1220039-43-9 | 2-(Pyrimidin-2-yl)acetamide

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$126.00	$88.00
1g	95%	in stock	$356.00	$249.00
5g	95%	in stock	$1,365.00	$956.00
10g	95%	in stock	$2,656.00	$1,859.00
25g	95%	in stock	$4,786.00	$3,350.00

Description

• Catalog Number: AA54993
• Chemical Name: 2-(Pyrimidin-2-yl)acetamide
• CAS Number: 1220039-43-9
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.1393
• MDL Number: MFCD15475001
• SMILES: NC(=O)Cc1ncccn1

Computed Properties

• Complexity: 120
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: -0.9

Upstream Synthesis Route

2-(Pyrimidin-2-yl)acetamide is a versatile compound widely used in chemical synthesis for its ability to serve as a building block in the creation of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure, combining a pyrimidine ring with an acetamide functional group, makes it a valuable intermediate in the synthesis of complex organic molecules.In chemical synthesis, 2-(Pyrimidin-2-yl)acetamide can undergo various reactions such as acylation, alkylation, and cyclization to introduce different chemical moieties and create diverse compounds with specific properties. It can be utilized in the synthesis of heterocyclic compounds, which are important in drug discovery and development due to their biological activities.Furthermore, 2-(Pyrimidin-2-yl)acetamide can be employed as a ligand in coordination chemistry, forming complexes with metal ions for catalytic purposes or as building blocks in the construction of coordination polymers. Its flexibility in participating in different chemical transformations makes it a valuable tool in organic synthesis for creating novel compounds with potential applications in various industries.

Literature

• Stereoselectivity and regioselectivity in nucleophilic ring opening in derivatives of 3-phenylisoxazolo[2,3-a]pyrimidine. Unpredicted dimerization and ring transformation. Syntheses of derivatives of pyrimidinylmethylamine, pyrimidinylmethylamino acid amides, and alpha-amino-2-pyrimidinylacetamides.

  The Journal of organic chemistry 20040723