127-47-9 | Vitamin A Acetate

Packsize	Purity	Availability	Price	Discounted Price
100mg	2800000%	in stock	$11.00	$8.00
1g	2800000%	in stock	$13.00	$9.00
10g	2800000%	in stock	$27.00	$19.00
25g	2800000%	in stock	$32.00	$22.00
100g	2800000%	in stock	$96.00	$68.00
500g	2800000%	in stock	$336.00	$236.00

Description

• Catalog Number: AA41951
• Chemical Name: Vitamin A Acetate
• CAS Number: 127-47-9
• Molecular Formula: C22H32O2
• Molecular Weight: 328.4883
• MDL Number: MFCD00019413
• SMILES: CC(=O)OC/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)C)C

Computed Properties

• Complexity: 596
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 4
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• XLogP3: 6.3

Upstream Synthesis Route

Retinol acetate, a derivative of vitamin A, serves as a valuable tool in chemical synthesis due to its versatile applications. In organic synthesis, Retinol acetate can act as a precursor or reagent in the preparation of various compounds. Its reactivity allows for the modification of chemical structures, leading to the creation of new molecules with desired properties. Retinol acetate's presence can facilitate the formation of complex organic molecules through processes such as esterification, acylation, and reduction reactions. Additionally, Retinol acetate can be utilized in the synthesis of pharmaceuticals, cosmetics, and other specialty chemicals where its unique properties play a crucial role in the development of innovative products. Its ability to undergo diverse chemical transformations makes Retinol acetate an indispensable component in the realm of chemical synthesis.

Literature

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  International journal of cosmetic science 20120801

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  Physical review. E, Statistical, nonlinear, and soft matter physics 20110501

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  International journal of pharmaceutics 20110214

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  Investigative ophthalmology & visual science 20090901

• Preparation, in vitro and in vivo evaluation of solid-state self-nanoemulsifying drug delivery system (SNEDDS) of vitamin A acetate.

  Journal of drug targeting 20090701

• Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.

  Human molecular genetics 20090615

• Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

  The Journal of biological chemistry 20090529

• Plasma turnover of 3,4-didehydroretinol (vitamin A2) increases in vitamin A-deficient rats fed low versus high dietary fat.

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• Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands.

  Analytical biochemistry 20090115

• Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.

  Investigative ophthalmology & visual science 20090101

• Simultaneous determination of benzophenone-3, retinol and retinyl acetate in pig ear skin layers by high-performance liquid chromatography.

  Biomedical chromatography : BMC 20081001

• New type of microfabricated carbon electrodes for high-performance liquid chromatography--amperometric detection of fat-soluble vitamins and antioxidants.

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  International journal of dermatology 20071101

• Interactions of human serum albumin with retinoic acid, retinal and retinyl acetate.

  Biochemical pharmacology 20070315

• Novel retinoid targets in the mouse limb during organogenesis.

  Toxicological sciences : an official journal of the Society of Toxicology 20061101

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  Journal of chromatography. A 20060728

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  Radiation research 20060501

• Retinoid receptor antagonists alter the pattern of apoptosis in organogenesis stage mouse limbs.

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• Extra-hepatic vitamin A concentrations in captive Rhesus (Macaca mulatta) and Marmoset (Callithrix jacchus) monkeys fed excess vitamin A.

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• Dehydration reaction of hydroxenin monoacetate in carbon tetrachloride and an aliphatic alcohol under ultrasound irradiation.

  Ultrasonics sonochemistry 20050101

• The analysis of the zero-order and the second derivative spectra of retinol acetate, tocopherol acetate and coenzyme Q10 and estimation of their analytical usefulness for their simultaneous determination in synthetic mixtures and pharmaceuticals.

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• Transport across liquid membranes containing vitamin A (retinol acetate).

  Journal of colloid and interface science 20040315

• Tumouricidal activity of gilthead seabream (Sparus aurata L.) natural cytotoxic cells: the role played in vitro and in vivo by retinol acetate.

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  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20030101

• Articular cartilage degradation and de-differentiation of chondrocytes by the systemic administration of retinyl acetate-ectopic production of osteoblast stimulating factor-1 by chondrocytes in mice.

  Osteoarthritis and cartilage 20021201

• The action of a dietary retinoid on gene expression and cancer induction in electron-irradiated rat skin.

  Journal of radiation research 20021201

• Changes in some innate defence parameters of seabream (Sparus aurata L.) induced by retinol acetate.

  Fish & shellfish immunology 20021001

• Dual isotope test for assessing beta-carotene cleavage to vitamin A in humans.

  European journal of nutrition 20020801

• Production of lipospheres as carriers for bioactive compounds.

  Biomaterials 20020601

• Increased antibody production by retinoids is related to the fusion partner of human hybridomas.

  Bioscience, biotechnology, and biochemistry 20020101

• Hydrogen peroxide-induced inhibition of vasomotor activity: evaluation of single and combined treatments with vitamin A and insulin in streptozotocin-diabetic rats.

  International journal of experimental diabetes research 20020101

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  Cell and tissue research 20011201

• Impaired vitamin A-mediated mucosal IgA response in IL-5 receptor-knockout mice.

  Biochemical and biophysical research communications 20010713

• Determination of retinoids in human serum, tocopherol and retinyl acetate in pharmaceuticals by RP-LC with electrochemical detection.

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• The effects of some antioxidant vitamin- and trace element-supplemented diets on activities of SOD, CAT, GSH-Px and LPO levels in chicken tissues.

  Cell biochemistry and function 20010601

• On-line supercritical fluid extraction/enzymatic hydrolysis of vitamin a esters: a new simplified approach for the determination of vitamins a and e in food.

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• Co-carcinogenic effect of retinyl acetate on forestomach carcinogenesis of male F344 rats induced with butylated hydroxyanisole.

  Japanese journal of cancer research : Gann 19880301

• Effects of BHA, d-alpha-tocopherol and retinol acetate on TCDD-mediated changes in lipid peroxidation, glutathione peroxidase activity and survival.

  Xenobiotica; the fate of foreign compounds in biological systems 19840701

• Virucidal activity of retinal.

  Antimicrobial agents and chemotherapy 19790901

• Retinyl acetate prophylaxis in cancer of the urinary bladder.

  Investigative urology 19790301