1217500-59-8 | 1-BOC-6-Bromo-indole-2-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$79.00	$55.00
1g	97%	in stock	$84.00	$59.00
5g	97%	in stock	$328.00	$230.00
25g	97%	in stock	$1,396.00	$978.00

Description

• Catalog Number: AA53845
• Chemical Name: 1-BOC-6-Bromo-indole-2-boronic acid
• CAS Number: 1217500-59-8
• Molecular Formula: C13H15BBrNO4
• Molecular Weight: 339.9775
• MDL Number: MFCD15143453
• SMILES: Brc1ccc2c(c1)n(C(=O)OC(C)(C)C)c(c2)B(O)O

Computed Properties

• Complexity: 374
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3

Upstream Synthesis Route

1-Boc-6-Bromo-indole-2-boronic acid is a versatile compound widely utilized in organic chemical synthesis. This boronic acid derivative is known for its valuable application as a key building block in the synthesis of various pharmaceuticals and biologically active molecules. The presence of the Boc (tert-butoxycarbonyl) protecting group offers protection to sensitive functional groups during chemical reactions, allowing for selective manipulations and control over reaction pathways. In particular, the bromo substituent on the indole ring enables cross-coupling reactions with suitable partners to introduce additional functional groups or complex structures into the molecule. This compound's boronic acid moiety further serves as a crucial component for Suzuki-Miyaura coupling reactions, facilitating the formation of carbon-carbon bonds in the synthesis of diverse organic compounds. Its strategic positioning of functional groups makes 1-Boc-6-Bromo-indole-2-boronic acid a valuable tool for synthetic chemists seeking to design and construct complex molecular architectures efficiently and selectively.