-
Tolfenamic acid downregulates BACE1 and protects against lead-induced upregulation of Alzheimer's disease related biomarkers.
Neuropharmacology 20140401
-
Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.
Chemico-biological interactions 20130225
-
Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer.
The Prostate 20121101
-
Simultaneous determination of mefenamic and tolfenamic acids in real samples by terbium-sensitized luminescence.
Journal of fluorescence 20121101
-
Structure-activity relationship of fenamates as Slo2.1 channel activators.
Molecular pharmacology 20121101
-
Raman and IR spectroscopic studies of fenamates--conformational differences in polymorphs of flufenamic acid, mefenamic acid and tolfenamic acid.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001
-
Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver.
Integrative biology : quantitative biosciences from nano to macro 20120921
-
Development and validation of two multiresidue liquid chromatography tandem mass spectrometry methods based on a versatile extraction procedure for isolating non-steroidal anti-inflammatory drugs from bovine milk and muscle tissue.
Analytical and bioanalytical chemistry 20120901
-
Determination of non-steroidal anti-inflammatory drugs and their metabolites in milk by liquid chromatography-tandem mass spectrometry.
Analytical and bioanalytical chemistry 20120701
-
Structural features of mono- and tri-nuclear Zn(II) complexes with a non-steroidal anti-inflammatory drug as ligand.
Dalton transactions (Cambridge, England : 2003) 20120621
-
Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.
Investigational new drugs 20120601
-
Italian guidelines for primary headaches: 2012 revised version.
The journal of headache and pain 20120501
-
Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis.
Journal of natural products 20120427
-
Evaluating the effects of 14-day oral vedaprofen and tolfenamic acid treatment on renal function, hematological and biochemical profiles in healthy cats.
Journal of veterinary pharmacology and therapeutics 20120201
-
Polymorph formation and nucleation mechanism of tolfenamic acid in solution: an investigation of pre-nucleation solute association.
Pharmaceutical research 20120201
-
Cobalt(II) complexes with non-steroidal anti-inflammatory drug tolfenamic acid: Structure and biological evaluation.
European journal of medicinal chemistry 20120201
-
Activating transcription factor 3 and the nervous system.
Frontiers in molecular neuroscience 20120101
-
Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: involvement of NAG-1 expression.
PloS one 20120101
-
Effect of tolfenamic acid on canine cancer cell proliferation, specificity protein (sp) transcription factors, and sp-regulated proteins in canine osteosarcoma, mammary carcinoma, and melanoma cells.
Journal of veterinary internal medicine 20120101
-
Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer.
PloS one 20120101
-
Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy.
Current medicinal chemistry 20120101
-
Anti-inflammatory drugs and prediction of new structures by comparative analysis.
Anti-inflammatory & anti-allergy agents in medicinal chemistry 20120101
-
9,10-phenanthrenequinone induces monocytic differentiation of U937 cells through regulating expression of aldo-keto reductase 1C3.
Biological & pharmaceutical bulletin 20120101
-
The ability of tolfenamic acid to penetrate the brain: a model for testing the brain disposition of candidate Alzheimer's drugs using multiple platforms.
Current Alzheimer research 20111201
-
Interplay between molecular conformation and intermolecular interactions in conformational polymorphism: a molecular perspective from electronic calculations of tolfenamic acid.
International journal of pharmaceutics 20111014
-
Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase.
The Journal of pharmacology and experimental therapeutics 20111001
-
Development and validation of a confirmatory method for the determination of 12 non steroidal anti-inflammatory drugs in milk using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A 20110916
-
Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in calves.
Journal of veterinary pharmacology and therapeutics 20110801
-
Optimization of the derivatization reaction and the solid-phase microextraction conditions using a D-optimal design and three-way calibration in the determination of non-steroidal anti-inflammatory drugs in bovine milk by gas chromatography-mass spectrometry.
Journal of chromatography. A 20110715
-
Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma.
Oral diseases 20110701
-
Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors.
Gynecologic oncology 20110701
-
Tolfenamic acid interrupts the de novo synthesis of the β-amyloid precursor protein and lowers amyloid beta via a transcriptional pathway.
Current Alzheimer research 20110601
-
Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.
Chemico-biological interactions 20110530
-
Apoptotic effect of tolfenamic acid in androgen receptor-independent prostate cancer cell and xenograft tumor through specificity protein 1.
Cancer science 20110401
-
Combined treatment of pancreatic cancer with mithramycin a and tolfenamic Acid promotes sp1 degradation and synergistic antitumor activity--letter.
Cancer research 20110401
-
Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20110301
-
Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice.
Investigational new drugs 20110201
-
Therapeutic applications of NSAIDS in cancer: special emphasis on tolfenamic acid.
Frontiers in bioscience (Scholar edition) 20110101
-
Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: case report.
Acta veterinaria Scandinavica 20110101
-
Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?
BMC neurology 20110101
-
Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.
BMC cancer 20110101
-
Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.
PloS one 20110101
-
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
Healthcare informatics research 20101201
-
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
-
Postoperative analgesic efficacy of meloxicam compared to tolfenamic acid in cats undergoing orthopaedic surgery.
The Journal of small animal practice 20101001
-
Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways.
Oncogene 20100916
-
Occurrence and risk assessment of acidic pharmaceuticals in the Yellow River, Hai River and Liao River of north China.
The Science of the total environment 20100715
-
Analytical strategy for the determination of non-steroidal anti-inflammatory drugs in plasma and improved analytical strategy for the determination of authorized and non-authorized non-steroidal anti-inflammatory drugs in milk by LC-MS/MS.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100701
-
Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway.
Journal of clinical biochemistry and nutrition 20100701
-
Novel milk-based oral formulations: proof of concept.
International journal of pharmaceutics 20100510
-
Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in goats.
Veterinary journal (London, England : 1997) 20100501
-
Confirmatory analysis of non-steroidal anti-inflammatory drugs in bovine milk by high-performance liquid chromatography with fluorescence detection.
Journal of chromatography. A 20100423
-
Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.
Dalton transactions (Cambridge, England : 2003) 20100321
-
Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity.
Cancer research 20100201
-
Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial.
BMJ (Clinical research ed.) 20100101
-
Thermodynamic and structural study of tolfenamic acid polymorphs.
Journal of pharmaceutical and biomedical analysis 20091205
-
Development of a rapid, multi-class method for the confirmatory analysis of anti-inflammatory drugs in bovine milk using liquid chromatography tandem mass spectrometry.
Journal of chromatography. A 20091113
-
Eicosanoids influence insect susceptibility to nucleopolyhedroviruses.
Journal of invertebrate pathology 20091101
-
Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met.
Carcinogenesis 20090701
-
Anti-inflammatory, antiproliferative, and radical-scavenging activities of tolfenamic acid and its metal complexes.
Chemistry & biodiversity 20090601
-
The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression.
Molecular cancer therapeutics 20090501
-
The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury.
Toxicology letters 20090425
-
Polymer-induced heteronucleation of tolfenamic acid: structural investigation of a pentamorph.
Journal of the American Chemical Society 20090408
-
Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression.
Molecular cancer therapeutics 20090301
-
Thermodynamics of lipophilic drug binding to intestinal fatty acid binding protein and permeation across membranes.
Molecular pharmaceutics 20090101
-
Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification.
Breast cancer research : BCR 20090101
-
Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.
Retrovirology 20090101
-
ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells.
Molecular cancer therapeutics 20081201
-
Current migraine management - patient acceptability and future approaches.
Neuropsychiatric disease and treatment 20081201
-
Efficacy of tolfenamic acid and meloxicam in the control of postoperative pain following ovariohysterectomy in the cat.
Veterinary anaesthesia and analgesia 20081101
-
Assessment of the duration of the pain response associated with lameness in dairy cows, and the influence of treatment.
New Zealand veterinary journal 20081001
-
Optimizing prophylactic treatment of migraine: Subtypes and patient matching.
Therapeutics and clinical risk management 20081001
-
Poloxamer 407 as a solubilising agent for tolfenamic acid and as a base for a gel formulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080902
-
Effects of meloxicam or tolfenamic acid administration on the pain and stress responses of Merino lambs to mulesing.
Australian veterinary journal 20080801
-
In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions.
Basic & clinical pharmacology & toxicology 20080801
-
Effects of fenamate on inhibitory postsynaptic currents in Purkinje's cells.
Bulletin of experimental biology and medicine 20080501
-
catena-Poly[[bis-[2-(2,3-dimethyl-anilino)benzoato-κO]cadmium(II)]-di-μ-3-pyridylmethanol-κN:O;κO:N].
Acta crystallographica. Section E, Structure reports online 20080301
-
The effect of suspended particles coated by humic acid on the toxicity of pharmaceuticals, estrogens, and phenolic compounds.
Environment international 20080201
-
Confirmatory identification of sixteen non-steroidal anti-inflammatory drug residues in raw milk by liquid chromatography coupled with ion trap mass spectrometry.
Rapid communications in mass spectrometry : RCM 20080101
-
Field evaluation of the efficacy of tolfenamic acid administered in one single preoperative injection for the prevention of postoperative pain in the dog.
Journal of veterinary pharmacology and therapeutics 20071201
-
Inhibition of human thiopurine S-methyltransferase by various nonsteroidal anti-inflammatory drugs in vitro: a mechanism for possible drug interactions.
Drug metabolism and disposition: the biological fate of chemicals 20070901
-
Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation.
European journal of clinical pharmacology 20070901
-
Nonsteroidal anti-inflammatory drugs in cats: a review.
Veterinary anaesthesia and analgesia 20070701
-
Eicosanoid biosynthesis inhibitors increase the susceptibility of Lymantria dispar to nucleopolyhedrovirus LdMNPV.
Journal of invertebrate pathology 20070601
-
Acute migraine: Current treatment and emerging therapies.
Therapeutics and clinical risk management 20070601
-
Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.
Cancer research 20070401
-
Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
The Journal of biological chemistry 20070316
-
Rapid method for the determination of non-steroidal anti-inflammatory drugs in animal tissue by liquid chromatography-mass spectrometry with ion-trap detector.
Analytica chimica acta 20070314
-
Characterization and physical stability of tolfenamic acid-PVP K30 solid dispersions.
Pharmaceutical development and technology 20070101
-
The use of combination therapies in the acute management of migraine.
Neuropsychiatric disease and treatment 20060901
-
Nutraceutical inhibitors of urokinase: potential applications in prostate cancer prevention and treatment.
Oncology reports 20060801
-
Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation.
Journal of the National Cancer Institute 20060621
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Involvement of opioidergic and alpha2-adrenergic mechanisms in the central analgesic effects of non-steroidal anti-inflammatory drugs in sheep.
Research in veterinary science 20060401
-
Pharmacokinetic and pharmacodynamic interactions of tolfenamic acid and marbofloxacin in goats.
Research in veterinary science 20060201
-
Determination of fourteen non-steroidal anti-inflammatory drugs in animal serum and plasma by liquid chromatography/mass spectrometry.
Rapid communications in mass spectrometry : RCM 20060101
-
Multi-residue determination of non-steroidal anti-inflammatory drug residues in animal serum and plasma by HPLC and photo-diode array detection.
Journal of chromatographic science 20060101
-
Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials.
BMJ (Clinical research ed.) 20051224
-
Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile.
Bioorganic & medicinal chemistry 20051201
-
Study of structural features and thermodynamic parameters, determining the chromatographic behaviour of drug-cyclodextrin complexes.
Journal of chromatography. A 20050916
-
Prediction of genotoxicity of chemical compounds by statistical learning methods.
Chemical research in toxicology 20050601
-
Geriatric pharmacology.
The Veterinary clinics of North America. Small animal practice 20050501
-
Infrared studies of the polymorphic states of the fenamates.
Journal of pharmaceutical and biomedical analysis 20050309
-
Influence of marbofloxacin on the pharmacokinetics and pharmacodynamics of tolfenamic acid in calves.
Journal of veterinary pharmacology and therapeutics 20050201
-
PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology.
Journal of veterinary pharmacology and therapeutics 20041201
-
Compounds exhibiting selective efficacy for different beta subunits of human recombinant gamma-aminobutyric acid A receptors.
The Journal of pharmacology and experimental therapeutics 20041101
-
Pain management in cats--past, present and future. Part 2. Treatment of pain--clinical pharmacology.
Journal of feline medicine and surgery 20041001
-
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Bioorganic & medicinal chemistry letters 20040716
-
Attitudes and concerns of French veterinarians towards pain and analgesia in dogs and cats.
Veterinary anaesthesia and analgesia 20040701
-
Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs.
American journal of veterinary research 20040601
-
Migraine headache.
Clinical evidence 20040601
-
Binuclear copper(II) complexes of tolfenamic: synthesis, crystal structure, spectroscopy and superoxide dismutase activity.
Journal of inorganic biochemistry 20040201
-
Acute treatment of migraine. Breaking the paradigm of monotherapy.
BMC neurology 20040101
-
Rizatriptan versus rizatriptan plus rofecoxib versus rizatriptan plus tolfenamic acid in the acute treatment of migraine.
BMC neurology 20040101
-
Multi-residue liquid chromatography/tandem mass spectrometry method for the detection of non-steroidal anti-inflammatory drugs in bovine muscle: optimisation of ion trap parameters.
Rapid communications in mass spectrometry : RCM 20040101
-
Migraine headache.
Clinical evidence 20031201
-
Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study.
British journal of cancer 20030602
-
Determination of acidic drugs in sewage water by gas chromatography-mass spectrometry as tert.-butyldimethylsilyl derivatives.
Journal of chromatography. A 20030124
-
[Neurotransmitter mechanism of the tropoxin effect in comparison with other antimigraine preparations].
Eksperimental'naia i klinicheskaia farmakologiia 20030101
-
[Effectiveness of tolfenamic acid in the prevention of migraine].
Medicina (Kaunas, Lithuania) 20020101
-
Search of antimicrobial activity of selected non-antibiotic drugs.
Acta poloniae pharmaceutica 20020101
-
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Chemical communications (Cambridge, England) 20011121
-
Fenamates stimulate BKCa channel osteoblast-like MG-63 cells activity in the human.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20011101
-
Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug.
Arquivos de neuro-psiquiatria 20010901
-
Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.
Journal of analytical toxicology 20010101
-
A nonsteroidal anti-inflammatory drug, flufenamic acid, inhibits the expression of the androgen receptor in LNCaP cells.
Endocrinology 19991101
-
Human pharmacokinetics of tolfenamic acid, a new anti-inflammatory agent.
European journal of clinical pharmacology 19810101
