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AA54311

1218-34-4 | N-Acetyl-L-tryptophan

Packsize Purity Availability Price Discounted Price    Quantity
5g 98% in stock $13.00 $9.00 -   +
25g 98% in stock $20.00 $14.00 -   +
500g 98% in stock $251.00 $176.00 -   +

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Description
Catalog Number: AA54311
Chemical Name: N-Acetyl-L-tryptophan
CAS Number: 1218-34-4
Molecular Formula: C13H14N2O3
Molecular Weight: 246.26185999999998
MDL Number: MFCD00065976
SMILES: CC(=O)N[C@H](C(=O)O)Cc1c[nH]c2c1cccc2

 

Computed Properties
Complexity: 332  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 18  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 4  
XLogP3: 1.1  

 

 

Upstream Synthesis Route 
  • Ac-Trp-OH, known chemically as N-Acetyl-L-tryptophan, is a valuable compound in chemical synthesis, particularly in the field of peptide synthesis. This amino acid derivative serves as a critical building block for creating peptides with specific sequences and properties. Ac-Trp-OH is commonly used in solid-phase peptide synthesis (SPPS) as a protected amino acid, where the N-acetyl group provides stability and protection during the peptide assembly process.In addition to its role in peptide synthesis, Ac-Trp-OH is also utilized in medicinal chemistry for the development of peptide-based drugs and pharmaceuticals. Its unique properties, including its aromatic side chain and ability to participate in hydrogen bonding interactions, make it a versatile tool in designing bioactive peptides with enhanced potency and selectivity.Furthermore, Ac-Trp-OH can be employed in the study of protein structure and function, as well as in the synthesis of peptide mimetics and peptidomimetics. These molecules can mimic the structure and activity of peptides while offering improved stability and pharmacokinetic properties, making them promising candidates for drug discovery and development.Overall, Ac-Trp-OH plays a crucial role in the synthesis and design of peptides and peptide-derived compounds with diverse applications in biomedical research, drug development, and chemical biology.
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