143824-78-6 | Fmoc-Trp(Boc)-OH

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$16.00	$11.00
5g	97%	in stock	$18.00	$12.00
10g	97%	in stock	$25.00	$18.00
25g	97%	in stock	$44.00	$31.00
100g	97%	in stock	$174.00	$122.00

Description

• Catalog Number: AA70350
• Chemical Name: Fmoc-Trp(Boc)-OH
• CAS Number: 143824-78-6
• Molecular Formula: C31H30N2O6
• Molecular Weight: 526.5797
• MDL Number: MFCD00153366
• SMILES: O=C(N[C@H](C(=O)O)Cc1cn(c2c1cccc2)C(=O)OC(C)(C)C)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 880
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 39
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9
• XLogP3: 6

Upstream Synthesis Route

Fmoc-Trp(Boc)-OH is a commonly used building block in chemical synthesis, specifically in peptide chemistry. This compound is an amino acid derivative that contains both an Fmoc (9-fluorenylmethoxycarbonyl) protecting group and a Boc (tert-butoxycarbonyl) protecting group on the side chain of tryptophan. In peptide synthesis, the Fmoc group serves as a temporary protecting group for the amine group of the tryptophan residue, allowing selective deprotection and coupling of amino acids in a controlled manner. The Boc group on the side chain provides protection for the indole nitrogen, ensuring its stability during the synthesis process.Overall, Fmoc-Trp(Boc)-OH is a versatile building block that enables chemists to efficiently and selectively incorporate tryptophan into peptide sequences, making it an essential tool in the synthesis of complex peptides and peptidomimetics.