122350-52-1 | Fmoc-glu-obzl

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$12.00	$9.00
5g	97%	in stock	$16.00	$12.00
10g	97%	in stock	$20.00	$14.00
25g	97%	in stock	$48.00	$34.00

Description

• Catalog Number: AA55724
• Chemical Name: Fmoc-glu-obzl
• CAS Number: 122350-52-1
• Molecular Formula: C27H25NO6
• Molecular Weight: 459.4905
• MDL Number: MFCD00080272
• SMILES: OC(=O)CC[C@@H](C(=O)OCc1ccccc1)NC(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 683
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 11
• XLogP3: 4.4

Upstream Synthesis Route

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 1-(phenylmethyl) ester is a key compound utilized in chemical synthesis as a versatile building block. Its unique structure allows for the incorporation of both the fluorenylmethoxycarbonyl (Fmoc) protecting group and the phenylmethyl ester group, which play critical roles in peptide synthesis.In peptide chemistry, Fmoc is commonly used to protect the amine group of amino acids during solid-phase peptide synthesis. This protecting group can be selectively removed under mild basic conditions, enabling the stepwise assembly of peptides with high purity and yield. The presence of the phenylmethyl ester group further enhances the stability of the peptide during synthesis and purification processes.Moreover, the compatibility of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 1-(phenylmethyl) ester with various coupling reagents and reaction conditions makes it an invaluable tool for the synthesis of complex peptides and peptide derivatives. Its efficient deprotection and cleavage properties make it a preferred choice for peptide chemists seeking to streamline synthetic strategies and enhance overall synthetic efficiency.