13280-60-9 | 5-Amino-2-nitrobenzoic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$22.00	$16.00
5g	98%(HPLC)	in stock	$48.00	$34.00
25g	97%	in stock	$137.00	$96.00
100g	95%	in stock	$329.00	$230.00

Description

• Catalog Number: AA48017
• Chemical Name: 5-Amino-2-nitrobenzoic acid
• CAS Number: 13280-60-9
• Molecular Formula: C7H6N2O4
• Molecular Weight: 182.1335
• MDL Number: MFCD00035748
• SMILES: Nc1ccc(c(c1)C(=O)O)[N+](=O)[O-]
• NSC Number: 74455

Computed Properties

• Complexity: 225
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.8

Upstream Synthesis Route

5-Amino-2-nitrobenzoic acid, also known as ANBA, serves a pivotal role in chemical synthesis as a versatile building block for the preparation of various compounds. This intermediate compound is widely used in organic chemistry for its significance in the production of pharmaceuticals, dyes, and other fine chemicals. In chemical synthesis, 5-Amino-2-nitrobenzoic acid undergoes a range of transformations to yield structurally diverse molecules. One common application involves the reduction of the nitro group to an amino group, enabling the formation of amino-substituted benzene derivatives. This reaction can be carried out through various methods, such as catalytic hydrogenation or chemical reduction using reagents like tin and acid.Furthermore, 5-Amino-2-nitrobenzoic acid can participate in coupling reactions with different reagents to generate amide, ester, or peptide linkages. These coupling reactions enable the incorporation of the ANBA moiety into more complex chemical structures, facilitating the synthesis of novel compounds with specific biological or material properties.Additionally, the presence of both amino and nitro groups in 5-Amino-2-nitrobenzoic acid allows for the selective functionalization of these sites through various chemical reactions. This versatility in functional group manipulation provides chemists with the flexibility to tailor the molecular properties of the final products for a wide range of applications in the pharmaceutical, agrochemical, and material science industries.

Literature

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