1218790-83-0 | 3-((Tetrahydrofuran-2-yl)methylcarbamoyl)phenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$44.00	$31.00
250mg	98%	in stock	$72.00	$51.00
1g	98%	in stock	$126.00	$88.00
5g	98%	in stock	$605.00	$423.00

Description

• Catalog Number: AA54602
• Chemical Name: 3-((Tetrahydrofuran-2-yl)methylcarbamoyl)phenylboronic acid
• CAS Number: 1218790-83-0
• Molecular Formula: C12H16BNO4
• Molecular Weight: 249.0707
• MDL Number: MFCD12546614
• SMILES: O=C(c1cccc(c1)B(O)O)NCC1CCCO1

Computed Properties

• Complexity: 287
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 4
• Undefined Atom Stereocenter Count: 1

Upstream Synthesis Route

The compound (3-(((Tetrahydrofuran-2-yl)methyl)carbamoyl)phenyl)boronic acid is commonly utilized in chemical synthesis as a versatile building block for the creation of various organic molecules. This compound is highly valued for its ability to serve as a key component in the construction of complex structures due to its unique reactivity and functional groups.In organic synthesis, (3-(((Tetrahydrofuran-2-yl)methyl)carbamoyl)phenyl)boronic acid is often employed as a coupling partner in Suzuki-Miyaura cross-coupling reactions. This reaction enables the formation of carbon-carbon bonds by coupling an aryl or heteroaryl boronic acid with an organic halide or pseudohalide in the presence of a palladium catalyst. By utilizing (3-(((Tetrahydrofuran-2-yl)methyl)carbamoyl)phenyl)boronic acid in this reaction, chemists can selectively introduce the phenylboronic acid group into the target molecule, allowing for the precise modification and functionalization of organic compounds.Furthermore, (3-(((Tetrahydrofuran-2-yl)methyl)carbamoyl)phenyl)boronic acid can also participate in other important transformations such as halogenation, arylation, and Suzuki-Miyaura cross-coupling with various electrophiles. Its ability to undergo such diverse reactions makes it a valuable tool in the hands of synthetic chemists seeking to access a wide range of complex molecules with specific functionalities.In summary, the application of (3-(((Tetrahydrofuran-2-yl)methyl)carbamoyl)phenyl)boronic acid in chemical synthesis offers a strategic approach for the construction of structurally intricate organic molecules, making it a crucial component in the arsenal of synthetic chemists striving to develop novel compounds with tailored properties.