1203-68-5 | 2-Phenylbenzaldehyde

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$12.00	$9.00
5g	98%	in stock	$22.00	$16.00
10g	98%	in stock	$27.00	$19.00
25g	98%	in stock	$67.00	$47.00

Description

• Catalog Number: AB43824
• Chemical Name: 2-Phenylbenzaldehyde
• CAS Number: 1203-68-5
• Molecular Formula: C13H10O
• Molecular Weight: 182.2179
• MDL Number: MFCD01740431
• SMILES: O=Cc1ccccc1c1ccccc1

Computed Properties

• Complexity: 182
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 3.4

Upstream Synthesis Route

2-Biphenylcarboxaldehyde, also known as biphenyl-2-carbaldehyde, is a versatile compound widely used in chemical synthesis. Its unique structure, consisting of two phenyl rings attached to a carbonyl group, makes it a valuable building block in the creation of various organic compounds.In organic synthesis, 2-Biphenylcarboxaldehyde serves as a key intermediate in the production of pharmaceuticals, agrochemicals, and dyes. Its aromatic nature and reactivity allow for functional group manipulation, enabling chemists to introduce specific structural motifs into target molecules. This compound is particularly valuable in the formation of heterocycles, which are essential components in many biologically active compounds.Additionally, 2-Biphenylcarboxaldehyde can be utilized in the preparation of ligands for transition metal catalysis, facilitating the creation of complex molecules with high efficiency and selectivity. Its ability to participate in various types of organic reactions, such as Grignard reactions, Friedel-Crafts acylation, and Wittig reactions, makes it a versatile tool in the hands of synthetic chemists.Overall, 2-Biphenylcarboxaldehyde plays a crucial role in modern chemical synthesis, offering a wide range of applications and contributing to the development of novel compounds with valuable properties.

Literature

• Enantioselective synthesis of fluorene derivatives by chiral N-triflyl phosphoramide catalyzed double Friedel-Crafts alkylation reaction.

  Organic & biomolecular chemistry 20120428

• Potent histone deacetylase inhibitors: N-hydroxybenzamides with antitumor activities.

  Bioorganic & medicinal chemistry 20040815

• ERbeta ligands. Part 2: Synthesis and structure-activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives.

  Bioorganic & medicinal chemistry 20040515

• Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis.

  Journal of medicinal chemistry 20040115

• Highly enhanced enantioselectivity in the memory of chirality via acyliminium ions.

  Organic letters 20020530