1214377-57-7 | 5-Bromo-2-cyano-3-(trifluoromethyl)pyridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$43.00	$30.00
1g	98%	in stock	$60.00	$42.00
5g	98%	in stock	$202.00	$141.00
25g	98%	in stock	$960.00	$672.00

Description

• Catalog Number: AA52863
• Chemical Name: 5-Bromo-2-cyano-3-(trifluoromethyl)pyridine
• CAS Number: 1214377-57-7
• Molecular Formula: C7H2BrF3N2
• Molecular Weight: 251.0034
• MDL Number: MFCD13185358
• SMILES: N#Cc1ncc(cc1C(F)(F)F)Br

Computed Properties

• Complexity: 232
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 5
• XLogP3: 2.5

Upstream Synthesis Route

5-Bromo-2-cyano-3-(trifluoromethyl)pyridine is a versatile building block in chemical synthesis due to its unique structural features and reactivity. This compound serves as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and functional materials. Its bromo and cyano functional groups are valuable for introducing diversely substituted pyridine derivatives through cross-coupling reactions. The trifluoromethyl group enhances the compound's lipophilicity and electron-withdrawing nature, making it a potent precursor for the synthesis of bioactive molecules. Additionally, the presence of the bromine atom enables further functionalization through various nucleophilic substitution reactions, facilitating the creation of novel compounds with enhanced biological activities. Overall, 5-Bromo-2-cyano-3-(trifluoromethyl)pyridine is a crucial component in the toolbox of synthetic chemists for the construction of complex molecules with significant pharmacological or material science applications.