1220219-63-5 | 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$63.00	$44.00
250mg	97%	in stock	$100.00	$70.00
1g	97%	in stock	$249.00	$175.00
5g	97%	in stock	$758.00	$531.00
10g	97%	in stock	$1,317.00	$922.00
25g	97%	in stock	$2,623.00	$1,836.00

Description

• Catalog Number: AI14444
• Chemical Name: 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile
• CAS Number: 1220219-63-5
• Molecular Formula: C12H14BClN2O2
• Molecular Weight: 264.51576
• MDL Number: MFCD16995199
• SMILES: N#Cc1ncc(cc1Cl)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 364
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1

Upstream Synthesis Route

3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile is a valuable chemical reagent in organic synthesis, specifically known for its utility in various chemical reactions. This compound serves as a versatile building block in the construction of complex organic molecules due to its unique structural features and reactivity.In chemical synthesis, 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile is commonly employed as a key intermediate in cross-coupling reactions, such as Suzuki-Miyaura coupling and Stille coupling. These reactions enable the formation of carbon-carbon and carbon-heteroatom bonds, facilitating the synthesis of pharmaceutically relevant compounds, agrochemicals, and functional materials.Furthermore, the presence of the dioxaborolane moiety in this compound imparts enhanced stability and compatibility in various synthetic protocols. This stability allows for mild reaction conditions and improved selectivity, making 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile a preferred choice for chemists seeking efficient and reliable methods for constructing complex molecular architectures.Overall, this compound plays a crucial role in modern organic synthesis by enabling the efficient creation of diverse chemical structures with high precision and control, making it an indispensable tool for synthetic chemists across different research fields.