLL cells using recombinant virus vectors.

  Leukemia & lymphoma 20040501

• Epstein-Barr virus positive large B-cell lymphoma arising in a patient previously treated with Cladribine for hairy cell leukemia.

  Leukemia & lymphoma 20040501

• The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death.

  Free radical research 20040501

• Antiviral therapy: nucleotide and nucleoside analogs.

  Clinics in liver disease 20040501

• Purine and pyrimidine metabolism, designed by Donald Nicholson: Commentary.

  Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20040501

• Redox studies of subunit interactivity in aerobic ribonucleotide reductase from Escherichia coli.

  The Journal of biological chemistry 20040430

• Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.

  The Journal of biological chemistry 20040430

• Asymmetric synthesis of novel thioiso dideoxynucleosides with exocyclic methylene as potential antiviral agents.

  The Journal of organic chemistry 20040430

• Efficient synthesis of an adenosine A2a agonist: glycosylation of 2-haloadenines and an N2-alkyl-6-chloroguanine.

  The Journal of organic chemistry 20040430

• Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.

  The Journal of biological chemistry 20040423

• An unsubstituted C2 hydrogen of adenine is critical and sufficient at the -11 position of a promoter to signal base pair deformation.

  The Journal of biological chemistry 20040423

• Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.

  Journal of medicinal chemistry 20040422

• Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5' end sequences complementary to domain # 17 on the 16S ribosomal RNA.

  Biochemical and biophysical research communications 20040416

• Leaving group activation by aromatic stacking: an alternative to general acid catalysis.

  Journal of molecular biology 20040416

• Sequence and pH effects of LNA-containing triple helix-forming oligonucleotides: physical chemistry, biochemistry, and modeling studies.

  Biochemistry 20040413

• Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus.

  Journal of molecular biology 20040409

• Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

  Journal of medicinal chemistry 20040408

• Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activities.

  The Journal of biological chemistry 20040402

• Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions.

  The Journal of biological chemistry 20040402

• Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors.

  Journal of cellular physiology 20040401

• Xanthine dehydrogenase and aldehyde oxidase impact plant hormone homeostasis and affect fruit size in 'Hass' avocado.

  Journal of plant research 20040401

• Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040401

• Proteomic determination of metabolic enzymes of the amnion cell: basis for a possible diagnostic tool?

  Proteomics 20040401

• Transcription of purine transporter genes is activated during the isotropic growth phase of Aspergillus nidulans conidia.

  Molecular microbiology 20040401

• Electrochemical coding of single-nucleotide polymorphisms by monobase-modified gold nanoparticles.

  Analytical chemistry 20040401

• Mutagenicities of 8-hydroxyguanine and 2-hydroxyadenine produced by reactive oxygen species.

  Biological & pharmaceutical bulletin 20040401

• Human DNA glycosylases involved in the repair of oxidatively damaged DNA.

  Biological & pharmaceutical bulletin 20040401

• A novel missense mutation, c.584A > C (Y195S), in two unrelated Argentine patients with hypoxanthine-guanine phosphoribosyl-transferase deficiency, neurological variant.

  Molecular genetics and metabolism 20040401

• Occurrence of a myelodysplastic syndrome (MDS) during first-line 2-chloro-deoxyadenosine (2-CDA) treatment of a low-grade gastrointestinal MALT lymphoma. Case report and review of the literature.

  Haematologica 20040401

• Aspergillus fumigatus: a rare cause of vertebral osteomyelitis.

  Haematologica 20040401

• Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia.

  Postgraduate medical journal 20040401

• The risk of cytomegalovirus infection in non-myeloablative peripheral stem cell transplantation compared with conventional bone marrow transplantation.

  Journal of Korean medical science 20040401

• The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men.

  Journal of Korean medical science 20040401

• Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.

  Current medicinal chemistry 20040401

• Waldenström's macroglobulinemia: prognostic factors and recent therapeutic advances.

  Clinical and experimental medicine 20040401

• Hematologic toxicity of immunosuppressive treatment.

  Transplantation proceedings 20040401

• Effect of purine-free low-malt liquor (happo-shu) on the plasma concentrations and urinary excretion of purine bases and uridine--comparison between purine-free and regular happo-shu.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040401

• Pharmacology and mechanism of action of pemetrexed.

  Clinical lung cancer 20040401

• Treatment of chronic lymphocytic leukemia.

  Seminars in oncology 20040401

• Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species: from mitochondria to nuclei.

  Annals of the New York Academy of Sciences 20040401

• Biosynthesis, accumulation and degradation of theobromine in developing Theobroma cacao fruits.

  Journal of plant physiology 20040401

• Inhibitory effect of pyrimidine and purine nucleotides on the multiplication of Babesia gibsoni: possible cause of low parasitemia and simultaneous reticulocytosis in canine babesiosis.

  The Journal of veterinary medical science 20040401

• For the record: the Francis Crick Archive at the Wellcome Library.

  Medical history 20040401

• Recombination resulting in virulence shift in avian influenza outbreak, Chile.

  Emerging infectious diseases 20040401

• Host factors and efficacy of antiretroviral treatment.

  The new microbiologica 20040401

• Mutational, NMR, and NH exchange studies of the tight and selective binding of 8-oxo-dGMP by the MutT pyrophosphohydrolase.

  Biochemistry 20040330

• Peroxynitrite formation from the simultaneous reduction of nitrite and oxygen by xanthine oxidase.

  FEBS letters 20040326

• C-H to N substitution dramatically alters the sequence-specific DNA alkylation, cytotoxicity, and expression of human cancer cell lines.

  Journal of the American Chemical Society 20040324

• Head-to-head (HH) and head-to-tail (HT) conformers of cis-bis guanine ligands bound to the [Re(CO)3]+ core.

  Inorganic chemistry 20040322

• Structure and K+ ion-dependent stability of a parallel-stranded DNA quadruplex containing a core A-tetrad.

  Organic & biomolecular chemistry 20040321

• Crystal structures of Escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium.

  Journal of molecular biology 20040319

• [Treatment of T-cell prolymphocytic leukemia with monoclonal anti- CD52 antibody (alemtuzumab].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040318

• Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.

  The Journal of physiology 20040316

• 5-N-Substituted-2-(substituted benzenesulphonyl) glutamines as antitumor agents. Part II: synthesis, biological activity and QSAR study.

  Bioorganic & medicinal chemistry 20040315

• Synthesis and biological evaluation of 6-substituted purine and 9-beta-d-ribofuranosyl purine analogues.

  Bioorganic & medicinal chemistry 20040315

• Deoxynucleic guanidine; synthesis and incorporation of purine nucleosides into positively charged DNG oligonucleotides.

  Bioorganic & medicinal chemistry 20040315

• Synthesis and duplex DNA recognition studies of oligonucleotides containing a ureido isoindolin-1-one homo-N-nucleoside. A comparison of host-guest and DNA recognition studies.

  Bioorganic & medicinal chemistry 20040315

• Synthesis of a potent transition-state inhibitor of 5'-deoxy-5'-methylthioadenosine phosphorylase.

  Journal of medicinal chemistry 20040311

• Uric acid and diet--insights into the epidemic of cardiovascular disease.

  The New England journal of medicine 20040311

• Purine-rich foods, dairy and protein intake, and the risk of gout in men.

  The New England journal of medicine 20040311

• Inhibitors of Civ1 kinase belonging to 6-aminoaromatic-2-cyclohexyldiamino purine series as potent anti-fungal compounds.

  Biochimica et biophysica acta 20040311

• Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.

  Biochemistry 20040309

• G-rich oligonucleotide inhibits the binding of a nuclear protein to the Ki-ras promoter and strongly reduces cell growth in human carcinoma pancreatic cells.

  Biochemistry 20040309

• Engineered delta ribozymes can simultaneously knock down the expression of the genes encoding uracil phosphoribosyltransferase and hypoxanthine-xanthine-guanine phosphoribosyltransferase in Toxoplasma gondii.

  International journal for parasitology 20040309

• Toxoplasma gondii: the model apicomplexan.

  International journal for parasitology 20040309

• Electrophysiological characterization of the human Na(+)/nucleoside cotransporter 1 (hCNT1) and role of adenosine on hCNT1 function.

  The Journal of biological chemistry 20040305

• Metal coordination and imine-amine hydrogen bonding as the source of strongly shifted adenine pKa values.

  Journal of the American Chemical Society 20040303

• Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene.

  The Biochemical journal 20040301

• Accumulation of 5-phosphoribosyl-1-pyrophosphate in human CCRF-CEM leukaemia cells treated with antifolates.

  The international journal of biochemistry & cell biology 20040301

• Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology.

  Pediatric research 20040301

• Molecular-genetic peculiarities of classical biotype Vibrio cholerae, the etiological agent of the last outbreak Asiatic cholera in Russia.

  Microbial pathogenesis 20040301

• Subcellular localization of adenine and xanthine phosphoribosyltransferases in Leishmania donovani.

  Molecular and biochemical parasitology 20040301

• Insect allantoinase: cDNA cloning, purification, and characterization of the native protein from the cat flea, Ctenocephalides felis.

  Insect biochemistry and molecular biology 20040301

• Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.

  RNA (New York, N.Y.) 20040301

• Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1.

  Molecular pharmacology 20040301

• Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells.

  Mutagenesis 20040301

• Antineuropathic effects of the antibiotic derivative spicamycin KRN5500.

  Pain medicine (Malden, Mass.) 20040301

• Recovering the true targets of specific ligands by virtual screening of the protein data bank.

  Proteins 20040301

• The effects of tiazofurin on basal and amphetamine-induced motor activity in rats.

  Pharmacology, biochemistry, and behavior 20040301

• Current approach to diagnosis and management of chronic lymphocytic leukemia.

  Mayo Clinic proceedings 20040301

• Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements.

  PLoS biology 20040301

• Uric acid: role in cardiovascular disease and effects of losartan.

  Current medical research and opinion 20040301

• Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis.

  Molecular cancer therapeutics 20040301

• Suicide gene/prodrug therapy for pancreatic adenocarcinoma by E. coli purine nucleoside phosphorylase and 6-methylpurine 2'-deoxyriboside.

  Pancreas 20040301

• Adenine auxotrophic mutants of Aspergillus oryzae: development of a novel transformation system with triple auxotrophic hosts.

  Bioscience, biotechnology, and biochemistry 20040301

• Drug-induced pulmonary infection.

  Clinics in chest medicine 20040301

• Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.

  European journal of cell biology 20040301

• Complexes of copper(II) with adenosine or guanosine nucleosides, nucleotides 5'-monophosphate, 2'-deoxynucleosides or 2'-deoxynucleotides 5'-monophosphate in aqueous solution.

  Annali di chimica 20040301

• Purine nucleoside phosphorylase inhibitors in T-cell malignancies.

  Current opinion in drug discovery & development 20040301

• The chemodiversity of purine as a constituent of natural products.

  Chemistry & biodiversity 20040301

• Nucleic acid synthesis in cancerous cells under the effect of gnidilatimonoein from Daphne mucronata.

  Life sciences 20040227

• Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs.

  Journal of molecular biology 20040227

• Synthesis of 2',5'-dideoxy-2-fluoroadenosine and 2',5'-dideoxy-2,5'-difluoroadenosine: potent P-site inhibitors of adenylyl cyclase.

  Journal of medicinal chemistry 20040226

• The assignment of downfield proton resonances in an enzyme inhibitor complex using time-dependent saturation transferred NOEs.

  Journal of the American Chemical Society 20040225

• Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.

  Biochemistry 20040224

• DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine.

  The Journal of biological chemistry 20040220

• One-electron attachment reaction of B- and Z-DNA modified by 8-bromo-2'-deoxyguanosine.

  The Journal of organic chemistry 20040220

• Simultaneous analysis of theanine, chlorogenic acid, purine alkaloids and catechins in tea samples with the help of multi-dimension information of on-line high performance liquid chromatography/electrospray-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20040218

• Triple helix forming TRIPside molecules that target mixed purine/pyrimidine DNA sequences.

  Biochemistry 20040217

• Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

  Biochemistry 20040217

• Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase.

  Biochemistry 20040217

• 2-ClATP exerts anti-tumoural actions not mediated by P2 receptors in neuronal and glial cell lines.

  Biochemical pharmacology 20040215

• Purine and pyrimidine-specific repression of the Escherichia coli carAB operon are functionally and structurally coupled.

  Journal of molecular biology 20040206

• Separation of purine and pyrimidine bases by capillary electrophoresis using beta-cyclodextrin as an additive.

  Journal of pharmaceutical and biomedical analysis 20040204

• The equilibrative nucleoside transporter family, SLC29.

  Pflugers Archiv : European journal of physiology 20040201

• The concentrative nucleoside transporter family, SLC28.

  Pflugers Archiv : European journal of physiology 20040201

• Interstitial purine metabolites in hearts with LV remodeling.

  American journal of physiology. Heart and circulatory physiology 20040201

• Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo.

  Leukemia research 20040201

• Xanthine nucleotide-specific G-protein alpha-subunits: a novel approach for the analysis of G-protein-mediated signal transduction.

  Naunyn-Schmiedeberg's archives of pharmacology 20040201

• The influence of diazepam and midazolam on adenosine-induced forearm vasodilation in humans.

  Journal of cardiovascular pharmacology 20040201

• The effect of maintenance immunosuppression medication on the change in kidney allograft function.

  Kidney international 20040201

• Flux coupling analysis of genome-scale metabolic network reconstructions.

  Genome research 20040201

• Solution, solid state and biological characterization of ruthenium(III)-DMSO complexes with purine base derivatives.

  Journal of inorganic biochemistry 20040201

• Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.

  Molecular pharmacology 20040201

• Angiostatin-induced inhibition of endothelial cell proliferation/apoptosis is associated with the down-regulation of cell cycle regulatory protein cdk5.

  Journal of cellular biochemistry 20040201

• Pentostatin (Nipent) in the treatment of chronic lymphocyte leukemia and hairy cell leukemia.

  Expert review of anticancer therapy 20040201

• A modified immuno-enriched 32P-postlabeling method for analyzing the malondialdehyde-deoxyguanosine adduct, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)one in human tissue samples.

  Chemical research in toxicology 20040201

• 1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum.

  Natural product research 20040201

• Adenosine deaminase 2 from chicken liver: purification, characterization, and N-terminal amino acid sequence.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040201

• Chronic lymphocytic leukaemia: up-dated recommendations on diagnosis and treatment.

  Onkologie 20040201

• Structure-based approaches to the development of novel anti-malarials.

  Current drug targets 20040201

• [Chronic lymphocytic leukemia--the old and the new].

  Therapeutische Umschau. Revue therapeutique 20040201

• Monoclonal antibodies in the treatment of chronic lymphoid leukemias.

  Leukemia & lymphoma 20040201

• A three-hybrid approach to scanning the proteome for targets of small molecule kinase inhibitors.

  Chemistry & biology 20040201

• Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.

  Journal of enzyme inhibition and medicinal chemistry 20040201

• Effect of caffeine on meiotic maturation of porcine oocytes.

  Zygote (Cambridge, England) 20040201

• Immobilized Escherichia coli BL21 as a catalyst for the synthesis of adenine and hypoxanthine nucleosides.

  Chemistry & biodiversity 20040201

• Distinct structural determinants of efficacy and sensitivity in the ligand-binding domain of cyclic nucleotide-gated channels.

  The Journal of biological chemistry 20040130

• The AzgA purine transporter of Aspergillus nidulans. Characterization of a protein belonging to a new phylogenetic cluster.

  The Journal of biological chemistry 20040130

• Crystal structure of fully ligated adenylosuccinate synthetase from Plasmodium falciparum.

  Journal of molecular biology 20040130

• Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes.

  Biochemistry 20040127

• Mechanical stimulation releases nucleotides that activate P2Y1 receptors to trigger neural reflex chloride secretion in guinea pig distal colon.

  The Journal of comparative neurology 20040126

• Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors.

  The Journal of comparative neurology 20040126

• Probing the solvent accessibility and electron density of adenine: oxidation of 7-deazaadenine in bent DNA and purine doublets.

  Inorganic chemistry 20040126

• Platinum complexes with NH groups on the carrier ligand and with only one guanine or hypoxanthine derivative. Informative models for assessing relative nucleobase and nucleotide hydrogen-bond interactions with amine ligands in solution.

  Inorganic chemistry 20040126

• Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase.

  Journal of molecular biology 20040123

• Structures of human purine nucleoside phosphorylase complexed with inosine and ddI.

  Biochemical and biophysical research communications 20040123

• Synthesis of chemically stabilized phosmidosine analogues and the structure--activity relationship of phosmidosine.

  The Journal of organic chemistry 20040123

• Selective formation of stable triplexes including a TA or a CG interrupting site with new bicyclic nucleoside analogues (WNA).

  Journal of the American Chemical Society 20040121

• Positive correlation between DNA polymerase alpha-primase pausing and mutagenesis within polypyrimidine/polypurine microsatellite sequences.

  Journal of molecular biology 20040116

• Estimation of guanine deaminase using guanosine as a 'prosubstrate'.

  Analytical biochemistry 20040115

• Capillary electrophoresis microchip with a carbon nanotube-modified electrochemical detector.

  Analytical chemistry 20040115

• CD26 expression correlates with a reduced sensitivity to 2'-deoxycoformycin-induced growth inhibition and apoptosis in T-cell leukemia/lymphomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040115

• Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.

  Biochemistry 20040113

• Synthesis and cytotoxicity of 9-(2-deoxy-2-alkyldithio-beta-D-arabinofuranosyl)purine nucleosides which are stable precursors to potential mechanistic probes of ribonucleotide reductases.

  Organic & biomolecular chemistry 20040107

• Microchip capillary electrophoresis with a boron-doped diamond electrode for rapid separation and detection of purines.

  Journal of chromatography. A 20040102

• Successful CD34+ cell mobilization by intermediate-dose Ara-C in chronic lymphocytic leukemia patients treated with sequential fludarabine and Campath-1H.

  Leukemia 20040101

• Ammonium-induced internalisation of UapC, the general purine permease from Aspergillus nidulans.

  Fungal genetics and biology : FG & B 20040101

• Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon.

  The Journal of comparative neurology 20040101

• Tumor sensitization to purine analogs by E. coli PNP.

  Methods in molecular medicine 20040101

• Current therapy of ulcerative colitis in children.

  Expert opinion on pharmacotherapy 20040101

• The class C acid phosphatase of Helicobacter pylori is a 5' nucleotidase.

  Protein expression and purification 20040101

• Dynamics of the IRE RNA hairpin loop probed by 2-aminopurine fluorescence and stochastic dynamics simulations.

  RNA (New York, N.Y.) 20040101

• Purine bases at position 37 of tRNA stabilize codon-anticodon interaction in the ribosomal A site by stacking and Mg2+-dependent interactions.

  RNA (New York, N.Y.) 20040101

• Antimycobacterial agents. 1. Thio analogues of purine.

  Journal of medicinal chemistry 20040101

• Treatment options for newly diagnosed patients with chronic lymphocytic leukemia.

  Current hematology reports 20040101

• Adenosine: an endogenous regulator of innate immunity.

  Trends in immunology 20040101

• The diurnal rhythm of adenosine levels in the basal forebrain of young and old rats.

  Neuroscience 20040101

• Genetic diversity and relationships in mulberry (genus Morus) as revealed by RAPD and ISSR marker assays.

  BMC genetics 20040101

• Gene-directed enzyme prodrug therapy for prostate cancer in a mouse model that imitates the development of human disease.

  The journal of gene medicine 20040101

• Adenine riboswitches and gene activation by disruption of a transcription terminator.

  Nature structural & molecular biology 20040101

• Identification and comparative analysis of components from the signal recognition particle in protozoa and fungi.

  BMC genomics 20040101

• Mobilization of xanthine oxidase from the gastrointestinal tract in acute pancreatitis.

  BMC gastroenterology 20040101

• Pharmacologic immunosuppression.

  Frontiers in bioscience : a journal and virtual library 20040101

• Inosine alleviates rat caerulein pancreatitis and pancreatitis-associated lung injury.

  Journal of gastroenterology 20040101

• Uric acid administration for neuroprotection in patients with acute brain ischemia.

  Medical hypotheses 20040101

• Peripheral blood mononuclear cell DNA 6-thioguanine metabolite levels correlate with decreased interferon-gamma production in patients with Crohn's disease on AZA therapy.

  Digestive diseases and sciences 20040101

• Radiation-induced DNA damage: formation, measurement, and biochemical features.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101

• Microwave-assisted organic synthesis using minivials to optimize and expedite the synthesis of diverse purine libraries.

  Journal of combinatorial chemistry 20040101

• Leaf senescence--not just a 'wear and tear' phenomenon.

  Genome biology 20040101

• [Effect of optimum jogging in a hot environment on uric acid metabolism].

  Nihon eiseigaku zasshi. Japanese journal of hygiene 20040101

• Nucleosides. IX. Synthesis of purine N(3),5'-cyclonucleosides and N(3),5'-cyclo-2',3'-seconucleosides via Mitsunobu reaction as TIBO-like derivatives.

  Nucleosides, nucleotides & nucleic acids 20040101

• Synthesis of nucleoside libraries on solid support. I. N2,N6-disubstituted diaminopurine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20040101

• Synthesis of nucleoside libraries on solid support. II. 2,6,8-Trisubstituted purine nucleosides using 8-bromoguanosine as precursor.

  Nucleosides, nucleotides & nucleic acids 20040101

• Mastocytosis: classification, diagnosis, and clinical presentation.

  Allergy and asthma proceedings 20040101

• Prediction of Saccharomyces cerevisiae replication origins.

  Genome biology 20040101

• Enriching for direct regulatory targets in perturbed gene-expression profiles.

  Genome biology 20040101

• Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488.

  Leukemia & lymphoma 20040101

• DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse.

  Environmental and molecular mutagenesis 20040101

• Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses.

  Antiviral chemistry & chemotherapy 20040101

• Molecular recognition at purine and pyrimidine nucleotide (P2) receptors.

  Current topics in medicinal chemistry 20040101

• Treatment options in chronic lymphocytic leukemia.

  The hematology journal : the official journal of the European Haematology Association 20040101

• Clinical experience with fludarabine in indolent non-Hodgkin's lymphoma.

  The hematology journal : the official journal of the European Haematology Association 20040101

• Treatment of hematological malignancies with allogeneic nonmyeloablative stem cell transplantation: conditioning regimens with fludarabine.

  The hematology journal : the official journal of the European Haematology Association 20040101

• Future prospects for fludarabine-containing regimens in the treatment of hematological cancers.

  The hematology journal : the official journal of the European Haematology Association 20040101

• Bacterial variations on the methionine salvage pathway.

  BMC microbiology 20040101

• Collisionally-induced dissociation of purine antiviral agents: mechanisms of ion formation using gas phase hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20040101

• New probes for microtubule dynamics.

  Chemistry & biology 20040101

• Identification of a novel protein regulating microtubule stability through a chemical approach.

  Chemistry & biology 20040101

• The over-representation of binary DNA tracts in seven sequenced chromosomes.

  BMC genomics 20040101

• Differential metabolic effects on mitochondria by silica hydride using capillary electrophoresis.

  Journal of medicinal food 20040101

• Mutation carrier testing in Lesch-Nyhan syndrome families: HPRT mutant frequency and mutation analysis with peripheral blood T lymphocytes.

  Genetic testing 20040101

• Characterization of a nudix hydrolase from Deinococcus radiodurans with a marked specificity for (deoxy)ribonucleoside 5'-diphosphates.

  BMC biochemistry 20040101

• Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene.

  BMC pharmacology 20040101

• New insights into erythropoiesis: the roles of folate, vitamin B12, and iron.

  Annual review of nutrition 20040101

• A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases.

  BMC bioinformatics 20040101

• Adenosine deaminase activity and its isoenzyme pattern in women with recurrent spontaneous abortions.

  Gynecologic and obstetric investigation 20040101

• Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase.

  Current topics in medicinal chemistry 20040101

• The biochemical basis of the neurobehavioral abnormalities in the Lesch-Nyhan syndrome: a hypothesis.

  Medical hypotheses 20040101

• Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20040101

• Creation of non-human primate neurogenetic disease models by gene targeting and nuclear transfer.

  Reproductive biology and endocrinology : RB&E 20040101

• Xanthine, xanthosine and its nucleotides: solution structures of neutral and ionic forms, and relevance to substrate properties in various enzyme systems and metabolic pathways.

  Acta biochimica Polonica 20040101

• Quantitative relationship between synonymous codon usage bias and GC composition across unicellular genomes.

  BMC evolutionary biology 20040101

• Clofarabine.

  Drugs in R&D 20040101

• Vascular physiology and pathology of circulating xanthine oxidoreductase: from nucleotide sequence to functional enzyme.

  Redox report : communications in free radical research 20040101

• Assembly of splicing complexes on exon 11 of the human insulin receptor gene does not correlate with splicing efficiency in-vitro.

  BMC molecular biology 20040101

• Systematic quantification of gene interactions by phenotypic array analysis.

  Genome biology 20040101

• Shotgun proteomics of Methanococcus jannaschii and insights into methanogenesis.

  Journal of proteome research 20040101

• Graph-based iterative Group Analysis enhances microarray interpretation.

  BMC bioinformatics 20040101

• [Similarity of mutation spectra of the mitochondrial DNA hypervariable segment 1 in Homo and Pan species].

  Molekuliarnaia biologiia 20040101

• Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms?

  Genome biology 20040101

• Enzyme activities controlling adenosine levels in normal and neoplastic tissues.

  Medical oncology (Northwood, London, England) 20040101

• Involvement of purinergic nerves in the NANC inhibitory junction potentials in pigeon oesophageal smooth muscle.

  Autonomic & autacoid pharmacology 20040101

• Regulatory role of E-NTPase/E-NTPDase in Ca2+/Mg2+ transport via gated channel.

  Theoretical biology & medical modelling 20040101

• Inheritance of urinary calculi in the Dalmatian.

  Journal of veterinary internal medicine 20040101

• Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells.

  Genome biology 20040101

• Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably?

  Retrovirology 20040101

• Complete mitochondrial genome sequence of Urechis caupo, a representative of the phylum Echiura.

  BMC genomics 20040101

• Simple statistical models predict C-to-U edited sites in plant mitochondrial RNA.

  BMC bioinformatics 20040101

• Regulation of milk lipid formation and secretion in the mouse mammary gland.

  Advances in experimental medicine and biology 20040101

• Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase.

  Respiratory research 20040101

• Genomic and proteomic adaptations to growth at high temperature.

  Genome biology 20040101

• AIT-082 and methylprednisolone singly, but not in combination, enhance functional and histological improvement after acute spinal cord injury in rats.

  International journal of immunopathology and pharmacology 20040101

• Purine analogs in leukemia.

  Advances in pharmacology (San Diego, Calif.) 20040101

• Strickler-Berg analysis of excited singlet state dynamics in DNA and RNA nucleosides.

  Faraday discussions 20040101

• [Thiaside diuretics in combination with inhibitors of angiotensin-converting enzyme in patients with diabetes mellitus type 2 comorbid with arterial hypertension].

  Terapevticheskii arkhiv 20040101

• New nucleoside analogs in the treatment of hematological disorders.

  Acta poloniae pharmaceutica 20040101

• Aetiological factors in paediatric urolithiasis.

  Nephron. Clinical practice 20040101

• Analysis of urinary nucleosides. IV. Identification of urinary purine nucleosides by liquid chromatography/electrospray mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20040101

• A probabilistic model for the evolution of RNA structure.

  BMC bioinformatics 20040101

• Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family.

  Molecular membrane biology 20040101

• Immobilization and stabilization of recombinant multimeric uridine and purine nucleoside phosphorylases from Bacillus subtilis.

  Biomacromolecules 20040101

• [Arterial hypertension in chronic glomerulonephritis: detectability and treatment efficacy].

  Terapevticheskii arkhiv 20040101

• Phylogenomic evidence supports past endosymbiosis, intracellular and horizontal gene transfer in Cryptosporidium parvum.

  Genome biology 20040101

• Consensus clustering and functional interpretation of gene-expression data.

  Genome biology 20040101

• Interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, and a bisubstrate analogue inhibitor: implications for the reaction mechanism.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• Amyloidosis and Waldenström's macroglobulinemia.

  Hematology. American Society of Hematology. Education Program 20040101

• The influence of 2-chlorodeoxyadenosine (2-CdA) on the adenine energy charge and glutathione content of human erythrocytes.

  Cell biology international 20040101

• Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovarian and breast cancer.

  BMC bioinformatics 20040101

• Estimating genomic coexpression networks using first-order conditional independence.

  Genome biology 20040101

• Neurotrophin and Trk expression by cells of the human lamina cribrosa following oxygen-glucose deprivation.

  BMC neuroscience 20040101

• Monoclonal antibodies in the treatment of chronic lymphocytic leukemia.

  Medical oncology (Northwood, London, England) 20040101

• [Acute renal failure and 2,8-dihydroxyadeninuria].

  Nephrologie 20040101

• A two-way interface between limited Systems Biology Markup Language and R.

  BMC bioinformatics 20040101

• Side-chain conformational restriction in template-competitive inhibitors of E. coli DNA polymerase I Klenow fragment: synthesis, structural characterization and inhibition activity.

  Nucleosides, nucleotides & nucleic acids 20040101

• Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach.

  BMC bioinformatics 20040101

• Effective anomerisation of 2'-deoxyadenosine derivatives during disaccharide nucleoside synthesis.

  Nucleosides, nucleotides & nucleic acids 20040101

• Synthesis of (-)-DAPD.

  Nucleosides, nucleotides & nucleic acids 20040101

• [Inherited disorders of purine and pyrimidine metabolism. State of art. Contribution for diagnosis].

  Acta medica portuguesa 20040101

• [The significance of free radicals and antioxidants due to the load induced by sport activity].

  Ceskoslovenska fysiologie 20040101

• [Principal infections in the oncology patient: practical treatment].

  Anales del sistema sanitario de Navarra 20040101

• Second malignancies and Richter's syndrome in patients with chronic lymphocytic leukemia.

  Hematology (Amsterdam, Netherlands) 20040101

• G-protein-coupled receptor signaling, RGS proteins, and lymphocyte function.

  Critical reviews in immunology 20040101

• [Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].

  Postepy biochemii 20040101

• Adenosine and adenine nucleotides as regulators of cerebral blood flow: roles of acidosis, cell swelling, and KATP channels.

  Critical reviews in neurobiology 20040101

• [Interaction of preparation 'ATP-LONG' with distearoylphosphatidylcholine monolayer].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101

• [Purine nucleotides of human erythrocytes--metabolism and regulation].

  Postepy biochemii 20040101

• Purine loading, stem-loops and Chargaff's second parity rule: a discussion of the application of elementary principles to early chemical observations.

  Applied bioinformatics 20040101

• Purine bases and atheromatous plaque.

  International journal of immunopathology and pharmacology 20040101

• Practical synthesis of 2'-deoxy-2'-fluoroarabinofuranosyl purine nucleosides by chemo-enzymatic method.

  Nucleic acids symposium series (2004) 20040101

• Effects of 5-substituted pyrimidine nucleoside bases of WNA on stability of triplex DNA.

  Nucleic acids symposium series (2004) 20040101

• Chemical synthesis of oxanine-contained oligodeoxynucleotides.

  Nucleic acids symposium series (2004) 20040101

• Uncoupling Proteins in Amoeboid Eukaryotes, Acanthamoeba castellanii, and Dictyostelium discoideum.

  Toxicology mechanisms and methods 20040101

• Perinatal asphyxia syndrome in the foal: review and a case report.

  Irish veterinary journal 20040101

• Cellular and molecular mechanisms in environmental and occupational inhalation toxicology.

  GMS current topics in otorhinolaryngology, head and neck surgery 20040101

• Toxicological assessment of noxious inhalants.

  GMS current topics in otorhinolaryngology, head and neck surgery 20040101

• Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres.

  Journal of the American Chemical Society 20031231

• Crystal structure of human PNP complexed with guanine.

  Biochemical and biophysical research communications 20031219

• Synthesis and biological evaluation of iodinated and fluorinated 9-(2-hydroxypropyl) and 9-(2-hydroxyethoxy)methyl purine nucleoside analogues.

  Journal of medicinal chemistry 20031218

• Synthesis and evaluation of optically pure dioxolanes as inhibitors of hepatitis C virus RNA replication.

  Bioorganic & medicinal chemistry letters 20031215

• Immunosuppression with FK778 and mycophenolate mofetil in a rat cardiac transplantation model.

  Transplantation 20031215

• Cytokinin-induced differentiation of human myeloid leukemia HL-60 cells is associated with the formation of nucleotides, but not with incorporation into DNA or RNA.

  Biochimica et biophysica acta 20031207

• Synthesis and molecular structure of new acyclic analogues of nucleotides with a 1,2-alkadienic skeleton.

  Organic & biomolecular chemistry 20031207

• An unusual sugar conformation in the structure of an RNA/DNA decamer of the polypurine tract may affect recognition by RNase H.

  Journal of molecular biology 20031205

• Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter.

  American journal of physiology. Cell physiology 20031201

• Neuroprotective effect of adenine on purkinje cell survival in rat cerebellar primary cultures.

  Journal of neuroscience research 20031201

• Transfusion-associated GVHD after fludarabine therapy in a patient with systemic lupus erythematosus.

  Transfusion 20031201

• Nucleobase pairing in expanded Watson-Crick-like genetic information systems.

  Structure (London, England : 1993) 20031201

• The effect of a vegetarian and different omnivorous diets on urinary risk factors for uric acid stone formation.

  European journal of nutrition 20031201

• Catalysis by nucleoside hydrolases.

  Current opinion in structural biology 20031201

• Biological activity of inorganic arsenic and antimony reflects oxidation state in cultured human keratinocytes.

  Chemical research in toxicology 20031201

• Maintenance therapy for inflammatory bowel disease.

  The American journal of gastroenterology 20031201

• Peripheral T-cell lymphomas: diagnosis and management.

  Hematology/oncology clinics of North America 20031201

• Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.

  Nucleosides, nucleotides & nucleic acids 20031201

• Synthesis and antiviral activity of 2-substituted analogs of triciribine.

  Nucleosides, nucleotides & nucleic acids 20031201

• Synthesis and studies of 3'-C-trifluoromethyl-beta-D-ribonucleosides bearing the five naturally occurring nucleic acid bases.

  Nucleosides, nucleotides & nucleic acids 20031201

• Selective pressure on the allantoicase gene during vertebrate evolution.

  Journal of molecular evolution 20031201

• Modulation of Toll-like Receptor 9 Responses through Synthetic Immunostimulatory Motifs of DNA.

  Annals of the New York Academy of Sciences 20031201

• Clofarabine. Bioenvision/ILEX.

  Current opinion in investigational drugs (London, England : 2000) 20031201

• Variant Richter's syndrome: a rare case of classical Hodgkin's lymphoma developing in a patient with chronic lymphocytic leukemia treated with fludarabine.

  Leukemia & lymphoma 20031201

• Extension and cleavage of the polypurine tract plus-strand primer by Ty1 reverse transcriptase.

  The Journal of biological chemistry 20031128

• Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.

  The Journal of biological chemistry 20031121

• Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.

  Journal of medicinal chemistry 20031120

• Inhibition of caffeine biosynthesis in tea (Camellia sinensis) and coffee (Coffea arabica) plants by ribavirin.

  FEBS letters 20031120

• Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine?

  Journal of the American Chemical Society 20031119

• [Follicular lymphoma].

  Orvosi hetilap 20031116

• RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells.

  Cancer research 20031115

• Elongation of oligonucleotide primers forming a triple helix on double-stranded DNA templates by purified DNA polymerases.

  Biochemical and biophysical research communications 20031114

• The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal.

  Biochemical and biophysical research communications 20031114

• An unusual oxidative ring transformation of purine to imidazo[1,5-c]imidazole.

  Organic letters 20031113

• Eutectic phase polymerization of activated ribonucleotide mixtures yields quasi-equimolar incorporation of purine and pyrimidine nucleobases.

  Journal of the American Chemical Society 20031112

• Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.

  Biochemistry 20031111

• An approach to the generation of simple analogues of the antitumour agent spicamycin.

  Organic & biomolecular chemistry 20031107

• Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists.

  Journal of medicinal chemistry 20031106

• How strong can the bend be on a DNA helix from cisplatin? DFT and MP2 quantum chemical calculations of cisplatin-bridged DNA purine bases.

  Inorganic chemistry 20031103

• Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels.

  Neurochemistry international 20031101

• Interferon-gamma regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways.

  The Biochemical journal 20031101

• Genomic organization and functional characterization of the human concentrative nucleoside transporter-3 isoform (hCNT3) expressed in mammalian cells.

  Pflugers Archiv : European journal of physiology 20031101

• Functional evidence that ATP or a related purine is an inhibitory NANC neurotransmitter in the mouse jejunum: study on the identity of P2X and P2Y purinoceptors involved.

  British journal of pharmacology 20031101

• Acute adenosinergic cardioprotection in ischemic-reperfused hearts.

  American journal of physiology. Heart and circulatory physiology 20031101

• The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs.

  RNA (New York, N.Y.) 20031101

• Adenosine stimulation of the proliferation of colorectal carcinoma cell lines. Roles of cell density and adenosine metabolism.

  Biochemical pharmacology 20031101

• Antimycobacterial activity of 2-methyl-adenosine.

  The Journal of antimicrobial chemotherapy 20031101

• Favorable interactions between enfuvirtide and 1-beta-D-2,6-diaminopurine dioxolane in vitro.

  Antimicrobial agents and chemotherapy 20031101

• Capillary electrophoresis in diagnosis and monitoring of adenosine deaminase deficiency.

  Clinical chemistry 20031101

• The use of mycophenolate mofetil in liver transplant recipients.

  Expert opinion on pharmacotherapy 20031101

• Waldenström macroglobulinaemia.

  The Lancet. Oncology 20031101

• Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion.

  The British journal of ophthalmology 20031101

• Phase I clinical trial and pharmacokinetic study of the spicamycin analog KRN5500 administered as a 1-hour intravenous infusion for five consecutive days to patients with refractory solid tumors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20031101

• Purine and pyrimidine nucleotide metabolism in higher plants.

  Journal of plant physiology 20031101

• Synthesis and antiviral activity of novel trans-2,2-dimethyl cyclopropyl nucleosides.

  Archives of pharmacal research 20031101

• Emerging therapies for graft-versus-host disease.

  Expert opinion on emerging drugs 20031101

• Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin.

  Molecular and cellular neurosciences 20031101

• [Hairy-cell leukemia: 30 cases and a review of the literature].

  Annales de medecine interne 20031101

• Chemical composition of some components of the arrestment pheromone of the black-legged tick, Ixodes scapularis (Acari: Ixodidae) and their use in tick control.

  Journal of medical entomology 20031101

• Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines.

  Biochemistry 20031028

• Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures.

  The Journal of biological chemistry 20031024

• Inhibition of primary colon carcinoma growth and liver metastasis by the A3 adenosine receptor agonist CF101.

  British journal of cancer 20031020

• Mass spectrometric method for detecting carbon 13 enrichment introduced by folate coenzymes in uric acid.

  Analytical biochemistry 20031015

• Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA.

  The Journal of biological chemistry 20031010

• Structural basis for inhibition of human PNP by immucillin-H.

  Biochemical and biophysical research communications 20031003

• Docking and small angle X-ray scattering studies of purine nucleoside phosphorylase.

  Biochemical and biophysical research communications 20031003

• Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction.

  Organic letters 20031002

• Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway.

  American journal of physiology. Gastrointestinal and liver physiology 20031001

• Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells.

  Cancer chemotherapy and pharmacology 20031001

• Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia.

  Pflugers Archiv : European journal of physiology 20031001

• Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20031001

• The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum.

  PLoS biology 20031001

• Purine alkaloids in Paullinia.

  Phytochemistry 20031001

• Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases.

  The EMBO journal 20031001

• Granulomatous slack skin disease--disease features and response to pentostatin.

  British journal of haematology 20031001

• Nucleosome position-dependent and -independent activation of HIS7 epression in Saccharomyces cerevisiae by different transcriptional activators.

  Eukaryotic cell 20031001

• Better late than never for repair of miscoding lesions within a transcribed template.

  Molecular cell 20031001

• Aging-related changes in myocardial purine metabolism and ischemic tolerance.

  Experimental gerontology 20031001

• Thiosugars. X. Novel nucleoside analogues derived from 4-thio-L-lyxofuranose.

  Nucleosides, nucleotides & nucleic acids 20031001

• Drug transport and drug resistance in African trypanosomes.

  Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20031001

• Patterns of codon usage bias in three dicot and four monocot plant species.

  Genes & genetic systems 20031001

• Clonal expansion of adult rat hepatic stem cell lines by suppression of asymmetric cell kinetics (SACK).

  Biotechnology and bioengineering 20030930

• Cofactor determination and spectroscopic characterization of the selenium-dependent purine hydroxylase from Clostridium purinolyticum.

  Biochemistry 20030930

• An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress.

  The Journal of biological chemistry 20030926

• Cationic lipids and cationic ligands induce DNA helix denaturation: detection of single stranded regions by KMnO4 probing.

  FEBS letters 20030925

• DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).

  Journal of the American Chemical Society 20030924

• Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.

  Biochemistry 20030923

• Asymmetric synthesis of oxygen heterocycles via Pd-catalyzed dynamic kinetic asymmetric transformations: application to nucleosides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030922

• Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).

  The Biochemical journal 20030915

• Determination of phosphate in nanomolar range by an enzyme-coupling fluorescent method.

  Analytical biochemistry 20030915

• 2,6,8,9-tetrasubstituted purines as new CDK1 inhibitors.

  Bioorganic & medicinal chemistry letters 20030915

• Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases.

  Bioorganic & medicinal chemistry letters 20030915

• Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus.

  Virology 20030915

• Equilibrative nucleoside transporters of Arabidopsis thaliana. cDNA cloning, expression pattern, and analysis of transport activities.

  The Journal of biological chemistry 20030912

• Effects of purine nucleosides on the in vitro growth of Cryptosporidium parvum.

  FEMS microbiology letters 20030912

• Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase.

  Biochemistry 20030909

• Development of donor-acceptor modified DNA hairpins for the investigation of charge hopping kinetics in DNA.

  Chemical communications (Cambridge, England) 20030907

• A biochemical characterization of the adeno-associated virus Rep40 helicase.

  The Journal of biological chemistry 20030905

• ATP and ADP hydrolysis in brain membranes of zebrafish (Danio rerio).

  Life sciences 20030905

• Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II).

  Journal of the American Chemical Society 20030903

• Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II).

  Journal of the American Chemical Society 20030903

• Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product.

  Biochemistry 20030902

• Signalling from adenosine receptors to mitogen-activated protein kinases.

  Cellular signalling 20030901

• Glutamine and the maintenance of meiotic arrest in mouse oocytes: influence of culture medium, glucose, and cumulus cells.

  Molecular reproduction and development 20030901

• Low levels of endogenous oxidative damage cluster levels in unirradiated viral and human DNAs.

  Free radical biology & medicine 20030901

• Purine and pyrimidine metabolites in children's urine.

  Clinica chimica acta; international journal of clinical chemistry 20030901

• Cutaneous reactions in hairy cell leukaemia treated with 2-chlorodeoxyadenosine and allopurinol.

  British journal of haematology 20030901

• Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts.

  Circulation journal : official journal of the Japanese Circulation Society 20030901

• Role of urinary inhibitors of crystallization in uric acid nephrolithiasis: Dalmatian dog model.

  Urology 20030901

• Potential chemotherapeutic targets in the purine metabolism of parasites.

  Pharmacology & therapeutics 20030901

• Carbocyclic analogues of nucleosides from bis-(Hydroxymethyl)-cyclopentane: synthesis, antiviral and cytostatic activities of adenosine, inosine and uridine analogues.

  Chemical & pharmaceutical bulletin 20030901

• Uric acid stone disease.

  Frontiers in bioscience : a journal and virtual library 20030901

• [Cloning, expression and characterization of the hypoxanthine-guanine phosphoribosyltransferase mutants from T. tengcongensis].

  Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030901

• Lymphocyte DNA damage precedes DNA repair or cell death after orthopaedic surgery under general anaesthesia.

  Mutagenesis 20030901

• Antioxidant and prooxidant properties of caffeine, theobromine and xanthine.

  Medical science monitor : international medical journal of experimental and clinical research 20030901

• Influence of diet on growth yields of rumen micro-organisms in vitro and in vivo: influence on growth yield of variable carbon fluxes to fermentation products.

  The British journal of nutrition 20030901

• Platinum complexes of diaminocarboxylic acids and their ethyl ester derivatives: the effect of the chelate ring size on antitumor activity and interactions with GMP and DNA.

  Journal of inorganic biochemistry 20030901

• Nigral glutathione deficiency is not specific for idiopathic Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20030901

• [Non-myeloablative or reduced intensity stem cell transplantation preparative regimens].

  Nihon rinsho. Japanese journal of clinical medicine 20030901

• [Mini-transplantation for solid tumors].

  Nihon rinsho. Japanese journal of clinical medicine 20030901

• Excessive purine degradation during semi-ischemic forearm test in patients with diabetes mellitus.

  Internal medicine (Tokyo, Japan) 20030901

• Epidemic and nonepidemic multidrug-resistant Enterococcus faecium.

  Emerging infectious diseases 20030901

• [Urate transporter and renal hypouricemia].

  Rinsho byori. The Japanese journal of clinical pathology 20030901

• Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides.

  Archives of pharmacal research 20030901

• The influence of imatinib mesylate (STI571) used alone or in combination with purine nucleoside analogues on the normal and chronic myelogenous leukaemia progenitor cells in vitro.

  Leukemia & lymphoma 20030901

• Cardiac adaptation to endurance exercise in rats.

  Molecular and cellular biochemistry 20030901

• Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes.

  Molecular and biochemical parasitology 20030831

• Crystal structure of human purine nucleoside phosphorylase at 2.3A resolution.

  Biochemical and biophysical research communications 20030829

• Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir.

  Biochemical and biophysical research communications 20030829

• [The place of mycophenolate mofetil in glomerular diseases].

  Presse medicale (Paris, France : 1983) 20030823

• Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase.

  The Journal of biological chemistry 20030822

• Atoms-in-molecules study of the genetically encoded amino acids. III. Bond and atomic properties and their correlations with experiment including mutation-induced changes in protein stability and genetic coding.

  Proteins 20030815

• A consensus-binding structure for adenine at the atomic level permits searching for the ligand site in a wide spectrum of adenine-containing complexes.

  Proteins 20030815

• MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.

  The Journal of biological chemistry 20030808

• Selectivity of purine alkylation by a quinone methide. Kinetic or thermodynamic control?

  The Journal of organic chemistry 20030808

• [Avoid purine-rich foods, drink a lot, reduce weight. The most important recipes against hyperuricemia].

  MMW Fortschritte der Medizin 20030807

• Synthesis and properties of oligo-2'-deoxyribonucleotides containing internucleotidic phosphoramidate linkages modified with pendant groups ending with either two amino or two hydroxyl functions.

  Bioorganic & medicinal chemistry 20030805

• Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.

  Chembiochem : a European journal of chemical biology 20030804

• Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells.

  International journal of oncology 20030801

• Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.

  RNA (New York, N.Y.) 20030801

• Leflunomide treatment of Crohn's disease patients intolerant to standard immunomodulator therapy.

  Journal of clinical gastroenterology 20030801

• Purine and sugar chemistry on solid phase--100 years after the Emil Fischer's Chemistry Nobel Prize 1902.

  Combinatorial chemistry & high throughput screening 20030801

• Solvation of nucleosides in aqueous mixtures of organic solvents: relevance to DNA open basepairs.

  Biophysical journal 20030801

• Interaction centres of purine nucleotides: adenosine-5'-diphosphate and adenosine-5'-triphosphate in their reactions with tetramines and Cu(II) ions.

  Journal of inorganic biochemistry 20030801

• Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.

  Biochemical and biophysical research communications 20030801

• Oral choline decreases brain purine levels in lithium-treated subjects with rapid-cycling bipolar disorder: a double-blind trial using proton and lithium magnetic resonance spectroscopy.

  Bipolar disorders 20030801

• Disease activity and pretreatment, rather than hypogammaglobulinaemia, are major risk factors for infectious complications in patients with chronic lymphocytic leukaemia.

  British journal of haematology 20030801

• Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy.

  Biochemical pharmacology 20030801

• Carbohydrates digestibility and faecal nitrogen excretion in rats fed raw or germinated faba bean (Vicia faba)- and chickpea (Cicer arietinum)-based diets.

  The British journal of nutrition 20030801

• Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans.

  Environmental health perspectives 20030801

• Identification of trans-dominant modifiers of Prat expression in Drosophila melanogaster.

  Genetics 20030801

• Alemtuzumab therapy in B-cell lymphoproliferative disorders.

  Seminars in oncology 20030801

• Four cases of red blood cell aplasia in association with the use of mycophenolate mofetil in renal transplant patients.

  Clinical nephrology 20030801

• Nonmyeloablative transplantation for lymphoma.

  Current treatment options in oncology 20030801

• Early reappearance of primary solid cancer in patients treated with purine analogs.

  Journal of chemotherapy (Florence, Italy) 20030801

• A novel GT-mismatch binding protein that recognizes strict DNA sequences with high affinity.

  The Tohoku journal of experimental medicine 20030801

• [Inhibition of respiratory syncytial virus replication in cultured cells by RNA-cleaving DNAzyme].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20030801

• Adenosine extracellular levels in human brain gliomas: an intraoperative microdialysis study.

  Neuroscience letters 20030731

• Thyroid hormone upregulates ecto-5'-nucleotidase/CD73 in C6 rat glioma cells.

  Molecular and cellular endocrinology 20030731

• Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

  International journal for parasitology 20030730

• Synthesis of pyrene and benzo[a]pyrene adducts at the exocyclic amino groups of 2'-deoxyadenosine and 2'-deoxyguanosine by a palladium-mediated C-N bond-formation strategy.

  The Journal of organic chemistry 20030725

• Solution structure of a wedge-shaped synthetic molecule at a two-base bulge site in DNA.

  Biochemistry 20030722

• 1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues.

  Bioorganic & medicinal chemistry letters 20030721

• Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.

  Journal of medicinal chemistry 20030717

• 3-Bromopyrazolo[3,4-d]pyrimidine 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides: modified DNA constituents with an unusually rigid sugar N-conformation.

  The Journal of organic chemistry 20030711

• An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed cross-coupling reactions of 2,6-dichloropurines.

  The Journal of organic chemistry 20030711

• Sequence- and regioselectivity in the montmorillonite-catalyzed synthesis of RNA.

  Journal of the American Chemical Society 20030709

• Porin OmpP2 of Haemophilus influenzae shows specificity for nicotinamide-derived nucleotide substrates.

  The Journal of biological chemistry 20030704

• Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-5'-nucleotidase/CD73-dependent mechanism.

  The Journal of biological chemistry 20030704

• Identification of the antineoplastic agent 6-mercaptopurine as an activator of the orphan nuclear hormone receptor Nurr1.

  The Journal of biological chemistry 20030704

• DNA-protein cross-link formation mediated by oxanine. A novel genotoxic mechanism of nitric oxide-induced DNA damage.

  The Journal of biological chemistry 20030704

• Simultaneous determination of orthophosphate and total phosphates (inorganic phosphates plus purine nucleotides) using a bioamperometric flow-injection system made up by a 16-way switching valve.

  Talanta 20030704

• Characterisation of an uridine-specific binding site in rat cerebrocortical homogenates.

  Neurochemistry international 20030701

• Posttranslational inactivation of human xanthine oxidoreductase by oxygen under standard cell culture conditions.

  American journal of physiology. Cell physiology 20030701

• Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.

  Toxicological sciences : an official journal of the Society of Toxicology 20030701

• Variation between observed and true Terminal Restriction Fragment length is dependent on true TRF length and purine content.

  Journal of microbiological methods 20030701

• Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701

• Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture.

  Toxicological sciences : an official journal of the Society of Toxicology 20030701

• Fludarabine plus cyclophosphamide for the treatment of advanced chronic lymphocytic leukemia.

  European journal of haematology 20030701

• Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility.

  Endocrinology 20030701

• A single intravenous injection of KRN5500 (antibiotic spicamycin) produces long-term decreases in multiple sensory hypersensitivities in neuropathic pain.

  Anesthesia and analgesia 20030701

• Active site mutants of Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.

  European journal of biochemistry 20030701

• Interpretation of fluorescence decays using a power-like model.

  Biophysical journal 20030701

• The mosaic of immunosuppressive drugs.

  Molecular immunology 20030701

• Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia.

  Leukemia 20030701

• High complete response rate after allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning regimens in advanced malignant lymphoma.

  Bone marrow transplantation 20030701

• Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups.

  European journal of biochemistry 20030701

• Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman.

  Arthritis and rheumatism 20030701

• A purL mutant of Sinorhizobium fredii HH103 is symbiotically defective and altered in its lipopolysaccharide.

  Microbiology (Reading, England) 20030701

• Rituximab therapy for follicular lymphoma: a comprehensive review of its efficacy as primary treatment, treatment for relapsed disease, re-treatment and maintenance.

  Haematologica 20030701

• [Anti-inflammatory constituents, aloesin and aloemannan in Aloe species and effects of tanshinon VI in Salvia miltiorrhiza on heart].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030701

• Applications of triple-stranded nucleic acid structures to DNA purification, detection and analysis.

  Expert review of molecular diagnostics 20030701

• Biopharmaceutical characterization of some synthetic purine drugs.

  Die Pharmazie 20030701

• Electrochemical tagging of urate: developing new redox probes.

  The Analyst 20030701

• Reduced-intensity allogeneic stem cell transplantation.

  Current hematology reports 20030701

• Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies.

  Leukemia & lymphoma 20030701

• Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

  The Journal of biological chemistry 20030627

• Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis.

  Brain research 20030627

• Synthesis and antiviral evaluation of 2'-deoxy-2'-C-trifiuoromethyl beta-D-ribonucleoside analogues bearing the five naturally occurring nucleic acid bases.

  Organic & biomolecular chemistry 20030621

• A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients.

  Life sciences 20030620

• Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines.

  British journal of cancer 20030616

• 2,6-Diamino-5,8-diaza-7,9-dicarba-purine.

  Organic letters 20030612

• C-Nucleosidations with 2,6-diamino-5,8-diaza-7,9-dicarba-purine.

  Organic letters 20030612

• Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3.

  The Journal of biological chemistry 20030606

• One-pot TiO2-catalyzed synthesis of nucleic bases and acyclonucleosides from formamide: implications for the origin of life.

  Chembiochem : a European journal of chemical biology 20030606

• High-level activation by a duodenum-specific enhancer requires functional GATA binding sites.

  American journal of physiology. Gastrointestinal and liver physiology 20030601

• KRN5500: a novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis.

  Blood 20030601

• Theoretical ab initio study of the effects of methylation on structure and stability of G:C Watson-Crick base pair.

  Journal of biomolecular structure & dynamics 20030601

• Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site.

  European journal of biochemistry 20030601

• Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes.

  Journal of immunology (Baltimore, Md. : 1950) 20030601

• Expression of genes for certain enzymes of pyrimidine and purine salvage pathway in peripheral blood leukocytes collected from patients with Graves' or Hashimoto's disease.

  Journal of cellular biochemistry 20030601

• Toll-like receptor 9: modulation of recognition and cytokine induction by novel synthetic CpG DNAs.

  Biochemical Society transactions 20030601

• Cloning, expression and preliminary crystallographic studies of the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni.

  Acta crystallographica. Section D, Biological crystallography 20030601

• Mechanism of action of purine analogues in chronic lymphocytic leukaemia.

  British journal of haematology 20030601

• Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777.

  International immunopharmacology 20030601

• Homo- and heteroexchange of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system.

  British journal of pharmacology 20030601

• Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.

  Yeast (Chichester, England) 20030601

• Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030601

• Allantoin, the oxidation product of uric acid is present in chicken and turkey plasma.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030601

• New tricks for an old dogma: riboswitches as cis-only regulatory systems.

  Molecular cell 20030601

• Regulation of bone resorption and formation by purines and pyrimidines.

  Trends in pharmacological sciences 20030601

• Molecular characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase-deficient mutant clones of murine lymphoma cell line R1.1.

  Cancer science 20030601

• Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis.

  Cellular and molecular neurobiology 20030601

• Altering soluble and potentially rumen degradable protein for prepubertal Holstein heifers.

  Journal of dairy science 20030601

• Effects of a polymer-coated urea product on nitrogen metabolism in lactating Holstein dairy cattle.

  Journal of dairy science 20030601

• Effects of increasing dietary protein on nutrient utilization in heifers.

  Journal of dairy science 20030601

• Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.

  International journal of hematology 20030601

• Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea.

  AAPS pharmSci 20030601

• Phase I and pharmacokinetic study of KRN5500, a spicamycin derivative, for patients with advanced solid tumors.

  Japanese journal of clinical oncology 20030601

• Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.

  Cell 20030530

• Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.

  Biochemistry 20030527

• Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs.

  The Journal of biological chemistry 20030523

• Metal coordination-based inhibitors of adenylyl cyclase: novel potent P-site antagonists.

  Journal of medicinal chemistry 20030522

• Base sequence effects in radical cation migration in duplex DNA: support for the polaron-like hopping model.

  Journal of the American Chemical Society 20030521

• Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

  Biochemistry 20030520

• Differential control of cell cycle, proliferation, and survival of primary T lymphocytes by purine and pyrimidine nucleotides.

  Journal of immunology (Baltimore, Md. : 1950) 20030515

• Selective C-arylation of free (NH)-heteroarenes via catalytic C-H bond functionalization.

  Journal of the American Chemical Society 20030507

• Toward novel DNA binding metal complexes: structure and basic kinetic data of [M(9MeG)2(CH3OH)(CO)3]+(M = 99Tc, Re).

  Inorganic chemistry 20030505

• L-serine in disease and development.

  The Biochemical journal 20030501

• Development and application of bioprobes for Mammalian cell cycle analyses.

  Current medicinal chemistry 20030501

• P2X(2) purine receptor immunoreactivity of intraganglionic laminar endings in the mouse gastrointestinal tract.

  Cell and tissue research 20030501

• The role of context-dependent mutations in generating compositional and codon usage bias in grass chloroplast DNA.

  Journal of molecular evolution 20030501

• The PRAT purine synthesis gene duplication in Drosophila melanogaster and Drosophila virilis is associated with a retrotransposition event and diversification of expression patterns.

  Journal of molecular evolution 20030501

• Successful treatment of a patient with hairy cell leukemia and pentostatin-induced autoimmune thrombocytopenia with rituximab.

  American journal of hematology 20030501

• DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination.

  Investigative ophthalmology & visual science 20030501

• Effect of exercise and beer on the plasma concentration and urinary excretion of purine bases.

  The Journal of rheumatology 20030501

• Proteome analysis of the purine stimulon from Lactococcus lactis.

  Proteomics 20030501

• [Studies on the syntheses of the hypermodified nucleosides of phenylalanine transfer ribonucleic acids].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030501

• Synchrony of nutrient supply to the rumen and dietary energy source and their effects on the growth and metabolism of lambs.

  Journal of animal science 20030501

• Changes in ectonucleotidase activities in rat Sertoli cells during sexual maturation.

  Molecular and cellular biochemistry 20030501

• Translation Inhibition of Capped and Uncapped Viral RNAs Mediated by Ribosome-Inactivating Proteins.

  Phytopathology 20030501

• Clear distinction of purine bases on the complementary strand by a fluorescence change of a novel fluorescent nucleoside.

  Journal of the American Chemical Society 20030430

• Effects of inosine on axonal regeneration of axotomized retinal ganglion cells in adult rats.

  Neuroscience letters 20030424

• Review of a promising new agent--pemetrexed disodium.

  Cancer 20030415

• A substantial level of donor hematopoietic chimerism is required to protect donor-specific islet grafts in diabetic NOD mice.

  Transplantation 20030415

• The role of the minor groove substituents in indirect readout of DNA sequence by 434 repressor.

  The Journal of biological chemistry 20030411

• Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus.

  Journal of medicinal chemistry 20030410

• Gene expression patterns define pathways correlated with loss of differentiation in lung adenocarcinomas.

  FEBS letters 20030410

• Adenosine is the primary precursor of all purine nucleotides in Trichomonas vaginalis.

  Molecular and biochemical parasitology 20030403

• A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter.

  Molecular pharmacology 20030401

• Binding of fatty acids to the uncoupling protein from brown adipose tissue mitochondria.

  Archives of biochemistry and biophysics 20030401

• Role of MHC class I in immune surveillance of mitochondrial DNA integrity.

  Journal of immunology (Baltimore, Md. : 1950) 20030401

• Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation.

  Biochemistry 20030401

• Transport of cytokinins mediated by purine transporters of the PUP family expressed in phloem, hydathodes, and pollen of Arabidopsis.

  The Plant journal : for cell and molecular biology 20030401

• Uptake and release of [3H]adenosine in human dental pulp.

  Archives of oral biology 20030401

• Pentostatin and cyclophosphamide: an effective new regimen in previously treated patients with chronic lymphocytic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401

• Mixed ligand complexes of platinum(II) and palladium(II) with cytokinin-derived compounds Bohemine and Olomoucine: X-ray structure of [Pt(BohH+-N7)Cl(3)].9/5H2O [Boh=6-(benzylamino)-2-[(3-(hydroxypropyl)-amino]-9-isopropylpurine, Bohemine].

  Journal of inorganic biochemistry 20030401

• Nucleotides modulate the activity of aspartate racemase of Scapharca broughtonii.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030401

• Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2'-deoxyguanosine in primates.

  International immunopharmacology 20030401

• One-step purification of 5-enolpyruvylshikimate-3-phosphate synthase enzyme from Mycobacterium tuberculosis.

  Protein expression and purification 20030401

• Covalent binding of leukotriene A4 to DNA and RNA.

  Chemical research in toxicology 20030401

• Tubular injury: the first symptom of hypertensive kidney involvement?

  Medical science monitor : international medical journal of experimental and clinical research 20030401

• Adenosine 5'-triphosphate (ATP) is an excitatory cotransmitter with noradrenaline to the smooth muscle of the rat prostate gland.

  British journal of pharmacology 20030401

• Special sensitization pattern in adenosine-induced myocardial responses after thyroxine-treatment.

  Journal of pharmacological sciences 20030401

• Fludarabine in Waldenstrom's macroglobulinemia.

  Seminars in oncology 20030401

• Treatment of Waldenstrom's macroglobulinemia with clarithromycin, low-dose thalidomide, and dexamethasone.

  Seminars in oncology 20030401

• Role for high-dose therapy with autologous hematopoietic stem cell support in Waldenstrom's macroglobulinemia.

  Seminars in oncology 20030401

• Autologous and allogeneic stem cell transplantation in Waldenstrom's macroglobulinemia: review of the literature and future directions.

  Seminars in oncology 20030401

• Pemetrexed (Alimta): a novel multitargeted antifolate agent.

  Expert review of anticancer therapy 20030401

• Overview of non-Hodgkin's lymphoma: biology, staging, and treatment.

  Seminars in oncology 20030401

• Purine derivative excretion in dairy cows: endogenous excretion and the effect of exogenous nucleic acid supply.

  Journal of dairy science 20030401

• Effect of feeding protein supplements of differing degradability on omasal flow of microbial and undegraded protein.

  Journal of dairy science 20030401

• Effects of varying dietary protein and energy levels on the production of lactating dairy cows.

  Journal of dairy science 20030401

• [Enzymes of purine metabolism of lymphocytes and eosinophiles in bronchial asthma].

  Klinicheskaia laboratornaia diagnostika 20030401

• The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles.

  Cellular and molecular life sciences : CMLS 20030401

• Intraocular adenosine levels in normal and ocular-hypertensive patients.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030401

• Involvement of purinergic signaling in cardiovascular diseases.

  Drug news & perspectives 20030401

• Synthesis, structural studies, and biological evaluation of some purine substituted 1-aminocyclopropane-1-carboxylic acids and 1-amino-1-hydroxymethylcyclopropanes.

  Nucleosides, nucleotides & nucleic acids 20030401

• Mechanisms of release of ATP from vascular purinergic nerves.

  Autonomic & autacoid pharmacology 20030401

• DFT analysis of NMR scalar interactions across the glycosidic bond in DNA.

  Journal of the American Chemical Society 20030326

• 1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases.

  Bioorganic & medicinal chemistry letters 20030324

• Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase.

  Bioorganic & medicinal chemistry letters 20030324

• Polyethylene glycol-conjugated adenosine phosphorylase: development of alternative enzyme therapy for adenosine deaminase deficiency.

  Biochimica et biophysica acta 20030320

• Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates.

  Virology 20030315

• Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity.

  Journal of molecular biology 20030307

• Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis.

  Brain & development 20030301

• Novel antifolate drugs.

  Current oncology reports 20030301

• Purine and deazapurine nucleosides: synthetic approaches, molecular modelling and biological activity.

  Farmaco (Societa chimica italiana : 1989) 20030301

• 2-Chlorodeoxyadenosine therapy for disseminated Langerhans cell histiocytosis.

  Mayo Clinic proceedings 20030301

• The effect of lead ions on the energy metabolism of human erythrocytes in vitro.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030301

• Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation.

  Naunyn-Schmiedeberg's archives of pharmacology 20030301

• Enhanced adenosine A(2B) mediated coronary response in reserpinised rat heart.

  Naunyn-Schmiedeberg's archives of pharmacology 20030301

• [Colorectal cancer and folate].

  Zeitschrift fur Gastroenterologie 20030301

• Splenectomy and treatments of historical interest.

  Best practice & research. Clinical haematology 20030301

• Interferon in the treatment of hairy-cell leukemia.

  Best practice & research. Clinical haematology 20030301

• Pentostatin in the treatment of hairy-cell leukemia.

  Best practice & research. Clinical haematology 20030301

• Cladribine in the treatment of hairy-cell leukaemia.

  Best practice & research. Clinical haematology 20030301

• Immunobiological treatments of hairy-cell leukaemia.

  Best practice & research. Clinical haematology 20030301

• Purine nucleoside analogues in the treatment of myleoid leukemias.

  Leukemia & lymphoma 20030301

• Toxicity of nitrous oxide.

  Best practice & research. Clinical anaesthesiology 20030301

• Synthesis of (Z)-(2,3-bis-hydroxymethyl)methylenecyclopropane analogues of purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030301

• Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter.

  Journal of medicinal chemistry 20030227

• Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.

  Biochemistry 20030225

• Survival with dacarbazine and fotemustine in newly diagnosed glioblastoma multiforme.

  British journal of cancer 20030224

• Synthesis of purine- and pyrimidine-substituted heptadienes. The stereochemistry of cyclization and cyclopolymerization products.

  The Journal of organic chemistry 20030221

• Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells.

  Biochemical and biophysical research communications 20030214

• The transthyretin-related protein family.

  European journal of biochemistry 20030201

• 8'-aminoguanosine inclusion results in enhanced efflux of taurine in preconditioned ischemic myocardium.

  Journal of cardiovascular pharmacology 20030201

• Structure of bovine adenosine deaminase complexed with 6-hydroxy-1,6-dihydropurine riboside.

  Acta crystallographica. Section D, Biological crystallography 20030201

• Simultaneous determination of purine nucleotides, their metabolites and beta-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography.

  Brain research. Brain research protocols 20030201

• Advances in the treatment of hairy-cell leukaemia.

  The Lancet. Oncology 20030201

• Serum adenosine deaminase activity and its isoenzyme pattern in women with normal pregnancies.

  Archives of gynecology and obstetrics 20030201

• Enantioselective binding of S- and R-ofloxacin to various synthetic polynucleotides.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030201

• [Cladribine].

  Gan to kagaku ryoho. Cancer & chemotherapy 20030201

• Significance of the non-oxidative route of the pentose phosphate pathway for supplying carbon to the purine-nucleotide pathway in Corynebacterium ammoniagenes.

  Journal of industrial microbiology & biotechnology 20030201

• Sorting of rat SPNT in renal epithelium is independent of N-glycosylation.

  Pharmaceutical research 20030201

• Alkaline hydrolysis of cladribine.

  Die Pharmazie 20030201

• Diet and procedures used to detach particle-associated microbes from ruminal digesta influence chemical composition of microbes and estimation of microbial growth in Rusitec fermenters.

  Journal of animal science 20030201

• [Pathophysiology, diagnosis and conservative therapy of non-calcium kidney calculi].

  Therapeutische Umschau. Revue therapeutique 20030201

• Relation between reticulocyte count and characteristics of erythrocyte 5'-nucleotidase in dogs, cats, cattle and humans.

  The Journal of veterinary medical science 20030201

• Targeting bcl-2 by triplex-forming oligonucleotide--a promising carrier for gene-radiotherapy.

  Cancer biotherapy & radiopharmaceuticals 20030201

• Involvement of gibberellin and cytokinin in the formation of embryogenic cell clumps in carrot (Daucus carota).

  Journal of plant physiology 20030201

• Familial spastic paraplegia as the presenting manifestation in patients with purine nucleoside phosphorylase deficiency.

  Journal of child neurology 20030201

• [Prognostic significance of serum uric acid in patients with chronic obstructive pulmonary disease receiving home oxygen therapy].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20030201

• Synthesis and biological activities of 2-functionalized purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030201

• Synthesis of antisense oligonucleotides with minimum depurination.

  Nucleosides, nucleotides & nucleic acids 20030201

• A new method for the synthesis of 2'-O-benzyladenosine using Mitsunobu reaction.

  Nucleosides, nucleotides & nucleic acids 20030201

• A phase I clinical trial of spicamycin derivative KRN5500 (NSC 650426) using a phase I accelerated titration '2B' design.

  Investigational new drugs 20030201

• [Reversible temperature dependence of surface-enhanced Raman scattering of adenine, purine and pyrene].

  Guang pu xue yu guang pu fen xi = Guang pu 20030201

• Electrospray ionisation mass spectrometry: principles and clinical applications.

  The Clinical biochemist. Reviews 20030201

• Pressures in archaeal protein coding genes: a comparative study.

  Comparative and functional genomics 20030201

• Binding of the priming nucleotide in the initiation of transcription by T7 RNA polymerase.

  The Journal of biological chemistry 20030131

• Synthesis, anti-HIV activity, and molecular mechanism of drug resistance of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.

  Journal of medicinal chemistry 20030130

• Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead.

  Journal of medicinal chemistry 20030130

• Nucleic acid related compounds. 118. Nonaqueous diazotization of aminopurine derivatives. Convenient access to 6-halo- and 2,6-dihalopurine nucleosides and 2'-deoxynucleosides with acyl or silyl halides.

  The Journal of organic chemistry 20030124

• [Chronic lymphocytic leukemia: high time for a risk-adapted approach].

  Nederlands tijdschrift voor geneeskunde 20030118

• Adenosine A1 receptors regulate the response of the mouse circadian clock to light.

  Brain research 20030117

• Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism.

  Journal of controlled release : official journal of the Controlled Release Society 20030117

• Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii.

  The Biochemical journal 20030115

• Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.

  Biochemical pharmacology 20030115

• Cytotoxicity and mode of action of vanada- and niobatricarbadecaboranyl monohalide complexes in human HL-60 promyelocytic leukemia cells.

  Journal of inorganic biochemistry 20030115

• Copper(II) complexes with uridine, uridine 5'-monophosphate, spermidine, or spermine in aqueous solution.

  Journal of inorganic biochemistry 20030115

• Intrinsic acid-base properties of purine derivatives in aqueous solution and comparison of the acidifying effects of platinum(II) coordinated to N1 or N7: acidifying effects are reciprocal and the proton 'outruns' divalent metal ions.

  Inorganic chemistry 20030113

• Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma.

  British journal of cancer 20030113

• Storage and release of ATP from astrocytes in culture.

  The Journal of biological chemistry 20030110

• [Effect of morphine on expression of gene of enzymes related to purine nucleotide metabolism in c6 glioma].

  Zhonghua yi xue za zhi 20030110

• DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats.

  Biochemical and biophysical research communications 20030103

• 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.

  Journal of medicinal chemistry 20030102

• New N-n-propyl-substituted 3-aryl- and 3-cyclohexylpiperidines as partial agonists at the D4 dopamine receptor.

  Journal of medicinal chemistry 20030102

• Inosine reduces inflammation and improves survival in a murine model of colitis.

  American journal of physiology. Gastrointestinal and liver physiology 20030101

• A three-enzyme microelectrode sensor for detecting purine release from central nervous system.

  Biosensors & bioelectronics 20030101

• Triplex-forming oligonucleotides as modulators of gene expression.

  The international journal of biochemistry & cell biology 20030101

• Influence of p53 and p21(WAF1) expression on sensitivity of cancer cells to cladribine.

  Biochemical pharmacology 20030101

• The stm4066 gene product of Salmonella enterica serovar Typhimurium has aminoimidazole riboside (AIRs) kinase activity and allows AIRs to satisfy the thiamine requirement of pur mutant strains.

  Journal of bacteriology 20030101

• Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.

  Cancer gene therapy 20030101

• Three 2-aminopurine derivatives.

  Acta crystallographica. Section C, Crystal structure communications 20030101

• Cloning, overexpression, and purification of functional human purine nucleoside phosphorylase.

  Protein expression and purification 20030101

• Algorithms for computing parsimonious evolutionary scenarios for genome evolution, the last universal common ancestor and dominance of horizontal gene transfer in the evolution of prokaryotes.

  BMC evolutionary biology 20030101

• Application of pharmacokinetic/pharmacodynamic and stochastic modelling to 6-mercaptopurine micronucleus induction in mouse bone marrow erythrocytes.

  Journal of applied toxicology : JAT 20030101

• Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety.

  Pharmacological research 20030101

• Long-term outcome with pentostatin treatment in hairy cell leukemia patients. A French retrospective study of 238 patients.

  Leukemia 20030101

• Microarray analysis of orthologous genes: conservation of the translational machinery across species at the sequence and expression level.

  Genome biology 20030101

• Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis.

  Annals of clinical biochemistry 20030101

• Marginal zone-related neoplasms of splenic and nodal origin.

  Haematologica 20030101

• Sensitive and high-throughput analyses of purine metabolites by dynamic pH junction multiplexed capillary electrophoresis: a new tool for metabolomic studies.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030101

• Analysis of purinergic and cholinergic fast synaptic transmission to identified myenteric neurons.

  Neuroscience 20030101

• Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae.

  BMC molecular biology 20030101

• Mass spectrometric investigation of N-sulfonylated purine nucleic bases and nucleosides.

  Rapid communications in mass spectrometry : RCM 20030101

• Nonmyeloablative preparative regimens for allogeneic hematopoietic transplantation. Biology and current indications.

  Oncology (Williston Park, N.Y.) 20030101

• [Changes in blood hormone levels in gout and methods of their correction (an experimental and clinical study)].

  Klinicheskaia laboratornaia diagnostika 20030101

• Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer.

  Genome biology 20030101

• Fludarabine in combination with cyclophosphamide decreases incidence of GVHD and maintains effective graft-versus-leukemia effect after allogeneic stem cell transplantation in murine lymphocytic leukemia.

  Bone marrow transplantation 20030101

• [Management of hyperuricemia in occupational health: with reference to 'guidelines for the management of hyperuricemia and gout'].

  Sangyo eiseigaku zasshi = Journal of occupational health 20030101

• [Biosynthetic pathways for purine nucleotides and uric acid].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Phosphoribosylpyrophosphate(PRPP) synthetase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Amidophosphoribosyltransferase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [GAR synthetase . GAR transformylase . AIR synthetase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [FGAM synthetase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [AIR carboxylase . SAICAR synthetase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [The second half of de novo synthetic pathway of IMP and conversion of IMP to AMP].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [IMP dehydrogenase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [GMP synthetase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Hypoxanthine guanine phosphoribosyltransferase (HPRT)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Adenine phosphoribosyltransferase (APRT)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [5'-nucleotidase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Purine nucleoside phosphorylase (PNP)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [AMP deaminase (AMPD)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [GMP reductase].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Effect of foods on serum uric acid level].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Effect of ethanol on uric acid level].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Hyperuricemia--definition and classification].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Idiopathic hyperuricemia].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Diet therapy for management of hyperuricemia and gout].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Exercise therapy for hyperuricemia].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Hyperuricemia associated with inborn errors of purine metabolism: screening, enzymatic and genetic diagnosis].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [PRPP synthetase superactivity].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Non-drug substance (over intake of foods which are contained purine body, fat and fructose)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Alcohol-related tissue injury and hyperuricemia].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Animal models for abnormal purine metabolism].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• [Contents of purine bases in foods and alcoholic beverages].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• Expression and localization of estrogen receptor-alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradiol.

  Reproductive biology and endocrinology : RB&E 20030101

• Signaling and regulation of G protein-coupled receptors in airway smooth muscle.

  Respiratory research 20030101

• Monitoring of protein profiles for the optimization of recombinant fermentation processes using public domain databases.

  Electrophoresis 20030101

• 5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells.

  Neuroscience 20030101

• The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms.

  BMC evolutionary biology 20030101

• Correlation of serum levels of adenosine deaminase activity and its isoenzymes with disease activity in rheumatoid arthritis.

  Clinical and experimental rheumatology 20030101

• Cyclin-dependent kinase modulators studied at the NCI: pre-clinical and clinical studies.

  Current medicinal chemistry. Anti-cancer agents 20030101

• [Significance of TPMT activity and TGNs level detection for individualizing 6-mercaptopurine chemotherapy].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030101

• Therapeutic efficacy and safety of 6-mercaptopurine and azathioprine in patients with Crohn's disease.

  Reviews in gastroenterological disorders 20030101

• In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential.

  Leukemia & lymphoma 20030101

• The effect of cyclosporin A used alone and in combination with either 2-chlorodeoxyadenosine or fludarabine on normal and chronic myelogenous leukemia progenitors in vitro.

  Archivum immunologiae et therapiae experimentalis 20030101

• Measurement of peroxisomal enzyme activities in the liver of brown trout (Salmo trutta), using spectrophotometric methods.

  BMC biochemistry 20030101

• New directions in the diagnosis and treatment of chronic lymphocytic leukaemia.

  Drugs 20030101

• Analysis and functional classification of transcripts from the nematode Meloidogyne incognita.

  Genome biology 20030101

• [The role of enzymatic features of hypoxia in ulcers].

  Likars'ka sprava 20030101

• Wavelet to predict bacterial ori and ter: a tendency towards a physical balance.

  BMC genomics 20030101

• The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase.

  BMC biochemistry 20030101

• Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents.

  Journal of molecular microbiology and biotechnology 20030101

• Potent P2Y6 receptor mediated contractions in human cerebral arteries.

  BMC pharmacology 20030101

• Solid-phase synthesis of nucleoside analogues.

  Journal of combinatorial chemistry 20030101

• Genome wide identification of regulatory motifs in Bacillus subtilis.

  BMC bioinformatics 20030101

• Nucleosides and nucleotides. 218. Alternate-strand triple-helix formation by the 3'-3'-linked oligodeoxynucleotides using a purine motif.

  Bioconjugate chemistry 20030101

• On heteroaromaticity of nucleobases. Bond lengths as multidimensional phenomena.

  Journal of chemical information and computer sciences 20030101

• Rapid de-localization of actin leading edge components with BDM treatment.

  BMC cell biology 20030101

• A national survey on the patterns of treatment of inflammatory bowel disease in Canada.

  BMC gastroenterology 20030101

• Model building and model checking for biochemical processes.

  Cell biochemistry and biophysics 20030101

• Horizontally transferred genes in plant-parasitic nematodes: a high-throughput genomic approach.

  Genome biology 20030101

• Characterisation of methionine adenosyltransferase from Mycobacterium smegmatis and M. tuberculosis.

  BMC microbiology 20030101

• Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements.

  Journal of biology 20030101

• Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine.

  Current eye research 20030101

• Internal correspondence analysis of codon and amino-acid usage in thermophilic bacteria.

  Journal of applied genetics 20030101

• Relationships between hemodynamic parameters and myocardial energy and antioxidant status in heart transplantation.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20030101

• Wegener's granulomatosis: current and upcoming therapies.

  Arthritis research & therapy 20030101

• Highly efficient lentiviral gene transfer in CD34+ and CD34+/38-/lin- cells from mobilized peripheral blood after cytokine prestimulation.

  Stem cells (Dayton, Ohio) 20030101

• Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.

  Molecular medicine (Cambridge, Mass.) 20030101

• Management of advanced chronic lymphocytic leukemia.

  Current hematology reports 20030101

• Comparative genomics of Archaea: how much have we learned in six years, and what's next?

  Genome biology 20030101

• [Arterial hypertension, its metabolic aspects and kidney function in patients after hemorrhagic fever with renal syndrome].

  Terapevticheskii arkhiv 20030101

• Exploring the molecular basis of selectivity in A1 adenosine receptors agonists: a case study.

  Journal of computer-aided molecular design 20030101

• The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences.

  Neuroscience 20030101

• Antioxidant intake, plasma antioxidants and oxidative stress in a randomized, controlled, parallel, Mediterranean dietary intervention study on patients with rheumatoid arthritis.

  Nutrition journal 20030101

• Pharmacokinetics and degree of aromatization rather than total dose of different preparations determine the effects of testosterone: a nonhuman primate study in Macaca fascicularis.

  Journal of andrology 20030101

• Increased retention of functional fusions to toxic genes in new two-hybrid libraries of the E. coli strain MG1655 and B. subtilis strain 168 genomes, prepared without passaging through E. coli.

  BMC genomics 20030101

• Conjugates of PNA with naphthalene diimide derivatives having a broad range of DNA affinities.

  Bioconjugate chemistry 20030101

• Relationship of SARS-CoV to other pathogenic RNA viruses explored by tetranucleotide usage profiling.

  BMC bioinformatics 20030101

• Synthesis of apio analogues of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase.

  Nucleic acids research. Supplement (2001) 20030101

• The NMR studies of substituent effects on the N-H...N hydrogen bond in duplex DNA using 2'-deoxynebularine and 15N labeled 5-substituted-2'-deoxyuridine base pairs.

  Nucleic acids research. Supplement (2001) 20030101

• Synthesis and biological properties of stable phosmidosine analogs.

  Nucleic acids research. Supplement (2001) 20030101

• Transition state analogues for enzymes of nucleic acid metabolism.

  Nucleic acids research. Supplement (2001) 20030101

• Thermodynamic analyses of purine motif triplex DNA formation.

  Nucleic acids research. Supplement (2001) 20030101

• Utilization efficiency of the oxidized purine nucleotide analogs by DNA polymerase eta.

  Nucleic acids research. Supplement (2001) 20030101

• Influence of glucose in dialyzing fluid on purine concentrations in hemodialyzed patients with chronic renal failure.

  Nephron. Clinical practice 20030101

• Oral fludarabine.

  Drugs 20030101

• Strategies in the design of prodrugs of anti-HIV agents.

  Current topics in medicinal chemistry 20030101

• Anticancer antifolates: current status and future directions.

  Current pharmaceutical design 20030101

• Thioguanine, mercaptopurine: their analogs and nucleosides as antimetabolites.

  Current pharmaceutical design 20030101

• Trustworthiness and metrics in visualizing similarity of gene expression.

  BMC bioinformatics 20030101

• An industrial process for synthesizing Lodenosine (FddA).

  Nucleosides, nucleotides & nucleic acids 20030101

• 4'-C-methyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides revisited.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthetic studies on guanofosfocin: glycosylation of 8-oxo-purine nucleosides via Mitsunobu reaction.

  Nucleosides, nucleotides & nucleic acids 20030101

• Selective metalation of 6-methylpurines: synthesis of 6-fluoromethylpurines and related nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030101

• Chemo-enzymatic synthesis of 3-deoxy-beta-D-ribofuranosyl purines and study of their biological properties.

  Nucleosides, nucleotides & nucleic acids 20030101

• Introduction of a benzyl group onto the 2'-OH of 6-chloropurine 3'-O-benzoylriboside.

  Nucleosides, nucleotides & nucleic acids 20030101

• Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis of 4'-C-ethynyl and 4'-C-cyano purine nucleosides from natural nucleosides and their anti-HIV activity.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis of modified RNA-oligonucleotides for structural investigations.

  Nucleosides, nucleotides & nucleic acids 20030101

• Oligonucleotides incorporating N7-(2'-deoxy-beta-D-erythro-pentofuranosyl)isoguanine.

  Nucleosides, nucleotides & nucleic acids 20030101

• 5'-O-fluorosulfonylbenzoyl esters of purine nucleosides as potential inhibitors of NTPase/helicase and polymerase of Flaviviridae viruses.

  Nucleosides, nucleotides & nucleic acids 20030101

• Recognition of cyclonucleoside lesions by the Lactococcus lactis FPG protein.

  Nucleosides, nucleotides & nucleic acids 20030101

• Interactions of potent multisubstrate analogue inhibitors with purine nucleoside phosphorylase from calf spleen--kinetic and spectrofluorimetric studies.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis and antitumor activity of N-sulfonyl derivatives of nucleobases and sulfonamido nucleoside derivatives.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis of 2-deoxy-beta-D-ribose 1-phosphate, NMR comparison and its enzymatic activity for structural elucidation of synthetic alpha-isomer.

  Nucleosides, nucleotides & nucleic acids 20030101

• Interactions of trimeric purine nucleoside phosphorylases with ground state analogues--calorimetric and fluorimetric studies.

  Nucleosides, nucleotides & nucleic acids 20030101

• Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone.

  Nucleosides, nucleotides & nucleic acids 20030101

• [Activity of purine enzyme metabolism in rat thymocytes after irradiation and after administration of riboxine].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

• Molecular characterization of the zebrafish P2X receptor subunit gene family.

  Neuroscience 20030101

• In vitro studies on DNA-photosensitization by different drug stereoisomers.

  Toxicology in vitro : an international journal published in association with BIBRA 20030101

• Multi-level response of the yeast genome to glucose.

  Genome biology 20030101

• [Diet therapy in combined disorders of purine and lipid metabolism in children].

  Voprosy pitaniia 20030101

• Hydrolytic cleavage of purine ribonucleosides in Aspergillus phoenicis.

  Journal of basic microbiology 20030101

• Infections in patients with hematological cancer: recent developments.

  Hematology. American Society of Hematology. Education Program 20030101

• Azathioprine as a treatment for severe atopic eczema in children with a partial thiopurine methyl transferase (TPMT) deficiency.

  Pediatric dermatology 20030101

• Systemic chemotherapy for the treatment of mycosis fungoides and Sézary syndrome.

  Dermatologic therapy 20030101

• Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice.

  BMC microbiology 20030101

• The tyranny of adenosine recognition among RNA aptamers to coenzyme A.

  BMC evolutionary biology 20030101

• Current data with pemetrexed (Alimta) in non-small-cell lung cancer.

  Clinical lung cancer 20030101

• Guanosine deaminase in human serum and tissue extracts--a reappraisal of the products.

  British journal of biomedical science 20030101

• Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis.

  Acta neurochirurgica. Supplement 20030101

• Plasticity of purine release during cerebral ischemia: clinical implications?

  Journal of cellular and molecular medicine 20030101

• Cellular issues relating to the resistance of HIV to antiretroviral agents.

  Scandinavian journal of infectious diseases. Supplementum 20030101

• Short pyrimidine stretches containing mixed base PNAs are versatile tools to induce translation elongation arrest and truncated protein synthesis.

  Oligonucleotides 20030101

• Cloning, expression, activity and folding studies of serine hydroxymethyltransferase: a target enzyme for cancer chemotherapy.

  Journal of molecular microbiology and biotechnology 20030101

• Cardiovascular drugs and serum uric acid.

  Cardiovascular drugs and therapy 20030101

• Comparison of responses by bacteriophages and bacteria to pressures on the base composition of open reading frames.

  Applied bioinformatics 20030101

• Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease.

  Advances in experimental medicine and biology 20030101

• [The influence of some trace elements on bioaccumulation in tissues and bioenergetic metabolism of the edible snail Helix aspersa maxima as determined by HPLC of purine derivatives].

  Annales Academiae Medicae Stetinensis 20030101

• New approaches to the treatment of overactive bladder: the purine pathways and an update on the tension-free vaginal tape sling.

  Reviews in urology 20030101

• Treatment of cutaneous T-cell lymphomas with purine analogues (fludarabine and 2-chlorodeoxyadenosine).

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20030101

• Structural insights into the avian AICAR transformylase mechanism.

  Biochemistry 20021231

• 2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplex.

  The Journal of biological chemistry 20021220

• Molecular recognition in purine-rich internal loops: thermodynamic, structural, and dynamic consequences of purine for adenine substitutions in 5'(rGGCAAGCCU)2.

  Biochemistry 20021217

• The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland.

  Genes & development 20021215

• A potent and highly selective sulfotransferase inhibitor.

  Journal of the American Chemical Society 20021211

• Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.

  Biochemistry 20021210

• Diagnosis and monitoring of inborn errors of metabolism using urease-pretreatment of urine, isotope dilution, and gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021205

• The diagnosis and treatment of hairy-cell leukaemia.

  Blood reviews 20021201

• Purine enzymes in patients with rheumatoid arthritis treated with methotrexate.

  Annals of the rheumatic diseases 20021201

• Discovery of novel targets of quinoline drugs in the human purine binding proteome.

  Molecular pharmacology 20021201

• Adduction of catechol estrogens to nucleosides.

  Steroids 20021201

• Functional regulation of xanthine oxidoreductase expression and localization in the mouse mammary gland: evidence of a role in lipid secretion.

  The Journal of physiology 20021201

• Induction of COX-2 and reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signalling.

  Journal of neurochemistry 20021201

• Atmospheric pressure ionization mass spectrometry of purine and pyrimidine markers of inherited metabolic disorders.

  Journal of mass spectrometry : JMS 20021201

• Sequence-dependent dynamics of duplex DNA: the applicability of a dinucleotide model.

  Biophysical journal 20021201

• Cardiac surgery: myocardial energy balance, antioxidant status and endothelial function after ischemia-reperfusion.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021201

• The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase.

  Biological chemistry 20021201

• Molecular, biochemical, and cellular pharmacology of pemetrexed.

  Seminars in oncology 20021201

• Are activation markers (CD25, CD38 and CD103) predictive of sensitivity to purine analogues in patients with T-cell prolymphocytic leukemia and other lymphoproliferative disorders?

  Leukemia & lymphoma 20021201

• Regulation of expression of the Rhizopus oryzae uricase and urease enzymes.

  Canadian journal of microbiology 20021201

• Modeling the transmembrane arrangement of the uncoupling protein UCP1 and topological considerations of the nucleotide-binding site.

  Journal of bioenergetics and biomembranes 20021201

• The trapping of a spontaneously 'flipped-out' base from double helical nucleic acids by host-guest complexation with beta-cyclodextrin: the intrinsic base-flipping rate constant for DNA and RNA.

  Journal of the American Chemical Society 20021127

• Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics.

  Biochimica et biophysica acta 20021119

• Concentrative nucleoside transporter (rCNT1) is targeted to the apical membrane through the hepatic transcytotic pathway.

  Experimental cell research 20021115

• Intrinsic lifetimes of the excited state of DNA and RNA bases.

  Journal of the American Chemical Society 20021106

• DNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects.

  Biopolymers 20021105

• Specific, sensitive and accurate liquid chromatographic-tandem mass spectrometric method for the measurement of ribavirin in rat and monkey plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021105

• 2-Aminopurine electronic structure and fluorescence properties in DNA.

  Biochemistry 20021105

• Hydroxamate based inhibitors of adenylyl cyclase. Part 1: the effect of acyclic linkers on P-site binding.

  Bioorganic & medicinal chemistry letters 20021104

• Hydroxamate based inhibitors of adenylyl cyclase. Part 2: the effect of cyclic linkers on P-site binding.

  Bioorganic & medicinal chemistry letters 20021104

• Cladribine induces immunophenotypical changes in bone marrow mast cells from mastocytosis. Report of a case of mastocytosis associated with a lymphoplasmacytic lymphoma.

  Leukemia research 20021101

• The activities of serum adenosine deaminase and xanthine oxidase enzymes in Behcet's disease.

  Clinica chimica acta; international journal of clinical chemistry 20021101

• Purine nucleoside phosphorylase: a fortuitous cytosolic arsenate reductase?

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Reduction of arsenate to arsenite in hepatic cytosol.

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Purine nucleoside phosphorylase as a cytosolic arsenate reductase.

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Determination of platinated purines in oligoribonucleotides by limited digestion with ribonucleases T1 and U2.

  Analytical biochemistry 20021101

• Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up.

  Carcinogenesis 20021101

• Comparison of peptides in the phloem sap of flowering and non-flowering Perilla and lupine plants using microbore HPLC followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Planta 20021101

• [Treatment of Lesch-Nyhan syndrome].

  Revista de neurologia 20021101

• Inhibitors of de novo nucleotide biosynthesis as drugs.

  Accounts of chemical research 20021101

• Proteomic evaluation of intermediary metabolism enzyme proteins in fetal Down's syndrome cerebral cortex.

  Proteomics 20021101

• Inosine modulates gut barrier dysfunction and end organ damage in a model of ischemia-reperfusion injury.

  The Journal of surgical research 20021101

• High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomas.

  Journal of cancer research and clinical oncology 20021101

• Incorporation of the anticancer agent KRN5500 into polymeric micelles diminishes the pulmonary toxicity.

  Japanese journal of cancer research : Gann 20021101

• The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system.

  Autonomic neuroscience : basic & clinical 20021031

• Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase.

  The Journal of biological chemistry 20021025

• Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.

  Journal of medicinal chemistry 20021024

• Reaction mechanism of the HGXPRTase from Plasmodium falciparum: a hybrid potential quantum mechanical/molecular mechanical study.

  Journal of the American Chemical Society 20021023

• [Uncommon purine lithiasis: adenine phosphoribosyltransferase (APRT) deficiency and hereditary xanthinuria].

  Medicina clinica 20021019

• The adenine phosphoribosyltransferase from Giardia lamblia has a unique reaction mechanism and unusual substrate binding properties.

  The Journal of biological chemistry 20021018

• Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains.

  Journal of immunology (Baltimore, Md. : 1950) 20021015

• A colorimetric 96-well microtiter plate assay for the determination of urate oxidase activity and its kinetic parameters.

  Analytical biochemistry 20021015

• The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site.

  Biochemistry 20021008

• Simultaneous expression of hCNT1-CFP and hENT1-YFP in Madin-Darby canine kidney cells. Localization and vectorial transport studies.

  The Journal of biological chemistry 20021004

• Mutations in the pho2 (bas2) transcription factor that differentially affect activation with its partner proteins bas1, pho4, and swi5.

  The Journal of biological chemistry 20021004

• Ring-expanded ('Fat') nucleosides as broad-spectrum anticancer and antiviral agents.

  Current topics in medicinal chemistry 20021001

• Simple non-radiochemical HPLC-linked method for screening for purine metabolism disorders using dried blood spot.

  Clinica chimica acta; international journal of clinical chemistry 20021001

• Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors.

  The Journal of pharmacology and experimental therapeutics 20021001

• Dynamics and binding modes of free cdk2 and its two complexes with inhibitors studied by computer simulations.

  Journal of biomolecular structure & dynamics 20021001

• Transfusion-associated graft-versus-host disease in a patient with Waldenstrom's macroglobulinaemia.

  Vox sanguinis 20021001

• Effect of beer on the plasma concentrations of uridine and purine bases.

  Metabolism: clinical and experimental 20021001

• Genome-wide identification of nodule-specific transcripts in the model legume Medicago truncatula.

  Plant physiology 20021001

• Development of a melanoma-specific adenovirus.

  Molecular therapy : the journal of the American Society of Gene Therapy 20021001

• Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions.

  Neuropharmacology 20021001

• Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

  Human genetics 20021001

• Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001

• Sequencing of 16S rRNA gene: a rapid tool for identification of Bacillus anthracis.

  Emerging infectious diseases 20021001

• PSF and p54nrb bind a conserved stem in U5 snRNA.

  RNA (New York, N.Y.) 20021001

• Chiral discrimination in platinum anticancer drugs.

  Environmental health perspectives 20021001

• Advances in gene therapy for ADA-deficient SCID.

  Current opinion in molecular therapeutics 20021001

• Purine nucleoside phosphorylase deficiency: a new case report and identification of two novel mutations (Gly156A1a and Val217Ile), only one of which (Gly156A1a) is deleterious.

  Clinical immunology (Orlando, Fla.) 20021001

• Plasma 5'-nucleotidase activities increase in women with hyperemesis gravidarum.

  Clinical biochemistry 20021001

• Synthesis and photophysics of purine-capped Q-CdS nanocrystallites.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021001

• The identification of five genetic loci of Francisella novicida associated with intracellular growth.

  FEMS microbiology letters 20020924

• A parity code interpretation of nucleotide alphabet composition.

  Chemical communications (Cambridge, England) 20020921

• An efficient and large-scale enantioselective synthesis of PNP405: a purine nucleoside phosphorylase inhibitor.

  The Journal of organic chemistry 20020920

• Nucleic acid related compounds. 116. Nonaqueous diazotization of aminopurine nucleosides. Mechanistic considerations and efficient procedures with tert-butyl nitrite or sodium nitrite.

  The Journal of organic chemistry 20020920

• A new concept for the preparation of beta-L- and beta-D-2',3'-dideoxynucleoside analogues.

  Organic letters 20020919

• Structure and function of xanthine oxidoreductase: where are we now?

  Free radical biology & medicine 20020915

• Antifolates targeting purine synthesis allow entry of tumor cells into S phase regardless of p53 function.

  Cancer research 20020915

• A water-soluble synthetic spicamycin derivative (San-Gly) decreases mechanical allodynia in a rodent model of neuropathic pain.

  Neuroscience letters 20020913

• Purine and pyrimidine (P2) receptors as drug targets.

  Journal of medicinal chemistry 20020912

• Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.

  Journal of medicinal chemistry 20020912

• Three-bond sugar-base couplings in purine versus pyrimidine nucleosides: a DFT study of Karplus relationships for (3)J(C2/4-H1') and (3)J(C6/8-H1') in DNA.

  Journal of the American Chemical Society 20020911

• Oxidative DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).

  Bioorganic & medicinal chemistry letters 20020902

• Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies.

  The Biochemical journal 20020901

• Adenine and deazaadenine nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1.

  Bioorganic & medicinal chemistry 20020901

• Peripheral T-cell lymphoma.

  Current oncology reports 20020901

• Waldenström's macroglobulinaemia.

  Blood reviews 20020901

• Pronounced cytostatic activity and bystander effect of a novel series of fluorescent tricyclic acyclovir and ganciclovir derivatives in herpes simplex virus thymidine kinase gene-transduced tumor cell lines.

  Gene therapy 20020901

• Recent advances in cyclin-dependent kinase inhibition. Purine-based derivatives as anti-cancer agents. Roles and perspectives for the future.

  Current topics in medicinal chemistry 20020901

• The contractile potency of adenosine triphosphate and ecto-adenosine triphosphatase activity in guinea pig detrusor and detrusor from patients with a stable, unstable or obstructed bladder.

  The Journal of urology 20020901

• Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.

  Hepatology (Baltimore, Md.) 20020901

• Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL).

  Leukemia 20020901

• Progress toward virtual screening for drug side effects.

  Proteins 20020901

• Toward a description of the sialome of the adult female mosquito Aedes aegypti.

  Insect biochemistry and molecular biology 20020901

• Cytotoxic effect of cyclosporin A alone and in combination with 2-chlorodeoxyadenosine against P388 murine leukemia in vivo.

  Medical science monitor : international medical journal of experimental and clinical research 20020901

• Frequent occurrence of the T-loop RNA folding motif in ribosomal RNAs.

  RNA (New York, N.Y.) 20020901

• Nucleosides are efficiently absorbed by Na(+)-dependent transport across the intestinal brush border membrane in veal calves.

  Journal of dairy science 20020901

• Eosinophilic pneumonia after administration of fludarabine for the treatment of non-Hodgkin's lymphoma.

  Annals of hematology 20020901

• [Purine regulon of gamma-proteobacteria: a detailed description].

  Genetika 20020901

• Photoionization of DNA and RNA bases, nucleosides and nucleotides through a combination of one- and two-photon pathways upon 266 nm nanosecond laser excitation.

  Photochemistry and photobiology 20020901

• Non-Hodgkin's lymphoma: the evolving role of purine analogues.

  Best practice & research. Clinical haematology 20020901

• Differentiation of human myeloid leukemia cells by plant redifferentiation-inducing hormones.

  Leukemia & lymphoma 20020901

• Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia.

  Leukemia & lymphoma 20020901

• The cryptic adenine deaminase gene of Escherichia coli. Silencing by the nucleoid-associated DNA-binding protein, H-NS, and activation by insertion elements.

  The Journal of biological chemistry 20020830

• Phosphorylation of pyrimidine L-deoxynucleoside analog diphosphates. Kinetics of phosphorylation and dephosphorylation of nucleoside analog diphosphates and triphosphates by 3-phosphoglycerate kinase.

  The Journal of biological chemistry 20020830

• Long-patch base excision repair of apurinic/apyrimidinic site DNA is decreased in mouse embryonic fibroblast cell lines treated with plumbagin: involvement of cyclin-dependent kinase inhibitor p21Waf-1/Cip-1.

  Oncogene 20020829

• Evaluation of rat liver apoptotic and necrotic cell death after cold storage using UW, HTK, and Celsior.

  Transplantation 20020827

• Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. Characterization of an unusual acetal byproduct.

  The Journal of organic chemistry 20020823

• The purine nucleoside phosphorylase from Trichomonas vaginalis is a homologue of the bacterial enzyme.

  Biochemistry 20020820

• Thermodynamic parameters for an expanded nearest-neighbor model for the formation of RNA duplexes with single nucleotide bulges.

  Biochemistry 20020820

• Misalignment-mediated DNA polymerase beta mutations: comparison of microsatellite and frame-shift error rates using a forward mutation assay.

  Biochemistry 20020820

• Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients.

  The Biochemical journal 20020815

• Distinct interactions of G(salpha-long), G(salpha-short), and G(alphaolf) with GTP, ITP, and XTP.

  Biochemical pharmacology 20020815

• Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.

  Chemico-biological interactions 20020815

• Perspectives on analyses of nucleic acid constituents: the basis of genomics.

  Journal of chromatography. A 20020802

• Is the anomeric effect an important factor in the rate of adenosine deaminase catalyzed hydrolysis of purine nucleosides? A direct comparison of nucleoside analogues constructed on ribose and carbocyclic templates with equivalent heterocyclic bases selected to promote hydration.

  Bioorganic & medicinal chemistry 20020801

• 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.

  Bioorganic & medicinal chemistry 20020801

• Atypical 5' splice sites cause CFTR exon 9 to be vulnerable to skipping.

  American journal of human genetics 20020801

• Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.

  American journal of physiology. Renal physiology 20020801

• Differential changes in purine nucleotides after Doxorubicin treatment of human cancer cells in vitro.

  International journal of oncology 20020801

• The necessity of combining genomic and enzymatic data to infer metabolic function and pathways in the smallest bacteria: amino acid, purine and pyrimidine metabolism in Mollicutes.

  Frontiers in bioscience : a journal and virtual library 20020801

• Molecular dynamics simulation study of DNA triplex formed by mixed sequences in solution.

  Journal of biomolecular structure & dynamics 20020801

• Anti-angiogenic activity of the purine analog 6-thioguanine.

  Leukemia 20020801

• Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines.

  Molecular pathology : MP 20020801

• Molybdoenzymes and molybdenum cofactor in plants.

  Journal of experimental botany 20020801

• Corticosteroid responsive fludarabine pulmonary toxicity.

  American journal of clinical oncology 20020801

• Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy.

  European journal of biochemistry 20020801

• Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.

  Cancer research 20020801

• Metabolism and mechanisms of action of bendamustine: rationales for combination therapies.

  Seminars in oncology 20020801

• Bendamustine in the treatment of chronic lymphocytic leukemia: results and future perspectives.

  Seminars in oncology 20020801

• Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery: a randomized controlled trial.

  The Annals of thoracic surgery 20020801

• On-line fourier transform infrared detection in capillary electrophoresis.

  Analytical chemistry 20020801

• Permeability of Coxiella burnetii to ribonucleosides.

  Microbiology (Reading, England) 20020801

• Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems.

  European journal of biochemistry 20020801

• Ferritin and desferrioxamine attenuate xanthine oxidase-dependent leak in isolated perfused rat lungs.

  Inflammation 20020801

• Normal transcription of the C1 inhibitor gene is dependent upon a polypurine-polypyrimidine region within the promoter.

  Inflammation 20020801

• Substrate recognition by a family of uracil-DNA glycosylases: UNG, MUG, and TDG.

  Chemical research in toxicology 20020801

• Pericardial concentrations of adenosine, inosine and hypoxanthine in an experimental canine model of spastic ischaemia.

  Clinical science (London, England : 1979) 20020801

• Endothelin-1-induced elevations in purine metabolite concentrations -- autoregulatory protection in the canine pericardium?

  Clinical science (London, England : 1979) 20020801

• Influence of moderate drinking on purine and carbohydrate metabolism.

  Alcoholism, clinical and experimental research 20020801

• Sulfinosine-induced cell growth inhibition and apoptosis in human lung carcinomas in vitro.

  Investigational new drugs 20020801

• Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

  Chemistry & biology 20020801

• Effects of forage particle size and grain fermentability in midlactation cows. I. Milk production and diet digestibility.

  Journal of dairy science 20020801

• Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.

  Molecular and cellular biochemistry 20020801

• Screening for adenylosuccinate lyase deficiency: clinical, biochemical and molecular findings in four patients.

  Neuropediatrics 20020801

• Purine metabolizing capability of Enterobacter agglomerans affects volatiles production and attractiveness to Mexican fruit fly.

  Journal of chemical ecology 20020801

• Waldenström's macroglobulinemia: a review of therapy.

  Leukemia & lymphoma 20020801

• Montmorillonite catalysis of 30-50 mer oligonucleotides: laboratory demonstration of potential steps in the origin of the RNA world.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020801

• Purine metabolism in leukocytes and erythrocytes in Graves' or Hashimoto's disease.

  Endocrine research 20020801

• Studies on the thermal decomposition process and kinetics of purine drugs.

  Yao xue xue bao = Acta pharmaceutica Sinica 20020801

• Computer simulations of trypanosomal nucleoside hydrolase: determination of the protonation state of the bound transition-state analogue.

  Journal of the American Chemical Society 20020731

• Identification of the dITP- and XTP-hydrolyzing protein from Escherichia coli.

  Journal of biochemistry and molecular biology 20020731

• Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase.

  Biochimica et biophysica acta 20020729

• Functional importance of nucleotide identities within the pea atp9 mitochondrial promoter sequence.

  Journal of molecular biology 20020726

• Substrate specificity and sequence preference of G:T mismatch repair: incision at G:T, O6-methylguanine:T, and G:U mispairs in DNA by human cell extracts.

  Biochemistry 20020723

• Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites.

  The Journal of biological chemistry 20020719

• Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.

  Biochimica et biophysica acta 20020718

• Targeting the cell cycle for cancer therapy.

  British journal of cancer 20020715

• Targeted strand scission of DNA substrates by a tricopper(II) coordination complex.

  Journal of the American Chemical Society 20020710

• Bistranded oxidized purine damage clusters: induced in DNA by long-wavelength ultraviolet (290-400 nm) radiation?

  Biochemistry 20020709

• Importance of phosphate contacts for sequence recognition by EcoRI restriction enzyme.

  Biochemical and biophysical research communications 20020705

• Current progress in suicide gene therapy for cancer.

  World journal of surgery 20020701

• Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency.

  American journal of human genetics 20020701

• An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).

  American journal of physiology. Cell physiology 20020701

• The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.

  Molecular pharmacology 20020701

• Effects of angiotensin II infusion on renal excretion of purine bases and oxypurinol.

  Metabolism: clinical and experimental 20020701

• The physiology of endothelial xanthine oxidase: from urate catabolism to reperfusion injury to inflammatory signal transduction.

  Microcirculation (New York, N.Y. : 1994) 20020701

• The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression.

  Molecular endocrinology (Baltimore, Md.) 20020701

• Center for Synchrotron Biosciences' U2B beamline: an international resource for biological infrared spectroscopy.

  Journal of synchrotron radiation 20020701

• Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: preservation of intracellular ATP level.

  Experimental neurology 20020701

• Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK.

  QJM : monthly journal of the Association of Physicians 20020701

• Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease.

  Thorax 20020701

• Impact of stem cell source and conditioning regimen on erythrocyte recovery kinetics after allogeneic haematopoietic stem cell transplantation from an ABO-incompatible donor.

  British journal of haematology 20020701

• Aristolochic acid as a probable human cancer hazard in herbal remedies: a review.

  Mutagenesis 20020701

• Multiple pulmonary nodules: an unusual presentation of fludarabine pulmonary toxicity: case report and review of literature.

  American journal of hematology 20020701

• Synthesis of analogs of L-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020701

• Exposure-disease continuum for 2-chloro-2'-deoxyadenosine (2-CdA), a prototype teratogen: induction of lumbar hernia in the rat and species comparison for the teratogenic responses.

  Teratology 20020701

• Symptomatic hypoglycemia in children receiving oral purine analogues for treatment of childhood acute lymphoblastic leukemia.

  Medical and pediatric oncology 20020701

• Nucleoside analogues and nucleobases in cancer treatment.

  The Lancet. Oncology 20020701

• Bias of purine stretches in sequenced chromosomes.

  Computers & chemistry 20020701

• Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro.

  Anti-cancer drugs 20020701

• PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site.

  The Journal of biological chemistry 20020628

• Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif.

  Journal of molecular biology 20020628

• Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients.

  Neurology 20020625

• Hepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinase.

  FEBS letters 20020619

• A point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: role of oligomerization in catalysis.

  FEBS letters 20020619

• A novel uracil-DNA glycosylase with broad substrate specificity and an unusual active site.

  The EMBO journal 20020617

• [Experience with fludarabine treatment and review of the literature].

  Orvosi hetilap 20020616

• Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions.

  The Journal of biological chemistry 20020614

• Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae.

  The Journal of biological chemistry 20020607

• Roscovitine inhibits ongoing DNA synthesis in human cervical cancer.

  Cancer letters 20020606

• Determination of acyclovir in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605

• Chemical composition and flavor of ecuadorian cocoa liquor.

  Journal of agricultural and food chemistry 20020605

• Development of photo-crosslinking reagents for protein kinase-substrate interactions.

  FEBS letters 20020605

• 9-[(Hydroxymethyl)phenyl]adenines: new aryladenine substrates of adenosine deaminase.

  Bioorganic & medicinal chemistry letters 20020603

• Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation of the enzyme.

  Biochimica et biophysica acta 20020603

• Evidence for swelling-induced adenosine and adenine nucleotide release in rat cerebral cortex exposed to monocarboxylate-containing or hypotonic artificial cerebrospinal fluids.

  Neurochemistry international 20020601

• Novel missense mutation in the purine nucleoside phosphorylase gene in a Japanese patient with purine nucleoside phosphorylase deficiency.

  Pediatrics international : official journal of the Japan Pediatric Society 20020601

• Clustered DNA damages induced by x rays in human cells.

  Radiation research 20020601

• Proton NMR studies of 5'-d-(TC)(3) (CT)(3) (AG)(3)-3'--a paperclip triplex: the structural relevance of turns.

  Biophysical journal 20020601

• FTIR and UV spectroscopy studies of triplex formation between pyrimidine methoxyethylphosphoramidates alpha-oligodeoxynucleotides and ds DNA targets.

  Journal of biomolecular structure & dynamics 20020601

• Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia.

  Leukemia 20020601

• Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models.

  Gene therapy 20020601

• Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition.

  Current drug targets 20020601

• Current treatment of follicular non-Hodgkin's lymphoma.

  European journal of cancer (Oxford, England : 1990) 20020601

• Cancer chemotherapy and heterocyclic compounds.

  Current medicinal chemistry 20020601

• Chronic lymphocytic leukemia.

  Current treatment options in oncology 20020601

• A phase I study of AIT-082 in healthy elderly volunteers.

  Journal of molecular neuroscience : MN 20020601

• Variation between sheep in renal excretion of [14C]allantoin.

  The British journal of nutrition 20020601

• Purification and characterization of recombinant Plasmodium falciparum adenylosuccinate synthetase expressed in Escherichia coli.

  Protein expression and purification 20020601

• Diadenosine pentaphosphate vasodilates the forearm vascular bed: inhibition by theophylline and augmentation by dipyridamole.

  Clinical pharmacology and therapeutics 20020601

• Enhanced analysis of purine and pyrimidine bases by the use of double-strand polyaniline coatings in micellar electrokinetic capillary chromatography.

  Electrophoresis 20020601

• Effects of chemical ischemia on purine nucleotides, free radical generation, lipids peroxidation and intracellular calcium levels in C2C12 myotube derived from mouse myocytes.

  The Journal of veterinary medical science 20020601

• Myelodysplasia terminating in acute myeloid leukemia in a hairy cell leukemia patient treated with 2-deoxycoformycin.

  Leukemia & lymphoma 20020601

• Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine.

  Free radical research 20020601

• Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs.-host disease: the role of dGTP in antiproliferative action of BCX-1777.

  International immunopharmacology 20020601

• Recent aspects of oxidative DNA damage: guanine lesions, measurement and substrate specificity of DNA repair glycosylases.

  Biological chemistry 20020601

• Dietary fiber suppresses elevations of uric acid and allantoin in serum and urine induced by dietary RNA and increases its excretion to feces in rats.

  Journal of nutritional science and vitaminology 20020601

• [Effects of exogenous nucleotides on the proliferation and migration of intestinal epithelial cells].

  Wei sheng yan jiu = Journal of hygiene research 20020601

• [Study on the silica-induced cytotoxicity and hprt gene mutagenisis in rat lung fibroblasts and alveolar type II epithelial cells].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20020601

• Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.

  Journal of medicinal chemistry 20020523

• Molecular identification of a renal urate anion exchanger that regulates blood urate levels.

  Nature 20020523

• On the competition of the purine bases, functionalities of peptide side chains, and protecting agents for the coordination sites of dicationic cisplatin derivatives.

  Journal of the American Chemical Society 20020522

• Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation.

  Biochemistry 20020521

• The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.

  Biochemistry 20020521

• Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells.

  International journal of cancer 20020520

• Recognition of HNA and 1,5-anhydrohexitol nucleotides by DNA metabolizing enzymes.

  Biochimica et biophysica acta 20020520

• First synthesis and anticancer activity of phosmidosine and its related compounds.

  The Journal of organic chemistry 20020517

• 'Fleximers'. Design and synthesis of a new class of novel shape-modified nucleosides(1).

  The Journal of organic chemistry 20020517

• Polyploid measles virus with hexameric genome length.

  The EMBO journal 20020515

• New approaches in the development of DNA sensors: hybridization and electrochemical detection of DNA and RNA at two different surfaces.

  Bioelectrochemistry (Amsterdam, Netherlands) 20020515

• Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography.

  Journal of molecular biology 20020510

• Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.

  The Journal of biological chemistry 20020503

• Total synthesis of spicamycin.

  The Journal of organic chemistry 20020503

• Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after administration of various labelled precursors.

  Life sciences 20020503

• CD80 antigen expression as a predictor of ex vivo chemosensitivity in chronic lymphocytic leukemia.

  Leukemia research 20020501

• Effects of a P-glycoprotein inhibitor on brain and plasma concentrations of anti-human immunodeficiency virus drugs administered in combination in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20020501

• Loss of urate oxidase activity in hominoids and its evolutionary implications.

  Molecular biology and evolution 20020501

• Transcription-targeted gene therapy for androgen-independent prostate cancer.

  Cancer gene therapy 20020501

• Mechanisms of apoptosis induced by purine nucleosides in astrocytes.

  Glia 20020501

• Receptor regulatory properties evident in the molecular similarity of dopamine receptor ligands and purine nucleotides.

  The Journal of pharmacy and pharmacology 20020501

• Theacrine (1,3,7,9-tetramethyluric acid) synthesis in leaves of a Chinese tea, kucha (Camellia assamica var. kucha).

  Phytochemistry 20020501

• The pivotal role of guanine phosphoribosyltransferase in purine salvage by Giardia lamblia.

  Molecular microbiology 20020501

• Arsenate reductase II. Purine nucleoside phosphorylase in the presence of dihydrolipoic acid is a route for reduction of arsenate to arsenite in mammalian systems.

  Chemical research in toxicology 20020501

• Cytotoxic efficacy of bendamustine in human leukemia and breast cancer cell lines.

  Journal of cancer research and clinical oncology 20020501

• The distribution of purine P2X(2) receptors in the guinea-pig enteric nervous system.

  Histochemistry and cell biology 20020501

• Characteristics of Na(+)-dependent intestinal nucleoside transport in the pig.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020501

• Gene abnormalities in patients with hemophagocytic lymphohistiocytosis.

  The Israel Medical Association journal : IMAJ 20020501

• Treatment of lethal cowpox virus respiratory infections in mice with 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine and its orally active diacetate ester prodrug.

  Antiviral research 20020501

• High-dose methylprednisolone therapy in multiple sclerosis increases serum uric acid levels.

  Clinical chemistry and laboratory medicine 20020501

• Dyshormonal disorders in gout: experimental and clinical studies.

  Bulletin of experimental biology and medicine 20020501

• Calf spleen purine nucleoside phosphorylase: complex kinetic mechanism, hydrolysis of 7-methylguanosine, and oligomeric state in solution.

  Biochimica et biophysica acta 20020429

• Functional cloning, heterologous expression, and purification of two different N-deoxyribosyltransferases from Lactobacillus helveticus.

  The Journal of biological chemistry 20020426

• Functional studies of potential intrastrand triplex elements in the Escherichia coli genome.

  Journal of molecular biology 20020426

• Preconditioning of rat hearts by adenosine A1 or A3 receptor activation.

  European journal of pharmacology 20020426

• A genome sequence survey of the mollicute corn stunt spiroplasma Spiroplasma kunkelii.

  FEMS microbiology letters 20020423

• Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs.

  British journal of cancer 20020422

• Determination of purine and pyrimidine bases in DNA by micellar electrokinetic capillary chromatography with electrochemical detection.

  Journal of chromatography. A 20020419

• Sequestering of Eu(III) by a GAAA RNA tetraloop.

  Journal of the American Chemical Society 20020410

• Identification of a novel mycobacterial transcriptional regulator and its involvement in growth rate dependence and stringent control.

  FEMS microbiology letters 20020409

• Covalent analogues of DNA base-pairs and triplets. Part 2: synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds.

  Bioorganic & medicinal chemistry letters 20020408

• Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts.

  The Journal of biological chemistry 20020405

• Kinetics of hydrolysis of 8-(arylamino)-2'-deoxyguanosines.

  The Journal of organic chemistry 20020405

• Fast, efficient capillary electrophoresis method for measuring nucleotide degradation and metabolism.

  Journal of chromatography. A 20020405

• Severe energy deprivation of human hibernating myocardium as possible common pathomechanism of contractile dysfunction, structural degeneration and cell death.

  Journal of the American College of Cardiology 20020403

• How does the mitochondrial ADP/ATP carrier distinguish transportable ATP and ADP from untransportable AMP and GTP?Dynamic modeling of the recognition/translocation process in the major substrate binding region.

  Biochimica et biophysica acta 20020403

• A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines.

  The EMBO journal 20020402

• Synthesis and evaluation of organosilicon inhibitors of active purine transport in human osteoblasts.

  Chembiochem : a European journal of chemical biology 20020402

• Ophidian envenomation strategies and the role of purines.

  Toxicon : official journal of the International Society on Toxinology 20020401

• Activation of nonspecific cytotoxic cells (NCC) with synthetic oligodeoxynucleotides and bacterial genomic DNA: binding, specificity and identification of unique immunostimulatory motifs.

  Developmental and comparative immunology 20020401

• Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels.

  Neurochemistry international 20020401

• Developmentally regulated expression of a cell surface class I nuclease in Leishmania mexicana.

  International journal for parasitology 20020401

• Role of mizoribine in renal transplantation.

  Pediatrics international : official journal of the Japan Pediatric Society 20020401

• Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis.

  Acta neuropathologica 20020401

• Effect of inosine on the plasma concentration of uridine and purine bases.

  Metabolism: clinical and experimental 20020401

• Properties of Na(+)-dependent nucleoside transport in the proximal and distal small intestine of cows.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020401

• Pharmacokinetics of acyclovir in immunocompromized children with leukopenia and mucositis after chemotherapy: can intravenous acyclovir be substituted by oral valacyclovir?

  Medical and pediatric oncology 20020401

• Distinguishing 'looped-out' and 'stacked-in' DNA bulge conformation using fluorescent 2-aminopurine replacing a purine base.

  Journal of biomolecular structure & dynamics 20020401

• Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury.

  Annals of surgery 20020401

• Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes.

  Journal of hepatology 20020401

• Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan, and antithymocyte globulin against advanced/refractory acute leukemia/lymphoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

• Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurement in gamma-irradiated isolated DNA.

  Chemical research in toxicology 20020401

• Short-term effects of angiotensin II receptor blockade in patients with primary glomerulonephritis: pilot study.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20020401

• Interaction of pemetrexed disodium (ALIMTA, multitargeted antifolate) and irradiation in vitro.

  International journal of radiation oncology, biology, physics 20020401

• The involvement of smooth muscle P2X receptors in the prolonged vasorelaxation response to purine nucleotides in the rat mesenteric arterial bed.

  British journal of pharmacology 20020401

• A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis.

  The Plant cell 20020401

• Deletion of dinucleotide repeat (Delta 14 allele) in the methylthioadenosine phosphorylase (MTAP) promoter and the allelotype of MTAP promoter in the Japanese population.

  Japanese journal of cancer research : Gann 20020401

• Mycophenolate mofetil: selective T cell inhibition.

  The American journal of the medical sciences 20020401

• Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia.

  The Journal of veterinary medical science 20020401

• Pemetrexed: a promising new treatment for breast cancer.

  Seminars in oncology 20020401

• 5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons.

  Journal of neurochemistry 20020401

• Effect of octreotide acetate on the plasma concentration and urinary excretion of uridine and purine bases.

  Endocrine journal 20020401

• Cold storage of rabbit thoracic aorta in University of Wisconsin solution attenuates P2Y(2) purine receptors.

  Cryobiology 20020401

• A DNA-electrochemical biosensor for screening environmental damage caused by s-triazine derivatives.

  Analytical and bioanalytical chemistry 20020401

• Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts.

  Journal of the American Chemical Society 20020327

• Direct protection of inosine on PC12 cells against zinc-induced injury.

  Neuroreport 20020325

• Benzimidazole-4,7-diones as inhibitors of protozoal (Toxoplasma gondii) purine nucleoside phosphorylase.

  Bioorganic & medicinal chemistry letters 20020325

• Purine and pyrimidine salvage in whole rat brain. Utilization of ATP-derived ribose-1-phosphate and 5-phosphoribosyl-1-pyrophosphate generated in experiments with dialyzed cell-free extracts.

  The Journal of biological chemistry 20020322

• Influence of d orbital occupation on the binding of metal ions to adenine.

  Journal of the American Chemical Society 20020320

• Mass spectrometric assays for the tandem lesion 8,5'-cyclo-2'-deoxyguanosine in mammalian DNA.

  Biochemistry 20020319

• The role of reperfusion injury in photodynamic therapy with 5-aminolaevulinic acid--a study on normal rat colon.

  British journal of cancer 20020318

• Childhood hyperuricemia and acute renal failure resulting from a missense mutation in the HPRT gene.

  American journal of medical genetics 20020315

• alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties.

  Journal of the American Chemical Society 20020313

• [The benefits of new immunosuppressive treatments in adult kidney transplantation].

  Presse medicale (Paris, France : 1983) 20020309

• A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1.

  The Journal of biological chemistry 20020308

• Manipulation of plasma uric acid in broiler chicks and its effect on leukocyte oxidative activity.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020301

• A colorimetric assay for the quantitation of free adenine applied to determine the enzymatic activity of ribosome-inactivating proteins.

  Analytical biochemistry 20020301

• Nucleosteroids: carbocyclic nucleoside analogs of androst-4-en-17 beta-ol.

  Steroids 20020301

• New developments in the treatment of inflammatory bowel disease.

  Expert opinion on investigational drugs 20020301

• 3,4-Dihydro-6-methyl-3-beta-D-ribofuranosyl-4,5'-cyclo-9H-imidazo[1,2-a]purin-9-one hydrate.

  Acta crystallographica. Section C, Crystal structure communications 20020301

• Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cells.

  European journal of biochemistry 20020301

• Purine biosynthesis. Big in cell division, even bigger in nitrogen assimilation.

  Plant physiology 20020301

• Treatment of children with Langerhans cell histiocytosis with 2-chlorodeoxyadenosine.

  American journal of hematology 20020301

• Leukodystrophy and CSF purine abnormalities associated with isolated 3-methylcrotonyl-CoA carboxylase deficiency.

  Metabolic brain disease 20020301

• Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors.

  Chemical & pharmaceutical bulletin 20020301

• Hypomethylation and multiple sclerosis, the susceptibility factor?

  Neurologia (Barcelona, Spain) 20020301

• Sodium dependence of nitrofurantoin active transport across mammary epithelia and effects of dipyridamole, nucleosides, and nucleobases.

  Pharmaceutical research 20020301

• P2 receptor modulation and cytotoxic function in cultured CNS neurons.

  Neuropharmacology 20020301

• [Chimeric yeast prions with unstable inheritance].

  Genetika 20020301

• The role of nucleoside analogues in the treatment of chronic lymphocytic leukemia-lessons learned from prospective randomized trials.

  Leukemia & lymphoma 20020301

• Purine composition of the crystalline cytoplasmic inclusions of Paramecium tetraurelia.

  Protist 20020301

• Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach.

  Antiviral chemistry & chemotherapy 20020301

• Characterization of the Hansenula polymorpha PUR7 gene and its use as selectable marker for targeted chromosomal integration.

  FEMS yeast research 20020301

• Adenosine as a neuroprotectant: therapeutic perspectives.

  Expert review of neurotherapeutics 20020301

• Correlation between chromosome damage and apoptosis induced by fludarabine and idarubicin in normal human lymphocytes.

  Toxicology 20020227

• Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.

  Brain research. Developmental brain research 20020227

• Specificity analysis of the conserved hexanucleotides for the replication of bamboo mosaic potexvirus RNA.

  Virus research 20020226

• Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020215

• 8-Chloro-dGTP, a hypochlorous acid-modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog.

  FEBS letters 20020213

• Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y(2)-receptors.

  British journal of cancer 20020212

• Protonation studies of modified adenine and adenine nucleotides by theoretical calculations and (15)N NMR.

  The Journal of organic chemistry 20020208

• Anoxia-induced changes in purine nucleoside metabolism of in vitro aged human fibroblasts.

  Life sciences 20020208

• The sodium ions inside a lipophilic G-quadruplex channel as probed by solid-state (23)Na NMR.

  Journal of the American Chemical Society 20020206

• L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress.

  American journal of physiology. Endocrinology and metabolism 20020201

• Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues.

  The Biochemical journal 20020201

• Overexpression of Escherichia coli genes encoding nucleoside phosphorylases in the pET/Bl21(DE3) system yields active recombinant enzymes.

  Protein expression and purification 20020201

• Endothelial cell compatibility of azithromycin and erythromycin.

  The Journal of antimicrobial chemotherapy 20020201

• Metabolic treatment of hyperuricosuric autism.

  Progress in neuro-psychopharmacology & biological psychiatry 20020201

• Platinum complexes of oxopurines: cis-bis(theophyllinato-N7)bis(triphenylphosphine)platinum(II) and cis-chloro(theobrominato-N1)bis(triphenylphosphine)platinum(II) ethanol hemisolvate.

  Acta crystallographica. Section C, Crystal structure communications 20020201

• Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex.

  Structure (London, England : 1993) 20020201

• Conceptual aspects of combining rituximab and Campath-1H in the treatment of chronic lymphocytic leukemia.

  Seminars in oncology 20020201

• Formation and thermodynamic stability of intermolecular (R*R*Y) DNA triplex in GAA/TTC repeats associated with Freidreich's ataxia.

  Journal of biomolecular structure & dynamics 20020201

• Using a Euclid distance discriminant method to find protein coding genes in the yeast genome.

  Computers & chemistry 20020201

• Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: a selective approach.

  Electrophoresis 20020201

• Primordial coding of amino acids by adsorbed purine bases.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020201

• Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins.

  Genes to cells : devoted to molecular & cellular mechanisms 20020201

• Effect of strand orientation on the interaction of berenil with DNA triple helices.

  European biophysics journal : EBJ 20020201

• Serum xanthine oxidase: origin, regulation, and contribution to control of trypanosome parasitemia.

  Antioxidants & redox signaling 20020201

• Large-cell transformation of chronic lymphocytic leukemia and follicular lymphoma during or soon after treatment with fludarabine-rituximab-containing regimens: natural history- or therapy-related complication?

  European journal of haematology 20020201

• Chronic lymphocytic leukaemia--the haematologic basis for diagnosis and treatment.

  Hematology (Amsterdam, Netherlands) 20020201

• The efflux of purine nucleobases and nucleosides from the rat brain.

  Neuroscience letters 20020125

• Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotides.

  The Journal of organic chemistry 20020125

• Adenine-aptamer complexes: a bipartite RNA site that binds the adenine nucleic base.

  The Journal of biological chemistry 20020118

• Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.

  Journal of molecular biology 20020118

• Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release.

  Blood 20020115

• Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain.

  Biochemical pharmacology 20020115

• Chemical modification of the third strand: differential effects on purine and pyrimidine triple helix formation.

  Biochemistry 20020108

• Analysis of purines and pyrimidines by mixed partition-adsorption normal-phase high-performance liquid chromatography.

  Journal of chromatography. A 20020104

• Rebek imides and their adenine complexes: preferences for Hoogsteen binding in the solid state and in solution.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020104

• Superoxide activates mitochondrial uncoupling proteins.

  Nature 20020103

• Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase.

  FEBS letters 20020102

• Synthesis of novel (2R,4R)- and (2S,4S)-iso dideoxynucleosides with exocyclic methylene as potential antiviral agents.

  Bioorganic & medicinal chemistry 20020101

• Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart.

  Journal of cardiovascular pharmacology 20020101

• Structural analyses reveal two distinct families of nucleoside phosphorylases.

  The Biochemical journal 20020101

• Synergistic cell-killing effect of a combination of hyperthermia and heavy ion beam irradiation: in expectation of a breakthrough in the treatment of refractory cancers (review).

  International journal of molecular medicine 20020101

• HPLC determination of thiopurine nucleosides and nucleotides in vivo in lymphoblasts following mercaptopurine therapy.

  Clinical chemistry 20020101

• Molecular cloning of Trypanosoma brucei CK2 catalytic subunits: the alpha isoform is nucleolar and phosphorylates the nucleolar protein Nopp44/46.

  Molecular and biochemical parasitology 20020101

• Partial hypoxanthine-Guanine phosphoribosyltransferase deficiency as the unsuspected cause of renal disease spanning three generations: a cautionary tale.

  Pediatrics 20020101

• Inflammatory bowel disease.

  Endoscopy 20020101

• The metabolism of 2-methyladenosine in Mycobacterium smegmatis.

  Microbiology (Reading, England) 20020101

• Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails.

  Journal of acquired immune deficiency syndromes (1999) 20020101

• Linkage between toxin production and purine biosynthesis in Clostridium difficile.

  Journal of medical microbiology 20020101

• Characterization of the substrate specificity of a human 5-hydroxymethyluracil glycosylase activity.

  Chemical research in toxicology 20020101

• [The pyrimidine-biosynthetic (pyr) gene cluster in trypanosomes].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20020101

• Nucleotide-mediated relaxation in guinea-pig aorta: selective inhibition by MRS2179.

  British journal of pharmacology 20020101

• Progress towards the discovery of xanthine oxidase inhibitors.

  Current medicinal chemistry 20020101

• Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy.

  BMC cancer 20020101

• [Pyrimidine oligodeoxyxylonucleotides form triplexes with purine DNA in neutral media].

  Molekuliarnaia biologiia 20020101

• Potential therapeutic targets in the rapidly expanding field of purinergic signalling.

  Clinical medicine (London, England) 20020101

• Effects of high inspired oxygen fraction during elective caesarean section under spinal anaesthesia on maternal and fetal oxygenation and lipid peroxidation.

  British journal of anaesthesia 20020101

• Untranslated regions of mRNAs.

  Genome biology 20020101

• [Gout: current views. Stage oriented treatment].

  Klinicheskaia meditsina 20020101

• Persistent developmental delay despite successful bone marrow transplantation for purine nucleoside phosphorylase deficiency.

  Journal of pediatric hematology/oncology 20020101

• RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure.

  BMC bioinformatics 20020101

• Methylenetetrahydrofolate reductase: a common human polymorphism and its biochemical implications.

  Chemical record (New York, N.Y.) 20020101

• Human sperm immobilizing activity of aminophenyl arsenic acid and its N-substituted quinazoline, pyrimidine, and purine derivatives: protective effect of glutathione.

  Reproductive toxicology (Elmsford, N.Y.) 20020101

• Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells.

  Blood cells, molecules & diseases 20020101

• Synthesis, antiviral and cytostatic activities, of carbocyclic nucleosides incorporating a modified cyclopentane ring. IV. Adenosine and uridine analogues.

  Nucleosides, nucleotides & nucleic acids 20020101

• Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: developed pressure may not be an appropriate end-point for studies of preconditioning.

  Basic research in cardiology 20020101

• Anti-adenosine deaminase antibodies in lupus erythematosus.

  Lupus 20020101

• 6-thioguanine in the treatment of psoriasis: a case report and literature review.

  Journal of cutaneous medicine and surgery 20020101

• Xanthine oxidase activation in mild gestational hypertension.

  Hypertension in pregnancy 20020101

• Evolution of gene fusions: horizontal transfer versus independent events.

  Genome biology 20020101

• Targeting fragile X.

  Genome biology 20020101

• Potential role of purinergic signalling in cochlear pathology.

  Audiology & neuro-otology 20020101

• [Riboflavin overproduction in 4-aminopyrazole[3,4-d]pyrimidine-treated yeast Pichia guilliermondii].

  Prikladnaia biokhimiia i mikrobiologiia 20020101

• European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.9.1. Haematological complications. Anaemia.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020101

• Gene discovery within the planctomycete division of the domain Bacteria using sequence tags from genomic DNA libraries.

  Genome biology 20020101

• Waldenström's macroglobulinaemia: current therapy and future approaches.

  BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20020101

• Molecular action of methotrexate in inflammatory diseases.

  Arthritis research 20020101

• Epidemiology of hairy cell leukemia in Iceland.

  The hematology journal : the official journal of the European Haematology Association 20020101

• Oral self-mutilation in the Lesch-Nyhan syndrome.

  ASDC journal of dentistry for children 20020101

• Novel cyanine dye-labeled dideoxynucleoside triphosphates for DNA sequencing.

  Bioconjugate chemistry 20020101

• Energy metabolism during microsurgical transfer of human skeletal muscle assessed by high-pressure liquid chromatography and by 31P-nuclear magnetic resonance.

  Scandinavian journal of plastic and reconstructive surgery and hand surgery 20020101

• [Clinico-hematological effectiveness in losartan for treating hypertensive patients].

  Likars'ka sprava 20020101

• Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios.

  BMC biotechnology 20020101

• Pervasive properties of the genomic signature.

  BMC genomics 20020101

• Monocarboxylate transporters and lactate metabolism in equine athletes: a review.

  Acta veterinaria Scandinavica 20020101

• Current and developing chemotherapy for CLL.

  Medical oncology (Northwood, London, England) 20020101

• [The increasing mutagenic effect of nitrosoguanidine under the influence of modified bases during inhibition of repair AGT enzyme in mammalian somatic cells in vitro].

  TSitologiia i genetika 20020101

• Hematopoietic stem-cell transplantation for Hodgkin's disease (HD): current status.

  Cytotherapy 20020101

• Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase.

  BMC cell biology 20020101

• Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease.

  Journal of biomedical science 20020101

• Artificial ribonucleases: efficient and specific in vitro cleavage of human c-raf-1 RNA.

  Bioconjugate chemistry 20020101

• The effects of Neotrofin on septodentate sprouting after unilateral entorhinal cortex lesions in rats.

  Restorative neurology and neuroscience 20020101

• Adenosine 5'-triphosphate axis in obstructive airway diseases.

  American journal of therapeutics 20020101

• Waldenström's macroglobulinemia.

  Clinical journal of oncology nursing 20020101

• Specificity of DNA triple helix formation analyzed by a FRET assay.

  BMC biochemistry 20020101

• Purine nucleosides bearing 1-alkynyl chains as adenosine receptor agonists.

  Current pharmaceutical design 20020101

• Applications of adenosine receptor ligands in medical imaging by positron emission tomography.

  Current pharmaceutical design 20020101

• Control of pyrimidine synthesis in Pseudomonas fragi.

  Letters in applied microbiology 20020101

• [Features of the kinetics of accumulating entomocidal exotoxins of Bacillus thuringiensis subsp. thuringiensis during fermentation stage of bitoxibacillin production].

  Prikladnaia biokhimiia i mikrobiologiia 20020101

• Evidence for non-independent gating of P2X2 receptors expressed in Xenopus oocytes.

  BMC neuroscience 20020101

• Exploring the conditional coregulation of yeast gene expression through fuzzy k-means clustering.

  Genome biology 20020101

• Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands.

  Genome biology 20020101

• The society of genes: networks of functional links between genes from comparative genomics.

  Genome biology 20020101

• Finding signals that regulate alternative splicing in the post-genomic era.

  Genome biology 20020101

• Inosine stimulates axon growth in vitro and in the adult CNS.

  Progress in brain research 20020101

• Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101

• Analysis of relative positions of ribonucleotide bases in a crystal structure of ribosome.

  Nucleosides, nucleotides & nucleic acids 20020101

• Oxidant injury in neonatal erythrocytes during the perinatal period.

  Acta paediatrica (Oslo, Norway : 1992). Supplement 20020101

• [Metabolic syndrome from the point of view of a cardiologist: diagnosis, non drug and drug treatment].

  Kardiologiia 20020101

• [Pathogenetic role of moxonidine in the treatment of hypertension in postmenopausal women].

  Kardiologiia 20020101

• Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum.

  BMC neuroscience 20020101

• Mutations in the Lactococcus lactis Ll.LtrB group II intron that retain mobility in vivo.

  BMC molecular biology 20020101

• Kelley-Seegmiller syndrome in a patient with complete hypoxanthine-guanine phosphoribosyltransferase deficiency.

  Clinical and experimental rheumatology 20020101

• Allopurinol for chronic prostatitis.

  The Cochrane database of systematic reviews 20020101

• [Evaluation of hypoxic state in experimental animals induced by Yersinia pestis antigens].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101

• [Coding in molecular biology and radiation].

  Radiatsionnaia biologiia, radioecologiia 20020101

• Life before RNA.

  Astrobiology 20020101

• The mitochondrial uncoupling proteins.

  Genome biology 20020101

• Plasma 5'-nucleotidase activities and uric acid levels in women with pre-eclampsia.

  Gynecologic and obstetric investigation 20020101

• [The hematology clinic].

  Revue medicale de Bruxelles 20020101

• [The study and comparative evaluation of the actoprotective activity of ATF-LONG in experiment].

  Likars'ka sprava 20020101

• Purine degradation in the edible mushroom Agaricus bisporus.

  Folia microbiologica 20020101

• Elevation of antioxidant potency in mice brain by low-dose X-ray irradiation and its effect on Fe-NTA-induced brain damage.

  Physiological chemistry and physics and medical NMR 20020101

• Substrate recognition by the human MTH1 protein.

  Nucleic acids research. Supplement (2001) 20020101

• Synthesis and properties of N-t-butylaminoxyl nucleosides.

  Nucleic acids research. Supplement (2001) 20020101

• Purine and pyrimidine nucleotide synthesis and metabolism.

  The arabidopsis book 20020101

• Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors.

  Journal of medicinal chemistry 20011220

• Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.

  Journal of medicinal chemistry 20011220

• 6-bromopurine nucleosides as reagents for nucleoside analogue synthesis.

  The Journal of organic chemistry 20011214

• A nonspecific nucleoside hydrolase from Leishmania donovani: implications for purine salvage by the parasite.

  Gene 20011212

• A rationally designed oligopeptide shows significant conformational changes upon binding to sulphate ions.

  Biosensors & bioelectronics 20011201

• Evolving medical therapies for Crohn's disease.

  Current gastroenterology reports 20011201

• Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site.

  Nature structural biology 20011201

• Small-molecule metabolism: an enzyme mosaic.

  Trends in biotechnology 20011201

• Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro.

  International journal of molecular medicine 20011201

• A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.

  International journal of oncology 20011201

• Scanning mutagenesis identifies critical residues in the rinderpest virus genome promoter.

  The Journal of general virology 20011201

• Multinuclear magnetic resonance spectroscopy studies of brain purines in major depression.

  The American journal of psychiatry 20011201

• Blood transfusion causes deterioration in liver regeneration after partial hepatectomy in rats.

  The Journal of surgical research 20011201

• Rituximab, a chimaeric anti-CD20 monoclonal antibody, in the treatment of hairy cell leukaemia.

  British journal of haematology 20011201

• The role of purine analogue combinations in the management of acute leukemias.

  Hematological oncology 20011201

• 3,7-Dimethylguanine, a new purine from a Philippine sponge Zyzzya fuliginosa.

  Chemical & pharmaceutical bulletin 20011201

• Enzymatic properties of sialic acid binding lectin from Rana catesbeiana modified with a water-soluble carbodiimide in the presence of various nucleophiles.

  Biological & pharmaceutical bulletin 20011201

• Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses.

  Cancer immunology, immunotherapy : CII 20011201

• Elevation of extracellular glutamate in the final, ischemic stage of progressive epidural mass lesion in cats.

  Journal of neurotrauma 20011201

• A handy detection cell for end-column electrochemical detection in capillary electrophoresis.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011201

• Human aldehyde dehydrogenase catalytic activity and structural interactions with coenzyme analogs.

  Journal of biomolecular structure & dynamics 20011201

• The purine degradation pathway: possible role in paralytic shellfish toxin metabolism in the cyanobacterium Planktothrix sp. FP1.

  Environment international 20011201

• MRP subfamily transporters and resistance to anticancer agents.

  Journal of bioenergetics and biomembranes 20011201

• The oxpA5 mutation of Aspergillus nidulans is an allele of adB, the gene encoding adenylosuccinate synthetase.

  Molecular genetics and genomics : MGG 20011201

• Novel cross-strand three-purine stack of the highly conserved 5'-GA/AAG-5' internal loop at the 3'-end termini of Parvovirus genomes.

  Journal of biomolecular NMR 20011201

• [Hairy cell leukemia: report of 8 cases].

  La Tunisie medicale 20011201

• [Evaluation of glucose, insulin, C-peptide uric acid serum levels in patients with psoriasis].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20011201

• Sinusoidal endothelial cell injury by superoxide anion and iron in the Propionibacterium acnes-pretreated and lipopolysaccharide-stimulated rat liver.

  Liver 20011201

• Specific treatment of Chagas disease: current status and new developments.

  Current opinion in infectious diseases 20011201

• [Renal replacement therapy results in correction of plasma and erythrocyte adenine nucleotide abnormalities in patients with chronic renal failure].

  Polskie Archiwum Medycyny Wewnetrznej 20011201

• Absorption coefficient and purine photobleaching rate in colon mucosa during resonance Raman spectroscopy at 251 nm.

  Applied optics 20011201

• Syntheses of puromycin from adenosine and 7-deazapuromycin from tubercidin, and biological comparisons of the 7-aza/deaza pair.

  The Journal of organic chemistry 20011130

• A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine.

  Bioorganic & medicinal chemistry letters 20011119

• Quadruple intercalated G-6 stack: a possible motif in the fold-back structure of the Drosophila centromeric dodeca-satellite?

  Journal of molecular biology 20011116

• Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation.

  Analytical biochemistry 20011115

• Hypoxanthine-guanine phosphoribosyltransferase-deficiency produces aberrant neurite outgrowth of rodent neuroblastoma used to model the neurological disorder Lesch Nyhan syndrome.

  Neuroscience letters 20011113

• Abnormal development of hypoxanthine-guanine phosphoribosyltransferase-deficient CNS neuroblastoma.

  Brain research 20011109

• In vitro bioassays for anticancer drug screening: effects of cell concentration and other assay parameters on growth inhibitory activity.

  Cancer letters 20011108

• Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus.

  Journal of medicinal chemistry 20011108

• Synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine (FddA) via a purine 3'-deoxynucleoside.

  The Journal of organic chemistry 20011102

• Localization of the Plasmodium falciparum PfNT1 nucleoside transporter to the parasite plasma membrane.

  The Journal of biological chemistry 20011102

• Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes.

  Journal of molecular biology 20011102

• Indication, surgical technique and outcome of orthotopic renal transplantation.

  The Journal of urology 20011101

• Differential kinetics of transport of 2',3'-dideoxyinosine and adenosine via concentrative Na+ nucleoside transporter CNT2 cloned from rat blood-brain barrier.

  The Journal of pharmacology and experimental therapeutics 20011101

• Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells.

  The Journal of pharmacology and experimental therapeutics 20011101

• Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.

  Molecular pharmacology 20011101

• Variability of the CD36 gene in West Africa.

  Human mutation 20011101

• Azathioprine treatment and male fertility in inflammatory bowel disease.

  Gastroenterology 20011101

• Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma.

  Leukemia 20011101

• Structure-activity relationships of diadenosine polyphosphates (Ap(n)As), adenosine polyphospho guanosines (Ap(n)Gs) and guanosine polyphospho guanosines (Gp(n)Gs) at P2 receptors in the rat mesenteric arterial bed.

  British journal of pharmacology 20011101

• Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine.

  Alimentary pharmacology & therapeutics 20011101

• Cell cycle-dependent control of polarised development by a cyclin-dependent kinase-like protein in the Fucus zygote.

  Development (Cambridge, England) 20011101

• 5'-Adenosine monophosphate and adenosine metabolism, and adenosine responses in mouse, rat and guinea pig heart.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011101

• Elimination voltammetry of adenine and cytosine mixtures.

  Bioelectrochemistry (Amsterdam, Netherlands) 20011101

• Functional properties and responses to ischaemia-reperfusion in Langendorff perfused mouse heart.

  Experimental physiology 20011101

• Novel 6-substituted uracil analogs as inhibitors of the angiogenic actions of thymidine phosphorylase.

  Biochemical pharmacology 20011101

• Synthetic 1,4-anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.

  Anti-cancer drugs 20011101

• Secondary DNA structures as molecular targets for cancer therapeutics.

  Biochemical Society transactions 20011101

• A history of UCP1.

  Biochemical Society transactions 20011101

• Fragmentation of photomodified oligodeoxynucleotides adducted with metal ions in an electrospray-ionization ion-trap mass spectrometer.

  Journal of the American Society for Mass Spectrometry 20011101

• [Mitochondrial uncoupling protein as a target of pharmacotherapy for obesity].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011101

• Novel deoxynucleoside-phosphorylating enzymes in mycoplasmas: evidence for efficient utilization of deoxynucleosides.

  Molecular microbiology 20011101

• Caffeine and the G2/M block override: a concept resulting from a misleading cell kinetic delay, independent of functional p53.

  International journal of cancer 20011101

• Comment on 'new infrared spectra and tautomeric studies of purine and alpha L-alanine with an innovative sampling technique.'.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20011101

• Progress in CLL, chemotherapy, antibodies and transplantation.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011101

• Neurocognitive functioning in Lesch-Nyhan disease and partial hypoxanthine-guanine phosphoribosyltransferase deficiency.

  Journal of the International Neuropsychological Society : JINS 20011101

• Influence of ambient temperature on plasma ammonia and lactate accumulation during prolonged submaximal and self-paced running.

  European journal of applied physiology 20011101

• Synthesis and biological properties of C-2, C-8, N-9 substituted 6-(3-chloroanilino)purine derivatives as cyclin-dependent kinase inhibitors. Part II.

  Archiv der Pharmazie 20011101

• Advances in the chemistry and pharmacology of ecteinascidins, a promising new class of anti-cancer agents.

  Current medicinal chemistry. Anti-cancer agents 20011101

• Regioselective 2'-silylation of purine ribonucleosides for phosphoramidite RNA synthesis.

  Current protocols in nucleic acid chemistry 20011101

• Extracellular nucleotides induce arterial smooth muscle cell migration via osteopontin.

  Circulation research 20011026

• Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.

  The Journal of biological chemistry 20011019

• 'Fleximers'. Design and synthesis of two novel split nucleosides.

  Organic letters 20011004

• Catabolism of exogenous deoxyinosine in cultured epithelial amniotic cells.

  Biochimica et biophysica acta 20011003

• Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans.

  Mutation research 20011001

• Development of a bacterial screen for novel hypoxanthine-guanine phosphoribosyltransferase substrates.

  Journal of molecular microbiology and biotechnology 20011001

• Participation of ATP in cell volume regulation in the endothelium after hypotonic stress.

  Clinical and experimental pharmacology & physiology 20011001

• Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.

  Cardiovascular research 20011001

• The A3 adenosine receptor as a new target for cancer therapy and chemoprotection.

  Experimental cell research 20011001

• High-level expression and one-step purification of cyclic amidohydrolase family enzymes.

  Protein expression and purification 20011001

• Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4.

  Journal of applied microbiology 20011001

• Transactivation via RAR/RXR-Sp1 interaction: characterization of binding between Sp1 and GC box motif.

  Molecular endocrinology (Baltimore, Md.) 20011001

• In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense.

  Planta medica 20011001

• A calorimetric study of 3d metal ions-acyclovir interactions. The 2-hydroxyethoxymethyl group of acyclovir mimics the role of ribose in deoxy-guanosine and guanosine promoting the coordination through N(7).

  Journal of inorganic biochemistry 20011001

• Effect of norepinephrine on the urinary excretion of purine bases and oxypurinol.

  Metabolism: clinical and experimental 20011001

• Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases.

  Structure (London, England : 1993) 20011001

• Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (beta/alpha)8 barrel joins two active sites.

  Structure (London, England : 1993) 20011001

• Developmental variation of sugars, carboxylic acids, purine alkaloids, fatty acids, and endoproteinase activity during maturation of Theobroma cacao L. seeds.

  Journal of agricultural and food chemistry 20011001

• Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol.

  The Journal of rheumatology 20011001

• Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture.

  American journal of respiratory and critical care medicine 20011001

• Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011001

• Cardiac myocyte adenosine receptors and caveolae.

  Trends in cardiovascular medicine 20011001

• Fragile X syndrome and Friedreich's ataxia: two different paradigms for repeat induced transcript insufficiency.

  Brain research bulletin 20011001

• Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HbsAg carriers with lymphoid malignancies treated with chemotherapy.

  British journal of haematology 20011001

• Favourable response to therapy with the anti-CD20 monoclonal antibody rituximab in primary chronic cold agglutinin disease.

  British journal of haematology 20011001

• Chromosome and oxidative damage biomarkers in lymphocytes of Parkinson's disease patients.

  International journal of hygiene and environmental health 20011001

• Measurement of small scalar and dipolar couplings in purine and pyrimidine bases.

  Journal of biomolecular NMR 20011001

• Ordered biochemical program of gene expression in cancer cells.

  Biochemistry. Biokhimiia 20011001

• Successful treatment with low-dose splenic irradiation for massive splenomegaly in an elderly patient with hairy-cell leukemia.

  European journal of haematology 20011001

• Synthesis and analysis of RNA containing 6-trifluoromethylpurine ribonucleoside.

  Organic letters 20010920

• Expression of hMTH1 in the hippocampi of control and Alzheimer's disease.

  Neuroreport 20010917

• Effect of single mutations on the specificity of Escherichia coli FPG protein for excision of purine lesions from DNA damaged by free radicals.

  Free radical biology & medicine 20010915

• Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine.

  The Journal of biological chemistry 20010907

• Aromatic dienophiles. 1. A theoretical study of an inverse-electron demand Diels-Alder reaction between 2-aminopyrrole and 1,3,5-triazine.

  The Journal of organic chemistry 20010907

• Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings.

  Bioorganic & medicinal chemistry letters 20010903

• The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.

  The EMBO journal 20010903

• Stabilities and isomeric equilibria in solutions of monomeric metal-ion complexes of guanosine 5'-triphosphate (GTP4-) and inosine 5'-triphosphate (ITP4-) in comparison with those of adenosine 5'-triphosphate (ATP4-).

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010903

• The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR.

  Archives of biochemistry and biophysics 20010901

• The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.

  British journal of pharmacology 20010901

• Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.

  Acta crystallographica. Section D, Biological crystallography 20010901

• Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro.

  Hepatology (Baltimore, Md.) 20010901

• Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice.

  Carcinogenesis 20010901

• Macrophages require different nucleoside transport systems for proliferation and activation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901

• A novel parasite-derived suicide gene for cancer gene therapy with specificity for lung cancer cells.

  Human gene therapy 20010901

• Caffeine: a well known but little mentioned compound in plant science.

  Trends in plant science 20010901

• Profiles of purine and pyrimidine nucleotides in fresh and manufactured tea leaves.

  Journal of agricultural and food chemistry 20010901

• Mycophenolate mofetil treatment accelerates recovery from experimental allergic encephalomyelitis.

  International immunopharmacology 20010901

• Chronic T-cell lymphoproliferative disease expressing natural killer cell receptors: clinicopathological and molecular features.

  Cancer genetics and cytogenetics 20010901

• Concentrations of nucleotides, nucleosides, purine bases, oxypurines, uric acid, and neuron-specific enolase in the cerebrospinal fluid of children with sepsis.

  Journal of child neurology 20010901

• [Recent progress in the treatment of malignant lymphoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 20010901

• Effect of transketolase modifications on carbon flow to the purine-nucleotide pathway in Corynebacterium ammoniagenes.

  Applied microbiology and biotechnology 20010901

• Fulminant hepatitis B virus reactivation with concomitant listeriosis after fludarabine and rituximab therapy: case report.

  Annals of hematology 20010901

• [Establishment of human neuroectodermal tumor cell line (PFSK) with stable expression of xanthine oxidoreductase].

  Shi yan sheng wu xue bao 20010901

• Ribavirin: recent insights into antiviral mechanisms of action.

  Current opinion in drug discovery & development 20010901

• V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.

  Journal of molecular biology 20010831

• Effects of hypothermic machine perfusion on rat liver function depending on the route of perfusion.

  Transplantation 20010827

• Simultaneous determination of six adenyl purines in human plasma by high-performance liquid chromatography with fluorescence derivatization.

  Journal of chromatography. B, Biomedical sciences and applications 20010825

• Synthesis of bicyclic pyrimidine derivatives as ATP analogues.

  The Journal of organic chemistry 20010824

• Synthesis of 6-(2-thienyl)purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides.

  Bioorganic & medicinal chemistry letters 20010820

• Structure and dimerization of HIV-1 kissing loop aptamers.

  Journal of molecular biology 20010817

• Discovery of estrogen sulfotransferase inhibitors from a purine library screen.

  Journal of medicinal chemistry 20010816

• Regulation of mesangial cell function by vasodilatory signaling molecules.

  Cardiovascular research 20010815

• SCID in Jack Russell terriers: a new animal model of DNA-PKcs deficiency.

  Journal of immunology (Baltimore, Md. : 1950) 20010815

• Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii.

  Journal of molecular biology 20010810

• Acivicin induces apoptosis independently of gamma-glutamyltranspeptidase activity.

  Biochemical and biophysical research communications 20010803

• Inactivation of O(6)-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors.

  International journal of cancer 20010801

• DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling.

  International journal of cancer 20010801

• Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

  Biochemical pharmacology 20010801

• Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.

  The Journal of pharmacology and experimental therapeutics 20010801

• Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex.

  Journal of the American Chemical Society 20010801

• Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.

  Cancer research 20010801

• Determination of the effects of mycophenolic acid on the nucleotide pool of human peripheral blood mononuclear cells in vitro by high-performance liquid chromatography.

  Clinica chimica acta; international journal of clinical chemistry 20010801

• In vitro effects of mycophenolic acid on the nucleotide pool and on the expression of adhesion molecules of human umbilical vein endothelial cells.

  Clinica chimica acta; international journal of clinical chemistry 20010801

• Relationship between dopamine-stimulated phospholipid methylation and the single-carbon folate pathway.

  Journal of neurochemistry 20010801

• Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein.

  Cancer chemotherapy and pharmacology 20010801

• Structural basis for allosteric substrate specificity regulation in anaerobic ribonucleotide reductases.

  Structure (London, England : 1993) 20010801

• [Evaluation of the tonic and phasic effects of endogenous adenosine on the transmitter secretion in the neuromuscular junction].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010801

• Infectious complications of purine analog therapy.

  Current opinion in infectious diseases 20010801

• Multiple cleavage activities of endonuclease V from Thermotoga maritima: recognition and strand nicking mechanism.

  Biochemistry 20010731

• Nucleotide binding domain 1 of the human retinal ABC transporter functions as a general ribonucleotidase.

  Biochemistry 20010727

• Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts.

  Biochemistry 20010727

• Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.

  Biochemistry 20010727

• Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase.

  Biochimica et biophysica acta 20010727

• Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia.

  The New England journal of medicine 20010726

• Photoactivation of DNA thiobases as a potential novel therapeutic option.

  Current biology : CB 20010724

• Diaminopurine-acridine heterodimers for specific recognition of abasic site containing DNA. Influence on the biological activity of the position of the linker on the purine ring.

  Bioorganic & medicinal chemistry letters 20010723

• Nitric oxide inhibits methionine synthase activity in vivo and disrupts carbon flow through the folate pathway.

  The Journal of biological chemistry 20010720

• Molecular genetics of nucleoside transporters in Leishmania and African trypanosomes.

  Biochemical pharmacology 20010715

• Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor?

  Journal of neuroscience research 20010715

• Application of mixed partition-adsorption systems in high-performance liquid chromatography of purines and pyrimidines.

  Journal of chromatography. A 20010713

• A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.

  Biochemistry 20010710

• Misacylation and editing by Escherichia coli valyl-tRNA synthetase: evidence for two tRNA binding sites.

  Biochemistry 20010710

• Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins.

  Biochemistry 20010710

• Purine but not pyrimidine nucleotides support rotation of F(1)-ATPase.

  The Journal of biological chemistry 20010706

• Salmonella-based tumor-targeted cancer therapy: tumor amplified protein expression therapy (TAPET) for diagnostic imaging.

  Journal of controlled release : official journal of the Controlled Release Society 20010706

• Requirement of de novo protein synthesis for aminopterin-induced apoptosis in a mouse myeloma cell line.

  Immunology letters 20010702

• Changes in hippocampal adenosine efflux, ATP levels, and synaptic transmission induced by increased temperature.

  Synapse (New York, N.Y.) 20010701

• Involvement of astrocytes in purine-mediated reparative processes in the brain.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20010701

• Apical P2Y4 purinergic receptor controls K+ secretion by vestibular dark cell epithelium.

  American journal of physiology. Cell physiology 20010701

• Pharmacokinetic studies of 2-amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an oral prodrug for the antiviral agent penciclovir.

  Drug metabolism and disposition: the biological fate of chemicals 20010701

• Purine salvage to adenine nucleotides in different skeletal muscle fiber types.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010701

• Prognostic factors and response to fludarabine therapy in patients with Waldenström macroglobulinemia: results of United States intergroup trial (Southwest Oncology Group S9003).

  Blood 20010701

• Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.

  Nature structural biology 20010701

• Crystallographic studies on damaged DNAs: III. N(4)-methoxycytosine can form both Watson-Crick type and wobbled base pairs in a B-form duplex.

  Journal of biochemistry 20010701

• Release of ATP by a human retinal pigment epithelial cell line: potential for autocrine stimulation through subretinal space.

  The Journal of physiology 20010701

• Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling.

  The Journal of clinical investigation 20010701

• Expression, purification, and characterization of recombinant purine nucleoside phosphorylase from Escherichia coli.

  Protein expression and purification 20010701

• Complete sequencing of mono-deprotonated peptide nucleic acids by sustained off-resonance irradiation collision-induced dissociation.

  Journal of the American Society for Mass Spectrometry 20010701

• Purine N7 groups that are crucial to the interaction of Escherichia coli rnase P RNA with tRNA.

  RNA (New York, N.Y.) 20010701

• trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4-tetrahydrodi- benz[a,j]acridine involvement in dibenz[a,j]acridine DNA adduct formation in mouse skin consistent with Ha-ras mutation patterns in tumors.

  Chemical research in toxicology 20010701

• Effect of nitrogen source in high-concentrate, low-protein beef cattle diets on microbial fermentation studied in vivo and in vitro.

  Journal of animal science 20010701

• [Combination therapy of IFN and ribavirin].

  Nihon rinsho. Japanese journal of clinical medicine 20010701

• Targeting of human Tmolt4 leukemic type II IMP dehydrogenase by cyclic imide related derivatives.

  Archiv der Pharmazie 20010701

• [Pulmonary changes in rheumatoid arthritis].

  Ceskoslovenska patologie 20010701

• Purine receptor agonists protect the genome of plant and animal cells from clastogen damage.

  Bulletin of experimental biology and medicine 20010701

• Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase.

  The Journal of biological chemistry 20010629

• Comparative evaluation of Celsior solution versus Viaspan in a pig liver transplantation model.

  Transplantation 20010627

• Behaviour of inorganic and organic cations in the Debye-Hückel layer of DNA.

  Journal of chromatography. A 20010622

• Slow motion in the CAA*TTG sequence of a DNA decamer duplex studied by NMR.

  Biochemistry 20010619

• Feedback inhibition of amidophosphoribosyltransferase regulates the rate of cell growth via purine nucleotide, DNA, and protein syntheses.

  The Journal of biological chemistry 20010615

• A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.

  FEBS letters 20010615

• Physico-chemical studies on DNA triplexes containing an alternate third strand with a non-nucleotide linker.

  International journal of biological macromolecules 20010612

• Intercalation of the (1R,2S,3R,4S)-N6-[1-(1,2,3,4-tetrahydro-2,3,4-trihydroxybenz[a]anthracenyl)]-2'-deoxyadenosyl adduct in the N-ras codon 61 sequence: DNA sequence effects.

  Biochemistry 20010612

• Molecular genetics and structural biology of human MutT homolog, MTH1.

  Mutation research 20010602

• Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity.

  Protein science : a publication of the Protein Society 20010601

• A phase III, randomized, double-blind, placebo-controlled study of peldesine (BCX-34) cream as topical therapy for cutaneous T-cell lymphoma.

  Journal of the American Academy of Dermatology 20010601

• Ray38p, a homolog of a purine motif triple-helical DNA-binding protein, Stm1p, is a ribosome-associated protein and dissociated from ribosomes prior to the induction of cycloheximide resistance in Candida maltosa.

  Biochemical and biophysical research communications 20010601

• Biogenesis and function of peroxisomes and glycosomes.

  Molecular and biochemical parasitology 20010601

• Involvement of a transformylase enzyme in siderophore synthesis in Pseudomonas aeruginosa.

  Microbiology (Reading, England) 20010601

• Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro.

  Anti-cancer drugs 20010601

• Altered purine nucleotide degradation during exercise in patients with essential hypertension.

  Metabolism: clinical and experimental 20010601

• Characterisation of an ATP diphosphohydrolase (Apyrase, EC 3.6.1.5) activity in Trichomonas vaginalis.

  International journal for parasitology 20010601

• Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent.

  International immunopharmacology 20010601

• Synthesis and properties of triple helix-forming oligodeoxyribonucleotides containing 7-chloro-7-deaza-2'-deoxyguanosine.

  Bioorganic & medicinal chemistry 20010601

• A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA.

  RNA (New York, N.Y.) 20010601

• Application of capillary electrophoresis in the analysis of novel synthetic dideoxynucleoside analogues with potential anti-HIV activity.

  Biomedical chromatography : BMC 20010601

• Prostaglandins and nitric oxide mediate superoxide-induced myocardial contractile dysfunction in isolated rat hearts.

  Journal of molecular and cellular cardiology 20010601

• Origins of life: a route to nanotechnology.

  Bio Systems 20010601

• Diet and medication in the treatment of hyperuricemia in hypertensive patients.

  Arquivos brasileiros de cardiologia 20010601

• Two novel mutations in a purine nucleoside phosphorylase (PNP)-deficient patient.

  Clinical genetics 20010601

• Cardiac sympathetic afferent activation provoked by myocardial ischemia and reperfusion. Mechanisms and reflexes.

  Annals of the New York Academy of Sciences 20010601

• Phase I and pharmacokinetic study of LY309887: a specific inhibitor of purine biosynthesis.

  Cancer chemotherapy and pharmacology 20010601

• Treatment options in Waldenström's macroglobulinaemia: the role of the purine analogues.

  Expert opinion on pharmacotherapy 20010601

• Infectious complications in chronic lymphoid malignancy.

  Current treatment options in oncology 20010601

• Autoimmunity in chronic lymphocytic leukemia.

  Current treatment options in oncology 20010601

• Immunotherapy of chronic lymphocytic leukemia.

  Expert review of anticancer therapy 20010601

• Update on prophylaxis and therapy of infection in patients with chronic lymphocytic leukemia.

  Expert review of anticancer therapy 20010601

• Hairy cell leukemia: treatment prospects.

  Expert review of anticancer therapy 20010601

• Hybridization between oxy-peptide nucleic acids and DNAs: dependence of hybrid stabilities on the chain-lengths, types of base pairs, and the chain directions.

  Journal of the American Chemical Society 20010523

• Molecular design of a new class of spin-labeled ribonucleosides with N-tert-butylaminoxyl radicals.

  The Journal of organic chemistry 20010518

• Gcn2 mediates Gcn4 activation in response to glucose stimulation or UV radiation not via GCN4 translation.

  The Journal of biological chemistry 20010518

• 2'-Ribose-ferrocene oligonucleotides for electronic detection of nucleic acids.

  The Journal of organic chemistry 20010504

• Characterization of nucleoside transport systems in cultured rat epididymal epithelium.

  American journal of physiology. Cell physiology 20010501

• VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent.

  Journal of pharmaceutical sciences 20010501

• Novel treatment strategies in chronic lymphocytic leukemia.

  Current oncology reports 20010501

• Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.

  Molecular pharmacology 20010501

• Structural determinants of adenophostin A activity at inositol trisphosphate receptors.

  Molecular pharmacology 20010501

• Uridine receptor: discovery and its involvement in sleep mechanism.

  Sleep 20010501

• Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.

  Nature structural biology 20010501

• Enhanced activity of the purine nucleotide cycle of the exercising muscle in patients with hyperthyroidism.

  The Journal of clinical endocrinology and metabolism 20010501

• Effects of purine and pyrimidine nucleotides on intracellular Ca2+ in human eosinophils: activation of purinergic P2Y receptors.

  The Journal of allergy and clinical immunology 20010501

• Fragmentation of electrospray-produced oligodeoxynucleotide ions adducted to metal ions.

  Journal of the American Society for Mass Spectrometry 20010501

• 9(R)-[6(R)-hydroxymethyl-1-oxa-4-thiacyclohexan-2-yl]hypoxanthine-water (4/3), a nucleoside analogue.

  Acta crystallographica. Section C, Crystal structure communications 20010501

• Diminished adenosine A1 receptor expression on macrophages in brain and blood of patients with multiple sclerosis.

  Annals of neurology 20010501

• Competence development by Haemophilus influenzae is regulated by the availability of nucleic acid precursors.

  Molecular microbiology 20010501

• Evaluation of the mutagenic and genotoxic activities of anti-hepatitis B analogs of beta-L-adenosine by the Ames test and the Comet assay.

  Antiviral research 20010501

• A possible prebiotic synthesis of purine, adenine, cytosine, and 4(3H)-pyrimidinone from formamide: implications for the origin of life.

  Bioorganic & medicinal chemistry 20010501

• Chemical modification of aryl-1,2,3,6-tetrahydropyridinopyrimidine derivative to discover corticotropin-releasing factor(1) receptor antagonists: aryl-1,2,3,6-tetrahydropyridino-purine, -3H-1,2,3-triazolo[4,5-d)pyrimidine, -purin-8-one, and -7H-pyrrolo[2,3-d]pyrimidine derivatives.

  Bioorganic & medicinal chemistry 20010501

• Does intensive treatment with high dose chlorambucil and prednisone as first line and cladribine as second line influence the survival of the patients with chronic lymphocytic leukemia?

  Leukemia & lymphoma 20010501

• Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide.

  British journal of haematology 20010501

• Population pharmacokinetic modeling and model validation of a spicamycin derivative, KRN5500, in phase 1 study.

  Cancer chemotherapy and pharmacology 20010501

• Neurologic aspects of adenylosuccinate lyase deficiency.

  Journal of child neurology 20010501

• The activities of purine catabolizing enzymes in plasma and bronchial washing fluid in patients with lung cancer and pneumonia.

  Clinical biochemistry 20010501

• gsk disruption leads to guanosine accumulation in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20010501

• Pemetrexed disodium, a novel antifolate with multiple targets.

  The Lancet. Oncology 20010501

• Pdx-1 is required for activation in vivo from a duodenum-specific enhancer.

  The Journal of biological chemistry 20010427

• Lack of catalytic activity of a murine mRNA cytoplasmic serine hydroxymethyltransferase splice variant: evidence against alternative splicing as a regulatory mechanism.

  Biochemistry 20010424

• A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time.

  Biochemistry 20010424

• The beta ' subunit of Escherichia coli RNA polymerase is not required for interaction with initiating nucleotide but is necessary for interaction with rifampicin.

  The Journal of biological chemistry 20010420

• Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study.

  Biochemistry 20010417

• Selective recognition of pyrimidine motif triplexes by a protein encoded by the bacterial transposon Tn7.

  Journal of molecular biology 20010413

• Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.

  Journal of molecular biology 20010413

• Solution conformation of an RNA--DNA hybrid duplex containing a pyrimidine RNA strand and a purine DNA strand.

  International journal of biological macromolecules 20010412

• Effect on urinary bladder function and arterial blood pressure of the activation of putative purine receptors in brainstem areas.

  Autonomic neuroscience : basic & clinical 20010412

• UDP hydrolase activity associated with the porcine liver annexin fraction.

  Biochimica et biophysica acta 20010403

• 15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines.

  Biochemistry 20010403

• The effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of spinal neurones following carrageenan inflammation and peripheral nerve injury.

  British journal of pharmacology 20010401

• Local changes in GC/AT substitution biases and in crossover frequencies on Drosophila chromosomes.

  Molecular biology and evolution 20010401

• Ascorbic acid changes the pattern of purine metabolism during germination of white spruce somatic embryos.

  Tree physiology 20010401

• Functional characterization of a maize purine transporter by expression in Aspergillus nidulans.

  The Plant cell 20010401

• Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2).

  Chemical research in toxicology 20010401

• Analysis of peroxynitrite reactions with guanine, xanthine, and adenine nucleosides by high-pressure liquid chromatography with electrochemical detection: C8-nitration and -oxidation.

  Chemical research in toxicology 20010401

• Microxine, a new cdc2 kinase inhibitor from the Australian marine sponge Microxina species.

  Journal of natural products 20010401

• Determination of purine compounds in carotid artery plaque by liquid chromatography electrospray ionization tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20010401

• Proteome and transcriptome based analysis of Bacillus subtilis cells overproducing an insoluble heterologous protein.

  Applied microbiology and biotechnology 20010401

• Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast.

  Journal of molecular medicine (Berlin, Germany) 20010401

• The analysis of human amniotic fluid using capillary electrophoresis.

  Electrophoresis 20010401

• Tmolt4 leukemic type II isoform of IMP dehydrogenase as a target for 1,2,4-triazolidine-3,5-diones, 1-(1-(3-methylphenyl)ethylidineamino)-4,4-diethyl-3,5-azetidinediones, 3,5-isoxazolidinediones, and 4,4-disubstituted-3,5-pyrazolidinediones.

  Archiv der Pharmazie 20010401

• Extracellular ATP potentiates steroidogenic effect of adrenocorticotropic hormone in bovine adrenocortical fasciculata cells.

  Japanese journal of pharmacology 20010401

• A unique surface membrane anchored purine-salvage enzyme is conserved among a group of primitive eukaryotic human pathogens.

  Molecular and cellular biochemistry 20010401

• Activity of pemetrexed (ALIMTA, multitargeted antifolate, LY231514) in metastatic breast cancer patients previously treated with an anthracycline and a taxane: an interim analysis.

  Clinical breast cancer 20010401

• CyaG, a novel cyanobacterial adenylyl cyclase and a possible ancestor of mammalian guanylyl cyclases.

  The Journal of biological chemistry 20010330

• Activation of glutamate uptake by guanosine in primary astrocyte cultures.

  Neuroreport 20010326

• Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.

  Journal of molecular biology 20010323

• Reflections on the purinergic hypothesis: the Burnstock Festschrift in the millennial year.

  Autonomic neuroscience : basic & clinical 20010323

• 7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties.

  The Journal of biological chemistry 20010316

• Macrochelation, cyclometallation and G-quartet formation: N3- and C8-bound PdII complexes of adenine and guanine.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010316

• Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes.

  Yeast (Chichester, England) 20010315

• Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes.

  Chemico-biological interactions 20010314

• The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.

  Biochemistry 20010306

• Adenosine increases ventilation rate, cardiac performance and haemolymph velocity in the American lobster Homarus americanus.

  The Journal of experimental biology 20010301

• Sugar-modified nucleosides in past 10 years, a review.

  Current medicinal chemistry 20010301

• Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter.

  Biology of reproduction 20010301

• Adenosine deaminase: functional implications and different classes of inhibitors.

  Medicinal research reviews 20010301

• New immunosuppressive drugs: an update.

  Current opinion in urology 20010301

• The protective effect of acadesine on lung ischemia-reperfusion injury.

  Anesthesia and analgesia 20010301

• UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency.

  Biochimica et biophysica acta 20010301

• Cell cycle in the fucus zygote parallels a somatic cell cycle but displays a unique translational regulation of cyclin-dependent kinases.

  The Plant cell 20010301

• Gas-phase hydrogen/deuterium exchange of positively charged mononucleotides by use of Fourier-transform ion cyclotron resonance mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20010301

• Active intestinal absorption of nucleosides by Na+-dependent transport across the brush border membrane in cows.

  Journal of dairy science 20010301

• Nucleoside transporters of parasitic protozoa.

  Trends in parasitology 20010301

• The spectrum of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency. Clinical experience based on 22 patients from 18 Spanish families.

  Medicine 20010301

• Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships.

  Bioorganic & medicinal chemistry 20010301

• Effective treatment with rituximab in a patient with refractory prolymphocytoid transformed B-chronic lymphocytic leukemia and Evans syndrome.

  Annals of hematology 20010301

• The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers.

  Journal of hypertension 20010301

• Intramolecular stacking interactions in ternary copper(II) complexes formed with 2,2'-bipyridine or 1,10-phenanthroline and 9-(4-phosphonobutyl)adenine (dPMEA), the carba relative of the antiviral nucleotide analogue 9.

  Journal of inorganic biochemistry 20010301

• Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110.

  Bioscience, biotechnology, and biochemistry 20010301

• An extended structural signature for the tRNA anticodon loop.

  RNA (New York, N.Y.) 20010301

• Immunostimulant oxidized beta-glucan conjugates.

  International immunopharmacology 20010301

• Role of the Escherichia coli and human DNA glycosylases that remove 5-formyluracil from DNA in the prevention of mutations.

  Journal of radiation research 20010301

• HF-STEX and RASSCF calculations on nitrogen K-shell X-ray absorption of purine base and its derivative.

  Journal of synchrotron radiation 20010301

• DAPD (Emory University/Triangle Pharmaceuticals/Abbott Laboratories).

  Current opinion in investigational drugs (London, England : 2000) 20010301

• Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene.

  Molecular and cellular endocrinology 20010227

• Metal ion-directed cooperative triple helix formation of glutamic acid--oligonucleotide conjugate.

  Journal of the American Chemical Society 20010227

• Eosinophil peroxidase catalyzes bromination of free nucleosides and double-stranded DNA.

  Biochemistry 20010220

• Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme.

  Biochemistry 20010220

• Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.

  Biochimica et biophysica acta 20010216

• In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

  Biochemical pharmacology 20010215

• A kinetic study on the interaction of deprotonated purine radical cations with amino acids and model peptides.

  Biophysical chemistry 20010215

• A quantitative model for allosteric control of purine reduction by murine ribonucleotide reductase.

  Biochemistry 20010213

• Determination of urinary methylated purine pattern by high-performance liquid chromatography.

  Journal of chromatography. B, Biomedical sciences and applications 20010210

• Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation.

  Blood 20010201

• A purF mutant of Mycobacterium smegmatis has impaired survival during oxygen-starved stationary phase.

  Microbiology (Reading, England) 20010201

• Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole.

  American journal of physiology. Heart and circulatory physiology 20010201

• Extracellular ATP induces a distorted maturation of dendritic cells and inhibits their capacity to initiate Th1 responses.

  Journal of immunology (Baltimore, Md. : 1950) 20010201

• Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.

  Molecular pharmacology 20010201

• A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans.

  Molecular pharmacology 20010201

• The evolution of ribonucleotide reduction revisited.

  Trends in biochemical sciences 20010201

• The folate cycle and disease in humans.

  Kidney international. Supplement 20010201

• Annexins as nucleotide-binding proteins: facts and speculations.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20010201

• Structure-function relationships in UCP1, UCP2 and chimeras: EPR analysis and retinoic acid activation of UCP2.

  European journal of biochemistry 20010201

• Assessment of Leishmania promastigote growth in vitro by means of nucleoside hydrolase activity determination.

  Parasitology research 20010201

• Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010201

• A novel assay for determination of diadenosine polyphosphates in human platelets: studies in normotensive subjects and in patients with essential hypertension.

  Journal of hypertension 20010201

• Sequential fluorescence in situ hybridization analyses for trisomy 12 in chronic leukemic B-cell disorders.

  Haematologica 20010201

• Effect of furosemide on renal excretion of oxypurinol and purine bases.

  Metabolism: clinical and experimental 20010201

• [Pharmacological profiles of mycophenolate mofetil (CellCept), a new immunosuppressive agent].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010201

• Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010201

• Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.

  Critical care medicine 20010201

• Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile.

  Chemical research in toxicology 20010201

• Uric acid mediates photodynamic inactivation of caprine alpha-2-macroglobulin.

  Free radical research 20010201

• Regulation of hisHF transcription of Aspergillus nidulans by adenine and amino acid limitation.

  Fungal genetics and biology : FG & B 20010201

• Disturbance of purine nucleotide metabolism: a possible early key event in development of intestinal damage induced by chemotherapy.

  Digestive diseases and sciences 20010201

• Blood purine and energy status in rats with colitis.

  Digestive diseases and sciences 20010201

• Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, nitric oxide donors, and purine derivatives.

  Antioxidants & redox signaling 20010201

• Candida tropicalis and Penicillium marneffei mixed fungaemia in a patient with Waldenström's macroglobulinaemia.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010201

• Intra- and intermolecular triplex DNA formation in the murine c-myb proto-oncogene promoter are inhibited by mithramycin.

  Biological chemistry 20010201

• Second primary tumors and immune phenomena after fludarabine or 2-chloro-2'-deoxyadenosine treatment.

  Leukemia & lymphoma 20010201

• Cladribine in the treatment of chronic lymphocytic leukemia.

  Leukemia & lymphoma 20010201

• Cytogenetic analysis oxidative damage in lymphocytes of Parkinson's disease patients.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20010201

• The current state of extracorporeal haemorheotherapy: from haemodilution via cascadefiltration to rheohaemapheresis.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20010201

• Cangrelor AstraZeneca.

  Current opinion in investigational drugs (London, England : 2000) 20010201

• A new experimental system for study on adaptive mutations.

  Science in China. Series C, Life sciences 20010201

• Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.

  Biochemistry 20010130

• Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence.

  Biochemistry 20010130

• Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

  The Journal of biological chemistry 20010126

• Role of conserved nucleotides in building the 16 S rRNA binding site for ribosomal protein S15.

  Journal of molecular biology 20010126

• Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after treatment with oxonic acid and allopurinol.

  Life sciences 20010126

• The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status.

  Mutation research 20010125

• Non-oxidative mechanisms are responsible for the induction of mutagenesis by reduction of Cr(VI) with cysteine: role of ternary DNA adducts in Cr(III)-dependent mutagenesis.

  Biochemistry 20010116

• Binding site of Fe3+ at purine of ATP as studied by NMR.

  Journal of inorganic biochemistry 20010115

• The RihA, RihB, and RihC ribonucleoside hydrolases of Escherichia coli. Substrate specificity, gene expression, and regulation.

  The Journal of biological chemistry 20010112

• Interaction of Escherichia coli purine nucleoside phosphorylase (PNP) with the cationic and zwitterionic forms of the fluorescent substrate N(7)-methylguanosine.

  Biochimica et biophysica acta 20010112

• Xanthine dehydrogenase from Pseudomonas putida 86: specificity, oxidation-reduction potentials of its redox-active centers, and first EPR characterization.

  Biochimica et biophysica acta 20010112

• Cloning of a novel isoform of the mouse NBMPR-sensitive equilibrative nucleoside transporter (ENT1) lacking a putative phosphorylation site.

  Gene 20010110

• The characteristics of nucleobase transport and metabolism by the perfused sheep choroid plexus.

  Brain research 20010105

• The main products of the low molecular mass fraction in the venom of the spider Latrodectus menavodi.

  Toxicon : official journal of the International Society on Toxinology 20010101

• Properties of native P2X receptors in rat trigeminal mesencephalic nucleus neurones: lack of correlation with known, heterologously expressed P2X receptors.

  Neuropharmacology 20010101

• Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells.

  Molecular pharmacology 20010101

• The role of uric acid in protection against peroxynitrite-mediated pathology.

  Medical hypotheses 20010101

• Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion.

  Acta crystallographica. Section D, Biological crystallography 20010101

• Metabolic fate of extracellular NAD in human skin fibroblasts.

  Journal of cellular biochemistry 20010101

• Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides.

  Journal of the American Society for Mass Spectrometry 20010101

• Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells.

  Endocrinology 20010101

• Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

• Effect of the tropical forage calliandra on microbial protein synthesis and ecology in the rumen.

  Journal of applied microbiology 20010101

• Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR.

  Carcinogenesis 20010101

• Characterization of a triplex DNA-binding protein encoded by an alternative reading frame of loricrin.

  European journal of biochemistry 20010101

• Unexpectedly high incidence of hypoplastic/aplastic foci in bone marrow biopsies of hairy cell leukemia patients in remission following 2-chlorodeoxyadenosine therapy.

  European journal of haematology 20010101

• Use of molecular beacons to verify that the serine hydroxymethyltransferase pseudogene SHMT-ps1 is unique to the order Primates.

  Genome biology 20010101

• Structure-activity relationships for a collection of structurally diverse inhibitors of purine nucleoside phosphorylase.

  Chemical & pharmaceutical bulletin 20010101

• 6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia.

  Leukemia 20010101

• beta-Amyloid protein induces the formation of purine dimers in cellular DNA.

  Journal of cellular biochemistry 20010101

• Prebiotic synthesis of nucleotides.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20010101

• Genome-wide analysis of protein-DNA interactions in living cells.

  Genome biology 20010101

• 2-chlorodeoxyadenosine (cladribine) in the treatment of hairy cell leukemia.

  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010101

• Azathioprine therapy for patients with systemic lupus erythematosus.

  Lupus 20010101

• Treatment of systemic lupus erythematosus with mycophenolate mofetil.

  Lupus 20010101

• Comparative sequence analysis of plasmids pME2001 and pME2200 of methanothermobacter marburgensis strains Marburg and ZH3.

  Plasmid 20010101

• A concomitant ATP-depleting strategy markedly enhances anticancer agent activity.

  Apoptosis : an international journal on programmed cell death 20010101

• Photolithographic synthesis of high-density oligonucleotide arrays.

  Methods in molecular biology (Clifton, N.J.) 20010101

• New aspects on the pathogenesis, diagnostic procedures, and therapeutic management of chronic lymphocytic leukemia.

  International journal of hematology 20010101

• The nitrilase superfamily: classification, structure and function.

  Genome biology 20010101

• Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

  Molecular membrane biology 20010101

• Complex regulation of nucleoside transporter expression in epithelial and immune system cells.

  Molecular membrane biology 20010101

• Gouty arthritis: not just a big toe problem.

  Geriatric nursing (New York, N.Y.) 20010101

• Purine analogs as CDK enzyme inhibitory agents: a survey and QSAR analysis.

  Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20010101

• [Purine biosynthesis de novo in the retina: evolutionary aspects].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20010101

• Uncoupling proteins in mitochondria of plants and some microorganisms.

  Acta biochimica Polonica 20010101

• Adenine toxicity and transport in the moderately halophilic eubacterium Halomonas elongata.

  Journal of basic microbiology 20010101

• A systematic overview of chemotherapy effects in indolent non-Hodgkin's lymphoma.

  Acta oncologica (Stockholm, Sweden) 20010101

• A systematic overview of chemotherapy effects in B-cell chronic lymphocytic leukaemia.

  Acta oncologica (Stockholm, Sweden) 20010101

• Proteins, nucleic acids and genetic codes.

  Rivista di biologia 20010101

• [Post-radiation changes in kinetic parameters of purine-catabolizing enzymes in rat blood serum after combined action of external and internal irradiation caused by 137Cs].

  Radiatsionnaia biologiia, radioecologiia 20010101

• Angiotensin-induced enhancement of excitatory junction potentials evoked by periarteriolar nerve stimulation and vasoconstriction in rat mesenteric arteries are both mediated by the angiotensin AT1 receptor.

  Pharmacology 20010101

• [Use of plasmapheresis for correction of metabolic disorders in patients with surgical sepsis].

  Anesteziologiia i reanimatologiia 20010101

• [Adenine reutilization as a cause of increased ATP concentration in erythrocytes of patients with chronic renal failure].

  Polskie Archiwum Medycyny Wewnetrznej 20010101

• [Urine fibrinolytic activity as an indicator of kidney damage in uric acid metabolic imbalance].

  Terapevticheskii arkhiv 20010101

• Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management.

  Drug safety 20010101

• Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors.

  The oncologist 20010101

• Gene targeting via triple-helix formation.

  Progress in nucleic acid research and molecular biology 20010101

• Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells.

  Progress in nucleic acid research and molecular biology 20010101

• [Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101

• DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes.

  Progress in nucleic acid research and molecular biology 20010101

• Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage.

  Progress in nucleic acid research and molecular biology 20010101

• Autoimmune thrombocytopenia associated with the first cycle of fludarabine therapy in the treatment of relapsed non-Hodgkin's lymphoma.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101

• Altered intracellular purine nucleotides in gamma-irradiated red blood cell concentrates.

  Vox sanguinis 20010101

• Potent in vitro anticancer activities of ring-expanded ('fat') nucleosides containing the imidazo[4,5-e][1,3]diazepine ring system.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis and in vitro antiviral activity evaluation of 9-(2-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)adenine derivatives.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis and antiviral activity of novel exomethylene cyclopropyl nucleosides.

  Nucleosides, nucleotides & nucleic acids 20010101

• The design and synthesis of purine inhibitors of CDK2. III.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis of 8-amino and 8-substituted amino derivatives of acyclic purine nucleoside and nucleotide analogs. Alkylation of 8-substituted purine bases.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis and evaluation of antiviral activity of higher homologues of xylo-carbocyclic nucleosides.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis and base pairing properties of 9-deazapurine N7-nucleosides in oligonucleotide duplexes and triplexes.

  Nucleosides, nucleotides & nucleic acids 20010101

• Large-scale manufacturing of all four 2'-deoxynucleosides via novel strategies including a chemo-enzymatic process.

  Nucleosides, nucleotides & nucleic acids 20010101

• Ribose modified nucleosides and nucleotides as ligands for purine receptors.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis and antiviral activity of D- and L-2'-azido-2',3'-dideoxy-4'-thiopyrimidine and purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis and biological activity of 4'-C-hydroxymethyl-2'-fluoro-D-arabinofuranosylpurine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20010101

• Cell imaging and morphology: application to studies of inherited purine metabolic disorders.

  Pharmacology & therapeutics 20010101

• [Disorders of purine metabolism and the antioxidant system in obstetrical-gynecologic sepsis].

  Anesteziologiia i reanimatologiia 20010101

• Immunoreactivity to P2X(6) receptors in the rat hypothalamo-neurohypophysial system: an ultrastructural study with extravidin and colloidal gold-silver labelling.

  Neuroscience 20010101

• Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol.

  Genome biology 20010101

• An atypical case of primary renal tubular hypokalaemic metabolic alkalosis with chronic tophaceous gout.

  Clinical rheumatology 20010101

• Purine and pyrimidine nucleoside analogs.

  Cancer chemotherapy and biological response modifiers 20010101

• Alveolar epithelial type II cell: defender of the alveolus revisited.

  Respiratory research 20010101

• The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis.

  Respiratory research 20010101

• Pharmacology of airway afferent nerve activity.

  Respiratory research 20010101

• Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affect gene expression in Saccharomyces cerevisiae.

  BMC molecular biology 20010101

• Xanthine oxidase catalyzes the synthesis of retinoic acid.

  Journal of enzyme inhibition 20010101

• Fulminant hepatic failure secondary to adenovirus following fludarabine-based chemotherapy for non-Hodgkin's lymphoma.

  Leukemia & lymphoma 20010101

• Perturbations in the impact of mutational activity on Vlambda genes in systemic lupus erythematosus.

  Arthritis research 20010101

• Sequence-specific DNA cleavage by dipeptides disubstituted with chlorambucil and 2,6-dimethoxyhydroquinone-3-mercaptoacetic acid.

  Bioconjugate chemistry 20010101

• Prediction of co-regulated genes in Bacillus subtilis on the basis of upstream elements conserved across three closely related species.

  Genome biology 20010101

• Optimality of the genetic code with respect to protein stability and amino-acid frequencies.

  Genome biology 20010101

• Frequencies and relative levels of clustered damages in DNA exposed to gamma rays in radioquenching vs. nonradioquenching conditions.

  Environmental and molecular mutagenesis 20010101

• Effect of 5-aminoimidazole-4-carboxamide riboside (AICA-r) on isolated thoracic aorta responses in streptozotocin-diabetic rats.

  Journal of basic and clinical physiology and pharmacology 20010101

• Base excision repair processing of radiation-induced clustered DNA lesions.

  Radiation protection dosimetry 20010101

• [Structural organization of the human genome: distribution of nucleotides, Alu-repeats and exons in chromosomes 21 and 22].

  Molekuliarnaia biologiia 20010101

• Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus.

  Clinical rheumatology 20010101

• Clustered DNA damages induced by high and low LET radiation, including heavy ions.

  Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 20010101

• Effect of level and origin of rumen degradable nitrogen on rumen microbial growth and nitrogen utilisation efficiency of animals fed maize silage at maintenance.

  Reproduction, nutrition, development 20010101

• Hyperuricemia and gout in thyroid endocrine disorders.

  Clinical and experimental rheumatology 20010101

• The mitochondrial uncoupling protein UCP1: a gated pore.

  IUBMB life 20010101

• The role of non-myeloablative conditioning in allowing engraftment of allogeneic hematopoietic cells for correction of genetic disorders and for immunotherapy of leukemia.

  Annals of transplantation 20010101

• Complete nucleotide sequence and the genome organization of Patchouli mild mosaic virus RNA1.

  Intervirology 20010101

• [Molecular genetic features of Vibrio cholerae classica strains, that caused the Asiatic cholera epidemic in Russian in 1942].

  Molekuliarnaia genetika, mikrobiologiia i virusologiia 20010101

• A theoretical investigation on the effect of remote amino groups in hydrogen bonding of nucleic acids.

  Biopolymers 20010101

• Antileukemic activity of synthetic daunomycinone derivatives bearing modifications in the glycosidic moiety.

  Anticancer research 20010101

• The role of ring D in the antitumour antibiotic streptonigrin: metal complexation, DNA binding and topoisomerase inhibition by ABC ring analogues of streptonigrin.

  Anti-cancer drug design 20010101

• [Specific interactions of isoguanine with the neutral and deprotonated carboxylic group of amino acids: results of model quantum chemical calculations].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101

• A purine-sensitive mechanism regulates the molecular program for axon growth.

  Restorative neurology and neuroscience 20010101

• Effect of N fertilisation rate, energy supplementation and supplementation strategy on efficiency of N utilisation in the sheep rumen.

  Archiv fur Tierernahrung 20010101

• Purine nucleotide metabolism in cultured neurons and astroglia from HPRT-deficient knockout mice.

  The Italian journal of biochemistry 20010101

• Biochemical and metabolic peculiarities of some parasites availing as targets for therapy.

  Le Journal medical libanais. The Lebanese medical journal 20010101

• Fate of prebiotic adenine.

  Astrobiology 20010101

• Effect of temperature on the adsorption of adenine.

  Astrobiology 20010101

• Efforts toward creating unnatural base pairs for an expanded genetic code.

  Nucleic acids research. Supplement (2001) 20010101

• Adduct formation between oxanine and amine derivatives.

  Nucleic acids research. Supplement (2001) 20010101

• Synthesis and properties of a new class of nucleosides with spin source.

  Nucleic acids research. Supplement (2001) 20010101

• Synthetic study of guanofosfocin. Synthesis of 8-(mannopyranosyloxy)inosine derivative.

  Nucleic acids research. Supplement (2001) 20010101

• X-ray analyses of DNA dodecamers containing 2'-deoxy-5-formyluridine.

  Nucleic acids research. Supplement (2001) 20010101

• Promotion of duplex and triplex DNA formation by polycation comb-type copolymers.

  Methods in molecular medicine 20010101

• Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro.

  Biochemical and biophysical research communications 20000714

• Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.

  Biochemical pharmacology 19951109

• 2-amino-9-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-6-substituted-9H-purines: synthesis and anti-HIV activity.

  Bioorganic & medicinal chemistry 19950401

• A STUDY OF THE CROSS-REACTIVITY OF ANTIPURIN-6-OYL SERUM WITH DEOXYRIBONUCLEIC ACID (DNA).

  The Journal of experimental medicine 19650101