1213059-76-7 | (2S)-2-Amino-2-[4-chloro-3-(trifluoromethyl)phenyl]ethan-1-ol

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$378.00	$264.00
1g	97%	in stock	$978.00	$684.00

Description

• Catalog Number: AE65359
• Chemical Name: (2S)-2-Amino-2-[4-chloro-3-(trifluoromethyl)phenyl]ethan-1-ol
• CAS Number: 1213059-76-7
• Molecular Formula: C9H9ClF3NO
• Molecular Weight: 239.6221
• MDL Number: MFCD09415670
• SMILES: OC[C@H](c1ccc(c(c1)C(F)(F)F)Cl)N

Computed Properties

• Complexity: 212
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.6

Upstream Synthesis Route

(S)-2-Amino-2-(4-chloro-3-(trifluoromethyl)phenyl)ethanol is a valuable chiral building block in chemical synthesis, particularly in the pharmaceutical industry. This compound is utilized as a key intermediate in the synthesis of various biologically active molecules and pharmaceutical drugs. Its chirality, or specific three-dimensional arrangement of atoms, plays a critical role in the creation of enantiopure compounds with enhanced biological activity and reduced side effects. In asymmetric synthesis, (S)-2-Amino-2-(4-chloro-3-(trifluoromethyl)phenyl)ethanol serves as a starting material for the preparation of chiral ligands, catalysts, and drug candidates through various strategic transformations such as acylation, alkylation, or cyclization reactions. Its unique structure containing both an amine and alcohol functional group allows for versatile derivatization and incorporation into complex molecular architectures. The high chemical purity and stereochemical integrity of this compound make it a sought-after reagent for the construction of structurally diverse and pharmacologically relevant compounds in medicinal chemistry and drug discovery.