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AB45479

134-58-7 | 8-Azaguanine

Packsize Purity Availability Price Discounted Price    Quantity
1g 95% in stock $34.00 $24.00 -   +
5g 95% in stock $94.00 $66.00 -   +
10g 95% in stock $169.00 $118.00 -   +
25g 95% in stock $356.00 $249.00 -   +
100g 95% in stock $1,195.00 $836.00 -   +

*All products are for research use only and not intended for human or animal use.

*All prices are in USD.

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Description
Catalog Number: AB45479
Chemical Name: 8-Azaguanine
CAS Number: 134-58-7
Molecular Formula: C4H4N6O
Molecular Weight: 152.1142
MDL Number: MFCD00056937
SMILES: Nc1nc(=O)c2c([nH]1)nn[nH]2

 

Computed Properties
Complexity: 225  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 11  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
XLogP3: -1.5  

 

 

Upstream Synthesis Route 
  • 8-Azaguanine, also known as 8-AG, is a valuable compound widely used in chemical synthesis due to its unique properties and functionality. In organic chemistry, 8-Azaguanine serves as a key building block for the synthesis of various nucleoside analogs and pharmaceuticals. Its ability to mimic guanine allows for the creation of modified nucleic acids with altered biological activities.One prominent application of 8-Azaguanine is in the development of antiviral and anticancer agents. By incorporating 8-Azaguanine into nucleoside analogs, scientists can design compounds that selectively target viral or cancerous cells while minimizing harm to healthy cells. This specificity is crucial for the development of effective and safe treatments for these diseases.Furthermore, 8-Azaguanine is utilized in research settings to study nucleic acid structure and function. Its presence in synthetic oligonucleotides can provide insights into the interactions between nucleic acids and proteins, as well as the mechanisms of DNA replication and repair. By incorporating 8-Azaguanine into nucleic acid probes, researchers can enhance the sensitivity and specificity of their experiments.Overall, the versatility and utility of 8-Azaguanine make it a valuable tool in chemical synthesis, particularly in the design and development of novel nucleoside analogs and pharmaceutical compounds. Its applications in antiviral and anticancer drug discovery, as well as in nucleic acid research, highlight its importance in advancing our understanding of biological processes and developing new therapeutics.
Literature
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