132911-42-3 | N-Methyl-1H-pyrrole-2-carboxamide

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$106.00	$75.00
5g	97%	in stock	$299.00	$209.00
25g	97%	in stock	$1,070.00	$749.00

Description

• Catalog Number: AA48228
• Chemical Name: N-Methyl-1H-pyrrole-2-carboxamide
• CAS Number: 132911-42-3
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.1405
• MDL Number: MFCD15143555
• SMILES: CNC(=O)c1ccc[nH]1

Computed Properties

• Complexity: 114
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.6

Literature

• Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents.

  Bioorganic & medicinal chemistry 20100601

• Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.

  Biochemistry 20090623

• DNA damage and cytotoxicity induced by minor groove binding methyl sulfonate esters.

  Biochemistry 20031209

• Antitumor AHMA linked to DNA minor groove binding agents: synthesis and biological evaluation.

  Journal of medicinal chemistry 20020926

• DNA binding properties of novel dansylated distamycin analogues in which the fluorophore is directly conjugated to the N-methyl-pyrrole.

  Journal of biomolecular structure & dynamics 20020401

• Unusual DNA binding exhibited by synthetic distamycin analogues lacking the N-terminal amide unit under high salt conditions.

  Journal of biomolecular structure & dynamics 20010601