1351636-18-4 | Ono-4059

Packsize	Purity	Availability	Price	Discounted Price
10mg	98%	in stock	$141.00	$99.00

Description

• Catalog Number: AE35615
• Chemical Name: Ono-4059
• CAS Number: 1351636-18-4
• Molecular Formula: C25H22N6O3
• Molecular Weight: 454.48058
• MDL Number: MFCD28386296
• SMILES: CC#CC(=O)N1CC[C@H](C1)n1c(=O)n(c2c1ncnc2N)c1ccc(cc1)Oc1ccccc1

Computed Properties

• Complexity: 825
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 3

Literature

• A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies.

  Blood 20160128