1352608-82-2 | EW 7197

Packsize	Purity	Availability	Price	Discounted Price
2mg	98%	in stock	$23.00	$17.00
5mg	98%	in stock	$29.00	$20.00
25mg	98%	in stock	$108.00	$76.00
50mg	98%	in stock	$111.00	$78.00
100mg	98%	in stock	$186.00	$130.00
250mg	98%	in stock	$314.00	$220.00
1g	98%	in stock	$849.00	$595.00

Description

• Catalog Number: AB53168
• Chemical Name: EW 7197
• CAS Number: 1352608-82-2
• Molecular Formula: C22H18FN7
• Molecular Weight: 399.4236232
• MDL Number: MFCD28348363
• SMILES: Cc1cccc(n1)c1[nH]c(nc1c1ccc2n(c1)ncn2)CNc1ccccc1F

Computed Properties

• Complexity: 566
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 3.2

Literature

• Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): a highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent.

  Journal of medicinal chemistry 20140522