1220219-43-1 | 3,4-Difluoro-5-hydroxyphenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$89.00	$62.00
250mg	98%	in stock	$115.00	$80.00
1g	98%	in stock	$330.00	$231.00
5g	98%	in stock	$1,131.00	$792.00
10g	98%	in stock	$1,878.00	$1,315.00

Description

• Catalog Number: AA55063
• Chemical Name: 3,4-Difluoro-5-hydroxyphenylboronic acid, pinacol ester
• CAS Number: 1220219-43-1
• Molecular Formula: C12H15BF2O3
• Molecular Weight: 256.0535
• MDL Number: MFCD16996287
• SMILES: Oc1cc(cc(c1F)F)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 308
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1

Upstream Synthesis Route

The compound 2,3-Difluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is utilized as a versatile building block in chemical synthesis. Due to the presence of the difluoro motif and the boronate functionality, this compound is commonly employed in the synthesis of pharmaceuticals, agrochemicals, and materials. It serves as a key intermediate in various organic reactions, such as Suzuki-Miyaura cross-coupling, palladium-catalyzed C-C bond formation, and heterocycle construction. The unique combination of fluorine atoms and boron moiety imparts specific properties to the molecule, making it an important tool for medicinal chemists and synthetic organic chemists in their quest to design and develop novel compounds with enhanced biological activities and material properties.