121-45-9 | Trimethyl phosphite

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$25.00	$18.00
25g	97%	in stock	$47.00	$33.00
250g	97%	in stock	$148.00	$104.00

Description

• Catalog Number: AB80067
• Chemical Name: Trimethyl phosphite
• CAS Number: 121-45-9
• Molecular Formula: C3H9O3P
• Molecular Weight: 124.0755
• MDL Number: MFCD00008350
• SMILES: COP(OC)OC
• NSC Number: 6513

Computed Properties

• Complexity: 31.7
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• XLogP3: 0.1

Upstream Synthesis Route

Trimethyl phosphite, a versatile organophosphorus compound, serves as a valuable reagent in chemical synthesis. Its primary application lies in its utility as a phosphitylating agent, facilitating the formation of phosphorus-carbon bonds through the Staudinger reaction. Trimethyl phosphite is widely employed in the production of phosphonates, phosphinates, phosphonamidates, and phosphoramidites, key intermediates in pharmaceutically active compounds and agrochemicals. Additionally, it finds use as a coupling reagent in peptide synthesis and as a stabilizer in polymerization reactions. Its compatibility with a variety of functional groups and ease of handling make it a go-to choice in synthetic organic chemistry.

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