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A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Toxicological sciences : an official journal of the Society of Toxicology 20131101
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Newer antipsychotics and upcoming molecules for schizophrenia.
European journal of clinical pharmacology 20130801
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Asenapine, iloperidone and lurasidone: critical appraisal of the most recently approved pharmacotherapies for schizophrenia in adults.
Expert review of clinical pharmacology 20130101
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New serotonin/dopamine antagonists for the treatment of schizophrenia: are we making real progress?
Clinical schizophrenia & related psychoses 20121001
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Pharmacological and clinical profile of recently approved second-generation antipsychotics: implications for treatment of schizophrenia in older patients.
Drugs & aging 20121001
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Iloperidone, asenapine and lurasidone: a primer on their current status.
Expert opinion on pharmacotherapy 20120901
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Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis.
CNS drugs 20120901
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Clinically important differences in the pharmacokinetics of the ten newer 'atypical' antipsychotics: Part 2. Metabolism and elimination.
Journal of psychiatric practice 20120901
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A systematic review of meta-analyses of the efficacy of oral atypical antipsychotics for the treatment of adult patients with schizophrenia.
Expert opinion on pharmacotherapy 20120801
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Iloperidone (FanaptĀ®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration.
Pharmacological research 20120701
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Weight gain and glucose dysregulation with second-generation antipsychotics and antidepressants: a review for primary care physicians.
Postgraduate medicine 20120701
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Summary of the comparative effectiveness review on off-label use of atypical antipsychotics.
Journal of managed care pharmacy : JMCP 20120601
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Clinically important differences in the pharmacokinetics of the ten newer 'atypical' antipsychotics: part 1.
Journal of psychiatric practice 20120501
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Iloperidone for the treatment of schizophrenia: an updated clinical review.
Clinical schizophrenia & related psychoses 20120401
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Analysis of gene variants previously associated with iloperidone response in patients with schizophrenia who are treated with risperidone.
The Journal of clinical psychiatry 20120301
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Effects of quetiapine and sertindole on subchronic ketamine-induced deficits in attentional set-shifting in rats.
Psychopharmacology 20120301
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Interactions between antiepileptics and second-generation antipsychotics.
Expert opinion on drug metabolism & toxicology 20120301
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The pharmacogenetics of symptom response to antipsychotic drugs.
Psychiatry investigation 20120301
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Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration database.
PLoS medicine 20120301
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The psychopharmacology of agitation: consensus statement of the american association for emergency psychiatry project Beta psychopharmacology workgroup.
The western journal of emergency medicine 20120201
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Efficacy of iloperidone in the short-term treatment of schizophrenia: a post hoc analysis of pooled patient data from four phase III, placebo- and active-controlled trials.
Human psychopharmacology 20120101
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The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.
Parkinson's disease 20120101
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Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology.
Frontiers in pharmacology 20120101
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Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.
Substance abuse treatment, prevention, and policy 20120101
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Critical appraisal of lurasidone in the management of schizophrenia.
Neuropsychiatric disease and treatment 20120101
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Atypical antipsychotic drugs, schizophrenia, and metabolic syndrome in non-Euro-American societies.
Clinical neuropharmacology 20120101
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Angioedema occurring in patient prescribed iloperidone and haloperidol: a cross-sensitivity reaction to antipsychotics from different chemical classes.
The Journal of neuropsychiatry and clinical neurosciences 20120101
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Biological perspectives: update on newer antipsychotic drugs: are they evidence based?
Perspectives in psychiatric care 20111001
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Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis.
JAMA 20110928
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Efficacy of iloperidone in schizophrenia: a PANSS five-factor analysis.
Schizophrenia research 20110901
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Update on newer antipsychotic drugs.
Journal of psychosocial nursing and mental health services 20110401
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Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics.
Postgraduate medicine 20110301
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Iloperidone for the management of adults with schizophrenia.
Clinical therapeutics 20110301
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Iloperidone: Does it have a meaningful place in therapy?
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110215
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Iloperidone: A new drug for the treatment of schizophrenia.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110215
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The role of serotonin receptors in the action of atypical antipsychotic drugs.
Current opinion in pharmacology 20110201
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Atypical antipsychotics: the two new arrivals.
Issues in mental health nursing 20110101
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Weight gain, obesity, and psychotropic prescribing.
Journal of obesity 20110101
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The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder.
Neuropsychiatric disease and treatment 20110101
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Role of sublingual asenapine in treatment of schizophrenia.
Neuropsychiatric disease and treatment 20110101
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Genomewide association scan of suicidal thoughts and behaviour in major depression.
PloS one 20110101
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Clinical potential of lurasidone in the management of schizophrenia.
Therapeutics and clinical risk management 20110101
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Is the PANSS used correctly? a systematic review.
BMC psychiatry 20110101
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Clinical utility of the risperidone formulations in the management of schizophrenia.
Neuropsychiatric disease and treatment 20110101
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Iloperidone: a clinical overview.
The Journal of clinical psychiatry 20110101
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Iloperidone: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability, regulatory affairs, and an opinion.
Expert opinion on drug metabolism & toxicology 20101201
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A review of new atypical antipsychotic launches in the United States.
Psychiatry (Edgmont (Pa. : Township)) 20101201
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The effect of metformin on anthropometrics and insulin resistance in patients receiving atypical antipsychotic agents: a meta-analysis.
The Journal of clinical psychiatry 20101001
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New antipsychotic drugs: how do their receptor-binding profiles compare?
The Journal of clinical psychiatry 20100901
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Iloperidone for schizophrenia.
Expert opinion on pharmacotherapy 20100801
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Iloperidone for the treatment of schizophrenia.
Drugs of today (Barcelona, Spain : 1998) 20100801
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Atypical antipsychotic metabolism and excretion.
Current drug metabolism 20100701
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Iloperidone redux: a dissection of the Drug Approval Package for this newly commercialised second-generation antipsychotic.
International journal of clinical practice 20100501
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Iloperidone for the treatment of schizophrenia.
The Annals of pharmacotherapy 20100501
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Absence of weight gain association with the HTR2C -759C/T polymorphism in patients with schizophrenia treated with iloperidone.
Psychiatry research 20100227
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Iloperidone (Fanapt)--another second-generation antipsychotic.
The Medical letter on drugs and therapeutics 20100222
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New drugs: asenapine, iloperidone, and bepotastine besilate.
Journal of the American Pharmacists Association : JAPhA 20100101
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New atypical antipsychotics for schizophrenia: iloperidone.
Drug design, development and therapy 20100101
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20100101
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Iloperidone: a new option for the treatment of schizophrenia.
Expert review of neurotherapeutics 20091201
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Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.
Molecular psychiatry 20091101
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Iloperidone: in schizophrenia.
CNS drugs 20091001
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Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study.
Molecular psychiatry 20090801
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Iloperidone for schizophrenia: a review of the efficacy and safety profile for this newly commercialised second-generation antipsychotic.
International journal of clinical practice 20090801
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Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.
The Journal of clinical psychiatry 20090601
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Akathisia and second-generation antipsychotic drugs.
Current opinion in psychiatry 20090501
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Further characterization of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in C57BL/6 mice: role of 5-HT(2A) serotonergic and alpha (1) adrenergic antagonism.
Psychopharmacology 20090401
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Pharmacogenomics: the promise of personalized medicine for CNS disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101
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Genome-wide association studies in pharmacogenomics: untapped potential for translation.
Genome medicine 20090101
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20081001
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American psychiatric association.
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Journal of clinical psychopharmacology 20080401
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Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials.
Journal of clinical psychopharmacology 20080401
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Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia.
Journal of clinical psychopharmacology 20080401
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Long-term efficacy and safety of iloperidone: results from 3 clinical trials for the treatment of schizophrenia.
Journal of clinical psychopharmacology 20080401
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Efficacy of iloperidone in the treatment of schizophrenia: initial phase 3 studies.
Journal of clinical psychopharmacology 20080401
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Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial.
Pharmacogenomics 20080301
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Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market?
Expert opinion on investigational drugs 20080101
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Gateways to clinical trials. July-August 2008.
Methods and findings in experimental and clinical pharmacology 20080101
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Upcoming agents for the treatment of schizophrenia: mechanism of action, efficacy and tolerability.
Drugs 20080101
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Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats.
Neuropharmacology 20060901
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Atypical antipsychotics: pharmacokinetics, therapeutic drug monitoring and pharmacological interactions.
Current medicinal chemistry 20040201
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Differential effects of iloperidone, clozapine, and haloperidol on working memory of rats in the delayed non-matching-to-position paradigm.
Psychopharmacology 20030901
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Functional characterization of the novel antipsychotic iloperidone at human D2, D3, alpha 2C, 5-HT6, and 5-HT1A receptors.
Life sciences 20030718
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alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
European journal of pharmacology 20030221
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Effects of clozapine, haloperidol and iloperidone on neurotransmission and synaptic plasticity in prefrontal cortex and their accumulation in brain tissue: an in vitro study.
Neuroscience 20030101
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Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism.
Brain research 20021129
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20021101
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New antipsychotic agents for schizophrenia: pharmacokinetics and metabolism update.
Current opinion in investigational drugs (London, England : 2000) 20020701
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Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone.
Progress in neuro-psychopharmacology & biological psychiatry 20020401
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Advances in atypical antipsychotics for the treatment of schizophrenia: new formulations and new agents.
CNS drugs 20020101
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Iloperidone (Novartis).
IDrugs : the investigational drugs journal 20020101
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Extended radioligand binding profile of iloperidone: a broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20011201
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Treatments for chronic psychosis.
Dialogues in clinical neuroscience 20011201
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Iloperidone (Hoechst Marion Roussel Inc).
IDrugs : the investigational drugs journal 19990601
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Iloperidone binding to human and rat dopamine and 5-HT receptors.
European journal of pharmacology 19961219
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The pharmacological profile of iloperidone, a novel atypical antipsychotic agent.
The Journal of pharmacology and experimental therapeutics 19950901
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The ratios of serotonin2 and dopamine2 affinities differentiate atypical and typical antipsychotic drugs.
Psychopharmacology bulletin 19890101