1358-76-5 | Koumine

Packsize	Purity	Availability	Price	Discounted Price
1mg	≥98%	in stock	$115.00	$81.00
5mg	≥98%	in stock	$429.00	$300.00
10mg	≥98%	in stock	$744.00	$521.00
20mg		in stock	$814.00	$570.00

Description

• Catalog Number: AE41296
• Chemical Name: Koumine
• CAS Number: 1358-76-5
• Molecular Formula: C20H22N2O
• Molecular Weight: 306.4015
• MDL Number: MFCD11111448
• SMILES: C=C[C@]12CN(C)[C@@H]3[C@@H]4[C@H]1C[C@H](C1=Nc5c([C@]21C3)cccc5)OC4

Computed Properties

• Complexity: 615
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 6
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 2.5

Literature

• Effects of koumine, an alkaloid of Gelsemium elegans Benth., on inflammatory and neuropathic pain models and possible mechanism with allopregnanolone.

  Pharmacology, biochemistry, and behavior 20120501

• [Study on anti-proliferation activity and the mechanisms of alkaloid monomers from Gelsemium elegans on HepG2 cell in vitro].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120301

• Preparative separation of alkaloids from Gelsemium elegans Benth. using pH-zone-refining counter-current chromatography.

  Journal of chromatography. A 20110610

• [Antineoplastic effect of koumine in mice bearing H22 solid tumor].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901

• [Koumine-induced apoptosis of human colonic adenocarcinoma cells: the cell biological mechanism].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070701

• Tandem photocycloaddition-retro-mannich fragmentation of enaminones. A route to spiropyrrolines and the tetracyclic core of koumine.

  Organic letters 20060316

• [Therapeutic effects of koumine on psoriasis: an experimental study in mice].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050501

• [Effect of koumine on proliferation of murine CD4+ T cells purified by magnetic-activated cell sorting in vitro].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050501