1227515-52-7 | (3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-methanol

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$45.00	$32.00
500mg	98%	in stock	$90.00	$63.00
1g	98%	in stock	$114.00	$80.00
5g	98%	in stock	$458.00	$321.00
10g	98%	in stock	$826.00	$579.00

Description

• Catalog Number: AA24810
• Chemical Name: (3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-methanol
• CAS Number: 1227515-52-7
• Molecular Formula: C7H5F4NO
• Molecular Weight: 195.1143
• MDL Number: MFCD11848347
• SMILES: OCc1ncc(cc1F)C(F)(F)F

Computed Properties

• Complexity: 172
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1

Upstream Synthesis Route

The compound (3-fluoro-5-(trifluoromethyl)pyridine-2-yl)methanol is a versatile chemical intermediate that finds widespread application in organic synthesis. It can serve as a building block for the preparation of various pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure, featuring both a fluorine and a pyridine moiety, lends itself to diverse chemical manipulations.One significant application of (3-fluoro-5-(trifluoromethyl)pyridine-2-yl)methanol is in the preparation of fluorinated organic compounds. The presence of fluorine atoms in the molecule imparts distinct properties such as increased lipophilicity, metabolic stability, and biological activity, making it an attractive starting material for the synthesis of fluorinated drug candidates.Furthermore, the pyridine ring in the molecule can act as a directing group in transition metal-catalyzed coupling reactions. This functionality enables selective functionalization at specific positions within the molecule, facilitating the construction of complex organic frameworks with precision.Overall, the strategic placement of fluorine and pyridine functionalities in (3-fluoro-5-(trifluoromethyl)pyridine-2-yl)methanol makes it a valuable tool in the hands of synthetic chemists for the efficient assembly of diverse molecular architectures with potential applications in the pharmaceutical, agricultural, and materials science industries.