121649-18-1 | 5-(4-Fluorophenyl)-3H-1,3,4-oxadiazol-2-one

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$155.00	$108.00
5g	98%	in stock	$473.00	$331.00
10g	98%	in stock	$775.00	$543.00
25g	98%	in stock	$1,536.00	$1,075.00

Description

• Catalog Number: AA53585
• Chemical Name: 5-(4-Fluorophenyl)-3H-1,3,4-oxadiazol-2-one
• CAS Number: 121649-18-1
• Molecular Formula: C8H5FN2O2
• Molecular Weight: 180.1359
• MDL Number: MFCD06373475
• SMILES: Fc1ccc(cc1)c1n[nH]c(=O)o1

Computed Properties

• Complexity: 247
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.5

Upstream Synthesis Route

5-(4-Fluorophenyl)-1,3,4-oxadiazol-2(3H)-one is a versatile compound widely used in chemical synthesis as a key building block for various organic reactions. This compound serves as a valuable intermediate in the preparation of biologically active molecules and pharmaceuticals due to its unique structure and reactivity. In organic synthesis, it is commonly employed as a precursor for the synthesis of heterocyclic compounds, potential drug candidates, and agrochemicals. Additionally, 5-(4-Fluorophenyl)-1,3,4-oxadiazol-2(3H)-one plays a crucial role in the development of new materials and functional polymers with desirable properties. Its utilization in chemical synthesis highlights its significance in the creation of diverse molecular architectures for advancing research in medicinal chemistry, materials science, and related fields.

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101