1227594-84-4 | Methyl 2-hydroxy-5-(trifluoromethyl)pyridine-4-carboxylate

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$330.00	$231.00
5g	98%	in stock	$1,131.00	$792.00

Description

• Catalog Number: AI14888
• Chemical Name: Methyl 2-hydroxy-5-(trifluoromethyl)pyridine-4-carboxylate
• CAS Number: 1227594-84-4
• Molecular Formula: C8H6F3NO3
• Molecular Weight: 221.1333
• MDL Number: MFCD16611630
• SMILES: COC(=O)c1cc(O)ncc1C(F)(F)F

Computed Properties

• Complexity: 368
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 0.2

Upstream Synthesis Route

Methyl 1,2-dihydro-2-oxo-5-(trifluoromethyl)-4-pyridinecarboxylate serves as a versatile building block in chemical synthesis due to its unique structural properties. This compound is widely utilized in the pharmaceutical industry for the synthesis of novel drug candidates and active pharmaceutical ingredients. With its trifluoromethyl group, Methyl 1,2-dihydro-2-oxo-5-(trifluoromethyl)-4-pyridinecarboxylate contributes to enhancing the biological activity and metabolic stability of the synthesized compounds. In addition, its pyridine ring provides a pharmacophore that can be further modified to fine-tune the desired properties of the target molecules. In organic chemistry, this compound is employed as a key intermediate in the synthesis of various heterocyclic compounds, making it a valuable tool for accessing diverse chemical structures with potential biological significance.