138-52-3 | Salicin

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$10.00	$7.00
5g	98%	in stock	$13.00	$9.00
10g	98%	in stock	$17.00	$12.00
25g	98%	in stock	$41.00	$29.00
100g	98%	in stock	$114.00	$80.00
500g	98%	in stock	$473.00	$331.00

Description

• Catalog Number: AA56575
• Chemical Name: Salicin
• CAS Number: 138-52-3
• Molecular Formula: C13H18O7
• Molecular Weight: 286.27781999999996
• MDL Number: MFCD00006590
• SMILES: OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@@H]([C@H]([C@@H]1O)O)O
• NSC Number: 758201

Computed Properties

• Complexity: 300
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 5
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 4
• XLogP3: -1.2

Literature

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  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Herbal medicine for low back pain.

  The Cochrane database of systematic reviews 20060419

• The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential.

  Cell proliferation 20060401

• Cloning and comparison of third beta-glucoside utilization (bglEFIA) operon with two operons of Pectobacterium carotovorum subsp. carotovorum LY34.

  Bioscience, biotechnology, and biochemistry 20060401

• Reclassification of Paenibacillus larvae subsp. pulvifaciens and Paenibacillus larvae subsp. larvae as Paenibacillus larvae without subspecies differentiation.

  International journal of systematic and evolutionary microbiology 20060301

• Inhibition activities of natural products on serine proteases.

  Phytotherapy research : PTR 20060301

• The expression of genes encoding lipodepsipeptide phytotoxins by Pseudomonas syringae pv. syringae is coordinated in response to plant signal molecules.

  Molecular plant-microbe interactions : MPMI 20060301

• Genomic variation in Streptococcus mutans: deletions affecting the multiple pathways of beta-glucoside metabolism.

  Oral microbiology and immunology 20060201

• Metabolic pathways variability and sequence/networks comparisons.

  BMC bioinformatics 20060101

• [The Italian contributions to the history of salicylates].

  Reumatismo 20060101

• Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence.

  Arthritis research & therapy 20060101

• Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada.

  Journal of ethnobiology and ethnomedicine 20060101

• Electrophysiological and behavioural characterization of gustatory responses to antennal 'bitter' taste in honeybees.

  The European journal of neuroscience 20051201

• Purification and characterization of an intracellular beta-glucosidase from the methylotrophic yeast Pichia pastoris.

  Biochemistry. Biokhimiia 20051201

• Stable isotope characterization of the ortho-oxygenated phenylpropanoids: coumarin and melilotol.

  Journal of agricultural and food chemistry 20051130

• Purification and characterization of two endo-beta-1,4-glucanases from mollusca, Ampullaria crossean.

  Acta biochimica et biophysica Sinica 20051001

• Pyrosequencing Bacillus anthracis.

  Emerging infectious diseases 20051001

• Lactobacillus concavus sp. nov., isolated from the walls of a distilled spirit fermenting cellar in China.

  International journal of systematic and evolutionary microbiology 20050901

• Analysis of carbohydrates in plants by high-performance anion-exchange chromatography coupled with electrospray mass spectrometry.

  Journal of chromatography. A 20050826

• A digestive beta-glucosidase from the silkworm, Bombyx mori: cDNA cloning, expression and enzymatic characterization.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050801

• Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae).

  Journal of agricultural and food chemistry 20050727

• Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16.

  Current biology : CB 20050726

• Semi-industrial isolation of salicin and amygdalin from plant extracts using slow rotary counter-current chromatography.

  Journal of chromatography. A 20050513

• Comparison of molecular mobility in the glassy state between amorphous indomethacin and salicin based on spin-lattice relaxation times.

  Pharmaceutical research 20050501

• Enzymatic synthesis and anti-coagulant effect of salicin analogs by using the Leuconostoc mesenteroides glucansucrase acceptor reaction.

  Journal of biotechnology 20050420

• Structural and biochemical analysis of the asc operon encoding 6-phospho-beta-glucosidase in Pectobacterium carotovorum subsp. carotovorum LY34.

  Research in microbiology 20050301

• [Arbutin, salicin: the possibilities of their biotechnological production].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20050301

• Purification and characterization of recombinant Escherichia coli-expressed Pichia etchellsii beta-glucosidase II with high hydrolytic activity on sophorose.

  Applied microbiology and biotechnology 20050201

• Emetic toxin formation of Bacillus cereus is restricted to a single evolutionary lineage of closely related strains.

  Microbiology (Reading, England) 20050101

• Emergence of unusual species of enterococci causing infections, South India.

  BMC infectious diseases 20050101

• Sample pretreatment and determination of non steroidal anti-inflammatory drugs (NSAIDs) in pharmaceutical formulations and biological samples (blood, plasma, erythrocytes) by HPLC-UV-MS and micro-HPLC.

  Current medicinal chemistry 20050101

• Aerococcus urinae: polyphasic characterization of the species.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20050101

• Genetic variability among Blastoschizomyces capitatus isolates from different clinical sources.

  International journal of immunopathology and pharmacology 20050101

• HPLC-MS/MS analysis of willow bark extracts contained in pharmaceutical preparations.

  Phytochemical analysis : PCA 20050101

• Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract.

  Arzneimittel-Forschung 20050101

• Differentiation of extractive and synthetic salicin. The 2H aromatic pattern of natural 2-hydroxybenzyl alcohol.

  Journal of agricultural and food chemistry 20041229

• Purification and characterization of an extracellular b-glucosidase with high transglucosylation activity and stability from Aspergillus niger No. 5.1.

  Applied biochemistry and biotechnology 20041201

• Bitter taste receptors for saccharin and acesulfame K.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110

• A randomized double-blind placebo-controlled clinical trial of a product containing ephedrine, caffeine, and other ingredients from herbal sources for treatment of overweight and obesity in the absence of lifestyle treatment.

  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20041101

• Analysis of bgl operon structure and characterization of beta-glucosidase from Pectobacterium carotovorum subsp. carotovorum LY34.

  Bioscience, biotechnology, and biochemistry 20041101

• The role of carboxyl, guanidine and imidazole groups in catalysis by a midgut trehalase purified from an insect larvae.

  Insect biochemistry and molecular biology 20041001

• Isolation and characterization of a cellulolytic Geobacillus thermoleovorans T4 strain from sugar refinery wastewater.

  Extremophiles : life under extreme conditions 20041001

• [Life threatening intestinal bleeding in a Bearded Collie associated with a food supplement for horses].

  Schweizer Archiv fur Tierheilkunde 20041001

• Sympodiomyces attinorum sp. nov., a yeast species associated with nests of the leaf-cutting ant Atta sexdens.

  International journal of systematic and evolutionary microbiology 20040901

• Catabolite repression and virulence gene expression in Listeria monocytogenes.

  Current microbiology 20040801

• Enzymatic synthesis of two salicin analogues by reaction of salicyl alcohol with Bacillus macerans cyclomaltodextrin glucanyltransferase and Leuconostoc mesenteroides B-742CB dextransucrase.

  Carbohydrate research 20040601

• Proposal to accommodate Burkholderia cepacia genomovar VI as Burkholderia dolosa sp. nov.

  International journal of systematic and evolutionary microbiology 20040501

• Isolation of salicin derivatives from Homalium cochinchinensis and their antiviral activities.

  Journal of natural products 20040401

• Optimization of carbohydrate silylation for gas chromatography.

  Journal of chromatography. A 20040220

• Effects of an ethanolic salix extract on the release of selected inflammatory mediators in vitro.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20040201

• Identification of aryl-phospho-beta-D-glucosidases in Bacillus subtilis.

  Archives of microbiology 20040101

• [Purification of lectin from perch (Persa fluviatilis L.) roe specific to cellobiose and study of its characteristics].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101

• Increased mortality of gypsy moth Lymantria dispar (L.) (Lepidoptera: Lymantriidae) exposed to gypsy moth nuclear polyhedrosis virus in combination with the phenolic gycoside salicin.

  Journal of economic entomology 20031201

• Substrate specificity of the Arabidopsis thaliana sucrose transporter AtSUC2.

  The Journal of biological chemistry 20031107

• The effect of willow leaf extracts on human leukemic cells in vitro.

  Journal of biochemistry and molecular biology 20030731

• Prediction of the relaxation behavior of amorphous pharmaceutical compounds. I. Master curves concept and practice.

  Journal of pharmaceutical sciences 20030701

• Trade-off between synthesis of salicylates and growth of micropropagated Salix pentandra.

  Journal of chemical ecology 20030701

• The beta-glucoside genes of Klebsiella aerogenes: conservation and divergence in relation to the cryptic bgl genes of Escherichia coli.

  FEMS microbiology letters 20030627

• Purification and characterization of two beta-glucosidases from a thermo-tolerant yeast Pichia etchellsii.

  Biochimica et biophysica acta 20030626

• A single V317A or V317M substitution in Enzyme II of a newly identified beta-glucoside phosphotransferase and utilization system of Corynebacterium glutamicum R extends its specificity towards cellobiose.

  Microbiology (Reading, England) 20030601

• Purification and characterization of vanilla bean (Vanilla planifolia Andrews) beta-D-glucosidase.

  Journal of agricultural and food chemistry 20030507

• Salicin and treatment of rheumatic diseases.

  The Journal of rheumatology 20030501

• Aeromonas hydrophila subsp. ranae subsp. nov., isolated from septicaemic farmed frogs in Thailand.

  International journal of systematic and evolutionary microbiology 20030501

• In vitro degradation of willow salicylates.

  Journal of chemical ecology 20030501

• Influence of willow bark extract on cyclooxygenase activity and on tumor necrosis factor alpha or interleukin 1 beta release in vitro and ex vivo.

  Clinical pharmacology and therapeutics 20030301

• Staphylococcus equorum subsp. linens, subsp. nov., a starter culture component for surface ripened semi-hard cheeses.

  Systematic and applied microbiology 20030301

• Modification of an approved medium for fecal coliform detection in seawater: A-1 medium minus salicin.

  Journal of food protection 20030101

• Effects of willow hybridisation and simulated browsing on the development and survival of the leaf beetle Phratora vitellinae.

  BMC ecology 20030101

• Taste and pheromone perception in mammals and flies.

  Genome biology 20030101

• Burkholderia cepacia complex genomovars: utilization of carbon sources, susceptibility to antimicrobial agents and growth on selective media.

  Journal of applied microbiology 20030101

• The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

  Nature genetics 20021101

• Characterization of an extracellular salicyl alcohol oxidase from larval defensive secretions of Chrysomela populi and Phratora vitellinae (Chrysomelina).

  Insect biochemistry and molecular biology 20021101

• Lactobacillus pantheris sp. nov., isolated from faeces of a jaguar.

  International journal of systematic and evolutionary microbiology 20020901

• Contribution of different taste cells and signaling pathways to the discrimination of 'bitter' taste stimuli by an insect.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815

• Evaluation of salicin as an antipyretic prodrug that does not cause gastric injury.

  Planta medica 20020801

• Phenotypic and genotypic properties of the genus Hafnia.

  Journal of medical microbiology 20020701

• The treatment of acute rheumatism by salicin, by T.J. Maclagan--The Lancet, 1876.

  The Journal of rheumatology 20020601

• Laccase down-regulation causes alterations in phenolic metabolism and cell wall structure in poplar.

  Plant physiology 20020501

• Weissella kimchii sp. nov., a novel lactic acid bacterium from kimchi.

  International journal of systematic and evolutionary microbiology 20020301

• Phenolic glucosides from Alangium plantanifolium.

  Journal of Asian natural products research 20020301

• [Pain management with herbal antirheumatic drugs].

  Wiener medizinische Wochenschrift (1946) 20020101

• [Willow bark extract--effects and effectiveness. Status of current knowledge regarding pharmacology, toxicology and clinical aspects].

  Wiener medizinische Wochenschrift (1946) 20020101

• Treatment of low back pain with a herbal or synthetic anti-rheumatic: a randomized controlled study. Willow bark extract for low back pain.

  Rheumatology (Oxford, England) 20011201

• Selective adaptation to noxious foods by a herbivorous insect.

  The Journal of experimental biology 20011001

• Purification and characterization of a beta-glucosidase from Citrus sinensis var. Valencia fruit tissue.

  Journal of agricultural and food chemistry 20010901

• [Determination of salicin in extract of willow bark by high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20010901

• Differences in host use efficiency of larvae of a generalist moth, Operophtera brumata on three chemically divergent Salix species.

  Journal of chemical ecology 20010801

• Pharmacokinetics of salicin after oral administration of a standardised willow bark extract.

  European journal of clinical pharmacology 20010801

• An evolutionary alternative system for aryl beta-glucosides assimilation in bacteria.

  Journal of molecular microbiology and biotechnology 20010701

• Potential economic impact of using a proprietary willow bark extract in outpatient treatment of low back pain: an open non-randomized study.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20010701

• Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.

  Journal of chemical ecology 20010601

• Water-soluble organometallic catalysts from carbohydrates. 2. A strategy for the preparation of catalysts with pendant quaternary ammonium groups using D-salicin.

  The Journal of organic chemistry 20010518

• Effect of salicis cortex extract on human platelet aggregation.

  Planta medica 20010401

• [Development of chromogenic agar medium for isolation of enterohaemorrhagic Escherichia coli O26].

  Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20010401

• Plants as de-worming agents of livestock in the Nordic countries: historical perspective, popular beliefs and prospects for the future.

  Acta veterinaria Scandinavica 20010101

• [Effect of human serum albumin on transport of drugs through human erythrocyte membranes].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 19960801