126456-43-7 | (1S,2R)-(-)-Cis-1-amino-2-indanol

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$6.00	$5.00
10g	98%	in stock	$12.00	$9.00
25g	95%	in stock	$17.00	$12.00
100g	98%	in stock	$68.00	$48.00
500g	98%	in stock	$334.00	$234.00

Description

• Catalog Number: AD29948
• Chemical Name: (1S,2R)-(-)-Cis-1-amino-2-indanol
• CAS Number: 126456-43-7
• Molecular Formula: C9H11NO
• Molecular Weight: 149.1897
• MDL Number: MFCD00216655
• SMILES: N[C@@H]1[C@H](O)Cc2c1cccc2

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: 0.2

Literature

• Enantioselective acylation of 1,2- and 1,3-diols catalyzed by aminophosphinite derivatives of (1S,2R)-1-amino-2-indanol.

  Organic letters 20120203

• Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and omega-transaminase.

  Biotechnology and bioengineering 20060205

• Potent P1' biphenylmethyl substituted aggrecanase inhibitors.

  Bioorganic & medicinal chemistry letters 20020107

• Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors.

  Journal of medicinal chemistry 20011011