120075-24-3 | Fmoc-d-arg(mtr)-oh

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$30.00	$21.00
5g	95%	in stock	$110.00	$77.00
25g	95%	in stock	$454.00	$318.00

Description

• Catalog Number: AA33810
• Chemical Name: Fmoc-d-arg(mtr)-oh
• CAS Number: 120075-24-3
• Molecular Formula: C31H36N4O7S
• Molecular Weight: 608.7051
• MDL Number: MFCD00065616
• SMILES: COc1cc(C)c(c(c1C)C)S(=O)(=O)NC(=N)NCCC[C@H](C(=O)O)NC(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 1070
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 43
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 13
• XLogP3: 4.4

Upstream Synthesis Route

Fmoc-D-Arg(Mtr)-OH is a valuable building block in chemical synthesis, particularly in the field of peptide synthesis. This amino acid derivative is commonly used in solid-phase peptide synthesis to introduce D-arginine residues with protected side chains. The Fmoc (9-fluorenylmethyloxycarbonyl) group serves as a temporary protecting group for the amino group of D-arginine, allowing for selective manipulation of the side chain while maintaining the integrity of the peptide backbone.In addition, the Mtr (4-methoxy-2,3,6-trimethylbenzenesulfonyl) protecting group is used to shield the guanidine group of D-arginine, providing increased stability during synthesis and preventing unwanted side reactions. This dual protection strategy ensures the successful incorporation of D-arginine in peptide sequences, enabling the precise design and construction of complex peptides with specific biological activities.Overall, Fmoc-D-Arg(Mtr)-OH plays a crucial role in the synthesis of bioactive peptides, pharmaceuticals, and peptide mimetics, offering chemists a versatile tool for enhancing peptide properties and functionality in various chemical and biological applications.