120369-25-7 | N-Benzyl L-Valinamide

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$201.00	$141.00
1g	97%	in stock	$510.00	$357.00
5g	97%	in stock	$1,535.00	$1,074.00
10g	97%	in stock	$2,266.00	$1,586.00

Description

• Catalog Number: AD74471
• Chemical Name: N-Benzyl L-Valinamide
• CAS Number: 120369-25-7
• Molecular Formula: C12H18N2O
• Molecular Weight: 206.2841
• MDL Number: MFCD09724562
• SMILES: N[C@H](C(=O)NCc1ccccc1)C(C)C

Computed Properties

• Complexity: 198
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 1.5

Literature

• Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain-attenuating properties.

  Journal of medicinal chemistry 20111013

• Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities.

  Journal of medicinal chemistry 20110714

• Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors.

  Journal of medicinal chemistry 20000224