1357470-29-1 | On-123300

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$35.00	$24.00
2mg	98%	in stock	$48.00	$33.00
5mg	98%	in stock	$65.00	$45.00
10mg	98%	in stock	$96.00	$67.00
50mg	98%	in stock	$255.00	$178.00
100mg	98%	in stock	$409.00	$286.00
250mg	98%	in stock	$709.00	$496.00
1g	98%	in stock	$1,850.00	$1,295.00

Description

• Catalog Number: AE36098
• Chemical Name: On-123300
• CAS Number: 1357470-29-1
• Molecular Formula: C24H27N7O
• Molecular Weight: 429.5175
• MDL Number: MFCD28411414
• SMILES: N#Cc1cc2cnc(nc2n(c1=O)C1CCCC1)Nc1ccc(cc1)N1CCN(CC1)C

Computed Properties

• Complexity: 754
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 3.1

Literature

• Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma.

  Cancer research 20160301

• Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.

  Leukemia 20160101

• Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models.

  Molecular cancer therapeutics 20140501

• [10th session of the Oesterreichische Gesellschaft für Unfallchirurgie, Oct. 11-12, 1974 Salzburg. Opening address].

  Hefte zur Unfallheilkunde 19750101