136834-21-4 | 5'-O-Dmt-n6-benzoyl-2'-fluoro-2'-deoxyadenosine

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$13.00	$9.00
250mg	98%	in stock	$29.00	$20.00
1g	98%	in stock	$93.00	$65.00

Description

• Catalog Number: AA49601
• Chemical Name: 5'-O-Dmt-n6-benzoyl-2'-fluoro-2'-deoxyadenosine
• CAS Number: 136834-21-4
• Molecular Formula: C38H34FN5O6
• Molecular Weight: 675.7049
• MDL Number: MFCD15145191
• SMILES: COc1ccc(cc1)C(c1ccc(cc1)OC)(c1ccccc1)OC[C@H]1O[C@H]([C@@H]([C@@H]1O)F)n1cnc2c1ncnc2NC(=O)c1ccccc1

Upstream Synthesis Route

DMT-2'-F-Bz-dA is a crucial compound used in chemical synthesis, particularly in the field of nucleic acid research. This derivative of 2'-deoxyadenosine, with a dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl and a benzoyl (Bz) protecting group on the 3'-hydroxyl, plays a significant role in the synthesis of oligonucleotides.In chemical synthesis, DMT-2'-F-Bz-dA acts as a key building block for the creation of modified oligonucleotides. The specific modifications on the deoxyadenosine base enable researchers to incorporate this derivative into custom-designed nucleic acid sequences with precise control over the placement of the modified nucleotide. This is essential for various applications, including the study of nucleic acid structure and function, the development of therapeutic nucleic acid-based drugs, and the creation of novel biomaterials.Furthermore, the DMT and Bz protecting groups on DMT-2'-F-Bz-dA are crucial for ensuring selective deprotection and coupling reactions during oligonucleotide synthesis. By strategically removing these protecting groups at specific steps in the synthesis process, chemists can precisely control the addition of DMT-2'-F-Bz-dA into the growing oligonucleotide chain, leading to the successful assembly of complex nucleic acid sequences with high purity and yield.Overall, DMT-2'-F-Bz-dA is a versatile compound with important applications in chemical synthesis, particularly in the controlled construction of modified oligonucleotides for various research, therapeutic, and biotechnological purposes.