122841-12-7 | Cefoselis sulfate

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$34.00	$24.00
5mg	≥98%	in stock	$88.00	$62.00
10mg	95%	in stock	$153.00	$107.00
25mg	≥98%	in stock	$286.00	$200.00
50mg	≥98%	in stock	$437.00	$306.00
100mg	≥98%	in stock	$723.00	$506.00

Description

• Catalog Number: AA25180
• Chemical Name: Cefoselis sulfate
• CAS Number: 122841-12-7
• Molecular Formula: C19H24N8O10S3
• Molecular Weight: 620.6365
• MDL Number: MFCD01940015
• SMILES: OS(=O)(=O)O.OCCn1c(=N)ccn1CC1=C(C(=O)O)N2[C@H](SC1)[C@@H](C2=O)NC(=O)/C(=N\OC)/c1csc(n1)N

Computed Properties

• Complexity: 1100
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 40
• Hydrogen Bond Acceptor Count: 17
• Hydrogen Bond Donor Count: 7
• Rotatable Bond Count: 9

Literature

• Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.

  Biochemical pharmacology 20051001

• Cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release.

  Journal of neural transmission (Vienna, Austria : 1996) 20041201

• Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptors.

  Pharmacology, biochemistry, and behavior 20021201

• Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.

  Oral microbiology and immunology 20021001

• The beta-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABA(A) receptors.

  British journal of pharmacology 20020101

• Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats.

  Biological & pharmaceutical bulletin 20010901