1262618-39-2 | 6-(4-(Trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine

Packsize	Purity	Availability	Price	Discounted Price
1mg	98+%	in stock	$14.00	$10.00
5mg	98+%	in stock	$34.00	$24.00
10mg	98+%	in stock	$50.00	$35.00
25mg	98+%	in stock	$83.00	$58.00
100mg	≥98%	in stock	$306.00	$215.00
250mg	95%	in stock	$333.00	$233.00
1g	95%	in stock	$778.00	$544.00

Description

• Catalog Number: AA36641
• Chemical Name: 6-(4-(Trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
• CAS Number: 1262618-39-2
• Molecular Formula: C14H7F6N3O
• Molecular Weight: 347.2153
• MDL Number: MFCD28385879
• SMILES: FC(Oc1ccc(cc1)c1ccc2n(c1)c(nn2)C(F)(F)F)(F)F

Computed Properties

• Complexity: 435
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 2
• XLogP3: 4.9

Literature

• Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.

  British journal of pharmacology 20180601

• Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazine.

  Bioorganic & medicinal chemistry letters 20160701

• Hydrolyzable and nonhydrolyzable 3,4-dichloroaniline-humus complexes and their respective rates of biodegradation.

  Journal of agricultural and food chemistry 19760101