138199-51-6 | 2-Amino-2-(2H-tetrazol-5-yl)acetic acid

Packsize	Purity	Availability	Price	Discounted Price
10mg	≥95%	in stock	$156.00	$109.00
25mg	≥95%	in stock	$369.00	$259.00
50mg	≥95%	in stock	$699.00	$489.00

Description

• Catalog Number: AA57167
• Chemical Name: 2-Amino-2-(2H-tetrazol-5-yl)acetic acid
• CAS Number: 138199-51-6
• Molecular Formula: C3H5N5O2
• Molecular Weight: 143.1041
• MDL Number: MFCD00233633
• SMILES: OC(=O)C(c1n[nH]nn1)N

Computed Properties

• Complexity: 139
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 2
• Undefined Atom Stereocenter Count: 1
• XLogP3: -4.1

Literature

• Seizure responses and induction of Fos by the NMDA agonist (tetrazol-5-yl)glycine in a genetic model of NMDA receptor hypofunction.

  Brain research 20080724

• Pharmacological characterization of ligands at recombinant NMDA receptor subtypes by electrophysiological recordings and intracellular calcium measurements.

  Combinatorial chemistry & high throughput screening 20080501

• Assessment of NMDA receptor activation in vivo by Fos induction after challenge with the direct NMDA agonist (tetrazol-5-yl)glycine: effects of clozapine and haloperidol.

  Journal of neural transmission (Vienna, Austria : 1996) 20070701

• Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist.

  Bioorganic & medicinal chemistry 20010201

• Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.

  Neurochemistry international 20010101