1338247-35-0 | BMS-5

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$62.00	$44.00
5mg	98%	in stock	$89.00	$63.00
25mg	98%	in stock	$154.00	$108.00
50mg	98%	in stock	$260.00	$182.00
100mg	98%	in stock	$312.00	$219.00

Description

• Catalog Number: AE36051
• Chemical Name: BMS-5
• CAS Number: 1338247-35-0
• Molecular Formula: C17H14Cl2F2N4OS
• Molecular Weight: 431.28706639999984
• MDL Number: MFCD17019327
• SMILES: O=C(C(C)C)Nc1ncc(s1)c1cc(nn1c1c(Cl)cccc1Cl)C(F)F

Computed Properties

• Complexity: 523
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 5.1

Literature

• Inhibition of human prostate smooth muscle contraction by the LIM kinase inhibitors, SR7826 and LIMKi3.

  British journal of pharmacology 20180601

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• The actin-severing protein cofilin is downstream of neuregulin signaling and is essential for Schwann cell myelination.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120411

• LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells.

  The Journal of cell biology 20101004

• Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors.

  Molecular cancer therapeutics 20081101