1255580-76-7 | 4-Quinazolinamine, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$62.00	$44.00
5mg	98%	in stock	$151.00	$106.00
10mg	98%	in stock	$270.00	$189.00
50mg	98%	in stock	$818.00	$573.00
100mg	98%	in stock	$1,408.00	$985.00

Description

• Catalog Number: AA30720
• Chemical Name: 4-Quinazolinamine, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-
• CAS Number: 1255580-76-7
• Molecular Formula: C30H47N5O2
• Molecular Weight: 509.7265
• MDL Number: MFCD17215972
• SMILES: COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN1CCCC1)C1CCCCC1

Computed Properties

• Complexity: 660
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 37
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 10
• XLogP3: 6.3

Literature

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  ACS medicinal chemistry letters 20140213

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  PloS one 20140101

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  Journal of medicinal chemistry 20131114

• Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death.

  Cell death & disease 20130201

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  European journal of medicinal chemistry 20121001

• Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.

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  Nature chemical biology 20110710