1351635-67-0 | Ono-4059

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$29.00	$20.00
5mg	98%	in stock	$71.00	$50.00
10mg	98%	in stock	$107.00	$75.00

Description

• Catalog Number: AE35956
• Chemical Name: Ono-4059
• CAS Number: 1351635-67-0
• Molecular Formula: C25H24N6O3
• Molecular Weight: 456.4965
• MDL Number: MFCD29049511
• SMILES: C=CC(=O)N1CCCC(C1)n1c(=O)n(c2c1ncnc2N)c1ccc(cc1)Oc1ccccc1

Computed Properties

• Complexity: 751
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 2.9

Literature

• A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies.

  Blood 20160128