134-90-7 | L-(+)-Threo-chloramphenicol

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$49.00	$34.00
5g	97%	in stock	$105.00	$74.00
25g	97%	in stock	$297.00	$208.00
100g	97%	in stock	$758.00	$531.00

Description

• Catalog Number: AE39854
• Chemical Name: L-(+)-Threo-chloramphenicol
• CAS Number: 134-90-7
• Molecular Formula: C11H12Cl2N2O5
• Molecular Weight: 323.12938
• MDL Number: MFCD01733852
• SMILES: OC[C@@H]([C@H](c1ccc(cc1)N(=O)=O)O)NC(=O)C(Cl)Cl

Computed Properties

• Complexity: 342
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: 1.1

Literature

• Synthesis, spectroscopic, thermal and antimicrobial studies of toluene-3,4-dithiolatoarsenic(III) derivatives with some oxygen and sulphur donor ligands.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

• [Polymicrobial brain abscess in hereditary haemorrhagic telangiectasia (Osler's disease)].

  Deutsche medizinische Wochenschrift (1946) 20120801

• Characterisation and application of molecularly imprinted polymers for group-selective recognition of antibiotics in food samples.

  The Analyst 20120721

• Antimicrobial susceptibility testing of Shiga toxin-producing Escherichia coli from various samples by using a spiral gradient endpoint technique.

  Foodborne pathogens and disease 20120101

• Stress degradation studies and development of stability-indicating TLC-densitometry method for determination of prednisolone acetate and chloramphenicol in their individual and combined pharmaceutical formulations.

  Chemistry Central journal 20120101

• Recurrent sepsis due to bacillus licheniformis.

  Journal of global infectious diseases 20120101

• In vivo and in vitro function of human UDP-galactose 4'-epimerase variants.

  Biochimie 20111001

• Invasive Bacterial Pathogens and their Antibiotic Susceptibility Patterns in Jimma University Specialized Hospital, Jimma, Southwest Ethiopia.

  Ethiopian journal of health sciences 20110301

• Optimization and validation of the micellar electrokinetic capillary chromatographic method for simultaneous determination of sulfonamide and amphenicol-type drugs in poultry tissue.

  Journal of pharmaceutical and biomedical analysis 20110105

• Clinical characteristics and therapeutic outcomes of nosocomial super-infection in adult bacterial meningitis.

  BMC infectious diseases 20110101

• Functional identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B12 synthesis.

  Microbial cell factories 20110101

• Pasteurella multocida involved in respiratory disease of wild chimpanzees.

  PloS one 20110101

• A conformational switch in the active site of BT_2972, a methyltransferase from an antibiotic resistant pathogen B. thetaiotaomicron.

  PloS one 20110101

• Development of phage-based single chain Fv antibody reagents for detection of Yersinia pestis.

  PloS one 20110101

• Differential heat stability of amphenicols characterized by structural degradation, mass spectrometry and antimicrobial activity.

  Journal of pharmaceutical and biomedical analysis 20101201

• Synthesis and antimicrobial activity of some new thiazole, thiophene and pyrazole derivatives containing benzothiazole moiety.

  European journal of medicinal chemistry 20100901

• Relationships between chemical oxygen demand (COD) components and toxicity in a sequential anaerobic baffled reactor/aerobic completely stirred reactor system treating Kemicetine.

  Journal of hazardous materials 20100415

• 3-Methyl-1-butanol production in Escherichia coli: random mutagenesis and two-phase fermentation.

  Applied microbiology and biotechnology 20100401

• Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene.

  BMC genomics 20100101

• Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b.

  PloS one 20100101

• Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis.

  Molecular systems biology 20100101

• Antimicrobial resistance of nosocomial strain of Acinetobacter baumannii in Children's Medical Center of Tehran: a 6-year prospective study.

  Acta medica Iranica 20100101

• Prevention, treatment and rehabilitation.

  Community eye health 20091201

• Cloning and functional characterization of carotenoid cleavage dioxygenase 4 genes.

  Journal of experimental botany 20090701

• Rab11A-controlled assembly of the inner membrane complex is required for completion of apicomplexan cytokinesis.

  PLoS pathogens 20090101

• Latherin: a surfactant protein of horse sweat and saliva.

  PloS one 20090101

• Mage-b vaccine delivered by recombinant Listeria monocytogenes is highly effective against breast cancer metastases.

  British journal of cancer 20080902

• Characteristics of the Turkish isolates of Francisella tularensis.

  Japanese journal of infectious diseases 20080501

• Isolation of Scopulariopsis spp. fungi from Psoroptes cuniculi body surface and evaluation of their entomopathogenic role.

  Parasitology research 20080401

• A study on tinea gladiatorum in young wrestlers and dermatophyte contamination of wrestling mats from Sari, Iran.

  British journal of sports medicine 20070501

• Expression, purification and crystallization of 2-oxo-hept-4-ene-1,7-dioate hydratase (HpcG) from Escherichia coli C.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20061001

• Conserved and variable functions of the sigmaE stress response in related genomes.

  PLoS biology 20060101

• A Role for the SmpB-SsrA system in Yersinia pseudotuberculosis pathogenesis.

  PLoS pathogens 20060101

• Amphenicol and macrolide derived antibiotics inhibit paraoxonase enzyme activity in human serum and human hepatoma cells (HepG2) in vitro.

  Biochemistry. Biokhimiia 20060101

• Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages.

  Arthritis research & therapy 20060101

• Separation of basic compounds by capillary electrochromatography on an X-Terra RP18 stationary phase.

  Journal of chromatography. A 20040917

• [Study of antibiotic influence on adherence capacity of gram positive and gram negative bacteria to the cellular substrate].

  Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990) 20020101

• [Retrospective clinical analysis of the emergent comprehensive repair of electrical injury].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20010201

• [Drug resistance of Staphylococcus aureus strains, isolated from children with intestinal dysbacteriosis].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20010101