1211542-19-6 | 5-Hydroxy-3-methylpicolinic acid

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Description

• Catalog Number: BA14870
• Chemical Name: 5-Hydroxy-3-methylpicolinic acid
• CAS Number: 1211542-19-6
• Molecular Formula: C7H7NO3
• Molecular Weight: 153.1354
• SMILES: Oc1cnc(c(c1)C)C(=O)O

Upstream Synthesis Route

5-Hydroxy-3-methylpyridine-2-carboxylic acid, also known as HMPA, is a versatile compound utilized in chemical synthesis for its unique properties. In organic chemistry, HMPA serves as a polar aprotic solvent, enabling efficient dissolution of various organic compounds. Its high polarity and low nucleophilicity make it ideal for promoting reactions such as Grignard additions, metal halogen exchange, and Wittig reactions. Additionally, HMPA can act as a hydrogen bonding catalyst, facilitating reactions that involve the formation of hydrogen bonds between reactants. This compound's utility extends to the synthesis of pharmaceuticals, agrochemicals, and fine chemicals, where its solvation and catalytic effects play a crucial role in achieving high yields and selectivity.