13063-04-2 | Nitidine Chloride

Packsize	Purity	Availability	Price	Discounted Price
10mg	95%	in stock	$46.00	$33.00
25mg	95%	in stock	$78.00	$55.00
50mg	95%	in stock	$130.00	$91.00

Description

• Catalog Number: AA39626
• Chemical Name: Nitidine Chloride
• CAS Number: 13063-04-2
• Molecular Formula: C21H18ClNO4
• Molecular Weight: 383.8249
• MDL Number: MFCD01659688
• SMILES: COc1cc2c[n+](C)c3c(c2cc1OC)ccc1c3cc2OCOc2c1.[Cl-]
• NSC Number: 146397

Computed Properties

• Complexity: 516
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2

Literature

• Development and validation of an LC-ESI-MS/MS method for the determination of nitidine chloride in rat plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120301

• Biological activities of nitidine, a potential anti-malarial lead compound.

  Malaria journal 20120101

• Nitidine Chloride inhibits breast cancer cells migration and invasion by suppressing c-Src/FAK associated signaling pathway.

  Cancer letters 20111227

• [Study on the alkaloids from the stem of Zanthoxylum dissitum].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110401

• Formal synthesis of nitidine and NK109 via palladium-catalyzed domino direct arylation/N-arylation of aryl triflates.

  Organic letters 20110318

• Distinct G-quadruplex structures of human telomeric DNA formed by the induction of sanguinarine and nitidine under salt-deficient condition.

  Fitoterapia 20101201

• Tumor-selective cytotoxicity of benzo[c]phenanthridine derivatives from Toddalia asiatica Lam.

  Cancer chemotherapy and pharmacology 20100301

• Gold(I)-catalyzed tandem reactions initiated by hydroamination of alkynyl carbamates: application to the synthesis of nitidine.

  The Journal of organic chemistry 20091204

• [Studies on pharmacokinetics of nitidine chloride in rabbits].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601

• DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine.

  Bioorganic & medicinal chemistry 20060815

• Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine.

  Bioorganic & medicinal chemistry 20040715

• Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia.

  Journal of natural products 20040701

• Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents.

  Bioorganic & medicinal chemistry 20030417

• Alkaloids, amides and antispasmodic activity of Zanthoxylum hyemale.

  Planta medica 20020601

• [Determination of nitidine in different parts of Zanthoxylum nitidum].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010901

• Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells.

  Antimicrobial agents and chemotherapy 19991201

• The role of the iminium bond in the inhibition of reverse transcriptase by quaternary benzophenanthridines.

  The Journal of pharmacy and pharmacology 19981101

• Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

  Journal of natural products 19910101