131-57-7 | 2-Hydroxy-4-methoxybenzophenone

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$15.00	$10.00
5g	98%	in stock	$16.00	$11.00
25g	98%	in stock	$19.00	$13.00
100g	98%	in stock	$28.00	$19.00
500g	98%	in stock	$95.00	$66.00

Description

• Catalog Number: AB62319
• Chemical Name: 2-Hydroxy-4-methoxybenzophenone
• CAS Number: 131-57-7
• Molecular Formula: C14H12O3
• Molecular Weight: 228.24328
• MDL Number: MFCD00008387
• SMILES: COc1ccc(c(c1)O)C(=O)c1ccccc1

Computed Properties

• Complexity: 258
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 3.6

Literature

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  The British journal of dermatology 20060201

• Polarographic determination of sunscreen agents in cosmetic products in micellar media.

  Talanta 20060115

• Evaluation of the photostability of different UV filter combinations in a sunscreen.

  International journal of pharmaceutics 20060113

• Influence of complexation with cyclodextrins on photo-induced free radical production by the common sunscreen agents octyl-dimethylaminobenzoate and octyl-methoxycinnamate.

  Die Pharmazie 20060101

• Preparation and characterization of oxybenzone-loaded gelatin microspheres for enhancement of sunscreening efficacy.

  Drug delivery 20060101

• Separation via flotation, spectrophotometric speciation, and determination of vanadium(IV) in wastes of power stations.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051101

• In vivo bioassay-guided fractionation of marine sediment extracts from the Southern California Bight, USA, for estrogenic activity.

  Environmental toxicology and chemistry 20051101

• Additive estrogenic effects of mixtures of frequently used UV filters on pS2-gene transcription in MCF-7 cells.

  Toxicology and applied pharmacology 20051015

• Quantification of urinary conjugates of bisphenol A, 2,5-dichlorophenol, and 2-hydroxy-4-methoxybenzophenone in humans by online solid phase extraction-high performance liquid chromatography-tandem mass spectrometry.

  Analytical and bioanalytical chemistry 20051001

• Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20050901

• Photoallergic and allergic reaction to 2-hydroxy-4-methoxybenzophenone (sunscreen) and allergy to cetyl alcohol in cosmetic cream.

  Contact dermatitis 20050901

• Influence of anatomical site and topical formulation on skin penetration of sunscreens.

  Therapeutics and clinical risk management 20050901

• Simultaneous analysis of insect repellent DEET, sunscreen oxybenzone and five relevant metabolites by reversed-phase HPLC with UV detection: application to an in vivo study in a piglet model.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805

• [Estrogenic activity of ultraviolet absorbers and the related compounds].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050801

• Assay of common sunscreen agents in suncare products by high-performance liquid chromatography on a cyanopropyl-bonded silica column.

  Journal of pharmaceutical and biomedical analysis 20050615

• The effect of packaging materials on the stability of sunscreen emulsions.

  International journal of pharmaceutics 20050613

• In vitro evaluation of concurrent use of commercially available insect repellent and sunscreen preparations.

  The British journal of dermatology 20050601

• Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks.

  Journal of toxicology and environmental health. Part A 20050227

• Occurrence of some organic UV filters in wastewater, in surface waters, and in fish from Swiss Lakes.

  Environmental science & technology 20050215

• Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays.

  Toxicological sciences : an official journal of the Society of Toxicology 20050201

• Unexpected photolysis of the sunscreen octinoxate in the presence of the sunscreen avobenzone.

  Photochemistry and photobiology 20050101

• Sunscreen penetration of human skin and related keratinocyte toxicity after topical application.

  Skin pharmacology and physiology 20050101

• Sunscreens - which and what for?

  Skin pharmacology and physiology 20050101

• Fading of artificial hair color and its prevention by photofilters.

  Journal of cosmetic science 20050101

• Effects of estradiol, benzophenone-2 and benzophenone-3 on the expression pattern of the estrogen receptors (ER) alpha and beta, the estrogen receptor-related receptor 1 (ERR1) and the aryl hydrocarbon receptor (AhR) in adult ovariectomized rats.

  Toxicology 20041201

• Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans.

  The Journal of investigative dermatology 20040701

• Recrystallization in different sunscreen formulations after cutaneous application.

  Journal of cosmetic dermatology 20040701

• [First derivative spetrophotometric direct determination of 2-hydroxy-4-methoxybenzo phenone in polyester resin by computer assistant].

  Guang pu xue yu guang pu fen xi = Guang pu 20040601

• Occurrence of UV filter compounds from sunscreens in surface waters: regional mass balance in two Swiss lakes.

  Chemosphere 20040501

• In-vitro permeation of the insect repellent N,N-diethyl-m-toluamide (DEET) and the sunscreen oxybenzone.

  The Journal of pharmacy and pharmacology 20040501

• Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425

• Contact and photocontact allergy to ketoprofen. The Belgian experience.

  Contact dermatitis 20040401

• Active ingredients in sunscreens act as topical penetration enhancers for the herbicide 2,4-dichlorophenoxyacetic acid.

  Toxicology and applied pharmacology 20040315

• In vitro estrogenicity of resin composites.

  Journal of dental research 20040301

• Golmaenone, a new diketopiperazine alkaloid from the marine-derived fungus Aspergillus sp.

  Chemical & pharmaceutical bulletin 20040301

• Polymeric nanoparticles composed of fatty acids and polyvinylalcohol for topical application of sunscreens.

  The Journal of pharmacy and pharmacology 20040301

• Effect of oxybenzone on PGE2-production in vitro and on plaque and gingivitis in vivo.

  Journal of clinical periodontology 20040201

• Influence of cyclodextrin complexation on the in vivo photoprotective effects of oxybenzone.

  Drug development and industrial pharmacy 20040101

• Microbial transformation of terreusinone, an ultraviolet-A (UV-A) protecting dipyrroloquinone, by Streptomyces sp.

  Chemical & pharmaceutical bulletin 20031201

• Facial erythema as a result of benzophenone allergy.

  Journal of the American Academy of Dermatology 20031101

• Non-invasive in vivo determination of UVA efficacy of sunscreens using diffuse reflectance spectroscopy.

  Photodermatology, photoimmunology & photomedicine 20030801

• UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay.

  Toxicological sciences : an official journal of the Society of Toxicology 20030701

• North American Contact Dermatitis Group patch-test results, 1998 to 2000.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030601

• Determination of butyl methoxydibenzoylmethane, benzophenone-3, octyl dimethyl PABA and octyl methoxycinnamate in lipsticks.

  International journal of cosmetic science 20030601

• TiO2-promoted mineralization of organic sunscreens in water suspension and sodium dodecyl sulfate micelles.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030501

• Contact urticaria, allergic contact dermatitis, and photoallergic contact dermatitis from oxybenzone.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030301

• Skin penetration and sun protection factor of five UV filters: effect of the vehicle.

  Skin pharmacology and applied skin physiology 20030101

• An in vitro systematic spectroscopic examination of the photostabilities of a random set of commercial sunscreen lotions and their chemical UVB/UVA active agents.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021201

• Percutaneous absorption of benzophenone-3, a common component of topical sunscreens.

  Clinical and experimental dermatology 20021101

• [Photocontact dermatitis due to ketoprofen and photosensitization to tetrachlorosalicylanide and to Fenticlor(R)].

  Annales de dermatologie et de venereologie 20021001

• Influence of hydroxypropyl-beta-cyclodextrin on the transdermal permeation and skin accumulation of oxybenzone.

  Drug development and industrial pharmacy 20021001

• Gas chromatographic determination of 2-hydroxy-4-methoxybenzophenone and octyldimethyl-p-aminobenzoic acid sunscreen agents in swimming pool and bathing waters by solid-phase microextraction.

  Journal of chromatography. A 20020823

• The development of an improved carrier system for sunscreen formulations based on crystalline lipid nanoparticles.

  International journal of pharmaceutics 20020821

• Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration.

  Journal of controlled release : official journal of the Controlled Release Society 20020617

• [Cross-reaction potentials of ketoprofen].

  Orvosi hetilap 20020512

• Photosensitive dermatitis due to sunscreen allergy in a child.

  The Australasian journal of dermatology 20020501

• Benzophenone-3: rapid prediction and evaluation using non-invasive methods of in vivo human penetration.

  Journal of pharmaceutical and biomedical analysis 20020401

• 2-Acetylindan-1,3-dione and its Cu(2+) and Zn(2+) complexes as promising sunscreen agents.

  International journal of cosmetic science 20020401

• Metabolism of 2-hydroxy-4-methoxybenzophenone in isolated rat hepatocytes and xenoestrogenic effects of its metabolites on MCF-7 human breast cancer cells.

  Chemico-biological interactions 20020220

• Influence of Transcutol CG on the skin accumulation and transdermal permeation of ultraviolet absorbers.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020101

• A new model using liposomes that allow to distinguish between absorption and oxidative properties of sunscreens.

  Photochemistry and photobiology 20020101

• Severe contact urticaria and anaphylaxis from benzophenone-3(2-hydroxy 4-methoxy benzophenone).

  Contact dermatitis 20020101

• [Results of a French nationwide survey of cutaneous side effects of ketoprofen gel reported between September 1996 and August 2000].

  Therapie 20020101

• [Do sunscreen lotions have any endocrine effects?].

  Annales de dermatologie et de venereologie 20020101

• Thioredoxin reductase - its role in epidermal redox status.

  Journal of photochemistry and photobiology. B, Biology 20011115

• Report of 19 cases of photoallergic contact dermatitis to sunscreens seen at the Skin and Cancer Foundation.

  The Australasian journal of dermatology 20011101

• There is no influence of a temperature rise on in vivo adsorption of UV filters into the stratum corneum.

  Journal of dermatological science 20011001

• Solid lipid nanoparticles (SLN)--a novel carrier for UV blockers.

  Die Pharmazie 20011001

• Photoallergic contact dermatitis is uncommon.

  The British journal of dermatology 20011001

• [Photoaggravated contact allergy and contact photoallergy caused by ketoprofen: 19 cases].

  Annales de dermatologie et de venereologie 20011001

• LC separation of calcipotriol from its photodegradation products and protection possibilities using adjuvants.

  Journal of pharmaceutical and biomedical analysis 20010801

• Sequential injection spectrophotometric determination of oxybenzone in lipsticks.

  The Analyst 20010801

• Comments on 'In vitro and in vivo estrogenicity of UV screens'.

  Environmental health perspectives 20010801

• Skin permeation of two different benzophenone derivatives from various vehicles.

  International journal of cosmetic science 20010801

• Determination of the UV filters worldwide authorised in sunscreens by high-performance liquid chromatography. Use of cyclodextrins as mobile phase modifier.

  Journal of chromatography. A 20010706

• Can increasing the viscosity of formulations be used to reduce the human skin penetration of the sunscreen oxybenzone?

  The Journal of investigative dermatology 20010701

• Simultaneous photocontact sensitivity to ketoprofen and oxybenzone.

  Contact dermatitis 20010601

• Photosensitization of the sunscreen octyl p-dimethylaminobenzoate by UVA in human melanocytes but not in keratinocytes.

  Photochemistry and photobiology 20010601

• Determination of UV-filters in sunscreens by HPLC.

  Fresenius' journal of analytical chemistry 20010401

• Efficient flow injection and sequential injection methods for spectrophotometric determination of oxybenzone in sunscreens based on reaction with Ni(II).

  Fresenius' journal of analytical chemistry 20010401

• [Allergies to ketoprofen gels].

  Presse medicale (Paris, France : 1983) 20010331

• Anaphylaxis to oxybenzone, a frequent constituent of sunscreens.

  The Journal of allergy and clinical immunology 20010301

• Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

  Chemical research in toxicology 20010301

• In vitro and in vivo estrogenicity of UV screens.

  Environmental health perspectives 20010301

• Metabolic effects of dental resin components in vitro detected by NMR spectroscopy.

  Journal of dental research 20010301

• Five cases of photocontact dermatitis due to topical ketoprofen: photopatch testing and cross-reaction study.

  Photodermatology, photoimmunology & photomedicine 20010201

• Analgesic-induced asthma caused by 2.0% ketoprofen adhesive agents, but not by 0.3% agents.

  Internal medicine (Tokyo, Japan) 20010201