1214344-68-9 | 2-Fluoro-5-(trifluoromethyl)pyrimidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$105.00	$74.00
1g	98%	in stock	$241.00	$169.00
5g	98%	in stock	$898.00	$629.00
10g	98%	in stock	$1,535.00	$1,074.00

Description

• Catalog Number: AE64116
• Chemical Name: 2-Fluoro-5-(trifluoromethyl)pyrimidine
• CAS Number: 1214344-68-9
• Molecular Formula: C5H2F4N2
• Molecular Weight: 166.0764
• MDL Number: MFCD13185662
• SMILES: Fc1ncc(cn1)C(F)(F)F

Computed Properties

• Complexity: 127
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 6
• XLogP3: 1.5

Upstream Synthesis Route

2-Fluoro-5-(trifluoromethyl)pyrimidine, also known as $name$, is a versatile compound widely utilized in chemical synthesis. With its unique structural properties, this compound plays a crucial role in various organic reactions and transformations.In the realm of chemical synthesis, 2-fluoro-5-(trifluoromethyl)pyrimidine serves as a valuable building block for the creation of complex organic molecules. Its fluorine and trifluoromethyl groups confer distinctive reactivity and can be harnessed for diverse functionalization strategies.One key application of 2-fluoro-5-(trifluoromethyl)pyrimidine is in the synthesis of pharmaceuticals and agrochemicals. The presence of the fluorine atom enhances the biological activity of the resulting compounds, making it an attractive choice for medicinal chemistry projects. Additionally, the trifluoromethyl group provides steric hindrance and lipophilicity that can influence the physicochemical properties of the target molecules.Furthermore, this compound can participate in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings, enabling the construction of carbon-carbon and carbon-nitrogen bonds. Its use in various transformations, such as halogenation, arylation, and alkylation, showcases its utility as a versatile synthetic building block.Overall, the application of 2-fluoro-5-(trifluoromethyl)pyrimidine in chemical synthesis underscores its importance as a valuable tool for the development of novel compounds with diverse functionalities and applications in the fields of pharmaceuticals, materials science, and beyond.