1420477-60-6 | Acalabrutinib

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$34.00	$24.00
25mg	95%	in stock	$87.00	$61.00
50mg	95%	in stock	$111.00	$78.00
100mg	95%	in stock	$122.00	$85.00
250mg	95%	in stock	$235.00	$164.00
1g	95%	in stock	$606.00	$424.00

Description

• Catalog Number: AA69292
• Chemical Name: Acalabrutinib
• CAS Number: 1420477-60-6
• Molecular Formula: C26H23N7O2
• Molecular Weight: 465.5065
• MDL Number: MFCD29472294
• SMILES: CC#CC(=O)N1CCC[C@H]1c1nc(c2n1ccnc2N)c1ccc(cc1)C(=O)Nc1ccccn1

Computed Properties

• Complexity: 845
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 3

Literature

• Mantle Cell Lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20160410

• Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.

  The New England journal of medicine 20160128

• Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor.

  Journal of hematology & oncology 20160101