13553-79-2 | Rifamycin s

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$44.00	$31.00
1g	98%	in stock	$74.00	$52.00
5g	98%	in stock	$224.00	$157.00

Description

• Catalog Number: AB46988
• Chemical Name: Rifamycin s
• CAS Number: 13553-79-2
• Molecular Formula: C37H45NO12
• Molecular Weight: 695.7527
• MDL Number: MFCD06198807
• SMILES: CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c2C(=O)C=C(C(=O)c2c(c3C)O)NC(=O)C(=CC=C[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]1C)OC(=O)C)C)O)C)O)C)C

Computed Properties

• Complexity: 1480
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 9
• Defined Bond Stereocenter Count: 3
• Heavy Atom Count: 50
• Hydrogen Bond Acceptor Count: 12
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 3
• XLogP3: 4.1

Literature

• Detoxification of toxins by bacillithiol in Staphylococcus aureus.

  Microbiology (Reading, England) 20120401

• Synthesis and structure-activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin.

  Bioorganic & medicinal chemistry letters 20111015

• Direct generation of acyclic polypropionate stereopolyads via double diastereo- and enantioselective iridium-catalyzed crotylation of 1,3-diols: beyond stepwise carbonyl addition in polyketide construction.

  Journal of the American Chemical Society 20110817

• Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica.

  Antonie van Leeuwenhoek 20090201

• Preparation and in vitro anti-staphylococcal activity of novel 11-deoxy-11-hydroxyiminorifamycins.

  Bioorganic & medicinal chemistry letters 20071015

• Hygrocins a and B, naphthoquinone macrolides from Streptomyces hygroscopicus.

  Journal of natural products 20051201

• NMR spectroscopic analysis of new spiro-piperidylrifamycins.

  Magnetic resonance in chemistry : MRC 20050401

• Expeditious asymmetric synthesis of a stereoheptad corresponding to the C(19)-C(27)-ansa chain of rifamycins: formal total synthesis of Rifamycin S.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050107

• Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.

  Biochemistry 20031021

• Solid state cultivation of Curvularia lunata for transformation of rifamycin B to S.

  Indian journal of experimental biology 20020801

• Efficient strategy for the synthesis of stereopentad subunits of scytophycin, rifamycin S, and discodermolide.

  Organic letters 20011213

• Oxabicyclo[3.2.1]octenes in organic synthesis--direct ring opening of oxabicyclo[3.2.1] systems employing silyl ketene acetals in concentrated solutions of lithium perchlorate-diethyl ether: application to the synthesis of the C(19)-C(27) fragment of rifamycin S.

  Organic letters 20010208

• Structure-activity relationships in open ansa-chain rifamycin S derivatives as inhibitors of HIV-1 reverse transcriptase.

  Farmaco (Societa chimica italiana : 1989) 19950901