1224844-38-5 | Ink-128

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$33.00	$23.00
2mg	98%	in stock	$50.00	$35.00
5mg	98%	in stock	$57.00	$40.00
10mg	98%	in stock	$81.00	$57.00
50mg	98%	in stock	$136.00	$95.00
100mg	98%	in stock	$177.00	$124.00
250mg	98%	in stock	$355.00	$249.00
1g	98%	in stock	$859.00	$601.00

Description

• Catalog Number: AA55910
• Chemical Name: Ink-128
• CAS Number: 1224844-38-5
• Molecular Formula: C15H15N7O
• Molecular Weight: 309.3259
• MDL Number: MFCD22124893
• SMILES: Nc1oc2c(n1)cc(cc2)c1nn(c2c1c(N)ncn2)C(C)C

Computed Properties

• Complexity: 436
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.7

Literature

• Dual mTOR inhibitor MLN0128 suppresses Merkel cell carcinoma (MCC) xenograft tumor growth.

  Oncotarget 20160209

• Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120501

• The translational landscape of mTOR signalling steers cancer initiation and metastasis.

  Nature 20120222

• ATP-competitive inhibitors of mTOR: an update.

  Current medicinal chemistry 20110101

• mTOR Mediated Anti-Cancer Drug Discovery.

  Drug discovery today. Therapeutic strategies 20090101